bims-evares Biomed News
on Evaluation of research
Issue of 2025–09–28
76 papers selected by
Thomas Krichel, Open Library Society



  1. Meat Sci. 2025 Sep 11. pii: S0309-1740(25)00213-X. [Epub ahead of print]231 109952
      The Meat Science journal is a high-impact, internationally recognized scientific and prestigious journal that has served as a leading platform for publishing groundbreaking research in meat science for over four decades. Given its prominent role in shaping the field, investigating the journal's publication trends and scientific influence provides valuable insight into the evolution of meat science research. In this respect, we conducted a detailed bibliometric analysis of publications in the Meat Science journal from 1980 to 2025. The analysis aimed to map the journal's intellectual structure, research dynamics, and scholarly impact, establishing its position as a leading journal in the field of meat science with 8414 publications. A comprehensive dataset was extracted from the Web of Science Core Collection, including publication type, year, author affiliation, country, citation counts, and keyword information. Analytical procedures were conducted using VOSviewer (v1.6.19) and the Bibliometrix package with the Biblioshiny interface in R (v4.4.0). These procedures enabled robust visualization and mapping of co-authorship networks, the co-occurrence of keywords, author citation relationships, and bibliographic coupling. Citation-based metrics and trend analyses were further supported by the "Analyze Results" and "Citation Reports" functions in Web of Science. The analysis revealed publication trends over time, leading contributors and institutions, geographical patterns, and thematic shifts over four decades. The results showed that research articles, proceedings, and review articles were more dominant than other article types. The United States (1283 publications; 56,041 citations) and Spain (1264 publications; 65,089 citations) were the most influential contributors, while INRAE (France) emerged as the leading institution (268 publications; 17,916 citations). Thematic mapping revealed a transition from traditional focuses (e.g., meat quality, tenderness, lipid oxidation) toward emerging domains such as sustainability-encompassing animal welfare, environmental footprint reduction, meat preservation, innovative packaging materials, food safety, and waste minimization-alongside consumer perception and the development of functional meat products. This work highlights the evolving role of the journal in advancing meat science and offers strategic insights for researchers, institutions, and policymakers in the field.
    Keywords:  Bibliometric analysis; Citation analysis; Meat science journal; Research impact; Scientific publishing trends
    DOI:  https://doi.org/10.1016/j.meatsci.2025.109952
  2. Medicine (Baltimore). 2025 Sep 19. 104(38): e44421
       BACKGROUND: This study aimed to provide a thorough overview of research hotspots in mitophagy in osteoarthritis through a bibliometric analysis approach.
    METHODS: A comprehensive literature search was conducted on the Web of Science Core Collection on September 9, 2024. Key metrics were calculated using Microsoft Excel 2019, and bibliometric analysis and visualization were performed with VOSviewer 1.6.20, CiteSpace 6.3.R1, and R 4.3.3.
    RESULTS: The analysis covered 259 articles published between 2008 and 2024, involving 1679 authors from 924 institutions across 41 countries, indicating growing interest in mitophagy research related to osteoarthritis. Wenzhou Medical University emerged as the most prolific institution with 25 articles. The journal Osteoarthritis and Cartilage was a leading venue, showing high citation metrics and an impact factor of 7.2. The most cited article was "Pesticides and human chronic diseases: Evidence, mechanisms, and perspectives" from Toxicology and Applied Pharmacology. The keyword "apoptosis" was the most frequently used, along with significant terms like "oxidative stress" and "mitochondrial dysfunction." Keyword burst analysis indicated intensified focus on "mammalian target of rapamycin" and "cell death."
    CONCLUSION: This bibliometric analysis highlights a growing interest in mitophagy in osteoarthritis research, emphasizing its potential as a therapeutic target and signaling future advancements in this field.
    Keywords:  bibliometrics analysis; mitophagy; osteoarthritis
    DOI:  https://doi.org/10.1097/MD.0000000000044421
  3. Acta Orthop Traumatol Turc. 2025 Sep 12. 59(5): 315-321
      Objective: This study aimed to assess the contributions and global impact of Turkish orthopedics and traumatology research published in high-impact international journals over the past decade (2014-2023). By examining article types, citation metrics, journal impact factors, and author a!liations, the aim was to highlight publication trends, strengths, and areas needing improvement within Turkish orthopedic research. Methods: Using the Web of Science database, keywords were searched under journal categories including "Orthopedics," "Orthopedics, Rehabilitation and Sports Medicine," and "Sports Sciences." Articles from the top 40 orthopedic journals indexed in Science Citation Index Expanded were identified and selected based on their 2022 impact factors. Articles published between January 2014 and December 2023 with first authors a!liated with a Turkish institution were included. Citation density was calculated by dividing the total number of citations by the number of years since publication. Data extracted included publication type, citation count, citation density, research methodology, author a!liations, and institutional contributions. Results: Out of 70 279 articles published globally, 425 orthopedic articles with Turkish first authorship were identified in the selected journals. Most articles were clinical (88.7%), with the most frequent article types being case presentations (31.3%), retrospective cohort studies (17.9%), and laboratory research (11.3%). The least common types were expert opinions, epidemiological studies, and meta-analyses. The majority of articles appeared in Spine Journal (34.6%) and Knee Surgery, Sports Traumatology, Arthroscopy (27.3%), with no articles published in the highest-ranked journal (British Journal of Sports Medicine). Spine surgery was the leading subfield (29.9%), followed by sports, shoulder, and elbow surgery (22.6%) and reconstructive surgery (16%). Orthopedic specialists comprised 56% of first authors, with multicenter studies representing 65.4% of the articles. Public institutions accounted for 80.1% of published articles, while private institutions contributed 19.9%. A total of 356 articles were cited 8349 times, with a median citation number of 9 per article. Mean citation density was highest in meta-analysis (8.5 citation/year), epidemiological studies (8.3 citation/year), and randomized controlled trials (7.8 citation/ year), while lowest in case presentations (0.3 citation/year), expert opinions (0.4 citation/year), and laboratory research (2.2 citation/year). Conclusion: Turkish orthopedic research has maintained a significant presence in top orthopedic journals, mostly through clinical studies, especially in spinal and sports injury subfields. Despite high publication volume, citation impact remains relatively lower. Future e"orts should encourage higher-impact study designs, international collaborations, and standardized research evaluations to enhance the global influence of Turkish orthopedic literature. Level of Evidence: N/A.
    DOI:  https://doi.org/10.5152/j.aott.2025.25362
  4. Front Sports Act Living. 2025 ;7 1609141
       Background: Running shoes can protect the feet, enhance performance and lower the injury risk during running. While extensive research has been investigated on footwear design and innovation in running, the scientific guideline underlying running shoe research remain inadequately explored and established.
    Purpose: The aims of this study was to conduct a bibliometric analysis of publications in running shoes for identifying research hotspots and future trends. The results from this study can provide valuable references for future studies and contribute to the scientific advancement of running shoe design.
    Method: Articles on running shoes were collected and screened from the Web of Science Core Collection database covering the years 2005-2024. After duplicate and irrelevant articles removed, CiteSpace, VOSviewer, and R-biblioshiny were used to perform visualized analyses of authors, titles, journals, countries, institutions, keywords, research directions, and cited references. Co-citation maps were created to provide a clear representation of research hotspots and knowledge structures.
    Result: A total of 1,576 articles on running shoes were identified across 394 journals spanned 69 countries and 3,599 institutions, with peak publication volume found in 2022. The United States generated the highest number of publications, followed by China and the United Kingdom. The University of Calgary produced the highest publication output. Gu YD was the top author to produce the most publications, while Lieberman DE was identified as the most influential scholar in the field. The Medicine & Science in Sports & Exercise have been the most prominent journals in this field. Trend keywords had centered on running injuries (e.g., "barefoot," "ground reaction force," and "injuries") and performance (e.g., "running economy," "performance," and "metabolic cost"), which have been clustered into eight distinct labels.
    Conclusion: This is the first study to present bibliometric analysis on running shoes literature over the past 20 years, highlighting the key hotspots and future trends. Overall, the annual publications on running shoes has steadily increased. Current research have focused on the biomechanics and physiological indicators of runners whilst wearing running shoes to explore the associated injury risks and running performance, with particular emphasis on the impact of minimalist shoes.
    Keywords:  bibliometrics; running injuries; running performance; running shoe; visualization mapping
    DOI:  https://doi.org/10.3389/fspor.2025.1609141
  5. J Multidiscip Healthc. 2025 ;18 5977-6001
       Purpose: Numerous studies have suggested that exosomes are associated with rheumatic diseases, but no bibliometric analysis has been performed. This study presents the first comprehensive bibliometric analysis aiming to evaluate the current research hotspots and to anticipate future trends.
    Methods: An electronic search was conducted in the Web of Science Core Collection (WOSCC) using exosome and rheumatic disease-specific terminology to identify eligible studies published from January 1, 2000 to October 19, 2024. Only English-language articles and review articles were selected for bibliometric analysis. Data analysis and visualization were conducted using CiteSpace 6.2.R3, VOSviewer 1.6.18, and the Bibliometrix R package.
    Results: A total of 1,251 publications with 49,374 citations were extracted from the WOSCC database. Both publication and citation frequency increased steadily. 255 different countries or regions, 4,413 institutions and 7,213 authors contributed to the field. China and the USA are the leading countries and Shanghai Jiao Tong University has a significant influence. Théry C is the most frequently co-cited researcher. Most papers are published in Frontiers in Immunology, while Stem Cell Research & Therapy has the highest citations. Research is primarily concentrated in cell biology, immunology, and experimental medicine. Exosm, mesenchymal stem cells (MSCs), autoimmunity, regeneration, and others are major areas of research in this field. Research hotspots primarily focus on the diagnostic potential and therapeutic applications of exosomes in osteoarthritis and rheumatoid arthritis. Exosomes derived from MSCs and their cargo, such as microRNAs (miRNAs), have the potential to serve as biomarkers and therapeutic vehicles in these diseases.
    Conclusion: This study firstly quantifies and identifies the current status and research frontiers of exosomes in RDs by using bibliometric analysis, which may provide valuable insights for researchers to navigate trends and emerging applications into the field.
    Keywords:  bibliometric; exosomes; mesenchymal stem cells; osteoarthritis; rheumatoid arthritis
    DOI:  https://doi.org/10.2147/JMDH.S536183
  6. J Robot Surg. 2025 Sep 24. 19(1): 630
      This study conducts a bibliometric analysis of the literature related to robotic surgery in spinal surgery to identify research hotspots and provide a foundation and suggestions for its future development. The paper focuses on the fields of robotics and spinal surgery, retrieving relevant literature from the Web of Science Core Collection (WOSCC) database from 2001 to December 31, 2024. The number of publications per year is quantified using GraphPad Prism, and CiteSpace is employed to analyze the collaboration among authors, countries, and institutions, as well as the co-citation patterns of journals or literature. Finally, keyword clustering and visualization analysis were performed. China and the USA lead in the number of publications and demonstrate the closest collaboration with other countries and institutions. The main identified keywords include "accuracy" and "spine surgery" with research hotspots focusing on "image guidance" and "biomechanics" The research on robotic surgery in spinal surgery shows a continuous growth trend, indicating that this field will remain a focal point in spinal surgery research in the future.
    Keywords:  Bibliometrics; Robot; Spine; Surgery; Visual analysis
    DOI:  https://doi.org/10.1007/s11701-025-02825-0
  7. J Oral Maxillofac Surg. 2025 Sep 05. pii: S0278-2391(25)00740-2. [Epub ahead of print]
       BACKGROUND: Orbital fractures are common midfacial injuries that present complex challenges due to the anatomical and functional intricacies of the orbit. Understanding the evolution of surgical approaches and academic perspectives is essential to guide future research and multidisciplinary management.
    PURPOSE: The purpose of this study was to describe the evolution of management of orbital fractures, highlighting scholarly focus to inform future research and multidisciplinary care.
    STUDY DESIGN, SETTING, SAMPLE: This bibliometric study was conducted in January 2025. An electronic literature search was conducted on Web of Science Core Collection with search keys of orbital fracture and associated terms. Articles published between 1950 and 2024 were eligible for screening. Inclusion criteria were full-length, English-language articles, and ranking among the top 100 most-cited articles in the search results. Any literature not in English, editorial materials, letters, book chapters, meeting abstracts, notes, and reprints were excluded. The identified literature was analyzed using bibliometric and sentiment analysis.
    OUTCOME VARIABLES: Information on the title, abstract, authors, year of publication, country of origin, primary institution, keywords, citation count, and number of references was retrieved from all identified articles. For the top 100 most cited articles, additional data were collected, including journal, corresponding author's specialty, and research topics.
    ANALYSES: Sentiment analysis was performed on the top 100 most-cited articles using a natural language processing model to classify abstracts as positive, neutral, or negative, reflecting the overall tone of orbital fracture research. Bibliometric analyses and graphical presentations were generated using VOSviewer (Leiden University, The Netherlands).
    RESULTS: A total of 981 articles were identified, representing 66 countries. The United States was the top publishing country with a total of 326 (33.2%) articles, followed by South Korea and China. The top 5 institutions were Shanghai Jiaotong University, Harvard University, University of Maryland, Johns Hopkins University, and Helsinki University Hospital. Articles from Baylor College of Medicine were the most cited, with a total of 460 citations. For the 100 most-cited articles, the United States remained the leading country; however, our overlay map demonstrated a subtle shift toward other countries in recent years. Four clusters of keywords were identified, including "Epidemiology," "Management," "Complications," and "Fracture Types," suggesting research trends from diagnosis and management to materials and surgical planning. These articles most frequently appeared in the Plastic and Reconstructive Surgery (n = 9, 9%), the International Journal of Oral & Maxillofacial Surgery (n = 7, 7%), and the Journal of Craniofacial Surgery (n = 7, 7%), among a total of 46 journals. Corresponding author's specialty revealed that most were in the field of ophthalmology (n = 36, 36%), followed closely by oral and maxillofacial surgery (n = 24, 24%), and then otolaryngology-head and neck surgery (n = 15, 15%).
    CONCLUSIONS AND RELEVANCE: This bibliometric analysis reveals a growing interest in orbital fracture research, with increasing publications and citations over time. The research focus has evolved from diagnosis and management to surgical innovation, with a predominance of positive sentiment in highly cited literature. These findings offer valuable insights to inform future interdisciplinary collaboration and research focus.
    DOI:  https://doi.org/10.1016/j.joms.2025.08.016
  8. Insects. 2025 Sep 09. pii: 945. [Epub ahead of print]16(9):
      Dragonflies and damselflies (Odonata) play important roles in ecology and are used as model organisms in evolutionary studies, but a comprehensive overview of Odonata research has been lacking. Here, we conducted a bibliometric analysis of Odonata literature from 1974 to 2023 using Web of Science (Science Citation Index Expanded) data and CiteSpace software. We analyzed over 5000 publications to identify major contributors, research hotspots, and emerging trends in this field. The results show that annual research output increased greatly over time, with the United States being the most prolific country. Co-citation and keyword analyses revealed several dominant research themes, including life history and evolution, flight mechanics and predatory behavior, habitat and community ecology, biodiversity and conservation under environmental change, molecular phylogenetics, reproductive biology, and dragonfly wing mechanics. Citation burst analysis highlighted emerging fronts such as global Odonata species diversity and conservation efforts, advanced molecular phylogenetic studies, the use of dragonflies and damselflies as model species and bioindicators, and new investigations into wing kinematics. In conclusion, this study provides a quantitative retrospective of five decades of Odonata research, offering insights into the field's development and guiding future research directions.
