bims-evares Biomed News
on Evaluation of research
Issue of 2025–09–14
seventeen papers selected by
Thomas Krichel, Open Library Society
  1. Global Trends and Collaborative Networks in Crush Syndrome: A Bibliometric Analysis From 2000 to 2025.
  2. Gait in depression: a bibliometric analysis and knowledge mapping of research trends over the past 20 years.
  3. Mapping the neuropathic pain biomarker landscape (2004-2024): A bibliometric analysis of thematic evolution, research silos, and the translational gap.
  4. A Bibliometric Analysis of Chinese Medicine for Allergic Rhinitis.
  5. Global Research Trends on Nanoplastics in Food: A Bibliometric Analysis of Human Health Concerns.
  6. [Analysis of the current research status and trends in retinal vein occlusion based on bibliometrics].
  7. Global Research Trends in Vertebral Artery Stenosis Treatment from 1980 to 2024: A Bibliometric and Visualized Analysis.
  8. Bibliometric and Visualized Analysis of the Therapeutic Application of Suprachoroidal Space From 2000 to 2024.
  9. Economic Assessment of Bio-oil Production from Algae: A Bibliometric Analysis.
  10. Scopus-based bibliometric analysis of research trends in silage feed and its impact on rumen fermentation in ruminants.
  11. Visual Mapping of Global Studies on Dental Hygienists: Trends and Emerging Hotspots.
  12. Research hotspots and emerging trends of artificial intelligence in the clinical management of mild cognitive impairment: A bibliometric and evidence-based analysis.
  13. From Pioneer to Participant: Bibliometric Evidence of Plastic Surgery's Changing Role in Orbital Fracture Research.
  14. EVOLVING TRENDS AND EMERGING THEMES IN GUT MICROBIOTA RESEARCH: A COMPREHENSIVE BIBLIOMETRIC ANALYSIS (2015-2024).
  15. Inaccuracies in Orthopaedic Research Fellowship Applications: A Study on Authorship Misrepresentations.
  16. Mapping leadership and communities in EU-funded research through network analysis.
  17. Trans-Atlantic analysis of gender representation in general thoracic surgery: Challenges permeate the academic community.
  1. J Multidiscip Healthc. 2025 ;18 5489-5503
    Global Trends and Collaborative Networks in Crush Syndrome: A Bibliometric Analysis From 2000 to 2025.
    Fan Song, Ding Long, Xiaoling Wu.
       Background: Crush syndrome (CS) is a severe, potentially fatal condition resulting from prolonged muscle compression, most commonly observed following disasters such as earthquakes and large-scale traumatic events. Despite its clinical significance, there has been a lack of comprehensive bibliometric analysis exploring global research trends, collaboration networks, and emerging topics in CS research.
    Methods: A comprehensive literature search was conducted in the Web of Science Core Collection to identify publications on CS from 2000 to 2025. Bibliometric analysis was performed using VOSviewer, CiteSpace, and the R package "Bibliometrix" to visualize co-authorship networks, institutional collaborations, and keyword co-occurrence patterns. Only English-language articles were included. Data were analyzed for publication trends, country and institutional contributions, leading authors and journals, and evolving research themes.
    Results: A total of 745 publications were included, demonstrating a consistent annual increase in research output. The United States, China, and Turkey were the most productive countries. Ghent University and Istanbul University were the leading institutions. Sever MS was identified as a major contributor to the field. Injury-International Journal of the Care of the Injured emerged as the most contributed journal. The most frequent research topics were acute kidney injury, disaster-related management, and pediatric aspects. Keyword and citation burst analysis revealed a historical focus on disaster epidemiology, with recent trends shifting toward clinical complications such as acute compartment syndrome and nerve-related conditions, as well as mechanistic studies including ferroptosis.
    Conclusion: This bibliometric analysis provides a comprehensive overview of global CS research, highlighting evolving hotspots, emerging themes, and key contributors. These findings may inform future research directions and support improved clinical management of CS.
    Keywords:  bibliometric analysis; collaborative networks; crush syndrome; intensive care unit; trauma medicine
    DOI:  https://doi.org/10.2147/JMDH.S527923
  2. Front Psychiatry. 2025 ;16 1457176
    Gait in depression: a bibliometric analysis and knowledge mapping of research trends over the past 20 years.
    Shao-Kui Kan, Nuan-Nuan Chen, Bo Peng, Ying-Li Zhang.
       Background: Depression carries a high risk of suicide, with many individuals failing to receive treatment due to diagnostic challenges and stigma. Gait is linked to depression, underscoring the importance of gait analysis in the diagnosis and treatment of depression. However, comprehensive and objective evaluations of the current research on gait in depression are lacking. This study aims to use bibliometric analysis and knowledge mapping to clarify research trends and status.
