bims-evares Biomed News
on Evaluation of research
Issue of 2025–06–01
84 papers selected by
Thomas Krichel, Open Library Society
  1. Spanish dermatologists' publications in top-tier journals: a bibliometric analysis (1950-2024).
  2. Research trends and hotspots of cognitive behavioral therapy for tinnitus: a bibliometric analysis.
  3. Research hotspots and future trends of insomnia in Parkinson's disease: a bibliometric and visualization analysis from 1973 to 2024.
  4. Research trends on lactate in cancer: a bibliometric analysis and comprehensive review (2015-2024).
  5. Bibliometric analysis and visualization of Connexin 43 in the field of solid tumor research(2000-2024).
  6. Research Trends in Vascular Aging in the Last Decade: A Comprehensive Bibliometric Analysis.
  7. Global trends and hotspots in artificial intelligence for high myopia: a bibliometric analysis.
  8. A bibliometric evaluation of scientific productivity in meibomian gland dysfunction research.
  9. Revealing the impact of teaching methods on anxiety among college students through a bibliometric study.
  10. Trends and Scientific Production on Isometric Training: A Bibliometric Analysis.
  11. Osseodensification in Oral Implantology: A Bibliometric Analysis.
  12. Bibliometric Analysis of Research Trends and Global Collaborations in Anesthesia on Neuromuscular Blockers and Antagonists (2000-2024).
  13. Trends and Emerging Research Areas in Postoperative Sleep Disturbances: A Bibliometric Analysis.
  14. Transcranial ultrasound stimulation in neuromodulation: a bibliometric analysis from 2004 to 2024.
  15. Bibliometrics Analysis and Knowledge Mapping of Fragment-Based Drug Design Research: Trends from 2015 to 2024.
  16. Research hotspots and trends in unexplained recurrent spontaneous abortion (URSA) from 2014 to 2024: a bibliometric analysis.
  17. Knowledge map of artificial intelligence in neurodegenerative diseases: a decade-long bibliometric and visualization study.
  18. Global trends and collaborations in bortezomib-induced neurotoxicity research: a bibliometric analysis (2002-2024).
  19. The evolution of FLASH radiotherapy: a bibliometric analysis.
  20. Mapping the Research Landscape of Cleft Lip and Palate Management: Insights From a Bibliometric Perspective.
  21. Global status and trends of invasive pulmonary aspergillosis: A bibliometric study.
  22. A bibliometric review and visualization of research on myocardial ischemia/reperfusion injury in patients with diabetes mellitus from 2004 to 2024.
  23. A bibliometric analysis of chronic kidney disease-associated pruritus from 2004 to 2023.
  24. Global research trends on exercise and circadian rhythm: A bibliometric analysis.
  25. Exploring the use of traditional Chinese medicine exercises for cancer patients from the perspective of bibliometrics.
  26. The use of ultrasonography in dentistry: a bibliometric analysis.
  27. Female authorship trends in high-impact spine surgery journals.
  28. Photodynamic Therapy in Ocular Oncology: A Bibliometric Analysis (1987-2024).
  29. A comprehensive bibliometric analysis of ferroptosis in tumor resistance: development and emerging trends.
  30. Global research on the utilization of population pharmacokinetic model: a bibliometric analysis from 2000 to 2024.
  31. Critical Care Echocardiography: A Bibliometric Analysis of Knowledge Structure and Evolution of Development Trends From 2005 to 2024.
  32. Osseointegration of Dental Implants in Irradiated Patients: A Bibliometric Study.
  33. Tracing the history of clinical practice of liquid biopsy: a bibliometric analysis.
  34. Research trends and hotspots of circulating tumor DNA in colorectal cancer: a bibliometric study.
  35. Intense Pulsed Light for the Treatment of Dry Eye Disease: A Bibliometric and Visualized Analysis.
  36. Bibliometric analysis of research trends on the combination of radiotherapy and PARP inhibitors in solid tumors.
  37. The role of autophagy in periodontal diseases: a bibliometric analysis from 2006 to 2023.
  38. Pediatric Orthopaedic Studies Published Open Access are Associated with Increased Citation Rates.
  39. Global research trends on endoplasmic reticulum stress in retinal diseases from 2000 to 2024.
  40. Bibliometric Analysis of The Global Research Trends on The Application of Tamoxifen in The Treatment of Breast Cancer Over The Past 50 Years.
  41. A Bibliometric Analysis of Medication Compliance in Children with Asthma.
  42. Beyond citations: exploring gender and racial gaps in urology publications through citation and Altmetric analysis.
  43. Global Trends and Hot Topics in Nursing Studies on Immigrants: A Retrospective Bibliometric Analysis From 1975 to 2024.
  44. Nutritional composition and health benefits of peas-a bibliometric research.
  45. The present and future of geriatric internal medicine: a bibliometric analysis.
  46. Visualized bibliometric panorama of ureteral stents (1975-present): trends and hotspots revealed.
  47. Compassion fatigue in laboratory animal personnel: a bibliometric analysis of global trends.
  48. A scientometric analysis of machine learning in schizophrenia neuroimaging: Trends and insights (2012-2024).
  49. Global research trends on the links between prostate cancer and postoperative urinary incontinence between 2014 and 2024: a bibliometrics and visualized study.
  50. Disclosing the development and focus of sequencing and omics studies in kidney neoplasm research.
  51. Global trends and hotspots in nutritional risk screening, assessment, and diagnosis: A bibliometric and visual analysis (1991-2024).
  52. Analysis of article types of the top-100 cited articles on gastrointestinal endoscopy.
  53. Global Trends in the Use of Artificial Intelligence in Dental Education: A Bibliometric Analysis.
  54. Data-Driven Visualization of the Dynamics of Antimicrobial Peptides in Cell Death.
  55. Chemotherapy cardiotoxicity research in cancer patients: a bibliometric and visual analysis (1994-2024).
  56. Mapping Research Trends on the Implications of Telemedicine for Healthcare Professionals: A Comprehensive Bibliometric Analysis.
  57. Microorganisms in Macroalgae Cultivation Ecosystems: A Systematic Review and Future Prospects Based on Bibliometric Analysis.
  58. Authorship Inequity in Global Health Research Conducted in Low- and Middle-Income Countries and Published in High-Income Country Family Medicine Journals.
  59. Connecting urban green and blue spaces with children' health: a bibliometric analysis in CiteSpace and VOSviewer.
  60. Letter to the Editor Regarding: Cerebrospinal Fluid Biomarkers in Idiopathic Normal Pressure Hydrocephalus: Bibliometric Analysis and Literature Review.
  61. Mapping Artificial Intelligence Research Trends in Critical Care Nursing: A Bibliometric Analysis.
  62. Household dysfunction and child outcomes in the Nordic countries: A bibliometric analysis.
  63. How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?
  64. Research landscape and trends of human umbilical cord mesenchymal stem cell-derived exosomes.
  65. Machine Learning and Artificial Intelligence in Suicide Prevention: A Bibliometric Analysis of Emerging Trends and Implications for Nursing.
  66. Progress analysis of multi-dimensional perspective research on green ships: A knowledge graph-based approach.
  67. Vaccine Research Trends in Africa from 2016 to Mid-2024: A Bibliometric Analysis.
  68. Visual Research of Global Orphan Drug from a Bibliometric Perspective.
  69. How COVID-19 affected academic publishing: a 3-year study of 17 million research papers.
  70. Unlocking the potential of fish protein hydrolysates: Bioactive and technofunctional properties, applications, challenges, and future perspectives.
  71. Valsci: an open-source, self-hostable literature review utility for automated large-batch scientific claim verification using large language models.
  72. Application of Biologics in the Treatment of Asthma in the Past Two Decades: A Bibliometric Analysis and Beyond.
  73. Sustainability Awareness in Manufacturing: A Review of IoT Audio Sensor Applications in the Industry 5.0 Era.
  74. False authorship: an explorative case study around an AI-generated article published under my name.
  75. Exploring the meaning of home for the older adults: A bibliometric analysis of environmental and psychological needs (1969-2023).
  76. The 'pivot penalty': scientists get cited less after switching fields, analysis finds.
  77. The dynamic linkage between covid-19 and nutrition: a review from a probiotics perspective using machine learning and bibliometric analysis.
  78. Message from the New Editor-in-Chief: Continuity and Change, Impact and Visibility.
  79. Uncovering Novel Anti-Lung Cancer Compounds: Insights from Marine Sponge-Derived Agents: A Bibliometric Review.
  80. Negotiating science funding: The interplay of merit, bias, and administrative discretion in grant allocation in Kazakhstan.
  81. The challenges of indexing and impact factor in Latin American cardiology journals.
  82. A Comprehensive Literature Review for Total Hip Arthroplasty (THA): Part 2-Material Selection Criteria and Methods.
  83. Bibliometric analyses of factors influencing color preferences in urban environmental spaces.
  84. The pivot penalty in research.
  1. Actas Dermosifiliogr. 2025 May 22. pii: S0001-7310(25)00361-8. [Epub ahead of print]
    Spanish dermatologists' publications in top-tier journals: a bibliometric analysis (1950-2024).
    W Hassan, A E Duarte.
      
    DOI:  https://doi.org/10.1016/j.ad.2025.02.029
  2. Front Neurosci. 2025 ;19 1536224
    Research trends and hotspots of cognitive behavioral therapy for tinnitus: a bibliometric analysis.
    Yu He, Jiahui Liu, Hongmei Cheng, Hongkun Ye, Chongrui Li, Yahan Gao, Xinyin Xu.
       Background: Tinnitus, defined as the perception of sound without an external auditory stimulus, affects millions worldwide, significantly diminishing their quality of life. Cognitive behavioral therapy (CBT) is the most evidence-based treatment for tinnitus management, proven effective in reducing tinnitus-related distress and severity. This study aims to evaluate the current status, emerging trends, and research hotspots in CBT for tinnitus using bibliometric methods, offering valuable insights for future studies in this field.
    Methods: Publications related to CBT for tinnitus were retrieved from the Web of Science Core Collection (WoSCC) database from 1985 to 2024. Bibliometric analysis and visualization were performed using VOSviewer, CiteSpace, and the R package "bibliometrix."
    Results: A total of 209 publications were included in this study. Research on CBT for tinnitus has shown a steady upward trend. Sweden, the United Kingdom and the United States have made notable contributions to this field. Linköping University and Karolinska Institute are the leading research institutions. Gerhard Andersson is the most prolific author and ranks first in citation frequency. The most prolific journal is the American Journal of Audiology, while Ear and Hearing is the most frequently co-cited journal. The highly cited references primarily encompass clinical trials, systematic reviews, and meta-analyses that focus on cognitive-behavioral therapy interventions. Recent keyword trends highlight topics such as "mindfulness," "acceptance and commitment therapy," and "internet-based interventions." Addressing psychological comorbidities of tinnitus, including depression and anxiety, is identified as a future research focus.
    Conclusion: This bibliometric analysis provides a comprehensive overview of the research landscape for CBT in tinnitus management. Current research emphasizes various CBT modalities to treat psychological comorbidities associated with tinnitus. Future studies should prioritize high-quality research to confirm the long-term efficacy of CBT in tinnitus management.
    Keywords:  bibliometric analysis; cognitive behavioral therapy; hotspots; tinnitus; trends
    DOI:  https://doi.org/10.3389/fnins.2025.1536224
  3. Front Aging Neurosci. 2025 ;17 1535861
    Research hotspots and future trends of insomnia in Parkinson's disease: a bibliometric and visualization analysis from 1973 to 2024.
    Xianghong Guo, Tianye Wang, Dan Wang, Jingjing Zhou, Xin Lai.
      Background and objectives: Despite the growing body of research on Parkinson's disease (PD) and insomnia, comprehensive analysis of overall research trends remains limited. This study aims to evaluate these trends and identify research hot spots using bibliometric analysis.
    Methods: Publications on PD and insomnia from 1973 to 2024 were extracted from the Web of Science Core Collection. Analytical tools such as VOSviewer, CiteSpace, and R 4.3.3 were employed for evaluation.
    Results: A total of 610 publications are analyzed, demonstrating a consistent upward trend. The United States leads the field with 150 articles, representing 24.59% of total output, followed by China with 79 publications. Harvard University is the top contributing institution with 44 articles. Movement Disorders ranks as the leading journal, publishing 28 papers (4.59% of the total) and also securing the top spot in total citations. The most prolific author is Lima Marcelo M. S., with 15 publications and 50 recorded collaborations. Burst keyword analysis revealed increasing interest in terms such as "validation," "index," and "scale" since 2019.
    Conclusion: Research on PD and insomnia exhibits a clear upward trend, reflecting increasing academic interest. Future studies are expected to focus on the validation of diagnostic tools, the development of scales, and the integration of artificial intelligence and personalized medicine for improved treatment precision.
    Keywords:  CiteSpace; Parkinson’s disease; VOSviewer; bibliometric analysis; insomnia
    DOI:  https://doi.org/10.3389/fnagi.2025.1535861
  4. Front Immunol. 2025 ;16 1587867
    Research trends on lactate in cancer: a bibliometric analysis and comprehensive review (2015-2024).
    Sinong Li, Ziyi Yang, Mutian Lv, Lin Zong, Yihan Xie, Zoujuan Cai, Ying Zhang, Zhongqing Wang, Zhe Liu, Liang Sang.
       Objective: A bibliometric approach was employed to systematically analyze the trends and potential future developments in lactic acid-related cancer research over the past 10 years.
    Method: We conducted a bibliometric analysis of literature on lactic acid in cancer research from 2015 to 2024, using data collected from the Web of Science database. A bibliometric analysis was conducted to identify general research directions and trends in current publications, as well as to determine the most prolific and influential authors, institutions, countries, and keywords in lactate and cancer research. The data were collected and analyzed using VOSviewer (Leiden University, Leiden, Netherlands), Microsoft Excel (Microsoft, Redmond, Washington, USA), CiteSpace, and Biblioshiny, with a focus on analysis and visualization.
    Results: A total of 5,999 publications were analyzed, focusing on various aspects of the relevant literature, including year of publication, country, institution, author, journal, category, keywords, and research frontiers. The analysis of these publications reveals a general upward trend in publication volume from 2015 to 2024, with China and University of California System emerging as the most prolific country and institution, respectively. SCIENTIFIC REPORTS is the most frequently published journal, while Oncotarget is the most cited journal in the field. Zhang Y. was the most prolific author, publishing 100 documents over 10 years, with the highest citation count and an H-index of 28.Keyword analysis revealed five key themes in lactate-cancer research (2013-2023): Metabolic-epigenetic crosstalk, Tumor immunosuppressive microenvironment, Innovative therapies/drug delivery, Lactate-mediated signaling, Metabolic-targeted treatment strategies. Current research emphasizes the application of lactic acid metabolism in metabolic intervention, immune microenvironment regulation, combination of new therapeutic techniques and applications in specific cancer types.
    Conclusion: Research on lactic acid in cancer is growing rapidly, with China at the forefront of this field. Research into lactic acid's role in immune cell regulation, metabolism, and signaling pathways, combined with multi-modal imaging, big data analytics, and innovative drug delivery, is set to become a key trend in future studies, which promises new directions for identifying therapeutic targets, biomarkers, and developing advanced treatments.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; cancer; lactic acid
    DOI:  https://doi.org/10.3389/fimmu.2025.1587867
  5. Front Immunol. 2025 ;16 1588828
    Bibliometric analysis and visualization of Connexin 43 in the field of solid tumor research(2000-2024).
    Caiqi Huang, Xiaoman Liu, Yanhui Feng, Zhesi Xiao, Zhengjia Lu, Lu Wang, Jia Ming.
       Background: Connexin 43 (Cx43) plays a pivotal role in tumor growth, metastasis, and disease progression. This study employs bibliometric analysis to identify key research trends and emerging hotspots in Cx43-related solid tumor research.
    Methods: In December 2024, the Web of Science Core Collection (WoSCC) database was searched for publications on Cx43 in solid tumor research from 2000 to 2024. Bibliometric analysis and data visualization were primarily conducted using CiteSpace, VOSviewer, and Bibliometrix, with a focus on visualizing aspects such as countries, institutions, journals, authors, references, and keywords in the field.
    Results: A total of 1,666 publications were retrieved, with the annual number of articles and citations continuing to grow. The United States and China had the highest number of publications, while the University of Western Ontario in Canada was the leading institution, with the most publications by Christian C.G. Nau. Lampe, P.D. was the most cited author. The International Journal of Molecular Sciences was the most frequently published journal, and the Journal of Biological Chemistry was the most frequently co-cited journal. High-frequency keywords included phosphorylation, breast cancer, gastric cancer, prognostic markers, anti-tumor immune response, and drug resistance.
    Conclusion: Contemporary research focuses on the role of Cx43 phosphorylation in tumorigenesis, progression, and metastasis, its potential as a prognostic biomarker, and its critical role as an immunotherapeutic target and in tumor drug resistance. These studies provide a comprehensive analysis for a deeper understanding of the role of Cx43 in solid tumors and help to promote further research in this area.
    Keywords:  Cx43; bibliometric analysis; immunity; phosphorylation; prognostic signature; resistance; solid tumor
    DOI:  https://doi.org/10.3389/fimmu.2025.1588828
  6. Vasc Health Risk Manag. 2025 ;21 411-423
    Research Trends in Vascular Aging in the Last Decade: A Comprehensive Bibliometric Analysis.
    Dandan Shi, Ziqi Ning, Yaoyao Zhang, Xiaochen Guo, Yun Wei, Meixia Liu.
       Background: In recent years, vascular aging has emerged as a hot topic in become an important direction of aging research, but a comprehensive bibliometric analysis has not been conducted.
    Methods: The Web of Science database was searched for articles and reviews on vascular aging from January 1, 2014, to August 20, 2024, and the literature was analyzed and knowledge maps were constructed using CiteSpace, VOSviewer, pajek and Scimago Graphica software for econometric analysis and knowledge graph construction of the literature.
    Results: A total of 38,910 authors from 7622 institutions in 111 countries published 7277 papers in 1344 academic journals, with a significant increase in publication volume. The United States is the country with the highest productivity and citation rates, and Mayo Clinic is the most active institution. Tarantini S published the most papers, while Csiszar A received the most citations. Retina-The Journal of Retinal and Vitreous Diseases journal published the most papers, and Circulation journal received the most citations. The main research aspects include age-related macular degeneration, arteriosclerosis, and oxidative stress, which are the main keywords in this field. In the last decade, the term c reactive protein has attracted great attention with its strongest citation explosion.
    Conclusion: In the past decade, the research focus on vascular aging has been increasing year by year. Age-related macular degeneration, arteriosclerosis, oxidative stress and vascular endothelial cells are the emerging research directions in this field.
    Keywords:  bibliometric analysis; research trends; vascular aging; visual analysis
    DOI:  https://doi.org/10.2147/VHRM.S517302
  7. Front Med (Lausanne). 2025 ;12 1567440
    Global trends and hotspots in artificial intelligence for high myopia: a bibliometric analysis.
    Xuze Wang, Ailixiati Wumaier, Jun Wang, Dejuan Song, Yiting Cai, Jin Han, Wei Han, Zhi Fang.
       Purpose: This study aims to conduct a bibliometric analysis of global publications on the application of artificial intelligence (AI) in high myopia (HM).
