bims-evares Biomed News
on Evaluation of research
Issue of 2025–07–27
eighty-one papers selected by
Thomas Krichel, Open Library Society
  1. A bibliometric analysis of clear aligner therapy research articles published over 5 years - 2020-2024.
  2. Classic Publications in the Field of Dentistry: A Bibliometric Analysis.
  3. A bibliometric mapping study of the literature on the quality of life of people living with HIV.
  4. Research trends and hotspots in the mental health of widowed older adults: a bibliometric analysis.
  5. A Global Bibliometric Analysis of Publications on Recurrent Atrial Fibrillation After Radiofrequency Ablation.
  6. A bibliometric and visualized analysis of research on mitochondria in myocardial ischemia from 2015 to 2024.
  7. The top 50 most cited articles on superior capsular reconstruction: a bibliometric analysis.
  8. Global trends and frontiers in iNKT cells: a bibliometric and visualized analysis.
  9. Research Trends and Hotspots of Acupuncture Therapy on Allergic Diseases From 2004 to 2024: A Bibliometric Analysis.
  10. Knowledge mapping of Specific Language Impairment in children: A bibliometric analysis (2010-2024).
  11. Application of ultrasound in liver cancer from 2014 to 2024: bibliometric analysis and global trends.
  12. Research trends in Rift Valley fever virus: a bibliometric analysis from 1936 to 2024.
  13. The Landscape of Pelvic Floor Rehabilitation: A Bibliometric Analysis.
  14. Non-suicidal self-injury in adolescent depression: A bibliometric study and visualization analysis.
  15. Mapping the research trends and hotspots on solid pulmonary nodules from 2000-2024: insights from bibliometric analysis.
  16. Bibliometric and Visual Analysis of Global Trends in Obstructive Sleep Apnea and Bariatric Surgery from 1998 to 2024.
  17. Trends and emerging frontiers of photodynamic therapy for non-melanoma skin cancer (1979-October 2024): a bibliometric analysis.
  18. Rate and trends of women authorship in a high-impact French orthopaedic journal over 30 years.
  19. Insulin resistance and Alzheimer's disease: Exploring research hotspots and frontiers from a bibliometric and visual analysis (2005-2024).
  20. Trends in research related to anxiety disorders on the autism spectrum: a bibliometric study.
  21. Historical and Emerging Trends in Hepatitis B Virus Integration: A Bibliometric Visual Analysis.
  22. Resilience and Recalibration of Bibliometric Indicators in Neurosciences and Neuropharmacology Journals After COVID-19: A Longitudinal Rate of Change Analysis Using Mixed-Effects Models.
  23. Emerging trends in Alzheimer's disease diagnosis and prediction using artificial intelligence: A bibliometric analysis of the top cited 100 articles.
  24. Oxidative Stress in Dry Eye Disease: A Bibliometric Analysis.
  25. Research hotspots and current status of iliotibial band studies: A bibliometric analysis (1934-2023).
  26. Trends and hotspots in cupping therapy research for pain: a bibliometric study.
  27. Global research trends and hotspots in prognostic prediction models for pancreatic cancer: a bibliometric analysis.
  28. A bibliometric analysis of liver cancer bone metastases: advances in mechanisms of occurrence and treatment options.
  29. Overview of scientific productivity in the field of fungal stress research.
  30. Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis.
  31. Two decades of research in occupational physical activity for health: A bibliometric analysis.
  32. Global Leadership Initiative on Malnutrition: a bibliometric analysis of research trends and contributions (2018-2024).
  33. Hydrogels in cancer treatment: mapping the future of precision drug delivery.
  34. Sexual Health in Bariatric Surgery: A Bibliometric Study.
  35. Tibial shaft fractures: A bibliometric analysis of the top 50 most cited publications.
  36. Research trends between acquired immune deficiency syndrome and hematological malignancies: a bibliometric analysis.
  37. Acupuncture for Chronic Obstructive Pulmonary Disease: A 38-Year Bibliometric Landscape of Global Research Trends and Knowledge Evolution (1986-2024).
  38. A Comparison of OpenAlex With Scopus and Web of Science for Tracking Scholarly Nursing Literature.
  39. Bibliometric and visualization analysis of hydrogel research in spinal cord injury: comparative study of Chinese and English literature.
  40. Erratum to "Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis".
  41. Bibliometric analysis and visualization mapping of herpes zoster vaccine publications from 1999 to 2024.
  42. The growing interests in Epstein-Barr virus: A bibliometric analysis of research trends, collaborations, and emerging hotspots.
  43. Global research dynamics in the induced pluripotent stem cell and diabetes: A bibliometric analysis of the past twenty years.
  44. Global Research Trends in Biomimetic Lattice Structures for Energy Absorption and Deformation: A Bibliometric Analysis (2020-2025).
  45. NLRP3 Inflammasome: A New Perspective on Revealing Hotspots and Trends in Uric Acid Metabolism Disorders through Bibliometric Analysis.
  46. Nutrition in palliative care at the end of life: Bibliometric and network analysis until 2024.
  47. Research Hotspots and Frontiers of Ischemic Stroke and Traditional Chinese Medicine: A Knowledge Mapping and Text Mining Analysis.
  48. Predicting the unseen: nutritional interventions as a key to combat frailty.
  49. Emotional climate: a bibliometric analysis of the psychological consequences of climate change.
  50. Bibliometric analysis of colchicine in cardiovascular health: trends, key contributors, and global collaborations.
  51. Corrigendum: Mapping knowledge structure and research of the biologic treatment of asthma: a bibliometric study.
  52. Research on medical errors exhibits diverse associations with global indicators of science, development, and health across geographic regions: A scientometrics study.
  53. Immunotherapy and combination treatments for triple-negative breast cancer: a Scopus bibliometric perspective.
  54. Bibliometric analysis of global research trends in pancreatic cancer immunotherapy.
  55. Bibliometric Analysis: Insights Into the Podiatric Medicine Landscape of Diabetic Sensory Peripheral Neuropathy and Genomics.
  56. Exploring Gender-Based Barriers in Physician Assistant Educator Authorship: Insights From a Physician Assistant Author Survey.
  57. Letter: The Bibliometric Evolution of Neurosurgery Publications From 1977 to 2023.
  58. Advancements and Scientific Partnerships in the Application of Polysaccharides in Oral Formulations: A Bibliometric Analysis and Review.
  59. From residency to research excellence, mapping orthopaedic publication trends: A scoping review.
  60. The interplay between migration and self-identity: a structured review using TCCM and bibliometric analysis.
  61. Exploring the emerging trends and hot topics of 5G technology application in wireless medicine: A bibliometric and visualization analysis.
  62. Academic metrics and publication history of presenters at the American Shoulder and Elbow Surgeons closed annual conferences from 2016 to 2022.
  63. Global research trends of neuroinflammation in perioperative neurocognitive dysfunction: a bibliometric analysis.
  64. From Podium to PubMed: Successful Manuscript Publication of Oral Breast Surgery Abstract Presentations at National Meetings from 2017 to 2022.
  65. [Frontier technologies and development trends of network pharmacology: a patent bibliometric analysis].
  66. GLOBAL COLLABORATION IN UROLOGICAL SURGERY RESEARCH BETWEEN HIGH- AND LOW-INCOME COUNTRIES: A BIBLIOMETRIC SCOPING REVIEW.
  67. In Reply: The Bibliometric Evolution of Neurosurgery Publications From 1977 to 2023.
  68. Applications of Traditional Herbal Ingredients in Skincare: Mapping the Research Landscape and Innovation Trajectories Over Four Decades.
  69. Bibliometric Analysis of Juvenile Idiopathic Arthritis From 2012 to 2023.
  70. Who Leads Psychiatry? Demographics, Educations, and Scientific Contributions of US Academic Chairs.
  71. Trajectories and connections in socio-environmental disclosure research: A bibliometric mapping.
  72. Erratum: Bibliometrics and Visualization Analysis of Neuromuscular Junction Model.
  73. Current status and significance of research on sex differences in neuroscience: a narrative review and bibliometric analysis.
  74. How getting tenure changes researchers' publication habits - and citations.
  75. Tenure and research trajectories.
  76. Systematic review and meta-analysis of quotation inaccuracy in medicine.
  77. Influence of Social Media on the Dissemination and Uptake of Cardiology Research.
  78. Nanomedicine in fungal keratitis: current applications and future prospects.
  79. Perception of nurse academicians on academic publications: A cross-sectional study.
  80. 'Wandering scholars' analysis reveals how location drives productivity.
  81. Limitations and recommendations for bibliometric insights into breast cancer organoid chips: trends & emerging areas- a commentary.
  1. Int Orthod. 2025 Jul 17. pii: S1761-7227(25)00074-9. [Epub ahead of print]23(3): 101039
    A bibliometric analysis of clear aligner therapy research articles published over 5 years - 2020-2024.
    Maurice J Meade, Ting-Han Lin, Tony Weir.
       OBJECTIVE: To identify and evaluate research articles regarding clear aligner therapy (CAT) published between 2020 and 2024 inclusive.
    METHODS: A systematic strategy was employed to search the Web of Science Core Collection (Clarivate Analytics, Philadelphia, Pa) and the Incites Journal Citation Reports (Clarivate Analytics) databases for records regarding CAT-related articles published between 2020 and 2024 inclusive. Authorial and journal metrics and information regarding study type were documented.
    RESULTS: A total of 975 articles satisfied inclusion criteria and were evaluated. The number of CAT-related publications more than quadrupled from 2020 (n=84) to 2024 (n=341). Articles were published in a total of 166 journals or other publication sources. The American Journal of Orthodontics (n=100; 10.3%) and the Angle Orthodontist (n=56; 5.7%) are the journals in which CAT-related research were mostly published. Both journals recorded the joint highest number of places (n=6; 20%) in the list of top 50 cited articles published within the timeframe. The mean (SD) number of authors per article was 5.3 (2.3) [Maximum 25; Minimum 1], with first authors being affiliated to a total of 52 countries. China is the country of affiliation most frequently reported by first authors (n=198; 20.3%) followed by Italy (n=161; 16.5%). Retrospective observational (n=196; 20.1%) and in vitro studies (n=190; 19.5%) were the two most common study types with 2.6% (n=25) being randomised clinical trials.
    CONCLUSION: The findings will provide insight for scholars and clinicians regarding current research trends and identify research methodologies which may help determine the nature of future studies.
    Keywords:  Bibliometric study; Clear aligner therapy; Orthodontics; Research methodology
    DOI:  https://doi.org/10.1016/j.ortho.2025.101039
  2. Int Dent J. 2025 Jul 17. pii: S0020-6539(25)00198-4. [Epub ahead of print]75(5): 100909
    Classic Publications in the Field of Dentistry: A Bibliometric Analysis.
    Yuh-Shan Ho, Nikolaos Christidis.
       INTRODUCTION AND AIMS: This bibliometric study aimed to identify and analyze the classic articles in the Web of Science category 'Dentistry, Oral Surgery and Medicine,' providing insights into the characteristics, citation patterns, and evolving trends that define the field's most influential publications.
    METHODS: Articles published between 1960 and 2020 were extracted from the Science Citation Index Expanded (SCI-EXPANDED) database. Classic articles were defined as those with ≥1000 citations as of the end of 2024. Bibliometric indicators such as total citations (TC2024), citations in 2024 (C2024), citations per publication (CPP2024), and authorship patterns were analyzed. Citation trajectories, author keywords, and institutional and international collaborations were also assessed.
    RESULTS: A total of 42 classic articles were identified. These publications were most frequently produced in the 1990s and 2000s and originated predominantly from the USA and Sweden. The University of North Carolina and the University of Gothenburg were particularly prominent. Periodontology, implantology, dental materials, and oral epidemiology were common themes. Articles such as Socransky et al. and Schiffman et al. demonstrated both sustained and recent citation influence. Word frequency analysis highlighted topics such as plaque, periodontal disease, and classification systems. Citation histories revealed diverse trajectories, including delayed recognition and rapid recent influence.
    CONCLUSION: Classic articles in dental research reflect the field's shift toward evidence-based practice, interdisciplinary collaboration, and public health relevance. By mapping these highly cited works, this study provides a clearer understanding of the factors contributing to long-term scientific impact in dentistry, oral surgery, and medicine.
    CLINICAL RELEVANCE: This study identifies highly cited publications that have shaped clinical practice in periodontology, implantology, temporomandibular disorders, wound healing, and oral-systemic health. These works continue to guide diagnostics, treatment planning, and public health strategies, highlighting the lasting impact of foundational research and the importance of interdisciplinary, evidence-based approaches in dentistry.
    Keywords:  Classic articles; Dentistry; Oral surgery and medicine; SCI-EXPANDED; Scientometrics
    DOI:  https://doi.org/10.1016/j.identj.2025.100909
  3. AIDS Res Ther. 2025 Jul 18. 22(1): 69
    A bibliometric mapping study of the literature on the quality of life of people living with HIV.
    Can Huang, Yanfang Sun, Meng Chen, Lin Zhang, Wei Liu.
       BACKGROUND: In recent years, owing to the implementation of highly active antiretroviral therapy (HAART), human immunodeficiency virus (HIV) has become a manageable chronic disease. Consequently, the quality of life (QOL) of people living with HIV (PLWH) has warranted increasing attention. Although a substantial number of articles on QOL among PLWH have been published, statistical analysis of the data presented in these publications remains lacking. This study aimed to identify and analyze emerging trends and collaborative networks in research on the QOL of PLWH.
    METHODS: Research publications on the QOL of PLWH from 1992 to 2025 were collected from the Web of Science Core Collection. After screening and deduplication, the following bibliometric data were extracted from each article: title, abstract, keywords, authors, affiliations, geographic origin (countries/regions), publication year, journal name, and references. Various scientometric mapping tools-including Microsoft Office Spreadsheet, VOSviewer, and the Bibliometrix R-package-were used to analyze basic bibliometric parameters, leading contributors, high-impact keywords, and research trends.
    RESULTS: A total of 6,163 publications met the inclusion criteria. Over the past 33 years, the annual number of publications has shown an overall upward trend. The United States had the highest number of publications (n = 2,432) and the highest total link strength (TLS = 1,798) in collaborative research. The University of California, San Francisco, served as the core institution, and PLOS ONE was the most prolific journal. Wu AW was identified as a core member of the industry collaboration network. By combining keyword co-occurrence and co-citation analyses, this study found that clinical concerns (e.g., antiretroviral therapy adherence, depression, anxiety) remained prominent, while stigma, healthcare access, and age-related impairments emerged as the latest hotspots with strong burst strength.
    CONCLUSIONS: This bibliometric analysis highlights the growing importance of QOL research in the field of PLWH, which can inform clinicians, researchers, and policymakers to prioritize areas for future investigation in order to develop comprehensive, patient-centered strategies. The findings advocate for appropriate resources for interventions that benefit HIV populations and a better understanding of the psychosocial needs of PLWH to improve their QOL.
    Keywords:  Bibliometric analysis; Hotpots; Human immunodeficiency virus; Quality of life; Stigma
    DOI:  https://doi.org/10.1186/s12981-025-00772-2
  4. Front Psychiatry. 2025 ;16 1612813
    Research trends and hotspots in the mental health of widowed older adults: a bibliometric analysis.
    Doudou Lin, Jiaojiao Wu, Weibing Chen, Xiangying Shen, Zhongxiang Cai, Nian Wang, Dou Fu, Yinglin Li, Xiaojie Ma.
       Background: The mental health of widowed older adults has garnered increasing research attention due to its profound impact on well-being and quality of life. Despite growing scholarly interest, a comprehensive bibliometric analysis of evolving research trends, key topics, and knowledge structures remains scarce. This study aims to identify key research themes, emerging trends, and interdisciplinary linkages to inform future studies on the mental health of widowed older adults.
    Methods: A bibliometric analysis was conducted using data from the Web of Science Core Collection (2004-2024). CiteSpace, VOSviewer, and the R package "Bibliometrix" were utilized to visualize publication trends, country and author collaborations, keyword co-occurrences, theme analysis, and emerging research topics.
    Results: A total of 891 articles were analyzed. The United States produced the highest number of publications, followed by China and the United Kingdom, with the United States, England, and Canada exhibiting strong research collaborations. Depression, prevalence and mental health were identified as core research themes, while life satisfaction and social support emerged as growing areas of interest. Citation burst and thematic evolution analyses revealed shifting scholarly interest from clinical and diagnostic concerns towards psychosocial adaptation and person-centered approaches over time.
    Conclusion: This bibliometric study systematically maps the research landscape, hotspots, and emerging trends in the mental health of widowed older adults over the past two decades. The findings provide valuable insights for researchers seeking to identify key research directions, foster interdisciplinary collaborations, and develop targeted interventions to support the mental well-being of widowed older adults.
    Keywords:  Citespace; VOSviewer; bibliometric analysis; mental health; older adults; widowhood
    DOI:  https://doi.org/10.3389/fpsyt.2025.1612813
  5. Cureus. 2025 Jun;17(6): e86396
    A Global Bibliometric Analysis of Publications on Recurrent Atrial Fibrillation After Radiofrequency Ablation.
    Mehmet Semih Belpinar.
      Radiofrequency ablation for atrial fibrillation (AF) has become the standard therapy due to its high efficacy and recurrent complication potential. With the increased prevalence of cardiovascular diseases in an aging population, effective management remains a challenge. It is an area of active research and clinical emphasis, advancing ablation techniques that can provide new opportunities to optimize outcomes and minimize recurrence. The aim of this bibliometric investigation was to assess the publications of recurrent AF after radiofrequency ablation. A thorough bibliometric analysis was performed using publicly available and subscription-based data obtained from the Web of Science database on the publications concerning recurrent AF following radiofrequency ablation. The present study focused on a qualitative analysis of publication volume trends and patterns in languages, affiliations, publishing houses, journals, countries, year-by-year publication, category, and co-occurrence of the major keywords. The number of publications on recurrent AF after radiofrequency ablation has risen dramatically, with 276 studies involving 1763 researchers from 359 institutions in 35 countries. A total of 68.48% of papers are articles, while meeting abstracts contribute 25%, and review articles comprise 4% of the total. The number of publications has sharply increased in recent years, particularly in 2023 and 2024, with the highest number of publications being published in 2024. The average citations per document for the 10 most cited publications were 15.43. Important studies have provided essential insight into AF recurrence, while other studies have investigated predictors of AF recurrence, such as left atrial volume, as well as sleep apnea and corticosteroid therapy. China is the most voluminous contributor to the field, with 122 publications and 591 citations. Among the most remarkable countries, institutions, and journals, Japan and South Korea hold a significant share. Notably, Japan's University of Tsukuba stands out with a high citation count despite a relatively low number of publications. In total, the articles have been published across 96 journals, with the European Heart Journal contributing the highest number of publications. Topics such as ablation techniques, atrial fibrosis, and predictors of recurrence are increasingly prominent, reflecting the rapidly evolving landscape of this research domain. There has been a dramatic increase in relevant publications, with China at the center of production and cooperation. Landmark studies have significantly improved our understanding of recurrence predictors and treatment outcomes. New trends in ablative techniques, as well as factors surrounding recurrence, continue to highlight progression within the field.