    Keywords:  Odonata; bibliometric analysis; biodiversity; conservation; damselfly; dragonfly; research trends
    DOI:  https://doi.org/10.3390/insects16090945
  9. Discov Oncol. 2025 Sep 26. 16(1): 1737
       BACKGROUND: Mismatch repair deficiency (dMMR) is observed in 12-15% of sporadic colon carcinomas. dMMR tumors have unique genetic characteristics, with mutation rates 10 to 100 times higher than those of tumors with intact mismatch repair functions. Approximately 15% of colon cancer cases exhibit mismatch repair deficiency. Moreover, the status of DNA mismatch repair deficiency holds prognostic and predictive significance in both non-metastatic and metastatic colon cancer. Therefore, we aim to comprehensively conduct a bibliometric analysis of research on mismatch repair-deficient colon cancer studies to identify research trends and potential future directions.
    METHODS: A total of 1428 relevant articles from January 1, 1995 to July 1, 2024 were obtained from the Web of Science Core Collection. Knowledge graphs were analyzed and visualized using VOSviewer, CiteSpace, and Scimago Graphica software as bibliometric tools to extract or calculate evaluation metrics. Publications were categorized by country, institution, author, journal, highly cited article, and keyword. These variables were compared in terms of publication and academic impact, including citation count, citation impact, H-index, and journal impact factor.
    RESULTS: A total of 1428 publications related to mismatch repair-deficient colon cancer were retrieved from 351 countries and 6953 research institutions. The United States and China led the way in terms of the number of publications and impact; the most prolific institution was Sun Yat-sen University, followed by the Mayo Clinic; Cancers was the journal with the most publications, while Cancer Research was the most cited journal; André, Thierry was the most prolific author, and Thibodeau, Stephen N. had the highest H-index of all authors; the five most cutting-edge keywords identified were colorectal cancer, microsatellite instability, immunotherapy, Lynch syndrome, and mismatch repair. Among these, topics such as Nivolumab, PD-1 blockade, open label, mismatch repair deficient, immune checkpoint inhibitors, and metastatic colorectal cancer remain the hot topics in this field.
    CONCLUSION: Research on mismatch repair-deficient colon cancer is poised to enter a golden age in the coming years. This study not only provides insights into the directions and frontiers of mismatch repair-deficient colon cancer research but also highlights that the treatment of mismatch repair-deficient colon cancer benefits from a multidisciplinary approach. The comparison of different immune-assisted therapies will contribute to a more comprehensive understanding of the therapeutic landscape. Ultimately, large-scale and well-designed clinical trials are required to establish a recognized standard that can benefit more patients with mismatch repair-deficient colon cancer.
    Keywords:  Bibliometrics; CiteSpace; Immunization; Mismatch repair-deficient colon cancer; VOSviewer
    DOI:  https://doi.org/10.1007/s12672-025-03396-0
  10. J Craniofac Surg. 2025 Sep 22.
       INTRODUCTION: This study employs bibliometric methods to identify research hotspots and developmental trends in lip scar research, offering insights for future studies.
    MATERIALS AND METHODS: A dataset of lip scar publications (2005-2024) was extracted from the Web of Science Core Collection (SCI-EXPANDED). Using VOSviewer 1.6.20 and CiteSpace 6.3.3, we conducted analyses of annual output, collaborative networks (countries/institutions/authors), co-citation, keyword clustering, and burst detection, supported by visual knowledge maps.
    RESULTS: The 784 retrieved articles (2005-2024) reflected a steady upward trend in annual publications. Contributions spanned 69 countries, led by the USA (28.70%), China (21.81%), and Japan (6.50%). Top institutions included Shanghai Jiao Tong University (31 publications, 3.95%), Peking Union Medical College & Chinese Academy of Medical Sciences (25 publications, 3.19%), and Chang Gung Memorial Hospital (21 publications, 2.68%). Professor Qingfeng Li (Shanghai Jiao Tong University) and the Journal of Craniofacial Surgery ranked highest in author and journal outputs, respectively. Keyword analysis identified cleft lip/palate, lip reconstruction, wound healing, squamous cell carcinoma, parental perception, eye-tracking, contracture, CO2 laser, and color matching as critical research themes.
    CONCLUSIONS: This bibliometric analysis maps global research productivity, collaborative frameworks, and emerging hotspots in lip scar studies. It highlights dominant journals and key contributors while forecasting future research directions encompassing etiology, treatment innovations, and prognostic evaluation. These findings offer a strategic foundation for advancing lip scar research.
    Keywords:  Bibliometrics; cleft lip; lip scars; visualization analysis; wound healing
    DOI:  https://doi.org/10.1097/SCS.0000000000011997
  11. Cureus. 2025 Aug;17(8): e90708
      This bibliometric review analyzed global research trends on the relationship between obstructive sleep apnea hypopnea syndrome (OSAHS) and metabolic dysfunction-associated steatotic liver disease (MASLD) from 2010 to 2024. A total of 115 PubMed-indexed publications were identified using Medical Subject Headings (MeSH)-based search strategies, with citation counts and journal impact factors obtained from Web of Science. The analysis considered multiple bibliometric indicators, including publication counts, citation frequencies, author productivity, journal impact, country contributions, and publication languages. Over the study period, research output increased at a compound annual growth rate (CAGR) of 5.1%, peaking in 2021 with 13 publications. The average number of citations per year was 421.3, with a peak in 2013 (910 citations) and a citation CAGR of -23.9%, a pattern likely influenced by the shorter citation window of recent studies. Research activity was dominated by China and the United States, while no publications originated from Spanish-speaking countries despite the high regional prevalence of both conditions. These findings reveal a pronounced geographical imbalance in the literature, emphasizing the urgent need to stimulate research in underrepresented regions. Furthermore, the recent nomenclature transition from non-alcoholic fatty liver disease (NAFLD) to MASLD is expected to influence future bibliometric trends, requiring hybrid search strategies to ensure continuity in literature tracking during the transitional period.
    Keywords:  bibliometric analysis; hepatic steatosis (masld); nonalcoholic fatty liver disease (nafld); obstructive sleep apnea hypopnea syndrome; scientific publication indicators; visual analysis
    DOI:  https://doi.org/10.7759/cureus.90708
  12. Medicine (Baltimore). 2025 Sep 19. 104(38): e43953
       BACKGROUND: Major earthquakes are commonly visualized using Geographic Information Systems (GIS), with bubble maps scaled according to magnitude, depth, or casualty counts. This study investigates the hypothesis that countries most frequently mentioned in earthquake-related academic articles (CMEAs) correspond to those most impacted by significant seismic events.
    METHODS: Data on 27,100 major earthquakes (magnitude ≥ 5.5) from 1965 to March 2025 were obtained from the U.S. Geological Survey (USGS). Earthquake magnitudes were visualized using GIS bubble maps, and temporal trends were analyzed based on magnitude and year. In parallel, 24,974 earthquake-related articles published between 2015 and 2024 were retrieved from the Web of Science Core Collection (WoSCC). Ten key metadata elements were analyzed to identify the top 10 CMEAs. Kano diagrams were used to assess the relations between these countries, with articles mentions and publications, and those most affected by major earthquakes. Additionally, a bibliometric analysis using slope graphs was conducted to identify the most prominent article elements exhibiting upward publication trends.
    RESULTS: Key findings include the strongest earthquakes recorded were magnitude 9.1 events in Banda Aceh, Indonesia (2004), and off the coast of Tohoku, Japan (2011); earthquake frequency peaked in the years 2007 and 2010; China contributed the highest number of articles (6137; 24.57%), while the United States had the highest h-index (99 for the U.S. vs 78 for China); the correlation between the number of publications and the countries most severely affected by historical earthquakes was 0.232 (t = 1.167, P = .255), while the correlation between article mentions and those countries was 0.169 (t = 0.664, P = .517).
    CONCLUSION: This study does not support the hypothesis that countries most frequently discussed in earthquake-related literature correspond to those most affected by major earthquakes. However, the integrated use of hypothesis testing, slope graphs, Kano diagrams, and bibliometric summaries offers a robust framework for future research exploring publication trends in the context of natural disasters.
    Keywords:  Kano diagram; bibliometric analysis; earthquakes; geographic information system (GIS); natural disasters; research trends; slope graph
    DOI:  https://doi.org/10.1097/MD.0000000000043953
  13. Insights Imaging. 2025 Sep 27. 16(1): 210
       OBJECTIVE: To investigate the representation of women among the authors of top-cited articles published in the medical imaging literature.
    MATERIALS AND METHODS: This retrospective bibliometric study queried the Web of Science database to identify the top-cited articles (citation number ≥ 300) in the medical imaging literature. The gender of the first and last (senior) authors was determined based on online databases. The year of publication, country of origin, document type, and subspecialty for each article were also collected. We analyzed the proportion of women authors and the relationships between author gender and article characteristics.
    RESULTS: Among 596 top-cited articles, women accounted for 132 (22.1%) of first authors and 84 (14.1%) of last authors. Women as last authors were more likely to publish with women first authors compared to male first authors (odds ratio: 1.35). Women's first authorship was significantly more frequent in articles from South Korea (44.4%; phi = 0.095) and in radiation oncology (38.1%; phi = 0.106) and significantly less frequent in articles from France (0.0%; phi = -0.102). Women's last authorship was significantly more frequent in articles from the Netherlands (30.6%; phi = 0.120), in breast (38.9%; phi = 0.126), and in radiation oncology (28.6%; phi = 0.115), and significantly less frequent in nuclear medicine (4.3%; phi = -0.083).
    CONCLUSION: Women authors remain underrepresented in top-cited articles published in the medical imaging literature, with country of origin and subspecialty identified as factors of influence.
    CRITICAL RELEVANCE STATEMENT: Women are still underrepresented among the authors of the top-cited articles in the medical imaging literature. The findings highlight the gender disparities in the highest academic achievement in this biomedical field and provide valuable insight into this ongoing issue.
    KEY POINTS: Women authors remain underrepresented in top-cited articles in the medical imaging literature. Women accounted for 22.1% of first authors and 14.1% of last authors. There were variations in the proportion of women authors between countries and subspecialties.
    Keywords:  Imaging literature; Publications; Top-cited; Women authorship
    DOI:  https://doi.org/10.1186/s13244-025-02085-4
  14. Int Arch Otorhinolaryngol. 2025 Jul;29(3): 1-13
       Introduction: The quality of life of head and neck cancer patients is significantly impacted. Bibliometric analysis is crucial to get the scholarly landscape, figuring out the research area related to quality of life among head and neck cancer patients.
    Objective: To use network visualization mapping to perform a bibliometric analysis of the quality of life among head and neck cancer patients.
    Methods: A literature search was done using the Scopus database. The searched keywords among papers included the amalgamation of quality of life , and head and neck cancer . The data were extracted, and bibliometric analysis was performed based on the bibliometric indicators: the trend of article publishing, citations, leading countries, and institutions contributing to a publication, potential authors, journals, and frequently occurring keywords. Network visualization mapping was performed using the VOSviewer software (Leiden University).
    Results: A total of 366 articles met the predefined eligibility criteria and were selected for analysis. The selected papers were published in 57 journals between 1983 and 2024. The results provide insightful information on there being a maximum of 25 articles in 2022 and the highest citation count of 1,683 in 2001. Among 52 countries, the United States was the leading contributor, having published 75 articles. The top contributing institution was Liverpool University Hospital, Aintree, United Kingdom, with four articles. Roger Simon was the author with the most potential, and Head and Neck was an impactful journal. The most frequently occurring keywords were quality of life , head and neck , and oral cancer .
    Conclusion: The current bibliometric analysis identified the scholarly impact and characteristics of articles, which provide researchers and policymakers with baseline data to frame research strategies for improving quality of life among head and neck cancer patients.
    Keywords:  bibliometric analysis; head and neck cancer; network; quality of life
    DOI:  https://doi.org/10.1055/s-0045-1809665
  15. Brain Behav. 2025 Sep;15(9): e70881
       INTRODUCTION: Spinal cord injury (SCI), acknowledged as the most severe complication arising from spinal trauma, pertains to the dysfunction of the spinal cord due to traumatic events or other pathological conditions. Extensive research has elucidated a substantial correlation between SCI and inflammatory processes, highlighting the critical involvement of microglia in orchestrating neuroinflammatory responses. Moreover, a growing body of evidence has demonstrated a strong connection between microglial activation and both the pathogenesis and progression of SCI.
    OBJECTIVE: We chose bibliometric analysis to comprehensively summarize the research progress of microglia in SCI, aiming to provide researchers with current trends and future research directions.
    METHODS: All articles and reviews addressing microglia in SCI were systematically retrieved from the Web of Science Core Collection database, spanning publications from 2000 to 2024. Subsequent bibliometric analysis was conducted utilizing four analytical tools: VOSviewer (version 1.6.20), R software (package bibliometrix), the Biblioshiny web interface, and CiteSpace (version 6.2.R4), ensuring comprehensive examination of publication patterns and research trends.
    RESULTS: A total of 2428 publications were ultimately included in this bibliometric analysis. The annual publication count demonstrated a consistent upward trajectory. China is the country with the most published articles, and Ohio State University ranks first in institutional publications. Experimental Neurology is the journal with the most published articles, while Journal of Neuroscience is the journal with the most cited articles. Popovich Pg is the author with the highest productivity and co-citation. Cluster analysis yielded a total of 15 different co-citation clusters. Time analysis shows explosive citation outbreaks in 2006, 2009, and 2011. Keyword analysis revealed inflammation, expression, activation, and central nervous system as the most frequently occurring terms. Recent keyword trends feature emerging terms like exosomes, extracellular vesicles, and nanoparticles. Keyword bursts revealed promotes, extracellular vesicle, recovery, neuroinflammation, therapy, polarization, and pathway are the hotspots of research at the present stage and are likely to continue. These findings provide critical insights for developing microglia-targeted therapeutic strategies and prioritizing research directions in neuroinflammatory modulation to improve functional recovery after SCI.
    CONCLUSION: Emerging research frontiers prominently feature exosomes, gut microbiota, and nanoparticles. The interplay between microglia-mediated neuroinflammation and SCI has emerged as a critical focal point in current scientific investigations and is anticipated to remain central to forthcoming scientific inquiries.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; microglia; spinal cord injury
    DOI:  https://doi.org/10.1002/brb3.70881
  16. Front Neurol. 2025 ;16 1511655
       Background: Non-invasive neuromodulation (NIN) technology, a promising approach in the field of neuromodulation, has been employed to address a diverse array of disorders, with an increasing volume of research emerging. Traditional Chinese acupuncture has also been utilized as a complementary and preventive therapy for various ailments. Nevertheless, the publication trends and research hotspots at the intersection of acupuncture and NIN technology remain largely unexplored. This study aims to systematically analyze the publication trends and research hotspots related to the convergence of acupuncture and NIN over the past two decades using bibliometric methods.
    Methods: We collected literature data on the combination of acupuncture and NIN technology from January 1, 2004, to December 31, 2023, utilizing the Web of Science Core Collection (WOSCC) database. This data was imported into CiteSpace (version 6.2. R4) and RStudio to facilitate a visual analysis of research hotspots and trends, categorized by author, country/region, affiliation, annual publication, keywords, and journal.
    Results: A total of 803 articles were retrieved, encompassing contributions from 55 countries, 468 research institutions, and 360 academic journals. The People's Republic of China leads in publication volume with 390 articles, followed by Capital Medical University and Peking University, each contributing 27 articles. Among the authors, HAN JS has the highest number of co-citations, totaling 142. Additionally, the journal Evidence-Based Complementary and Alternative Medicine is noted for publishing the most papers in this field. Recent research hotspots regarding acupuncture combined with NIN technology primarily focus on topics such as "postoperative gastrointestinal function," "postoperative analgesia," "postoperative nausea and vomiting," "acupuncture analgesia," "reproductive medicine," "inflammation," "chronic low back pain," and "postoperative pain." The predominant intervention method identified is TEAS technology, which integrates acupuncture with modern electrical stimulation as an innovative clinical treatment approach.
    Conclusion: The publications on acupuncture combined with NIN technology have made significant progress; however, there is still a need to strengthen international academic exchanges and cooperation among scientific researchers and institutions to promote interdisciplinary collaboration and academic innovation. Furthermore, future studies should focus on enhancing the overall quality of research outcomes in this field and reinforcing research programs.
