bims-librar Biomed News
on Biomedical librarianship
Issue of 2018‒12‒16
thirty-nine papers selected by
Thomas Krichel
Open Library Society


  1. Int J Med Inform. 2019 Jan;pii: S1386-5056(18)30269-7. [Epub ahead of print]121 10-18
      OBJECTIVE: Reproducibility of research studies is key to advancing biomedical science by building on sound results and reducing inconsistencies between published results and study data. We propose that the available data from research studies combined with provenance metadata provide a framework for evaluating scientific reproducibility. We developed the ProvCaRe platform to model, extract, and query semantic provenance information from 435, 248 published articles.METHODS: The ProvCaRe platform consists of: (1) the S3 model and a formal ontology; (2) a provenance-focused text processing workflow to generate provenance triples consisting of subject, predicate, and object using metadata extracted from articles; and (3) the ProvCaRe knowledge repository that supports "provenance-aware" hypothesis-driven search queries. A new provenance-based ranking algorithm is used to rank the articles in the search query results.
    RESULTS: The ProvCaRe knowledge repository contains 48.9 million provenance triples. Seven research hypotheses were used as search queries for evaluation and the resulting provenance triples were analyzed using five categories of provenance terms. The highest number of terms (34%) described provenance related to population cohort followed by 29% of terms describing statistical data analysis methods, and only 5% of the terms described the measurement instruments used in a study. In addition, the analysis showed that some articles included a higher number of provenance terms across multiple provenance categories suggesting a higher potential for reproducibility of these research studies.
    CONCLUSION: The ProvCaRe knowledge repository (https://provcare.
    CASE: edu/) is one of the largest provenance resources for biomedical research studies that combines intuitive search functionality with a new provenance-based ranking feature to list articles related to a search query.
    Keywords:  ProvCaRe knowledge repository; ProvCaRe ontology; Provenance metadata; Provenance-based ranking; S3 model; Scientific reproducibility; W3C PROV specifications
    DOI:  https://doi.org/10.1016/j.ijmedinf.2018.10.009
  2. Proc Natl Acad Sci U S A. 2018 Dec 11. 115(50): 12603-12607
      Experience plays a critical role in crafting high-impact scientific work. This is particularly evident in top multidisciplinary journals, where a scientist is unlikely to appear as senior author if he or she has not previously published within the same journal. Here, we develop a quantitative understanding of author order by quantifying this "chaperone effect," capturing how scientists transition into senior status within a particular publication venue. We illustrate that the chaperone effect has a different magnitude for journals in different branches of science, being more pronounced in medical and biological sciences and weaker in natural sciences. Finally, we show that in the case of high-impact venues, the chaperone effect has significant implications, specifically resulting in a higher average impact relative to papers authored by new principal investigators (PIs). Our findings shed light on the role played by experience in publishing within specific scientific journals, on the paths toward acquiring the necessary experience and expertise, and on the skills required to publish in prestigious venues.
    Keywords:  mentorship; science of science; scientific careers
    DOI:  https://doi.org/10.1073/pnas.1800471115
  3. Scientometrics. 2018 ;117(3): 1587-1609
      Editors of scientific journals meet increasing challenges to find peer reviewers. Rewarding reviewers has been proposed as a solution to incentives peer review, and journals have already started to offer different kinds of rewards, particularly non-monetary ones. However, research so far has mainly explored the efficacy of monetary rewards, while research on non-monetary rewards is barely absent. The goal of this article is to fill this gap by exploring whether and under what conditions a rather common non-monetary reward employed by journals, i.e., to recognize reviewers work by publishing their names on a yearly issue, is effective in increasing the willingness of scientists to become peer reviewers. We test the efficacy of three different reward settings identified in the literature: (1) engagement contingent, (2) task-completion contingent, and (3) performance contingent, through a natural experiment involving 1865 scientists in faculties of business and economics of Romanian universities. We explore whether reward efficacy varies across scientists depending on their gender, academic rank, research productivity, and type of institution to which they are affiliated. The results show that the performance contingency strongly reduces the number of respondents willing to become reviewers (- 60 % compared to a no-reward setting), particularly males and research productive scientists. Scientists affiliated with private universities are strongly discouraged by the reward. In sum, the results suggest that non-monetary rewards are not necessarily effective, as in some cases they may actually discourage the most intrinsically motivated and competent reviewers.
    Keywords:  Engagement incentives; Motivations; Non-monetary rewards; Peer review; Performance based incentives; Task-completion incentives
    DOI:  https://doi.org/10.1007/s11192-018-2912-6
  4. Nature. 2018 Dec;564(7735): S70-S71
      
    Keywords:  Publishing; Research management
    DOI:  https://doi.org/10.1038/d41586-018-07695-1
  5. J Biomed Inform. 2018 Dec 06. pii: S1532-0464(18)30227-2. [Epub ahead of print]
      Scientific knowledge constitutes a complex system that has recently been the topic of in-depth analysis. Empirical evidence reveals that little is known about the dynamic aspects of human knowledge. Precise dissection of the expansion of scientific knowledge could help us to better understand the evolutionary dynamics of science. In this paper, we analyzed the dynamic properties and growth principles of the MEDLINE bibliographic database using network analysis methodology. The basic assumption of this work is that the scientific evolution of the life sciences can be represented as a list of co-occurrences of MeSH descriptors that are linked to MEDLINE citations. The MEDLINE database was summarized as a complex system, consisting of nodes and edges, where the nodes refer to knowledge concepts and the edges symbolize corresponding relations. We performed an extensive statistical evaluation based on more than 25 million citations in the MEDLINE database, from 1966 until 2014. We based our analysis on node and community level in order to track temporal evolution in the network. The degree distribution of the network follows a stretched exponential distribution which prevents the creation of large hubs. Results showed that the appearance of new MeSH terms does not also imply new connections. The majority of new connections among nodes results from old MeSH descriptors. We suggest a wiring mechanism based on the theory of structural holes, according to which a novel scientific discovery is established when a connection is built among two or more previously disconnected parts of scientific knowledge. Overall, we extracted 142 different evolving communities. It is evident that new communities are constantly born, live for some time, and then die. We also provide a Web-based application that helps characterize and understand the content of extracted communities. This study clearly shows that the evolution of MEDLINE knowledge correlates with the network's structural and temporal characteristics.