    Keywords:  atrial fibrillation recurrences; bibliometric analysis; publications; radiofrequency ablation; recurrent atrial fibrillation after radiofrequency ablation; visual analysis
    DOI:  https://doi.org/10.7759/cureus.86396
  6. Front Cardiovasc Med. 2025 ;12 1547604
    A bibliometric and visualized analysis of research on mitochondria in myocardial ischemia from 2015 to 2024.
    Yang Lu, Fanghe Li, Qiong Wu, Qingteng Zhai, Xinyi Li, Weibin Xie, Shuwen Guo, Kuo Gao.
       Background: Mitochondria, as the powerhouse of myocardial energy metabolism, have garnered considerable interest in the realm of myocardial ischemia (MI) therapy research. The purpose of this study is to illustrate the hot spots and frontiers of mitochondrial research in MI in the past decade through bibliometric analysis.
    Methods: Both articles and reviews of mitochondrial research in MI from 2015 to 2024 were retrieved from the Web of Science Core Collection database. Bibliometric analysis was performed mainly using CiteSpace and VOSviewer.
    Results: The analysis encompassed 4,387 papers. The annual publications exhibited a significant increasing trend, rising from 342 publications in 2015 to 541 publications in 2024. China, the United States of America, and Germany emerged as the top three contributors to MI related mitochondria studies. The Air Force Medical University, China, was the leading publisher. Chattipakorn, Nipon (Chiang Mai University), Chattipakorn, Siriporn C (Chiang Mai University), Zhou, Hao (Zhejiang University) were the top three most active and influential scholars based on the H-index. International Journal of Molecular Sciences was the most co-cited journal in this field. Until 2024, the keywords with the strongest citation bursts included mitophagy, transplantation, homeostasis, and myocardial ischemia-reperfusion. The current research trend is to translate mitochondria-related diagnostic and therapeutic drugs for MI into the clinic.
    Conclusions: Exploring MI from a mitochondrial perspective has great potential. By revealing the knowledge structure of this field, this study helps to provide scholars in related fields with a comprehensive understanding of the field and develop collaborations.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; hotspots; mitochondria; myocardial ischemia; visualization
    DOI:  https://doi.org/10.3389/fcvm.2025.1547604
  7. JSES Rev Rep Tech. 2025 Aug;5(3): 516-522
    The top 50 most cited articles on superior capsular reconstruction: a bibliometric analysis.
    Mallery Zeiman, Lee Beauchamp, Ryan S Marder, Anthony J Scillia.
       Background: Bibliometric analysis has been used to quantify and assess a scientific publication and its impact. The purpose of this study was to identify and review the top 50 most cited articles discussing superior capsular reconstruction (SCR).
    Methods: Scopus database was used to search for publications focusing on SCR. The top 50 most cited articles that met the inclusion criteria were reviewed for year and journal of publication, country of origin, study type, level of evidence, and citation density.
    Results: The total number of citations from the top 50 articles was 2048 (range, 10-196). The year of publication ranged from 2015 to 2022, with the majority (n = 42) being published from 2018 to 2022. The most common level of evidence rating was level V (21 articles) and the majority (81%) of these articles were surgical technique notes. The second most common level of evidence rating was level IV (16 articles) which were all case series. The articles were written across 16 different countries, most commonly the United States (52%), and published in 16 different journals.
    Conclusion: Most of the top 50 articles on SCR were technical notes and case series. This demonstrates the need for higher level, comparative, and controlled studies examining SCR techniques, outcomes, and complications in the future.
    Keywords:  Bibliometric analysis; Irreparable rotator cuff tear; Massive rotator cuff tear; SCR; Superior capsular reconstruction; Top 50 articles
    DOI:  https://doi.org/10.1016/j.xrrt.2025.03.005
  8. Front Immunol. 2025 ;16 1618254
    Global trends and frontiers in iNKT cells: a bibliometric and visualized analysis.
    Dan Zhang, Jun Lu.
       Background: Invariant natural killer T (iNKT) cells are an unconventional lymphocyte subset that has garnered increasing attention due to their shared features with both natural killer cells and conventional T cells, as well as their unique dual immunological functions. In this study, we conducted a comprehensive bibliometric analysis to trace the evolution of research in the iNKT cell field, identify emerging trends, and highlight current research hotspots and frontier directions.
    Methods: We performed a literature search in the Web of Science Core Collection database to retrieve all publications related to iNKT cells published to December 31, 2024. We then used the visualization tools CiteSpace and VOSviewer to conduct a bibliometric analysis of the retrieved data.
    Results: We identified 2,579 relevant publications authored by 12,108 individuals from 2,218 institutions across 70 countries. These publications appeared in 540 journals and collectively cited 60,342 references from 4,322 different journals. The publication volume in the iNKT cell field has significantly increased since 2008, peaking at 151 articles in 2018. This surge highlights the sharp rise of research interest in this area. The United States led in publication output within this field. Among the journals, the Journal of Immunology was the most prolific and also ranked first in total citations. Besra was the most published author, while Bendelac's research was highly influential. Research on iNKT cells is undergoing a paradigm shift from mechanistic exploration to clinical application.
    Conclusions: Our bibliometric analysis delineates the thematic evolution within the iNKT cell research landscape. Future investigations will converge on several pivotal frontiers, including improving the tumor microenvironment, reprogramming the functional activity of iNKT cells within tumors, and advancing engineered immunotherapies. Additionally, strategies to engineer iNKT cells for more targeted and effective therapeutic interventions are likely to gain momentum, as researchers aim to overcome the current limitations in the field and transition from basic mechanistic studies to more impactful clinical applications.
    Keywords:  antigen; bibliometric; immune response; immunotherapy; invariant natural killer T cells
    DOI:  https://doi.org/10.3389/fimmu.2025.1618254
  9. J Multidiscip Healthc. 2025 ;18 4071-4087
    Research Trends and Hotspots of Acupuncture Therapy on Allergic Diseases From 2004 to 2024: A Bibliometric Analysis.
    Yanrong Lv, Ziyi Jiang, Jingwen Zhang, Xiaoyan Zheng, Xiaoping Tian, Jia Liu, Jie Yang.
       Background: Over the past two decades, acupuncture has increasingly been applied in the treatment of allergic diseases, with a corresponding increase in the number of published articles.
    Objective: To investigate the hotspots and frontiers of global scientific output in acupuncture research for allergic diseases over the past two decades.
    Methods: The Web of Science Core Collection was used to collect literature on acupuncture therapy for allergic diseases, which spanned from 2004 to 2024. We used CiteSpace 6.3.1 and VOSviewer to conduct visual analysis of the relevant contents of the literature, and constructed a network graph in the software by using information such as the publication date of the article, country, institution, author, and journal.
    Results: A total of 423 documents were retrieved. The results indicate that the annual publication volume on acupuncture treatment for allergic diseases has shown a fluctuating upward trend. China is the leading country in terms of publications. KyungHee University emerges as the most productive institution. Brinkhaus, B. is the most prolific author. Medicine is the most popular journal. Annals of Internal Medicine has the highest impact factor. Allergic rhinitis, the efficacy and safety of acupuncture as an alternative therapy for allergic diseases, and the mechanisms underlying acupuncture treatment are at the forefront of research in this field.
    Conclusion: This study provides a comprehensive summary of the research hotspots and trends in the field of acupuncture treatment for allergic diseases over the past two decades, which can assist researchers in better understanding the development of this field and offer directions for future research.
    Keywords:  VOSviewer; acupuncture; allergic diseases; bibliometric analysis; citespace
    DOI:  https://doi.org/10.2147/JMDH.S528646
  10. Appl Neuropsychol Child. 2025 Jul 21. 1-16
    Knowledge mapping of Specific Language Impairment in children: A bibliometric analysis (2010-2024).
    Zhengyun Hu, Feifei Luo, Qianqian Yao, Tao Zhang, Xianhui Hong, Lifei Zhang, Feng Jiang, Zhuyun Ding.
       BACKGROUND: Specific Language Impairment (SLI), increasingly termed Developmental Language Disorder (DLD), affects 7-10% of children worldwide. Despite expanding research, no comprehensive bibliometric analysis has systematically examined this field's evolution.
    METHODS: We analyzed 4,966 SLI/DLD-related publications (2010-2024) from the Web of Science Core Collection using VOSviewer, CiteSpace, and bibliometrix to assess publication trends, collaboration networks, citation patterns, and research themes.
    RESULTS: Publication output increased 256% over the study period, with the United States (41.1%) and England (13.1%) dominating contributions. The University of Toronto, University of Melbourne, and University College London emerged as leading institutions. The Journal of Speech, Language, and Hearing Research(JSLHR) was most influential. Research evolved through three phases: linguistic components (2012-2016), neurodevelopmental mechanisms (2016-2020), and holistic therapies (2020-2024). Key themes included methodological frameworks, comorbidities with neurodevelopmental disorders, and intervention strategies.
    CONCLUSION: This first comprehensive bibliometric analysis reveals SLI/DLD research evolving from isolated linguistic investigations toward integrated neurodevelopmental frameworks and therapeutic approaches. The field shows increasing recognition of shared mechanisms across developmental conditions and growing emphasis on early intervention. Our findings highlight critical research directions including expanded international collaboration, cross-disorder research exploring shared neurobiological mechanisms, longitudinal intervention studies, and technology-enhanced assessment methodologies.
    Keywords:  Bibliometric analysis; Specific Language Impairment; citation analysis; developmental language disorder; research trends
    DOI:  https://doi.org/10.1080/21622965.2025.2520462
  11. Discov Oncol. 2025 Jul 23. 16(1): 1395
    Application of ultrasound in liver cancer from 2014 to 2024: bibliometric analysis and global trends.
    Yaping Zhu, Yanyan Lu, Xinju Chen.
       BACKGROUND: Liver cancer remains one of the most prevalent and lethal malignancies worldwide, highlighting the need for effective diagnostic and monitoring strategies. Ultrasound plays a vital role in the early diagnosis, monitoring, and treatment of liver cancer. However, no bibliometric analysis has been conducted in this field before. This study aims to provide a comprehensive overview of the knowledge structure and research hotspots related to the application of ultrasound in liver cancer via bibliometric methodologies.
    METHODS: A search was performed in the Web of Science Core Collection database for English literature studies on the application of ultrasound in liver cancer from 2014 to 2024. Bibliometric analysis tools including VOSviewer, CiteSpace, and R Studio, were utilized to analyze global trends and research hotspots in this field.
    RESULTS: A total of 2501 eligible publications, including 2048 articles and 453 reviews, were analyzed. In the past decade, both the annual output of publications and the citation rates have rapidly increased. The majority of published articles on this topic were originated in China (n = 832, 33.27%), followed by the United States (n = 586, 23.43%), and Italy (n = 222, 8.88%). Researchers from the United States have demonstrated high productivity, prominence, and influence in this area of research. Additionally, Sun Yat-sen University published the most papers (n = 64), whereas the University of Michigan had the highest average citation value (value = 60.28) related to research on the application of ultrasound in liver cancer. Notably, Singal, Amit G from the USA was the author with both the highest number of published articles and the highest average citation value.
    CONCLUSION: In recent years, rapid advancements in ultrasound research for liver cancer have been reported. Increasing evidence has illustrated the crucial role of ultrasound in the early diagnosis and monitoring of liver cancer.
    Keywords:   Bibliometric analysis; Liver cancer; Trends; Ultrasound
    DOI:  https://doi.org/10.1007/s12672-025-03177-9
  12. Front Vet Sci. 2025 ;12 1611642
    Research trends in Rift Valley fever virus: a bibliometric analysis from 1936 to 2024.
    Huiying Zhang, Shuai Song, Leiliang Zhang.
       Background: Rift Valley fever (RVF), first identified in Kenya in 1930, is a viral zoonosis transmitted by arthropods and poses significant risks to both public and animal health. Despite the wealth of published studies on the disease, the number of bibliometric analysis of Rift Valley fever virus (RVFV) is limited. This study utilized bibliometric analysis to identify research hotspots and emerging trends in RVFV studies, aiming to offer new insights and strategic references for future research directions and prevention strategies.
    Methods: The study utilized Scopus to collect global publications on RVFV from 1936 to 2024. Data processing and visualization were performed with VOSviewer, CiteSpace, Scimago Graphica, and the Bibliometrix web tool.
    Results: A total of 1,629 publications related to RVFV were included in this analysis. Geographic distribution showed that the United States, France, and Kenya were the most productive countries in this field, while Institut Pasteur emerged as the leading research institution. PLoS Neglected Tropical Diseases was identified as the predominant journal for publishing RVFV research, while Virology received the highest citation frequency. Author analysis revealed Clarence Peters as the most prolific contributor, with "Rift Valley fever virus" being the most frequently used keyword.
    Conclusion: This bibliometric investigation systematically assessed nine decades of research on RVFV, providing a comprehensive overview of the contributions from leading nations, institutions, researchers, and journals in this field. Global interest in RVFV research has been steadily increasing, particularly in recent years. This surge in attention, largely influenced by climate change, has attracted heightened focus from public health departments.
    Keywords:  CiteSpace; RVF; RVFV; VOSviewer; bibliometric
    DOI:  https://doi.org/10.3389/fvets.2025.1611642
  13. Int Urogynecol J. 2025 Jul 24.
    The Landscape of Pelvic Floor Rehabilitation: A Bibliometric Analysis.
    Jie Hao, Zixuan Yao, Andréas Remis, Xin Yu, Yuxiao Sun.
       BACKGROUND AND PURPOSE: Pelvic floor rehabilitation is a specialized therapeutic approach focused on assessing and treating pelvic floor muscle dysfunction to enhance bladder, bowel, and sexual function, as well as pelvic organ support, through targeted exercises and behavioral interventions. While applicable to all populations across the lifespan, it holds particular importance for women due to the high prevalence of pelvic floor disorders. As research in this field has grown rapidly, a comprehensive overview is needed to map its development and guide future directions. This bibliometric analysis aims to analyze publication trends, assess current knowledge, and investigate thematic structure in pelvic floor rehabilitation research.
    METHODS: A bibliometric analysis was conducted using the Web of Science Core Collection (coverage from 1900 to present). Articles and reviews published in English from database inception to December 2024 were included. VOSviewer and CiteSpace were employed to perform co-authorship, co-occurrence, co-citation, bibliographic coupling, and burst detection analyses.
    RESULTS: A total of 5020 publications (3768 articles and 1252 reviews) were included. The number of publications increased from 61 in 2000 to 468 in 2024, representing a 7.7-fold growth over this period. The top contributing countries were the United States, Brazil, England, China, and Australia. Eight thematic clusters were identified: urinary incontinence, pelvic pain, bowel dysfunction, conservative management, pelvic floor muscle, pregnancy-related care, exercise interventions, and psychometric evaluation. Co-authorship networks highlighted international collaboration, with prominent institutions in Canada, Australia, and Europe. Co-citation and burst analyses revealed seminal works and emerging topics, with recent trends focusing on women's health, sexual function, pelvic pain, and quality of life.
    CONCLUSIONS: This bibliometric analysis highlights the rapid growth and evolving focus of pelvic floor rehabilitation research over the past 75 years. The findings identify key contributors, international collaborations, and emerging priorities, offering strategic insights for advancing clinical practice and research.
    Keywords:  Bibliometrics; Pelvic floor disorders; Quality of life; Rehabilitation
    DOI:  https://doi.org/10.1007/s00192-025-06243-6
  14. Acta Psychol (Amst). 2025 Jul 17. pii: S0001-6918(25)00619-5. [Epub ahead of print]259 105306
    Non-suicidal self-injury in adolescent depression: A bibliometric study and visualization analysis.
    Pu-Le Liu, Yan Zhang, Jiao Li, Ning Yang, Jing Du, Qiang-Li Dong.
       BACKGROUND: Non-suicidal self-injury (NSSI) is a growing public health concern among adolescents, often co-occurring with depression. Understanding the research landscape in this area is crucial for advancing knowledge and improving interventions.
    AIM: To investigate the current state of research on NSSI in adolescent depression using bibliometric methods, identifying key research hotspots, influential contributors, and emerging trends.
    METHODS: This study analyzed 777 articles published between 2014 and 2024, extracted from the Web of Science Core Collection. VOSviewer and CiteSpace were employed to visualize and analyze the data, focusing on country, journals, authors, citations, and keywords.
    RESULTS: Research output in this field has significantly increased, with China and the United States leading in publications. The Journal of Affective Disorders has emerged as the most influential journal, and You Jianing as the most prolific author. Co-citation and keyword analysis highlighted key areas, including risk factors (e.g., gender, sexual orientation, anxiety, childhood trauma), comorbidities (e.g., borderline personality disorder, neuroticism, sleep disorders, addiction), and reliable assessment tools. Additionally, analysis of co-cited references and keyword evolution indicated that childhood trauma and internet addiction are emerging research frontiers.
    CONCLUSION: This bibliometric analysis provides a comprehensive overview of research on NSSI in adolescent depression, offering valuable insights for understanding current trends, key contributors, and future directions in this critical area of adolescent mental health.
    CORE TIP: This study employs bibliometric analysis to provide a comprehensive overview of research on non-suicidal self-injury in adolescent depression from 2014 to 2024. It identifies key research hotspots, including risk factors like gender, sexual orientation, anxiety, and childhood trauma, as well as comorbidities such as borderline personality disorder and sleep disorders. The analysis highlights the evolving research landscape, with emerging trends focusing on childhood trauma, internet addiction, and reliable assessment tools. This study serves as a valuable resource for researchers seeking to understand the current state of research and identify future directions in this critical area of adolescent mental health.