    Objective: This study employs bibliometric analysis to investigate gait in depression, summarizing historical and current trends while predicting future directions. This analysis will aid researchers and policymakers in understanding evolving trends and prioritizing research resources effectively.
    Methods: We conducted a computer-based search of the Web of Science core collection to identify articles and reviews related to depression and gait. Bibliometric analysis, involving the analysis of aspects such as countries or regions, institutions, authors, journals, keywords, and references, was performed using Excel 365, CiteSpace, and VOSViewer.
    Results: The analysis included a total of 848 publications from 2005 to 2024. The results showed a phased increase in publications, peaking in 2020 with 102 publications, followed by a gradual decline. Citations in this field showed a yearly increase, peaking in 2022 with 3920 citations before subsequently declining. The United States was identified as the most productive and influential country in this field, with the highest number of publications and citations. They have the institutions with the highest publications and citations. Leading authors in this field include Verghese Joe, Shimada Hiroyuki; and Rochester Lynn. Key journals include BMC Geriatrics, Journals of Gerontology Series and Medical Sciences, and Journal of the American Geriatrics Society. Frequently mentioned keywords in this field are depression, gait, gait speed, older adults, and dementia. Identification of distinctive gait patterns in depression, gait characteristics in the elderly, association between gait and cognitive decline, and interventions for abnormal gait constitute current research forefronts in this domain.
    Conclusions: This study is the first to utilize bibliometrics to visualize research in the field of gait-related depression. It reveals research trends and frontiers, providing valuable references for scholars seeking important research topics and potential collaborators.
    Keywords:  CiteSpace; VOSviewer; bibliometric; depression; gait; visual analysis
    DOI:  https://doi.org/10.3389/fpsyt.2025.1457176
  3. Medicine (Baltimore). 2025 Sep 05. 104(36): e44265
    Mapping the neuropathic pain biomarker landscape (2004-2024): A bibliometric analysis of thematic evolution, research silos, and the translational gap.
    Zihao Zhang, Qingpei Hao, Gaoquan Lv, Shijun Peng, Tao Wang, Xin Chang, Yuepeng Wang, Jia Ouyang, Ruen Liu.
       BACKGROUND: Despite a surge in neuropathic pain (NP) biomarker research over the past 2 decades, the translation of discoveries into clinical practice remains slow. To understand this translational gap, we conducted a comprehensive bibliometric analysis to map the field's evolution, intellectual structure, and strategic challenges.
    METHODS: We conducted a bibliometric analysis of NP biomarker-related publications from 2004 to 2024 using the Web of Science Core Collection (WoSCC) database. Tools including CiteSpace, VOSviewer and Scimago Graphica were employed to evaluate authors, institutions, countries/regions, journals, keywords and co-citations.
    RESULTS: A total of 2437 articles were included in this study. The United States and European countries play a leading role, while China demonstrates high publication output but comparatively lower citation impact. Keyword analysis identified 5 major research clusters, exposing a clear thematic evolution from foundational "molecular mechanisms" towards technology-driven frontiers, including "neuroimaging" and emerging biomarkers like "neurofilament light chain" (NfL).
    CONCLUSION: This study provides a strategic map of the NP biomarker field, highlighting a persistent gap between robust basic science discovery and its clinical application. The field's fragmentation into distinct research "silos" (e.g., molecular, neuroimaging) underscores that the primary future challenge is enhancing interdisciplinary integration. Accelerating progress will depend on building bridges between these domains to develop the multi-modal biomarker strategies essential for improving patient care.
    Keywords:  bibliometric analysis; biomarker; neurofilament light chain; neuroimaging; neuropathic pain; translational gap
    DOI:  https://doi.org/10.1097/MD.0000000000044265
  4. J Multidiscip Healthc. 2025 ;18 5603-5620
    A Bibliometric Analysis of Chinese Medicine for Allergic Rhinitis.
    Zheng-Fan Wang, Jun Xiong, Yong-Qi Du, Shuang Yang, Hai-Yan Xu.
       Purpose: This study aims to assess the current research status of Chinese medicine research on treating allergic rhinitis (AR) using bibliometric methods, and to explore research hotspots and pinpoint future trends in this field.
    Methods: Articles concerning Chinese medicine for AR in Web of Science Core Collection databases were searched from January 1, 2004, to May 31, 2024. VOSviewer 1.6.20 and CiteSpace 6.3.R1 software were used to conduct descriptive analysis, including publications, authors, countries, institutions, journals, cited journals, cited authors, cited references, and keywords from various angles.