    Keywords:  acupuncture; analgesia; bibliometric; non-invasive neuromodulation technology; transcutaneous electrical acupoint stimulation; visualization analysis
    DOI:  https://doi.org/10.3389/fneur.2025.1511655
  17. Cureus. 2025 Aug;17(8): e90724
      Bladder cancer has traditionally relied on cystoscopy, which is invasive and associated with patient morbidity, prompting extensive research into non-invasive biomarkers specific to bladder cancer. This study aims to map the global research trends in bladder cancer biomarkers over the last two decades using bibliometric analysis methodology. A total of 1337 articles from 2004 to 2024 were retrieved from Web of Science Core Collection and analysed using the Bibliometrix R Package (K-Synth Srl, Naples, Italy) and VOSviewer (Centre for Science and Technology Studies, Leiden University, The Netherlands). Research output in this field has grown from 21 publications in 2004 to a peak of 138 in 2021. China is the most productive country with 516 (38.6%) publications, and Sun Yat-sen University in Guangzhou, China, is the most productive institution. However, Spain, the United Kingdom, and Japan demonstrated greater research impact with higher average citations per paper. Shariat, SF, and Lotan, Y, are the two most influential authors in this field based on average citations and network analysis. Keywords analysis revealed a shift in research trends from established protein-based biomarkers such as NMP22 and UroVysion (Abbott Laboratories, Chicago, Illinois, United States) to novel genetic and epigenetic markers. Future studies should foster greater international collaboration in translating these novel biomarkers into routine clinical practice.
    Keywords:  bibliometric analysis; biomarker; bladder cancer; research trends; urine
    DOI:  https://doi.org/10.7759/cureus.90724
  18. Int J Chron Obstruct Pulmon Dis. 2025 ;20 3255-3268
       Purpose: Chronic Obstructive Pulmonary Disease (COPD) is a major global health issue, significantly impacting healthcare systems. Effective nursing interventions are crucial for improving patient outcomes and reducing hospitalizations. This study conducts a bibliometric analysis of nursing interventions and research in the management of COPD to identify key trends, contributors, and emerging research directions.
    Material and Methods: We analyzed 1390 articles published before 2024, sourced from the Web of Science Core Collection (SCI-Expanded). Using R Bibliometrix, VOSviewer, and CiteSpace, we assessed publication trends, identified influential authors and institutions, and mapped research hotspots and collaborations. The analysis included quantitative metrics such as citation counts and co-citation networks, as well as qualitative assessments of thematic evolution.
    Results: The analysis revealed a significant increase in research output on COPD nursing interventions, particularly after 2001, with a peak in publications around 2021, likely due to the COVID-19 pandemic. The United States, the United Kingdom, and China were the top contributors, accounting for over 45% of the total publications. Key research hotspots included acute exacerbations, quality of life, evidence-based nursing, and pulmonary rehabilitation. The study highlighted a shift from symptom management to more holistic, patient-centered care models.
    Conclusion: This study emphasizes the critical role of nursing interventions in managing COPD and reducing its global burden. The identified research trends and emerging topics offer valuable insights for future research, underscoring the need for innovation in nursing practices and interdisciplinary collaboration. These findings aim to inform the development of more effective COPD nursing strategies and enhance clinical practice.
    Keywords:  bibliometric analysis; chronic obstructive pulmonary disease; nursing; patient-centered care; research trends
    DOI:  https://doi.org/10.2147/COPD.S543869
  19. Nurs Res Pract. 2025 ;2025 8836038
      Aim: The aim of this study is to explore the international landscape and hot topics within the field of wound, ostomy, and continence (WOC) nursing over recent years. Methods: Literature on WOC nursing published between 2012 and 2024 was retrieved from the Web of Science database. VOSviewer was employed as the primary tool, complemented by CiteSpace, to conduct a bibliometric analysis. This included examining collaborative networks at the author, institutional, and national levels, alongside keyword visualizations employing clustering, time zone diagram analysis, and emergence analyses. Results: An initial search identified 3474 publications. These were subsequently grouped into eight central clusters, encompassing the work of 6341 authors. Analysis revealed current research hotspots, including the field of pressure injury, ostomy management, wound management, incontinence, skin damage, therapy technology, nursing care, and telehealth. Conclusion: First, scientific research attention in the field of WOC nursing is not high. Second, the uneven development of WOC nursing is mainly reflected in the imbalance in the number of publications between journals and countries. Third, the research focus of WOC nursing is in the wound care sector, among which pressure injuries have always been a research hotspot.
    DOI:  https://doi.org/10.1155/nrp/8836038
  20. Shock. 2025 Sep 23.
       BACKGROUND: Metabolic reprogramming has emerged as a central mechanism in sepsis pathogenesis, influencing immune responses, organ dysfunction, and therapeutic outcomes. This study conducts a comprehensive bibliometric analysis to map the research landscape, identify key trends, and highlight future directions in this field.
    METHODS: Based on the Science Citation Index Expanded database in Web of Science Core Collection (WOSCC) database, we retrieved and analyzed 672 English-language original research articles and reviews. Using R-bibliometrix, VOSviewer, and CiteSpace we performed a multidimensional analysis of academic output trends, geographical distribution, institutional and author collaboration networks, burst detection and the evolution of research hotspots.
    RESULTS: The analysis reveals a consistent upward trend in both publication output and citation frequency within this research domain. The United States (24.3% of total publications) and China (23.4%) have emerged as the most productive contributing nations. Notably, the United States maintains superior academic influence as evidenced by its highest citation frequency. Among institutions, Wake Forest University in the United States holds a preeminent position, having published 54 high-impact articles in this field. The journals Frontiers in Immunology, Shock, and Critical Care, represent the premier academic platforms in this research domain. Immunometabolism, mitochondrial regulation, gut microbiota imbalance, epigenetic modifications, along with the mTOR/AMPK/HIF-1α axis and the Sirtuin family pathway has been identified as the key research hotspots. Novel therapeutic approaches targeting metabolic regulation are rapidly emerging, including pharmacological agents, natural compounds, stem cell-based therapies, and non-coding RNA interventions.
    CONCLUSION: Research on metabolic reprogramming in sepsis shows promising prospects, with investigations into key mechanisms focusing on current research hotspots and the development of metabolism-targeted interventions emerging as critical priorities for future sepsis prevention and treatment strategies.
    Keywords:  Glycolysis; Gut microbiota; Immunometabolism; Lactylation; Macrophage; Metabolic reprogramming; Mitochondria; Sepsis
    DOI:  https://doi.org/10.1097/SHK.0000000000002714
  21. Acad Radiol. 2025 Sep 26. pii: S1076-6332(25)00811-6. [Epub ahead of print]
       RATIONALE AND OBJECTIVES: Program Directors have responsibility for maintaining the academic focus and ensuring mentorship for the next generation of radiologists. The goal of this study was to identify the academic productivity and scholarly activity of Program Directors (PDs) of radiology residency programs in the U.S.
    MATERIALS AND METHODS: A list of all DR residency programs PDs was obtained from the American Medical Association (AMA) Residency and Fellowship Database. Academic productivity information about each PD was obtained from their publicly available Scopus profiles, or from PubMed if Scopus profile was unavailable. Metrics of scholarly activity were recorded including the number of publications and citations using median with interquartile ranges (IQR). The differences in number, citation count, and citation rate between first/last-author and co-author publications were analyzed using non-parametric univariate analysis. All individual publications were analyzed for predictors of citation count using a multivariable Poisson regression model of publication characteristics.
    RESULTS: Among the 195 PDs, the median h-index was 4 (IQR: 1-11; range: 0-61). The top 10th percentile (by h-index) of authors (n=20) contributed 40% [1620/4100] of all publications and 65% [61,105/94,577] of all citations. 18% (35/195) had one or no publication. Another 8% had a co-author publication, but no first/last author publication. In the previous 5 years, 8% of PDs on Scopus (11/136) had no publication, and 23% (31/136) had no first/last author publication. PDs with <20 years since graduation had significantly fewer publications (median 3 [1-10]), compared to PDs with >20 years since graduation (median 14 [6-37], P<0.001) in the previous 5 years.
    CONCLUSION: Scholarly activity in PDs of U.S. academic radiology programs is low, with top 10th percentile contributing significantly more towards overall publications and citations. The trends point towards lower scholarly productivity over time. Academic radiology leadership may need to address this as the future course is charted.
    Keywords:  Productivity; Program director; Radiology; Residency; Scholarly
    DOI:  https://doi.org/10.1016/j.acra.2025.08.042
  22. Pain Physician. 2025 Sep;28(5): 397-416
       BACKGROUND: Chronic low back pain (CLBP) is the leading cause of years lived with disability worldwide. Recent studies show increasing evidence for the implication of a multimodal treatment approach for CLBP, including education, exercise therapy, and physical activity.
    OBJECTIVE: This study aimed to analyze the trends in the biopsychosocial approach to CLBP through bibliometric analysis and to explore the main topics and provide recommendations for researchers and clinicians.
    STUDY DESIGN: In this bibliometric analysis, a 2-phase literature screening was performed to generate clusters and thus explore the main topics of the years 2012-2023.
    METHODS: Literature was derived from Web of Science for the years 2012-2023. Two researchers independently conducted double-blind title and abstract screening in accordance with PRISMA guidelines. VOSViewer and CiteSpace software were used to analyze authors, countries, institutions, journals, keywords, and references. The clusters of co-cited references generated by the CiteSpace software were analyzed, and the largest clusters related to the biopsychosocial approach were narratively reviewed in detail.
    RESULTS: A total of 2,070 studies were included in the analysis. The most influential country, institution, and author were the United States of America, the University of Sydney, and Leonardo Oliveira Pena Costa, respectively. BMC Musculoskeletal Disorders was the journal with the greatest number of publications. Exercise therapy, cognitive-functional therapy, pain neuroscience education, manual therapy, mobile applications, and psychologically informed physical therapy stood out in the reference analysis.
    LIMITATIONS: This study has several limitations, such as the restriction to studies indexed in the WOS database. Only English-language studies were included, and to maintain focus, we chose to discuss only those relevant to the biopsychosocial approach within the top 10 clusters.
    CONCLUSIONS: This bibliometric analysis highlighted the evolving trends and main contributors in this field. The study mapped the complex knowledge network in the field, highlighting various interventions as focal points of scientific interest, particularly exercise therapy, cognitive-functional therapy, pain neuroscience education, manual therapy, mobile application, and psychologically informed physical therapy. Standardization in research methodologies and more high-quality studies are needed to solidify the efficacy of these interventions and inform clinical practice more effectively.
    Keywords:   biopsychosocial; education; exercise; manual therapy ; telerehabilitation; low back pain
  23. ACS Omega. 2025 Sep 16. 10(36): 40726-40739
      This study presents a bibliometric analysis of scientific publications related to artificial intelligence (AI) in hydrogel-based 3D printing, aiming to map the research landscape, trends, and scholarly impact of this emerging interdisciplinary field. Data were retrieved from Scopus and Web of Science (WoS) databases covering the period from 2015 to early 2025. Analytical tools, including Excel, Pycharm, OriginPro, Bibilioshiny and VOSviewer, were applied to examine publication growth, document types, geographical distribution, institutional output, and citation patterns. The results reveal a sharp increase in research activity since 2020, with China and the United States leading in publication volume. Articles and reviews constitute the majority of document types, reflecting both foundational work and critical evaluations. Institutional contributions were dominated by Chinese and Indian universities, while citation analysis highlighted influential works on smart biomaterials and AI-assisted biofabrication. The findings offer a structured overview of the field's development and provide insights for researchers, policymakers, and practitioners aiming to navigate or contribute to this rapidly advancing domain.
    DOI:  https://doi.org/10.1021/acsomega.5c04479
  24. Acta Psychol (Amst). 2025 Sep 22. pii: S0001-6918(25)00934-5. [Epub ahead of print]260 105621
      This scientometric study presents a comprehensive analysis of the research landscape on mathematics anxiety from 2005 to 2024. Drawing on data from the Web of Science database, the study applies bibliometric techniques, co-citation analysis and thematic mapping to examine publication trends, influential sources, key contributors and the intellectual structure of the field. The findings reveal a growing body of interdisciplinary research exploring the cognitive, psychological and emotional dimensions of mathematics anxiety, along with an increasing focus on intervention strategies. Three major thematic clusters were identified: the impact of anxiety on students' performance, psychological and cognitive mechanisms and the role of emotions and self-perception. Citation network analysis highlights core contributions that have shaped the field, while thematic evolution shows a shift toward applied and motivational research. This study provides valuable insights for educators, researchers and policymakers, offering a foundation for future inquiry and the development of targeted strategies to reduce mathematics anxiety and improve educational outcomes.
    Keywords:  Bibliometric analysis; Co-citation analysis; Educational psychology; Mathematics anxiety; Scientometric analysis
    DOI:  https://doi.org/10.1016/j.actpsy.2025.105621
  25. Front Nutr. 2025 ;12 1650883
       Background: In recent years, the potential role of probiotics in modulating gut microbiota, enhancing immune function and improving metabolic diseases has become a highly field in biomedical and clinical research. The rapid increase in global probiotic clinical trials necessitates a systematic evaluation of current research status, developmental trends, and collaborative networks in this field.
    Purpose: This study employs bibliometric analysis to comprehensively evaluate research progress and hotspots in clinical applications of probiotics.
    Method: A systematic search was performed in the Web of Science database to collect articles and reviews regarding the clinical application of probiotics between 2000 and 2025. The retrieved records were analyzed using Microsoft Office Excel, Cite Space and VOS viewers.
    Result: During the period from 2000 to 2025, we retrieved a total of 3,674 papers related to the clinical application of probiotics, and the number of papers is showing a continuous growth trend. The research was mainly focused on North America, Western Europe, and East Asia, with the United States leading the way with 714 papers, high impact (H-index 107, total citations 44,833), and top institutions (Harvard Univ). Nutrition and microbiology are the main academic fields. The current research hotspots and development directions focus on the application of probiotics in diseases such as "inflammation", "obesity", "insulin resistance", "depression", "hyperlipidemia", and "cancer".
    Conclusion: This study represents the first application of bibliometric methods to systematically visualize and analyze research progress in the field of probiotic clinical applications, identifying key research trends and frontiers. The findings offer valuable insights for researchers at various career stages, particularly those new to the field, enabling them to identify critical developments and serving as a foundational reference for future clinical applications of probiotics.
    Keywords:  Cite Space; VOS viewer; bibliometrics; clinical application; probiotics; visual analysis
    DOI:  https://doi.org/10.3389/fnut.2025.1650883
  26. Digit Health. 2025 Jan-Dec;11:11 20552076251380652
       Background: Artificial intelligence (AI) has played an important role in the field of medical risk prediction with its strong learning ability and data processing capabilities. With the rapid development of research in this field, it is necessary to conduct quantitative literature analysis to understand the development trends and research hotspots of AI in the field of medical risk prediction.
    Objective: Through a comprehensive bibliometric analysis, this paper summarizes the development stage and key research hotspots of the application of AI in the field of medical risk prediction in the past 20 years. Additionally, we provide a thorough analysis of emerging trends and future directions, offering insights into how advancements in AI are likely to shape risk prediction methodologies and their clinical applications in the years to come.
    Methods: Relevant articles from the establishment of the database to 2024 were retrieved through Science Citation Index and Social Sciences Citation Index of the Web of Science Core Collection. Citespace, VOSviewer, Scimago Graphica, Pajek, and other software were used for bibliometric and visual analysis.
    Result: A total of 2080 articles were included. From 1986 to 2004, this field experienced a slow development period, with the number of papers published per year less than 10. From 2005 to 2020, the number of papers published increased with a linear trend, and entered an exponential rapid growth stage after 2020, with the development entering a mature stage. The United States was the country with the most extensive cooperation and the largest number of publications (652 articles, 31.35%). The diseases, AI technologies, and functions that have received the most attention in this field are cancer, machine learning, and prediction, respectively.