    Keywords:  Adolescent depression; Bibliometrics; Non-suicidal self-injury; Visualization analysis
    DOI:  https://doi.org/10.1016/j.actpsy.2025.105306
  15. J Thorac Dis. 2025 Jun 30. 17(6): 3498-3515
    Mapping the research trends and hotspots on solid pulmonary nodules from 2000-2024: insights from bibliometric analysis.
    Ke Zhang, Si-Fan Chen, Yun-Dan Zhang, Fa-Jin Lv.
       Background: Due to extensive low-dose computed tomography (CT) screening, the detection rate of solid pulmonary nodules (PNs) is constantly rising. However, existing studies lack a comprehensive understanding of its emerging research trends and interdisciplinary progress, especially in terms of artificial intelligence (AI) integration and molecular characteristics. In this study, we conduct a comprehensive bibliometric analysis to clarify the current research trends and predict future research hotspots in this field, in order to improve diagnostic accuracy, reduce overtreatment, and promote innovation in precise chest oncology.
    Methods: Relevant publications regarding solid PNs were acquired from the Web of Science Core Collection (WoSCC) database [2000-2024]. Scientific landscape of solid PNs was illustrated by quantitatively assessing the scientific output and impact of various academic subjects (i.e., authors, institutions, journal, countries/regions) and qualitatively generating collaboration networks using CiteSpace and Bibliometrix. Lastly, burst detection, clustering analysis and thematic map analysis were implemented to depict shifts in the research frontier of solid PNs.
    Results: Since 2000, a total of 1,413 original articles on pulmonary solid nodules (SNs) have been published. The United States was the leading country in terms of publication volume and centrality in this field. Prof. Kurzrock Razelle from the Medical College of Wisconsin, USA, had the most publications and the highest scientific impact in the field. Clinical Cancer Research published the most manuscripts and had the highest impact in the field. Research institutions from the United States were predominant in the field and several institutions from China were found to have strong influence in the recent years. Current key research foci of solid PNs included tumor size, diagnosis, classification, malignancy, radiomics, segmentectomy, the Response Evaluation Criteria in Solid Tumors (RECIST). Moreover, molecular profile analysis, brain metastases (BMs), lymph node (LN) metastasis, solid lipid nanoparticles (SLNs) and immunotherapy are the emerging research topics.
    Conclusions: The in-depth bibliometric analysis outlines the research landscape in the field of solid PNs, identifying current research trends and hot topics that can guide future research directions. AI-based prediction, diagnosis, and minimally invasive treatment are potential avenues for managing solid PNs.
    Keywords:  Bibliometrix; CiteSpace; Solid pulmonary nodule (solid PN); bibliometric
    DOI:  https://doi.org/10.21037/jtd-24-1669
  16. Obes Surg. 2025 Jul 22.
    Bibliometric and Visual Analysis of Global Trends in Obstructive Sleep Apnea and Bariatric Surgery from 1998 to 2024.
    Zilong Wu, Kaisheng Yuan, Bing Wu, Yun Liu, Sijie Chen, Ruixiang Hu, Cunchuan Wang.
       BACKGROUND: A considerable body of research has established a strong correlation between obstructive sleep apnea (OSA) and bariatric surgery (BS). Despite this, there has been a lack of systematic analysis and visualization of related publications using bibliometric methods.
    METHODS: This research employs bibliometric analysis using the Web of Science Core Collection (WoSCC) to explore the OSA-BS connection from January 1998 to June 2024. Following thorough screening, a total of 1,666 articles were included. Software tools like CiteSpace and VOSviewer were employed to examine the connections among countries, authors, journals, institutions, keywords, and citations.
    RESULTS: The analysis identified the USA leading in research output (732 articles, 43.9% of total) and citations (29,600). Prominent authors include Karmali, Shahzeer, Nico de Vries, and Birch, Daniel W, with Shahzeer contributing 20 articles and accumulating 479 citations. Interdisciplinary collaborations spanned anesthesia, respiratory medicine, and nutrition, with Obesity Surgery emerging as the most prolific journal (318 articles, IF = 2.9/Q1). Keyword co-occurrence analysis revealed core themes: "bariatric surgery" (647 occurrences), "obesity" (477), and "obstructive sleep apnea" (222). Notably, sleep apnea (burst strength: 5.97) and airway management (#2 cluster) dominated recent research, highlighting critical challenges in airway management and respiratory support for individuals with obesity and OSA.
    CONCLUSIONS: The bibliometric analysis highlights the global importance of research on the OSA-BS connection, particularly in anesthesia management and respiratory safety. The findings provide key insights for advancing the field and emphasize the need for further focus on optimizing surgical outcomes and patient safety.
    Keywords:  Bariatric surgery; Bibliometric analysis; Data visualization; Interdisciplinary research; Obstructive sleep apnea
    DOI:  https://doi.org/10.1007/s11695-025-08106-x
  17. Front Oncol. 2025 ;15 1580453
    Trends and emerging frontiers of photodynamic therapy for non-melanoma skin cancer (1979-October 2024): a bibliometric analysis.
    Qi Chen, Mingming Bai, Mingmin Lu, Jingjing Chen, Shanshan Wang, Ping Sun, Linlin Li, Hong Cai.
       Introduction: Photodynamic therapy (PDT) is a non-invasive treatment modality for non-melanoma skin cancer (NMSC). This study aims to use bibliometric analysis to explore the research trends and development in the field of PDT for NMSC, identifying key hotspots and emerging directions.
    Methods: This study conducted a comprehensive literature search in the Web of Science Core Collection database and applied bibliometric analysis and visualization using tools such as VOSviewer, CiteSpace, and the R package "bibliometrix".
    Results: A total of 358 publications were analyzed, with the USA led in contributions and collaborations, with Yale University being the top institution. The Journal of the American Academy of Dermatology made contributions to the field. Prominent authors included Richard L. Edelson, Arthur H. Rook, and Robert S. Stern. The keywords were categorized into four distinct clusters. The keywords were concentrated into four clusters: Treatment methods and targeted conditions, Cellular and immune responses, Clinical applications and therapeutic management and Techniques and research methodologies. Keywords such as "versus host disease" and "extracorporeal photopheresis" continue to emerge prominently in 2024.
    Conclusion: This study provides a comprehensive overview of the distribution patterns and key research hotspots in the field of PDT for NMSC. Future research trends should focus on treatment technologies and immune responses.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; non-melanoma skin cancer; photodynamic therapy
    DOI:  https://doi.org/10.3389/fonc.2025.1580453
  18. Orthop Traumatol Surg Res. 2025 Jul 18. pii: S1877-0568(25)00185-9. [Epub ahead of print] 104336
    Rate and trends of women authorship in a high-impact French orthopaedic journal over 30 years.
    Céline Klein, Alina Badina, Stéphanie Pannier, Patrick Devos, Marie-Christine Plancq, Mathilde Gaumé.
       BACKGROUND: Despite a rise in the number of women in orthopedic surgery over recent decades, their representation in academic and leadership roles remains limited. Authorship in research journals serves as a key indicator of academic involvement. We conducted a retrospective study to assess: (1) the rate of publications by women first and senior authors from 1990 to 2024, and (2) indexed publications and citation impact (3) gender differences in authorship by subspecialty and study type.
    HYPOTHESIS: The authorship gender disparity may no longer persist over the past 30 years in a high-impact French orthopedic journal.
    METHODS: This study analyzed all articles published in Revue de Chirurgie Orthopédique et Réparatrice de l'Appareil Moteur (RCOT) and Orthopaedic and Traumatology Surgery and Research (OTSR) during four periods (1990-1994, 2000-2004, 2010-2014, 2020-2024). The gender of first and senior authors, subspecialties, gender ratios, and their evolution over time were assessed. Indexed publications and citation impact were also reported.
    RESULTS: A total of 3,256 articles were included. Over the 30 years, the proportion of women first and senior authors increased significantly from 15/402 (3.7%) in 1990-1994, to 35/502 (7%) in 2000-2004, 120/950 (12.6%) in 2010-2014, and 306/1,402 (21.8%) in 2020-2024 (p < 0.0001). Specifically, the rate of female first authorship rose from 10/392 (2.5%) to 114/1,210 (13.7%) and senior authorship from 5/367 (1.2%) to 114/1,233 (8.1%) (p < 0.0001). Citation impact improved, with 24 articles reaching the top 10% most cited in the latest period, including 4 in the top 1%. Subspecialty analysis showed increased female authorship across all fields, particularly in paediatrics (+48.4%), hand (+32.5%), elbow (+29.2%), and tumor/infection (+35%) from 2020-2024. Significant increases were observed in most subspecialties (p < 0.05), except knee, shoulder, comment, elbow, and infection.
    DISCUSSION: This study shows a growing female presence in orthopedic publications, with notable subspecialty preferences. Sustaining this trend requires leaders of all genders to mentor and support future candidates. By fostering an inclusive environment that values gender diversity, the field can continue to progress, ensuring equal opportunities for all, regardless of gender, and ultimately enriching the discipline.
    LEVEL OF EVIDENCE: III.
    Keywords:  Authorship; Gender; Journals; Orthopedic surgery; Women
    DOI:  https://doi.org/10.1016/j.otsr.2025.104336
  19. J Alzheimers Dis Rep. 2025 Jan-Dec;9:9 25424823251361056
    Insulin resistance and Alzheimer's disease: Exploring research hotspots and frontiers from a bibliometric and visual analysis (2005-2024).
    Yabin Zhang, Yuting Lv, Tiantian Yang, Qianqian Liu, Qi Guo.
       Background: Alzheimer's disease (AD) and insulin resistance (IR) share intersecting pathological pathways, with IR increasingly implicated in AD pathogenesis. Systematic bibliometric analyses mapping the evolution of this interdisciplinary field remain limited.
    Objective: To quantify global research trends, collaboration networks, knowledge structures, and emerging frontiers in IR-AD research from 2005-2024.
    Methods: We analyzed 2676 publications from the Web of Science Core Collection. Using VOSviewer, CiteSpace, and bibliometrix R package, we conducted quantitative analyses and visualized multiple dimensions including annual publications/citations, countries/regions, institutions, journals, authors, references, and keywords.
    Results: Annual publications grew steadily, peaking at 267 in 2022. The United States dominated productivity (942 papers, 35.2%) and citations (88,170). The University of Kentucky was the top institution (53 papers), while the Journal of Alzheimer's Disease led in output (214 papers) and co-citations (8046). Keyword analysis revealed three clusters: metabolic dysregulation, molecular pathology, and neuroimmune responses. Emerging frontiers highlight neuroimmune mechanisms, with current hotspots focusing on NLRP3 inflammasome activation, gut-brain axis dysregulation, glucose transporter impairment, and therapeutic repurposing of GLP-1 agonists.
    Conclusions: These findings underscore IR-AD as a critical intersection of metabolic and neurodegenerative pathways, advocating for targeted therapies addressing neuroinflammation and cerebral metabolism. By delineating global trends, this study provides a roadmap for future research to bridge translational gaps in AD pathogenesis and treatment.
    Keywords:  Alzheimer's disease; CiteSpace; VOSviewer; bibliometric; bibliometrix R; insulin resistance
    DOI:  https://doi.org/10.1177/25424823251361056
  20. Int J Dev Disabil. 2025 ;71(5): 679-693
    Trends in research related to anxiety disorders on the autism spectrum: a bibliometric study.
    Yerco E Uribe-Bahamonde, Anabel Fernandez-Blanco, Rosario Spencer-Contreras, Osvaldo Hernández-González.
      Anxiety disorder is listed as one of the most common diagnoses for people on the autism spectrum, however to date no bibliometric analysis has been conducted on this literature. This study aimed to analyze, from a bibliometric perspective, the production of scientific research published in Web of Science related to anxiety in the autism spectrum. Since 2013, research has grown exponentially and the most important field turned out to be developmental psychology. The main articles in the field address issues related to parenting, mental health and psychiatric comorbidity. Storch EA, USA, Kings College London (UK), Journal of Autism and Developmental Disorders, were respectively, the most productive author, country, institution and journal in the field. Keyword analysis revealed a close relationship between autism spectrum disorder, anxiety, and depression, making this a novel research field with interdisciplinary practical implications.
    Keywords:  ASD; anxiety; autism; bibliometric analysis; comorbidity; leading authors and journals; mental health; neurodevelopmental disorders
    DOI:  https://doi.org/10.1080/20473869.2023.2283649
  21. Hepat Med. 2025 ;17 39-59
    Historical and Emerging Trends in Hepatitis B Virus Integration: A Bibliometric Visual Analysis.
    Jia Liu, Longhai Xu, Xuefeng Ma, Yanzhen Bi, Yongning Xin.
       Purpose: Hepatitis B virus (HBV) infection is a global health concern, linked to chronic hepatitis, cirrhosis, and hepatocellular carcinoma. HBV genome integration into host DNA is critical in disease progression and oncogenesis. Despite advancements in understanding HBV pathogenesis and therapies, the mechanisms and implications of HBV integration remain unclear. This study employs bibliometric analysis to evaluate research trends and collaborations in HBV integration.
    Materials and Methods: We utilized the Web of Science Core Collection (WOSCC) as our primary data source, meticulously screening and identifying 972 pertinent articles published between 1980 and November 30, 2024. Bibliometric tools, including VOSviewer, CiteSpace, and Bibliometrix, were employed to analyze publication trends, authorship, institutional contributions, and key research areas. Citation data and keyword clusters were examined to identify research hotspots.
    Results: Publications have steadily increased from 1980 to November 30, 2024, with China and the United States contributing the most studies. While China leads in publication volume, the United States has the highest citation impact. The Institut Pasteur in Paris ranks highest in publications. Hino O is the most prolific author, and Koike K the most cited. Hepatology is the most cited journal, and the article "Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma" is the most referenced. Cluster analysis revealed five major research themes.
    Conclusion: This study highlights global research trends and key contributors in HBV integration, offering insights into current hotspots and future directions. The findings provide a basis for advancing diagnostic and therapeutic strategies targeting HBV integration.
    Keywords:  bibliometrics; genomic instability; hepatitis B virus; integration; visualization
    DOI:  https://doi.org/10.2147/HMER.S526977
  22. Curr Neuropharmacol. 2025 Jul 21.
    Resilience and Recalibration of Bibliometric Indicators in Neurosciences and Neuropharmacology Journals After COVID-19: A Longitudinal Rate of Change Analysis Using Mixed-Effects Models.
    Camilo Rios-Castañeda, Heriberto Aguirre-Meneses, Marco-Antonio Nuñez-Gaona, Ernesto Roldan-Valadez.
       INTRODUCTION: The COVID-19 pandemic triggered unprecedented changes in the scholarly publishing landscape, particularly in biomedical fields such as Neurosciences and Neuropharmacology. Several journals experienced steep, short-term increases in citation metrics during 2020-2022. However, it remains uncertain whether these surges reflected a sustainable impact or temporary inflation. This study aimed to analyze post-pandemic bibliometric behavior by evaluating the Rate of Change (RoC) in key journal-level indicators from 2013 to 2023.
    METHODS: A retrospective longitudinal study was conducted on 233 neuroscience journals indexed in the Journal Citation Reports. Six indicators were analyzed: Journal Impact Factor (JIF), Eigenfactor Score, Immediacy Index, Article Influence Score, Cited Half-Life, and Total Citations. RoC was calculated for each metric on an annual basis. Mixed-effects models with random intercepts and slopes were constructed to evaluate longitudinal trajectories and identify changes associated with three defined periods: prepandemic (2013-2019), pandemic (2020-2022), and post-pandemic (2023). Subgroup analyses assessed journal quartiles and categories to explore variations in impact resilience.
    RESULTS: The pandemic period (2020-2022) showed significant increases in RoC for JIF (mean β = +4.85, p = 0.004), Immediacy Index (β = +6.22, p = 0.002), and Total Citations (β = +5.88, p < 0.001). These changes were more prominent in top-quartile journals and those classified under Neuropharmacology. In contrast, alternative metrics such as the Eigenfactor Score and Article Influence Score remained relatively stable across the same period. In 2023, most indicators exhibited a normalization trend, with JIF and Immediacy Index showing marked deceleration in RoC, suggesting a post-pandemic recalibration. Journals with sustained positive trajectories were primarily concentrated in high-impact clusters, with Current Neuropharmacology ranking among the top performers by RoC slope.
    DISCUSSION: The findings demonstrate that the surge in citations during the pandemic was primarily transitory and varied across bibliometric indicators. Traditional metrics like JIF and Immediacy Index were more sensitive to systemic shocks, while influence-based indicators (Eigenfactor and Article Influence Score) showed higher temporal resilience. The application of RoC allowed for a nuanced interpretation of metric trajectories and minimized misinterpretation of short-term spikes. Limitations include reliance on publicly available data and potential lag effects in citation behavior not fully captured within the 10-year window.
    CONCLUSION: This study reveals that pandemic-era citation inflation in Neuroscience journals was largely temporary and metric-dependent. RoC-based modeling offers a reproducible and adaptable approach for assessing the sustainability of bibliometric trends. These insights can help editors, funders, and academic institutions better understand journal performance, make informed decisions about research dissemination, and refine metrics-based evaluation frameworks in the post-pandemic publishing environment.
    Keywords:  Bibliometrics; COVID-19 pandemic; citation analysis; impact factor.; longitudinal studies; neuropharmacology; neurosciences; scholarly publishing
    DOI:  https://doi.org/10.2174/011570159X384613250702110845
  23. Digit Health. 2025 Jan-Dec;11:11 20552076251362098
    Emerging trends in Alzheimer's disease diagnosis and prediction using artificial intelligence: A bibliometric analysis of the top cited 100 articles.
    Guangheng Zhang, Weijie Zhao, Shimeng Lv, Ziyue Wang, Yunhao Yi, Haoteng Ma, Yitong Lu, Wei Yan, Jing Teng.
       Background: AD is a significant public health challenge, and AI technologies, including deep learning and machine learning, offer the potential to dramatically improve diagnostic and predictive accuracy. These technologies are widely applied in AD research. However, comprehensive literature summaries of this field remain limited. This study uses bibliometric analysis to examine research hotspots, trends, future development potential, and limitations in AI-based AD diagnosis and prediction.