    Methods: We retrieved publications on AI in HM from the Web of Science Core Collection (WoSCC) database, MEDLINE and Chinese Science Citation Database (CSCD) with data up to 2024. The analysis focused on publication and citation trends, identifying key articles, influential countries, institutions, authors, and journals. Additionally, we explored research domains and emerging keywords.
    Results: A total of 167 relevant publications were included. The first AI-related paper on HM was published in 2017, with a significant surge in 2021, followed by a consistent increase in publication and citation counts over the next 3 years. China emerged as the most productive country, with the most extensive international collaboration. East Asian authors dominated the top 10 most influential authors. Yang, Weihua and Investigative Ophthalmology & Visual Science (IOVS) contributed the most publications among authors and institutions, respectively. Keyword analysis revealed that retinal imaging-related terms remained a consistent research focus, while newly emerging keywords included "automated detection" and "childhood."
    Conclusion: Recent advancements in AI applications for HM have been significant and are expected to continue. Future research will likely focus on multimodal imaging and improving algorithm accessibility. Our findings offered the first comprehensive overview of global research on AI in HM, thus providing valuable insights for researchers to understand the current status and future trends in this field.
    Keywords:  artificial intelligence; bibliometric analysis; data visualization; global research; high myopia
    DOI:  https://doi.org/10.3389/fmed.2025.1567440
  8. Clin Exp Optom. 2025 May 26. 1-8
    A bibliometric evaluation of scientific productivity in meibomian gland dysfunction research.
    Bedia Kesimal, Sücattin İlker Kocamış.
       CLINICAL RELEVANCE: Meibomian gland dysfunction (MGD) is a major contributor to dry eye disease, affecting a large proportion of the population and leading to significant discomfort and ocular surface complications. Understanding trends in MGD research, including advancements in diagnostic technologies, therapeutic approaches, and interdisciplinary collaborations, is critical for improving clinical practices.
    BACKGROUND: This study aims to perform a bibliometric analysis on MGD to assess the current international status of meibomian gland dysfunction research and identify the most influential contributors (journals, countries, authors) and research topics in this field.
    METHODS: Data from studies on MGD were obtained using the Web of Science Core Collection on Science Citation Index Expanded database. Information regarding journals, titles, text, keywords, references, citations, author names, author institutions, and countries was recorded for each publication. The data were analysed using features of the Web of Science Core Collection website and the VOSviewer visualisation tool.
    RESULTS: A total of 1313 articles published between 1980 and 2024 were identified. The number of articles published in the last 10 years was found to be 3.01 times greater than in all previous years combined. The United States and China were the most productive countries, with the highest number of articles and citations. The most productive institutions were located in the United States and Japan. The most prolific author was Reiko Arita. The most frequently cited article was titled 'The International Workshop on Meibomian Gland Dysfunction: Report of the Subcommittee on Anatomy, Physiology, and Pathophysiology of the Meibomian Gland'. Recent and emerging keywords include 'intense pulsed light', 'meibography', 'lipiflow', 'artificial intelligence', 'meibogenesis', 'lipidomics' and 'human meibomian gland epithelium', reflecting current trends in MGD research.
    CONCLUSIONS: This study provides an overview of the current status and trends in MGD research, which may help clinicians and researchers better understand this field and predict its future directions.
    Keywords:  Bibliometric analysis; Science Citation Expanded; Web of Science; citation; meibomian gland dysfunction
    DOI:  https://doi.org/10.1080/08164622.2025.2507397
  9. Front Psychol. 2025 ;16 1558313
    Revealing the impact of teaching methods on anxiety among college students through a bibliometric study.
    Zhongzhu Ai, Dongfeng Yuan, Ruotong Dong, Yun Li, Shanshan Zhou.
       Objective: Anxiety has become increasingly prevalent among university students, significantly affecting their academic performance. Reforming teaching methods as a potential strategy to alleviate anxiety has garnered growing attention over the years. This study aims to systematically analyze and discuss the impact of teaching method reforms on college student anxiety.
    Methods: The Web of Science (WOS) database was used to retrieve and collect relevant literature from 2004 to 2024. Major publication sources, countries, institutions, and authors in this field were identified through the number of publications, citation frequency, and H-index indicators. Data-driven analysis was conducted to explore collaboration patterns, knowledge structures, research hotspots, and trends using VOSviewer software.
    Results: After screening, this study included 192 publications from January 2004 to November 2024, revealing several significant findings: (1) The number of publications has gradually increased, peaking in 2022 and maintaining a high level in the following years. (2) The most productive and influential journals are Nurse Education Today and CBE Life Sciences Education, with the USA and the Indiana University System contributing the most. (3) Collaboration network analysis indicates the presence of multiple research groups in the field, but their connections among countries and authors remain relatively limited. (4) Co-citation analysis of journals shows that the field is interdisciplinary, primarily merging psychology, education, and information technology. (5) Keyword analysis identifies two major research hotspots: factors influencing student anxiety in teaching environments (e.g., self-efficacy, loneliness, and performance) and the moderating effects of teaching method reforms (e.g., blended learning, collaborative learning, and experiential learning) on college student anxiety.
    Conclusion: This visualization analysis provides an overview of the directions and advancements in research on the impact of teaching method reforms on college students' anxiety. It offers a comprehensive examination of the latest frontiers and trends, contributing theoretical support to educational practices and mental health interventions.
    Keywords:  anxiety; bibliometric; college students; teaching methods; trending topics
    DOI:  https://doi.org/10.3389/fpsyg.2025.1558313
  10. Sports (Basel). 2025 May 12. pii: 145. [Epub ahead of print]13(5):
    Trends and Scientific Production on Isometric Training: A Bibliometric Analysis.
    Mario Ríos Riquelme, Ángel Denche-Zamorano, Diana Salas-Gómez, Antonio Castillo-Paredes, Gerson Ferrari, Cecilia Marín-Guajardo, Juan Francisco Loro-Ferrer.
      Isometric training is a method focused on muscle strengthening without joint movement and has gained attention in recent years due to its applicability in rehabilitation and sports medicine. However, no comprehensive bibliometric analysis focused exclusively on adult populations has been performed. This study aimed to analyze the scientific production related to isometric training in adults; identify prominent authors, journals, and thematic trends; and evaluate the evolution of interest in this field over time. A bibliometric review was performed using the Web of Science Core Collection (SCI-E, SSCI, and ESCI). A specific search strategy was applied to identify articles and reviews focused on isometric training in adult populations. A total of 238 records met the inclusion criteria. Data were analyzed using Excel 2016 and VOSviewer software1.6.20. Bibliometric indicators such as Price's Law, Bradford's Law, Lotka's Law, h-index, and co-occurrence and co-authorship network analysis were applied. The results showed a steady increase in publications in the last decade, highlighting the categories of Sports Science, Physiology, and Cardiovascular. The Journal of Applied Physiology was the most frequent source, and Springer Nature was the most prolific publisher. The h-index identified 21 highly cited papers, and Lotka's Law confirmed the existence of a small group of prolific authors. VOSviewer analysis revealed clear thematic clusters, mainly around blood pressure regulation, rehabilitation, and aging. International collaboration was evident, with the United States, Canada, and the United Kingdom leading the co-authorship networks. Scientific interest in isometric training for adult populations is growing, particularly in relation to cardiovascular health and rehabilitation. Despite this, gaps remain in terms of methodological consistency and standardized protocols. Addressing these issues could improve the applicability and scientific impact of this training modality.
    Keywords:  aging; bibliometric analysis; cardiovascular health; isometric training; rehabilitation
    DOI:  https://doi.org/10.3390/sports13050145
  11. Int J Oral Maxillofac Implants. 2025 May 27. 0(0): 1-29
    Osseodensification in Oral Implantology: A Bibliometric Analysis.
    Adil Basman, Yusuf Tatoglu.
       PURPOSE: This study aims to perform a comprehensive bibliometric analysis of the available literature on osseodensification as a surgical method for implant site preparation, to identify research trends and areas that require further investigation.
    MATERIALS AND METHODS: A refined search was conducted in the Web of Science Core Collection using keywords related to osseodensification. No language restrictions were applied. Publications published. between February 2016 and November 2023 were analyzed for bibliographic characteristics, including study design, level of evidence (LoE), countries, authorship, journal impact factor, and author keywords using VOSviewer software as well as funding analysis were conducted.
    RESULTS: A total of 63 publications were included to the study. The analyzed publications gathered 673 citations, with a mean of 10.68±17.37 citations. No significant difference in citation count was observed between original articles and reviews (p=0.884). 265 authors from 29 countries contributed to the publications with an international collaboration of 82%. The USA was the most prominent country with 23 publications. 52% of the publications were preclinical with LoE 0, followed by 13% with LoE IV and 11% with LoE II. Primary research topics included implant stability, osseointegration, and bone density.
    CONCLUSION: Osseodensification shows promise as an alternative technique for implant site preparation, enhancing primary stability in low-density bone regions. While preclinical studies indicate favorable outcomes, further clinical research is necessary to validate these findings.
    Keywords:  Osseodensification; bibliometric analysis; dental implants; osseointegration; primary stability
    DOI:  https://doi.org/10.11607/jomi.11230
  12. Healthcare (Basel). 2025 May 14. pii: 1146. [Epub ahead of print]13(10):
    Bibliometric Analysis of Research Trends and Global Collaborations in Anesthesia on Neuromuscular Blockers and Antagonists (2000-2024).
    Turan Evran, Hüseyin Özçınar, İsmet Çopur, Beliz Bilgili.
      (1) Background: The aim of this bibliometric study is to analyze global research trends, citation impact, and scientific collaborations in the field of neuromuscular blockers (NMBAs) and their antagonists between 2000 and 2024. (2) Methods: Data were retrieved from the Web of Science Core Collection (WoSCC) using Boolean search strategies. Bibliometric analyses were conducted using R bibliometrix, VOSviewer, and CiteSpace software to visualize collaboration networks, keyword trends, and citation bursts. (3) Results: A total of 499 articles were analyzed, with the United States of America (USA), China, and South Korea leading in productivity, while France had the highest citation impact. Influential authors included Mertes PM and Fuchs-Buder T. Emerging topics such as sugammadex, sevoflurane, and neuromuscular monitoring were identified, reflecting a shift from pharmacokinetic studies to safety and monitoring strategies. (4) Conclusions: The findings indicate a marked increase in studies on neuromuscular monitoring and reversal agents, such as sugammadex, over the past two decades. The USA, France, and China emerged as the most contributory countries in NMBAs research, with their extensive international collaborations playing a pivotal role in shaping scientific progress. Highly influential studies have predominantly focused on NMBA pharmacokinetics, safety, anaphylaxis risks, and the clinical benefits of sugammadex, underscoring its critical role in reducing residual neuromuscular blockade (rNMB) and enhancing patient safety.
    Keywords:  anesthesia; bibliometrics; cholinesterase inhibitors; neuromuscular blocking agents; neuromuscular depolarizing agents; neuromuscular nondepolarizing agents; research; trends
    DOI:  https://doi.org/10.3390/healthcare13101146
  13. Nat Sci Sleep. 2025 ;17 1021-1035
    Trends and Emerging Research Areas in Postoperative Sleep Disturbances: A Bibliometric Analysis.
    Wei Du, Xi Qiao, Wei Liu, Chao Li, Huiqun Jia.
       Purpose: Postoperative sleep disturbance (PSD) is highly prevalent and significantly affects patient prognosis. Studies on PSD have received increasing attention, resulting in a surge in related publications. However, comprehensive analyses that can objectively reflect changes in scientific knowledge and identify the latest research trends in this field are lacking.
    Methods: Articles and reviews focusing on PSD were extracted from the Web of Science Core Collection database. Bibliometrix, VOSviewer, and CiteSpace were used to conduct bibliometric analysis and map the visualization network.
    Results: A total of 1,559 publications were extracted from the database, including 1,370 articles and 189 reviews. There has been a consistent increase in the number of publications, with an average annual growth rate of 16.56%, led by the United States in terms of research output. Notably, the University of Toronto was a prominent contributor. Co-cited reference network analysis revealed 17 well-structured networks (Q = 0.8174, S = 0.9441). Six major research trends were identified: mechanisms of sleep related to anesthesia, role of melatonin in sleep disturbances, pain management strategies, effects of analgesic drugs, impact of dexmedetomidine on sleep quality, and postoperative recovery. Keywords analysis highlighted the emerging roles of dexmedetomidine, neuroinflammation, and acupuncture.
    Conclusion: Bibliometric analysis provides a helpful summary of postoperative sleep disturbances that have changed over time, by identifying knowledge points and developing trends. Future research should focus on integrating multidisciplinary approaches, exploring neuroinflammation, evaluating non-pharmacological interventions and long-term outcomes, which will advance scientific knowledge, enhance clinical practice, and improve patient outcomes and quality of life.
    Keywords:  CiteSpace; PSD; VOSviewer; bibliometrics; postoperative sleep disturbances; sleep disorders; visual analysis
    DOI:  https://doi.org/10.2147/NSS.S515862
  14. Front Neurosci. 2025 ;19 1595061
    Transcranial ultrasound stimulation in neuromodulation: a bibliometric analysis from 2004 to 2024.
    Jingxuan Wang, Yuling Wang, Shuyan Qie.
       Background: Transcranial ultrasound stimulation (TUS) is a non-invasive neuromodulation technique with promising clinical potential. Its therapeutic efficacy and safety are significantly influenced by stimulation parameters. However, the global research hotspots and future research trends of TUS application in the field of rehabilitation are unclear. This study analyzes the status of TUS research. Understand the annual publication trends, international and institutional cooperation pattern and influential authors and journals and keyword hotspot.
    Methods: A comprehensive literature search was conducted on the Web of Science core database using TUS-related subject headings until 27 December 2024. Two researchers independently screened articles based on pre-determined inclusion and exclusion criteria. Software packages such as CiteSpace and VOSviewer were used to visualize the results.
    Results: A total of 577 literatures were included. The results show that the annual publication volume shows an increasing trend, reaching a peak in 2024. The United States, China and Germany dominated the number of publications, with the largest number of institutions being Harvard University, the University of Toronto and Brigham and Women's Hospital. Brain stimulation is the journal with the most articles and citations. Research hotspots include transcranial magnetic stimulation, noninvasive brain stimulation, Parkinson's disease, and Alzheimer's disease.
    Conclusion: A bibliometric analysis of the literature shows that research interest in transcranial ultrasound stimulation is growing rapidly, with annual publications growing exponentially since 2013 and receiving increasing attention from researchers. The findings suggest that TUS is currently used primarily in neurological diseases, particularly in the study of Parkinson's disease and Alzheimer's disease. At the same time, it is found that an emerging international cooperation model with the partnership between the United States, China and Germany as the core has gradually taken shape. Although preclinical studies have shown promising neuromodulator effects, the current study suggests that TUS needs to undergo further multicenter clinical validation. These findings provide evidence to guide future research priorities for non-invasive neuromodulation.
    Keywords:  bibliometric analysis; neuromodulation; non-invasive brain stimulation; physiotherapy; transcranial ultrasound stimulation
    DOI:  https://doi.org/10.3389/fnins.2025.1595061
  15. Drug Des Devel Ther. 2025 ;19 4245-4262
    Bibliometrics Analysis and Knowledge Mapping of Fragment-Based Drug Design Research: Trends from 2015 to 2024.
    Chenming He, Jirong Zhang, Runze Zhang, Liang Liu, Jielian Luo, Wen Zhang, Bangjiang Fang.
       Purpose: This study systematically analyzed available literature related to fragment-based drug design (FBDD) published between 2015 and 2024 using bibliometric methods to identify research trends, hotspots, and emerging frontiers. The findings provide valuable information and a comprehensive reference for future FBDD research and drug development.
    Methods: The relevant literature was comprehensively searched from the Web of Science Core Collection (WOSCC) database using the keywords "Fragment-based drug design" or "FBDD", covering articles published between January 1, 2015 and November 1, 2024. A total of 1,301 papers were included. Bibliometric analysis and knowledge mapping were conducted using the RStudio's bibliometrix-biblioshiny package, CiteSpace, and VOSviewer software, assessing multiple dimensions such as journal co-occurrence, keyword density, institutional collaboration, and citation patterns.
    Results: The research output in FBDD revealed fluctuating growth, with an average annual growth rate of 1.42%. The United States and China lead global research with 889 and 719 publications, respectively, contributing significantly to international collaboration (34.82%). Prominent research institutions included the Center National de la Recherche Scientifique (CNRS), the University of Cambridge, and the Chinese Academy of Sciences, demonstrating strong academic influence. Key contributors such as Abell, C. Blundell, TL, and Johnson, CN, were among the top ten high-impact authors, significantly shaping the FBDD landscape through highly cited publications. Influential journals included the Journal of Medicinal Chemistry, Journal of Chemical Information and Modeling, and the European Journal of Medicinal Chemistry, each highly recognized within the FBDD research community. Keyword analysis indicated core research directions focused on "fragment-based drug discovery", "molecular docking", and "drug discovery", reflecting key technological advancements and research hotspots.
    Conclusion: FBDD remains a dynamic field with ongoing global academic attention. Future research directions are likely to emphasize innovations in computational simulation, targeted drug screening, and molecular docking techniques, facilitating the advancement and development of novel therapeutic agents.
    Keywords:  bibliometrics; drug discovery; fragment-based drug design; knowledge mapping; research trends
    DOI:  https://doi.org/10.2147/DDDT.S518489
  16. Front Med (Lausanne). 2025 ;12 1554875
    Research hotspots and trends in unexplained recurrent spontaneous abortion (URSA) from 2014 to 2024: a bibliometric analysis.
    Yishi Jiang, Yan Zhang, Yuyan Li, Yan Che.
       Introduction: Recurrent spontaneous abortion (RSA) represents a significant challenge in obstetrics and reproductive medicine. Causative factors in 40%-50% of RSA couples remain unknown, a condition termed unexplained recurrent spontaneous abortion (URSA). This study employed bibliometric analysis to elucidate global research trends and identify key areas of interest in URSA.
    Methods: We utilized the Web of Science Core Collection (WoSCC), including Science Citation Index Expanded (SCI-EXPANDED) and Social Sciences Citation Index (SSCI), as our data source. Our search encompassed all publications on URSA published between 1 January 2014 and 30 October 2024. Following rigorous removal of duplicates, we retained 586 relevant publications, including 532 original articles and 54 reviews. We conducted bibliometric analysis using CiteSpace, VOSviewer and Microsoft Excel.
    Results: Analysis of annual publications and their citations demonstrated significant growth over the last 10 years. China, the United States and Iran emerged as the most productive countries in the field. Author distribution indicated the absence of a cohesive core author group, suggesting a dispersed research community. The top five cited publications included one prospective observational study, one randomized controlled trial, two reviews, and one immunohistochemistry study, focusing on the etiology, interventions, and therapies of URSA. Keyword cluster analysis identified six categories, with the top three keywords being "expression," "polymorphisms," and "regulatory T-cells."
    Conclusion: This bibliometric analysis reveals three key research domains over the last decade in URSA: immunological mechanism and therapies, genetic mechanism, and anticoagulation therapies. While these areas have advanced our understanding, limitations persist in etiological heterogeneity and therapeutic inconsistencies. Future studies should prioritize rigorous multicenter trials with phenotypic stratification, and multi-omics approaches for mechanistic insights. Enhanced global collaboration and interdisciplinary integration are essential to transition from empirical management to evidence-based precision medicine in URSA.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; habitual abortion; spontaneous abortion; unexplained recurrent spontaneous abortion (URSA); visual analysis; women health
    DOI:  https://doi.org/10.3389/fmed.2025.1554875
  17. Front Aging Neurosci. 2025 ;17 1586282
    Knowledge map of artificial intelligence in neurodegenerative diseases: a decade-long bibliometric and visualization study.