    Conclusions: Artificial intelligence in medical risk prediction has transitioned from technical exploration to a critical component of clinical practice, expanding from single-disease forecasts to complex, multimodal assessments. Advances in machine learning and personalized medicine have integrated AI into medical decision-making and management, yet widespread adoption requires addressing challenges related to interpretability, privacy, ethics, reliability, and standardization. In the future, AI is expected to significantly enhance prediction accuracy, optimize health management, and advance personalized medicine.
    Keywords:  Artificial intelligence; bibliometrics analysis; machine learning; predictive modeling; risk assessment
    DOI:  https://doi.org/10.1177/20552076251380652
  27. Holist Nurs Pract. 2025 Sep 22.
      Although yoga has become popular for women's health in recent years, little is known about its hotspots and global trends over time. The aim of the current study was to examine the bibliometric patterns of yoga research in women's health. The data were collected from the Web of Science (WoS) Core Collection database. Data analysis was performed by using WoS Core Collection, VOSviewer, and Bibliometrix package in R software. We performed co-occurrence and co-citation analyses. In total, 562 articles were reviewed. Overall, there were 2409 authors and 733 institutions from 48 countries that contributed to yoga research in the field of women's health. Cramer H. was the most prolific author with 16 articles. The most productive country was the US with 219 articles, and the most productive institution was the University of California with 79 articles. The first 10 keywords in this research area are women, health, exercise, yoga, depression, quality of life, physical activity, intervention, symptoms, and prevalence. The study will inform potential collaborators, countries, and institutions for prospective research. This study will also serve as a guide for researchers, practitioners, and academics in further studies including development of health policies; and evidence-based practice on yoga in women's health.
    Keywords:  Web of Science; bibliometrics; co-citation analysis; science mapping; yoga
    DOI:  https://doi.org/10.1097/HNP.0000000000000763
  28. Cureus. 2025 Aug;17(8): e90531
      This bibliometric analysis presents a comprehensive evaluation of the contemporary medical literature concerning dengue epidemiology, with a particular emphasis on its global impact in the 21st century. Utilizing an informetric approach, the study offers a systematic overview of the research landscape, identifying trends and driving factors influencing scholarly output in this domain. A dataset comprising 2,982 peer-reviewed publications from the past decade was curated from the Web of Science Core Collection, using the keyword "Dengue Epidemiology" to ensure thematic relevance. Subsequent analysis was conducted using VOSviewer version 1.6.20 software to generate visual mappings based on variables including country of origin, keyword co-occurrence, affiliated academic institutions, and publication venues. The dominance of research output from non-endemic regions suggests a shift in global interest, potentially reflective of the expanding geographic distribution of Aedes aegypti, the primary vector of the dengue virus. This expansion may be influenced by climate change, facilitated by anthropogenic factors such as industrialization and increased global mobility. The concentration of literature within the disciplines of infectious diseases and public, environmental, and occupational health underscores the public health relevance of this arbovirus. These findings suggest that globalization, climate change, and evolving vector ecology are reshaping the geographic and academic focus of dengue research. If current environmental and developmental trajectories persist, dengue may become increasingly prevalent in previously unaffected regions, reinforcing its emergence as a growing global health threat in the 21st century.
    Keywords:  arbovirus research; bibliometric analysis; climate change; dengue epidemiology; neglected tropical diseases (ntds)
    DOI:  https://doi.org/10.7759/cureus.90531
  29. Gut Pathog. 2025 Sep 26. 17(1): 72
       BACKGROUND: There is increasing evidence suggesting that the gut microbiota plays a key role in the development of insulin resistance (IR). Therefore, the present bibliometric study aimed to characterize the development trends and research hotspots of publications related to the gut microbiota and IR.
    METHODS: Publications on the gut microbiota and IR between 2015 and 2024 were retrieved from the Scopus database. Bibliometric analyses were conducted with the VOSviewer version 1.6.20 software program.
    RESULTS: The Scopus query (15 June 2025) retrieved 584 publications on the gut microbiota and IR. Most were research articles (n = 480, 82.19%), followed by reviews (n = 82, 14.04%). Output is highly skewed toward East Asia and North America, with China leading the list with 254 papers (43.49%), followed by the United States (96; 16.44%), Canada (44; 7.53%), and Germany (27; 4.62%). Term-cooccurrence mapping in VOSviewer (v1.6.20) of the 251 high-frequency keywords (≥ 15 occurrences) resolved three thematic clusters: Cluster 1 focused on the high-fat-diet gut-liver axis; Cluster 2 examined patient-centered epidemiology and clinical trials; and Cluster 3 investigated inflammatory and metabolic signalling.
    CONCLUSIONS: The annual number of publications on the gut microbiota and IR has increased rapidly in the past ten years, demonstrating that the gut microbiota and IR have the potential to be researched precisely and are attracting increasing attention. The findings of this study can help researchers explore new directions for future research in this area and could serve as a reference for future academic research.
    Keywords:  Bibliometric; Gut microbiota; Insulin resistance; Insulin sensitivity; Microbiome; Scopus; VOSviewer
    DOI:  https://doi.org/10.1186/s13099-025-00749-6
  30. Pharmaceuticals (Basel). 2025 Sep 21. pii: 1422. [Epub ahead of print]18(9):
      Background/Objectives: Large-scale bibliometric assessments of psoriasis pharmacotherapy research remain limited despite significant research output in this rapidly evolving field. This study aimed to map the evolution of systemic psoriasis therapy research over five decades and demonstrate how systematic analysis of research trajectories can illuminate the transformation of specialized medical fields into central components of precision medicine. Methods: A comprehensive bibliometric analysis was conducted using Web of Science Core Collection as the single data source, examining 19,284 publications spanning 1975-2025. The methodology employed AI-enhanced terminology normalization for standardizing pharmaceutical nomenclature, VOSviewer version 1.6.20 for network visualization, and Bibliometrix package for temporal trend analysis and thematic evolution mapping. International collaboration networks, thematic evolution across three distinct periods (1975-2000, 2001-2010, 2011-2025), and citation impact patterns were systematically analyzed. Results: Four distinct developmental phases were identified, with publications growing from 9 articles in 1975 to 1638 in 2024. The United States dominated research output with 5959 documents, while Canada achieved the highest citation efficiency at 62.65 citations per document. Global collaboration encompassed 70 countries organized into four regional clusters, with a 28-nation Asia-Pacific-Africa-Middle East alliance representing the largest collaborative group. Citation impact peaked during 2001-2008, coinciding with revolutionary biological therapy introduction. Thematic evolution demonstrated systematic transformation from two foundational themes to nine specialized domains, ultimately consolidating into four core areas focused on targeted therapeutics and evidence-based methodologies. Keyword analysis demonstrated progression from basic immunological studies to sophisticated targeted interventions, evolving from tumor necrosis factor alpha inhibitors to contemporary interleukin-17/interleukin-23 pathway targeting and Janus kinase inhibitors. Conclusions: Over five decades, psoriasis therapeutics research has shifted from a niche dermatological discipline to a central model for innovation in immune-mediated diseases. This evolution illustrates how bibliometric approaches can capture the dynamics of scientific transformation, offering strategic insights for guiding pharmaceutical innovation, shaping research priorities, and informing precision medicine strategies across inflammatory conditions.
    Keywords:  Python; VOSviewer; bibliometric analysis; psoriasis; psoriasis therapy; web of science
    DOI:  https://doi.org/10.3390/ph18091422
  31. Updates Surg. 2025 Sep 24.
      Since 2004, the European Society of Endocrine Surgeons (ESES) has hosted biennial congresses as a platform for presenting key research. However, the publication rate of abstracts presented at these congresses is unknown. We searched for full publications using titles and authors of abstracts presented orally or as posters at ESES congresses from 2004 to 2018. Abstract factors, such as type of study and number of patients, were investigated in relation to publication rate, journal impact factor, and citation rates of published studies. Out of 733 abstracts presented at ESES during this period, 207 (28%) were presented orally and 528 (72%) as a poster, Overall, 456 of the abstracts (62%) were published, with a median time of 11.4 months from the ESES congress to publication [range - 64.5 to 156]. The median number of citations per published abstract was 21 [range 0-821], the average annual citation rate was 2.3 [0-54], and the median journal impact factor was 2.2 [0-21.3]. The median number of patients included per study was small, accounting for 71.5 [range 1-22,580]. While factors predicting higher chances for publication were oral format (OR 5), 2006 and 2008 ESES congresses (OR 21 and 12.6, respectively), larger sample sizes, oral presentation format, native English authorship, and randomized trials had higher annual citation rates. While the publication rates of ESES congress abstracts are high, collaborative efforts to conduct multicentric prospective studies could increase the publication rate of abstracts and enhance the overall scientific impact of the ESES congresses.
    Keywords:  Abstracts; Congresses; European Society of Endocrine Surgeons; Publication rates; Research
    DOI:  https://doi.org/10.1007/s13304-025-02216-y
  32. Front Mol Biosci. 2025 ;12 1683864
       Objective: To systematically characterize the global research landscape of metabolism-related intraocular malignancies and to validate the robustness of findings through a multi-database comparative approach.
    Methods: Publications from January 1, 1990, to July 31, 2025, were retrieved from the Web of Science Core Collection (WoSCC). To ensure the stability and generalizability of results, equivalent searches were performed in Scopus and PubMed, applying the same keyword set, time frame, and eligibility criteria. Bibliometric analyses were conducted using VOSviewer, CiteSpace, and GraphPad Prism to evaluate publication trends, geographic and institutional contributions, journal and author influence, keyword co-occurrence, co-citation patterns, and emerging research fronts. Cross-database validation assessed concordance in temporal trends, thematic focuses, and country rankings.
    Results: A total of 1,745 WoSCC publications were included, authored by researchers from 69 countries. Global output has increased markedly since 2010, peaking in 2021. Uveal melanoma consistently emerged as the dominant intraocular tumor type in metabolic research. Major thematic clusters encompassed oxidative stress, apoptosis, hypoxia, lipid metabolism, and metabolic reprogramming, with recent shifts toward long noncoding RNA, immune infiltration, and metabolomics, signaling a transition to precision oncology. Importantly, multi-database validation demonstrated high concordance in annual publication trends, as well as strong overlap in top keywords and stability in geographical and disease foci.
    Conclusion: This study provides a multi-database bibliometric assessment of metabolism-related intraocular malignancy research, with offering a reliable foundation for guiding future basic and translational research in ocular oncology.
    Keywords:  bibliometric analysis; intraocular malignancies; metabolism; precision oncology; uveal melanoma
    DOI:  https://doi.org/10.3389/fmolb.2025.1683864
  33. J Endod. 2025 Sep 23. pii: S0099-2399(25)00586-2. [Epub ahead of print]
       INTRODUCTION: Understanding root canal anatomy is fundamental for successful endodontic treatment. This bibliometric study aimed to identify and analyze the 100 most-cited articles related to root canal morphology to discover research trends, influential publications, and methodological progress in the field.
    METHODS: Data were extracted from the Scopus® database using the search terms "root canal anatomy" OR "root canal morphology" AND NOT "Preparation," with selection finalized on July 28, 2025. Articles were manually screened, and only English-language original research related to human teeth was included. Citation counts, publication years, journal names, countries of origin, study designs, and methodologies were analyzed.
    RESULTS: Most of the top-cited studies were published in the Journal of Endodontics (JOE) and International Endodontic Journal (IEJ), which together contributed 80% of the articles. Cone-beam computed tomography (CBCT) was the most used method, followed by dye-injected decalcified teeth and micro-computed tomography (μCT). The most frequently studied teeth were mandibular and maxillary first molars. Geographically, the United States, Brazil, and China led in publication output. Notably, there were no articles from Africa, highlighting a potential area for collaborative development. Over time, research has shifted from invasive in vitro techniques to advanced non-invasive imaging. The most-cited article was Vertucci's 1984 classification study, which remains widely used today.
    CONCLUSIONS: This bibliometric analysis delivers a comprehensive overview of influential studies in root canal anatomy, offering insights into global research patterns and technological advancement.
    Keywords:  CBCT; Root canal anatomy; Vertucci’s classification; bibliometrics
    DOI:  https://doi.org/10.1016/j.joen.2025.09.010
  34. Int J Emerg Med. 2025 Sep 26. 18(1): 171
      A bibliometric analysis was performed on academic research from 1965 to 2025 with a focus on S-100B protein and acute ischemic stroke (AIS). In total 15,792 academic papers about S-100B protein and AIS were reviewed, showing a sharp incline in publications after 1980. Leading the publications of research and citations were the United States, followed by Japan and Germany, which also had the highest clustered connections as well. The most prevalent organization was the Harvard University. This bibliometric analysis aims to analyze the prognostic value of S-100B protein as a potential biomarker in AIS with global data.
    Keywords:  Acute ischemic stroke; Bibliometric analysis; Biomarkers; S-100B
    DOI:  https://doi.org/10.1186/s12245-025-01007-x
  35. Future Sci OA. 2025 Dec;11(1): 2561355
       BACKGROUND: Hepatocellular carcinoma, a prevalent malignancy, threatens global health. Traditional Chinese medicine is widely applied in liver cancer treatment. This study assesses traditional Chinese medicine research trends and hotspots in this field through bibliometric analysis.
    METHODS: Publications related to traditional Chinese medicine and liver cancer from 2011 to 2023 were retrieved from the Web of Science Core Collection (WoSCC) database, and bibliometric analysis was conducted using VOSviewer, CiteSpace, and the R-bibliometrix.
    RESULTS: A total of 446 articles, led by China, were included, and the number of articles related to traditional Chinese medicine and liver cancer has been increasing year by year. Guangzhou University of Chinese Medicine and Shanghai University of Traditional Chinese Medicine are the main research institutions. Among the authors of these articles, Chen Yan has published the most papers, and JEMAL A has the most citations. Evidence-Based Complementary and Alternative Medicine is the most popular journals in this field and is also the most co-cited journal. Research focuses on integrating traditional Chinese medicine with modern medicine, with emerging hotspots including therapy, analysis systems, nanoparticles, and activation.
    CONCLUSIONS: This first comprehensive bibliometric analysis clarifies research frontiers and guides future directions in liver cancer and Chinese herbal medicine studies.
    Keywords:  Liver cancer; bibliometric analysis; research trends; traditional Chinese medicine; web of science
    DOI:  https://doi.org/10.1080/20565623.2025.2561355
  36. Medicine (Baltimore). 2025 Sep 19. 104(38): e43960
       OBJECTIVES: Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic ailment marked by the ossification and calcification of ligaments and their attachments, primarily affecting the elderly populace. Its manifestation often engenders intricate and diverse complications, easily eluding detection in clinical settings. The risk factors associated with DISH exhibit considerable variability, mirroring the disease's multifaceted pathogenesis. Through bibliometric analysis, this study delved into DISH's research focal points and trends, offering credible insights and avenues for future inquiry.
    METHODS: In this study, we retrieved original articles and reviews about DISH published on Web of Science Core Collection between 2000 and 2023. VOSviewer and CiteSpace were used to conduct the bibliometric and knowledge map analysis.
    RESULTS: A total of 515 original articles and reviews published in 200 academic journals by 2347 authors from 770 affiliations in 56 countries/regions were retrieved. The United States was the largest contributor. The Utrecht University was a leader in relevant research. Verlaan Jorrit-Jan was the most published authors. Spine published most DISH related articles. The preeminent areas of scholarly inquiry concerning the DISH were centered around diagnosis and prevalence, exploration of risk factors and associated comorbidities, and strategies for management and treatment.
    CONCLUSION: DISH presents as a systemic disease characterized by intricate and multifaceted causative factors and complications. Future research endeavors are poised to delve into its diagnosis, incidence rates, associations with other diseases, and the development of effective management and treatment strategies.