    Methods: We conducted a bibliometric analysis of 100 top cited studies on AI-based diagnosis and prediction of AD, using data from the WoSCC. We performed the analysis using CiteSpace 6.3.R2, VOSviewer 1.6.19, Scimago Graphica 1.0.39, Microsoft Excel 2021, and R package Bibliometrix running in RStudio, visualizing the results through graphical representations.
    Results: It was found that the top cited 100 articles came from 51 journals and 31 countries. The journal with both the highest number of published articles and the greatest citation frequency was NEUROIMAGE, while PROTEIN ENGINEERING DESIGN & SELECTION boasted the highest average citation rate. The country with the largest volume of published articles was the United States, followed by China and the United Kingdom. In terms of institutions, the University of North Carolina had produced the most publications. The keywords identified fall into 9 categories. The most frequently occurring keywords are "Alzheimers disease", "mild cognitive impairment", "classification", "MRI", "deep learning", "diagnosis", "dementia", "biomarkers", "brain atrophy", "machine learning", "voxel based morphometry", "prediction", and "patterns".
    Conclusion: AI-based technologies for AD diagnosis and prediction are becoming indispensable clinical tools. Future research should leverage AI to identify novel AD biomarkers, enabling precision diagnosis and treatment. However, our bibliometric analysis has limitations: language and citation biases may skew interpretation of emerging AI-AD trends.
    Keywords:  Alzheimer's disease; Artificial intelligence; bibliometric analysis; diagnosis; prediction
    DOI:  https://doi.org/10.1177/20552076251362098
  24. Clin Ophthalmol. 2025 ;19 2305-2324
    Oxidative Stress in Dry Eye Disease: A Bibliometric Analysis.
    Yifan Lei, Xin Yun Huang, Haodong Guo, Rongqing Huang, Yajun Shi, Jue Hong, Yanting Yang, Xiaopeng Ma.
       Purpose: To study the knowledge structure and evolution of oxidative stress in dry eye disease (DED) using bibliometrics and explore prospective anti-oxidative stress strategies for future clinical interventions.
    Methods: The Web of Science Core Collection (WoSCC) was used as the data source to systematically retrieve and screen the research literature published between January 1, 1992, and December 31, 2024, related to oxidative stress research in DED. The data were then analyzed using VOSviewer, CiteSpace, and R package Bibliometrix to visualize the network of countries, organizations, journals, authors, and keywords related to oxidative stress in DED.
    Results: A total of 491 publications were identified over a 30-year period from 1995 to 2024. There is a general upward trend in annual publications. The most prolific countries, institutions, journals and authors were China, KEIO UNIV, INVEST OPHTH VIS SCI, and TSUBOTA K, respectively. The keywords in this research field mainly focused on inflammation, ocular surface, antioxidants, lacrimal glands, cornea, reactive oxygen species. "Ferroptosis", "nanoparticles", "diabetic retinopathy", "autophagy", "meibomian glands", and "NLRP3 inflammasome" are emerging research hotspots in recent years.
    Conclusion: This study provides the first bibliometric approach to hot topics and emerging trends in the field of oxidative stress in DED. "Ferroptosis", "nanoparticles", "autophagy", "NLRP3 inflammasome", and so on are emerging directions being investigated in the field. Antioxidants in nanocarriers show promising applications. Clinical translation and international cooperation are the keys to future breakthroughs. Interdisciplinary collaboration should be strengthened to promote precision medicine and innovative therapy development.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; dry eye disease; oxidative stress
    DOI:  https://doi.org/10.2147/OPTH.S532001
  25. Medicine (Baltimore). 2025 Jul 18. 104(29): e43088
    Research hotspots and current status of iliotibial band studies: A bibliometric analysis (1934-2023).
    Fei He, Yiyi Chen, Siliang Zeng, Yi Huang, Bo Yu, Wenhua Chen, Yu Liu, Jianqiang Lu.
       BACKGROUND: The iliotibial band (ITB), a unique musculoskeletal structure, is gaining interest in various fields such as biomechanics, orthopedics, sports medicine, and rehabilitation medicine. The pathogenesis, prevention, and treatment of ITB-related diseases are controversial. Despite an increasing number of studies, there is a lack of organized literature sorting and hotspot analysis. This study aims to comprehensively analyze publications related to the ITB and summarize the research focal points and current state in this domain.
    METHODS: Literature characteristics were extracted from the Web of Science Core Collection (WoSCC) database from inception to January 17, 2023. Quantitative and qualitative analyses were performed, and the data were visualized using Microsoft Excel, CiteSpace, VOSviewer, and Tableau software.
    RESULTS: A total of 1230 relevant articles were identified, with the majority from the United States (594 articles). Most articles were published in 2018, and the article with the highest number of citations (1013) was published in 2002. The American Journal of Sports Medicine had the most articles. Harvard University and Andrew Amis were the most prolific institution and author, respectively. Research hotspots identified through citation and keyword analysis included knee, anterior cruciate ligament, anatomy, iliotibial band syndrome, anterolateral ligament, injuries, and biomechanics.
    CONCLUSION: This study provides a comprehensive summary of the research hotspots and current status of ITB research, offering a fresh perspective for scholars to gain a deeper understanding. The findings suggest additional research directions relevant to this subject in the future.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; hotspots; iliotibial band; visualization
    DOI:  https://doi.org/10.1097/MD.0000000000043088
  26. Front Med (Lausanne). 2025 ;12 1559099
    Trends and hotspots in cupping therapy research for pain: a bibliometric study.
    Renjie Xu, Shi-Lu Liu, Guangxu Xu, Chengjie Yan, Qi Cui, Shan Liu, Mingliang Sun.
       Background: Cupping therapy (CT), a traditional form of alternative medicine, has gained attention as a non-pharmacological intervention for pain. Its applications span various pain-related conditions such as musculoskeletal disorders, migraines. Despite its growing popularity, comprehensive analyses of research trends, collaboration networks, and emerging hotspots in CT for pain remain limited.
    Methods: This bibliometric study analyzed 234 publications on CT for pain sourced from the Web of Science Core Collection. CiteSpace and VOSviewer software, and Bibliometric analysis website were employed to analyze trends, identify key contributors, and map global collaboration networks. Co-cited references, keyword clustering, and burst detection analyses were performed to uncover research hotspots and trends.
    Results: A total of 234 publications from 31 countries and 437 institutions were included. China led in publication volume, while the United States had the highest total citations. The Korea Institute of Oriental Medicine and the University of Duisburg-Essen were identified as central hubs for institutional collaboration. High-frequency keywords such as "pain," "cupping therapy," "acupuncture," and "negative pressure" highlighted a focus on CT's clinical applications and mechanisms. Emerging trends included the integration of CT with modalities like acupuncture and physical therapy. However, methodological limitations, such as inconsistent protocols and insufficient mechanistic studies, were identified as key challenges.
    Conclusion: This study offers an overview of the research landscape for CT in pain management, its potential as a safe and effective therapy. To strengthen its role in evidence-based medicine, future research should focus on standardizing treatment protocols, conducting high-quality clinical trials, and exploring its underlying mechanisms.
    Keywords:  CiteSpace; VOSviewer; bibliometric; cupping therapy; pain; visualization analysis
    DOI:  https://doi.org/10.3389/fmed.2025.1559099
  27. Front Oncol. 2025 ;15 1588735
    Global research trends and hotspots in prognostic prediction models for pancreatic cancer: a bibliometric analysis.
    Siyuan Ouyang, Jing Zhang, Fuyao Liu, Qi Jiang, Wei Xing, Jie Chen, Jinggang Zhang.
       Background: Pancreatic cancer is a highly aggressive malignancy of the digestive system, characterized by insidious onset and rapid progression. Most cases are diagnosed at advanced stages, complicating surgical resection and presenting significant challenges for clinical treatment. Recent advancements have emphasized individualized treatment strategies tailored to patients' specific conditions. Consequently, accurate preoperative assessment is crucial, highlighting the urgent need to develop more reliable predictive models to guide personalized treatment plans.
    Methods: A systematic literature search was conducted using Web of Science Core Collection (WoSCC) database, covering publications from January 1, 1995, to October 25, 2024. A comprehensive bibliometric analysis was performed employing analytical tools such as VOSviewer, CiteSpace and Microsoft Excel.
    Results: This study includes 919 publications authored by 6716 researchers from 3727 institutions in 222 countries and regions. The articles were published in 301 journals, with 1,640 distinct keywords and 25,910 references. China led in publication volume, while the United States garnered the most citations. The top three research institutions in this field were Fudan University, Shanghai Jiao Tong University, and Sun Yat-sen University. Yu Xianjun from Fudan University emerged as the most prolific author with the highest citation count. Frontiers in Oncology had the highest publication volume, while the Annals of Surgery received the most citations. Medical imaging, biochemistry, immunology, bioinformatics, genetics, and interdisciplinary integrative research are the main research disciplines in the field of prognosis prediction for pancreatic cancer. The results of keyword co-occurrence and literature co-citation analysis revealed emerging hotspots and trends in this field, including CA19-9, CT, inflammation, machine learning, tumor microenvironment, radiomics, genes, nomograms, randomized controlled trials, long-term survival, and metastasis.
    Conclusion: This bibliometric analysis provides an overview of research conducted over the past three decades, offering insights into the current state of knowledge and outlining directions for future studies on prognosis prediction models for pancreatic cancer. Biochemical indicators have consistently emerged as key research focal points. The tumor microenvironment represents a currently popular research direction, while bioinformatics, medical imaging, and artificial intelligence are gaining traction as future trends in this field. In the future, prognostic models for pancreatic cancer require further refinement to ensure reliable guidance for therapeutic decision-making.
    Keywords:  bibliometrics; pancreatic cancer; prediction model; prognosis; trends
    DOI:  https://doi.org/10.3389/fonc.2025.1588735
  28. Front Oncol. 2025 ;15 1594848
    A bibliometric analysis of liver cancer bone metastases: advances in mechanisms of occurrence and treatment options.
    Jiyong Wei, Yanni Lan, Guipeng Lan, Ronghe Gu.
       Background: Liver cancer ranks as the sixth most frequently diagnosed cancer and is the third leading cause of cancer-related deaths worldwide. Its poor prognosis is mainly due to tumor metastasis. Bone metastasis commonly occurs in the advanced stages of liver cancer and can significantly impact patients' quality of life and prognosis. However, current treatment methods for bone metastasis resulting from liver cancer have significant limitations. This article aims to review the latest research and trends in global studies on bone metastasis associated with liver cancer.
    Methods: This study used the Web of Science Core Collection to gather 3,347 articles on liver cancer with bone metastasis published from 2004 to 2024.The study applied bibliometric analysis methods, including CiteSpace, VOSviewer, and other tools, to examine countries, institutions, journal authors, keywords, and references.
    Results: From 2004 to 2024, we collected 3,845 records, including 3,347 articles and 498 reviews from 92 countries. Publications had shown exponential growth, peaking in 2021 with an annual growth rate of 8.3%. The research involved 13,188 organizations. China had the most publications (n=970, 29%), followed by the United States (n=648, 19.4%), Japan (n=317, 9.5%), and Germany (n=228, 6.8%); Canada had a notably higher rate of international collaboration at 44.8%. In total, 830 journals contributed to this research. The most cited journal was "J Clinical Oncol" with 4,275 citations, while "New Engl J Med" had the highest impact factor at 158.5. The research involved 23,710 authors, with Wang, Xin and Zhang, Chao being the authors with the most publications. Wang Z published the first study on this topic in 2007. In 2008, Zhang Y, Wang Y, and Zhang J also began researching this area and have continued to be actively involved since then. The study referenced a total of 79,935 sources, with the paper by Sung H et al., published in CA Cancer J Clin in 2021, achieving the highest citation rate of 42.46.
    Conclusion: This study systematically summarizes research findings on liver cancer with bone metastasis from 2004 to 2024, It also identifies and predicts global research hotspots and trends. In the future, the molecular mechanisms of liver cancer with bone metastasis will be a major research topic. The expansion of surgical treatment options and the advancement of innovative therapies will benefit more patients.
    Keywords:  bibliometric; bone metastasis; liver cancer; molecular; resection
    DOI:  https://doi.org/10.3389/fonc.2025.1594848
  29. Fungal Biol. 2025 Aug;pii: S1878-6146(25)00064-9. [Epub ahead of print]129(5): 101598
    Overview of scientific productivity in the field of fungal stress research.
    Alene Alder-Rangel, Drauzio E N Rangel.
      The study of fungal stress (FS) responses contributes to a deeper understanding of this important group of organisms. This bibliometric study explores what research has been conducted on how agricultural, environmental, and industrial important fungi respond to changes or stress in their environment. The Web of Science was employed to find publications related to FS tolerance, and after sorting, 3126 articles were analyzed. The major fungus/fungi studied in each article were noted and sorted into categories of Environmental, Industrial, or Agricultural FS. The publications were then assigned into these categories or General, for articles covering many fungi. Agricultural Fungi were further divided into Plant-pathogenic, Insect-pathogenic, Antagonist, Postharvest decay, and Nematode-trapping niches. Seventy years of research into FS were found, with the majority of publications after 1990, peaking in 2022. Almost half of the FS publications were about Agriculture, and plant pathogens were the most common niche studied. The most studied fungi were Beauveria bassiana, Saccharomyces cerevisiae, and Aspergillus nidulans. Studies on FS were conducted in 87 countries by at least 9766 researchers. Most of the top institutions and researchers in FS publications are Chinese.
    Keywords:  Bibliometric analysis; Fungal stress responses; International Symposium on Fungal Stress – ISFUS; Scientometrics; Web of Science
    DOI:  https://doi.org/10.1016/j.funbio.2025.101598
  30. Front Oncol. 2025 ;15 1556521
    Progress and current trends in prediction models for the occurrence and prognosis of cancer and cancer-related complications: a bibliometric and visualization analysis.
    Siyu Li, Wenrui Li, Xiaoxiao Wang, Wanyi Chen.
       Objective: Prediction models, which estimate disease or outcome probabilities, are widely used in cancer research. This study aims to identify hotspots and future directions of cancer-related prediction models using bibliometrics.
    Methods: A comprehensive literature search was conducted in the Science Citation Index Expanded (SCIE) from the Web of Science Core Collection (WoSCC) up to November 15, 2024, focusing on cancer-related prediction models research. Co-occurrence analyses of countries, institutions, authors, journals, and keywords were conducted using VOSviewer 1.6.20. Additionally, keyword clustering, timeline visualization, and burst term analysis were performed with CiteSpace 6.3.
    Results: A total of 1,661 records were retrieved from the SCIE. After deduplication and eligibility screening, 1,556 publications were included in the analysis. The bibliometric analysis revealed a consistent annual increase in cancer-related prediction model research, with China and the United States emerging as the leading contributors. The United States, England, and the Netherlands had the strongest collaborative networks. The most frequent keywords, excluding "prediction model" and "predictive model", included nomogram (frequency=192), survival (191), risk (121), prognosis (112), breast cancer (103), carcinoma (93), validation (87), surgery (85), diagnosis (83), chemotherapy (80), and machine learning (77). Besides, the timeline view analysis indicated that the "#7 machine learning" cluster was experiencing vigorous growth.
    Conclusion: Cancer-related prediction models are rapidly advancing, especially in prognostic models. Emerging modeling techniques, such as neural networks and deep learning algorithms, are likely to play a pivotal role in current and future cancer-related prediction model research. Systematic reviews of cancer-related predictive models, which could help clinicians select the optimal model for specific clinical conditions may emerge as potential research directions in this field.
    Keywords:  bibliometrics; cancer; hotspots and trends; machine learning; prediction models; visualization analysis
    DOI:  https://doi.org/10.3389/fonc.2025.1556521
  31. Work. 2025 Jul 23. 10519815251353460
    Two decades of research in occupational physical activity for health: A bibliometric analysis.
    Xinxin Sheng, Kai Li, Tianwei Li, Zhen Yang, Xingyi Yang, Sitong Chen.
      BackgroundThere is a paradox in the field of physical activity, where leisure-time physical activity and occupational physical activity have inconsistent associations with health outcomes. Therefore, an increasing number of studies have investigated the associations between occupational physical activity and health outcomes. Given the rapid growth of publications in the field, an analytical synthesis of the literature is needed.ObjectiveThe aim of this bibliometric analysis was to assess scientific productivity and provide a knowledge structure for the field of occupational physical activity and health from 2004 to 2024.MethodsEligible publications records indexed on the Web of Science were downloaded for conducting a performance analysis, science mapping and visualisation. The VOSviewer, CiteSpace, and Microsoft Excel were used to conduct the bibliometric analysis.ResultsDuring the past two decades, a total of 1619 publications in the field of occupational physical activity for health were included. Healy G.N. and Dunstan D.W. were the most published authors in this field (41 publications). The USA (415 publications) and the University of Queensland (88 publications) were the most published countries and research institutions. The knowledge structure in this field showed a path of evolution from observational to intervention studies. Human resource management and organisational behaviour would be future research topics.ConclusionsResults of this bibliometric analysis provide researchers and other stakeholders with a comprehensive knowledge structure in the field of occupational physical activity for health and evidence-based recommendations for future research.
    Keywords:  bibliometrics; exercise; occupational health; public health; sedentary behaviour; work
    DOI:  https://doi.org/10.1177/10519815251353460
  32. Front Nutr. 2025 ;12 1613395
    Global Leadership Initiative on Malnutrition: a bibliometric analysis of research trends and contributions (2018-2024).
    Qimeng Xu, Qiufu Li, Yucheng Yao, Ying He, Sitao Tan, Xiaoxia Liu, Xiaoyu Chen.
       Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria were officially introduced in 2018 with the aim of establishing a standardized global framework for the diagnosis of malnutrition. Synthesizing expert consensus from multiple international organizations, the GLIM criteria proposed a two-step diagnostic model integrating both phenotypic and etiologic components. Although GLIM-related research has expanded rapidly in recent years, a comprehensive bibliometric evaluation remains absent.