    Junwei Huang, Shuqi Wang, Xuankai Liao, Danting Su, Rubing Lin, Tao Zhang, Long Zhao.
       Background: As the incidence of neurodegenerative diseases increases, the related AI research is getting more and more advanced. In this study, we analyze the literature in this field over the last decade through bibliometric and visualization methods with the aim of mining the prominent journals, institutions, authors, and countries in this field and analyzing the keywords in order to speculate on possible future research trends.
    Methods: Our study extracted 1,921 relevant publications spanning 2015-2025 from the Web of Science Core Collection database. We conducted comprehensive bibliometric analyses and knowledge mapping visualizations using established scientometric tools: CiteSpace and Bibliometrix.
    Results: A total of 1921 documents were included in the study, the number of publications in this field showed an overall increasing trend, and the average number of citations showed a downward trend since 2019. Among the journals, Scientific Reports had the highest number of publications. In addition, we identified 22 core journals. Institution wise, University of London has the highest participation. Among the authors, the highest number of publications is Benzinger, Tammie. The highest number of citations is Fingere Elizabeth. At the national level, the United States is number one in the world in terms of influence in this field, and China is ranked number two, both of which are well ahead of other countries and are major contributors to this field. The analysis of keywords showed the centrality of Alzheimer disease, machine learning, Parkinsons disease, and deep learning. All the studies were clustered based on keywords to get seven clusters: 0. immune infiltration; 1. Parkinsons disease; 2. multiple sclerosis; 3. mild cognitive impairment; 4. deep learning; 5. machine learning; 6. freesurfer; 7. scale. In addition, we also found the continuation of the trending topics, which are Parkinsons disease, deep learning, and machine learning.
    Conclusion: Based on the relationship between keywords and time, we speculate that there are four possible research trends: 1. Precision diagnosis with multimodal data fusion. 2. Pathological mechanism analysis and target discovery. 3. Interpretable AI and clinical translation. 4. Technology differentiation for subdivided diseases.
    Keywords:  Parkinson’s disease; Web of Science; artificial intelligence; bibliometrics; neurodegenerative diseases
    DOI:  https://doi.org/10.3389/fnagi.2025.1586282
  18. Front Pharmacol. 2025 ;16 1584383
    Global trends and collaborations in bortezomib-induced neurotoxicity research: a bibliometric analysis (2002-2024).
    Pin Wang, Jiaqi Liu, Lingling Cheng, Weiying Gu, Yunlong Tang, Yu Shao.
       Objectives: Hematological malignancies pose significant health challenges, with bortezomib emerging as a key therapeutic agent. However, its use is complicated by neurotoxicity, a side effect that urgently requires mitigation strategies. This study aims to provide a comprehensive bibliometric analysis to map the intellectual structure, historical trends, and emerging research fronts in the field of bortezomib-induced neurotoxicity.
    Methods: We conducted a systematic search in the Web of Science Core Collection, capturing literature from 2002 to 2024. Articles written in English were selected for analysis. Bibliometric analysis was performed using VOSviewer, CiteSpace, and R 4.3.3 to visualize collaborations, keyword co-occurrences, and bibliographic coupling.
    Results: The overview of this study reveals a rich tapestry of academic engagement encompassing 745 publications. The USA and China were the most productive countries, with Harvard University and the Dana-Farber Cancer Institute leading in institutional contributions. The New England Journal of Medicine stood out as the most influential journal. Prominent authors like Richardson Paul G. showcased the highest impact, with central research themes focusing on therapeutic approaches and peripheral neuropathy.
    Conclusion: This bibliometric analysis provides a detailed overview of the research landscape in bortezomib-induced neurotoxicity, identifying the USA and China as leading contributors and highlighting the central focus on therapeutic strategies and peripheral neuropathy management. These findings emphasize the need for global collaboration to develop effective mitigation strategies for neurotoxicity and improve patient outcomes. Insights from this study can guide future research efforts and inform clinical practices in managing bortezomib-related side effects.
    Keywords:  bibliometrics; bortezomib; hematological malignancies; neurotoxicity; research trends
    DOI:  https://doi.org/10.3389/fphar.2025.1584383
  19. Front Oncol. 2025 ;15 1580848
    The evolution of FLASH radiotherapy: a bibliometric analysis.
    Shuokai Jia, Weige Wei, Yiwen He, Haichuan Yan, Shiru Zou, Yanmei Hao, Qing Xiao, Guangjun Li.
       Introduction: FLASH radiotherapy (FLASH-RT) represents a groundbreaking technique, characterized by its ultra-high dose rate and its remarkable ability to spare normal tissues from damage. Numerous studies on FLASH-RT have been conducted worldwide. However, to date, no comprehensive bibliometric analysis has been performed in this field. This study aims to provide an overview of the advancements in FLASH-RT and identify potential future research directions through bibliometric analysis.
    Method and materials: The research team performed a literature search in the Web of Science Core Collection (WOSCC), covering the period from 1967 to 2024, and identified 461 publications relevant to the field of interest. Visualization tools, including VOSviewer, CiteSpace, and Bibliometrix, were employed to analyze countries, institutions, authors, journals, references, and keywords, thereby uncovering research frontiers and hotspots within the field.
    Results: In recent years, a considerable number of publications on FLASH-RT have emerged. The United States has the highest number of publications (n=208). The institution with the highest publication count is "Lausanne University Hospital" (n=39). The author with the most citations is "Vozenin, M" (n=31), while the author with the most co-citations is "Montay-Gruel, P" (n=812). Medical Physics is the journal with the highest number of both publications and co-citations, whereas Radiotherapy and Oncology has the highest number of citations. The paper titled "Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice" has the highest number of both citations and co-citations. The most frequently co-occurring keywords is "FLASH radiotherapy" (n=379).
    Conclusions: Our bibliometric analysis of FLASH-RT explores key dimensions of the field, including publication trends, international collaborations, influential journals and authors, and keyword evolution. It assesses FLASH-RT's historical development, current global status, and recent progress in biological mechanisms, equipment, and clinical translation, aiming to offer researchers a comprehensive overview.
    Keywords:  FLASH radiotherapy (FLASH-RT); bibliometric analysis; biological mechanisms; device; preclinical and clinical trials; ultra-high dose rate (UHDR)
    DOI:  https://doi.org/10.3389/fonc.2025.1580848
  20. J Craniofac Surg. 2025 May 29.
    Mapping the Research Landscape of Cleft Lip and Palate Management: Insights From a Bibliometric Perspective.
    Yungang Hu, Huimin Wu, Yihan Huang, Qi Zeng, Xiaolin Li, Guanqun Wan.
       BACKGROUND: Cleft lip and palate (CLP) is the most common congenital anomalous deformity of the oral face, and treatment of CLP has changed dramatically with the development of surgical techniques and advances in humanistic medicine. However, a comprehensive bibliometric analysis of research trends in this field is still lacking.
    METHODS: The authors systematically analyzed 3994 publications related to CLP treatment in the Web of Science Core Collection from 2005 to 2024 by bibliometric methods.
    RESULTS: The results showed that global CLP research has shown a continuous growth trend, with the USA leading the way with 1084 publications, and the United Kingdom and The Netherlands significantly leading the way in terms of publication quality (average number of citation 26.13/24.76). Core research institutions include University of Sao Paulo and Chang Gung Hospital. Core authors Shi Bing and Semb Gunvor lead the field with 45 and 44 publications, respectively. Keyword analysis reveals that research hotspots have shifted from basic repair to multidimensional rehabilitation, including emerging directions such as symmetry aesthetics, orthodontic treatment, and speech therapy. Clustering of co-cited literature identified 19 themes, highlighting the importance of nonsurgical dimensions such as psychological adjustment and unmet needs.
    CONCLUSION: This study reveals for the first time the evolution of the knowledge structure of CLP treatment through visual analysis, providing valuable insights into clinical care and contributing to the advancement of the field of CLP management.
    Keywords:  Bibliometric analysis; cleft lip and palate; management; psychological; speech therapy
    DOI:  https://doi.org/10.1097/SCS.0000000000011518
  21. Medicine (Baltimore). 2025 May 30. 104(22): e42603
    Global status and trends of invasive pulmonary aspergillosis: A bibliometric study.
    Wei Wang, Xinyu Chi, Jianyu Ji, Junlin Zhang, Shulin Xiang, Bin Xiong, Jing Pang.
      While previous studies have investigated the pathophysiology, epidemiology, and risk factors of invasive pulmonary aspergillosis (IPA), research trends and hotspots on this topic remain relatively unexplored. This study aims to develop a visual knowledge map using bibliometric analysis to identify research hotspots and predict future trends in IPA research. A systematic search was conducted on the Web of Science Core Collection for articles published between January 1, 2000, and March 31, 2024. Tools such as CiteSpace and VOSviewer were used to analyze annual publication trends, contributions by countries, institutions, journals, authors, and references, as well as key research areas to identify current hotspots and future directions. A total of 4058 articles were included, representing contributions from 3409 institutions across 749 journals and 214 countries or regions. The United States published the most articles (1312) and emerged as the most influential country in this field. Medical Mycology published the highest number of articles (206), while Clinical Infectious Diseases was the most cited journal (27,450 citations). Keyword clustering revealed 4 major themes: diagnostics (e.g., galactomannan assays), clinical management (e.g., antifungal therapy), at-risk populations (e.g., transplant recipients), and emerging trends (e.g., COVID-19-associated IPA). Temporal analysis identified 3 distinct research phases: early phase (2000-2007): focus on bone marrow transplantation and diagnostic methods. mid-phase (2008-2018): emphasis on clinical guidelines and epidemiological studies. Recent phase (2019-2024): shift toward COVID-19-associated IPA and its impacts. By applying bibliometric methods to analyze IPA research, this study identifies key authors, countries, institutions, and journals in terms of collaboration and influence. It enhances the understanding of research hotspots in the field and provides insights into potential future collaborations and research directions.
    Keywords:  CiteSpace; VOSviewer; Web of Science Core Collection; bibliometric; invasive pulmonary aspergillosis; research hotspots
    DOI:  https://doi.org/10.1097/MD.0000000000042603
  22. Medicine (Baltimore). 2025 May 30. 104(22): e42707
    A bibliometric review and visualization of research on myocardial ischemia/reperfusion injury in patients with diabetes mellitus from 2004 to 2024.
    Yunzhao Yang, Juan Dou, Yang Wu.
       BACKGROUND: The incidence of diabetes mellitus (DM) is increasing annually, and hearts of patients with DM are more sensitive to myocardial ischemia/reperfusion (MI/R) injury. However, the specific mechanisms remain unknown. Through a bibliometric analysis of published research, this study primarily summarizes and clarifies the current status of research on diabetic MI/R injury.
    METHODS: Publications related to MI/R injury in DM from January 1, 2004, to July 31, 2024, were obtained by searching the Web of Science Core Collection. The bibliometric method was adopted using Excel 2021, CiteSpace, VOSviewer, Pajek and the R package "Bibliometrix."
    RESULTS: In total, 634 research papers and 221 reviews were published during this period that fit the criteria. The number of annual scientific publications and citations on diabetic MI/R injury has steadily increased. The majority of these studies were published by 1164 institutions from 70 countries, with China and the United States ranking first and second, respectively, in terms of publication volume. Among the leading institutions in this field, the Air Force Military Medical University, Wuhan University, and the University of Hong Kong were found to occupy the top positions. Keyword analysis reveals that recent research hotspots include antidiabetic agents, anesthetics and extracellular vesicles. Emerging trends such as ferroptosis, mitophagy, and gut microbiota are closely related to future research directions.
    CONCLUSION: This study provided a detailed overview of the key contributors, institutions, and countries, highlighting the changes and progression of hotspots in diabetic MI/R injury. China leads the world in paper production; however, international cooperation is essential for enhancing the quality of research. In our study, we found that bibliometric analysis and literature visualization will help investigators gain a deeper understanding of the progress in the research into diabetic MI/R injury.
    Keywords:  CiteSpace; VOSviewer; Web of Science; bibliometric analysis; diabetic myocardial ischemia/reperfusion injury; visual analysis
    DOI:  https://doi.org/10.1097/MD.0000000000042707
  23. Medicine (Baltimore). 2025 May 30. 104(22): e42628
    A bibliometric analysis of chronic kidney disease-associated pruritus from 2004 to 2023.
    Pan Chen, Rui-Zhi Tan, Wen-Jing Zhao, Jing Gao, Li Wang, Hong-Wei Su, Jian Liu.
       BACKGROUND: Chronic kidney disease-associated pruritus (CKD-aP) is an itch directly associated with kidney disease. Currently, there is no bibliometric analysis literature in this field. Therefore, this study employs bibliometric methods to understand the characteristics, hotspots, and frontiers of global CKD-aP research in the past 20 years.
    METHODS: Publications relevant to CKD-aP, published from 2004 to 2023, were retrieved from the Science Citation Index-Expanded Web of Science Core Collection. Then, we used VOSviewer, CiteSpace, and Scimago Graphica software to construct visualization maps.
    RESULTS: A total of 472 papers were retrieved. The author with the most published papers is Szepietowski (19 papers). Regarding institutions, the Medical University of Wroclaw (18 papers) has the highest publication output. The most prolific country is the United States (112 papers). The author with the highest number of citations is Pisoni RL (199 citations). Nephrology Dialysis Transplantation (401 citations) is the journal with the highest citation frequency. Cluster analysis of co-citation shows the largest cluster and current hotspot as "CKD-associated pruritus" (140 papers). The most frequently occurring keyword is "dialysis" (181 occurrences), and the keyword with the highest burst intensity is "skin" (5.75). Keywords related to the etiology and treatment of CKD-aP include "histamine," "naltrexone," and "gabapentin."
    CONCLUSIONS: Exploring the definite etiology and mechanisms of CKD-aP and effective treatment methods are crucial research topics in the past and future. Additionally, this study provides a fresh perspective on the CKD-aP field, offering valuable insights for future research endeavors.
    Keywords:  Citespace; VOSviewer; bibliometrics; chronic kidney disease-associated pruritus; uremic pruritus
    DOI:  https://doi.org/10.1097/MD.0000000000042628
  24. Chronobiol Int. 2025 May 30. 1-14
    Global research trends on exercise and circadian rhythm: A bibliometric analysis.
    Yu Gu, Yongchao Xie, Wenduo Liu, Zilin Wang, Dong-Hun Seong, Sang Hyun Kim.
      Recent advancements in the field of exercise and circadian rhythms have brought attention to the potential for tailored exercise strategies based on individual biological rhythms, aiming to optimize both health and performance, yet there is a lack of bibliometric analysis within this specific area of research. This study seeks to provide an extensive insight into the knowledge structure and primary research focuses on the correlation between exercise and circadian rhythms using bibliometric analysis. Publications pertinent to exercise and circadian rhythms were sourced from the Web of Science Core Collection (WoSCC) database. Utilizing VOSviewer, CiteSpace, and the R package "bibliometrix," a thorough bibliometric analysis was conducted. The analysis encompassed publications from 83 countries and 2025 institutions focusing on exercise and circadian rhythms. Leading contributors included the USA, England, France, Japan, and Germany, with an increasing number of publications annually. Notable institutions like Liverpool John Moores University, Univ Sfax, Brigham Women's Hosp, and Univ Milan ranked among the top contributors. Chronobiology International emerged as the most popular journal in this domain. These publications were attributed to 4402 authors, with Thomas Reilly and Greg Atkinson receiving the most citations, particularly Reilly being the most co-cited author. Dominant research topics included circadian rhythm, quality, skeletal muscle, and entrainment, while emerging hotspots comprised sports performance, mental health validity, older adults, and the sleep-wake cycle. This study marks the first comprehensive bibliometric analysis summarizing research trends and developments in exercise and circadian rhythms. This collection pinpoints the latest research frontiers and promising avenues, acting as a valuable resource for researchers investigating the connection between exercise and circadian rhythms.
    Keywords:  Exercise; circadian rhythm; health; metabolism; non-photic zeitgeber
    DOI:  https://doi.org/10.1080/07420528.2025.2501339
  25. Discov Oncol. 2025 May 30. 16(1): 960
    Exploring the use of traditional Chinese medicine exercises for cancer patients from the perspective of bibliometrics.
    Ying Qu, Yuting Yang, Yan Huang, Yukun He, Jingqi Gao, Chunju Deng, Lei Gu.
       BACKGROUND: Cancer is a global health issue, and as the side effects of conventional treatments become more noticeable, many patients turn to complementary therapies, especially traditional Chinese medicine exercises. These exercises help regulate the mind and body, enhance immune function, and alleviate side effects. Despite the potential of these treatments, bibliometric studies on this topic are limited.
    METHODS: For this study, we analyzed literature from the Web of Science Core Collection (WoSCC) from 2011 to 2024 and used VOSviewer (version 1.6.20) and CiteSpace (version 6.4.R1) to explore research trends, academic impact, collaboration networks, and keyword hotspots.
    RESULTS: A total of 261 articles from 2011 to 2024 were included, with the number of annual publications increasing from 2 to 37. China led with 144 articles and 2678 citations, followed by the U.S. with 83 articles and 3732 citations. The University of Hong Kong and Harvard Medical School were the top institutions. The key authors included Cheung Denise Shuk Ting and Takemura Naomi, each of whom published 8 papers. Integrative Cancer Therapies had the greatest impact. Keyword analysis revealed research hotspots such as "cancer rehabilitation", "immune regulation", "mind-body exercise", and "psychological stress relief".
    CONCLUSION: The application of Chinese medicine exercises in adjunctive cancer therapy is gradually becoming a popular research topic. Bibliometric analysis has revealed the development trends and frontier issues in this field, providing scientific evidence for future research directions. There is still great potential for further research, particularly in areas such as cancer immune regulation and psychological rehabilitation.
    Keywords:  Bibliometrics; Cancer; Traditional Chinese medicine exercises; Visualization; Web of Science
    DOI:  https://doi.org/10.1007/s12672-025-02747-1
  26. Oral Radiol. 2025 May 30.
    The use of ultrasonography in dentistry: a bibliometric analysis.
    Sedef Kotanli, Mehmet Emin Aydemir, Mehmet Emin Dogan, Mehmet Veysel Kotanli.
       OBJECTIVES: In this bibliometric analysis, various parameters such as leading journals, universities, countries, authors and keywords related to the use of ultrasonography (USG) in dentistry were analysed with the help of bibliometric mapping, aiming to help researchers evaluate scientific results on this subject and design future research.
    METHODS: In this bibliometric analysis, using the Web of Science (WoS) database various factors such as publication date, number of citations, publication language, journals published, countries, and keywords of articles covering research on the use of USG in dentistry between 1981 and 2024 were examined.
    RESULTS: It has been determined that the number of articles and citations regarding the use of USG in dentistry is increasing day by day. While 6 articles were published in this field in 2000, 94 publications were made in 2023. While 25 citations were made in 2000 for articles published on the use of USG in dentistry, this number reached 2334 in 2023. The country with the most publications in this field was the USA, and the journal with the most publications was Dentomaxillofacial Radiology.
    CONCLUSION: The findings of this current analysis may help researchers categorize scientific conclusions regarding the use of USG in dentistry and thus select issues to examine when designing future research.