    Keywords:  bibliometric; comorbidities; diagnosis; diffuse idiopathic skeletal hyperostosis; prevalence; treatment; visualization
    DOI:  https://doi.org/10.1097/MD.0000000000043960
  37. Cureus. 2025 Aug;17(8): e90629
      The United Arab Emirates (UAE) has made significant strides in health-related research over the past decades. However, it is essential to monitor and review the status of health research to sustain progress. This study evaluates the UAE's health research landscape within the Gulf Cooperation Council (GCC) context and the broader Arab region. Bibliometric data on health research publications and clinical trials were reviewed from 1998 to mid-2024. Insights from regional analyses, including citation metrics, publication rates, and collaborative outputs, were integrated. Key challenges, such as funding limitations, regulatory barriers, and the decline in citation rates, were assessed to provide recommendations for improvement. The UAE has established itself as a key contributor to health research within the GCC, demonstrating significant progress in publication output and impact. While international collaborations have played a crucial role in enhancing visibility, there are areas for improvement, particularly in maintaining research influence and citation rates. To sustain progress, the UAE must prioritize high-impact collaborations, enhance research visibility, and invest in emerging areas like digital health and personalized medicine. Strategic reforms are essential to achieving a competitive health research ecosystem.
    Keywords:  bibliometric analysis; clinical research productivity; health sciences research; medical research uae; research collaboration; research trends in the uae (1998-2024)
    DOI:  https://doi.org/10.7759/cureus.90629
  38. Vascular. 2025 Sep 23. 17085381251379114
      BackgroundAortic diseases, including aneurysms and dissections, represent a significant global health burden, necessitating advancements in surgical and endovascular interventions. This bibliometric analysis examines the evolution of research trends, key contributors, and emerging themes in the treatment of aortic diseases over the past three decades.MethodsBibliometric data from Scopus and Web of Science databases were analyzed for peer-reviewed articles published between 1994 and 2024. A systematic approach adhering to the PRISMA 2020 framework identified 2985 articles. Descriptive and advanced bibliometric techniques, including citation, co-authorship, and keyword co-occurrence analyses, were employed using tools such as VOSviewer and Biblioshiny.ResultsThe annual scientific output demonstrated consistent growth, with significant contributions from the United States, United Kingdom, and Germany. Leading institutions, including Harvard Medical School and Beth Israel Deaconess Medical Center, played pivotal roles in advancing research. Keywords revealed a dual focus on minimally invasive techniques, such as EVAR and TEVAR, and patient-centered outcomes like quality of life and survival. Collaboration networks and citation analyses highlighted influential authors and foundational studies shaping the field.ConclusionsThe study underscores the importance of global collaboration and technological innovation in advancing aortic disease treatment. While disparities in research representation persist, emerging trends in hybrid approaches, multidisciplinary methods, and outcome-based studies offer promising directions for future research. These findings provide a comprehensive resource for clinicians, researchers, and policymakers seeking to address challenges and improve patient care in this critical field.
    Keywords:  Aortic diseases; aortic aneurysm; aortic dissection; bibliometric analysis; citation analysis; collaborative networks; minimally invasive surgery; open surgical repair; patient outcomes; research trends; vascular surgery
    DOI:  https://doi.org/10.1177/17085381251379114
  39. F1000Res. 2025 ;14 234
       Background: Women's studies in Latin America are transcendental because they make visible and challenge gender inequalities to achieve a more just and equitable society. However, despite this, there are still many research gaps, for which the objective is to examine the trends in research on women's studies in Latin America.
    Methods: An exploratory methodology based on bibliometric analysis is proposed to evaluate the scientific literature, based on the parameters of the PRISMA-2020 declaration.
    Results: The bibliometric analysis reveals a growth in women's studies in Latin America, reflecting its importance and relevance. Scientific production has experienced exponential growth, with leading researchers and journals. The United States and Canada lead scientific production. A change is observed in the topics addressed, focusing more on gender and equality. The thematic clusters identified highlight priority areas such as politics, institutions and representation.
    Conclusions: Emerging keywords include neoliberalism, gender violence, political participation, female empowerment, and femicide, reflecting new concerns and challenges addressed in gender studies in Latin America.
    Keywords:  Female empowerment; Female entrepreneurship; Gender inequality; Gender violence; Just society; Neoliberalism; PRISMA-2020.; Political participation
    DOI:  https://doi.org/10.12688/f1000research.159117.3
  40. Front Oncol. 2025 ;15 1619346
       Background: Breast cancer continues to be a leading cause of cancer-related deaths among women worldwide. Despite advancements in diagnostics and therapies, challenges such as metastasis, recurrence, and resistance remain prevalent. Recently, research has shifted from traditional genomic analyses to the study of epigenetic regulation, which includes DNA methylation, histone modifications, and non-coding RNAs. Given the rapid expansion of literature in this field, a systematic overview of its evolution and emerging trends is necessary.
    Methods: We performed a comprehensive bibliometric analysis of 5,271 articles on breast cancer epigenetics, sourced from the Web of Science Core Collection, covering the years 2000 to 2024. Utilizing tools like CiteSpace and VOSviewer, with support from RStudio, Pajek, and HisCite, we analyzed co-citation networks, keyword co-occurrence, and burst detection. This analysis included visualizations of collaboration among authors, institutions, and countries. Metrics such as modularity, silhouette scores, and betweenness centrality were used to ensure analytical rigor and to identify thematic evolution and emerging research frontiers.
    Results: From 2000 to 2018, the number of annual publications increased steadily, with citation peaks occurring in 2021. The United States led in research output and influence, followed by China. Leading institutions included Johns Hopkins University and the University of Texas MD Anderson Cancer Center. Keyword and co-citation analyses revealed four research phases: (1) early studies focused on promoter hypermethylation of tumor suppressor genes like RASSF1A; (2) an in-depth investigation of molecular mechanisms, including epithelial-mesenchymal transition and chromatin remodeling; (3) translational research involving HDAC inhibitors and DNA methylation biomarkers; and (4) recent advancements in multi-omics integration, synthetic lethality, and the study of epigenetics in the tumor microenvironment. Emerging research directions include the targeted removal of epigenetic memory, metabolism-epigenetics networks, and single-cell epigenomic profiling.
    Conclusion: This bibliometric study outlines the trajectory of research in breast cancer epigenetics, highlighting its evolution from basic methylation studies to advanced therapeutic exploration. Future research should focus on targeting epigenetic memory to combat drug resistance and recurrence, developing synthetic lethality strategies, and employing single-cell technologies for dynamic epigenetic mapping. These findings provide a strategic roadmap for researchers and policymakers navigating the evolving landscape of breast cancer epigenetics.
    Keywords:  VOSviewer; bibliometric; bibliometric study; breast cancer; citespace; epigenetics; visualization
    DOI:  https://doi.org/10.3389/fonc.2025.1619346
  41. Eur Burn J. 2025 Sep 09. pii: 51. [Epub ahead of print]6(3):
       BACKGROUND: Chemical burns represent a persistent global health challenge due to their high prevalence, causing lifelong disabilities and socioeconomic burdens. Although research on chemical burns has expanded over the past century, no comprehensive study has mapped the intellectual structure, global collaboration patterns, and thematic evolution of scientific production on chemical burns to determine how research in the area has evolved and the existence of gaps or imbalances that need to be addressed.
    OBJECTIVE: The aim was to analyze the scientific production on chemical burns using bibliometric methods, identifying key contributors, evolving themes, and research gaps.
    METHODS: Eligible documents contained the MeSH descriptor and were listed both in PubMed (1946 to 2024) and in the Web of Science Core Collection. The documents were analyzed with Bibliometrix version 5.0 and VOSviewer version 1.6.20. The metrics included were annual productivity, citation networks, co-authorship patterns, and keyword co-occurrence.
    RESULTS: The analysis included 3943 articles from 757 journals. The annual average was 25.8 articles, with a growth rate of 0.65% from 1946 to 2024. The USA produced the most articles (n = 1547), followed by China (n = 890). The USA also led in international collaboration, working with 26 countries. Harvard University was the leading institution (n = 325) and Burns the leading journal (n = 306), followed by Cornea (n = 132). The most common subject category of the research was surgery (n = 1185 docs) and ophthalmology (n = 984). Reim M. was the most prolific author (n = 35), while Basu S. had the most citations (n = 1159). The main clinical MeSH descriptors were "Eye burns" (n = 1158), "Esophageal stenosis" (n = 683), and "Caustics" (n = 659).
    CONCLUSIONS: The results show slight growth in scientific production on chemical burns. The USA and China are leading research in this field, and the main reported finding was eye burns.
    Keywords:  burns; chemical burns; eyes burns; injury; management
    DOI:  https://doi.org/10.3390/ebj6030051
  42. Front Aging Neurosci. 2025 ;17 1624420
       Background: Mild Cognitive Impairment in Parkinson's disease, a common non-motor symptom of Parkinson's disease, significantly impacts individuals' quality of life and predicts dementia risk, underscoring its clinical research importance. This study aimed to characterize the global bibliometric landscape and identify research hotspots, knowledge gaps, and future trends in the PD-MCI field over the past two decades using bibliometric and visualization methods.
    Methods: Literature related to PD-MCI published between 2005 and 2024 was retrieved from the Web of Science Core Collection database. Tools such as CiteSpace and VOSviewer were employed for visual analysis of annual publication volume, country/institutional distribution, author collaborations, journal co-citations, and keyword co-occurrence and bursts, constructing knowledge maps.
    Results: Mild cognitive impairment in Parkinson's disease research demonstrated significant growth, with sustained increases in annual publication volume and citation frequency. The United States dominated the field, while research output from countries like China grew rapidly. Research hotspots evolved from early explorations of molecular mechanisms toward clinical and translational studies focusing on neuroimaging, biomarkers, application of MDS diagnostic criteria, non-motor symptoms, and cognitive subtypes. Recently, machine learning, multi-omics integration, neuroinflammation, and mitochondrial function have emerged as new frontiers.
    Conclusion: Mild cognitive impairment in Parkinson's disease research has progressed from basic mechanism exploration to a multidisciplinary, integrated clinical-basic stage, following an evolutionary path of "pathological mechanism - clinical phenotype - biomarker - intervention strategy." Future research should focus on unifying diagnostic criteria, deepening understanding of multifactorial pathological mechanisms, developing precise biomarker combinations, and exploring individualized intervention strategies to achieve early warning and disease modification for PD-MCI.
    Keywords:  Mild Cognitive Impairment; Parkinson’s disease; bibliometric analysis; research frontiers; visualization analysis
    DOI:  https://doi.org/10.3389/fnagi.2025.1624420
  43. Virol J. 2025 Sep 26. 22(1): 302
       BACKGROUND: Over the past four decades, the relationship between viruses and gastrointestinal (GI) mucosal immunity has gained increasing attention due to frequent viral epidemics.
    OBJECTIVE: This study explores current research trends and future directions in this field through bibliometric analysis.
    METHODS: Literature from January 1, 1985, to December 31, 2024, was retrieved from the Web of Science Core Collection (WoSCC) on January 6, 2025. Analyses were conducted using VOSviewer, Citespace, and the Bibliometrix R package.
    RESULTS: A total of 4,842 publications were identified, with an annual growth rate of 8.65%. The United States (USA) led with 1,866 articles (38.54%), followed by China (794, 16.4%). The University of California was the leading institution (n = 605). Dandekar S was the most productive author (46 publications, H-index = 26). Major co-citation clusters focused on "HIV infection," "Infected macaque," and "CoV-2 infection." Mattapallil JJ et al. (2005) had the strongest citation burst (burst = 47.09). "HIV" appeared the most frequently among keywords (n = 640), followed by "mucosal immunity" (n = 340) and "vaccine" (n = 184). Keyword and citation burst analyses revealed longstanding focus on the pathogenesis of human immunodeficiency virus (HIV) and antiretroviral therapy (ART), influenza, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human papillomavirus (HPV)-related disease prevention and early diagnosis, the role of the gut microbiome in antiviral defense, and the pathogenesis and prognostic prevention of inflammatory bowel disease (IBD).
    CONCLUSION: This bibliometric analysis provides insights into research trends and emerging hotspots in the field of viruses and GI mucosal immunity, aiding researchers in identifying key areas for future investigation.
    Keywords:  Gastrointestinal tract; HIV; Hotspots; Mucosal immunity; Trends; Virus
    DOI:  https://doi.org/10.1186/s12985-025-02929-x
  44. J Asthma Allergy. 2025 ;18 1297-1309
       Purpose: Pediatric allergic conjunctivitis (PAC) is a prevalent inflammatory eye condition caused by hypersensitivity to allergens. This study performs a scientometric assessment to uncover global research patterns, collaboration networks, and thematic evolution in PAC literature.
    Methods: Publications related to PAC from 1963 to 2025 were retrieved from the Web of Science Core Collection database. Data were analyzed and visualized using VOSviewer (version 1.6.20), CiteSpace (version 6.3.R1), and the "bibliometrix" package in R (version 4.3.3).
    Results: A total of 378 documents were analyzed, revealing a significant increase in publications over the years, especially after 2010. China led with 99 publications, followed by the USA and Japan. Notable international collaboration was observed, particularly between China and Germany. China Medical University Taiwan, Sun Yat Sen University, and China Medical University Hospital Taiwan were identified as the leading institutions. The journal Pediatric Allergy and Immunology was the most prolific, followed by Allergy. The most cited authors included Wei CC and Lin CL, with key research themes encompassing asthma, rhinitis, and pediatric allergic diseases. Keyword analysis indicated a growing interest in environmental factors such as air pollution and the comorbidity of PAC with other allergic conditions.
    Conclusion: This bibliometric analysis offer valuable insights for future research directions and clinical strategies aimed at enhancing PAC diagnosis and treatment. Future research should evaluate the long-term efficacy of immunotherapy and investigate environmental determinants in PAC pathogenesis. Special emphasis is needed on multicenter studies incorporating regional diversity and standardized methodologies. Diverse regional data was incorporated to enhance global applicability and reduce public health burdens.
    Keywords:  allergic diseases; bibliometrics; environmental factors; pediatric allergic conjunctivitis; research hotspots
    DOI:  https://doi.org/10.2147/JAA.S541706
  45. Discov Oncol. 2025 Sep 26. 16(1): 1720
       PURPOSE: Triple-negative breast cancer (TNBC) is an aggressive subtype with poor outcomes. Antibody-drug conjugates (ADCs), linking monoclonal antibodies to cytotoxic payloads, show promise as targeted therapies. Despite growing interest, bibliometric studies on ADCs in TNBC are limited. This study aims to fill this gap by identifying key research trends, emerging areas, and clinical applications within the field of ADCs in TNBC.
    METHODS: A comprehensive search of 492 publications on ADCs for TNBC, published between 2010 and 2024, was conducted using the Web of Science Core Collection. Bibliometric analysis was performed using CiteSpace, VOSviewer, and Bibliometrix, and core journals were identified via Bradford's Law.
    RESULTS: The analysis revealed a continuous and steady increase in the number of articles published in this field over the past decade. Significant advancements in this field have been achieved by the United States, with Harvard Medical School being the most prolific institution, publishing 40 papers. Dr. A. Bardia from the United States was identified as the leading author, with 28 articles. The journal "Cancer Research" emerged as the most cited publication. By utilizing keyword co-occurrence and clustering analyses, current studies have pinpointed treatment strategies and diseases prognosis as key areas of focus. The dual-map overlay of journals indicates a gradual shift in research trends from biochemistry and genetic studies to immunology and clinical research. The development of next-generation ADCs (e.g., Dato-DXd, SKB264) holds the potential to transform TNBC therapeutics, particularly for tumors with heterogeneous target expression.
    CONCLUSION: This study provides valuable insights into the current research status, recent advancements, and emerging trends in ADCs for TNBC, offering data support for the precise classification and treatment of TNBC.
    Keywords:  Antibody-drug conjugates; Bibliometrics analysis; Triple-negative breast cancer; Visualization
    DOI:  https://doi.org/10.1007/s12672-025-03426-x
  46. Orphanet J Rare Dis. 2025 Sep 24. 20(1): 489
       PURPOSE: To conduct a visualization analysis of macrodactyly research from 2005 to 2024, providing a comprehensive overview of research trends, key contributors, and emerging topics.
