Front Med (Lausanne). 2025 ;12 1477351
Purpose: This study analyzed the research trends in machine learning (ML) pertaining to myocardial infarction (MI) from 2008 to 2024, aiming to identify emerging trends and hotspots in the field, providing insights into the future directions of research and development in ML for MI. Additionally, it compared the contributions of various countries, authors, and agencies to the field of ML research focused on MI.
Method: A total of 1,036 publications were collected from the Web of Science Core Collection database. CiteSpace 6.3.R1, Bibliometrix, and VOSviewer were utilized to analyze bibliometric characteristics, determining the number of publications, countries, institutions, authors, keywords, and cited authors, documents, and journals in popular scientific fields. CiteSpace was used for temporal trend analysis, Bibliometrix for quantitative country and institutional analysis, and VOSviewer for visualization of collaboration networks.
Results: Since the emergence of research literature on medical imaging and machine learning (ML) in 2008, interest in this field has grown rapidly, particularly since the pivotal moment in 2016. The ML and MI domains, represented by China and the United States, have experienced swift development in research after 2015, albeit with the United States significantly outperforming China in research quality (as evidenced by the higher impact factors of journals and citation counts of publications from the United States). Institutional collaborations have formed, notably between Harvard Medical School in the United States and Capital Medical University in China, highlighting the need for enhanced cooperation among domestic and international institutions. In the realm of MI and ML research, cooperative teams led by figures such as Dey, Damini, and Berman, Daniel S. in the United States have emerged, indicating that Chinese scholars should strengthen their collaborations and focus on both qualitative and quantitative development. The overall direction of MI and ML research trends toward Medicine, Medical Sciences, Molecular Biology, and Genetics. In particular, publications in "Circulation" and "Computers in Biology and Medicine" from the United States hold prominent positions in this study.
Conclusion: This paper presents a comprehensive exploration of the research hotspots, trends, and future directions in the field of MI and ML over the past two decades. The analysis reveals that deep learning is an emerging research direction in MI, with neural networks playing a crucial role in early diagnosis, risk assessment, and rehabilitation therapy.
Keywords: CiteSpace; bibliometrics; deep learning; machine learning; myocardial infarction