    Keywords:  Bibliometric; Sonography; Ultrasonography; Ultrasound; VOSviewer software
    DOI:  https://doi.org/10.1007/s11282-025-00830-5
  27. J Neurosurg Spine. 2025 May 30. 1-6
    Female authorship trends in high-impact spine surgery journals.
    Courtney Deaver, Isabel L Bauer, Annemarie Pico, Kristin Nosova, Mahesh Challapalli, Naushaba Khan, Maria Jose Cavagnaro, Giovanni Barbagli, Nikhil Dholaria, James Kelbert, Diego T Soto Rubio, Amna Hussein, Julie Mayeku, Ibrahim A Alhalal, Niels Pacheco, Abdullah Al-Arfaj, Chao Li, Michael Prim, Ali A Baaj.
       OBJECTIVE: The objective of this study was to examine the trends in female authorship in high-impact spine journals and identify barriers present for female authors in spine surgery.
    METHODS: A bibliometric analysis of seven spine surgery journals was conducted, covering publications from 2016 to 2021. First and senior author genders were determined using Genderize.io, supplemented by manual verification for ambiguous cases. Geographic and specialty-specific trends were analyzed, focusing on neurosurgery and orthopedic surgery.
    RESULTS: Among 11,757 identified first authors and 11,231 identified senior authors, 13.4% of first authors and 9.3% of senior authors were female. Gender concordance analysis showed that with a female senior author, 26.7% of first authors were female compared with 12.5% with male senior authors (p < 0.00001). In 2021, there was no significant difference in the proportion of female senior authors between orthopedic (2.7%) and neurosurgery (1.2%) specialties. Papers with female authors were published in higher-impact factor journals, with the average impact factor for female first authors being 3.08 compared with the male average of 3.02, and for female senior authors, the average impact factor was 3.10 compared with their male counterparts' average of 3.02 (female first authors: p < 0.05, female senior authors: p < 0.001). US publications had fewer female first authors compared with international publications (p < 0.001).
    CONCLUSIONS: This study underscores the need for targeted strategies to overcome barriers to female participation and advancement in spine surgery. Enhancing mentorship and addressing implicit biases are essential to attract and retain more women in this field, ultimately benefiting the specialty and patient care.
    Keywords:  authorship trends; bibliometric analysis; female authorship; spine journal authorship
    DOI:  https://doi.org/10.3171/2025.2.SPINE24723
  28. Photodiagnosis Photodyn Ther. 2025 May 28. pii: S1572-1000(25)00186-3. [Epub ahead of print] 104654
    Photodynamic Therapy in Ocular Oncology: A Bibliometric Analysis (1987-2024).
    Ceren Türkoğlu, Aslan Aykut.
       BACKGROUND: Photodynamic therapy (PDT) is a minimally invasive modality widely employed in ocular oncology, utilizing photosensitizers such as verteporfin to induce localized cytotoxic effects. While PDT is commonly applied in the management of benign intraocular tumors and selectively for malignant lesions, bibliometric analyses in this field remain scarce. This study aims to address this gap by analyzing bibliometric trends and mapping the evolution of PDT research in ocular oncology.
    METHODS: A bibliometric analysis was conducted using the Web of Science Core Collection, targeting PDT in ocular tumors. Data were screened for relevance, refined using OpenRefine, and analyzed in Microsoft Excel for publication trends. VOSviewer was used to visualize collaboration networks and keyword co-occurrence. Key indicators such as publication output, citations, authorship, institutional contributions, and journal distribution were assessed.
    RESULTS: A total of 177 publications (1987-2024) were identified, with original articles comprising 67.7%. The United States led in publication count (n=63), total citations (1,074), and H-index (20). Investigative Ophthalmology & Visual Science and Retina were the most prolific journals. A decline in publication volume was noted post-2020, coinciding with a global verteporfin shortage. Keyword analysis showed a primary focus on circumscribed choroidal hemangioma, with recent interest shifting toward metastasis and alternative therapies. The most prolific authors were Shields CL and Shields JA, while Schmidt-Erfurth U had the highest citation count.
    CONCLUSION: This study presents the first comprehensive bibliometric mapping of PDT in ocular oncology, highlighting research trends, influential contributors, and the impact of external factors on scholarly output.
    Keywords:  Bibliometric Analysis; Ocular Oncology; Photodynamic Therapy; Research Trends; Verteporfin
    DOI:  https://doi.org/10.1016/j.pdpdt.2025.104654
  29. Front Immunol. 2025 ;16 1580222
    A comprehensive bibliometric analysis of ferroptosis in tumor resistance: development and emerging trends.
    Liangyun Xie, Yafei Zhang, Xiedong Niu, Yuan Kang, Wenyao Li, Jun Yao.
       Background: Ferroptosis is a regulated form of cell death characterized by iron dependency, lipid peroxidation, and oxidative stress. Since its discovery in 2012, ferroptosis has attracted significant interest for its potential to counteract tumor resistance across various therapeutic modalities, including chemotherapy, radiotherapy, immunotherapy, and targeted therapy. Despite notable progress, a systematic understanding of its underlying molecular mechanisms and translational potential remains underdeveloped, thus necessitating a comprehensive bibliometric analysis.
    Methods: We employed bibliometric tools, including VOSviewer, CiteSpace, and bibliometric.com, to analyze 2,663 articles related to ferroptosis and tumor resistance indexed in the Web of Science Core Collection from 2014 to 2024. The analysis included co-occurrence, co-citation, and clustering techniques to explore trends, influential keywords, prominent journals, leading institutions, and key contributors. Citation burst detection and temporal analysis were used to uncover emerging research hotspots and track the field's evolution.
    Results: Over the past decade, the volume of publications in this field has grown rapidly, with China and the United States leading in both research output and academic influence. Notable institutions such as Central South University and Fudan University contributed significantly, while Kang Rui and Tang Daolin emerged as prolific authors. Key research hotspots identified include oxidative stress, tumor microenvironment, and nanomedicine, with emerging themes such as immunotherapy and autophagy gaining prominence. Temporal trends indicated a shift from mechanistic studies toward translational applications, emphasizing the integration of ferroptosis in clinical strategies to address tumor resistance.
    Conclusions: This bibliometric analysis highlights ferroptosis as a rapidly evolving field with significant contributions to understanding tumor resistance mechanisms. The identification of emerging themes and promising research directions offers valuable insights for future investigations and clinical applications of ferroptosis in overcoming tumor resistance.
    Keywords:  bibliometric analysis; ferroptosis; oxidative stress; tumor microenvironment; tumor resistance
    DOI:  https://doi.org/10.3389/fimmu.2025.1580222
  30. Front Pharmacol. 2025 ;16 1548023
    Global research on the utilization of population pharmacokinetic model: a bibliometric analysis from 2000 to 2024.
    Yucheng Yao, Liyuan Zhang, Dan Chen, Shiran Qin, Mingyu Meng, Qiuyan Guo.
       Objective: Population pharmacokinetic (PPK) model is capable of identifying the factors that influence the variability of pharmacokinetic (PK) profiles and the degree of their influence, effectively reduces unexplained variability, and demonstrates excellent predictive ability. PPK model has been successfully constructed in several populations for a variety of drugs. However, no study has yet conducted a bibliometric analysis of publications related to the PPK model. This study aims to provide a comprehensive overview of the research progress and hotspots in the field of PPK model research through bibliometric methods.
    Methods: A systematic search of the Web of Science database was conducted to collect articles and reviews related to the PPK model between 2000 and 2024. We then analyzed the data using Bibliometrix R package, Microsoft Office Excel, CiteSpace and VOSviewers.
    Results: Between 2000 and 2024, we identified a total of 6,125 papers and 128,856 citations. The average annual growth rate of the relevant publications was 10.35%, showing continued growth momentum. These research outputs are concentrated in North America, Western Europe, and East Asia, with USA leading the way with 2,340 publications and having the highest H-index (93) and total citations (54,965). Uppsala University and British Journal of Clinical Pharmacology are the institutions with the highest publication output and the most influential journals, respectively. Most of the funding agencies are from the USA and the subject categories for most publications are Pharmacology Pharmacy. In terms of author contributions, professor Karlsson MO is the leader in the field with 149 publications. In addition, wo found that "critically ill patients," "tacrolimus," "machine learning," "external evaluation," "polymyxin b," "voriconazole," "extracorporeal membrane oxygenation," "dose optimization" and "model-informed precision dosing" are current research hotspots and future research trends.
    Conclusion: This study is the first comprehensive overview of the development of PPK model and research hotspots using bibliometric methods. Our findings provide researchers, especially beginners, with insights into the application area of PPK model, helping them to grasp key information in the field.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; population pharmacokinetic model; visualization analysis
    DOI:  https://doi.org/10.3389/fphar.2025.1548023
  31. Echocardiography. 2025 Jun;42(6): e70204
    Critical Care Echocardiography: A Bibliometric Analysis of Knowledge Structure and Evolution of Development Trends From 2005 to 2024.
    Weiwei Wang, Ben Liu, Lin Wang.
       OBJECTIVE: This study aims to conduct a bibliometric analysis in the field of critical care echocardiography (CCE) and further discusses the knowledge structure and research hotspots, so as to construct a systematic framework that can provide reference for future research work in this field.
    METHODS: We collected the data from the Web of Science database, with February 21, 2025 being the cut-off date. Subsequently, a bibliometric analysis and visual mapping analysis were carried out on the collected articles by using CiteSpace and VOSviewer.
    RESULTS: The United States leads CCE research in publications. Among institutions, the Paris Public Hospital Assistance (APHP) tops in output. From the author's dimension, Mcnamara PJ was identified as the most productive author. In terms of academic journals, the Journal of Cardiothoracic and Vascular Anesthesia leads in the number of published research results on CCE. The three most frequently occurring keywords were "echocardiogram," "ICU," and "NICU." The keywords that have emerged more frequently recently were "COVID-19," "cardiogenic shock," and "point-of-care ultrasound (POCUS)." Keyword cluster analysis indicated that this field can be divided into six sub-fields, namely "congenital heart disease," "cardiac arrest," "sepsis," "heart failure," "patent ductus arteriosus," and "intensive care unit." Furthermore, we performed subgroup analyses specifically focusing on the application of CCE in COVID-19 patients and pediatric CCE, respectively.
    CONCLUSION: We conducted statistical and visual analyses of the literature related to CCE, presenting the field's knowledge structure and hotspots, offering references for relevant scholars.
    Keywords:  AI; bibliometric; critical care echocardiography; echocardiography; intensive care unit; multi‐modality
    DOI:  https://doi.org/10.1111/echo.70204
  32. J Contemp Dent Pract. 2025 Feb 01. 26(2): 217-222
    Osseointegration of Dental Implants in Irradiated Patients: A Bibliometric Study.
    Jean Montoya-Mercado, Rosabelle García-Herencia, Pedro L Tinedo-López, Fran Espinoza-Carhuancho, Josmel Pacheco-Mendoza, Frank Mayta-Tovalino.
       BACKGROUND: To analyze the osseointegration of dental implants in irradiated patients through a bibliometric study.
    MATERIALS AND METHODS: A descriptive and retrospective bibliometric study was conducted, focusing on English-language scientific publications indexed in Scopus from January 2018 to May 2024. To maintain quality and relevance, the study excluded abstracts, letters to the editor, book reviews, opinions, and symposium reports. The search, conducted on May 11, 2024, utilized the MeSH terms from the National Library of Medicine along with Boolean operators to refine the search. Relevant indicators such as citation count, publications by country, year, author, journal quartile, and more were examined. The data were analyzed using SciVal, Mendeley, Bibliometrix, and VOSviewer software.
    RESULTS: The research identified 25 relevant papers, with an annual growth rate of 16.73%. The average number of citations per paper was 9.8, with a total of 846 references and 144 authors. German institutions led in scientific production, with the highest impact seen at Hospital Santa Catarina of Brazil. Brazilian authors showed the highest citation impact, while Heiland Max attained the highest h-index. Most publications were within the first (Q1, n = 14) and second (Q2, n = 6) quartiles, with 2021 standing out as the year with the highest impact. Collaboration maps highlighted international cooperation between several countries such as the USA, Spain, China, and Chile.
    CONCLUSION: The study provides a comprehensive bibliometric analysis of osseointegration of dental implants in irradiated patients, highlighting key trends and collaborations in the field.
    CLINICAL SIGNIFICANCE: This study underscores the clinical importance of osseointegration of dental implants in patients who have undergone radiation therapy. By providing insights into trends and collaborative networks, enhances our understanding of these patterns, which can improve treatment strategies, and patient outcomes, and guide future research. Ultimately, this advances the field of dental implantology for irradiated patients. How to cite this article: Montoya-Mercado J, García-Herencia R, Tinedo-López PL, et al. Osseointegration of Dental Implants in Irradiated Patients: A Bibliometric Study. J Contemp Dent Pract 2025;26(2):217-222.
    Keywords:  Dental implant; Osseointegration; Radiated patients Radiation therapy.
    DOI:  https://doi.org/10.5005/jp-journals-10024-3823
  33. Front Immunol. 2025 ;16 1574736
    Tracing the history of clinical practice of liquid biopsy: a bibliometric analysis.
    Shuo Zhang, Hongwei Zhao, Kangchun Wang, Lijie Li, Qi Pan, Meitong Lu, Xing Zhang.
       Introduction: Liquid biopsy holds great promise in clinical diagnosis, treatment, and prognostic monitoring. This study reveals the development of liquid biopsy in clinical practice through a comprehensive bibliometric analysis.
    Methods: A total of 40 years of research literature in this field was included from the Web of Science Core Collection (WoSCC), analyzing the evolving research trends of liquid biopsy in clinical practice. We constructed co-occurrence networks for countries, institutions, authors, and keywords, integrating citation analysis and journal impact metrics to provide a comprehensive view of the research landscape in the field of liquid biopsy.
    Results: The results show a significant growth trend in the clinical practice of liquid biopsy, with China and the United States being the leading contributors. Institutions such as Harvard University and the University of California system play a central role in the global collaboration network. Cancers has become the primary publication outlet for the field, while highly cited journals like Clinical Cancer Research play a crucial role in advancing its development. Keyword analysis reveals that research has progressively expanded into clinical applications, personalized treatment, and prognostic evaluation.
    Discussion: Overall, as technology and applications continue to mature, liquid biopsy is expected to play an even greater role in the early diagnosis, treatment evaluation, and personalized treatment of cancer and other diseases.
    Keywords:  bibliometric analysis; biomarkers; cancer; clinical practice; liquid biopsy
    DOI:  https://doi.org/10.3389/fimmu.2025.1574736
  34. Front Oncol. 2025 ;15 1492880
    Research trends and hotspots of circulating tumor DNA in colorectal cancer: a bibliometric study.
    Lele Zhang, Yuzhe Zhang, Lei Chen, Xu Wang, Yulian Liu, Yishan Huang, Yu Song, Ye Zhang, Jiandong Tai.
       Introduction: Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related deaths. The current standard of care for patients with early-stage CRC includes surgical resection and, in selected patients, adjuvant chemotherapy. Circulating tumor DNA (ctDNA) testing is an important component of liquid biopsy, and with the development of testing technology, its value for clinical application has attracted widespread attention. The aim of this study was to help researchers review what has been achieved and better understand the direction of future research through bibliometric analysis.
    Methods: We used the Web of Science Core Collection database to search for ctDNA in CRC-related articles published between 2014 - 2023. Bibliometric analyses of major keywords, authors, countries, institutions, literature and journals in the field were performed using CiteSpace and VOSviewer.
    Results: The number of publications in the field has continued to increase over the last decade. The United States has the highest number of publications, and Italian research scholars have made outstanding contributions. Cancers is the journal with the highest number of publications.
    Conclusion: This study systematically summarizes the research findings in the field of ctDNA in CRC from 2014 to 2023 and describes the research hotspots and trends worldwide that can guide future research.
    Keywords:  MRD; bibliometric; circulating tumor DNA; colorectal cancer; treatment
    DOI:  https://doi.org/10.3389/fonc.2025.1492880
  35. Photobiomodul Photomed Laser Surg. 2025 May 26.
    Intense Pulsed Light for the Treatment of Dry Eye Disease: A Bibliometric and Visualized Analysis.
    Junran Li, Bo Yu, Muyao Xin, Yu Sun, Emmanuel Eric Pazo, Xiaoli Xing.
      Objective: Bibliometric study of intense pulsed light (IPL) for dry eye disease (DED) and meibomian gland dysfunction (MGD) to characterize current worldwide patterns and offer visual representations of previous and emerging trends. Background: DED is a prevalent eye condition and IPL has been reported to be an effective therapy for dry eyes. Method: This cross-sectional study examined IPL for DED research evolution and theme trends from 2015 to 2024, using bibliometric analysis of WoSCC data. We examined 4334 IPL articles for publication year, journals, authors, institutions, countries/regions, references, and keywords. Results: We found 111 articles from 2015 to 2024 articles and the annual publication rate was less than 10 from 2015 to 2017, but has steadily increased after 2018. Global publication volumes have increased by 1300% in the past decade, from 2 in 2015 to 28 in 2022. Currently, the number of articles stands at 10 in 2024. IPL for DED was published in 43 journals. Currently, the top journals publishing on this topic according to volume include Photobiomodulation, Photomedicine, and Laser Surgery, Journal of Clinical Medicine, and Cornea. Conclusions: The number of publications and citations on research related to IPL for DED treatment has steadily increased across numerous countries, institutions, and authors over the past decade. The current study illuminates the current trends, global collaboration patterns, fundamental knowledge, research hotspots, and emerging frontiers of IPL treatment. The primary focus now has been the development of innovative solutions for the treatment of DED and MGD by combining IPL with presenting DED treatment regime.
    Keywords:  Intense pulsed light; Meibomian gland dysfunction; bibliometric analysis; dry eye; global publications
    DOI:  https://doi.org/10.1089/photob.2024.0144
  36. Front Pharmacol. 2025 ;16 1603573
    Bibliometric analysis of research trends on the combination of radiotherapy and PARP inhibitors in solid tumors.
    Yuxin Chen, Zhengkun Zhang, Rutie Yin, Qingli Li, Wenhao Zhang.
       Introduction: Radiotherapy has served as a cornerstone in cancer treatment for over a century. However, the efficacy of radiotherapy is often compromised by the intrinsic and acquired radioresistance of tumors, which can lead to treatment failure and disease recurrence. Recent advancements in preclinical and clinical research have highlighted the potential synergistic efficacy of combining radiotherapy with poly-ADP-ribose polymerase inhibitors (PARPi), offering promising therapeutic avenues for solid tumors. This study employs bibliometric analysis to systematically evaluate the evolution, trends, and intellectual landscape of research on the combination of radiotherapy and PARPi in solid tumors.
    Methods: Publications addressing the combination of radiotherapy and PARPi for solid tumors between 2005 and 2024 were retrieved from the Web of Science Core Collection (WOSCC) database. Bibliometric assessments were conducted using VOSviewer and CiteSpace to analyze publication trends, collaborative networks, and research foci.
    Results: A total of 901 articles were included. The United States dominated research output, with the University of Texas MD Anderson Cancer Center identified as the most productive institution. Hannah Farmer emerged as the most frequently cited author. Keywords co-occurrence analysis revealed a thematic shift from foundational studies on molecular mechanisms, such as DNA damage response and mechanism of action of PARPi, toward clinical investigations evaluating combination therapy efficacy and safety in trials.