    Keywords:  Bibliographic databases; Complex networks; MEDLINE; Network evolution; Science of science
    DOI:  https://doi.org/10.1016/j.jbi.2018.11.014
  6. BMC Public Health. 2018 Dec 07. 18(1): 1356
      BACKGROUND: Lung cancer screening can reduce mortality but can be a complex, multi-step process. Poor health literacy is associated with unfavorable outcomes and decreased use of preventative services, so it is important to address barriers to care through efficient and practical education. The readability of lung cancer screening materials for patients is unknown and may not be at the recommended 6th grade reading level set by the American Medical Association. Our goals were to: (1) measure the health literacy of a lung cancer screening population from an urban academic medical center, and (2) examine the readability of online educational materials for lung cancer screening.METHODS: We performed a retrospective cross sectional study at a single urban academic center. Health literacy was assessed using three validated screening questions. To assess the readability of educational materials, we performed a Google search using the phrase, "What is lung cancer screening?" and the Flesch-Kincaid Grade Level (FKGL) formula was used to estimate the grade level required to understand the text.
    RESULTS: There were 404 patients who underwent lung cancer screening during the study period. The prevalence of inadequate/marginal health literacy was 26.7-38.0%. Fifty websites were reviewed and four were excluded from analysis because they were intended for medical providers. The mean FKGL for the 46 websites combined was 10.6 ± 2.2.
    CONCLUSIONS: Low health literacy was common and is likely a barrier to appropriate education for lung cancer screening. The current online educational materials regarding lung cancer screening are written above the recommended reading level set by the American Medical Association.
    Keywords:  Health literacy; Lung cancer screening; Patient education
    DOI:  https://doi.org/10.1186/s12889-018-6278-8
  7. Int J Environ Res Public Health. 2018 Dec 09. pii: E2787. [Epub ahead of print]15(12):
      The Internet and social media is an enormous source of information. Health social networks and online collaborative environments enable users to create shared content that afterwards can be discussed. The aim of this paper is to present a novel methodology designed for quantifying relevant information provided by different participants in clinical online discussions. The main goal of the methodology is to facilitate the comparison of participant interactions in clinical conversations. A set of key indicators for different aspects of clinical conversations and specific clinical contributions within a discussion have been defined. Particularly, three new indicators have been proposed to make use of biomedical knowledge extraction based on standard terminologies and ontologies. These indicators allow measuring the relevance of information of each participant of the clinical conversation. Proposed indicators have been applied to one discussion extracted from PatientsLikeMe, as well as to two real clinical cases from the Sanar collaborative discussion system. Results obtained from indicators in the tested cases have been compared with clinical expert opinions to check indicators validity. The methodology has been successfully used for describing participant interactions in real clinical cases belonging to a collaborative clinical case discussion tool and from a conversation from a health social network. This work can be applied to assess collaborative diagnoses, discussions among patients, and the participation of students in clinical case discussions. It permits moderators and educators to obtain a quantitatively measure of the contribution of each participant.
    Keywords:  collaboration measurement; conversation participation indicators; health; healthcare professionals; medical terminologies; patients; social media
    DOI:  https://doi.org/10.3390/ijerph15122787
  8. Ugeskr Laeger. 2018 Dec 10. pii: V70033. [Epub ahead of print]180(50):
      INTRODUCTION: Predatory publishing has led to an increasing amount of scientific spam mails addressed to medical researchers. This study aimed at characterising this spam further.METHODS: Prospective study of spam received during a three-month-period.
    RESULTS: A total of 137 spam e-mails with scientific contents were received. The majority (88%) was automatically led to the spam filter. The mails represented various invitations from journals (77%), conferences (19%) and other (4%). Most of the mails used titles, had opening lines or flattery contents, and spelling, grammar or layout errors were common.
    CONCLUSION: Since spam filters are not completely accurate, screening is often necessary, however, responding to unsolicited predatory scientific spam should be avoided.
  9. Health Mark Q. 2018 Dec 14. 1-18
      This study examines how consumers who responded to direct-to-consumer (DTC) prescription drug advertising by either talking with their doctors or seeking the Internet differ from those who did not respond to DTC advertising in a number of meaningful ways. This exploratory study provides an initial look at factors that are influential in discriminating information responders from nonresponders to DTC Rx ads. Consumers more attentive to and having more positive attitudes towards Rx ads and consumers having lower trust in their doctors and perceiving higher empowerment by Rx ads are more likely to respond for additional information after seeing Rx ads.
    Keywords:  DTC advertising; asking a doctor; consumers’ actions; prescription drug advertising; referring to the Internet
    DOI:  https://doi.org/10.1080/07359683.2018.1514735
  10. BMC Med. 2018 Dec 14. 16(1): 233
      There is clear guidance on the responsibilities of editors to ensure that the research they publish is of the highest possible quality. Poor reporting is unethical and directly impacts patient care. Reporting guidelines are a relatively recent development to help improve the accuracy, clarity, and transparency of biomedical publications. They have caught on, with hundreds of reporting guidelines now available. Some journals endorse reporting guidelines while a smaller number have used various approaches to implement them. Yet challenges remain - biomedical research is still not optimally reported despite the abundance of reporting guidelines. Electronic algorithms are now being developed to facilitate the choice of correct reporting guideline(s), while other tools are being integrated into journal editorial management processes. Universities need to consider whether it is responsible to advance careers of faculty based on poorly reported research which is of little societal value. If journals embraced auditing of the quality of articles they publish this would give them and their readers essential feedback from which to improve their product.
    Keywords:  EQUATOR; Quality of reporting; audit and feedback; evidence; reporting guidelines; reproducibility
    DOI:  https://doi.org/10.1186/s12916-018-1226-0
  11. Scientometrics. 2018 ;117(3): 1453-1478
      The importance of achieving high quality in research practice has been highlighted in different disciplines. At the same time, citations are utilized to measure the impact of academic researchers and institutions. One open question is whether the quality in the reporting of research is related to scientific impact, which would be desired. In this exploratory study we aim to: (1) Investigate how consistently a scoring rubric for rigor and relevance has been used to assess research quality of software engineering studies; (2) Explore the relationship between rigor, relevance and citation count. Through backward snowball sampling we identified 718 primary studies assessed through the scoring rubric. We utilized cluster analysis and conditional inference tree to explore the relationship between quality in the reporting of research (represented by rigor and relevance) and scientiometrics (represented by normalized citations). The results show that only rigor is related to studies' normalized citations. Besides that, confounding factors are likely to influence the number of citations. The results also suggest that the scoring rubric is not applied the same way by all studies, and one of the likely reasons is because it was found to be too abstract and in need to be further refined. Our findings could be used as a basis to further understand the relation between the quality in the reporting of research and scientific impact, and foster new discussions on how to fairly acknowledge studies for performing well with respect to the emphasized research quality. Furthermore, we highlighted the need to further improve the scoring rubric.