    Results: A total of 221 publications were included. Paper production has increased over the past 20 years, despite fluctuations. The most productive country is China, whose Chengdu University of Traditional Chinese Medicine is the institution with the highest number of papers. Germany's Brinkhaus, Benno has the most papers in the discipline, while Bousquet J is the most influential author. Medicine is a journal that has the most research on Chinese medicine for treating AR, while Allergy has the most citations. The most frequently cited reference is a guideline concerning the diagnosis and treatment of AR. The most common keywords are allergic rhinitis, asthma, effect, prevalence, and Chinese herbal medicine.
    Conclusion: This study assessed the research status of Chinese medicine for AR via bibliometric approaches from 2004 to 2024, which may be useful for researchers to identify hotspots and frontier trends in this field.
    Keywords:  Chinese medicine; CiteSpace; VOSviewer; allergic rhinitis; bibliometrics
    DOI:  https://doi.org/10.2147/JMDH.S549146
  5. Foods. 2025 Sep 04. pii: 3102. [Epub ahead of print]14(17):
    Global Research Trends on Nanoplastics in Food: A Bibliometric Analysis of Human Health Concerns.
    Suriyakala Gunasekaran, Sathiyaraj Sivaji, Kayeen Vadakkan, San Yoon Nwe, Sanith Sri Jayashan, Suchada Sukrong.
      The increasing prevalence of nanoplastics (NPs) in food and their potential implications for human health have become a growing concern in scientific and public health discourse. Using the Scopus database, this bibliometric analysis provides a comprehensive overview of global research trends on NPs in food from 2015 to 2024. Results show a significant increase in publications and citations post-2019. China is the top-ranked country in terms of the number of publications, citations, collaborations, affiliations, and funding sponsors. The most impactful documents were review articles, indicating that this research field is currently in a synthesis stage. The most productive source was Science of the Total Environment, with 21 articles, while 9 of the top 10 most productive journals were published by Elsevier, highlighting the field's concentration in high-impact outlets. The most prolific authors were Wang, J., and Li, Y; Li, Y. was also the author with the most citation influence, with a h-index of 9. Keyword co-occurrence analysis showed seven thematic clusters formed from 50 individual keywords; the dominant terms were microplastics, NPs, and human health. These findings illustrate an evolving and interdisciplinary research field centered on evaluating the risks and detection of NPs in food and their implications for public health.
    Keywords:  VOSviewer; bibliometric analysis; food; human health; nanoplastics
    DOI:  https://doi.org/10.3390/foods14173102
  6. Zhonghua Yan Ke Za Zhi. 2025 Sep 11. 61(9): 706-714
    [Analysis of the current research status and trends in retinal vein occlusion based on bibliometrics].
    Y Y Su, Z Q Hu, W Q Weng, Y H Gu, Y B Feng, B B Cheng, N H Jiang.
      Objective: To assess the current research status of retinal vein occlusion (RVO) and to explore its research trends and hotspots based on bibliometrics. Methods: A bibliometric study was conducted on April 25, 2024, retrieving articles from China National Knowledge Infrastructure (CNKI), Wanfang, and Web of Science Core Collection covering 2014 to 2023. CiteSpace, VOSviewer, and Microsoft Excel were used for visualization and analysis of annual publications, country distribution, author productivity, journals, cited references, and keywords. Results: A total of 1 929 articles in Chinese and 2 764 international publications were identified. The ophthalmology journals dominated the publication venues. Retina-The Journal of Retinal and Vitreous Diseases published the highest number of foreign-language articles (n=178), accounting for 6.44% of the international literature analyzed. International Eye Science published the highest number of Chinese-language articles (n=140), accounting for 7.26% of the Chinese literature analyzed. Research on RVO followed an interdisciplinary development pattern, with research hotspots primarily focused on ophthalmology, molecular biology, and immunology. The U.S. produced the largest volume of papers (659), followed by China (481), while France achieved the highest citation impact (average 28.19 citations per article). Akitaka Tsujikawa was the most prolific foreign author (41 papers, 479 citations, average 10.89 citations per paper). The keyword analysis extracted 373 and 823 keywords from the Chinese and foreign literature, respectively, with major bursts in 2015 and 2020. The early studies focused on clinical and pathological features; recent research emphasized molecular mechanisms, novel drugs, and therapies. The keyword clustering identified 17 and 6 significant clusters in the Chinese and foreign literature, respectively. The topics such as macular edema, ranibizumab, vascular endothelial growth factor, and quality of life emerged in 2015 and remained as central priorities. Conclusion: RVO and macular edema are primary research foci both domestically and internationally. Macular edema, ranibizumab, vascular endothelial growth factor, and quality of life have become enduring hotspots within the field of RVO research over the past decade.
    DOI:  https://doi.org/10.3760/cma.j.cn112142-20241103-00492
  7. World Neurosurg. 2025 Sep 05. pii: S1878-8750(25)00796-X. [Epub ahead of print] 124440
    Global Research Trends in Vertebral Artery Stenosis Treatment from 1980 to 2024: A Bibliometric and Visualized Analysis.