    METHODS: A visual analysis of macrodactyly related publications from 2005 to 2024 was conducted using the Web of Science Core Collection database. Publication trends, country and institutional contributions, author collaboration networks, and keyword co-occurrences were analyzed. Statistical analysis and visualization were performed using Microsoft Excel, R, VOSviewer, and CiteSpace.
    RESULTS: One hundred and fifty-three publications were included. Annual publication trends showed fluctuations but an overall growth in interest over time, with notable growth from 2011 to 2014 peaking at 15 publications in 2014. The United States led with 128 publications, followed by China (60), Italy (40), Japan (36), and Turkey (27), with prominent institutions such as Mayo Clinic and Harvard University playing pivotal roles. Key authors like Dr. Marybeth Ezaki, working with the team at Texas Scottish Rite Hospital for Children, made substantial contributions to establishing diagnostic frameworks. Most importantly, keyword analysis revealed a fundamental shift in research focus from clinical and surgical themes (represented by keywords such as "foot," "hand," and "osteotomy" in early periods) to molecular and genetic investigations (characterized by "PIK3CA," "activating mutations," and "overgrowth" in recent years). The strongest citation burst was "overgrowth" (2016-2020), followed by genetic-related terms, with "activating mutations" representing the most recent trend (2020-2024), indicating increasing emphasis on PIK3CA mutations as the current research hotspot.
    CONCLUSION: This study highlights the evolution of macrodactyly research and reveals fluctuating publication trends and substantial contributions from key countries, authors, and institutions. The transition from clinical and surgical approaches to molecular and genetic investigations underscores advancements in the field. Future research should prioritize integrating genetic findings with clinical applications and advancing diagnostics and treatment strategies.
    Keywords:  Hotspot; Macrodactyly; Management; Overgrowth; Visualized
    DOI:  https://doi.org/10.1186/s13023-025-04011-9
  47. Front Microbiol. 2025 ;16 1634803
       Background: Metabolic endotoxemia, characterized by chronic low-grade elevation of circulating bacterial endotoxins such as lipopolysaccharides derived from Gram-negative bacteria, has emerged as a central focus in metabolic disease research. Notably, emerging evidence highlights the pivotal role of gut microbiota in driving this condition, though critical knowledge gaps persist regarding the precise mechanisms mediated by gut microbiota-derived metabolites and their specific signaling pathways, as well as the development of individualized intervention strategies. To systematically map the evolving research landscape, this review employs bibliometric analysis to identify emerging trends and patterns in understanding the interplay between metabolic endotoxemia and gut microbial communities.
    Materials and methods: This study employed a comprehensive bibliometric analysis of scholarly literature indexed in the Web of Science Core Collection (1900-2024) to investigate research patterns in metabolic endotoxemia and gut microbiota. Through multidimensional examination using VOSviewer, CiteSpace, the bibliometrix R package, and the online bibliometric analysis platform (https://bibliometric.com/), we systematically mapped research priorities, collaborative networks, and evolving frontiers in this interdisciplinary field. The methodology incorporated advanced visualization techniques and quantitative assessments to identify thematic clusters, institutional contributions, and knowledge diffusion pathways within the extant literature corpus.
    Results: This comprehensive global analysis, encompassing 1,585 relevant studies, demonstrates compelling evidence that China and USA collectively contribute over 50% of scientific output in this specialized research domain. Notably, academic investigations into metabolic endotoxemia and gut microbiota continue to maintain substantial research momentum. Current scholarly discourse prominently features five key thematic clusters: gut dysbiosis, intestinal barrier, risk, gut-liver axis, and short-chain fatty acids.
    Conclusion: This in-depth review systematically examines the evolving research landscape and emerging investigative priorities in metabolic endotoxemia and gut microbiota. It equips researchers with a comprehensive overview of key contributors in these specialized fields, including leading nations, institutions, academic journals, and potential collaborative networks. The analysis further delineates cutting-edge research frontiers and proposes strategic directions for future investigation, thereby serving as an invaluable resource for scholars navigating the complex interplay between metabolic endotoxemia and gut microbiota in the intestinal ecosystem.
    Keywords:  bibliometric analysis; gut microbiota; hotspots; metabolic endotoxemia; research trend
    DOI:  https://doi.org/10.3389/fmicb.2025.1634803
  48. Polymers (Basel). 2025 Sep 13. pii: 2480. [Epub ahead of print]17(18):
      This systematic bibliometric review, conducted in accordance with the PRISMA methodology, examines the literature on waste rubber tyres (WRTs) and their applications, measuring correlations between several standard metrics and identifying gaps that may stimulate new research. Using a thirty-year database from Scopus, both numerical and graphical results highlight key aspects, including geographic distribution, journal analysis, keywords, and three main research categories: environment, application, and property. Publications have grown exponentially at a rate of 17% per year. Research is concentrated in India and China, with Africa and Central America lagging behind. The United States leads in impact, while publication volume correlates moderately with gross domestic product (GDP), but negatively with international collaboration. Notably, several leading countries in automobile and tyre production have a limited academic presence in WRT research. The most prominent studies focus on material development; however, there remains a lack of practical applications for these materials. Recent trends show growing interest in WRTs within engineering, materials science, and environmental science, with multidisciplinary approaches emerging. A keyword analysis indicates a steady evolution in end-of-life tyres (ELT) research over recent years. In environmental studies, interest in ELT recycling methods has grown, though aspects such as toxicity, life cycle analysis, and leaching remain relatively unexplored. In terms of applications, research is primarily focused on pavements, while areas such as facades, blocks, and roofs remain under-studied. Finally, in material property studies, most research addresses compressive strength, while critical areas such as fire resistance, impact resistance, and thermal testing offer promising avenues for future research.
    Keywords:  bibliometric analysis; building materials; concrete; construction materials; crumb rubber tyre (CRT); end-of-life tire or tyre (ELT); waste rubber tyre (WRT)
    DOI:  https://doi.org/10.3390/polym17182480
  49. Endocr Metab Immune Disord Drug Targets. 2025 Sep 18.
       INTRODUCTION: In recent years, the prevalence of nonalcoholic steatohepatitis (NASH) has been rising globally. NASH has been linked to liver fibrosis, cirrhosis, hepatocellular carcinoma (HCC), and liver transplantation (LT), with the progression and severity of NASH closely impacting patients' prognosis. This increasing incidence highlights the urgent need for effective therapeutic strategies and early detection methods to mitigate the progression of the disease and improve patient prognosis. Accumulating evidence indicates that NASH and diabetes mellitus (DM) are interconnected and mutually affect each other. This study utilized bibliometric analysis to assess current publication trends and focal points in the links between NASH and DM, aiming to promote research in this area.
    METHODS: We thoroughly searched the Science Citation Index-Expanded (SCI-E) of the Web of Science Core Collection (WoSCC), PubMed, and the Excerpta Medica Database (Embase) to identify relevant articles on the links between NASH and DM from 2004 to 2023. The current publication trends and hotspots in this field were analyzed using the Online Analysis Platform of Literature Metrology, CiteSpace software, VOSviewer, and the R package Bibliometrix.
    RESULTS: From 2004 to 2023, 943 articles were found that focused on the links between NASH and DM with a noticeable surge in publications since 2015. The United States has taken the primary position in terms of the number of publications. It has also been the most active country in international collaborative efforts. The University of California, San Diego, and Kenneth Cusi were the most productive institution and scholar, respectively. The co-citation keywords cluster labels revealed 10 primary clusters: adiponectin, MAFLD, mortality, NASH, nonalcoholic fatty liver, SGLT2, neurodegeneration, LY2405319, autophagy, and hepatocytes. Recent studies focused on weight loss, fibrosis stage, NAFLD, mortality, and diabetes mellitus.
    DISCUSSION: Research on NASH and DM has transitioned from early mechanistic exploration to a current focus on weight management, diabetes control, and fibrosis prevention, particularly through lifestyle interventions and antidiabetic drug therapy. Future studies should integrate lifestyle adjustments with drug development, enhance international cooperation to fill regional research gaps, and achieve more effective management of NASH and DM.
    CONCLUSION: Over the past 20 years, global publications on the relationship between NASH and DM have grown rapidly. The current research hotspots focus on weight loss, and the reduction of blood glucose and fibrosis in NASH. Maintaining a healthy diet, exercising regularly, taking appropriate medication, and being vigilant about complications are essential for delaying the progression of NASH and DM. These are also the primary future directions of research.
    REGISTRATION NUMBER: Registration number: 1020973(PROSPERO).
    Keywords:  Nonalcoholic steatohepatitis; bibliometric analysis; citeSpace.; diabetes mellitus; hotspots
    DOI:  https://doi.org/10.2174/0118715303396313250904204350
  50. Discov Oncol. 2025 Sep 24. 16(1): 1694
       BACKGROUND: Hepatocellular carcinoma (HCC) poses a substantial global health burden with high morbidity and mortality rates. Radiomics, which extracts quantitative features from medical images to develop predictive models, has emerged as a promising non-invasive approach for HCC diagnosis and management. However, comprehensive analysis of research trends in this field remains limited.
    METHODS: We conducted a systematic bibliometric analysis of radiomics applications in HCC using literature from the Web of Science Core Collection (January 2006-April 2025). Publications were analyzed using CiteSpace, VOSviewer, R, and Python scripts to evaluate publication patterns, citation metrics, institutional contributions, keyword evolution, and collaboration networks.
    RESULTS: Among 906 included publications, we observed exponential growth, particularly accelerating after 2019. A global landscape analysis revealed China as the leader in publication volume, while the USA acted as the primary international collaboration hub. Countries like South Korea and the UK demonstrated higher average citation impact. Sun Yat-sen University was the most productive institution. Research themes evolved from fundamental texture analysis and CT/MRI applications toward predicting microvascular invasion, assessing treatment response (especially TACE), and prognostic modeling, driven recently by the deep integration of artificial intelligence (AI) and deep learning. Co-citation analysis revealed core knowledge clusters spanning radiomics methodology, clinical management, and landmark applications, demonstrating the field's interdisciplinary nature.
    CONCLUSION: Radiomics in HCC represents a rapidly expanding, AI-driven field characterized by extensive multidisciplinary collaboration. Future priorities should emphasize standardization, large-scale multicenter validation, enhanced international cooperation, and clinical translation to maximize radiomics' potential in precision HCC oncology.
    Keywords:  Artificial intelligence; Bibliometric analysis; Hepatocellular carcinoma; Radiomics; Research trends
    DOI:  https://doi.org/10.1007/s12672-025-03620-x
  51. J Glob Antimicrob Resist. 2025 Sep 20. pii: S2213-7165(25)00208-5. [Epub ahead of print]
       AIM: This study aimed to map the Southeast‑Asian research landscape on antimicrobial resistance (AMR) using bibliometric techniques.
    BACKGROUND: Despite AMR's growing threat and Southeast Asia's high-risk profile, no comprehensive bibliometric synthesis as examined AMR research trajectories in areas such as diagnostics, genomic surveillance, and policy frameworks, along with the region's evolving contributions.
    METHODS: A total of 1,989 Scopus-indexed articles (2014-2024; mean citations = 17.33 per document) were analyzed in VOSviewer (v 1.6.20). Bibliographic cleaning was performed in Microsoft Excel, and no additional mapping tools (e.g., CiteSpace, BibExcel) were used. Co-citation analysis identified influential publications and intellectual domains, while co-word analysis revealed thematic clusters and keyword co-occurrence patterns.
    RESULTS: Between 2014 and 2024, AMR publications in Southeast Asia grew steadily, peaking in 2024 with over 320 articles. The four co-citation clusters encompassed (1) global AMR governance and risk framing, (2) genomic tools for resistance detection, (3) foodborne AMR and standardized lab protocols, and (4) phylogenomic tracking of resistance evolution. The four co-word clusters revealed focus areas in diagnostic surveillance, sociodemographic patterns, One Health perspectives, and molecular epidemiology. Despite this growth (1,989 total articles), Southeast Asian research played a prominent role in zoonotic AMR surveillance and genomic studies but remained underrepresented in highly cited publications and globally influential policy discussions.
    CONCLUSIONS: The findings underscore the need for equitable integration of Southeast Asia into the global AMR agenda. Strengthening regional genomic surveillance, adapting global frameworks to local systems, and embedding AMR competencies in public health and nursing education are critical for advancing policy and capacity-building.
    Keywords:  Health systems strengthening; One Health; Southeast Asia; antimicrobial resistance; bibliometric analysis; drug resistance; genomic surveillance
    DOI:  https://doi.org/10.1016/j.jgar.2025.09.004
  52. Pathogens. 2025 Sep 16. pii: 938. [Epub ahead of print]14(9):
      Pathogenic enteric viruses are a leading cause of gastroenteritis-related mortality worldwide. However, the architecture of this research field remains poorly quantified. This bibliometric analysis provides a comprehensive overview of 35 years of global scientific output on major enteric viruses, such as rotavirus, norovirus, astrovirus, sapovirus, and non-polio enteroviruses, to map trends, methodological developments, and geographic disparities. We conducted a systematic search of PubMed and Scopus (1990-2024), identifying 10,017 records. After deduplication and eligibility screening, a final corpus of 8320 publications was analyzed using Bibliometrix (Biblioshiny 5.0) in R (version 4.3.0) and VOSviewer (Version 1.6.20). We found that scientific production grew steadily (CAGR = 5.84%), reaching its peak in 2021. The field is characterized by profound thematic and geographic disparity: rotavirus dominated the literature (56.3% of publications), followed by norovirus (30.8%), while other viruses were severely underrepresented (<9% each). Geographically, output was highly concentrated, with the top five countries (the USA, China, Japan, India, and Brazil) producing 92.4% of the publications. In contrast, high-burden regions, such as sub-Saharan Africa and Latin America, contributed only 7.6%. Genomic sequencing gained prominence, being cited in over 26.2% of publications from 2020 to 2024, reflecting a methodological shift accelerated by the application of wastewater-based epidemiology during the COVID-19 pandemic. In conclusion, while genomic tools and environmental monitoring are transforming enteric virus research, its progress is hampered by deep and persistent inequalities. These include a narrow focus on rotavirus and a significant disparity between regions with high disease burdens and those with high research outputs. Closing this gap requires targeted investments in equitable collaboration, local genomic capacity, and integrated public health interventions combining vaccination, WASH, and One Health strategies.
    Keywords:  bibliometric analysis; diagnostics; enteric viruses; epidemiology; one health; public health
    DOI:  https://doi.org/10.3390/pathogens14090938
  53. J Intell. 2025 Sep 19. pii: 123. [Epub ahead of print]13(9):
      This study presents a comprehensive bibliometric and thematic analysis of social and emotional learning (SEL) research in primary education, aiming to map its evolution, key contributors, and conceptual structure. Drawing on 915 peer-reviewed articles published between 1983 and 2025, retrieved from Web of Science and Scopus, the analysis employed performance metrics, science mapping, and thematic clustering techniques. Findings reveal a marked acceleration in SEL publications since the mid-2010s, with the United States, United Kingdom, and Australia leading both in research output and collaborative networks. Science mapping identified concentrated author and institutional clusters, while also highlighting geographic disparities in global research participation. Thematic analysis uncovered a shift from early focuses on behavioral and emotional regulation toward systemic, school-based interventions emphasizing mental health, resilience, professional development and family engagement. Clustering results positioned 'social-emotional learning' as the densest yet fragmented basic theme, reflecting its structural centrality alongside persistent conceptual dispersion across intervention models, implementation processes, and target populations. This study's findings offer a macro-level synthesis of the SEL research landscape in primary education with the related implications being discussed.
    Keywords:  bibliometric analysis; primary schools; research trends; social and emotional learning (SEL); thematic mapping
    DOI:  https://doi.org/10.3390/jintelligence13090123
  54. Med Sci (Basel). 2025 Sep 15. pii: 191. [Epub ahead of print]13(3):
       BACKGROUND: Cognitive and neuropsychological effects of cancer and its treatments have gained increasing attention over the past decade, with growing evidence of persistent deficits across multiple cancer types. While numerous studies have examined these effects, the literature remains fragmented, and no comprehensive bibliometric synthesis has been conducted to map the field's intellectual structure and emerging trends.
