Diseases. 2025 Jul 14. pii: 220. [Epub ahead of print]13(7):
Tomasz Machałowski,
Piotr Gutowski,
Edyta Zagrodnik,
Aleksandra Godlewska,
Katarzyna Śmieja,
Oliwia Kawałek,
Anna Grzymała-Figura,
Sylwester Michał Ciećwież,
Katarzyna Gross-Kępińska,
Małgorzata Szczuko,
Maciej Ziętek.
BACKGROUND: Liposarcoma (LPS) is a rare malignant tumor, but it is also one of the most common adult soft-tissue sarcomas. Myxoid liposarcoma (MLPS) accounts for 30% of all LPS cases. Diagnosis during pregnancy and the puerperium is very rarely reported, and only a few cases have been reported in the thigh.
CASE PRESENTATION: We report the case of a 36-year-old female patient on the 11th day of the puerperium after a cesarean section. The patient presented to the gynecology ward owing to the sudden appearance of a tumor in the medial part of her right thigh. The lesion was non-painful, mobile, soft, approximately 20 cm in diameter, and protruded above the level of the rest of the thigh surface. A suspicion of hematoma was raised. The final diagnosis was high-grade MLPS.
CONCLUSIONS: An MLPS diagnosis is uncommon in female patients and even rarer during pregnancy. This case represents a novel occurrence, as the first instance in which symptoms manifested during the puerperium. Proper treatment and early detection could improve disease outcomes.
Keywords: myxoid liposarcoma; pregnancy; puerperium; sarcoma