    Conclusion: This bibliometric analysis underscores the rapid growth of research on radiotherapy and PARPi combination therapy, with the United States maintaining a leading role due to its extensive scientific infrastructure and collaborative networks. The field has transitioned from mechanistic explorations to translational and clinical applications, reflecting progress toward therapeutic optimization. These findings provide a comprehensive overview of the knowledge structure within this domain and serve as a strategic reference for guiding future research priorities and clinical implementations.
    Keywords:  PARP inhibitors; bibliometric analysis; radiosensitization; radiotherapy; solid tumors
    DOI:  https://doi.org/10.3389/fphar.2025.1603573
  37. Front Med (Lausanne). 2025 ;12 1493459
    The role of autophagy in periodontal diseases: a bibliometric analysis from 2006 to 2023.
    Bitong Zhang, Yahui Wang, Haoxiang Chang, Chong Wang, Hong Fan, Xiuyun Ren.
       Background: Periodontal disease is a chronic inflammatory condition affecting the supporting structures of the teeth, involving complex interactions between systemic and local immune responses. Autophagy is a tightly regulated cellular process that is responsible for degrading and recycling cellular components, playing a pivotal role in maintaining cellular homeostasis and modulating inflammation in periodontal disease. In recent years, the relationship between these two factors has attracted attention from scholars globally. However, bibliometric analyses in this field are still limited.
    Objectives: To analyze the bibliometric trends and research hotspots related to the role of autophagy in periodontal disease.
    Methods: Articles and reviews examining the association between periodontal disease and autophagy were retrieved from the Web of Science Core Collection (WOSCC) on 20 June 2024. Bibliometric and knowledge mapping analyses were performed using CiteSpace [6.3. R1 (64-bit) Advanced].
    Results: Through a bibliometric analysis of literature published between 2006 and 2023 on the role of autophagy in periodontal disease, 341 relevant studies were identified. The results indicate a steady annual increase in studies on this topic, with a significant upward trend observed post-2015. Keyword analysis identifies "apoptosis," "Porphyromonas gingivalis," "oxidative stress," "inflammation," "periodontitis," "osteogenic differentiation," "cell death," and "orthodontic tooth movement" as key research hotspots. Collaboration network analysis identifies China as the leading contributor to research in this field. Document co-citation analysis highlights several influential studies examining the "double-edged sword" role of autophagy in periodontal disease, illustrating how autophagy alleviates oxidative stress and inflammation in periodontitis by removing damaged organelles, inhibiting pro-inflammatory mediators, and promoting periodontal tissue repair through the secretion of pro-angiogenic cytokines. However, excessive autophagy may lead to apoptosis when cellular stress surpasses the repair capacity. This study identifies key trends and research hotspots in autophagy and periodontal disease, underscoring the importance of international collaboration and high-impact journals for advancing the field and guiding future research.
    Conclusion: Recent studies indicate that autophagy has emerged as a critical mediator with dual roles in periodontal disease. Therefore, early control of periodontal inflammation, along with the exploration of how to harness the protective functions of autophagy, may provide future research directions for managing periodontal disease.
    Keywords:  autophagy; bibliometric analysis; orthodontic tooth movement; periodontal diseases; periodontal treatment efficacy
    DOI:  https://doi.org/10.3389/fmed.2025.1493459
  38. J Pediatr Soc North Am. 2024 Nov;9 100072
    Pediatric Orthopaedic Studies Published Open Access are Associated with Increased Citation Rates.
    Sreetha Sidharthan, Grace Wang, Erikson Nichols, Peter Cirrincione, Jonathan M Schachne, Colleen Wixted, Caitlin Penny, Keza Levine, Akshitha Adhiyaman, Joseph T Nguyen, Emily Dodwell.
       Background: Open access (OA) articles are freely accessible online, either on the publisher/journal website or in a repository, a publicly available, free-of-charge online database. The primary aim of this study was to investigate whether OA publication confers a citation advantage in pediatric orthopaedics.
    Methods: Pediatric orthopaedic studies published in English from January 1, 2012 to June 30, 2012 were identified through Excerpta medica database , Cochrane, and PubMed. Abstract screening and full-text evaluation were performed in duplicate. Citation counts over 10 years following publication, 2012 journal impact factor, OA status, type of OA, journal field, geographic location of senior author and journal publication, study design, study focus, subspecialty, level of evidence, and presence of funding were recorded. Statistical analyses were performed using independent samples t-tests, 1-way analysis of variance, χ2 tests, and multiple regression analysis.
    Results: Of this study's 989 pediatric orthopaedic articles, 43.8% were OA. The mean citation count was 19.8 ± 24.4 on Web of Science. Compared to OA publications, the highest percentage of non-OA articles were published in a journal from North America, had a senior author from North America, were indexed in Journal Citation Reports, and were published in orthopaedic journals (P < .001). In multiple regression analysis, OA publication, higher levels of evidence, publication in a journal with a higher impact factor, having a senior author from Europe or North America, and study funding were associated with significantly increased citation counts. OA articles were cited an additional 3 times, on average, over 10 years.
    Conclusions: Open access publication in pediatric orthopaedics confers an advantage of 3 extra citations over a decade, on average.
    Key Concepts: (1)Publishing pediatric orthopaedic articles open access confers an advantage of 3 additional citations over a decade compared to non-open access publication.(2)43.8% of pediatric orthopaedic articles are published open access.
    Level of Evidence: III.
    Keywords:  Citation rate; Open access; Publication trends
    DOI:  https://doi.org/10.1016/j.jposna.2024.100072
  39. Int Ophthalmol. 2025 May 26. 45(1): 210
    Global research trends on endoplasmic reticulum stress in retinal diseases from 2000 to 2024.
    Weiwen Hu, Yahan Tu, Jian Tan, Yeting Lin, Yicang Wang, Qiong Zhou.
       PURPOSE: To comprehensively explore global research trends on endoplasmic reticulum stress (ERS) in retinal diseases over the past 24 years.
    METHODS: An analysis of 917 publications from the Web of Science Core Collection, spanning from 1 January 2000 to 15 April 2024, was conducted to explore ERS research in retinal diseases. Bibliometric and visualisation software was employed to identify key contributors and research trends.
    RESULTS: Hideaki Hara and Sarah X. Zhang were identified as the most published and most cited authors, respectively. The United States led in both publications and citations. Sun Yat-sen University ranked highest in publications, while the University of Oklahoma received the most citations. Investigative Ophthalmology & Visual Science was the leading journal in both publications and citations. A total of 108 of the 1385 author keywords, each occurring five or more times, clustered into four major themes: retinal photoreceptor degeneration, glaucoma and optic nerve damage, diabetic retinopathy and age-related macular degeneration. Keywords such as "in vivo", "dominant retinitis pigmentosa", "endothelial growth factor", "molecular", and "quality control" displayed the strongest citation bursts. ERS research (2000 ~ 2024) has evolved from retinal neuroprotection to include specific cell types and diseases, explored signalling pathways and therapeutic mechanisms, and more recently has focused on molecular insights and gene therapy applications.
    CONCLUSION: This bibliometric analysis highlighted significant growth in publications on ERS in retinal diseases, reflecting an increasing scholarly focus. ERS represents a potential target for exploring pathological changes in retinal neuro-microvascular and related disorders, warranting further investigation.
    Keywords:  Bibliometric analysis; Diabetic retinopathy; Endoplasmic reticulum stress; Research trends; Retinal diseases
    DOI:  https://doi.org/10.1007/s10792-025-03584-5
  40. Malays J Med Sci. 2025 Feb;32(1): 35-55
    Bibliometric Analysis of The Global Research Trends on The Application of Tamoxifen in The Treatment of Breast Cancer Over The Past 50 Years.
    Ninie Nadia Zulkipli, Rahimah Zakaria, Wan Rohani Wan Taib.
      GLOBOCAN 2022 reported that breast cancer is a primary contributor to the incidence and mortality rates of cancer in women. The very high and low Human Development Index (HDI) tiers are the primary contributors to the highest incidence and mortality rates, respectively. This study aimed to provide a comprehensive landscape overview of trends, dynamics, and research hot spots on the application of tamoxifen in treating breast cancer over the past 50 years. We retrieved data from the Scopus database, spanning from 1973 to 2022. We utilised Microsoft Excel, Harzing's Publish or Perish, and VOSviewer to perform exhaustive analyses, including the publication trend, co-authorship, co-citation, co-occurrence of authors, organisations, countries, and keywords. A total of 3,721 publications fit the inclusion and exclusion criteria. Jordan VC was the most prominent author, making substantial contributions to the research topic. Erasmus MC was the most prolific organisation, while the Swiss Group for Clinical Cancer Research exhibited the most robust international collaboration. The United States and the United Kingdom consistently have the highest publication, TLS, and h- and g-indices. Using keyword co-occurrence analysis, we identify adjuvant endocrine therapy, postmenopausal, EGFR, HER2, and autophagy as research hot spots. For the past five decades, the research output of the application of tamoxifen in breast cancer treatment has exhibited an upward trend. This endeavour provides a crucial reference for researchers to direct greater attention toward research hot spots in the hope that it will improve breast cancer patients' treatments and, consequently, increase their survival rate.
    Keywords:  Harzing’s Publish or Perish; Scopus; VOSviewer; bibliometric analysis; breast cancer; tamoxifen
    DOI:  https://doi.org/10.21315/mjms-06-2024-452
  41. J Multidiscip Healthc. 2025 ;18 2875-2887
    A Bibliometric Analysis of Medication Compliance in Children with Asthma.
    Jing Zhao, Yu Ding, Zhiyuan Wang, Guo Kou, Sen Xu, Jing Tai, Chunrui Zhang, Ying Guo, Jun Yang.
       Objective: Bibliometrics was used to visualize the literature data of the current study on medication compliance in children with asthma, which can provide reference for improving the medication compliance of children with asthma.
    Methods: Using the bibliometrix package in R4.4.1, all the research literatures related to the medication compliance of children with asthma in the WOS core database were used, and the data visualization analysis of the retrieved research literatures was carried out.
    Results: A total of 285 research literatures on medication compliance in children with asthma were screened out. The earliest related research was published in 2009, and reaching its peak in 2019. The number of publications and citations related to medication compliance in children with asthma in the United States ranked first. J Allergy Clin Immun has 1043 citations in related journals. The analysis of cumulative publication volume shows that from 2009 to 2024, Journal of Asthma has the largest cumulative publication volume. Halterman Js is the most authoritative. The most frequently used keyword in these articles is "asthma". Statistical analysis of the high-frequency keywords in the literature on medication compliance in children with asthma showed that the top three high-frequency words were medication adherence, followed by unplanned children and childhood asthma.
    Conclusion: The study on medication compliance in children with asthma was first published in 2009, and the research heat increased year by year. The most authoritative author in the field of medication compliance in children with asthma is Halterman Js. Journal of Asthma magazine is interested in the research field of medication compliance in children with asthma.
    Keywords:  asthma; bibliometrics; children; medication adherence
    DOI:  https://doi.org/10.2147/JMDH.S514612
  42. Urology. 2025 May 24. pii: S0090-4295(25)00502-3. [Epub ahead of print]
    Beyond citations: exploring gender and racial gaps in urology publications through citation and Altmetric analysis.
    Betty Wang, Devika Nandwana, Emma Helstrom, Laura E Davis, Kirtishri Mishra, Rebecca Campbell, Salvador Jaime-Casas, Mohit Sindhani, Andres Correa, Adam Calaway, Christopher Weight, Laura Bukavina.
       OBJECTIVES: To examine the effects of author gender and race on citation metrics, including Altmetric Attention Scores (AAS), in urology publications.
    METHODS: We analyzed 91,100 urology publications published between 2009 and 2023, retrieved from the Altmetric database via Drexel University. Author gender was identified using GenderGuesser, and race was estimated using a published name-based algorithm. Publications were grouped by the gender of the first and last authors (e.g., MF: male first, female last). We compared AAS and calculated the Mean Citation Difference (MCD) to measure citation disparities against gender- and race-neutral models.
    RESULTS: Publications with male first and last authors (MM) comprised 44%, while female-female (FF) authorship accounted for only 6% of all publications. FF-authored studies were the most under-cited (MCD: -1.9), whereas FM-authored studies were the most over-cited (+2.53). Although female-authored papers had higher AAS scores, they remained under-cited across most urologic subspecialties. Racial disparities in citation metrics were less pronounced than those related to gender, and AAS differences between racial groups were not statistically significant.
    CONCLUSIONS: Publications authored by female first and last authors continue to be under-cited despite receiving higher AAS scores, and funding. In contrast, racial citation disparities appear to be minimal. These findings highlight the need to address gender-based inequities in academic recognition, as doing so may foster a more inclusive academic environment and ultimately improve access to equitable patient care.
    PATIENT SUMMARY: This study examined how often urology research papers are cited based on the gender and race of the authors. We found that studies led by women are cited less frequently than those led by men, despite receiving more online attention and funding. These findings underscore the need for fairer recognition of all researchers, as greater equity in academic publishing may help promote more inclusive and accessible patient care.
    DOI:  https://doi.org/10.1016/j.urology.2025.05.042
  43. J Transcult Nurs. 2025 May 27. 10436596251340621
    Global Trends and Hot Topics in Nursing Studies on Immigrants: A Retrospective Bibliometric Analysis From 1975 to 2024.
    Ayla Tuzcu İnce, Ayla Kaya.
       INTRODUCTION: This study is unique in that it is the first bibliometric analysis study addressing nursing studies on immigrants. This study aimed to evaluate global trends and current issues in the 49-year history of nursing studies on immigrants.
    METHOD: This retrospective bibliometric analysis study was conducted with 832 data obtained from the WoSCC database on March 11, 2024. Bibliometrix Package in R software, VOSviewer, and WoSCC were used for data analysis.
    RESULTS: The research findings were evidence that immigrant-related nursing studies were growing rapidly in the scientific world. While the most productive journal was the Journal of Transcultural Nursing, the most productive and collaborative country was the United States. "Refugees," "qualitative," "health disparities," "health literacy," and "mental health" were determined as hot topics in the field. "COVID-19" and "migrant" were global trends.
    DISCUSSION: For studies to be planned regarding immigrants, nursing researchers can take into account the results of this study.
    Keywords:  bibliometrics analysis; immigrants; migrants; nursing
    DOI:  https://doi.org/10.1177/10436596251340621
  44. Front Nutr. 2025 ;12 1550142
    Nutritional composition and health benefits of peas-a bibliometric research.
    Melekşen Akin, Sadiye Peral Eyduran, Jelena Mileševic, Suzana Pavlovic, Amil Orahovac, Marta W Vasconcelos, Marija Knez.
      Pea (Pisum sativum L.) is a nutritious legume with health benefits, gaining attention as a functional food. Bibliometric studies use quantitative methods to assess research trends, gaps, and future directions. The main objective of this study was to provide a comprehensive overview of the fragmented literature on the nutritional profiles and health benefits of peas using a bibliometric approach. The analysis examined publications from 2013 to 2023, revealing trends in publication volume, author productivity, and international collaboration. Publications peaked in 2015, focusing on topics such as dietary fibers, carotenoids, phenolic compounds, and antinutrients affecting mineral bioavailability. Over the decade, the annual growth rate was 3.25%. The University of Saskatchewan produced the most influential research, with Warkentin TD as the most productive author. Canada and Poland had the highest number of publications, with the USA, China, and India following. Six major international co-authorship networks were identified, highlighting significant collaborations between countries. Key research themes included antioxidants, protein, fiber, and phytate in peas. This study provides a strong foundation for future integrated research, helping to better understand the potential of peas as a functional food and guiding more targeted studies to address current knowledge gaps across various disciplines.
    Keywords:  Pisum sativum; analysis; network analysis; performance analysis; science mapping
    DOI:  https://doi.org/10.3389/fnut.2025.1550142
  45. Front Med (Lausanne). 2025 ;12 1535189
    The present and future of geriatric internal medicine: a bibliometric analysis.
    Yingjie Chen, Xiuli Dong, Yan Jia.
      With the gradual progress of global aging, geriatric medicine is becoming increasingly popular, and within geriatric medicine, internal medicine holds a very important position. Understanding the situation in the field of geriatric internal medicine helps researchers gain a comprehensive understanding of this area. In this study, we analyzed and visualized relevant literature from the Web of Science Core Collection database using bibliometric methods, collecting a total of 831 articles, with a time span from 1978 to August 2024. We analyzed the overview of the field, the degree of aging and the volume of publications by country, the core journals in the field, the collaboration relationships among institutions and authors, as well as the hotspots and their changes, and discussed the results. This study provides a broad perspective for professionals in the field of geriatric internal medicine and discusses the future research development in the field.
    Keywords:  VOSviewer; bibliometrics; geriatric internal medicine; geriatrics; internal medicine
    DOI:  https://doi.org/10.3389/fmed.2025.1535189
  46. World J Urol. 2025 May 30. 43(1): 339
    Visualized bibliometric panorama of ureteral stents (1975-present): trends and hotspots revealed.
    Renjie Wei, Fudong Liu, Xinjie Ji, Xu Luo, Chunyu Gong, Ruitu Ran.
      Ureteral stent (US) is vital in managing ureteral obstruction, ensuring drainage, and providing structural support. Despite extensive research, a comprehensive synthesis of findings is lacking. This study employs bibliometric analysis and visualization tools to examine 2,994 articles from the Web of Science (1975-2024), identifying key researchers, institutions, countries, and trends. Results indicate a rising publication trend, particularly in the last five years, with the United States leading in output and centrality. The University of California System emerged as the top institution. Key journals and bridging keywords such as "complication" and "ureteral obstruction" (centrality > 0.1) highlight critical research areas, including surgical interventions, iatrogenic injury, and stent failure. Clustering revealed hotspots such as intrarenal surgery, ureteropelvic junction obstruction, stent-related symptoms, and benign ureteral obstruction. Current research focuses on guideline development, outcome evaluation, prevalence studies, and complications such as sepsis. This analysis provides insights into US research trends, guiding future innovation and topic selection in the field.
    Keywords:  Bibliometrics; Hotspots; Ureteral obstruction; Ureteral stent; Visualization
    DOI:  https://doi.org/10.1007/s00345-025-05723-0
  47. Lab Anim. 2025 May 30. 236772251332567
    Compassion fatigue in laboratory animal personnel: a bibliometric analysis of global trends.
    John K Chipangura.
      Laboratory animal personnel face enormous pressures such as workload, conflicts, deadlines, lack of psychological support, and ethical dilemmas. These pressures are often due to the need to balance scientific objectives, ethical responsibilities, and personal emotions, while trying to maintain legal and institutional animal housing and care standards. When these profession-related pressures are exacerbated by toxic social relationships and financial challenges, it may lead to chronic stress that will ultimately cause compassion fatigue. This review aimed to analyse publication trends on compassion fatigue among laboratory animal personnel by undertaking a bibliometric analysis of published articles to produce insights that could inform future research strategies. A literature search was carried out via the Scopus databases for articles published in English. The data collected from the search was transferred to the Bibliometrix R-package and assessed for publication trends, analysis of contributing countries, thematic evolution, and the co-occurrence of authors' keywords. Seventeen articles published between 2015 and 2024 were retrieved for analysis. Among these, 14 were survey studies and 3 were literature reviews. The number of articles published is on an upward trend, with all authors being affiliated with Global North institutions. The keyword analysis identified 53 words. The most common term used was 'compassion fatigue' (CF) and the analysis indicated that technicians and veterinarians are the primary target populations for CF research. The modest rise in the body of literature on CF and mental health issues among laboratory animal personnel is commendable and I encourage more work to be done to better understand this complex phenomenon.