    METHODS: A bibliometric and science mapping analysis was performed using the Scopus database to identify peer-reviewed articles published between 2015 and 2025 on neuropsychological or cognitive outcomes in adult cancer populations. Data from 179 eligible publications were analyzed with VOSviewer and Microsoft Power BI, applying performance metrics and network mapping techniques, including co-authorship, bibliographic coupling, co-citation, and keyword co-occurrence analyses.
    RESULTS: Publication output increased steadily over the decade, with leading contributions from the Journal of Neuro-Oncology, Psycho-Oncology, and Brain Imaging and Behavior. Co-citation analysis identified three core intellectual pillars: (i) clinical characterization of cancer-related cognitive impairment, (ii) mechanistic and neuroimaging-based investigations, and (iii) neurosurgical and neuropathological research in brain tumors. Keyword mapping revealed emerging themes in sleep and circadian rhythm research, biological contributors to cognitive decline, and scalable rehabilitation strategies such as web-based cognitive training. Collaborative networks, while showing dense local clusters, remained moderately fragmented across disciplines.
    CONCLUSIONS: This review provides the first quantitative, decade-spanning map of cognitive oncology research, highlighting both consolidated knowledge areas and underexplored domains. Future efforts should prioritize methodological standardization, cross-disciplinary collaboration, and integration of cognitive endpoints into survivorship care, with the ultimate aim of improving functional outcomes and quality of life for cancer survivors.
    Keywords:  bibliometric analysis; cancer-related cognitive impairment; cognitive rehabilitation; neuropsychology; science mapping
    DOI:  https://doi.org/10.3390/medsci13030191
  55. Medicine (Baltimore). 2025 Sep 19. 104(38): e44741
       BACKGROUND: Although effective vaccines are available, herpes zoster (HZ) remains a considerable global health concern, particularly among the elderly. This study aimed to systematically map the research landscape and evolutionary trends in HZ vaccine development.
    METHODS: A comprehensive bibliometric analysis was conducted on 551 peer-reviewed publications from the Web of Science Core Collection database (retrieved before April 25, 2025). CiteSpace and VOSviewer were utilized to analyze research output, collaborations, and thematic evolution.
    RESULTS: The United States leads in research output and international collaboration, with Vaccine identified as the primary journal publishing HZ vaccine-related studies. Current research evaluates vaccine immunogenicity and efficacy across populations, elucidating protection mechanisms (with glycoprotein E as a key antigen), and addressing real-world challenges like vaccine hesitancy and strategy optimization for high-risk groups. The analysis indicates that recombinant subunit vaccines are currently the most established and widely recognized, with emerging mRNA and virus-like particle technologies.
    CONCLUSION: This analysis provides a holistic overview of HZ vaccine research, highlighting key trends and identifying critical gaps in long-term safety data and global vaccine equity. These findings are vital for informing future research and policy to enhance worldwide HZ prevention.
    Keywords:  CiteSpace; VOSviewer; bibliometric; herpes zoster; shingles; vaccine
    DOI:  https://doi.org/10.1097/MD.0000000000044741
  56. Pharmaceutics. 2025 Aug 25. pii: 1104. [Epub ahead of print]17(9):
      Background/Objectives: Nanoemulsions and microemulsions are promising drug delivery systems capable of enhancing the solubility, stability, and bioavailability of active pharmaceutical ingredients, particularly for central nervous system (CNS) disorders. This study presents a bibliometric analysis of scientific publications on intranasal nanoemulsions from 2004 to 2024, based on data from the Scopus database. Methods: A total of 379 articles were analyzed using Bibliometrix and VOSviewer to identify publication trends, leading countries and institutions, prominent journals, and keyword networks. Results: Publications grew significantly over the last decade, with India, the United States, and China leading in volume. Keyword analysis revealed strong thematic clusters related to "brain targeting," "drug delivery," and "intranasal administration," highlighting this route's potential for bypassing the blood-brain barrier. The most studied compounds included curcumin, quercetin, carbamazepine, diazepam, and insulin, each with therapeutic applications in neurodegenerative and psychiatric disorders. Conclusions: The findings highlight growing interest in intranasal nano- and microemulsions as a non-invasive and efficient CNS delivery strategy. Future research can bridge translational gaps, enhancing efficacy and safety while meeting regulatory expectations for patient-centered drug development. This study provides a comprehensive overview of current trends and serves as a guide for advancing innovative intranasal delivery platforms.
    Keywords:  Bibliometrix; intranasal; microemulsion; nanoemulsion; scientometry
    DOI:  https://doi.org/10.3390/pharmaceutics17091104
  57. Naunyn Schmiedebergs Arch Pharmacol. 2025 Sep 24.
      Integrity of academic publishing is increasingly undermined by fake publications massively produced by commercial "editing services" (so-called "paper mills"). These services use AI-supported production techniques at scale and sell fake publications to students, scientists, and physicians under pressure to advance their careers. Because the scale of fake publications in biomedicine is unknown, we developed an easy-to-apply rule to red-flag potentially fake publications and estimate their number. After analyzing questionnaires sent to authors of published papers, we developed simple classification rules and tested them in a 9-step bibliometric analysis in a sample of 17,120 publications listed in PubMed®. We first validated various simple rules and finally applied a multifactorial tallying rule comparing 400 known fakes with 400 random (presumed) non-fakes. This rule was then applied to 1,000 random publications each from 2020 and 2023. The multifactorial tallying rule was the best red-flagging method, with a 94% sensitivity and only a 11.5% false-alarm rate. The rate of red-flagged articles increased during the last decade, reaching an estimated 14.9% in 2020 and 16.3% in 2023. Countries with the highest proportion of read-flagged publications were China, India, Iran, Russia, and Turkey, with China and India the largest absolute contributors globally. Applying Bayes' rule resulted in an estimate of 5.8% actual fakes in the biomedical literature. Given 1.86 million Scimago-listed biomedical publications in 2023, we estimate the actual number of true fakes at 107.800 articles per year, growing steadily. Scientific publications in biomedicine can be red-flagged as potentially fake using fast-and-frugal classification rules to earmark them for subsequent scrutiny. When applying Bayes´rule, the annual true scale of fake publishing in biomedicine is about 19 times that of the 5.671 biomedicine retractions in 2023. This scale of fraudulent publishing is concerning as it can damage trust in science, endanger public health, and impact economic spending. But fake detection tools can enable retractions of fake publications at scale and help prevent further damage to the permanent scientific record.
    Keywords:  Biomedical science; Fake; Paper mill; Research integrity; Science fraud; Trust
    DOI:  https://doi.org/10.1007/s00210-025-04275-9
  58. Clin Exp Rheumatol. 2025 Sep 18.
       OBJECTIVES: Autoimmune diseases (ADs) are chronic inflammatory disorders characterised by systemic or organ-specific immune hyperactivation. Ultrasound (US), a radiation-free, cost-effective, and operator-friendly imaging modality, holds significant potential for clinical management of ADs. This study aims to map the global research landscape of US in ADs through bibliometric analysis.
    METHODS: English-language articles and reviews were retrieved from the Web of Science Core Collection. CiteSpace was used for cluster analysis and burst detection of research; VOSviewer generated co-occurrence networks; Biblioshiny R package visualised contributions by countries, institutions, authors, journals, citations, and keywords.
    RESULTS: A total of 1333 publications (2008-2024) were analysed. France emerged as the leading contributor in influence metrics, with Assistance Publique-Hôpitaux de Paris as the central collaborative hub. Key researchers included Craig Sable, Andrea Beaton, and Emmy Okello. Core journals were Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques and Clinical and Experimental Rheumatology. Current research priorities focus on rheumatic heart disease (RHD) and rheumatoid arthritis (RA), while glandular and intestinal ultrasonography show emerging potential.
    CONCLUSIONS: Over the past 16 years, US has demonstrated versatile roles in ADs, validating its clinical utility. Future priorities include reducing the disease burden of RHD and advancing precision medicine in RA through US-guided strategies.
    DOI:  https://doi.org/10.55563/clinexprheumatol/53qm54
  59. J Am Acad Orthop Surg. 2025 Sep 24.
       INTRODUCTION: Comparisons made between spine-trained neurosurgeons (Neuro) and orthopaedic surgeons (Ortho) can be a delicate matter. Considering most authors are spine surgeons, one may wonder if study results inappropriately favor authors' own specialties. The purpose of this study was to perform a bibliometric analysis of all studies comparing spine surgeons of each training pathway and to evaluate potential biases when reporting study results.
    METHODS: A systematic review was conducted according to the PRISMA statement. All literature comparing Neuro and Ortho before May 2022 were identified. Included articles were categorized according to the training backgrounds of the first and last authors ("Neuro-Neuro," "Ortho-Ortho," or "Author Diverse"), evaluated for inclusion of both Neuro and Ortho authors from the total author list, and classified by journal type of publication ("Neuro Journal," "Ortho Journal," or "Combined Journal"). A Neuro and Ortho spine surgeon each independently reviewed a subset of articles evaluating postoperative outcomes, categorizing the articles' stated conclusions (Pro-Neuro, Pro-Ortho, Neutral). Student t-test and Chi-squared analyses were used when appropriate to test for significance. Alpha level was set at <0.05.
    RESULTS: A total of 80 studies were identified. Overall, 26 Neuro-Neuro articles, 34 Ortho-Ortho articles, and 20 Author Diverse articles were included. Neuro-Neuro authors were found to publish more in Neuro Journals (P < 0.001). No differences were observed for inclusion of both Neuro and Ortho authors between studies published by the three different author types. Overall, there were 22 articles comparing postoperative outcomes: 15 articles (68%) reported no notable differences, whereas 3 (14%) found improved outcomes with Neuro, and 4 (18%) found improved outcomes with Ortho. No notable differences were found in outcomes when analyzed according to author type (P = 0.531), journal type (P = 0.962), and database used (P = 0.636).
    CONCLUSIONS: The growing body of literature comparing Neuro and Ortho spine surgeons shows little differences in surgical outcomes and no evidence of bias.
    LEVEL OF EVIDENCE: V.
    DOI:  https://doi.org/10.5435/JAAOS-D-23-00684
  60. J Strength Cond Res. 2025 Oct 01. 39(10): e1188-e1194
       ABSTRACT: Hunzinger, KJ, Pollen, TR, Bilimoria, AM, Hough, AK, Hough, JD, Lutz, VN, Medagam, RH, and Schneider, ALC. Representation of women authors in 4 decades of rugby research. J Strength Cond Res 39(10): e1188-e1194, 2025-Gender bias in scientific publication, particularly authorship, is common; however, its extent in rugby research remains unclear. This study examined the prevalence of authorship by gender among first, last, and corresponding authors of rugby research over 4 decades. Indexed rugby studies published through September 29, 2024, were collected from 3 databases (Web of Science, Embase, and PubMed). Articles were screened by 2 reviewers, with a third reviewer for consensus. Author gender was identified through names and regional data using the Genderize database. Percentages of women authors were calculated, and Fisher's exact tests compared first or corresponding author gender pairs. Logistic regression assessed trends over time by role, publication year, and author count. Of 10,142 articles screened, 2,258 (22.3%) were included. Women represented 20.0% of first authors, 16.0% of last authors, and 17.9% of corresponding authors. Publication frequency increased over time for both genders, but the gender ratio remained stable. The most common first/corresponding author pairing was man/man (71.6%), significantly higher than other author gender pairs (p < 0.001). Publication year was associated with increased odds of female first and corresponding authorship (both p-trend < 0.05), and more authors per paper was associated with increased odds of woman first author (OR = 1.04 [95% CI = 1.00-1.08]). Consistent with other fields, women authors are underrepresented in rugby research. These disparities may limit diverse perspectives in the field and hinder the visibility and career advancement of women researchers. Potential underlying factors driving these disparities should be investigated to inform policies that promote equitable access to funding, research opportunities, and leadership roles in rugby science.
    Keywords:  contact sports; disparities; minorities; publication; sex
    DOI:  https://doi.org/10.1519/JSC.0000000000005183
  61. BMJ Support Palliat Care. 2025 Sep 22. pii: spcare-2025-005441. [Epub ahead of print]
       BACKGROUND: The integration of palliative care for individuals with psychiatric disorders is critically important yet remains under-researched, highlighting substantial gaps in healthcare systems and access to integrated care.
    AIMS: This bibliometric analysis systematically examines the research landscape of palliative care for psychiatric disorders, identifying key themes, trends, influential sources and knowledge gaps to inform future research and policy.
    METHOD: A bibliometric analysis of 82 peer-reviewed publications (1985-2024) from the Web of Science Core Collection was conducted using Bibliometrix and VOSviewer, analysing publication trends, influential sources and countries, keyword patterns, thematic evolution and emerging research clusters.
    RESULTS: The analysis reveals a significant acceleration in research activity after 2017. Five distinct research clusters emerged, mapping the core intersections of the field: (1) Palliative Care in Dementia and Related Cognitive Disorders; (2) Addressing Psychological and Spiritual Needs at the End of Life; (3) The Interplay of Mental Health and Physical Illness in Palliative Settings; (4) Optimising Quality of Life in Terminal Cancer Care; and (5) Addressing Pain in Patients with Mild Cognitive Impairment. A substantial Western-centric research bias was also observed.
    CONCLUSIONS: This study provides the first bibliometric map of psychiatric palliative care, identifying key thematic intersections and research gaps. The findings highlight an urgent need for integrated care pathways, culturally sensitive methodologies and expanded global research. Addressing how social determinants of health impact access to quality palliative care for this vulnerable population is critical for achieving health equity.
    Keywords:  Depression; Palliative Care; Psychological care
    DOI:  https://doi.org/10.1136/spcare-2025-005441
  62. Front Oncol. 2025 ;15 1646064
      [This corrects the article DOI: 10.3389/fonc.2025.1562539.].
    Keywords:  CiteSpace; DNA damage repair; VOSviewer; bibliometric study; breast cancer; global trends
    DOI:  https://doi.org/10.3389/fonc.2025.1646064
  63. Front Med (Lausanne). 2025 ;12 1678005
      [This corrects the article DOI: 10.3389/fmed.2025.1610063.].
    Keywords:  antimicrobial resistance; bibliometric analysis; genomic surveillance; nanopore sequencing; pathogenic microorganisms; real-time
    DOI:  https://doi.org/10.3389/fmed.2025.1678005
  64. Front Med (Lausanne). 2025 ;12 1633371
       Background: The critically ill patient's journey can broadly be divided into three phases; events prior to admission, during the ICU stay, and following discharge. There is a paucity of evidence on what proportion of research outputs in high-impact intensive care journals address the respective phases. We aimed to investigate how intensive care research published in SCImago's top five journals mapped onto phases of care and the National Institute of Health and Care Research James Lind Alliance (NIHR JLA) Priority Setting Partnership research topics over a decade. The study was prospectively registered with the Open Science Framework https://osf.io/r8vs5/.
    Methods: We conducted a bibliometric cross-sectional analysis of intensive care research published in 2012 and 2022, in the top five intensive care journals according to the SCImago ranking system. We categorised studies according to phases of care: "pre-ICU", "in ICU", "post-ICU", or "multiple phases"; and according to the previously published NIHR JLA research topics. We adhered to relevant PRISMA and BIBLIO reporting guidelines in conducting the review.
    Results: In 2012 and 2022, respectively, 755 (73%) and 602 (73.7%) studies were focused on the "in ICU" phase, 148 (14.3%) and 87 (10.6%) studies on the "pre-ICU" phase, and 39 (3.8%) and 56 (6.9%) studies on the "post-ICU" phase. In both years, two NIHR JLA research topics were most represented: "respiratory/ventilation" (19.1% and 26.6% in 2012 and 2022, respectively) and "infection/sepsis" (15.6% and 13.7% in 2012 and 2022, respectively).