    Keywords:  Conditional inference tree; Empirical software engineering; Exploratory study; Reporting of research; Research practice; Scientific impact
    DOI:  https://doi.org/10.1007/s11192-018-2907-3
  12. Early Hum Dev. 2018 Dec 07. pii: S0378-3782(18)30723-0. [Epub ahead of print]
      Evidence-based published data is the prime source used for clinical decision making, the issuance of guidelines and the drafting new policies. A number of different study designs are used to perform and publish research studies, corresponding to the research question being investigated. Over the decades, a hierarchical system of evidence has been established. This provides an indication of the level of evidence each study design contributes to the research community. Policies and clinical guidelines should naturally be based on the highest level of evidence data available. However, the highest level of evidence study designs may not always provide an adequate answer to a research question. Thus, when utilising published evidence-based data, one should first understand the clinical question that needs to be answered, and then critically appraise the published data accordingly.
    Keywords:  Clinical practice guideline; Evidence-based medicine; Publications; Research; Research design
    DOI:  https://doi.org/10.1016/j.earlhumdev.2018.12.004
  13. Educ Health (Abingdon). 2018 May-Aug;31(2):31(2): 130-133
      Background: Medical educators provide service by developing curricula and writing learning material. In addition, academic institutions expect medical educators to publish scholarship to be considered for promotion and academic advancement. Unfortunately, educators may receive limited time to execute these duties and expectations. One way medical educators can streamline their workload is by publishing educational coursework they have previously written into an e-book through an online publisher. This allows them to transform educational service they have already completed into scholarship required for academic recognition, thus maximizing the efficient use of their time.Intervention: Publishing educational material as an e-book requires four steps. First, medical educators must determine which of their educational materials is best suited for publishing as an e-book. Second, educators must rank the features of each e-book publisher and choose the one that best meets their needs. Third, the educational material must be adapted as a manuscript and submitted for publication. Finally, the e-book must be advertised, promoted, and distributed to its intended audience. In addition, the success of the project should be evaluated. To illustrate this process, we describe the steps we took to publish the learning material we created for our internal medicine residents into an e-book.
    Lessons Learned: The overall process took approximately 3 months and went smoothly. For future publications, we would determine better ways to track the number of downloads of the e-book, ensure all of our images are adequately large, and consider the use of academic, rather than commercial e-book publishers.
    Keywords:  Academic promotion; E-book publishing; medical curriculum; medical educators; publishing scholarship
    DOI:  https://doi.org/10.4103/efh.EfH_75_17
  14. J Med Internet Res. 2018 Dec 06. 20(12): e11817
      BACKGROUND: The content produced by individuals on various social media platforms has been successfully used to identify mental illness, including depression. However, most of the previous work in this area has focused on user-generated content, that is, content created by the individual, such as an individual's posts and pictures. In this study, we explored the predictive capability of community-generated content, that is, the data generated by a community of friends or followers, rather than by a sole individual, to identify depression among social media users.OBJECTIVE: The objective of this research was to evaluate the utility of community-generated content on social media, such as comments on an individual's posts, to predict depression as defined by the clinically validated Patient Health Questionnaire-8 (PHQ-8) assessment questionnaire. We hypothesized that the results of this research may provide new insights into next generation of population-level mental illness risk assessment and intervention delivery.
    METHODS: We created a Web-based survey on a crowdsourcing platform through which participants granted access to their Instagram profiles as well as provided their responses to PHQ-8 as a reference standard for depression status. After data quality assurance and postprocessing, the study analyzed the data of 749 participants. To build our predictive model, linguistic features were extracted from Instagram post captions and comments, including multiple sentiment scores, emoji sentiment analysis results, and meta-variables such as the number of likes and average comment length. In this study, 10.4% (78/749) of the data were held out as a test set. The remaining 89.6% (671/749) of the data were used to train an elastic-net regularized linear regression model to predict PHQ-8 scores. We compared different versions of this model (ie, a model trained on only user-generated data, a model trained on only community-generated data, and a model trained on the combination of both types of data) on a test set to explore the utility of community-generated data in our predictive analysis.
    RESULTS: The 2 models, the first trained on only community-generated data (area under curve [AUC]=0.71) and the second trained on a combination of user-generated and community-generated data (AUC=0.72), had statistically significant performances for predicting depression based on the Mann-Whitney U test (P=.03 and P=.02, respectively). The model trained on only user-generated data (AUC=0.63; P=.11) did not achieve statistically significant results. The coefficients of the models revealed that our combined data classifier effectively amalgamated both user-generated and community-generated data and that the 2 feature sets were complementary and contained nonoverlapping information in our predictive analysis.
    CONCLUSIONS: The results presented in this study indicate that leveraging community-generated data from social media, in addition to user-generated data, can be informative for predicting depression among social media users.
    Keywords:  depression; machine learning; mental health; social media
    DOI:  https://doi.org/10.2196/11817
  15. JMIR Cancer. 2018 Dec 13. 4(2): e10676
      BACKGROUND: Patients diagnosed with melanoma frequently search the internet for treatment information, including novel and complex immunotherapy. However, health literacy is limited among half of the German population, and no assessment of websites on melanoma treatment has been performed so far.OBJECTIVE: The aim of this study was to identify and assess the most visible websites in German language on melanoma immunotherapy.
    METHODS: In accordance with the common Web-based information-seeking behavior of patients with cancer, the first 20 hits on Google, Yahoo, and Bing were searched for combinations of German synonyms for "melanoma" and "immunotherapy" in July 2017. Websites that met our predefined eligibility criteria were considered for assessment. Three reviewers independently assessed their quality by using the established DISCERN tool and by checking the presence of quality certification. Usability and reliability were evaluated by the LIDA tool and understandability by the Patient Education Materials Assessment Tool (PEMAT). The Flesch Reading Ease Score (FRES) was calculated to estimate the readability. The ALEXA and SISTRIX tools were used to investigate the websites' popularity and visibility. The interrater agreement was determined by calculating Cronbach alpha. Subgroup differences were identified by t test, U test, or one-way analysis of variance.