    Methods: Relevant literature published between 2018 and 2024 was retrieved from the Scopus database. Only English-language original research articles and reviews were included. A total of 729 eligible publications were analyzed using VOSviewer (v1.6.10), CiteSpace (v5.8.R3), and the online platform Bioinformatics. The analysis covered various dimensions, including countries, institutions, authors, journals, keywords, and highly cited references.
    Results: The volume of GLIM-related publications has shown a steady upward trajectory, peaking in 2024. China emerged as the most prolific country, followed by Spain and Japan. The top contributing institutions included Uppsala University, Capital Medical University, and Beijing Shijitan Hospital. Among the most productive authors were Cederholm T, Shi H, and Correia MITD. Clinical Nutrition and Nutrients were identified as the core journals in this field. Keyword analysis revealed that "malnutrition," "diagnosis," "sarcopenia," "cancer," and "nutritional risk" were pre-dominant themes, while "systematic review," "protein blood level," and "gastric cancer" represented emerging areas of interest.
    Conclusion: This study represents the first comprehensive bibliometric analysis of research related to the GLIM criteria. It identifies key contributors, collaboration networks, and thematic evolutions in the field, highlighting a transition from the development of diagnostic frameworks to clinical application and individualized nutritional assessment. These findings provide a valuable reference for guiding future research directions in GLIM-related domains.
    Keywords:  GLIM criteria; bibliometric analysis; clinical application; malnutrition; nutritional assessment; sarcopenia
    DOI:  https://doi.org/10.3389/fnut.2025.1613395
  33. Front Immunol. 2025 ;16 1607240
    Hydrogels in cancer treatment: mapping the future of precision drug delivery.
    Xiang Liu, Qiang Zhou, Yue Yang, Xin Wu, Jie Chen, Ruoqin Wang, Erhua Chen.
       Background: Current primary tumor treatments include curative resection, chemotherapy, and radiotherapy. However, these conventional methods lack precise drug delivery. Hydrogels, adaptable to the biological characteristics of different tumors, offer potential as drug delivery systems and represent a significant area of research in tumor treatment. In this study, we aimed to conduct a bibliometric analysis to reveal the current progress and future prospects of hydrogels for drug delivery in cancer.
    Methods: Publications concerning hydrogels in tumor drug delivery were retrieved from the Web of Science Core Collection (WoSCC) database. Data regarding countries/regions, institutions, journals, authors, and document types were collected. Bibliometric analysis and network visualization were performed using CiteSpace, HisCite, VOSviewer, Alluvial Generator, and R software.
    Results: China, the United States, and India were the leading contributing countries. Of the 98 relevant categories, 94 experienced citation bursts between 2000 and 2024. The research team led by Professor Pourmadadi Mehrab demonstrated substantial influence in this field. The International Journal of Biological Macromolecules was the most prolific journal. The top three emergent categories originated in 2020 or later, are "Chemistry, Applied", "Engineering, Environmental", and "Biochemistry & Molecular Biology". "Designing hydrogels for controlled drug delivery" was the most highly cited article. Recent emergent keywords included immunotherapy, immunogenic cell death, carboxymethyl cellulose, and antibacterial. Key concept alluvial flow visualization revealed six terms: peritoneal carcinomatosis, iron oxide nanoparticles, drug delivery, release kinetics, carbon dots, and pathway. Nano-composite hydrogels, immunotherapy, quercetin, pancreatic cancer, and oral cancer exhibited recent activity within the cited article timeline, suggesting these areas as potential future research hotspots.
    Conclusion: This bibliometric analysis identifies future research directions within the developing field of hydrogels for drug delivery in cancer. This study provides recommendations and directions for the development of hydrogels as tumor drug delivery systems.
    Keywords:  CiteSpace; bibliometrics; cancer; drug delivery; hydrogels
    DOI:  https://doi.org/10.3389/fimmu.2025.1607240
  34. Obes Surg. 2025 Jul 18.
    Sexual Health in Bariatric Surgery: A Bibliometric Study.
    Pınar Tunç Tuna, Esra Uslu.
       BACKGROUND: Bariatric surgery not only treats obesity-related diseases but also positively impacts sexual health. However, research in this field is limited. Analyzing the overall status of the literature is essential to guide researchers. This study aims to bibliometrically examine publications on bariatric surgery and sexual health.
    METHODS: The study was conducted using publications on bariatric surgery and sexual health in the WoS database (N = 217). The Web of Science database was searched on June 19, 2025, using a topic, which includes the title, abstract, author keywords, and keyword plus fields. Data were used the keywords ("Obesity surgery" OR "bariatric surgery") AND ("sexual life" OR "sexuality" OR "sexual health" OR "sexual problems" OR "sexual function" OR "sexual dysfunction") without time restrictions. Analyses were performed using R (R 4.2.2.), and results were presented under basic information, treemap, trend topics, and thematic map.
    RESULTS: A total of 217 publications from 1996 to 2025 were analyzed. The average publication age was 7.66 years. The United States had the most publications, and bariatric Surgery was the leading journal in the field. Although the annual number of publications has fluctuated, the highest number of publications was reached between the years 2017 and 2019. Treemap analysis highlighted weight loss (n = 26, 6%), quality of life (n = 24, 6%), and erectile dysfunction (n = 12, 3%) as prominent keywords. The topics that have been on the agenda for the last 2 years are "infertility, overweight." "Pregnancy" and "contraception" are themes that continue to develop, "erectile dysfunction" is a theme that drives the field, while "quality of life" is a well developed but isolated topic.
    CONCLUSIONS: The topic of sexual health in the field of bariatric surgery is rapidly growing despite its relative novelty. Quality of life and body reconstruction topics constitute a limited portion of the literature. However, research is largely focused on male sexual problems, while studies on women are mostly shaped around the axis of pregnancy. This highlights the need for research specifically addressing women's sexual health.
    Keywords:  Bariatric surgery; Bibliometric analysis; Sexuality
    DOI:  https://doi.org/10.1007/s11695-025-08090-2
  35. J Orthop. 2025 Jul;65 324-328
    Tibial shaft fractures: A bibliometric analysis of the top 50 most cited publications.
    Ethan Gilkinson, Ben Murphy, Niall McGoldrick, John Quinlan.
       Background: Tibial shaft fractures (TSFs) are a frequent presentation within orthopaedics, most often occurring in young males following a high energy trauma. The appropriate management of these fractures is crucial, ensuring patients have the best chance at achieving a functional recovery. In spite of the vast number of studies conducted on TSFs, the quality of scientific evidence and various trends related to this injury remains poor. The aim of our analysis is to identify these trends within the 50 most cited publications pertaining to TSFs.
    Methods: A bibliometric analysis was carried out using the Web of Science platform to report the 50 most cited publications associated with TSFs. The publications were screened using definite inclusion and exclusion criteria. Features such as institution, authorship, level of evidence and patient demographics were reported.
    Results: The 50 most cited publications in total listed 10, 407 citations, with the most cited study receiving 1075 citations. Treatment outcomes (66 %) and surgical technique (32 %) were the primary focus of the majority of the publications. Retrospective cohort and case control studies made up almost half of the studies (48 %), many being of level III evidence. The McMaster University Hospital was the institution that produced the greatest number of studies, with the Journal of Bone and Joint Surgery having published most of the articles.
    Conclusion: Many publications exist related to TSFs, primarily focusing on treatment outcomes and how to minimize the incidence of non-union following surgical fixation. However, a significant number of the publications were of low evidence and were identified as being retrospective in nature. Following this analysis, future research should aim to produce studies of a higher quality and focus on areas that carry the most promise or influence, such as the use of recombinant human bone morphogenetic protein-2 in intramedullary nailing of TSFs.
    Keywords:  Bibliometric analysis; Tibial shaft fractures; Treatment outcomes
    DOI:  https://doi.org/10.1016/j.jor.2025.06.020
  36. Discov Oncol. 2025 Jul 21. 16(1): 1380
    Research trends between acquired immune deficiency syndrome and hematological malignancies: a bibliometric analysis.
    Qiwen Zhou, Hao Sun, Shanshan Fan, Lan Luo, Jianhua Ji, Zejiao Jiang, Haiyan Min.
       OBJECTIVE: This study examines the well-documented association between HIV/AIDS and hematological malignancies, where HIV infection increases the risk of developing these conditions, using bibliometric analysis to explore research trends and global patterns.
    METHODS: A bibliometric analysis was performed using the Web of Science Core Collection database, focusing on English-language articles related to "HIV/AIDS" and "hematological malignancies" published from 1979 to August 2024, employing VOSviewer, CiteSpace, and R package "Bibliometrix" for data analysis and visualization.
    RESULTS: A total of 1336 relevant articles were identified, with the United States as the leading contributor, followed by China. Prominent research institutions included the Université Paris Cité, publique hopitaux paris (APHP) and Harvard University. Blood is the most influential journal in this field, while authors Elie Azoulay and Hans-Peter Kiem were noted as influential figures. Keyword analysis highlighted bone marrow transplantation, lymphoma, and epidemiology as key research areas.
    CONCLUSION: This study analyzed the evolving research landscape, hotspots, and trends in HIV/AIDS and hematological malignancies. Our findings reveal a critical shift from managing acute infections to focusing on long-term clinical outcomes, highlighting the paramount importance of continued emphasis on precise diagnostics, personalized treatment strategies, and optimized interventions like bone marrow transplantation to improve patient prognosis and survival.
    Keywords:  Bibliometric analysis; HIV/AIDS; Hematological malignancies; Research trends
    DOI:  https://doi.org/10.1007/s12672-025-03228-1
  37. Int J Chron Obstruct Pulmon Dis. 2025 ;20 2393-2408
    Acupuncture for Chronic Obstructive Pulmonary Disease: A 38-Year Bibliometric Landscape of Global Research Trends and Knowledge Evolution (1986-2024).
    Kaiting Wu, Chen Ruan.
       Background: Despite growing interest in acupuncture as a complementary therapy for chronic obstructive pulmonary disease (COPD), comprehensive analyses of its global research trajectory, disciplinary convergence patterns, and geopolitical contributions remain unexplored. This study addresses this gap by mapping the intellectual and geopolitical architecture of acupuncture-COPD research over nearly four decades, a period chosen to capture the significant developments in acupuncture's global recognition since the late 1980s, when traditional medicine began to gain more global attention.
    Methods: We conducted a longitudinal bibliometric analysis of 299 publications indexed in the Web of Science Core Collection (1986-2024). Employing Bradford's and Lotka's laws, co-citation networks, and keyword co-occurrence clustering, we systematically evaluated temporal productivity trends, institutional/country contributions, citation dynamics, and thematic evolution using SciMAT, VOSviewer, and bibliometrix R-package. (Response to Editor's Comment 1).
    Results: Research productivity followed a triphasic trajectory: a dormant phase (1986-2000, ≤2 articles/year), a stabilization phase (2001-2014, +4% annual growth), and an exponential growth phase (2015-2024, 13 articles/year), closely aligned with global policy shifts in traditional medicine. China emerged as the dominant contributor (338 articles, 64.2% global output), yet Canada demonstrated superior research impact (108 citations/article), highlighting a productivity-impact paradox. Mechanistic investigations into neuroimmunological pathways, particularly μ-opioid receptor modulation (centrality 0.74), became central research pillars, reinforced by biomarker-correlated clinical trials showing β-endorphin-FEV1 interactions (r = 0.526, p = 0.008). Persistent translational gaps were evident, with 63% of RCTs relying on subjective "deqi" assessments despite technological advances in objective acupuncture monitoring.
    Conclusion: This analysis reveals critical asymmetries between Eastern research productivity and Western methodological innovation in acupuncture-COPD research. This analysis suggests a need for a threefold strategy integrating multiscale neuroimaging validation, globalized trial standardization through CONSORT-Acupuncture frameworks, and equitable North-South knowledge exchange to address the growing burden of COPD-related dyspnea in aging populations.
    Keywords:  COPD; acupuncture; bibliometrics; neuroimmunology; research disparities; traditional medicine
    DOI:  https://doi.org/10.2147/COPD.S531611
  38. SAGE Open Nurs. 2025 Jan-Dec;11:11 23779608251361012
    A Comparison of OpenAlex With Scopus and Web of Science for Tracking Scholarly Nursing Literature.
    Belén Mezquita, Leandra Martín-Delgado, Laia Wennberg-Capellades, Ángel Borrego.
       Background: Researchers have traditionally used commercial databases such as Scopus and Web of Science to track scholarly literature and ascertain the impact of publications in terms of citations. In recent years, new open data sources, such as OpenAlex, have appeared, which broaden the array of tools accessible for exploring academic literature.
    Objective: This study compares the coverage of scholarly nursing literature by OpenAlex, Scopus, and Web of Science in terms of journals, articles, and citations indexed.
    Methods: A list of nursing journals indexed by OpenAlex, Scopus, and Web of Science was compiled to compare the titles covered in terms of country of publication, publisher, and open access availability. Citations of nursing articles published between 2000 and 2022 in the three sources were also analyzed.
    Results: OpenAlex indexes nearly all the journals covered by Scopus and Web of Science, plus additional sources from countries outside the Western world. In terms of individual articles, OpenAlex indexes more citations than Scopus and Web of Science.
    Conclusion: OpenAlex is a comprehensive source for tracking nursing literature. Currently, its main limitation lies in the lack of a user-friendly web interface, as the need to use an API for data retrieval can complicate the search process for end users.
    Keywords:  bibliometrics; citation analysis; databases
    DOI:  https://doi.org/10.1177/23779608251361012
  39. Front Neurosci. 2025 ;19 1636904
    Bibliometric and visualization analysis of hydrogel research in spinal cord injury: comparative study of Chinese and English literature.
    Wenju Bai, Xiaoyuan Huang, Jian Liu, Kamiran Halike, Jinyong Li, Xv Zhang, Tengwu Chang, Jichao Wang.
       Background: Over the past decade, the fields of hydrogel and spinal cord injury (SCI) research have witnessed rapid development. To explore disparities between China and global trends in hydrogel research, this study systematically conducted qualitative and quantitative analyses of related publications, summarizing current research foci and future directions. This provides critical guidance for researchers to delve deeper into hydrogel applications.
    Methods: A total of 866 records in the hydrogel and SCI domains were collected from the Web of Science Core Collection (WoSCC) and China National Knowledge Infrastructure (CNKI) between 2014 and 2024. CiteSpace, VOSviewer, SCImago, and the R package "bibliometrix" were utilized to analyze regional distributions, institutional collaborations, journal impacts, author productivity, and keyword trends.
    Results: Annual publications in hydrogel and SCI research exhibited consistent growth. China (n = 382) and the United States (n = 158) collectively contributed 76.2% of global academic output, reflecting disproportionate productivity. Zhejiang University and Jinan University demonstrated significant contributions across international and Chinese academic platforms. XIAO Jian distinguished himself through exceptional metrics (h-index, total citations), establishing his prominence as a high-impact scholar. BIOMATERIALS emerged as the most prolific and influential journal based on total link strength. Keyword and co-citation analyses revealed heightened emphasis on 3D bioprinting and electroactive bio-scaffolds in both WoSCC and CNKI databases. Systemic research disparities reveals that CNKI prioritize hydrogel technologies with a distinctive focus on indigenous specializations (e.g., Chuanxiongzine and stem cell transplantation), while WoSCC demonstrates notable advantages in establishing therapeutic loops encompassing drug delivery systems, functional recovery evaluation, and neuroimmune modulation strategies.
    Conclusion: By integrating WoSCC and CNKI data, this study comprehensively elucidates geographical disparities in research priorities between China and the global scientific community regarding hydrogel-mediated SCI repair, thereby proposing an evidence-based framework for international collaborative innovation. These insights offer valuable references to guide future hydrogel research.
    Keywords:  CiteSpace; bibliometric; comparative study; cord injury; hydrogel; visual analysis
    DOI:  https://doi.org/10.3389/fnins.2025.1636904
  40. J Immunol Res. 2025 ;2025 9813495
    Erratum to "Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis".
      [This corrects the article DOI: 10.1155/jimr/3393342.].
    DOI:  https://doi.org/10.1155/jimr/9813495
  41. Front Med (Lausanne). 2025 ;12 1516450
    Bibliometric analysis and visualization mapping of herpes zoster vaccine publications from 1999 to 2024.
    Wenli Gao, Dongyang Gao, Lin Li, Juan Li, Xinyi Yao, Junling Zhang.
       Background: Herpes Zoster (HZ) is a viral skin disease caused by reactivation of latent Varicella Zoster Virus (VZV) in human ganglia, presenting with unilateral neuropathic pain and vesicular rash. HZ imposes significant burden on patients and healthcare systems, often complicated by postherpetic neuralgia (PHN). The live attenuated zoster vaccine (ZVL, Zostavax) reduces HZ risk by 51% and PHN by 65% in adults ≥60 years. The recombinant zoster vaccine (RZV, Shingrix) shows approximately 90% efficacy in adults ≥50 years. Despite withdrawal of Zostavax from the U.S. market, RZV uptake remains suboptimal due to vaccine hesitancy and provider knowledge gaps. This study aims to analyze global research trends on HZ vaccines using bibliometric methods.
    Methods: Publications on "herpes zoster" and "zoster vaccine" were retrieved from the Web of Science Core Collection (WoSCC) database (1999-2024). Bibliometric and visualization tools including CiteSpace, VOSviewer, and R-bibliometrix were applied to analyze contributions by countries, institutions, journals, authors, references, and keywords.
    Results: A total of 719 articles from 261 journals across 56 countries were included. The United States led publications, with GlaxoSmithKline (GSK) as the most prolific institution. Vaccine was the most prolific journal; Levin et al. was the most productive author. The most cited article, "Efficacy of the Herpes Zoster Subunit Vaccine in Adults Aged 70 Years or Older," by Cunningham AL, appeared in the New England Journal of Medicine. Frequently used keywords included "herpes zoster," "vaccination," "postherpetic neuralgia," "efficacy," "subunit vaccine," and "safety".
    Conclusion: This bibliometric study comprehensively summarizes HZ vaccine research over 25 years, offering insights to guide future research and clinical practice.
    Keywords:  CiteSpace; Shingrix; VOSviewer; Zostavax; herpes zoster
    DOI:  https://doi.org/10.3389/fmed.2025.1516450
  42. Infect Med (Beijing). 2025 Sep;4(3): 100194
    The growing interests in Epstein-Barr virus: A bibliometric analysis of research trends, collaborations, and emerging hotspots.