    Conclusion: Among the top five intensive care journals according to the SCImago ranking system, research tends to be centred on the period during patients' ICU stay, and characterised most by the topics of "respiratory/ventilation" and "infection/sepsis."
    Keywords:  NIHR James Lind Alliance; SCImago; bibliometric analysis; critical illness; emergency care; intensive care; post-intensive care syndrome
    DOI:  https://doi.org/10.3389/fmed.2025.1633371
  65. J Neurosurg. 2025 Sep 26. 1-7
       OBJECTIVE: Research output among neurosurgery residency applicants has increased in recent years. The authors sought to quantify the publication quantity of board-certified US neurosurgeons and to determine how publication quantity has changed over time.
    METHODS: Publication data were extracted from Scopus for all neurological surgeons listed as board certified since 1980 by the American Board of Neurological Surgery. Distributions were analyzed on a decade-to-decade as well as continuous basis. Pre-board certification quantity of publication (general and first/senior author) was analyzed using multivariable regression. Univariate regression of pre-board certification rates was used to predict post-board certification rates.
    RESULTS: For each decade since 1980, neurosurgeons have published more before receiving board certification than the decade prior, both in total as well as first/senior author publications. Neurosurgeons have also been publishing earlier as well as with increased coauthor counts (p < 0.001). A more recent date of board certification remains a significant and independent predictor of publication count when corrected for time since first publication and average coauthor counts (p < 0.001). Finally, the pre-board certification publication rate is an independent and significant predictor for the post-board certification publication rate (p < 0.001).
    CONCLUSIONS: This study suggests that neurosurgeons have consistently published earlier in their careers and in increasingly higher quantities over time. This finding is in line with similar trends for neurosurgery applicants, showcasing increasing output across career stages, which has important impacts on the field.
    Keywords:  bibliometrics; early-career research output; history; neurosurgical education; publication arms race
    DOI:  https://doi.org/10.3171/2025.5.JNS25565
  66. J Womens Health (Larchmt). 2025 Sep 22.
      Understanding the public health impact of women's health research is crucial for improving health outcomes and guiding future research priorities. Bibliometric analysis offers a unique suite of tools to identify opportunities to increase impact and measure the dissemination of women's health research. Using 2018-2021 mortality data from the National Vital Statistics System, we utilized age-adjusted death rates to identify conditions with the highest relative mortality risk for females versus males. Our analysis showed that breast cancer, Alzheimer's disease, infections of the kidney, and acute rheumatic fever and chronic rheumatic heart diseases were associated with the highest relative mortality risk for females. Using a systematic keyword search strategy, we identified 219 Centers for Disease Control and Prevention (CDC)-authored publications published between 2018 and 2023 featuring these conditions in a database of CDC-authored publications. For relevant publications on each condition, we evaluated five bibliometric indicators measuring media attention, academic citations, and policy citations. Overall, CDC's publications on these conditions did not demonstrate a gap in media attention, academic citations, and policy citations compared with other agency publications, underscoring the agency's effectiveness in disseminating its research on these topics. Assessing bibliometric indicators for published research on conditions with disproportionate relative mortality risk for females can reveal potential gaps in research coverage, highlight research successes, and inform strategic decisions for disseminating women's health research.
    Keywords:  Centers for Disease Control and Prevention; National Center for Health Statistics; National Vital Statistics System; bibliometrics; mortality; women’s health research
    DOI:  https://doi.org/10.1177/15409996251379401
  67. Pharmaceutics. 2025 Aug 29. pii: 1131. [Epub ahead of print]17(9):
      The complex pathological mechanisms of atherosclerosis (AS) involve lipid metabolism disorders, inflammatory responses, and plaque instability, resulting in significant challenges to effective clinical management. Current therapeutic approaches, such as statins and stent implantation, suffer from issues including single-target action, notable side effects, and the risk of restenosis. Nanoparticle-based drug delivery systems have demonstrated considerable promise by enabling the codelivery of multiple agents directly to atherosclerotic lesions, thereby improving therapeutic efficacy and minimizing systemic toxicity. Among various nanomaterials, organic nanoparticles have recently emerged as a research hotspot in the field of AS treatment due to their excellent biocompatibility, degradability, and potential for targeted modification. This review systematically summarizes the recent advances and emerging trends in the application of organic nanoparticles for AS treatment, employing bibliometric analysis to delineate research frontiers. We employed bibliometric tools to analyze 1999 articles on organic nanocarriers for AS therapy indexed in the Web of Science Core Collection. The analysis included co-occurrence and clustering techniques to explore influential keywords and key contributors. Temporal analysis was applied to identify emerging research hotspots and track the evolution of this field. The literature reveals three major current focal areas: (1) the development of engineered biomimetic organic nanoparticles; (2) the design of multifunctional polymer-based organic nanocarriers; and (3) the innovation of organic-coated stents. This article not only provides a comprehensive overview of cutting-edge organic nanotechnologies for AS therapy, but also critically discusses the challenges in clinical translation, offering insights into future directions for the development of safe, effective, and personalized nanomedicine strategies against AS.
    Keywords:  atherosclerosis; bibliometric analysis; drug delivery; nanotechnology; organic nanoparticles
    DOI:  https://doi.org/10.3390/pharmaceutics17091131
  68. Healthcare (Basel). 2025 Sep 13. pii: 2293. [Epub ahead of print]13(18):
      Introduction: The objective of the present study was to systematically explore the scientific literature to examine the relationship between respiratory diseases and economic cost. The research question focused on identifying the thematic, methodological, and temporal trends that link these two scientific fields. Methods: A comprehensive search was conducted in the PubMed database using the terms "Pulmonology OR respiratory" AND "Cost", which returned 30,274 publications from 1921 up to April 2025. For the bibliometric review, VOSviewer software was used to create bibliometric maps through the tools of network, overlay, and density visualization. Results: The analysis revealed six clusters, which include clinical prognosis, pandemics, pharmacoeconomics, epidemiology, chronic conditions, and health services research. After 2010, there was a particularly important increase in academic research related to pulmonology and cost, with this rise being especially evident during and after the COVID-19 pandemic. Recent studies have increasingly focused on cost-effectiveness, quality of life, hospitalization, and multimorbidity. Discussion: The scientific field of respiratory conditions is undergoing a substantial transformation, shifting from traditional clinical descriptions to an interdisciplinary framework that incorporates economic evaluation. This evolution highlights the need for strategies based on economically informed decisions and effective public health policy making. The term "economic cost" in this study refers to both direct costs (e.g., hospitalization and treatment) and indirect economic impacts, such as resource allocation and healthcare burden. Conclusions: The findings demonstrate that research linking respiratory diseases and economic cost is expanding rapidly, particularly after the COVID-19 pandemic, and is characterized by interdisciplinary approaches that combine clinical, epidemiological, and economic perspectives. This trend underlines the importance of integrating cost-effectiveness considerations into respiratory healthcare policies and highlights the need for collaborative strategies to ensure sustainable and efficient health systems.
    Keywords:  PubMed; VOSviewer; bibliometric review; cost; health economics; pulmonology; respiratory diseases; respiratory medicine
    DOI:  https://doi.org/10.3390/healthcare13182293
  69. PeerJ Comput Sci. 2025 ;11 e3048
      Identifying the core sub-teams that drive productivity in scientific collaboration networks is essential for research evaluation and team management. However, existing methods typically rank individual researchers by bibliometric impact or select structurally cohesive clusters, but rarely account for both collaboration patterns and joint scientific output. To address this limitation, we propose a novel two-dimensional framework that integrates network topology with research performance to identify core sub-teams. Specifically, we measure each sub-team's marginal structural contribution using the Shapley value and quantify its collective impact using a sub-team H-index. To efficiently identify high-contributing sub-teams, we employ the Monte Carlo Tree Search algorithm, along with an approximation strategy to estimate Shapley values under computational constraints. We evaluate our method on 61 real-world scientific collaboration teams from Web of Science and Baidu Scholar data. Experimental results validate the effectiveness of our method in identifying core sub-teams, with the highest collaborative and citation impact. The proposed method offers a valuable analytical tool for research managers and funding agencies seeking to locate high-impact collaborative clusters, and it provides a generalizable framework for studies requiring the integration of structural and performance-based indicators in network analysis.
    Keywords:  Core sub-team; MCTS; Scientific collaboration networks; Shapley value analysis
    DOI:  https://doi.org/10.7717/peerj-cs.3048
  70. J Multidiscip Healthc. 2025 ;18 5917-5933
       Purpose: Alzheimer's disease (AD) is a growing global health burden, yet effective therapies remain elusive. Microglia-the brain's resident immune cells-have emerged as key players in AD, capable of both neuroprotection and neurotoxicity. To elucidate research progress and gaps, we conducted a bibliometric analysis of global studies on "microglia and AD" from 2010 to 2025, highlighting advances beyond prior reviews.
    Methods: We searched the Web of Science Core Collection for relevant publications (2010-2025). After screening and deduplication, 12,275 records were analysed with CiteSpace 6.2.R4 to generate co-citation networks, keyword clusters, citation-burst timelines, and collaboration maps at national, institutional, and author levels.
    Results: Annual output rose markedly, peaking in 2022. The United States and China led the field; Harvard University, the University of California System, and the Chinese Academy of Sciences were the most prolific institutions. Influential authors included Holtzman, Heneka, Zetterberg, and Colonna. Co-citation analysis revealed three dominant knowledge clusters: microglial activation, TREM2-mediated immune responses, and neuroinflammation. Keyword evolution showed growing attention to TREM2 variants, NLRP3 inflammasome, single-cell omics, and novel imaging techniques, reflecting a shift toward microglial heterogeneity and translational research.
    Conclusion: Microglia occupy a central position in AD pathogenesis through intertwined molecular pathways and dynamic functional states. Future work should refine subtype-specific roles, integrate peripheral-central immune interactions, and accelerate the translation of mechanistic insights into targeted interventions. This bibliometric overview maps collaboration patterns and emerging themes, providing a strategic guide for researchers aiming to advance microglia-focused AD therapeutics.
    Keywords:  Alzheimer’s disease; CiteSpace; bibliometric analysis; collaboration network; microglia; neuroinflammation
    DOI:  https://doi.org/10.2147/JMDH.S521350
  71. Dermatol Online J. 2025 Jun 15. 31(3):
      Statistical mistakes can undermine research credibility. Identifying common errors may help researchers avoid them in future studies. This study evaluated the frequency and types of statistical mistakes in dermatology journal articles and identified article characteristics that predict these errors. A cross-sectional analysis was conducted on articles published in the 2023 volumes of 8 dermatology journals. Articles were screened for statistical tests, with a target sample of 200 selected pseudorandomly. Multivariable logistic regressions assessed predictors of statistical mistakes, including journal impact factor, statistician involvement, funding source, first author highest degree, and statistical package. Of the 189 articles analyzed, 78% contained at least one statistical mistake. Reporting mistakes were found in 67% and test selection errors in 46%. The absence of statistician involvement (aOR 2.49, P=0.03) and low journal impact factor (aOR 3.82, P=0.02) predicted the presence of at least one mistake. This sample from 8 journals is not representative of all dermatology literature. Original data were not available for testing of test assumptions, so appropriate test selection was determined using statistical conventions. Statistical mistakes are prevalent in dermatology literature. Researchers should review statistical best practices and consider involving a statistician in their work.
    DOI:  https://doi.org/10.5070/D331365357
  72. Ann Surg Open. 2025 Sep;6(3): e594
       Objectives: The study aims to investigate the landscape and trends in the use of Bayesian statistics in surgical papers published in high-impact journals over the past 2 decades, determine the characteristics of these papers, and assess the quality of Bayesian analysis reporting.
    Background: Observational and clinical trials have traditionally employed frequentist approaches. Bayesian framework enables the incorporation of prior evidence, flexible modeling of uncertainty, and returns a direct probabilistic summary of the estimates of interest that can provide valuable insight. However, their use in high-impact surgical research remains underexplored.
    Methods: Surgical articles from high-impact surgical and medical journals indexed in Web of Science and PubMed were retrieved for the period from January 2000 to August 2024. Data extraction covered bibliometrics and content details. The Reporting of Bayes Used in Clinical Studies scale (ROBUST) was used to assess Bayesian reporting quality.
    Results: A total of 120 articles were analyzed. The use of Bayesian statistics in surgical research has increased over time (compounded annual growth rate: 12.3%). General surgery (N = 39, 32.5%) and cardiothoracic surgery (N = 20, 16.7%) were the most represented specialties. The most common study designs were retrospective cohort studies (N = 50, 41.7%), meta-analyses (N = 38, 31.7%), and randomized trials (N = 19, 15.8%). Regression-based methods were the most frequently used (N = 51, 42.5%). The average ROBUST score was 4.1 ± 1.6 out of 7, with 54.0% (N = 54) of studies specifying priors and 29.0% (N = 29) justifying them.
    Conclusions: Bayesian statistics is increasingly incorporated into surgical research, predominantly observational studies and meta-analyses. However, improvements in the quality and standardization of Bayesian reporting are needed to enhance transparency and reproducibility.
    Keywords:  bayesian statistics; bibliometric analysis; surgery
    DOI:  https://doi.org/10.1097/AS9.0000000000000594
  73. O G Open. 2025 Oct;2(5): e113
       OBJECTIVE: We aimed to evaluate the conversion rate of conference abstract presentation to full manuscript among obstetrics and gynecology subspecialty society meetings.
    METHODS: We conducted a retrospective cohort study of 2019 meeting supplements from four subspecialty societies: 1) the American Society for Reproductive Medicine (ASRM), 2) the American Urogynecologic Society (AUGS), 3) the Society of Gynecologic Oncology (SGO), and 4) the Society for Maternal-Fetal Medicine (SMFM). All abstracts that were not subsequently withdrawn were included and queried on PubMed using a multimodal method that incorporated abstract keywords and the names of the first and last author to determine publication status. An abstract was classified as a published manuscript if the first author of the meeting abstract was credited in the final publication. The primary outcome was overall publication status. Secondary outcomes included subdivided oral and poster abstract publication conversion, publication journal type, manuscript journal impact factor, time to publication, and additional presentation metrics.
    RESULTS: Among the 3,425 total conference abstracts presented in 2019, the overall oral and poster abstract publication rate for all societies combined was 39.7% (subspecialty range, 33.1-47.5%). For only oral abstracts, 61.0% (subspecialty range, 50.7-78.6%) were published and, for only poster abstracts, 35.4% (subspecialty range 27.1-45.4%) were published. When comparing among subspecialty societies, there were significant differences in rates of oral abstract conversion, with ASRM at 50.7%, AUGS at 64.9%, SGO at 78.6%, and SMFM at 74.5% (P<.01), and in rates of poster abstract conversion, with ASRM at 27.1%, AUGS at 27.3%, SGO at 45.4%, and SMFM at 40.5% (P<.01). Most of the dissemination occurred in general obstetrics and gynecology journals and not in the society associated journals. The median (interquartile range) journal impact factor was 4.7 (2.1, 7.2) among oral abstracts and 3.3 (2.1, 4.8) among poster abstracts (P<.01). The median (interquartile range) time to publication was 16 months (9, 26 months) among oral abstracts and 17 months (9, 30 months) among poster abstracts (P=.13).
    CONCLUSION: Our contemporary evaluation of women's health research dissemination shows that a significant portion of research presented at obstetrics and gynecology subspecialty conferences remains unpublished, even after 5 years.
    DOI:  https://doi.org/10.1097/og9.0000000000000113
  74. Hereditas. 2025 Sep 26. 162(1): 187
      
    Keywords:  Bibliometrics; Cancer; Colorectal cancer; Palliative care; Tumor therapy
    DOI:  https://doi.org/10.1186/s41065-025-00559-5
  75. Front Psychol. 2025 ;16 1663529
      
    Keywords:  authorship; citation behavior; illusion of control; indirect citation; intentional stance
    DOI:  https://doi.org/10.3389/fpsyg.2025.1663529