    Fei-Yi Yan, Yi-Bing Sun, Yu Lu.
       OBJECTIVE: The present study intends to conduct a comprehensive bibliometric analysis of the research pertaining to the treatment of vertebral artery stenosis, with the objective of elucidating the evolution and trends in therapeutic strategies.
    METHODS: A bibliometric analysis of publications spanning between January 1, 1980, and August 13, 2024, was conducted utilizing the Web of Science Core Collection database. The analysis and visualization of the data were performed using VOSviewer, CiteSpace, and R package "bibliometrix" software.
    RESULTS: The analysis included 856 documents published in 261 journals. The United States (202 publications, 23.60%), China (195 publications, 22.78%), and Japan (119 publications, 13.90%) were the leading countries in research output, with Capital Medical University identified as the most productive institution (63 publications). Neurosurgery and Stroke emerged as the most influential journals, exhibiting the highest H-index (both H-index=8). Keyword clustering analysis revealed four distinct research domains: clinical trials and medical management; surgical interventions; endovascular techniques; and diagnostic approaches. The analysis revealed evolving research priorities in VAS treatment, highlighting "stents", "angioplasty" and "drug-coated balloon" as central themes. Keywords demonstrated a temporal evolution, with recent trends emphasizing "diagnosis", "ischemic stroke" and "endovascular treatment".
    CONCLUSIONS: The bibliometric analysis traces VAS treatment from surgical to advanced endovascular methods. Keyword clustering revealed four primary domains; burst analysis shows growing interest in drug-coated balloons and precision diagnostics. Future work should target novel endovascular devices, precise diagnostic criteria, and long-term outcomes. Clinically, emphasis is on minimally invasive interventions and integrating advanced imaging with personalized treatment strategies.
    Keywords:  Angioplasty; Bibliometrics; Constriction; Pathologic; Stents; Vertebral Artery
    DOI:  https://doi.org/10.1016/j.wneu.2025.124440
  8. Int J Surg. 2025 Sep 08.
    Bibliometric and Visualized Analysis of the Therapeutic Application of Suprachoroidal Space From 2000 to 2024.
    Kehan Jin, Lihui Meng, Jingyuan Yang, Chan Zhao, Youxin Chen.
       OBJECTIVES: To provide a bibliometric overview of the global research on the therapeutic applications of the suprachoroidal space (SCS) from 2000 to 2024.
    METHODS: Publications were retrieved from the Web of Science Core Collection using a defined search strategy. A total of 776 articles were analyzed for trends in publication volume, countries, institutions, authorship, journals, citations, and keywords. An analysis of top 10% highly cited publications was also conducted. Co-authorship, co-occurrence, and citation burst analyses were conducted using VOSviewer, bibliometrix (R), and CiteSpace.
    RESULTS: Global publications on SCS therapy increased steadily, with a 575% growth. The United States led in output (n = 274, 35.3%) and international collaboration. Top institutions included the University of Melbourne, Bionics Institute, and Osaka University. Fujikado Takashi was the most prolific author (34 publications), while Prausnitz Mark R R had the highest citation impact (50 per article). Investigative Ophthalmology & Visual Science was the most active journal (n = 50; 2249 citations). Keyword analysis revealed three main clusters: (1) drug delivery, (2) glaucoma treatment, and (3) retinal prosthesis. Overlay map indicated that research foci have shift from implantation to injection, minimally invasive approach, and clinical trials. Burst keywords showed suprachoroidal drug delivery (including gene therapy, ranibizumab, and triamcinolone acetonide) was a rapidly evolving and promising field for innovation, which was confirmed by analysis of high-impact publications.
    CONCLUSIONS: This study maps the global research landscape and emerging trends on the therapeutic applications of the SCS, underscores its translational nature, and fosters interdisciplinary collaboration in this evolving field.
    Keywords:  bibliometrics; drug delivery; microneedles; minimally invasive glaucoma surgery; retinal prosthesis; suprachoroidal space
    DOI:  https://doi.org/10.1097/JS9.0000000000003384
  9. Recent Pat Biotechnol. 2025 Aug 19.
    Economic Assessment of Bio-oil Production from Algae: A Bibliometric Analysis.
    Radhika Jaithaliya, Divya Jain, Dipjyoti Chakraborty, Kakoli Dutt.
       INTRODUCTION: The production of bio-oil from microalgae is gaining attention as an alternative renewable energy source. To generate advances in this field, it is essential to identify the gaps in existing research. Overcoming this barrier necessitates addressing methodologies that can assess the existing work and develop relationships between publications, research groups, and their impact.