    RESULTS: Of 480 hits, 45 single websites from 30 domains were assessed. Only 2 website domains displayed a German quality certification. The average assessment scores, mean (SD), were as follows: DISCERN, 48 (7.6); LIDA (usability), 40 (2.0); LIDA (reliability), 10 (1.6); PEMAT, 69% (16%); and FRES, 17 (14), indicating mediocre quality, good usability, and understandability but low reliability and an even very low readability of the included individual websites. SISTRIX scores ranged from 0 to 6872 and ALEXA scores ranged from 17 to 192,675, indicating heterogeneity of the visibility and popularity of German website domains providing information on melanoma immunotherapy.
    CONCLUSIONS: Optimization of the most accessible German websites on melanoma immunotherapy is desirable. Especially, simplification of the readability of information and further adaption to reliability criteria are required to support the education of patients with melanoma and laypersons, and to enhance transparency.
    Keywords:  immunotherapy; information; internet; melanoma; patient education; quality; readability; reliability; websites
    DOI:  https://doi.org/10.2196/10676
  16. J Surg Res. 2019 Feb;pii: S0022-4804(18)30669-3. [Epub ahead of print]234 139-148
      BACKGROUND: The gold standard for research is publication within a peer-reviewed journal. There is a discrepancy between the number of abstracts presented at scientific meetings and the number published as full articles. We identified publication rates for the 2012 meetings of four British surgical societies. These were the Association of Surgeons of Great Britain & Ireland (ASGBI), the Vascular Society of Great Britain and Ireland, the British Transplantation Society (BTS), and the Association of Coloproctology of Great Britain and Ireland (ACPGBI). We also compared publication rates with these societies' 2001 meetings and identified univariate factors associated with publication.MATERIALS AND METHODS: PubMed was searched to identify publications stemming from meeting abstracts. We extracted abstract characteristics to identify factors associated with publication and also characteristics of subsequent publications to enable comparison.
    RESULTS: Publication rates were 24.1% (ASGBI), 24.6% (BTS), 21.7% (ACPGBI), and 39.4% (Vascular Society of Great Britain and Ireland). Rates for ASGBI, BTS, and ACPGBI meetings were significantly lower compared to 2001 meetings (P = 0.001-0.026). Mean time to publication was 12.1-22.0 mo. Mean 5-y impact factor differed significantly between meetings (P = 0.001), with the BTS meeting having the highest mean 5-y impact factor (4.658). Factors associated with publication included being an oral presentation (ASGBI P = 0.001), multi-institution study (ASGBI P = 0.003), or randomized-controlled trial (BTS P = 0.049).
    CONCLUSIONS: Reduced publication rates may represent increased acceptance of low-quality abstracts at meetings or a more competitive journal submission process. Further data are required to strengthen conclusions. Nonetheless, authors and meeting organizers should push for higher quality abstracts to promote future peer-reviewed journal publication.
    Keywords:  Conferences; Impact factor; Meeting abstracts; Publications; Scientific meetings; Surgery
    DOI:  https://doi.org/10.1016/j.jss.2018.09.047
  17. Pflege. 2018 Dec 14. 1-10
      Publications German-speaking countries in high impact journals: development and validation of a search filter Abstract.BACKGROUND: The number of publications in journals with a high impact factor is an indication of a discipline's participation in international discourse. A search filter allows reliable and reproducible searches for specific publications.
    AIM: Development and validation of a geographic search filter for publications by nursing scientists affiliated to German-speaking countries in nursing journals with a high impact factor.
    METHODS: The search filter was objectively developed following several steps: (i) creation of a development and a validation set, each consisting of relevant and non-relevant publications, (ii) generation of the search filter by means of text analysis of the development set, (iii) internal validation based on the development set and (iv) external validation using the validation set. The validity was examined regarding several accuracy parameters, e. g. sensitivity, specificity, positive predictive value (PPV) and number needed to read (NNR).
    RESULTS: The search filter correctly identified 22 of 30 relevant and 16 of 21 non-relevant publications in the development set: sensitivity 80 % (95 % CI 66 - 94), specificity 76 % (95 % CI 58 - 94), PPV 83 % (95 % CI 69 - 97). External validation yielded similar or better results: sensitivity 81 % (95 % CI 67 - 96), specificity 88 % (95 % CI 71 - 100), PPV 88 % (95 % CI 75 - 100). The NNR was 1.2 and 1.1, respectively.
    CONCLUSIONS: The search filter has the potential to identify the intended publications.
    Keywords:  Datenbankrecherche; High Impact Journal; Impact Factor; Information Storage and Retrieval; Journal Impact Factor; Nursing Research; Pflegeforschung; Search Filter; Suchfilter
    DOI:  https://doi.org/10.1024/1012-5302/a000658
  18. Vet World. 2018 Nov;11(10): 1409-1415
      Aim: This study was designed to evaluate the network productions and research collaborations on toxoplasmosis worldwide.Materials and Methods: A bibliometric research was carried out using the Web of Science (WOS) database. The analysis unit was the original research articles about toxoplasmosis published between 2000 and 2016 (17 years).
    Results: Totally, 6,550 articles about toxoplasmosis were indexed in the WOS with the following information: (A) 18,410 researchers played a role in drafting the articles; (B) 33 different countries have contributed in the toxoplasmosis studies; (C) the USA was ranked at the first place with 2,162 publications about toxoplasmosis; and (D) "Dubey JP" was compiled and participated in 401 articles from the USA, as the highest number and main core of publications in the toxoplasmosis network.
    Conclusion: The main focus of the toxoplasmosis research activities in the world was article production in the indexed journals in WOS. Hence, it is necessary to strengthen the collaboration networks to improve the quality of articles. Furthermore, the priority would be the identification of institutions with a higher number of research article productions in WOS, to perform toxoplasmosis collaborative original researches according to the strategic roadmap and scientific plan of each country.