    Keywords:  Laboratory animals; bibliometric analysis; compassion fatigue; global trends; laboratory animal personnel
    DOI:  https://doi.org/10.1177/00236772251332567
  48. J Affect Disord. 2025 May 27. pii: S0165-0327(25)00927-9. [Epub ahead of print]387 119485
    A scientometric analysis of machine learning in schizophrenia neuroimaging: Trends and insights (2012-2024).
    Xingsong Wang, Xiaoqun Chen, Miaomiao Yan, Li Kong.
      Machine learning applications in schizophrenia neuroimaging research have undergone significant evolution since 2012. However, a comprehensive scientometric analysis of this field has not yet been conducted. This study analyzed 315 original research articles, accumulating 10,181 citations, from the Web of Science Core Collection (WOSCC) (2012-2024) using R-bibliometrix and CiteSpace. The annual publication output showed steady growth, reaching a peak of 57 publications in 2021, followed by a gradual decline. Network analysis revealed a thematic evolution from conventional machine learning applications toward explainable artificial intelligence, and a methodlogical shift from single-modality imaging to integrated multimodal approaches (modularity Q = 0.7536, silhouette S = 0.9039). China led in publication count (115), whereas the United States had the highest citation impact (4414 citations). Recent research clusters (2021-2024) highlighted areas such as risk assessment, brain age prediction, and treatment response monitoring. These findings provide strategic guidance for future research directions in neuroimaging-based machine learning applications for schizophrenia, emphasizing the critical need for methodological standardization to enhance clinical application.
    Keywords:  Clinical translation; Machine learning; Neuroimaging; Research trends; Schizophrenia; Scientometric analysis
    DOI:  https://doi.org/10.1016/j.jad.2025.119485
  49. Discov Oncol. 2025 May 24. 16(1): 911
    Global research trends on the links between prostate cancer and postoperative urinary incontinence between 2014 and 2024: a bibliometrics and visualized study.
    FuQiang Li, DeSheng Zhu, QingHong Li, ZhiLong Zhong, WenTao Fan, Zekun Xu.
      In recent years, the incidence of prostate cancer (PC) has increased. For patients suitable for surgery, surgical treatment is undoubtedly the first-choice. However, radical prostatectomy often leads to postoperative urinary incontinence. As a result, the issue of urinary incontinence following prostate cancer treatment has also come into focus. However, comprehensive and objective research on the overall state of UI after PC treatment remains scarce. This article aims to utilize bibliometrics to summarize and quantify the dynamic trends of UI in PC. We retrieved relevant literature on PC and UI from the Web of Science Core Collection database, spanning from January 1, 2014, to September 8, 2024, and analyzed bibliometric indicators such as the number of articles, journals, countries, institutions, authors, and keywords. A total of 2060 articles were included, and the study shows a continuous growth in the number of publications related to PC and UI, with the United States leading in this field. The Memorial Sloan Kettering Cancer Center is the institution with the highest research output, the journal "Urology" published the most articles, and author Matthew R Cooperberg has the highest research output. We recommend active collaboration between countries, institutions, and authors to conduct clinical and basic research. Keyword analysis indicates that current research is primarily focused on side effects following PC treatment, the application of artificial urinary sphincters, and the application of multiparametric magnetic resonance imaging in the field of PC and UI. We anticipate that side effects caused by PC treatment will continue to be a hot topic in future research. It has to be admitted that our study only included English literature in the Web of Science database, and there may be some selection bias.
    Keywords:  Bibliometrics; Prostate cancer; Radical prostatectomy; Urinary incontinence
    DOI:  https://doi.org/10.1007/s12672-025-02749-z
  50. Discov Oncol. 2025 May 26. 16(1): 928
    Disclosing the development and focus of sequencing and omics studies in kidney neoplasm research.
    Yifan Liu, Bingnan Lu, Xinyue Yang, Jinming Cui, Tianyue Yang, Haoyu Zhang, Zihui Zhao, Donghao Lyu, Yuanan Li, Yuntao Yao, Runzhi Huang, Xiuwu Pan.
       BACKGROUND: Kidney cancer is a worldwide prevalent urological malignancy and the leading cause of death. Sequencing and omics studies play a crucial role in unraveling its molecular mechanisms and diagnostic, prognostic, and therapeutic relevance. This study aims to offer a comprehensive review of the evolving trends and hotspots of sequencing and omics studies in kidney neoplasms.
    METHODS: We conducted the retrieval of scientific publications on sequencing and omics studies in kidney neoplasms from the Web of Science Core Collection (WoSCC) on July 3, 2023. The R-based bibliometrix package, VOSviewer, and CiteSpace were utilized to conduct the holistic bibliometric analysis to obtain objective and data-driven results. A comprehensive consultation of papers was then proceeded for an in-depth review.
    RESULTS: Our investigation yielded a dataset containing 1260 records from 509 sources, with 43,404 references, from 1960 to 2023. Publication and citation frequencies have been consistently growing. In country analysis, China and the USA led the research, displaying substantial collaboration. Notable contributors like TEH BT, SAUTER G, and FUTREAL PA shaped this research landscape. Key journals such as PLoS One, Cancer Research, and New England Journal of Medicine actively participated in and significantly influenced this field. Distinguished publications and references were also revealed, along with their historical citation and co-citation relationships. A panel of keywords, including RCC, biomarker, and multi-omics data were identified and clustered.
    CONCLUSION: We obtained a profound understanding of the developing trends and hotspots of research investigating sequencing and omics studies in kidney neoplasms. Specifically, we have highlighted three hotspots: "explore molecular mechanisms of RCC pathogenesis, progression, and metastasis", "identify molecular biomarkers of RCC for diagnosis, prognosis, and therapeutics", "investigate tumor heterogeneity and tailor personalized therapeutic strategies for RCC". Hopefully, our study will serve as a valuable reference for scientific researchers and clinical practitioners.
    Keywords:  Bibliometrics; Genomics; Kidney cancer; Kidney neoplasm; Metabolomics; Omics; Proteomics; Renal cell carcinoma (RCC); Sequencing; Transcriptomics
    DOI:  https://doi.org/10.1007/s12672-025-02750-6
  51. Asia Pac J Clin Nutr. 2025 Jun;34(3): 271-281
    Global trends and hotspots in nutritional risk screening, assessment, and diagnosis: A bibliometric and visual analysis (1991-2024).
    Meidi Wang, Qianqian Li, Jing Wu, Mingyao Xu, Jia R Yue, Weiwei W Cui.
       BACKGROUND AND OBJECTIVES: Nutrition is important in promoting health and preventing disease, while malnutrition can exacerbate disease symptoms and lead to adverse clinical outcomes in patients. The process of nutritional diagnosis and treatment includes nutritional risk screening, nutritional assessment, and nutritional therapy. This study aims to understand the number of publications, cooperation of research subjects, progress of research content, and research hotspots of nutritional risk screening and assessment, and then identify the future trends and directions of global nutritional screening.
    METHODS AND STUDY DESIGN: Articles on nutritional risk screening, nutritional assessment and application of nutritional diagnostic tools were identified from the Web of Science and the collected data were analysed using bibliometrics and information visualisa-tion with the help of CiteSpace software. A total of 10632 articles published between 1991 and 2024 were selected.
    RESULTS: The country with the highest number of articles was the United States; two institutions, the University of São Paulo and the Karolinska Institutet, had higher centrality and number of articles. Keyword emergent analysis revealed that global leadership initiatives on malnutrition, diagnosis, criteria, myasthenia gravis, and clinical nutrition were the five emergent terms that lasted until 2024 and were the most popular hot topics among experts and scholars.
    CONCLUSIONS: We describe the characteristics of the development of nutritional risk screening and assessment studies and their trends. Currently, there is not a close collaboration between institutions and authors in the research process, while the field is trending towards more specific research and a greater focus on the disease progression in patients.
    Keywords:   CiteSpace; visual analytics; nutritional assessment; nutritional diagnosis tools; nutritional risk screening
    DOI:  https://doi.org/10.6133/apjcn.202506_34(3).0002
  52. Clin Res Hepatol Gastroenterol. 2025 May 26. pii: S2210-7401(25)00108-1. [Epub ahead of print] 102630
    Analysis of article types of the top-100 cited articles on gastrointestinal endoscopy.
    Yanqing Song, Lei Deng, Yanhua Peng, Rui Zhou.
      
    Keywords:  bibliometric analysis; clinical trials; gastrointestinal endoscopy
    DOI:  https://doi.org/10.1016/j.clinre.2025.102630
  53. Eur J Dent Educ. 2025 May 29.
    Global Trends in the Use of Artificial Intelligence in Dental Education: A Bibliometric Analysis.
    Margarita Iniesta, Juan José Pérez-Higueras.
       INTRODUCTION: The aim of this study was to examine the application of artificial intelligence (AI) and generative AI (GAI) in dental education through a comprehensive bibliometric analysis, with the goal of identifying potential future research areas in this field.
    MATERIALS AND METHODS: Data were obtained from the Web of Science and Scopus databases, with no date restrictions. The inclusion criteria encompassed research articles, reviews and proceedings papers focused on the use of AI in dental education. The Bibliometrix R package was used for data analysis.
    RESULTS: A total of 54 documents were analysed, revealing a significant increase in publications from 2021 to 2024. The Journal of Dental Education was identified as the most prolific source, with the United States leading in terms of contributions. The findings showed a growing interest in AI's potential to transform dental education, with significant contributions from a diverse set of global authors and institutions. Several key themes were identified, including 'large language models', 'chatbots' and 'clinical decision support systems'. The citation analysis highlighted influential papers, including those by Thurzo et al. (2023) and Yüzbaşıoğlu (2021).
    CONCLUSION: There is a growing interest in the use of AI and GAI in dental education. However, further research, particularly experimental studies, is essential to fully understand their impact on educational outcomes in dentistry. Key areas for exploration include the application of AI for personalised learning, the integration of chatbots as educational tools to support students, and the use of AI for training and assessing practical skills.
    Keywords:  artificial intelligence; bibliometric analysis; dental education; generative artificial intelligence
    DOI:  https://doi.org/10.1111/eje.13133
  54. Probiotics Antimicrob Proteins. 2025 May 28.
    Data-Driven Visualization of the Dynamics of Antimicrobial Peptides in Cell Death.
    Dan Hou, Jiatong Zhao, Mingshi Guo, Xinran Zhang, Shuiqing Yu, Jiayue Li, Tymour Forouzanfar, Qing Zhang, Janak L Pathak.
      This study explores the current status, research hotspots, and emerging trends in AMP-induced cell death through bibliometric and data-driven visual analysis. The findings aim to provide researchers and clinical professionals with new insights and potential research directions. A total of 1,897 articles and reviews published between 2006 and 2024 were retrieved from the Web of Science Core Collection. Bibliometric and visual analyses were conducted using CiteSpace, VOSviewer, Scimago Graphica, Origin 2022, and WordClouds. The analysis focused on publication trends, contributing institutions, journals, authors, cited references, and keywords. China contributed the largest share of publications (28.15%). The Chinese Academy of Sciences emerged as the most collaborative institution, demonstrating the highest centrality. The author with the highest composite index was Chen, Jyh-Yih (2,985.27). Recent research hotspots have centered on elucidating the mechanisms of AMP-induced cell death and exploring the potential applications of AMPs in cancer therapy. Keywords such as anticancer peptides, mechanism, design, and antibiotic resistance currently dominate the field, reflecting its evolving focus. Research on the application of AMPs in cancer treatment is gaining momentum. The forefront of this field involves modifying and designing AMPs to address antibiotic-resistant bacterial infections and advance cancer therapeutics. However, further investigation is needed to uncover the specific molecular mechanisms underlying AMP-induced cell death, including necrosis, pyroptosis, and ferroptosis.
    Keywords:  Antimicrobial peptides; Bibliometrics; Cancer; Cell death; Mechanism; Visualization analysis
    DOI:  https://doi.org/10.1007/s12602-025-10578-3
  55. Front Oncol. 2025 ;15 1502361
    Chemotherapy cardiotoxicity research in cancer patients: a bibliometric and visual analysis (1994-2024).
    Guoming Chen, Huiping Zhou, Chengbin Wang, Rui Qin, Qingyi Yang, Yingyue Hou, Meizhen Zhang, Cheng Zhang, Ning Wang, Yibin Feng.
       Background: Recent advancements in medical technology have significantly boosted the survival rates of cancer patients. The potential toxicities that cancer treatments may induce in other areas of the human body have garnered increasing attention. Chemotherapy, a pivotal component of anticancer therapy, heightens the risk of cardiac damage and contributes to various cardiovascular complications. To comprehensively assess the research landscape concerning chemotherapy-induced cardiotoxicity in cancer patients, this study conducted a visual analysis of pertinent articles utilizing bibliometric tools.
    Method: We used CiteSpace, VOSviewer, to analyze the temporal and spatial distribution, disciplinary categories, authorship, references, subject terms, and keywords of 4460 articles retrieved from the Web of Science core collection from 1994 to January 21, 2024.
    Results: Contributions to this field emanated from 100 countries/regions and 4,343 research institutions, with the United States, China, and Italy emerging as the most prolific contributors in terms of publication volume. The Journal of Clinical Oncology emerged as the primary journal in terms of publications and co-citations within this domain, with Bonnie Ky identified as the most prolific author. Common keywords included breast cancer, doxorubicin, heart failure, trial, adjuvant chemotherapy, paclitaxel, and risk. Terms such as echocardiography, nanoparticles, mechanisms, prevention, society, oxidative stress, inflammation, consensus, and global longitudinal strain delineated the current research frontier in this field. Additionally, the study provided a detailed examination of the fundamental aspects of research in this domain. Presently, key research focuses in this area include elucidating the mechanisms of chemotherapy-induced cardiotoxicity, monitoring and evaluating such cardiotoxicity, and developing strategies for its prevention and treatment.
    Conclusion: This study provides a comprehensive overview of chemotherapy-induced cardiotoxicity research from 1994 to 2024. Future research should prioritize personalized risk assessment and interdisciplinary collaboration to meet the clinical needs of the cardiovascular oncology field.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; cancer; cardiotoxicity; chemotherapy
    DOI:  https://doi.org/10.3389/fonc.2025.1502361
  56. Healthcare (Basel). 2025 May 15. pii: 1149. [Epub ahead of print]13(10):
    Mapping Research Trends on the Implications of Telemedicine for Healthcare Professionals: A Comprehensive Bibliometric Analysis.
    Chiara Bernuzzi, Maria Adele Piccardo, Chiara Guglielmetti.
      Background/Objectives: The digital transformation in healthcare is reshaping care delivery by enhancing patient care and flexibility. However, it also poses potential challenges to healthcare professionals' wellbeing and work practices. To date, research on the implications of telemedicine for healthcare professionals remains limited and inconclusive. This study aims to provide a comprehensive overview of this research field using a quantitative, bibliometric approach. Methods: Articles were systematically selected from Web of Science and Scopus databases, focusing on empirical, peer-reviewed articles written in English, involving healthcare professionals and focusing on telemedicine. Results: The dataset consists of 160 papers. The analysis reveals a significant increase in publications starting from 2012, with a notable surge in 2020, reflecting the impact of the COVID-19 pandemic. The University of New Mexico and the Cleveland Clinic Foundation, both in the United States, were identified as the institutions with the highest number of published articles. Most studies were published in clinical-focused journals (e.g., Journal of Medical Internet Research and BMC Health Services Research), emphasizing the field's dominant orientation. The intellectual structure reveals that wellbeing, work practices, and communications between patients and professionals are central themes. Conclusions: This bibliometric analysis provides scholars with a clearer understanding of the intellectual structure of research on the implications of telemedicine for healthcare professionals, addressing key gaps left by previous reviews. While telemedicine offers numerous advantages, such as enhanced access to care and greater flexibility, it also raises challenges related to healthcare professionals' wellbeing, work practices, and communication with patients. Both contextual factors (e.g., digital skills training) and individual characteristics (e.g., attitudes toward telemedicine) play a significant role in shaping healthcare professionals' experiences with telemedicine. By identifying influential contributors and thematic patterns, this study offers a foundation for future research and informs the development of targeted interventions to sustain healthcare professionals in digitally mediated care environments.
    Keywords:  bibliometric analysis; healthcare professionals; telemedicine; wellbeing; work outcomes
    DOI:  https://doi.org/10.3390/healthcare13101149
  57. Microorganisms. 2025 May 12. pii: 1110. [Epub ahead of print]13(5):
    Microorganisms in Macroalgae Cultivation Ecosystems: A Systematic Review and Future Prospects Based on Bibliometric Analysis.
    Yinglong Chen, Pengbing Pei, Muhammad Aslam, Muhamad Syaifudin, Ran Bi, Ping Li, Hong Du.
      Microorganisms play an essential role in the biogeochemical processes of macroalgal cultivation ecosystems by participating in a complex network of interactions, significantly influencing the growth and development of macroalgae. This study used bibliometric analysis and VOSviewer based on Web of Science data to provide an overview by tracing the developmental footprint of the technology. Countries, institutions, authors, keywords, and key phrases were tracked and mapped accordingly. From 1 January 2003 to 31 December 2023, 619 documents by 2516 authors from 716 institutions in 51 countries were analyzed. Keyword co-occurrence network analysis revealed five main areas of research on microbes in macroalgal cultivation ecosystems: (1) identification of microbial species and functional genes, (2) biogeochemical cycling of carbon in microbial communities, (3) microbial influences on macroalgae growth and development, (4) bioactivities, and (5) studies based on database. Thematic evolution and map research emphasized the centrality of microbial diversity research in this direction. Over time, the research hotspots and the core scientific questions of the microorganisms in the macroalgal cultivation ecosystems have evolved from single-organism interactions to the complex dynamics of microbial communities. The application of high-throughput techniques had become a hotspot, and the adoption of systems biology approaches had further facilitated the integrated analysis of microbial community composition and function. Our results provide valuable guidance and information for future researches on algal-bacterial interactions and microbe-driven carbon cycling in coastal ecosystems.
    Keywords:  bibliometric analysis; biogeochemical cycling of carbon; functional genes; macroalgal cultivation environment; microorganisms
    DOI:  https://doi.org/10.3390/microorganisms13051110
  58. Ann Fam Med. 2025 May 27. 23(3): 223-230
    Authorship Inequity in Global Health Research Conducted in Low- and Middle-Income Countries and Published in High-Income Country Family Medicine Journals.
    Alyssa Vecchio, Bridget Nandawula, Kelsey Sawyer, James Akiruga Amisi, Daria Szkwarko, Kathy Z Chang.
       PURPOSE: The current structures of global health research and academic authorship have resulted in underrepresentation of authors from low- and middle-income countries. Although authorship inequity has been shown in other specialties, the current status of authorship in family medicine has not been examined.
    METHODS: We conducted a bibliometric analysis of World Organization of Family Doctors (WONCA) journals based in high-income countries for articles describing research conducted in low-income countries, lower-middle-income countries, and upper-middle-income countries from 2018 to 2023. Descriptive statistics were computed to summarize the proportion of first and senior authors by the articles' study location and publication characteristics.