    Lu Li, Jialin Wu, Jianghui Cai, Muhammad Arif Asghar, Rui Xiao, Jingwei Wu, Qinjian Zhao, Xiao Zhang.
       Background: Epstein-Barr Virus (EBV) is a widespread human γ-herpesvirus linked to cancers and autoimmune diseases, but limited comprehensive bibliometric analysis appear to have been conducted in this field.
    Methods: Using Web of Science data, 16,318 EBV-related documents (2014-2023) were analyzed via VOSviewer, Bibliometrix, and Citespace following the Strengthening the Reporting of Observational Studies in Epidemiology reporting guideline.
    Results: This cross-sectional bibliometric analysis of 16,318 EBV-related documents (2014-2023) revealed a consistent upward trend in annual publications, reflecting growing global interest in EBV research. Collaborative networks demonstrated strong international partnerships, particularly between the United States and China. Keywords co-occurrence and burst analysis highlighted enduring focus on EBV pathogenesis, immune evasion mechanisms, and EBV-associated diseases like nasopharyngeal carcinoma, Hodgkin lymphoma, and multiple sclerosis. On the basis of this comprehensive bibliometric analysis, it showed that the emerging hotspots included immunotherapy, biomarkers, viral reactivation, and vaccine development, with clinical trials evaluating immune-checkpoint inhibitors of toripalimab, mRNA-based therapeutic vaccines targeting LMP2 and EBNA1, and prophylactic strategies such as glycoproteins-based ferritin nanoparticles or mRNA vaccines, indicating a shift toward precision interventions.
    Conclusions: EBV research has grown exponentially, driven by insights into structural-function relationships and immune evasion. Advances enable targeted prophylactic/therapeutic strategies. The analysis highlights needs to decode virus-host interactions, optimize vaccines, and translate findings clinically, aiming to raise disease awareness, guide immunotherapies, and reduce global health burdens.
    Keywords:  Bibliometrics analysis; Epstein–Barr virus; Immunotherapy; Pathogenesis; Vaccine development
    DOI:  https://doi.org/10.1016/j.imj.2025.100194
  43. Regen Ther. 2025 Dec;30 341-350
    Global research dynamics in the induced pluripotent stem cell and diabetes: A bibliometric analysis of the past twenty years.
    Jiatong Wang, Sirui Huang, Kaiyuan Li, Jing Li, Xin Huang.
       Objectives: Induced pluripotent stem cells (iPSCs) have the potential to differentiate into insulin-producing β cells, offering a promising avenue for the treatment and research of diabetes. However, a comprehensive quantitative analysis of their specific impact in the field of diabetes has yet to be conducted. This study aims to analyze the current status and research hotspots of induced pluripotent stem cells in the field of diabetes over the past two decades, providing a reference for future research directions.
    Methods: This study performed a bibliometric analysis of recent literature on induced pluripotent stem cells in the field of diabetes, with data sourced from the Web of Science database. Using R software and VOSviewer, keyword clustering and research themes were analyzed to uncover trends and frontiers in this field.
    Results: The research included a total of 610 studies on induced pluripotent stem cells in the field of diabetes. In recent years, research in this field has shown a global upward trend, with the number of publications experiencing exponential growth from 2008 to 2021. However, the period from 2022 to 2025 is expected to be a plateau phase with fluctuations, gradually slowing down. The United States is the leading country in terms of publications, followed by China, Japan, the United Kingdom, and Italy. The United States not only leads in the number of publications but also has a broader network of international collaborators. Stem Cell Research and Diabetes are the most frequently published and cited journals. Currently, the application of iPSCs in studying the pathological mechanisms of diabetes and disease modeling has become a research hotspot. iPSCs provide an important in vitro platform for understanding the pathogenesis of diabetes and can also be used for drug screening, gene expression profiling, and studying the degeneration process of β-cells. Additionally, the use of iPSCs in the generation and regeneration of pancreatic β-cells, as a frontier of regenerative medicine and stem cell therapy, demonstrates the potential to restore normal islet function in diabetic patients. Furthermore, integrating immune evasion mechanisms and gene therapy, particularly by enhancing islet cell survival and function through immune regulation and genetic modification, is emerging as a new direction for diabetes treatment.
    Conclusion: The differentiation of induced pluripotent stem cells into β cells may offer a pathway to curing diabetes. This article systematically analyzes the current status and research hotspots of induced pluripotent stem cells in the diabetes field, providing valuable references for future clinical practice and research.
    Keywords:  Diabetes; Disease modeling; Gene therapy; iPSC
    DOI:  https://doi.org/10.1016/j.reth.2025.06.015
  44. Biomimetics (Basel). 2025 Jul 19. pii: 477. [Epub ahead of print]10(7):
    Global Research Trends in Biomimetic Lattice Structures for Energy Absorption and Deformation: A Bibliometric Analysis (2020-2025).
    Sunny Narayan, Brahim Menacer, Muhammad Usman Kaisan, Joseph Samuel, Moaz Al-Lehaibi, Faisal O Mahroogi, Víctor Tuninetti.
      Biomimetic lattice structures, inspired by natural architectures such as bone, coral, mollusk shells, and Euplectella aspergillum, have gained increasing attention for their exceptional strength-to-weight ratios, energy absorption, and deformation control. These properties make them ideal for advanced engineering applications in aerospace, biomedical devices, and structural impact protection. This study presents a comprehensive bibliometric analysis of global research on biomimetic lattice structures published between 2020 and 2025, aiming to identify thematic trends, collaboration patterns, and underexplored areas. A curated dataset of 3685 publications was extracted from databases like PubMed, Dimensions, Scopus, IEEE, Google Scholar, and Science Direct and merged together. After the removal of duplication and cleaning, about 2226 full research articles selected for the bibliometric analysis excluding review works, conference papers, book chapters, and notes using Cite space, VOS viewer version 1.6.20, and Bibliometrix R packages (4.5. 64-bit) for mapping co-authorship networks, institutional affiliations, keyword co-occurrence, and citation relationships. A significant increase in the number of publications was found over the past year, reflecting growing interest in this area. The results identify China as the most prolific contributor, with substantial institutional support and active collaboration networks, especially with European research groups. Key research focuses include additive manufacturing, finite element modeling, machine learning-based design optimization, and the performance evaluation of bioinspired geometries. Notably, the integration of artificial intelligence into structural modeling is accelerating a shift toward data-driven design frameworks. However, gaps remain in geometric modeling standardization, fatigue behavior analysis, and the real-world validation of lattice structures under complex loading conditions. This study provides a strategic overview of current research directions and offers guidance for future interdisciplinary exploration. The insights are intended to support researchers and practitioners in advancing next-generation biomimetic materials with superior mechanical performance and application-specific adaptability.
    Keywords:  biomimetic lattices; computational modeling; energy absorption; lattice mechanics; lattice structures; smart materials; structural optimization
    DOI:  https://doi.org/10.3390/biomimetics10070477
  45. Endocr Metab Immune Disord Drug Targets. 2025 Jul 22.
    NLRP3 Inflammasome: A New Perspective on Revealing Hotspots and Trends in Uric Acid Metabolism Disorders through Bibliometric Analysis.
    Yi Xu, Yu Wang, Chengjin Lu, Zeyu Liu, Zhijian Lin, Xiaomeng Zhang, Bing Zhang.
      Uric acid metabolism disorders have become major health concerns, primarily causing conditions such as hyperuricemia, uric acid nephropathy, and gout. Recent research has focused on these disorders' underlying pathological mechanisms and pharmacological treatments, emphasizing the role of the NLRP3 inflammasome. This study aims to analyze and summarize the current research status, hotspots, and trends in this field from a new perspective of the NLRP3 inflammasome, providing insights for future research and disease treatment. Based on the Web of Science Core Collection (WoSCC), this study systematically retrieved all publications related to the NLRP3 inflammasome and uric acid metabolism disorders published between 2009 and 2023. A comprehensive statistical analysis and visualization of the gathered data were conducted using VOSviewer, CiteSpace, R-bibliometrix, Microsoft Excel, Scimago Graphica, and Pajek. A total of 585 articles from 250 journals spanning 49 countries/regions worldwide were identified, demonstrating a consistent annual increase in publications. China contributed the largest number of publications, followed by the United States and South Korea. FRONTIERS IN IMMUNOLOGY emerged as the most prolific journal, while ANNALS OF THE RHEUMATIC DISEASES boasted the highest impact factor. The current research hotspots can be broadly categorized into three themes: the molecular mechanisms underlying NLRP3 inflammasome activation, the pathological mechanisms of NLRP3 inflammasome involvement in uric acid metabolism disorders, and the development of therapeutic compounds/ drugs targeting the NLRP3 inflammasome. Furthermore, the safety of drugs targeting NLRP3 inflammasome may emerge as a significant research trend in the future. Over the past 15 years, the crucial role of the NLRP3 inflammasome in uric acid metabolism disorders has attracted considerable attention. In the foreseeable future, the role of the NLRP3 inflammasome in uric acid metabolism disorders will continue to be a research focus. The development and safety of drugs targeting the NLRP3 inflammasome will remain a future research trend.
    Keywords:  NLRP3 inflammasome; frontiers.; gout; hotspots; hyperuricemia; uric acid metabolism disorders; uric acid nephropathy
    DOI:  https://doi.org/10.2174/0118715303376897250702230058
  46. Medicine (Baltimore). 2025 Jul 18. 104(29): e43381
    Nutrition in palliative care at the end of life: Bibliometric and network analysis until 2024.
    Carlos Álvaro Araújo, Rauany Fiuza Braga Pires de Melo, Geisa Sant Anna, Fábio Ferreira Amorim.
       INTRODUCTION: Food consumption is not only driven by a desire for nutrients and satiety but also a fundamental element of human interaction. This study aimed to comprehensively analyze bibliometric characteristics, collaboration networks, points of interest, and research trends, providing insights into the current landscape of publications on nutrition in palliative care at the end of life (PC-EOL).
    METHODS: The Web Wof Science Core Collection database was screened for studies addressing PC-EOL, published until December 2024. From the search results, we performed statistical descriptions of the year of publication, study type, authors, country, institution, keywords, scientific journal, citations, and disciplinary (Web of Science category). VOSviewer 1.6.19 (visualization of similarities), Microsoft Office Excel 16.78 for Mac, BibExcel, and the Bibliometrix R package, along with the Biblioshiny tool, were used for data analysis.
    RESULTS: Three hundred fourteen articles from 48 countries were included. Annual publications increased from 4 in 1994 to a peak of 35 in 2022 but declined over the past 2 years, reaching 16 in 2024. Most articles were from the United States, but the United Kingdom had the highest influence on the network. Keywords were stratified into 9 clusters: "Comprehensive End of Life Care," "Ethics and Decision-Making in End-of-Life," "Eating Disorders and Assisted Dying," "Palliative and Long-Term Care," "Palliative and Long-Term Care," "Advanced Nutritional Support," "Critical Care," "Family and Pediatric Care," "Advanced Cancer Management," and "Gastrointestinal Obstruction." Trend topic analysis suggests an increase in terms related to patients' refusal of nutrition/artificial nutrition, ethics, family, bereavement, and eating disorders, shifting from prior main themes, such as withdrawal/withholding life-sustaining therapy in advanced cancer/dementia. Among the top 20 cited articles, although all addressed nutrition in PC-EOL, it was the core element in only 9.
    CONCLUSION: The number of articles published annually remains limited, with low levels of collaboration among countries and authors. Few studies have examined the symbolic and relational meanings of food in terminal illness from the perspectives of patients and their families, dimensions crucial to truly person-centered care. Future research should prioritize the lived experiences, cultural contexts, and ethical concerns of those directly affected.
    Keywords:  and nutrition; diet; food; nutrition therapy; palliative medicine; terminal care
    DOI:  https://doi.org/10.1097/MD.0000000000043381
  47. Curr Neuropharmacol. 2025 Jul 18.
    Research Hotspots and Frontiers of Ischemic Stroke and Traditional Chinese Medicine: A Knowledge Mapping and Text Mining Analysis.
    Jian Xie, Teng Li, Yuan Zhang.
       BACKGROUND AND OBJECTIVE: Ischemic stroke is a complex neurological disease with poor prognosis, resulting in significant economic burdens for patients, their families, and society at large. Traditional Chinese Medicine (TCM) offers unique advantages and has been utilized for thousands of years in the prevention and treatment of ischemic stroke. However, there is currently a lack of bibliometric analysis and knowledge mapping regarding TCM treatments for this condition. To identify the key areas and future directions of TCM treatment for Ischemic Stroke.
    METHODS: We extracted articles on TCM treatments for ischemic stroke from the Web of Science Core Collection (WoSCC) database, spanning from January 1, 1990, to March 20, 2025, and conducted a bibliometric analysis. Data processing was performed using CiteSpace, VOSviewer, and Origin2024b.
    RESULTS: We collected 506 published papers, with China accounting for the majority of these publications (97.0 %, 418 articles). The Journal of Ethnopharmacology and Frontiers in Pharmacology were the two most frequently published journals. The leading institutions contributing to this research included the Chinese Academy of Medical Sciences, Beijing University of Chinese Medicine, and Peking Union Medical College (now known as Capital Medical University). The primary research hotspots in TCM treatment for ischemic stroke focused on protective effects, brain injury, and neural regeneration. Notably, network pharmacology, molecular docking, and metabolomics were identified as the commonly used research methods. Among them, network pharmacology was the most frequently used research method. Additionally, we summarized the TCM remedies that have been extensively researched and cited in the context of ischemic stroke, including catalpol, angong niuhuang wan, buyang huanwu decoction, jeo-dang-tang, yiqifumai powder injection, and gualou guizhi decoction.
    CONCLUSION: The work highlights the key topics and recent research frontiers, providing valuable resources for scholars interested in the role of TCM in treating ischemic stroke.
    Keywords:  Bibliometrics; Ischemic stroke; Network pharmacology.; Neural regeneration; TCM
    DOI:  https://doi.org/10.2174/011570159X378811250702095624
  48. Front Nutr. 2025 ;12 1575922
    Predicting the unseen: nutritional interventions as a key to combat frailty.
    Luya Shi, Xijiang Tian, Yih Bongsook, Jiameng Chen.
       Background: Frailty and malnutrition have emerged as critical public health issues amidst global population aging. Malnutrition not only significantly contributes to frailty but also intensifies its clinical symptoms, severely affecting the quality of life and health outcomes in older adults. Research in this field has accelerated in recent years; however, a comprehensive analysis of key research trends and hotspots remains absent. This study employs bibliometric methods to systematically analyze core themes and emerging research directions related to nutritional status and frailty in older adults, identifying potential research frontiers and guiding future development.
    Methods: A comprehensive search was conducted in the Web of Science Core Collection (WoSCC) database on November 6, 2024, using keywords relevant to frailty and nutrition status in older adults. Bibliometric analyses and knowledge mapping were performed using CiteSpace, VOSviewer, and R software.
    Results: Between 2005 and 2024, 2,357 publications on frailty and nutrition status in older adults were produced by 13,080 researchers from 3,987 institutions across 88 countries. The volume of publications has shown a consistent upward trajectory over the past two decades (R2 = 0.84), with projections indicating a continued increase, peaking at 315 publications by 2033. This sustained growth underscores the field's significance and ongoing research interest. Early research has centered on the "home-living elderly" demographic, while current investigations have shifted focus from molecular biology, genetics, and health nursing to more clinical and medical domains. Key areas of emphasis now include nutrition and dietetics, geriatrics, oncology, and pharmacology. Emerging research hotspots involve the early identification and management of malnutrition to reduce frailty-related health risks and improve health outcomes and quality of life for older adults. Notable trends include the keywords "prediction," "nutritional assessment MNA," "intervention," and "infection."
    Conclusion: This bibliometric analysis offers a comprehensive examination of the research evolution, hotspots, and emerging frontiers in frailty and nutrition status among older adults over the past two decades. The findings provide an objective overview of the academic landscape, offering valuable insights for future research, resource allocation, and policymaking.
    Keywords:  Bibliometrix; Citespace; VOSviewer; bibliometric analysis; elderly; frailty; nutrition status
    DOI:  https://doi.org/10.3389/fnut.2025.1575922
  49. Front Psychol. 2025 ;16 1521771
    Emotional climate: a bibliometric analysis of the psychological consequences of climate change.
    Yadgar Momenpour, Shahla Choobchian.
      Research on climate change and its impact on individuals' emotions are receiving increasing attention. Therefore, it is crucial to evaluate the current state of this research and predict future trends to offer greater clarity for researchers and decision-makers. This study aims to analyze the co-authorship network, bibliographic coupling, and co-word analysis of scientific documents produced by researchers in the Scopus database from 2010 to 2024. This period is characterized by the emergence and conceptual consolidation of emotional responses to climate change in academic research, focusing on the psychological consequences of climate change. A total of 1,333 documents were chosen for analysis after completing the identification and screening processes. This research is applied and descriptive in terms of its scient metric approach and is conducted using co-occurrence word analysis and network analysis techniques. The collected data were analyzed using Excel, and VOS viewer software was utilized to create visual maps. The co-occurrence analysis of high-frequency terms highlighted emerging topics and critical issues related to climate change. The findings emphasize the connection between clusters related to climate change and climate justice with the core cluster of humanity and human emotions, highlighting the emerging nature of this research domain. The thematic clusters identified further emphasize the significance and novelty of climate-related emotions and the organization of related research. This review can serve as a roadmap for future research, planning, and decision-making in the area of climate change and its associated impacts.
    Keywords:  Scopus; bibliographic coupling; climate emotions; climate psychology; co-word analysis; scientific mapping
    DOI:  https://doi.org/10.3389/fpsyg.2025.1521771
  50. Turk J Med Sci. 2025 ;55(3): 559-571
    Bibliometric analysis of colchicine in cardiovascular health: trends, key contributors, and global collaborations.
    Meltem Sertbaş, Özlem Özaydin, Habip Yilmaz, Abdullah Emre Güner, Özden Güdük, Nalan Okuroğlu, Ali Özdemir, Yaşar Sertbaş.
       Background/aim: The study aims to systematically analyze the body of literature concerning the effects of colchicine on the cardiovascular system, providing a comprehensive evaluation of the current knowledge and highlighting the clinical and scientific relevance of colchicine in this field.