    Keywords:  Toxoplasma spp; Web of Science; bibliometric; scientific collaboration; toxoplasmosis
    DOI:  https://doi.org/10.14202/vetworld.2018.1409-1415
  19. Heliyon. 2018 Nov;4(11): e00964
      The aim of this bibliometric analysis is to review the status and research evolution on the analysis of polybrominated diphenyl ethers (PBDEs) on biological and environmental matrices from January 1992 to February 2018 in the Web of Science focusing on original articles and reviews. One thousand four hundred and eighty two articles were found in the databases of the Web of Science on the analysis of PBDEs. Quantitative and qualitative parameters (countries, number of articles, frequency, average article citations and total average citations) were used to analyse each article and ranking of countries based on productivity, authors and article citation. Complementary analysis based on keywords was also done. The last decade experienced an increase in the analysis of this pollutant with the year 2012 recording the highest number of published articles (n = 137). High rate of collaboration with a very rich research network exists amongst institutions in Asian, European and America countries. China and USA are ranked 1st and 2nd on countries based on productivity, publishing 30% and 21.7% of the total articles respectively. South Africa was the only African country found in the category of countries based on productivity occupying the 17th position. The spectacular growth of research by researchers domiciled in China suggests the dominance of China in scientific research. This study suggests high research interest on this class of pollutant in developed countries. Additionally, lack of funds and sophisticated analytical tools may be responsible for lack of PBDEs-related studies in developing countries especially in Africa.
    Keywords:  Analytical chemistry; Environmental science; Organic chemistry
    DOI:  https://doi.org/10.1016/j.heliyon.2018.e00964
  20. Oncol Nurs Forum. 2019 Jan 13. 46(1): 9-10
      I remember those halcyon days so well. I was the newly appointed editor of this esteemed journal, and the Oncology Nursing Forum (ONF) sat atop the impact factor list of nursing and allied health journals. As a reminder, the impact factor is a measure of the frequency with which the average article has been cited within a particular year. The latest impact factor from 2017 uses citation data from articles published from 2015-2016. To be clear, this is not a measure or commentary of an article's quality, but rather a journal's citation popularity among authors.
    Keywords:  communication; impact factor; membership benefit; nonprofit; nursing journals; open-access publication
    DOI:  https://doi.org/10.1188/19.ONF.9-10
  21. J Relig Health. 2018 Dec 06.
      This research aims to present a bibliometric analysis of the published documents on spirituality, religion and health. Despite the increasing number of publications spirituality, religion and health research in recent years, there is still little information about the effects of these publications in the literature. "Religion," "spirituality," "spiritual," "health" and "medicine" keywords were used to search the Web of Science (WoS) database. Bibliometric analysis was conducted on the articles published between 1975 and 2017. The analysis was presented with network and density maps. The analysis also included the regression analysis to predict a number of publications in 2018. A total number of 1674 publications were found: 818 of these publications were articles. Of the 818 articles, 210 were religion, 198 were Public Environmental Occupational Health, 139 were Psychology, and 77 were performed in the field of Psychiatry. The most productive journal with 107 articles and 1129 citations was the Journal of Religion and Health. The USA (495; 60.5%) was the most productive country on spirituality, religion and health publications. The author who had the highest number of publications and citations was Koenig HG (33 publications; 4.03% and 1617 citations), the document who had the highest number of citations was Ellison CG and Levin JS (633 citations), and the author who had the highest number of citations in the references was Koenig HG, 2001, (126 citations). Duke Univ was the top institution in the number of publication (50 Article). This study will lead the researchers especially in terms of the important journals, active countries, authors, top-cited articles and current topics in spirituality, religion and health research.
    Keywords:  Bibliometrics; Health; Medicine; Religion; Spirituality
    DOI:  https://doi.org/10.1007/s10943-018-00739-w
  22. Physiother Res Int. 2018 Dec 10. e1760
      OBJECTIVES: To undertake a bibliometric analysis of the physiotherapy literature at two points in time to identify similarities, differences, and the evolution of scholarship over a 40-year time-frame.METHOD: To undertake a quantitative comparative analysis of the published and indexed scholarship literature contained within Scopus relating to physiotherapy over two 10-year time windows-1978-1987 and 2008-2017. The method used, bibliometrics, is capable of identifying the nature of scholarship, the key actors, and how the focus and methods used to conduct studies have changed. A specialized bibliographic analysis and visualization tool VosViewer (University of Leiden) was used to analyse the extracted results.
    RESULTS: There has been a more than 10-fold increase in the number of papers published across the two time-frames (3,384 from the 1978 to 1987 period and 38,434 from 2008 to 2017). The focus of publication has moved from a medical disease orientated approach to one more specifically looking at physiotherapy interventions aimed at addressing functional ability. In addition, a more diverse range of research approaches are being used as well as efforts to synthesize findings across multiple studies using systematic reviews and meta-analytical techniques. Authors now come from a much wider range of countries than they did 40 years ago, and they are more likely to be part of a large international collaborative research teams.
    CONCLUSIONS: This unique and comprehensive analysis of physiotherapy scholarship across two different timeframes has provided important insights into the evolution of the profession, its changing focus and methodological approaches as well as the dramatic increase in activity, growth in research teams and diversity of country origins. For anyone entering the profession at this time, it provides a perspective on the pace of change they are likely to experience in their career ahead.
    Keywords:  Bibliometrics; physical therapist; publication; research
    DOI:  https://doi.org/10.1002/pri.1760
  23. Scientometrics. 2018 ;117(3): 1695-1719
      Biographical articles in scientific journals offer a platform for the commemoration of distinguished individuals from the world of science. Despite so important a role for the scientific community, research on biographical articles is scarce. To fill this gap, we have analyzed 190,350 biographical articles indexed in Web of Science, written by 251,908 authors in 1945-2014. We have analyzed the development of this article type over the studied period and research areas, how women and men are represented in the subject of articles, and who the authors are. Over the time the number of biographical articles has been increasing, with the highest number in Life Sciences and Biomedicine. Around 20% of the articles were written about women, with the highest share of 24% in Arts and Humanities. Both male and female authors write more often about men than about women, a stable situation for the last 70 years.