    METHODS: To chart a course toward practicality, this study employs bibliometric indicators, leveraging tools such as R Studio, VOSviewer 1.6.19, and Biblioshiny for network visualization and analysis. Drawing on the Scopus database spanning 2004-2024, a meticulous keyword strategy effectively segregated relevant papers.
    RESULTS: The findings suggest that the total number of published documents is 1005. The publication trend on this topic shows a significant increase since 2008, with a record high of 107 publications in 2022. China dominates the publication list, with thirteen universities contributing the highest. In the context of algal bio-oil, a total of 2850 authors contributed to 1005 publications.
    DISCUSSION: A three-way map displaying the relationships between journal titles, paper titles, and author keywords provides useful insights into the research landscape of the field. Algal research is growing and collaborating, despite bibliometric limitations such as time dependency and database scope. Such studies, however, offer valuable insights into the evolving bio-oil field.
    CONCLUSION: The study aims to link sustainable economic development with technological innovation and related economic growth. Its objective is to provide researchers with information on niche research clusters, quantify emerging methodologies, facilitate collaborative networks, and identify knowledge gaps, while assisting in determining the impact of specific publication venues. In addition to analyzing key economic drivers, the study will also recommend prospective research themes to disseminate algae-based biooil production research.
    Keywords:  Bibliometric analysis; Bio oil; Microalgae; biofuel; green chemistry.
    DOI:  https://doi.org/10.2174/0118722083384019250805103219
  10. Vet World. 2025 Jul;18(7): 1972-1990
    Scopus-based bibliometric analysis of research trends in silage feed and its impact on rumen fermentation in ruminants.
    Tri Rachmanto Prihambodo, Randi Mulianda, Wulandari Wulandari, Santika Anggrahini, Novia Qomariyah, Andi Ella, Erna Winarti, Yenni Yusriani, Suyatno Suyatno, Jhon Firison, Deni Fitra, Anwar Efendi Harahap, Dinda Ayu Permata Sari, Taufik Hidayat, Anuraga Jayanegara.
       Background and Aim: Silage plays a pivotal role in ruminant nutrition, significantly influencing rumen fermentation, animal productivity, and environmental sustainability. Despite extensive research on silage and fermentation, a comprehensive synthesis of global trends and collaborations in this domain has not been systematically explored. This study aimed to conduct a bibliometric analysis of global research on silage feed and its effects on rumen fermentation in ruminants. It sought to identify publication trends, leading contributors, research themes, and international collaboration networks, thereby informing future directions in ruminant nutrition research.
    Materials and Methods: A total of 1,007 documents published between 1961 and 2024 were retrieved from the Scopus database using targeted keywords. Bibliometric and network analyses were performed using VOSviewer, Bibliometrix (R package), and Microsoft Excel. Inclusion criteria were limited to peer-reviewed English-language articles focused on silage feed and rumen fermentation in ruminants. Data cleaning and preprocessing involved harmonization of author names, keywords, and institutional affiliations.
    Results: Publication output has increased significantly since 2010, with China, the United States, and Canada emerging as the top contributors. Major research themes include silage quality, microbial fermentation, methane mitigation, and feed efficiency. Core journals identified include Journal of Dairy Science and Journal of Animal Science. Leading institutions such as China Agricultural University and the University of Florida demonstrated high productivity and citation impact. Keyword analysis highlighted emerging trends, including microbiome, methanogenesis, and sustainability. Collaboration network analysis revealed strong regional clusters, with North America and Europe forming central hubs, while Asia and South America showed growing but less integrated networks.
    Conclusion: Research on silage and rumen fermentation has evolved from foundational studies to interdisciplinary approaches integrating microbiology, environmental science, and precision agriculture. The field is rapidly expanding, with increasing emphasis on reducing methane emissions and enhancing livestock performance through improved silage practices. However, global collaboration remains fragmented, particularly in underrepresented regions. Future research should focus on metagenomics, smart technologies (e.g., Artificial Intelligence and Internet of Things), and policy-driven strategies to optimize feed systems and support sustainable livestock production.
    Keywords:  bibliometric analysis; international collaboration; methane mitigation; microbiome; rumen fermentation; ruminants; silage feed; sustainability
    DOI:  https://doi.org/10.14202/vetworld.2025.1972-1990
  11. Oral Health Prev Dent. 2025 Sep 11. 23 525-534
    Visual Mapping of Global Studies on Dental Hygienists: Trends and Emerging Hotspots.
    Xueli Wan, Xiaorong Zhou, Wenqiang Jiang, Yifan Shen, Yifei Du, Yongle Shi.
       PURPOSE: To analyse the current status and emerging research trends in the field of dental hygienists using a bibliometric analysis.
    METHODS: Relevant literature on dental hygienists published up to 28 January 2025, was retrieved from the Web of Science Core Collection database. Bibliometric and visualisation analyses were conducted using Bibliometrix, VOSviewer, CiteSpace, Pajek, Tableau and Excel.