    RESULTS: We retrieved 1,030 articles through our comprehensive search. A total of 431 articles from 16 family medicine journals remained after abstract and full-text review. Over time, there was an increase in publication of research articles from low- and middle-income countries in the family medicine journals, with the majority of the studies conducted in upper-middle-income countries (55.9%). The proportion of senior authors from high-income countries was highest in articles with research conducted in low-income countries (50%) compared with those reporting research done in lower-middle-income countries (37%) and upper-middle-income countries (21%).
    CONCLUSIONS: About one-quarter of articles with research conducted in low- and middle-income countries and published in family medicine journals have first and/or senior authors from high-income countries; this representation is even higher when analysis is restricted to research done in low-income countries. To support authorship equity, family medicine researchers should reconsider the definition of authorship criteria, promote culturally humble mentorship, and encourage institutions to adapt promotion criteria to empower equitable global health partnerships.
    Keywords:  authorship equity; developed country; developing country; family practice; global health; global health research; international cooperation; low-middle-income countries; medical journals; primary care; publications
    DOI:  https://doi.org/10.1370/afm.240431
  59. Front Psychol. 2025 ;16 1560467
    Connecting urban green and blue spaces with children' health: a bibliometric analysis in CiteSpace and VOSviewer.
    Yutong Kang, Zhengbing Guo.
       Introduction: Rapid urbanization has increasingly restricted children's access to natural environments, raising concerns about potential consequences for their physical, mental, and social well-being. Urban green and blue spaces are known to offer significant health benefits, including physical activity promotion, psychological restoration, and social development.
    Methods: This study conducted a comprehensive bibliometric analysis to examine the relationship between urban green/blue spaces and children's health. A total of 575 relevant publications from 1981 to 2024 were retrieved from the Web of Science database. CiteSpace and VOSviewer were used for keyword co-occurrence analysis, co-citation mapping, and burst detection to visualize research trends and thematic evolution.
    Results: Three major research phases were identified: (1) early focus on physical health outcomes, (2) a shift toward urban environmental contexts, and (3) emerging emphasis on sustainability, environmental quality, and walkability. While green spaces have been extensively studied, blue spaces remain underrepresented, especially in terms of their synergistic benefits when combined with green spaces. Key research themes include mental and physical health impacts, social skills development, and the educational functions of nature exposure.
    Discussion: This study reveals the interdisciplinary and collaborative nature of current research and emphasizes the importance of ensuring equitable access to high-quality natural environments in urban areas. The findings offer practical implications for urban planners and policymakers and establish a research foundation for promoting sustainable urban development that supports children's health and well-being.
    Keywords:  CiteSpace; VOSviewer; children’s health; urban blue space; urban green space
    DOI:  https://doi.org/10.3389/fpsyg.2025.1560467
  60. World Neurosurg. 2025 May 24. pii: S1878-8750(25)00476-0. [Epub ahead of print] 124120
    Letter to the Editor Regarding: Cerebrospinal Fluid Biomarkers in Idiopathic Normal Pressure Hydrocephalus: Bibliometric Analysis and Literature Review.
    Shoaib Majeed, Noshaba Majeed, Jie Tu.
      
    DOI:  https://doi.org/10.1016/j.wneu.2025.124120
  61. J Multidiscip Healthc. 2025 ;18 2799-2811
    Mapping Artificial Intelligence Research Trends in Critical Care Nursing: A Bibliometric Analysis.
    Li Zhou, Ke Geng, Chao Yu.
       Background: Recent development in AI-driven predictive analytics have demonstrated potential to enhance critical care workflows, particularly in three areas, including continuous vital sign monitoring in the ICU, intelligent nursing process management, AI-powered early risk stratification.
    Objective: This bibliometric study analyzes trends of artificial intelligence research in critical care nursing between 2013 and 2023 and provides future research directions.
    Results: The 1,346 relevant articles revealed a clear upward trajectory in research output related to AI in critical care nursing. The largest number of articles originated from the United States, followed by China, and the United Kingdom. Harvard University was the leading contributing institution, followed by the University of California and the Massachusetts Institute of Technology. Keyword clustering analysis generated seven representative cluster labels. Machine learning, AI, and deep learning were the major tools utilized during scholarly investigations of AI-driven research in critical care nursing.
    Discussion: Our findings shed light on the opportunities for AI to transform critical care nursing practice, particularly in optimizing ICU workflow efficiency, precision patient monitoring, and evidence-based decision acceleration.
    Conclusion: We advocate for the expansion of this type of research, the facilitation of collaboration among research institutions, and further development of international research collaborations.
    Keywords:  CiteSpace; artificial intelligence; critical care nursing; visualization
    DOI:  https://doi.org/10.2147/JMDH.S522731
  62. Scand J Public Health. 2025 May 24. 14034948251336851
    Household dysfunction and child outcomes in the Nordic countries: A bibliometric analysis.
    Rebecca L Radlick, Alice Milivinti, Håvard T Rydland, Ingrid R Lundeberg, Kristin G Askeland.
       AIMS: This article provides a bibliometric analysis of the literature on adverse childhood experiences (ACEs) related to household dysfunction (parents' substance abuse, physical or mental illness, death, criminality, and divorce/separation) in five Nordic countries. We identify: 1) main patterns and characteristics of the literature on household dysfunction ACEs and child outcomes; 2) highlight research gaps, topics and approaches for future inquiry on these ACEs.
    METHODS: A systematic search for peer-reviewed articles published from 1998 to 2022 in English was conducted in seven databases. Information from the articles was extracted using a coding matrix that included variables related to country, specific household dysfunction ACE(s) occurring before 18 years, child outcome(s), method, data source(s) and whether resilience or protective factors were assessed. Bibliometric analyses were used to summarize the literature patterns.
    RESULTS: A total of N=5003 publications were identified and n=342 publications were included in the analysis. n=112 publications studied two or more ACEs of interest. Divorce/separation was the most common individual ACE (n=97), whereas parental criminality was the least common (n=9). n=197 publications studied child mental health outcomes, whereas educational (n=41) and labour market (n=11) outcomes were less represented. Few (n=36) studies included protective factors.
    CONCLUSIONS: Our findings suggest a notable increase in research on household dysfunction adversities in the Nordic countries over the past two decades, focusing mainly on health-related outcomes. Future research should investigate less represented adversities, functional outcomes and protective factors. Interdisciplinary and new methodological approaches can provide fresh insights into this public health challenge.
    Keywords:  Adverse childhood experiences; household dysfunction; incarceration; labour market; mental health; parents; resilience; school completion; somatic health
    DOI:  https://doi.org/10.1177/14034948251336851
  63. Hum Vaccin Immunother. 2025 Dec;21(1): 2505349
    How has the field of immunogenic cell death in breast cancer evolved and impacted clinical practice over the past eleven years?
    Yu-Long Deng, Bang-Teng Chi, Shang-Yi Lu, Dan-Dan Xiong, Rong-Quan He, Di-Yuan Qin, Wan-Ying Huang, Xia Yang, Gang Chen, Wei Peng, Jiayuan Luo.
      This study elucidates the research landscape of immunogenic cell death (ICD) in breast cancer through a bibliometric analysis of 457 Web of Science articles. Contributions from China and the USA are particularly prominent, with notable international collaborations. Core journals such as Biomaterials published influential studies, while researchers like Huang Y made impactful contributions. High-frequency keyword analysis identified key research hotspots, including immunotherapy, the tumor microenvironment, and nanomedicine. The integration of chemotherapy with immunotherapy and the identification of key proteins have driven recent advancements. Fundamental research on immunotherapy, photodynamic therapy (PDT), and triple-negative breast cancer (TNBC) points to future trends and potential breakthroughs. This study offers a strategic overview of ICD in breast cancer, providing insights into clinical practice and guiding future research in the field.
    Keywords:  Breast cancer; bibliometric; clinical practice; immunogenic cell death; immunotherapy
    DOI:  https://doi.org/10.1080/21645515.2025.2505349
  64. Stem Cell Res Ther. 2025 May 28. 16(1): 259
    Research landscape and trends of human umbilical cord mesenchymal stem cell-derived exosomes.
    Desheng Chen, Zeping Chen, Jiabin Yuan, Guanzi Chen, Yutao Chen, Kaiming He, Yongwei Hu, Linsen Ye, Yang Yang.
       BACKGROUND: Human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) have gained significant attention for their potential in cellular regeneration and functional rehabilitation. Nevertheless, the rapid expansion of research in this field makes it challenging for emerging trends and strategic priorities, potentially impeding scientific advancement. This study employs bibliometric analysis to systematically evaluate the research landscape and highlight pivotal research trajectories of hUCMSC-Exos.
    METHODS: Publications on hUCMSC-Exos from 2012 to 2024 were retrieved from the Web of Science Core Collection (WoSCC). Quantitative bibliometric analysis was implemented through integrated utilization of VOSviewer, CiteSpace, and Bibliometrix analytical tools.
    RESULTS: China and its institutions led global publication output, with Qian Hui from Jiangsu University identified as the most prolific author. STEM CELL RESEARCH & THERAPY emerged as a high-impact journal in this domain. Current research predominantly focuses on immunomodulation, regenerative medicine, pharmaceutical delivery systems, and clinical model development. Future research directions are expected to explore angiogenesis, spinal cord injury, and immunomodulation.
    CONCLUSIONS: This study maps the evolving landscape of hUCMSC-Exos research, emphasizing its applications in regenerative medicine. By synthesizing current and emerging paradigms, these findings provide insights into therapeutic potential, novel mechanisms, and pathways for clinical translation.
    Keywords:  Angiogenesis; Bibliometric analysis; Exosomes; Human umbilical cord; Immunomodulation; Mesenchymal stem cell; Spinal cord injury
    DOI:  https://doi.org/10.1186/s13287-025-04379-2
  65. Issues Ment Health Nurs. 2025 May 28. 1-13
    Machine Learning and Artificial Intelligence in Suicide Prevention: A Bibliometric Analysis of Emerging Trends and Implications for Nursing.
    Erman Yıldız.
      Nurses play a crucial role in suicide prevention, yet the integration of artificial intelligence and machine learning technologies into nursing practice remains understudied. This research examines how these technologies can enhance nurses' ability to identify and intervene with at-risk patients. A systematic bibliometric analysis and thematic mapping approach was employed. The Web of Science database was searched for relevant publications from January 2019 to October 2024. The initial search yielded 883 publications, with 257 meeting the inclusion criteria after systematic screening. Analysis revealed six distinct research clusters, with machine learning-based behavioral prediction emerging as the dominant theme. Findings indicate significant potential for integrating artificial intelligence-supported tools into nursing workflows, particularly in risk assessment and early intervention. Natural language processing and ecological momentary assessment emerged as promising approaches for enhancing nurse-patient communication and monitoring. These findings suggest opportunities for nurses to leverage artificial intelligence technologies in suicide prevention while maintaining the essential human element of care. This study provides evidence-based guidance for nurses implementing artificial intelligence-supported suicide prevention tools while maintaining therapeutic relationships and professional judgment in clinical practice.
    DOI:  https://doi.org/10.1080/01612840.2025.2505904
  66. Mar Pollut Bull. 2025 May 23. pii: S0025-326X(25)00641-1. [Epub ahead of print]218 118166
    Progress analysis of multi-dimensional perspective research on green ships: A knowledge graph-based approach.
    Chunhui Zhou, Lin Jia, Wenjun Jia, Wuao Tang, Hongxun Huang, Lichuan Wu.
      With the increased global focus on environmental protection, green ships have emerged as the cornerstone to the maritime industry's long-term development. Based on the knowledge graph method, this paper uses bibliometric analysis to examine the research progress of green ships in a multidimensional perspective. Firstly, sort out the definition and connotation of green ships, and clarify their greening requirements in the whole life cycle. Bibliometric analysis of relevant literature using the bibliometrix package; secondly, combined with the virtual analysis method-VOSviewer software, it explores the current research status of green ships from the multi-dimensional perspectives of technical, operational and policy. The results indicate that the hot spots in technical measures are "green energy", "ship optimization" and "waste heat recovery"; the hot spots in operational measures are "speed optimization" and "liner shipping"; and the hot spots in policy measures are "market mechanism" and "international regulations".
    Keywords:  Bibliometric analysis; Emission reduction measures; Green ships; Knowledge graph
    DOI:  https://doi.org/10.1016/j.marpolbul.2025.118166
  67. Vaccines (Basel). 2025 May 12. pii: 509. [Epub ahead of print]13(5):
    Vaccine Research Trends in Africa from 2016 to Mid-2024: A Bibliometric Analysis.
    Chinwe Iwu-Jaja, Duduzile Ndwandwe, Thobile Malinga, Lindi Mathebula, Akhona Mazingisa, Charles Shey Wiysonge.
       BACKGROUND: Vaccine research publications play a crucial role in the scientific process by strategically linking the generation of knowledge with its translation into vaccine policy and practice. This study was designed to understand vaccine and immunization research publication trends in Africa to inform strategic directions for vaccine research and innovation efforts in the continent.
    METHODS: We searched PubMed only for vaccine and immunization-related publications from Africa between 1 January 2016 and 8 August 2024. Metrics such as annual growth rates, geographical distribution, international collaboration, and trend topics were analyzed. We conducted separate analyses for general vaccine research, vaccine clinical trials, and vaccine evidence syntheses (systematic reviews and meta-analyses).
    RESULTS: Vaccine research in Africa demonstrated an annual growth rate of 55.4% (based on the 10,000 records retrieved due to PubMed's export limit), while vaccine trials saw a decline of 6.08% during the study period. The trend topics analysis across vaccine research, trials, and reviews showed that topics shifted from a focus on general vaccine development, immunization, and malaria pre-2020 to COVID-19-related topics in 2020, with post-2020 research returning to traditional topics like immunization schedules, vaccine safety, and pediatric and maternal vaccines. Additionally, the COVID-19 pandemic had a profound impact on vaccine research, leading to a surge in publications for vaccine research, trials, and reviews. About 65.8% of vaccine research featured international co-authorship. Vaccine trials had a higher rate of international co-authorship at 79.8%.
    CONCLUSION: While vaccine research in general in Africa has increased, vaccine trials do not match this increase. The number of clinical trials remained relatively stagnant, reflecting ongoing challenges in the vaccine research ecosystem, particularly in building and sustaining clinical trial capacity across the region. In addition, disparities in research productivity exist between countries. Research prioritization, strategic collaborations, capacity building for research, and improved research infrastructure require critical consideration.
    Keywords:  Africa; immunization; innovation; research; research productivity; vaccine; vaccine reviews; vaccine trials
    DOI:  https://doi.org/10.3390/vaccines13050509
  68. Drug Des Devel Ther. 2025 ;19 4201-4220
    Visual Research of Global Orphan Drug from a Bibliometric Perspective.
    Xiaoya Wen, Guangzhi Jin, Chunxing Wu.
       Objective: This study analyzes the current research landscape and trends in orphan drug development, providing insights for future advancements in the field.
    Methods: Gathering pertinent material from the China National Knowledge Infrastructure (CNKI) and Web of Science databases. Microsoft Office Excel 2017, VOSview 1.6.20, and CiteSpace 6.3R2 were utilised to summarise the present research state and offer insights into research hotspots in the domain of orphan drugs.
    Results: A total of 3598 research papers were included, with Chinese research showing a continuous upward trend, while international research has entered a slow development stage. The field of orphan drug research has formed a sizable research team, and cooperation between international institutions is relatively mature. Meanwhile, the United States and the United Kingdom have strong influence in this research field, while China lacks international cooperation. The research focus in this field mainly involves the development and clinical application of orphan drugs, and domestic and foreign research also has its own emphasis. Maintain consistency in clinical trials and medication support for orphan drugs both domestically and internationally; And foreign research has obvious advantages in the development of orphan drugs. Keyword emergence research indicates that the clinical accessibility and regulatory approval of orphan drugs have become a prominent issue of interest both nationally and globally.
    Conclusion: This study systematically summarises and examines the current research status and emerging trends in the global orphan drug sector by analysing relevant literature from 2000 to 2024 through bibliometric methods. It further delineates the similarities and differences in orphan drug research domestically and internationally, offering valuable references for future investigations in this domain.
    Keywords:  bibliometrics; medication guarantee; orphan drug; orphan drug development; rare disease
    DOI:  https://doi.org/10.2147/DDDT.S506112
  69. Int J Epidemiol. 2025 Apr 12. pii: dyaf058. [Epub ahead of print]54(3):
    How COVID-19 affected academic publishing: a 3-year study of 17 million research papers.
    Matthew Whitaker, Sabrina Rodrigues, Graham Cooke, Bérangère Virlon, Christl A Donnelly, Helen Ward, Paul Elliott, Marc Chadeau-Hyam.
       BACKGROUND: The COVID-19 pandemic induced an unprecedented response from the scientific research community. Previous studies have described disruption of the norms of academic publishing during this time. This study uses an epidemiological statistical toolkit alongside machine-learning methods to investigate the functioning of the scientific information-generation and -consumption ecosystem throughout the pandemic.
    METHODS: A dataset of 17 million scientific research papers that were published between January 2019 and December 2022 was analysed. Data on citations and Altmetrics were harvested, and topic modelling was applied to abstracts. COVID-19-related articles were identified from title text. We investigated publication dynamics, correlations between citation metrics and Altmetrics, rates of publication in preprints, and temporal trends in topics, and compared these metrics in COVID-19 papers vs non-COVID-19 papers.
    RESULTS: Throughout 2020-2, 3.7% of English-language research output was on the topic of COVID-19. Journal articles on COVID-19 were published at a consistent rate during this period, while preprints peaked in early 2020 and decreased thereafter. COVID-19 preprints had lower publication rates in the peer-reviewed literature than other preprints, particularly those that were preprinted during early 2020. COVID-19 research received significantly more media and social media attention than non-COVID-19 research, and preprints received more attention, on average, than journal articles, with attention peaking during the initial wave and subsequent peaks corresponding to the emergence of novel variants. COVID-19 articles exhibited a higher correlation between Altmetrics and citation metrics compared with non-COVID-19 publications, suggesting a strong alignment between scientific and public attention.
    CONCLUSION: This study provides a comprehensive description of the rapid expansion of COVID-19 research, revealing evolving research areas and waxing and waning public interest across different topics. Preprints played an important role in disseminating scientific findings, but the level of coverage of preprinted findings emphasizes the need for guidelines in handling preprint research in media, particularly during a pandemic.
    Keywords:  Altmetrics; COVID-19; bibliometrics; pandemics; policy
    DOI:  https://doi.org/10.1093/ije/dyaf058
  70. Food Res Int. 2025 Aug;pii: S0963-9969(25)00947-0. [Epub ahead of print]213 116609
    Unlocking the potential of fish protein hydrolysates: Bioactive and technofunctional properties, applications, challenges, and future perspectives.
    Geodriane Zatta Cassol, Francisco Lucas Chaves Almeida, Ruann Janser Soares de Castro, Hélia Harumi Sato.
      Global fish consumption and production are steadily increasing, but the processing industry continues to grapple with the dual challenges of reducing costs and minimizing environmental impact while striving to produce healthier food options. In response to these challenges, an increasing number of studies have explored fish protein hydrolysate (FPH). However, a closer look at the existing studies raises new questions, and bibliometric analysis has emerged as a powerful tool to uncover gaps and direct future research. This review aimed to explore the latest trends and main areas of FPH research through a comprehensive bibliometric analysis of original articles published between 2019 and 2024 from the Web of Science (Scientific Citation Index Expanded) database. These findings suggest that the main focus of research has been on improving the functional properties of FPHs, including their potential use as protein ingredients or technological characteristic enhancers, particularly in meat, dairy, and bakery products. By synthesizing current research trends, this review aims to highlight various approaches for developing FPHs with enhanced biological and sensory properties. Such advances will not only improve the hydrolysates themselves, but also the food products they enrich, offering significant benefits to both the food industry and consumers.