    Keywords:  Authors; Biographical articles; Citations; Document type; Gender; GenderizeR
    DOI:  https://doi.org/10.1007/s11192-018-2923-3
  24. J Neurointerv Surg. 2018 Dec 11. pii: neurintsurg-2018-014368. [Epub ahead of print]
      BACKGROUND AND PURPOSE: Alternative metrics (altmetrics), based on mentions in online media, is a new tool that can help to identify the most influential articles to diverse public audiences. This article aimed to determine the 100 most mentioned articles in the field of neurointervention and to analyze their characteristics.MATERIALS AND METHODS: We selected the 808 journals that were considered journals potentially publishing articles on neurointervention. We also selected articles using keywords. Using the Altmetric.com search tool, we identified the 101 most mentioned neurointervention articles based on the highest altmetric attention scores (AASs) within selected journals and articles. Each article was evaluated for several characteristics including AAS, number of citations, journal title, journal category, impact factor of the journal, year of publication, authorship, country, type of document, and topic.
    RESULTS: The AASs for the top 101 articles ranged from 1586 to 39. Stroke published the largest number of articles (19.8%) followed by the New England Journal of Medicine (17.8%). The majority of articles were published in multidisciplinary journals (38.6%), were published in 2017-2018 (43.6%), originated from the USA (54.5%), were original articles (66.3%), and dealt with intra-arterial thrombolysis or thrombectomy for acute ischemic stroke (58.4%). Tudor G Jovin was the most prolific author, authoring 18 of the most mentioned neurointervention articles CONCLUSIONS: This study presents a detailed list of the 101 most mentioned neurointervention articles in online media, thus providing useful information on the dissemination of neurointervention research to the general public.
    Keywords:  history; thrombectomy
    DOI:  https://doi.org/10.1136/neurintsurg-2018-014368
  25. Chin Med J (Engl). 2018 Dec 20. 131(24): 2968-2975
      Background: Macrophage polarization is involved in the development of many diseases such as obesity, diabetes, and cancer. This study aimed to understand the trends and hotspots of macrophage polarization research.Methods: We searched through the Web of Science Core Collection database to obtain original articles in this research domain. CiteSpace, HistCite, and VOSviewer software were used to facilitate the analysis and visualization of scientific productivity and emerging trends.
    Results: The survey included 3064 articles, and the annual number of publications exhibited an exponential increase. These articles have received a total of 74,801 citations, and the number of annual citations grew from 68 to 18,074 in a decade. Research on macrophage polarization was performed in 76 countries, and the USA ranked first in terms of research output by contributing 1129 (36.8%) articles. The USA also had the highest H-index, total citations, and highly cited article number. PLOS One, Journal of Immunology, and Scientific Reports were the three journals that published the most articles. Interdisciplinary research areas involving macrophage polarization, such as biomaterials, cancer, and diabetes, were identified by journal citation analysis. The top 20 most productive institutions were located mainly in the USA, France, and China, and top authors originated mainly from the USA and Italy. Tumor biology, obesity, and infection were research hotspots and may be promising in the next few years.
    Conclusions: This study provides a comprehensive analysis that delineates the scientific productivity, collaboration, and research hotspots of macrophage polarization research.
    Keywords:  Bibliometric Analysis; Macrophage; Macrophage Polarization
    DOI:  https://doi.org/10.4103/0366-6999.247215
  26. World Neurosurg. 2018 Dec 05. pii: S1878-8750(18)32764-5. [Epub ahead of print]
      OBJECTIVE: Management of odontoid fractures has improved and evolved due to advancing diagnostic guidelines and understanding of long-term outcomes. The aim of this study was to quantify the most frequently cited publications pertaining to odontoid fractures and determine their validity as a tool to practice evidence-based medicine.METHODS: A Clarivate Analytics Web of Science search was used to identify all articles related to odontoid fractures. The fifty most cited articles were reviewed. Criteria included the frequency of citation, year of publication, countries of origin, journal, levels-of-evidence (LOE), article types, and supporting authors and institutions.
    RESULTS: The top 3 most cited papers were "Radiological and anatomical evaluation of the atlantoaxial transarticular screw fixation technique" (Madawi 1997), "Atlantoaxial fixation using, plate and screw method: A report of 160 treated patients" (Goel 2002), and "The anatomical suitability of the C1-2 complex for transarticular screw fixation" (Paramore 1996). Spine (n=13; 26%) was the most common journal, and the most frequent decade was 2000-2009 (n=18; 36%). The United States was associated with the greatest number of publications, and the most common article type was Clinical Outcomes (n=16; 32%). The most recurring LOE was IV (n=20; 40%).
    CONCLUSIONS: This review provides a comprehensive understanding of the historical literature pertaining to odontoid fracture management. There is a paucity of high LOE publications regarding this topic, and clinicians should strive to provide more high-level studies. This article can help practitioners navigate the vast body of literature about this topic and identify high impact publications.
    Keywords:  Odontoid fracture; bibliometric study; citation analysis; elderly fracture management; most influential; odontoid
    DOI:  https://doi.org/10.1016/j.wneu.2018.11.205
  27. eNeurologicalSci. 2018 Dec;13 40-45
      Background: The Arab world has an increasing prevalence of strokes, a leading cause of death in this part of the world.Aims: The aim of this article is to quantify the stroke research activity in the Arab countries over the past 15 years taking into consideration the population, GDP, and DALY of each country.
    Methods: A PubMed search was conducted to find stroke research articles published from the Arab countries between 2002 and 2016 (inclusive). Medical subject headings related to strokes and author origin/affiliation were used for this purpose.
    Results: The Arab world only produced 0.51% of all the stroke-related publications on PubMed even though the stroke-related DALY percentage in this region was greater than 2.88% during the period we studied. In general, the number of publications increased in the last few years. Somalia came first regarding the percentage of stroke to non-stroke publications released. Lebanon had the highest number of publications per GDP (in US Billion Dollars), Qatar had the highest number of publications per million persons (PPMP), while Saudi Arabia had the highest number of publications per 1% of stroke DALY. In addition, a strong positive correlation was found between the number of stroke publications and GDP; however, the correlation between the number of stroke publication and either population size or DALY was a weak positive one.
    Conclusions: A general increase in publications is noticed, but stroke research activity in the Arab world is still poor compared to other parts of the world.
    Keywords:  Arab world; Bibliometric; DALY; GDP; Population; Stroke
    DOI:  https://doi.org/10.1016/j.ensci.2018.11.010
  28. BMC Infect Dis. 2018 Dec 10. 18(1): 639
      BACKGROUND: Lassa fever has been a public health concern in the West African sub-region where it is endemic and a latent threat to the world at large. We investigated the trend in Lassa fever research using bibliometric approach.METHODS: We used the SCOPUS database employing "Lassa fever" as search descriptor. The most common bibliometric indicators were applied for the selected publications.