    RESULTS: A total of 1,835 publications related to dental hygienists were included. The annual number of publications showed a fluctuating upward trend, peaking at 167 articles in 2024. The research involved 94 countries and regions, as well as 209 institutions. The United States had the highest publication output, with the University of Michigan ranking as the most prolific institution. The top three high-frequency keywords were 'dental hygienists' (323 occurrences), 'oral health' (275), and 'dental hygiene' (260). Keyword clustering analysis identified 13 thematic clusters. The most prominent emerging keyword was 'allied dental education'. Notably, 'infection control' and 'health' started to gain prominence in 2022.
    CONCLUSION: Global dental hygiene research centres in North America and Europe, led by US institutions, with evolving priorities from prevention to public health integration, particularly in infection control. These findings inform tailored strategies for developing countries to advance DH professionalisation and address oral health disparities.
    Keywords:  dental hygiene education; dental hygienists; emerging research trends; visualisation analysis
    DOI:  https://doi.org/10.3290/j.ohpd.c_2269
  12. Medicine (Baltimore). 2025 Sep 05. 104(36): e43713
    Research hotspots and emerging trends of artificial intelligence in the clinical management of mild cognitive impairment: A bibliometric and evidence-based analysis.
    Zezhong Zhang, Jianxin Yan, Di Zhang, Kim Jisun, Daojiong Yan.
       OBJECTIVE: This study combines a bibliometric analysis with an umbrella review to delineate the research landscape, hotspots, and emerging trends in the application of artificial intelligence to the clinical diagnosis and treatment of mild cognitive impairment.
    METHODS: We searched the Web of Science Core Collection for literature published between 2004 and 2024. Bibliometric analysis of the retrieved publications was performed using CiteSpace and VOSviewer to map publication trends, international collaboration networks, key contributors, and keyword co-occurrence. From this dataset, we systematically identified and selected eligible systematic reviews and meta-analyses to conduct an umbrella review, thereby synthesizing the highest-level evidence on this topic.
    RESULTS: A total of 3101 publications were included in the analysis, revealing a consistent upward trend in both publication volume and citation frequency. The United States emerged as the most productive country, while the Chinese Academy of Sciences was identified as the leading contributing institution. Ding-gang Shen ranked as the most frequently cited author, and Frontiers in Aging Neuroscience was the most prolific journal in this field. Twelve eligible systematic reviews and meta-analyses primarily focused on topics such as machine learning-based predictive models, neuroimaging and biomarker applications, and cognitive training or intervention strategies.
    CONCLUSION: The application of artificial intelligence in mild cognitive impairment is a rapidly growing field of research. Core research areas include the use of neural networks, electroencephalography, and language processing for diagnostics and monitoring. Emerging research frontiers, such as transfer learning and the investigation of tau pathology pathways, indicate promising directions for future studies.
    Keywords:  artificial intelligence; bibliometric analysis; evidence-based medicine; mild cognitive impairment; neuroimaging techniques
    DOI:  https://doi.org/10.1097/MD.0000000000043713
  13. J Craniofac Surg. 2025 Sep 12.
    From Pioneer to Participant: Bibliometric Evidence of Plastic Surgery's Changing Role in Orbital Fracture Research.
    Daihun Kang.
       BACKGROUND: Orbital fractures lie at the intersection of multiple surgical specialties, yet the intellectual ownership of this domain remains contested. This study aimed to conduct the first comprehensive bibliometric analysis examining plastic surgery's role in global orbital fracture research.
    METHODS: Web of Science Core Collection was searched for orbital fracture-related publications from 2010 to 2024. Analysis included publication trends, geographic distribution, institutional contributions, journal patterns, author productivity, citation analysis, and open access status.
    RESULTS: The search yielded 1444 publications showing steady growth (CAGR 6.7%). United States (426, 29.5%) and South Korea (185, 12.8%) led contributions, with Asian countries collectively producing 30.5% of publications. The Journal of Craniofacial Surgery served as the primary platform with 317 papers (21.9%), demonstrating its central role in disseminating orbital fracture research. Subject category analysis revealed surgery (751, 52.0%), with dentistry/oral surgery comprising 361 (25.0%) publications. Major plastic surgery journals-PRS (1.9%) and Annals of Plastic Surgery (2.1%)-contributed 4.0% combined. Gold open access adoption remains limited at 17%.
    CONCLUSIONS: This analysis reveals the evolving landscape of orbital fracture research, where plastic surgery's traditional leadership faces challenges from increasing multidisciplinary participation. While The Journal of Craniofacial Surgery provides an essential repository for orbital fracture knowledge, strategic initiatives including enhanced open access, focus on high-impact research, and international collaborations could strengthen plastic surgery's intellectual influence. The findings suggest opportunities for plastic surgeons to reinvigorate their foundational role in facial trauma through renewed research commitment and strategic publication approaches.