    Keywords:  Bibliometrics; Enzyme; Fish by-products; Functional food; Hydrolysis
    DOI:  https://doi.org/10.1016/j.foodres.2025.116609
  71. BMC Bioinformatics. 2025 May 28. 26(1): 140
    Valsci: an open-source, self-hostable literature review utility for automated large-batch scientific claim verification using large language models.
    Brice Edelman, Jeffrey Skolnick.
       BACKGROUND: The exponential growth of scientific publications poses a formidable challenge for researchers seeking to validate emerging hypotheses or synthesize existing evidence. In this paper, we introduce Valsci, an open-source, self-hostable utility that automates large-batch scientific claim verification using any OpenAI-compatible large language model. Valsci unites retrieval-augmented generation with structured bibliometric scoring and chain-of-thought prompting, enabling users to efficiently search, evaluate, and summarize evidence from the Semantic Scholar database and other academic sources. Unlike conventional standalone LLMs, which often suffer from hallucinations and unreliable citations, Valsci grounds its analyses in verifiable published findings. A guided prompt-flow approach is employed to generate query expansions, retrieve relevant excerpts, and synthesize coherent, evidence-based reports.
    RESULTS: Preliminary evaluations across claims from the SciFact benchmark dataset reveal that Valsci significantly outperforms base GPT-4o outputs in citation hallucination rate while maintaining a low misclassification rate. The system is highly scalable, processing hundreds of claims per hour through asynchronous parallelization.
    CONCLUSIONS: By providing an open and transparent platform for large-batch literature verification, Valsci substantially lowers the barrier to comprehensive evidence-based reviews and fosters a more reproducible research ecosystem.
    Keywords:  Batch processing; Bibliometric scoring; Bioinformatics; Chain-of-Thought; Claim verification; Large language models; Open-source; Retrieval-augmented generation
    DOI:  https://doi.org/10.1186/s12859-025-06159-4
  72. J Asthma Allergy. 2025 ;18 779-793
    Application of Biologics in the Treatment of Asthma in the Past Two Decades: A Bibliometric Analysis and Beyond.
    Zicong Zhou, Xiaoying Chen, Shixiu Liang, Jing Li, Nanshan Zhong, Ruchong Chen.
      This study aims to demonstrate the bibliometric characteristics of articles on biologics for asthma treatment over the past two decades. There were 3395 articles published in 653 journals from 91 countries/regions from January 1, 2000 to September 30, 2023. The results showed biologics changes the course of asthma has attracted the interest of researchers and asthma remission has recently been proposed by researchers. Therefore, the goal of T2-high asthma management was shifted from controlling to complete remission. There was also growing interest among researchers in alleviating symptoms in T2-low asthma. New biological targets also need to be discovered when patients do not achieve satisfactory therapeutic outcomes with biologic agent, and one of the potential future direction for a treatment breakthrough lies in the combination of two biologics or the utilization of novel biologics that target dual sites. The development of biologics has progressed rapidly and has demonstrated their effectiveness in clinic, however, biologics still face multifaceted challenges and require further research to identify additional targets or enhance efficacy.
    Keywords:  T2 inflammation; asthma; bibliometric analysis; biologics
    DOI:  https://doi.org/10.2147/JAA.S514250
  73. Sensors (Basel). 2025 May 12. pii: 3041. [Epub ahead of print]25(10):
    Sustainability Awareness in Manufacturing: A Review of IoT Audio Sensor Applications in the Industry 5.0 Era.
    Stefania Ferrisi.
      The integration of Internet of Things audio sensors with Artificial Intelligence techniques is revolutionizing predictive maintenance systems in machining operations, playing a pivotal role in advancing the sustainability goals of Industry 5.0. The synergy between these technologies enhances operational efficiency, reduces downtime, and minimizes waste, aligning with energy conservation and resource optimization goals. The use of audio sensors provides a cost-effective, non-intrusive solution for machining operations. In this work, a bibliometric analysis of the progress achieved in this field is performed, identifying which challenges have been extensively addressed and which remain unexplored. By assessing the existing research, this study aims to highlight gaps that necessitate further investigation, guiding future research efforts toward the most critical and promising directions for enhancing predictive maintenance in machining processes. Through a comprehensive analysis of publication trends, collaboration networks, and research gaps, this study intends to provide valuable insights for academia and industry stakeholders, to motivate their efforts in this field. Understanding these trends is essential for fostering innovation and ensuring that the development of predictive models continues to evolve to maximize both production efficiency and sustainability.
    Keywords:  acoustic emissions; audio signals; bibliometric analysis; machining; predictive maintenance
    DOI:  https://doi.org/10.3390/s25103041
  74. Res Integr Peer Rev. 2025 May 27. 10(1): 8
    False authorship: an explorative case study around an AI-generated article published under my name.
    Diomidis Spinellis.
       BACKGROUND: The proliferation of generative artificial intelligence (AI) has facilitated the creation and publication of fraudulent scientific articles, often in predatory journals. This study investigates the extent of AI-generated content in the Global International Journal of Innovative Research (GIJIR), where a fabricated article was falsely attributed to me.
    METHODS: The entire GIJIR website was crawled to collect article PDFs and metadata. Automated scripts were used to extract the number of probable in-text citations, DOIs, affiliations, and contact emails. A heuristic based on the number of in-text citations was employed to identify the probability of AI-generated content. A subset of articles was manually reviewed for AI indicators such as formulaic writing and missing empirical data. Turnitin's AI detection tool was used as an additional indicator. The extracted data were compiled into a structured dataset, which was analyzed to examine human-authored and AI-generated articles.
    RESULTS: Of the 53 examined articles with the fewest in-text citations, at least 48 appeared to be AI-generated, while five showed signs of human involvement. Turnitin's AI detection scores confirmed high probabilities of AI-generated content in most cases, with scores reaching 100% for multiple papers. The analysis also revealed fraudulent authorship attribution, with AI-generated articles falsely assigned to researchers from prestigious institutions. The journal appears to use AI-generated content both to inflate its standing through misattributed papers and to attract authors aiming to inflate their publication record.
    CONCLUSIONS: The findings highlight the risks posed by AI-generated and misattributed research articles, which threaten the credibility of academic publishing. Ways to mitigate these issues include strengthening identity verification mechanisms for DOIs and ORCIDs, enhancing AI detection methods, and reforming research assessment practices. Without effective countermeasures, the unchecked growth of AI-generated content in scientific literature could severely undermine trust in scholarly communication.
    Keywords:  Academic fraud; Author misattribution; Fake article; Generative AI; Predatory journal; Scientific integrity
    DOI:  https://doi.org/10.1186/s41073-025-00165-z
  75. J Aging Stud. 2025 Jun;pii: S0890-4065(25)00026-X. [Epub ahead of print]73 101332
    Exploring the meaning of home for the older adults: A bibliometric analysis of environmental and psychological needs (1969-2023).
    Milad Olfat.
      As the older adult population continues to grow and modern lifestyles evolve, many older adults encounter challenges in adapting to contemporary homes or transitioning to new living environments. Factors such as loneliness, diminished physical capabilities, and relocation to institutional care settings further exacerbate these difficulties. Designing supportive environments that cater to the psychological needs of older adults can enhance their sense of place attachment, comfort, and overall well-being. This paper aims to present a comprehensive bibliometric review of the existing body of research on the meaning of home, addressing knowledge gaps related to the psychological needs of older adults. The study is based on the analysis of 678 English-language articles indexed in the Scopus database, published between 1969 and 2023. Data were analyzed using VOS Viewer 1.6.20 software, and the PRISMA checklist was employed to ensure accuracy in bibliometric reporting. The findings indicate that research on this topic has predominantly developed around five main domains: "Transactional Processes with the Environment and Factors Affecting Health and Well-being," "Resilience and Vulnerability in Living Environments," "Older Adults Care and Welfare Services," "Architectural Design Principles for Care Environments and Aging Equipment," and "Independent Living and Modern Technologies." Nevertheless, expanding the scope to include non-English studies from diverse geographical contexts is expected to contribute to a more comprehensive framework for defining the meaning of home for older adult individuals across different cultures.
    Keywords:  Bibliometric analysis; Design; Environmental needs; Meaning of home; Older adults
    DOI:  https://doi.org/10.1016/j.jaging.2025.101332
  76. Nature. 2025 May 28.
    The 'pivot penalty': scientists get cited less after switching fields, analysis finds.
    Mariana Lenharo.
      
    Keywords:  Publishing; Research management; Scientific community
    DOI:  https://doi.org/10.1038/d41586-025-01664-1
  77. Front Nutr. 2025 ;12 1575130
    The dynamic linkage between covid-19 and nutrition: a review from a probiotics perspective using machine learning and bibliometric analysis.
    Christos Stefanis, Christina Tsigalou, Ioanna Bezirtzoglou, Gregoria Mitropoulou, Chrysoula Voidarou, Elisavet Stavropoulou.
       Introduction: The pandemic crisis is now a memorable milestone in the history of science, not only for the impacts on the population's health but also for the effort of the medical community to find immediate solutions amid the pandemic so that appropriate therapeutic means can be provided. Diet and nutrition could not fail to be studied in the context of combating the side effects of COVID-19. This study attempts to detect the relationship between dietary patterns and the disease of COVID-19 and emphasizes research on probiotics by mapping the knowledge produced during the pandemic until 2024.
    Methods: In addition to bibliometrics, a machine-learning framework, ASReview, was used to structure the literature search. With this method, 2,309 articles were collected from the PubMed database, with 599 constituting inputs into bibliometric software and further analysis.
    Results: Food choices, dietary patterns, vitamins and their role (vitamin D), obesity, and probiotics were keywords that attracted global research attention. Dietary supplements also constituted a field of study regarding the evolution of the disease and the impact they could have after the first pandemic wave.
    Discussion: Probiotics were considered an adjunct therapeutic intervention not only during the period before the development of vaccines but also alongside other therapeutic solutions. Whether used preventively or during the treatment phase, probiotics were studied to combat COVID-19 due to their potential role in immunomodulation and ability to regulate gut microbiota during respiratory infections.
    Keywords:  ASReview; COVID-19; SARS-CoV-2; bibliometrics; diet; nutrition; probiotics
    DOI:  https://doi.org/10.3389/fnut.2025.1575130
  78. Indian J Crit Care Med. 2025 May;29(5): 401
    Message from the New Editor-in-Chief: Continuity and Change, Impact and Visibility.
    Jigeeshu V Divatia.
      
    Keywords:  Critical care; India; Journal impact factor; Research; Social media
    DOI:  https://doi.org/10.5005/jp-journals-10071-24976
  79. Iran J Med Sci. 2025 May;50(5): 278-303
    Uncovering Novel Anti-Lung Cancer Compounds: Insights from Marine Sponge-Derived Agents: A Bibliometric Review.
    Afshin Zare, Alireza Afshar, Nadiar M Mussin, Asset A Kaliyev, Raisa A Aringazina, Nader Tanideh, Mahdi Mahdipour, Farhad Rahmanifar, Zhanna Zhussupova, Beibyt Tlektesuly Baizakov, Amin Tamadon.
       Background: Lung cancer remains a leading cause of cancer-related mortality, necessitating improved treatment strategies. This study collectively highlights the valuable potential of marine sponges as a source for discovering new anti-tumor agents.
    Methods: We conducted a bibliometric analysis to identify anticancer compounds from marine sponges using PubMed (2018-2023). The search included keywords such as "marine sponge," "cancer," "neoplasm," "proliferation," "cytotoxicity," "tumor," "sesquiterpene," "alkaloid," and "quinones." Inclusion criteria focused on studies related to lung cancer and marine sponge-derived compounds, excluding non-cytotoxic activities and unrelated species. Data were extracted in comma-separated values (CSV) format and analyzed via VOSviewer. Molecular docking identified compounds with strong binding to apoptotic receptors in lung cancer cells. PROTOX and Way2Drug tools predicted the pharmacological properties of selected compounds as potential drugs.
    Results: The bibliometric analysis identified alkaloids, sesquiterpenes, and quinones as key keywords. Dactyloquinone B-D, dysidavarone D, smenohamien F, and sollasin E demonstrated strong binding to apoptotic receptors in lung cancer cells, suggesting potential as anti-lung cancer drugs. Pharmacological analyses revealed promising effects and potential side effects, highlighting their suitability for further drug development. These findings provide a foundation for novel targeted therapies for lung cancer.
    Conclusion: This study highlights the potential of alkaloids and sesquiterpenes derived from marine sponges as promising anti-lung cancer agents, emphasizing the need for further in vitro, in vivo, and clinical investigations to validate their therapeutic efficacy.
    Keywords:   Antineoplastic agents; Apoptosis; Bibliometrics; Lung neoplasms; Porifera
    DOI:  https://doi.org/10.30476/ijms.2024.103270.3646
  80. PLoS One. 2025 ;20(5): e0318875
    Negotiating science funding: The interplay of merit, bias, and administrative discretion in grant allocation in Kazakhstan.
    Darkhan Medeuov, Kamilla Rodionova, Zhaxylyk Sabitov, Adil Rodionov.
      This paper analyzes 4,488 applications from a grant funding competition held in 2017 in Kazakhstan. The competition had a two-stage design: first, anonymous subject matter experts evaluated the applications' scientific potential; then, open panels of local science managers made the final decisions. We analyze a range of bibliometric, institutional, and demographic variables associated with the applications and show that review scores account for only a small variation in success rates. The most important factor is the organizational closeness to decision-making. Gender also plays a role: we find that, net of academic merit, men and women investigators receive similar review scores, yet the panelists grant awards to men more often than to women. We further demonstrate that the gender gap emerges due to decisions made in a specific domain-Natural Resource Management.
    DOI:  https://doi.org/10.1371/journal.pone.0318875
  81. Arch Cardiol Mex. 2025 ;95(2): 239-242
    The challenges of indexing and impact factor in Latin American cardiology journals.
    Daniel L Piskorz.
      Bibliographic search is an essential tool to find answers to medical questions, stimulate the development of research projects and properly focus their design. The organization of bibliographic databases of primary sources of information is an essential need for the advancement of knowledge. On the Internet it is possible to access free of charge databases created and maintained, for the most part, by research centers, universities and public organizations. Most Latin American journals are considered in regional bibliographic databases, favoring the regional exposure of research products. However, the great challenge is indexing in Medline, mainly due to its global impact. The quality, scientific relevance and innovation of the articles published in a journal marks its impact factor. The editorial body of the journals tries to build and offer a high-quality scientific product, giving prestige to the scientific society it represents.
    Keywords:  Editores; Editors; Factor de impacto; Impact factor; Indexación; Indexing; Latin American journals; Revistas latinoamericanas
    DOI:  https://doi.org/10.24875/ACM.24000216
  82. J Funct Biomater. 2025 May 18. pii: 184. [Epub ahead of print]16(5):
    A Comprehensive Literature Review for Total Hip Arthroplasty (THA): Part 2-Material Selection Criteria and Methods.
    Salvatore Garofalo, Chiara Morano, Luigi Bruno, Leonardo Pagnotta.
      Total Hip Arthroplasty (THA) is a widely used surgical procedure to restore mobility and reduce pain in patients with hip joint disorders. Implant success and longevity are influenced by the selection of appropriate materials. This study presents a comprehensive literature review based on structured searches in Scopus and Web of Science, focusing on material selection criteria and methods in THA. The inclusion criteria targeted original studies and reviews addressing material properties, selection techniques, and clinical performance. A bibliometric analysis and keyword co-occurrence network were used to highlight major research themes. The review examines traditional materials such as Metal-on-Polyethylene (MoP), as well as advanced options like ceramics, composites, and Functionally Graded Materials (FGMs). Key challenges discussed include aseptic loosening, wear resistance, and stress shielding. Selection methodologies such as Multi-Criteria Decision-Making (MCDM), Weighted Properties Methods (WPM), and computational tools like Ashby charts and CES Selector are analyzed. The findings from international arthroplasty registries show that more than half of implant failures are linked to material-related factors. This study therefore aims to guide material selection processes in THA by aligning clinical performance with biomechanical and biological requirements, supporting improved implant outcomes and long-term surgical success. Future developments should focus on patient-specific solutions and continuous innovation.
    Keywords:  bearing surfaces; material selection; selection methods; total hip arthroplasty (THA); total hip replacement (THR)
    DOI:  https://doi.org/10.3390/jfb16050184
  83. Front Psychol. 2025 ;16 1588644
    Bibliometric analyses of factors influencing color preferences in urban environmental spaces.
    Chunshuo Qu, Jianfei Dong, Weijia Wang.
      Urban color is a crucial visual component of urban aesthetics, directly reflecting national traditional aesthetic consciousness and historical culture, and holding significant aesthetic value and research relevance. As a key factor in urban color studies, color preference significantly impacts human behavior and plays a vital role in urban planning and development. However, a comprehensive and systematic understanding of urban color preferences remains underexplored. This study examines 379 relevant studies using bibliometric review methods and literature visualization tools, classifying, and synthesizing them according to research hotspots and fields. Four primary categories influencing urban color preference were identified: personal attributes, socio-cultural influences, environmental space, and dynamic factors. The analysis also highlights the psychological mechanisms underlying color preference, including its effects on emotional regulation, cognitive processing, and social identity. The findings contribute to the field by offering a data-driven framework for understanding urban color preferences and proposing practical applications for urban planning. The study emphasizes the importance of color preference in promoting human well-being and sustainable urban development, with implications for future interdisciplinary research.
    Keywords:  bibliometric analyses; color preference; color psychology; environmental psychology; urban space environment
    DOI:  https://doi.org/10.3389/fpsyg.2025.1588644
  84. Nature. 2025 May 28.
    The pivot penalty in research.
    Ryan Hill, Yian Yin, Carolyn Stein, Xizhao Wang, Dashun Wang, Benjamin F Jones.
      Scientists and inventors set the direction of their work amid evolving questions, opportunities and challenges, yet the understanding of pivots between research areas and their outcomes remains limited1-5. Theories of creative search highlight the potential benefits of exploration but also emphasize difficulties in moving beyond one's expertise6-14. Here we introduce a measurement framework to quantify how far researchers move from their existing work, and apply it to millions of papers and patents. We find a pervasive 'pivot penalty', in which the impact of new research steeply declines the further a researcher moves from their previous work. The pivot penalty applies nearly universally across science and patenting, and has been growing in magnitude over the past five decades. Larger pivots further exhibit weak engagement with established mixtures of prior knowledge, lower publication success rates and less market impact. Unexpected shocks to the research landscape, which may push researchers away from existing areas or pull them into new ones, further demonstrate substantial pivot penalties, including in the context of the COVID-19 pandemic. The pivot penalty generalizes across fields, career stage, productivity, collaboration and funding contexts, highlighting both the breadth and depth of the adaptive challenge. Overall, the findings point to large and increasing challenges in effectively adapting to new opportunities and threats, with implications for individual researchers, research organizations, science policy and the capacity of science and society as a whole to confront emergent demands.
    DOI:  https://doi.org/10.1038/s41586-025-09048-1
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