    Materials and methods: Data were obtained from the Web of Science (WOS), Scopus, and PubMed databases on March 17, 2025. The search terms included "Colchicine" AND ("Cardiovascular Diseases" OR "Heart Diseases" OR "Coronary Artery Disease" OR "Myocarditis" OR "Pericarditis" OR "Atherosclerosis" OR "Heart Failure" OR "Myocardial Infarction" OR "Ischemic Heart Disease" OR "Acute Coronary Syndrome" OR "Cardiac Arrhythmias" OR "Thrombosis" OR "Stroke"). No restrictions were applied regarding publication date or language, ensuring the comprehensive retrieval of relevant data. Publications were categorized according to their document type and indexes. Additionally, a cooccurrence analysis of key words was conducted using VOSviewer 1.6.18.
    Results: A total of 425 publications on the effects of colchicine on the cardiovascular system were identified, published between 1976 and 2025. There has been a significant increase in research since 2015. Most publications were in the Cardiac Cardiovascular Systems category. "Colchicine" was the most frequently used key word, appearing 170 times. The USA ranked first in publication count, with 163 studies. The USA, Italy, Canada, and China played significant roles in global research collaboration.
    Conclusion: This bibliometric analysis demonstrates the increasing importance of colchicine as a therapeutic agent in the management of cardiovascular disease.
    Keywords:  Colchicine; bibliometric analysis; cardiovascular health
    DOI:  https://doi.org/10.55730/1300-0144.6003
  51. Front Immunol. 2025 ;16 1630817
    Corrigendum: Mapping knowledge structure and research of the biologic treatment of asthma: a bibliometric study.
    Jiamin Sun, Shiyao Bai, Jieyu Zhao, Danling Li, Xueqing Ma, Lin Ma, Xinming Su.
      [This corrects the article DOI: 10.3389/fimmu.2023.1034755.].
    Keywords:  asthma; bibliometric analysis; biologics; treatment; visualization analysis
    DOI:  https://doi.org/10.3389/fimmu.2025.1630817
  52. Medicine (Baltimore). 2025 Jul 18. 104(29): e42985
    Research on medical errors exhibits diverse associations with global indicators of science, development, and health across geographic regions: A scientometrics study.
    Mauro Ali Revolledo Caicedo, Andrés Fernando Montoya Obando, David A Hernández-Páez, Ornella Fiorillo-Moreno, Johana Galván-Barrios, Patricia Delgado, Ivan David Lozada-Martinez.
       BACKGROUND: Medical errors are a major public health concern, contributing to increased morbidity, mortality, and healthcare costs worldwide. Understanding the global research landscape on medical errors and its association with key health and development indicators can provide insights into gaps and opportunities for improving patient safety.
    METHODS: A scientometrics analysis was conducted using data from Scopus, PubMed, and other bibliographic databases. A mixed-methods approach was employed, integrating bibliometric indicators with global health and research metrics. Regression models and meta-analyses were applied to evaluate associations between research productivity and health indicators across 6 World Health Organization regions.
    RESULTS: A total of 2639 articles on medical errors were analyzed. The Americas produced the highest volume of research (48.01% of publications) with the highest citation impact (mean 46.5 citations per article). In contrast, Africa had the lowest research output (0.87%). Significant associations were observed between medical error research productivity and health indicators, including reductions in adolescent mortality (Coef. = -3676.56, P < .001) in the Western Pacific and under-5 mortality (Coef. = -0.18, P < .001) in the Americas. Each region showed a distinct pattern of associations with the global indicators. Research funding and health expenditure were positively associated with publication output and citation impact.
    CONCLUSION: Medical error research exhibits regional disparities and significant associations with global health indicators. Investment in medical errors research is associated with improved health outcomes in some regions, underscoring the need for equitable resource allocation and enhanced international collaboration to address gaps in patient safety research.
    Keywords:  bibliometrics; global health; health care quality indicators; medical errors; meta-research; science
    DOI:  https://doi.org/10.1097/MD.0000000000042985
  53. Future Oncol. 2025 Jul 21. 1-12
    Immunotherapy and combination treatments for triple-negative breast cancer: a Scopus bibliometric perspective.
    Ninie Nadia Zulkipli, Imilia Ismail, Wan Rohani Wan Taib, Sarina Sulong.
       BACKGROUND: Immunotherapy, a cornerstone treatment for triple-negative breast cancer (TNBC), has several limitations as a monotherapy. Global research is actively investigating effective combinatorial immunotherapy treatments for TNBC. Aim: This study aimed to elucidate an overview and research hot spots of immunotherapy and its combinatorial regimens in TNBC management for the past 5 years.
    MATERIALS & METHODS: Publications were retrieved from Scopus from 2019 to 2023 and analyzed using Harzing's Publish or Perish, Microsoft Excel, and VOSviewer.
    RESULTS: The study included a total of 1,818 publications, demonstrating increased publication trends over the years. The most productive continent, country, and journal were Asia (TP = 957), the United States (TP = 653), and Cancers (TP = 123), respectively. The United States and China exhibited the most dynamic inter-country collaboration, evidenced by the highest link strength (69). The United States emerged as the most influential country, recording the highest TLS (520). The analysis of co-occurrence author keywords revealed ICIs, PD-L1, and TME as research hot spots. The thorough integration of knowledge and research on these hot spots may offer an alternative in the management of TNBC.
    CONCLUSION: It is imperative to identify combinatorial immunotherapy treatments in order to have better cancer management.
    Keywords:  Combination treatments; Scopus; TNBC; VOSviewer; immunotherapy
    DOI:  https://doi.org/10.1080/14796694.2025.2531429
  54. Hum Vaccin Immunother. 2025 Dec;21(1): 2538330
    Bibliometric analysis of global research trends in pancreatic cancer immunotherapy.
    Tong Fu, Yuqing Chen, Hao Wang, Linlin He, Jian Zhang, Yongping Zhou, Xuchu Duan, Xu Zhang.
      Pancreatic cancer is a highly malignant tumor with poor prognosis and limited treatments. Immunotherapy shows promise in improving outcomes, but bibliometric analyses in this field are scarce. Our work reveals emerging trends, identifies research gaps, and highlights shifts in focus, offering valuable guidance for future research of immunotherapy and clinical practice. Pancreatic cancer immunotherapy bibliometric analyses were performed utilizing tools such as CiteSpace, VOSviewer, and RStudio, with a focus on the temporal and spatial distribution, prominent authors, research themes, keywords, and citation networks. The analysis reveals a significant increase in research activity on pancreatic cancer immunotherapy over the past decade, with hotspots including ICIs, CAR-T therapy, novel biomarkers, targeted therapies, the tumor microenvironment, and personalized treatment strategies. This study systematically reviews pancreatic cancer immunotherapy research progress from 1991 to 2024, highlighting key hotspots and trends. Future efforts should focus on ICIs, CAR-T therapy, and combination strategies, to enhance outcomes and extend patient survival.
    Keywords:  Pancreatic cancer; hotspots and trends; immunotherapy; therapy; treatment strategies
    DOI:  https://doi.org/10.1080/21645515.2025.2538330
  55. J Foot Ankle Res. 2025 Sep;18(3): e70062
    Bibliometric Analysis: Insights Into the Podiatric Medicine Landscape of Diabetic Sensory Peripheral Neuropathy and Genomics.
    Benjamin M Jones, Reuben J Pengelly, Alan M Borthwick, Catherine J Bowen.
       BACKGROUND AND AIMS: Research into diabetic foot complications is extensive; it remains challenging to identify critical literature. Evolving interprofessional boundaries, alongside advances in molecular medicine and pathophysiological understanding, necessitates mapping of the scientific literature (corpus). Impact of these advances on podiatric medicine remains unclear. This study explores topics, research performance, and evolution across the literature and disciplines to understand the corpus in its current state.
    METHOD: A retrospective-observational bibliometric analysis examined Web of Science publications using PRISMA search strategy (August 2023) to understand interconnectedness, direction, and intersectionality of subject disciplines, growth areas, and output. Curated phrases and disease focussed classification anchored investigation to diabetic peripheral neuropathy. Qualitative and quantitative approaches analysed publication meta-data (authors, citations, keywords) to map key concepts and scientific developments.
    RESULTS: Analysis of 589 records (1991-2023) revealed observational studies as the dominant design. Prominent concepts included risk, polyneuropathy, and prevalence, with authors favouring accessible terms (peripheral neuropathy) across specialisms. Leading research hubs were in England, Demark, USA, Qatar, Germany, and Italy. Diabetic Medicine and Diabetes Care remained the highest-cited journals, whilst the International Journal of Molecular Science, Cell Stem Cell, and Nature Reviews Neurology provided contemporary insights. Post-2016, methodological rigour and objectivity increased.
    DISCUSSION: Recurring topics included enhancing pre-clinical screening, addressing earlier diagnosis, pain management stratification with medicines optimisation, and reproducibility challenges. Case-controls increasingly replaced larger prospective, longitudinal study designs to improve diagnostic test accuracy and detection of diabetic neuropathy, particularly for neuropathic pain affecting small nerve fibres. Molecular approaches gained prominence signalling a shift from purely clinically derived approaches. The corpus responded to subjectivity and variable diagnostic criteria by prioritising objectivity. Emerging insights into channelopathies and mitochondrial dysfunction may augment current assessment/screening approaches to refine risk stratification and management strategies.
    Keywords:  bibliometric; diabetes; genomics; peripheral neuropathy; podiatry
    DOI:  https://doi.org/10.1002/jfa2.70062
  56. J Physician Assist Educ. 2025 Jul 24.
    Exploring Gender-Based Barriers in Physician Assistant Educator Authorship: Insights From a Physician Assistant Author Survey.
    Sara Lolar, Robert R Ehrman, Anne M Messman, Alexandria Garino.
       INTRODUCTION: Gender disparities in academic publishing hinder career advancement and limit diverse contributions in the physician assistant (PA) profession. Although many female PA educators publish successfully, the barriers they face remain underexplored. This study examined the challenges and facilitators of female authorship to inform strategies that promote equity in scholarly productivity.
    METHODS: First and last PA authors of Journal of Physician Assistant Education (JPAE) research articles (2014-2022) were identified. Identified authors were invited to participate in a survey, which was adapted, piloted among 8 faculty members, and distributed through Qualtrics. Descriptive statistics and inferential tests were applied.
    RESULTS: Among 177 unique PA authors, 69% identified as female. The response rate was 47%. Women had a median age of 49 years (IQR 44-60), compared with 55 years (IQR 41-64) for men. More men (40%) held full professor rank than women (20%). Women reported fewer first-author or last-author publications, lower levels of institutional support, and more frequent authorship conflicts (37% vs. 7.7%, P < .001), with 24% of women experiencing repeated disputes.
    DISCUSSION: Despite similar educational backgrounds, men held higher academic ranks and published more frequently. Women reported lower institutional support, which may contribute to disparities in research productivity. Authorship conflicts may further hinder female publication success and affect future collaborations. Addressing biases, improving collaboration, and ensuring equitable institutional support are essential for fostering gender equity in PA faculty advancement.
    DOI:  https://doi.org/10.1097/JPA.0000000000000694
  57. Neurosurgery. 2025 Jul 21.
    Letter: The Bibliometric Evolution of Neurosurgery Publications From 1977 to 2023.
    Zachary L Bernstein, Alexander J Schupper.
      
    DOI:  https://doi.org/10.1227/neu.0000000000003652
  58. Curr Top Med Chem. 2025 Jul 18.
    Advancements and Scientific Partnerships in the Application of Polysaccharides in Oral Formulations: A Bibliometric Analysis and Review.
    Jose Manuel Noguera Bazan, Layse Ribeiro de Sousa Carvalho, Lucas Dos Santos Silva, Arlindo Ribeiro da Silva Neto, Sergio Murilo da Silva Braga Martins, Luis Claudio Nascimento da Silva.
       INTRODUCTION/OBJECTIVE: The limitations of conventional drug delivery methods, such as systemic side effects and poor absorption, highlight the need for safer and more effective alternatives. Polysaccharides, due to their biocompatible, biodegradable, and mucoadhesive properties, have shown promise in formulations for the oral cavity, particularly in localized delivery systems and tissue regeneration. This study aims to conduct a bibliometric analysis to characterize the scientific output on the use of polysaccharides in the oral cavity, identifying trends, international collaborations, and research gaps.
    METHODS: A Web of Science search was conducted in January 2025 using keywords related to polysaccharides and mucosal adhesion. The analysis included original articles published in English between 2015 and 2024. Bibliometric data and study characteristics were extracted and analyzed, focusing on study types, formulation types, and international collaborations.
    RESULTS: The analysis included 66 articles with 1144 citations. In vitro studies were predominant, while clinical trials were lacking. Chitosan and alginate emerged as the most commonly used polysaccharides, with gels and hydrogels being the most prevalent formulations. International collaborations involved 28 countries, with China, Brazil, and Italy standing out in terms of scientific production.
    DISCUSSION: The results highlight important advancements in the use of polysaccharides for oral cavity formulations, particularly in gels and hydrogels. However, the predominance of in vitro studies and the lack of clinical trials suggest limitations for translating these findings into clinical practice. The strong performance of countries such as China, Brazil, Italy, Spain, and Norway underscores the relevance of international collaborations and the global potential of this topic.
    CONCLUSION: The increasing scientific output reflects the growing interest in the use of polysaccharides for oral health applications. Despite these advancements, critical gaps remain, such as the lack of clinical studies. Future research should prioritize translational studies, personalized therapies, and the sustainable development of biomaterials.
    Keywords:  Mucoadhesion; alginate; bibliometric.; chitosan; drug delivery; films; gellan gum; hydrogels; oral cavity; xanthan gum
    DOI:  https://doi.org/10.2174/0115680266371170250710010725
  59. J Clin Orthop Trauma. 2025 Oct;69 103121
    From residency to research excellence, mapping orthopaedic publication trends: A scoping review.
    Sari Wathiq Al Hajaj, Vishnu V Nair, Sanjeevi Bharadwaj, Preyeamvadha R, Hussein Shoukry, Sriram Harish Srinivasan.
       Background: Publications are critical for the future orthopaedic surgeon. The growing emphasis on academic output in orthopaedic residency programs has significantly impacted their career progression and fellowship opportunities. Mentorship, institutional support, and protected research time are crucial to enhancing publication rates among orthopaedic residents. This study aims to explore trends in publication among orthopaedic residents, examining the factors that influence their academic productivity and suggesting strategies to enhance output.
    Methods: A scoping review was conducted on the existing literature regarding publication trends among orthopaedic residents, factors influencing publication, and interventions to enhance research output. We searched the PubMed, Web of Science, Cochrane, and Google Scholar databases using keywords such as "orthopaedic resident," "academic productivity," "research output," and "publication trends." A total of 208 articles were reviewed, with a focus on 34 papers deemed relevant to our review.
    Results: Our review revealed a correlation between increased publications during residency and the successful completion of fellowships at high-ranking programs. Institutional support, mentorship, research infrastructure, and allocated research time have been identified as factors to enhance research output. Specifically, having a structured research curriculum and allocated research time have been demonstrated to improve the publication rate. Moreover, the utilisation of technology, including artificial intelligence and data analytics, has emerged as a mechanism to enhance research productivity among orthopaedic residents.
    Conclusion: We emphasised that publications are essential for the career development of orthopaedic residents. A robust research infrastructure, supportive mentorship programs, and the integration of research education into the residency curriculum are fundamental for achieving academic excellence. As orthopaedic residency programs evolve, addressing and prioritising research culture while leveraging technological innovations ensures the continued advancement of orthopaedic surgery.
    Keywords:  Academic productivity; Medical education; Orthopaedic residents; Publication trends; Research output
    DOI:  https://doi.org/10.1016/j.jcot.2025.103121
  60. Front Psychol. 2025 ;16 1563508
    The interplay between migration and self-identity: a structured review using TCCM and bibliometric analysis.
    Harshita Barua, Nidhi Maheshwari.
       Introduction: This study explores the intricate relationship between migration and self-identity, emphasizing how the migratory process extends beyond geographic movement to impact individuals' cultural, social, and psychological landscapes. As migrants adapt to new environments, shifts in language, traditions, and social norms may challenge their sense of belonging and self-concept, potentially resulting in identity conflicts and reduced confidence-particularly in workplace settings.
    Methods: A bibliometric review was conducted to systematically analyze the literature on migration and self-identity. Data were sourced from the Web of Science database. Analytical tools such as VOSviewer and Biblioshiny were employed to map co-citation patterns, thematic clusters, and emerging trends. Additionally, the Theory-Context-Characteristics-Methodology (TCCM) framework guided the synthesis of research gaps and future directions.
    Results: The analysis identified dominant research themes such as acculturation, identity negotiation, and sociocultural adaptation challenges. Most studies focus on Western host societies and adult migrant populations. However, there is a growing yet underexplored body of work on second-generation migrants and identity development in non-Western contexts.
    Discussion: Findings suggest a pressing need for more inclusive research across diverse cultural settings. Practically, organizations should recognize the impact of migration on self-identity and implement culturally sensitive policies to support migrant integration. Managerial implications include promoting inclusive workplace cultures through diversity training and mental health support programs.
    Keywords:  TCCM; acculturation; bibliometric review; co-citation; cultural adaptation; migration; self-identity; thematic mapping
    DOI:  https://doi.org/10.3389/fpsyg.2025.1563508
  61. Medicine (Baltimore). 2025 Jul 18. 104(29): e43310
    Exploring the emerging trends and hot topics of 5G technology application in wireless medicine: A bibliometric and visualization analysis.
    Yunfan He, Jun Xie, Zheyang Weng, Fangyu Yang, Yutao Wei, Jun Liang, Jianbo Lei.
       BACKGROUND: The online diagnosis and treatment model based on 5th generation mobile communication (5G) technology is one of the important ways to solve the imbalance between supply and demand of medical services.
    OBJECTIVE: We systematically summarized Chinese and English literature on the application of 5G technology in the field of wireless medical and conducted a literature feature analysis.
    METHODS: We used bibliometrics to quantitatively analyze the research trends and hot topics and comparatively analyzed the differences between research in China and other countries.