    Keywords:  Bibliometric analysis; blow-out fracture; blowout fracture; orbital fracture; orbital wall fracture; publication analysis
    DOI:  https://doi.org/10.1097/SCS.0000000000011932
  14. Arq Gastroenterol. 2025 ;pii: S0004-28032025000100206. [Epub ahead of print]62 e25023
    EVOLVING TRENDS AND EMERGING THEMES IN GUT MICROBIOTA RESEARCH: A COMPREHENSIVE BIBLIOMETRIC ANALYSIS (2015-2024).
    Naruaki Ogasawara.
       BACKGROUND: This study aims to analyze research trends and emerging insights into gut microbiota studies from 2015 to 2024 through bibliometric analysis techniques. By examining bibliographic data from the Web of Science (WoS) Core Collection, it seeks to identify key research topics, evolving themes, and significant shifts in gut microbiota research. The study employs co-occurrence analysis, principal component analysis (PCA), and burst detection analysis to uncover latent patterns and the development trajectory of this rapidly expanding field.
    METHODS: This study uses a bibliometric approach to analyze 89,512 gut microbiota research articles published between 2015 and 2024 in the WoS Core Collection. Data preprocessing involved cleaning bibliographic data and identifying the 50 most frequent keywords. A co-occurrence matrix was constructed to capture keyword relationships, and a heatmap visualization illustrated these interconnections. PCA applied for dimensionality reduction, visualizing keyword distributions. Burst detection analysis using Kleinberg's algorithm identified rapidly growing research topics. Finally, the study contextualized its findings by linking results to broader research developments and discussing future research directions and potential opportunities.
    RESULTS: The bibliometric analysis of gut microbiota research from 2015 to 2024 revealed significant trends and emerging themes. The total number of publications on gut microbiota increased approximately 5.82 times during this period, indicating a rapid expansion of the field. Co-occurrence analysis identified key thematic clusters, with "diet", "microbiome", and "immune function" emerging as central research topics. PCA further clarified topic relationships, revealing strong associations between gut microbiota and metabolic diseases, inflammation, and neurological disorders. Burst analysis of key terms demonstrated a shift in research focus, with increasing attention on the role of gut microbiota in precision medicine, neuroinflammation, and host-microbiome interactions. These findings provide a comprehensive overview of gut microbiota research trends, offering insights into critical developments and guiding future investigations into microbiome-based therapies and disease prevention.
    CONCLUSION: This study provides a comprehensive bibliometric analysis of gut microbiota research from 2015 to 2024, highlighting key trends and emerging directions. The findings show that gut microbiota studies have expanded to include diet, health, and disease. The strong link between "diet" and "microbiota" in this study suggests dietary interventions are central to this future research. Rapidly growing keywords like "intestinal", "disease", and "mice" indicate a focus on translational and experimental research. These insights reveal the shifting landscape of gut microbiota research and emphasize the need for further exploration of diet-microbiota interactions, personalized nutrition, and clinical applications.
    DOI:  https://doi.org/10.1590/S0004-2803.24612025-023
  15. JB JS Open Access. 2025 Jul-Sep;10(3):pii: e25.00074. [Epub ahead of print]10(3):
    Inaccuracies in Orthopaedic Research Fellowship Applications: A Study on Authorship Misrepresentations.
    Antonio Fernandez-Perez, Jonathan M Stern, Natalia Cruz-Ossa, Victor H Hernandez, Michele R D'Apuzzo, Colin A McNamara.
       Background: Academic integrity is a cornerstone of scientific research. However, increasing competition may cause applicants seeking competitive positions to report their research contributions inaccurately. An orthopaedic research fellowship offers substantial value for medical students and recent medical graduates to strengthen their applications for a residency position. Misrepresented authorship and publication history may distort applicant evaluations and compromise the credibility of the selection process.
    Materials and Methods: A retrospective cohort analysis was conducted on all applications received during the previous two consecutive application cycles (2024 and 2025) by our adult reconstruction research fellowship located in an academic medical center. Data were collected from all curriculum vitae received, which were cross-referenced with indexed databases to verify publication status and author order. Misrepresentations were categorized into (1) publication discrepancies (nonexistent or withdrawn papers) and (2) exaggerated authorship positions. Descriptive statistics and comparative analysis were performed.
    Results: A total of 87 applications were included in our analysis. Of the 87 applications, 15 (17.2%) were found to have either a publication discrepancy or an exaggerated authorship position. Publication discrepancies occurred in 8 applications (9.2%), while 9 applications (10.3%) demonstrated exaggerated authorship position(s). There were no significant differences between medical student versus medical graduate applicants nor among US medical applicants versus international medical graduate applicants, for number nor types of misrepresentations found.