    RESULTS: The number of scientific research articles retrieved for Lassa fever research from 1970 to 2017 was 1101. The growth of publications was more linear (r = 0.67) than exponential (r = 0.53). The duplication time of the scientific articles was 9.19 years. Small number of authors were responsible for bulk of the article production (transience index of 78.89%). The collaboration index was 4.59 per paper. The Bradford core consisted of 19 journals in which Journal of Virology was at the top (4.6%). Majority of the output were from USA government agencies. United States was the most productive country. Joseph B. McCormick was the most productive author, while New England Journal of Medicine published the two most cited articles.
    CONCLUSION: The growth of scientific Literature on Lassa fever was of linear pattern with high transient authors indicating low productivity and non-specialized authors from other related areas publishing sporadically. This study provides a helpful reference for medical virologists, epidemiologist, policy decision makers, academics and Lassa fever researchers.
    Keywords:  Bibliometric analysis; Lassa; Lassa fever; Lassa research
    DOI:  https://doi.org/10.1186/s12879-018-3526-6
  29. Urology. 2018 Dec 04. pii: S0090-4295(18)31269-X. [Epub ahead of print]
      OBJECTIVES: To determine what factors of published urology research articles are associated with future citations.METHODS: We identified all primary research articles published between 1997-2007 in Journal of Urology, British Journal of Urology International, Urology, and European Urology. Only 50 articles in this period had accrued 0 or 1 citation in a 10-year period following publication. We compared the characteristics of the articles in the low citation cohort to the 50 articles with the highest number of citations from the same journals and time period. Student's t-tests, Wilcoxon rank-sum tests, chi squared tests, and Fisher's exact tests were used to analyze the data with predetermined level of significance set to p<0.05.
    RESULTS: There were many significant differences between the two cohorts. When compared to the cohort of articles with 0 or 1 citation, highly cited articles were significantly more likely to be a clinical study, multi-institutional and multi-national effort, and related to the field of urologic oncology. They were also significantly more likely to have a larger sample size, a statistically significant primary finding, more authors, more references, and more tables, as well as longer title, abstract, and overall manuscript word counts.
    CONCLUSIONS: Very few articles published in the major urology journals accrued 0 or 1 citation over a 10-year period. This suggests that the vast majority of articles selected for publication are used to further future research. Nevertheless, there were distinct differences between the two cohorts, showing that certain factors are associated with articles being cited more frequently.
    Keywords:  Authorship; bibliometrics; citations; publishing; urology
    DOI:  https://doi.org/10.1016/j.urology.2018.11.034
  30. Isr J Health Policy Res. 2018 Dec 14. 7(1): 72
      The Israel Journal of Health Policy Research (IJHPR) was launched in 2012, with a mission that included fostering intensive intellectual interactions among health policy scholars in Israel and abroad. Now, as the journal approaches the end of its seventh year of publication, we can all be proud that this component of our mission is increasingly being realized.As of the end of November 2018, the Web of Science included 404 articles published by the IJHPR. These IJHPR articles had generated 1023 citations via 847 citing articles. Just over 70% of those citing articles were in journals other than the IJHPR, with the vast majority of those being in non-Israeli journals. The authors of the citing articles were most often based in institutions in the US (35%), Israel (33%), England (9%) or Canada (7%).Looking to the future, we hope that the IJHPR will receive even more submissions from authors based in Israel or other countries that are well-designed data-based studies; thoughtful, comprehensive policy analyses; or important integrations of a body of knowledge. In all instances, these should be relevant to Israeli health policy and health care. We hope that many, ideally most, will also be relevant to scholars, policymakers and professionals in other countries.
    DOI:  https://doi.org/10.1186/s13584-018-0269-1
  31. Acta Ortop Mex. 2018 Jul-Aug;32(4):32(4): 214-224
      BACKGROUND: The amount of quotation a scientific article receives is important for the academic impact. In the present study, we analyzed the 50 most cited articles in orthopedics and related areas published by mexican authors, as well as analyzing their main characteristics.MATERIAL AND METHODS: A search was conducted using Web of Science, of the 50 articles with the largest number of quotation on orthopedics and related areas, in which the principal author or corresponding author had an address in Mexico. We analyzed the articles of 66 scientific journals within the category Orthopedics. We examined the quantity and density of citations, Origin institution, subspeciality to which the article corresponds, and level of evidence.
    RESULTS: The most cited article had 222 cites. The 50 most cited articles accumulated a total of 1,944, with an average of 3.6 cites per year per article. The year with the largest number of publications was the 2011, and the year with the largest number of quotation was 2008. Public institutions had a larger number of publications in relation to private institutions. The subspecialty with the largest number of publications was arthroscopy and sport medicine. Most publications with a large number of citations refer to studies with a low level of evidence.
    CONCLUSIONS: The present study points out the 50 most cited articles published by mexican authors in orthopedics and related areas. There is a tendency towards publishing articles on some subspecialities, in particular on arthroscopy and sport medicine. Most publications have a low level of evidence.
    Keywords:  Orthopedic literature; bibliometric analysis; cites; impact factor; mexican authors; orthopedics
  32. Rev Med Chil. 2018 Aug;pii: S0034-98872018000800913. [Epub ahead of print]146(8): 913-920
      Medical journals are fundamental elements in medical education, in professional life, in research and in academic careers. They communicate new scientific and clinical findings, legitimate and give credibility to biomedical and clinical investigation, are guarantors of the authors' intellectual property, are a useful forum for the discussion of relevant topics, distribute selected information to readers and are archives of their publications. Out of the numerous medical journals appeared before and during the XIXth Century, only 24 of them remain active until today and Revista Médica de Chile appears as number 20 in the list. Nowadays thousands of medical journals are published worldwide but only a small fraction are qualified as "mainstream journals", because they strictly apply an independent editorial process with clear criteria in manuscript selection based in external peer review, format requisites according to ICMJE Recommendations, are included in major databases, publish a high proportion of research articles, and other reasons. English language predominates in mainstream journals and abstracts in English become available in some databases. Electronic publications and open access are important tools to disseminate new information but the appearance of "predatory journals" is a threatening menace to the integrity of medical publications. Authors should identify and reject them. Some reflections may help those who intend to create new medical journals.