    Discussion: The increasing competitiveness of orthopaedic surgery residency programs has led applicants to emphasize research productivity as a key component of their applications. However, discrepancies in self-reported research output highlight the potential for misrepresentation. These findings raise ethical concerns regarding honesty in academic reporting. Even minor misrepresentations can undermine the integrity of the application process, diminish trust among reviewers, and compromise the fairness of candidate evaluation. Implementing systems such as Open Researcher and Contributor ID could enhance transparency, ensure accurate attribution, and mitigate inconsistencies in research reporting, ultimately improving the research fellowship application process.
    DOI:  https://doi.org/10.2106/JBJS.OA.25.00074
  16. Open Res Eur. 2024 ;4 268
    Mapping leadership and communities in EU-funded research through network analysis.
    Fabio Morea, Alberto Soraci, Domenico De Stefano.
       Background: Horizon 2020 and Horizon Europe are flagship programs of the European Union aimed at supporting research and innovation, fostering collaboration among companies, academic institutions, and research organizations. Comprehensive data on projects, objectives, participants, funding details, and results of Horizon projects is available through the open access portal CORDIS (Community Research and Development Information Service). This paper introduces a novel methodology for utilizing CORDIS data to reveal collaborations, leadership roles, and their evolution over time.
    Methods: The methodology is based on network analysis. Data is downloaded from the CORDIS portal, enriched, segmented by year and transformed into weighted networks representing collaborations between organizations. Centrality measures are used to assess the influence of individual organizations, while community detection algorithms are used to identify stable collaborations. Temporal analysis tracks the evolution of these roles and communities over time. To ensure robust and reliable results, the methodology addresses challenges such as input-ordering bias and result variability, while the exploration of the solution space enhances the accuracy of identified collaboration patterns.
    Results: To illustrate the approach, the methodology is applied to a specific case: analyse the evolution of collaborations in hydrogen valleys, in the broader frame of "hydrogen energy" research and innovation projects funded by Horizon programmes.
    Conclusions: The proposed methodology effectively identifies influential organizations and tracks the stability of research collaborations. The insights gained are valuable for policy-makers and organizations seeking to foster innovation through sustained partnerships. This approach can be extended to other sectors, offering a framework for understanding the impact of EU research funding on collaboration and leadership dynamics.
    Keywords:  Community Detection; Horizon 2020; Horizon Europe; Hydrogen; Hydrogen Valley; Innovation; Network Analysis
    DOI:  https://doi.org/10.12688/openreseurope.18544.2
  17. JTCVS Open. 2025 Aug;26 321-328
    Trans-Atlantic analysis of gender representation in general thoracic surgery: Challenges permeate the academic community.
    Rajika Jindani, Debora Brascia, Albert Dweck, Javeria Tariq, Justin Olivera, Amanda Ghanie, Jorge Humberto Rodriguez-Quintero, Mara B Antonoff, Brendon M Stiles, Cecilia Pompili.
       Objective: The underrepresentation of women in thoracic surgery has been well described worldwide. Women can serve as role models for trainees and advance their careers through academic appointments, leadership positions, and involvement in thoracic societies. We aimed to characterize differences between representation of women in thoracic surgery in the United States and Europe.
    Methods: A cross-sectional study was conducted using publicly available data for hospitals with 30 general thoracic-track training programs in the United States and Europe from December 2023 to May 2024. Membership data for national/international societies were obtained directly from respective organizations.
    Results: Among 30 US institutions with dedicated general thoracic surgery training tracks, women comprised 17.7% (102 out of 475) of faculty, compared with those of 30 general thoracic surgery centers in 8 European countries, where women comprised 29.5% (79 out of 268) of faculty. Of programs with available data, 26.7% (8 out of 30) had women as thoracic surgery program directors in the United States and 13% (4 out of 30) in Europe. Regarding societal membership in the General Thoracic Surgical Club (United States) and European Society of Thoracic Surgeons (Europe), women were well represented as trainee members (United States, 39.2% [20 out of 51] vs Europe, 46.1% [113 out of 245]; P = .367), but comprised a lower proportion of active/senior members (United States, 12.9% [45 out of 349] vs Europe, 19.2% [283 out of 1474]; P = .006).
    Conclusions: We identified universal disparities in the representation of women in faculty appointments, leadership positions, and membership in professional societies. Efforts to address imbalances may benefit from shared experiences and initiatives, aiding resident recruitment and career advancement for women thoracic surgeons while fostering diversity, equity, and inclusion on a global scale.
    Keywords:  and inclusion; diversity; equity; gender disparities; thoracic surgery; workforce analysis
    DOI:  https://doi.org/10.1016/j.xjon.2025.06.006
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