    DOI:  https://doi.org/10.4067/s0034-98872018000800913
  33. Cir Esp. 2018 Dec 11. pii: S0009-739X(18)30297-5. [Epub ahead of print]
      INTRODUCTION: We performed a study of the top 100 most cited articles in the five general surgery journals with the highest impact according to Journal Citation Report.METHODS: We selected the five journals with the highest impact in 2015: Annals of Surgery, British Journal of Surgery, JAMA Surgery, Surgery, and Journal of the American College of Surgeons. In January 2017, using the Web of Science application, we performed a search of all articles published by these journals and identified the 100 most cited articles (top 100). We evaluated the number of citations, year of publication, type of article, country and hospital of the article, area of interest and number of authors.
    RESULTS: The median number of citations per top 100 paper was 490. Twenty percent of the top 100 papers have been published since 2000. Overall, 70% are original papers, 8% randomized control trials, 11% reviews, 1% meta-analyses and 11% other subtypes. There are 13% proceedings papers. Sixty-one percent are from the US. The most frequently discussed topic is hepato-pancreato-biliary surgery (33%).
    CONCLUSIONS: The top 100 most cited articles tend to be original articles describing studies carried out in the US, reporting significant surgical breakthroughs. Hepato-pancreato-biliary surgery is the most common subject area. Annals of Surgery had twice as many citations as the other journals studied. The archetypal article of the Top15 most cited is an original paper published in the twentieth century, with an average of 2000 citations.
    Keywords:  Artículo científico; Bibliometrics; Bibliometría; Cirugía; Citación; Citation; Factor de impacto; Journal article; Journal impact factor; Surgery
    DOI:  https://doi.org/10.1016/j.ciresp.2018.10.013
  34. BMC Proc. 2018 ;12(Suppl 10): 18
      Background and purpose: Dissemination of research results is a key component of the research continuum and is commonly achieved through publication in peer-reviewed academic journals. However, issues of poor quality reporting in the research literature are well documented. A lack of formal training in journalology (i.e., publication science) may contribute to this problem. To help address this gap in training, the Enhancing the QUAlity and Transparency Of health Research (EQUATOR) Canada Publication School was developed and facilitated by internationally-renowned faculty to train researchers and clinicians in reporting and publication best practices. This article describes the structure of the inaugural course and provides an overview of attendee evaluations and perspectives.Key highlights: Attendees perceived the content of this two-day intensive course as highly informative. They noted that the course helped them learn skills that were relevant to academic publishing (e.g., using reporting guidelines in all phases of the research process; using scholarly metrics beyond the journal impact factor; open-access publication models; and engaging patients in the research process). The course provided an opportunity for researchers to share their challenges faced during the publication process and to learn skills for improving reproducibility, completeness, transparency, and dissemination of research results. There was some suggestion that this type of course should be offered and integrated into formal training and course curricula.
    Implications: In light of the importance of academic publishing in the scientific process, there is a need to train and prepare researchers with skills in Journalology. The EQUATOR Canada Publication School provides an example of a successful program that addressed the needs of researchers across career trajectories and provided them with resources to be successful in the publication process. This approach can be used, modified, and/or adapted by curriculum developers interested in designing similar programs, and could be incorporated into academic and clinical research training programs.
    Keywords:  Medical education; Publication science; Reporting quality; Scholarly communications
    DOI:  https://doi.org/10.1186/s12919-018-0155-4
  35. Clin Respir J. 2018 Dec 10.
      INTRODUCTION: Respiratory disease remains one of the leading causes of mortality and morbidity worldwide.OBJECTIVES: In this study, we aimed to compare the quantity and quality of scientific publications in the field of respirology from the USA, the UK, Germany, Canada and China.
    METHODS: Articles published in 58 respiratory journals from 2007 to 2017 were screened with Science Citation Index Expanded database. The number of total and annual articles, article types, impact factor (IF), h-index, citations and articles in the high-impact journals from the corresponding country were collected for quantity and quality comparisons. The correlation of socioeconomic factors and annual publications was also analyzed.
    RESULTS: A total of 93078 articles were published worldwide in respiratory journals from 2007 to 2017. The USA contributed the largest proportion (34399 (37.0%)), followed by the UK (9494 (10.2%)), Germany (6918 (7.4%)) and Canada (6574 (7.1%)). Publications from China represented the sixth, but this quantity is rapidly increasing. The USA occupies the dominant place in all kinds of article types under investigation in the study, except in the category of meta-analysis. For total and average citations, China still lags behind the other four countries in the study. The annual numbers of articles from China, Canada and the USA were positively correlated with gross domestic product (p<0.05).
    CONCLUSIONS: The USA has played predominant role in respiratory research for the last 11 years. Although China has made great progress in the number of published articles over the past decade, the quality of these publications needs further improvement. This article is protected by copyright. All rights reserved.
    Keywords:  Citations; H-index; Science Citation Index Expanded; impact factor; publications; respirology
    DOI:  https://doi.org/10.1111/crj.12980
  36. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2018 Oct 20. 36(10): 738-741
      Objective: To analyze the relevant literature on China's occupational health standard from 2001 to 2016, and to provide a basis for further improving China's occupational health standard system. Methods: Wanfang Data, CNKI, VIP, PubMed, Embase, and Web of Knowledge were used to retrieve relevant literature on China's occupational health standard from 2001 to 2016. Information of the literature was collected, and type of literature, time and region, first author's affiliation, and research funding were analyzed by bibliometrics. Results: The relevant literature on China's occupational health standard was concentrated domestically and in the health system, and the number of documents was highly correlated with socio-economic conditions. The literature was dominated by the research on onsite application of occupational health (53.08%) , while there was less research on occupational health standard (11.78%) . The number of published articles and funding intensity were significantly different between centers for disease control and prevention at different levels. Conclusion: It is suggested to accelerate the application of evidence-based medicine and systematic review in the development of occupational health standard, enhance the research ability of county/district-level disease control officers, assist them in summarizing and publishing their daily work experience, and give them appropriate funding, so as to promote the accumulation of knowledge in the field of occupational health.
    Keywords:  Bibliometric; Occupational health standard; Research literature
    DOI:  https://doi.org/10.3760/cma.j.issn.1001-9391.2018.10.004