    RESULTS: This study analyzed 1344 articles and found that China provided the most funding (531 [75.32%]) and far outnumbered other countries in this field (1014 vs 330), but the quality of articles and effective collaboration between authors need to be improved. The hot topics in this field have gradually shifted from the construction of 5G internet hospitals during the COVID-19 to the construction of smart hospitals based on the Internet of Medical Things, and the research focus has gradually shifted from the data transmission layer such as wearable devices to the application layer of smart medical services.
    CONCLUSION: Researchers can further refine the specific application of 5G technology in the field of wireless medical from the 3 major areas of the smart hospital system.
    Keywords:  5G technology; hot topics; mobile health; smart hospital; telemedicine; wearable device
    DOI:  https://doi.org/10.1097/MD.0000000000043310
  62. JSES Rev Rep Tech. 2025 Aug;5(3): 430-434
    Academic metrics and publication history of presenters at the American Shoulder and Elbow Surgeons closed annual conferences from 2016 to 2022.
    Aaron M Atlas, Christina Montesano, Brandon Klein, John Grossi, Kyle Cullin, Randy M Cohn.
       Background: The American Shoulder and Elbow Surgeons (ASES) holds annual educational meetings to highlight new advances in the field of shoulder and elbow surgery. This study aims to assess the academic metrics of lecturers, ICL instructors, and moderators at ASES annual meetings.
    Methods: A review of selected presenters (lecturers, ICL instructors, and moderators) at ASES annual meetings from 2016 to 2022 was performed. Presentation topics were categorized into ten topic-specific content areas. Presenters' Hirsch index (H-index), number of topic-specific publications, and field-weighted citation impact (FWCI) were examined to assess academic metrics.
    Results: Overall, 348 presenters were evaluated. 76.6% of presentations were provided by physicians with at least 1 prior topic-specific publication. Lecturers and symposium moderators had the highest average proportion of presenters with previous topic-specific publications (81.5%), followed by ICL instructors (72.7%). The most commonly presented content topics included arthroplasty techniques (16.8%), followed by rotator cuff tears (15.9%) and surgical complications (12.4%). Infections-prophylaxis and treatment was the least presented topic (3.1%). Lecturers discussing infection held the highest average FWCI (2.55), while elbow injuries had the highest average H-index (59.6). ICL instructors discussing rotator cuffs had the highest average FWCI (4.7), while ICL instructors on biologics had the highest H-index (58.0). Symposium moderators on infection held the highest average FWCI (2.8), while those discussing nonclinical/orthopedic topics had the highest average H-index (55).
    Conclusion: A high percentage of ASES presenters had previous topic-specific publications as well as distinguishable H-indices and FWCI. Speakers at ASES annual meetings are academically accomplished within the field of shoulder and elbow surgery.
    Keywords:  ASES conference; Academic metrics; Conference Presenter Metrics; Education; Publication history; Shoulder and Elbow Surgery; Shoulder and elbow surgeons
    DOI:  https://doi.org/10.1016/j.xrrt.2025.01.013
  63. Perioper Med (Lond). 2025 Jul 22. 14(1): 76
    Global research trends of neuroinflammation in perioperative neurocognitive dysfunction: a bibliometric analysis.
    Shiqian Huang, Yuxi Zhou, Jie Liu, Shujun Sun, Tianhao Zhang, Lulin Ma, Shiya Liu, Daling Deng, Shaofang Shu, Yu Wang, Yin Yuan, Xiangdong Chen.
      Perioperative neurocognitive dysfunction (PND) is a significant complication in elderly surgical patients, characterized by cognitive decline and often linked to neuroinflammation. This study conducted a bibliometric analysis of 744 publications on PND-related neuroinflammation from 1999 to 2023, using the Web of Science Core Collection (WoSCC) database. Tools such as VOSviewer, CiteSpace, and Microsoft Excel were employed to analyze publication trends, geographical distribution, and key research areas. Results showed a steady increase in publications, with China leading in output and the USA exerting significant influence. Key research areas included aging, cardiac surgery, microglial activation, and therapeutic targets. Recent studies focused on the NLRP3 inflammasome and microglial activation as central mechanisms. The analysis also identified emerging trends, such as the investigation of biomarkers and the potential of dexmedetomidine and sevoflurane in modulating neuroinflammation. This study provides a comprehensive overview of the evolving research landscape, highlighting the need for interdisciplinary collaboration and the development of novel therapeutic strategies to address PND. Future research should focus on elucidating the complex interactions between neuroinflammation and cognitive decline and exploring personalized interventions to improve patient outcomes.
    Keywords:  Aging; Bibliometrics; Biomarkers; Cognitive dysfunction; Delirium; Microglia; Neuroinflammation; Neuropsychological tests; Postoperative cognitive complications; Surgery
    DOI:  https://doi.org/10.1186/s13741-025-00565-1
  64. Ann Surg Oncol. 2025 Jul 19.
    From Podium to PubMed: Successful Manuscript Publication of Oral Breast Surgery Abstract Presentations at National Meetings from 2017 to 2022.
    Margaret Summerside, Alexandra C Istl, Christine C Rogers, Adrienne N Cobb, Amanda L Kong, Puneet Singh, Chandler S Cortina.
       BACKGROUND: Less than half of scientific presentations result in manuscript publication. This study aims to assess manuscript publication rate for oral breast surgery abstracts at three national surgical conferences and examine factors associated with successful publication.
    METHODS: We performed a retrospective review of orally presented breast surgery abstracts from the American Society of Breast Surgeons (ASBrS), American College of Surgeons (ACS), and Society of Surgical Oncology (SSO) annual meetings from 2017 to 2022. Univariate and multivariate logistic and linear regression models were used to examine factors predictive of publication, journal impact factor, and time from presentation to publication.
    RESULTS: A total of 441 oral presentations met inclusion. Most presenting first authors were trainees (residents or fellows) (56.8%) or attendings/faculty (26.7%). Overall manuscript publication rate was 60.5% (n=267) and was 81.1% for ASBrS, 43.0% for ACS, and 63.4% for SSO. On unadjusted models, compared to medical students, trainees (OR 2.2, 95% CI 1.1-4.5) and attendings/faculty (OR 2.9, 95%CI 1.4-6.4) were more likely to publish (p<0.05). On multivariate analysis, abstracts presented at ACS (OR 0.2, 95%CI 0.11-0.36, p<0.001) and SSO (OR 0.4, 95%CI 0.25-0.79, p<0.001) had lower odds of publication than those presented at ASBrS. Median journal impact factor was 3.7 and median time to publication was 5 months (IQR 2-12.5).
    CONCLUSION: First author role and meeting type were predictive of manuscript publication for breast surgery presentations at national meetings on unadjusted and multivariate models, respectively. Findings may inform abstract submissions and underscores the need to support medical students to publish their work.
    Keywords:  Breast; Conference; Manuscript; Oncology; Presentation; Publication; Surgery
    DOI:  https://doi.org/10.1245/s10434-025-17852-2
  65. Zhongguo Zhong Yao Za Zhi. 2025 Jun;50(11): 3070-3078
    [Frontier technologies and development trends of network pharmacology: a patent bibliometric analysis].
    Li Tao, Zhi-Peng Ke, Tuan-Jie Wang, Zhen-Zhong Wang, Liang Cao, Wei Xiao.
      This study systematically analyzed the global research landscape, technological composition, and core patents in the field of networks target and network pharmacology, and proposes further suggestions based on the IncoPat patent citation database and VOSviewer bibliometric network visualization tool. Using patent literature metrics and scientific knowledge mapping method, technological innovation pathways, research hotspots, and future directions in this field were further revealed. In particular, this field is moving towards data-driven, intelligent, and systematic approaches. Patent analysis indicated that most patent applications in this domain focused on traditional Chinese medicine(TCM), which have provided key engineering technical approaches to explore and solve complex problems of TCM. By integrating big data and artificial intelligence technologies, network targets and network pharmacology have conferred high-precision screening and quality control of key components and targets in herbal formulations and prescriptions, accelerating the clinical translation and industrialization of TCM-based new drugs and health products with medicine-food homology. Therefore, it is essential to optimize the patent protection system and establish integrated technology platforms in this field for ensuring the competitiveness of technological achievements in research and clinical application. These efforts will advance the widespread application and high-quality development of TCM modernization, precision medicine, and innovative drug discovery.
    Keywords:  artificial intelligence; development trends; network pharmacology; network targets; patent analysis; traditional Chinese medicine formula
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20250410.701
  66. Urology. 2025 Jul 21. pii: S0090-4295(25)00693-4. [Epub ahead of print]
    GLOBAL COLLABORATION IN UROLOGICAL SURGERY RESEARCH BETWEEN HIGH- AND LOW-INCOME COUNTRIES: A BIBLIOMETRIC SCOPING REVIEW.
    Maxwell X Otiato, Kevin Muy, Kymora B Scotland.
       OBJECTIVE: To assess collaborations in global urological surgery research and trends in authorship representation for studies conducted in low- and middle-income countries (LMICs) METHODS: A systematic bibliometric scoping review was conducted using PRISMA guidelines to outline global collaboration patterns in urological surgery research. Literature searches in PubMed® and Scopus® included articles published from inception to January 1, 2024. Articles were included if they described urological surgery research involving a high-income country (HIC) conducted exclusively in LMICs. Articles were excluded if unrelated to urological surgery or if a collaboration between HICs and LMICs was not outlined. Data analysis was conducted from February to April 2024.
    RESULTS: A total of 1,777 peer-reviewed articles were identified and 108 studies met inclusion criteria. Most articles (89.8%) were published in 2009 or later. A significant majority of studies (81.5%) involved at least one author from the LMIC of focus and were considered collaborative. First and senior authors predominantly originated from HICs, particularly in studies based in low-income countries (88.2% and 94.1%). 52 articles (48.15%) were focused on educational initiatives, followed by training (23%) and humanitarian efforts (13%). Sub-Saharan Africa contributed the largest share of studies (19%), while Latin America and the Caribbean had the highest collaboration rates (20%). Endourology was the most frequently studied field across the research areas.
    CONCLUSION: This study highlights an upward trend in international urological surgery research with collaborative partnerships. These findings set a benchmark for promoting and sustaining equitable participation in global urological surgery research based in LMICs.
    DOI:  https://doi.org/10.1016/j.urology.2025.07.019
  67. Neurosurgery. 2025 Jul 21.
    In Reply: The Bibliometric Evolution of Neurosurgery Publications From 1977 to 2023.
    Michael M Covell, Christian A Bowers.
      
    DOI:  https://doi.org/10.1227/neu.0000000000003653
  68. J Cosmet Dermatol. 2025 Jul;24(7): e70363
    Applications of Traditional Herbal Ingredients in Skincare: Mapping the Research Landscape and Innovation Trajectories Over Four Decades.
    Kexin Deng, Yi Liu, Dian Li, Can Liu.
       OBJECTIVE: Along with economic and technological advancements, traditional herbal ingredients have garnered increasing attention in skincare due to their antioxidative properties, low toxicity, multitargeted effects, and broad cultural acceptance. However, there remains a lack of comprehensive knowledge frameworks and systematic research trend analyses in this field. This study examines the scientific landscape and innovation patterns of herbal skincare, aiming to establish a framework for integrating traditional wisdom with modern dermatological science.
    METHODS: A systematic literature search was conducted in the Web of Science Core Collection (SCI-E). CiteSpace, VOSviewer, and ArcGIS were employed to analyze leading contributors, research trends, and thematic evolutions.
    RESULTS: The analysis yielded 1593 papers authored by 753 researchers from 507 institutions across 102 countries. China emerged as the top contributor, while Industrial Crops and Products was the most highly cited journal, and Zengin, Gokhan, was the most prolific author. Geographical clustering and cultural convergence characterized the distribution of countries, institutions, and authors. Keyword clustering identified 20 research networks, with recent clusters including #6 "molecular docking," #7 "chromatography-mass spectrometry," and #15 "mixture design." Persistently trending keywords included "Mechanism," "Gut microbiota," "Network pharmacology," and "Association."
    CONCLUSION: Research on herbal skincare has evolved from raw plant usage to advanced refinement techniques, spanning animal, cellular, and molecular studies, including high-throughput screening approaches. Formulations have progressed from complex mixtures to single-compound extractions and bioactive monomers. A comprehensive research system has been established, yet standardization in dosage, application, and manufacturing remains crucial. Future studies should prioritize multicenter clinical trials and evidence-based validation. This study highlights the transition from empirical herbal applications to precision skincare, advocating for global collaboration between traditional medicine and modern regulatory science.
    Keywords:  healthy skin; herbs; plants; skin care
    DOI:  https://doi.org/10.1111/jocd.70363
  69. Int J Rheum Dis. 2025 Jul;28(7): e70359
    Bibliometric Analysis of Juvenile Idiopathic Arthritis From 2012 to 2023.
    Shuolan Jing, Shihao Li, Liqun Dong.
      
    DOI:  https://doi.org/10.1111/1756-185x.70359
  70. Acad Psychiatry. 2025 Jul 18.
    Who Leads Psychiatry? Demographics, Educations, and Scientific Contributions of US Academic Chairs.
    John L Havlik, Caitlin Radovan, Sayana Isaac, Syed Wahid.
       OBJECTIVES: This study aims to quantify the demographics, educational backgrounds, and scientific contributions of chairs of all university-based psychiatry departments in the USA.
    METHODS: Using the Fellowship and Residency Electronic Interactive Access Database, we identified chairs of all university-based psychiatry departments offering residencies (N = 120, female = 33.3%). We collected data on demographic, educational, and scientific variables through web search, departmental outreach, and secondary databases.
    RESULTS: The median age of psychiatry chairs was 60.5 (54-68) years, with a median age at appointment of 52 (47-59) years, a median of 34 (27-40) years after graduation from medical school. Forty (33.3%) chairs were female and 17 (14.2%) chairs were international medical graduates. 41.7% of chairs (n = 50) held additional higher education degrees. Chair education was highly concentrated among select institutions. Chairs exhibited strong academic productivity, with high median h-indices (median (interquartile range) 36 (11-59)), many publications (median (interquartile range) 102 (30.5-225.5)), and highly cited most-cited publications (median (interquartile range) 491 (130.5-1070.5)). Sixty-eight (56.7%) chairs had been or were currently the principal investigator of an R01 award, and 16 (13.3%) of the chairs were the current editor-in-chief of at least one peer-reviewed journal.
    CONCLUSIONS: This study provides a quantitative profile of university-based psychiatry department chairs, offering insights into the demographics, educational trajectories, and scientific contributions of the field's most influential leaders. These findings can both provide guidance for aspiring leaders in the field and encourage broader participation in leadership from those who are objectively qualified for these roles.
    Keywords:  Academic psychiatry; Leadership in psychiatry; Psychiatric education
    DOI:  https://doi.org/10.1007/s40596-025-02186-8
  71. J Environ Manage. 2025 Jul 21. pii: S0301-4797(25)02577-0. [Epub ahead of print]392 126601
    Trajectories and connections in socio-environmental disclosure research: A bibliometric mapping.
    Wesley Vieira da Silva, Hyandra Kalina Silva de Carvalho Gama, Maria Cádina Marques da Silva, Vinicius José Silva Oliveira, Luciano Luiz Dalazen, Victor Diogho Heuer de Carvalho.
      The objective of this research is to conduct a systematic review of scientific literature regarding socio-environmental disclosure. For this purpose, the Scopus and Web of Science journal databases were used to collect primary studies. Subsequently, the content of the abstracts was extracted using the content analysis technique. The analysis period of the corpus spans from 2009 to 2024, encompassing a total of 113 primary studies. The research protocol developed by Tranfield et al. (2003) was used, considering its stages: (i) review planning, (ii) review conduction, and (iii) report writing and dissemination of results. Additionally, the data from the final corpus were processed using the bibliometric software VOSviewer and Bibliometrix for comprehensive scientific mapping analysis. The analyzed results of the corpus indicate that the theme still has room for exploration in future studies. A co-citation analysis of the documents was also conducted, revealing three clusters of complementary strands: environmental disclosure practices, sustainability assurance, and organizational legitimacy. The corpus words were evaluated, revealing a measured association between construct performance (disclosure and corporate social responsibility - CSR) and other keywords. Among the pairs of words with statistically significant associations are "performance" and "organizations," as well as "legitimacy." These associations demonstrate a statistically significant relationship between the various measurement indicators related to Socio-environmental Disclosure. Finally, a list of future research proposals was provided so that those interested in the explored theme can further deepen their analysis of the knowledge on the subject in question.
    Keywords:  Scientific mapping; Socio-environmental disclosure; Sustainability
    DOI:  https://doi.org/10.1016/j.jenvman.2025.126601
  72. Neurol India. 2025 Jul 01. 73(4): 950
    Erratum: Bibliometrics and Visualization Analysis of Neuromuscular Junction Model.
      
    DOI:  https://doi.org/10.4103/neurol-india.neurol-india_8_25
  73. Ewha Med J. 2024 Apr;47(2): e16
    Current status and significance of research on sex differences in neuroscience: a narrative review and bibliometric analysis.
    Heajin Kim, Heisook Lee.
      This review aims to highlight the importance of research on structural, functional, molecular-biological, and disease-specific sex differences in the brain, and to examine current bibliometric indicators related to research on sex differences. The Web of Science Core Collection was searched for related articles from 2010 to 2023. Structural and functional brain differences according to sex, including variations in communication patterns between hemispheres, may play a role in mental disorders. Sex differences in neurotransmitters such as serotonin, dopamine, and γ-aminobutyric acid contribute to disparities in mental health, addiction, and neurodevelopmental conditions. Neurodevelopmental disorders such as autism spectrum disorder and schizophrenia exhibit sex-based differences in prevalence, symptoms, brain changes, and neurotransmitter disruptions under hormonal influence. There is a growing body of research on depression, adolescence, the hippocampus, the amygdala, and cognition, highlighting the importance of considering sex/gender factors. Recent studies on sex differences in brain diseases have identified variations in brain structure, function, and neurophysiological substances, as well as in hormones and genes between the sexes. The incidence of psychiatric disorders such as autism spectrum disorder, depression, anxiety, and Alzheimer's disease is increasingly being linked to sex differences, and the need for research into the mechanisms underlying these differences is gaining recognition. However, there remains a significant gap in sex-specific neuroscience research related to the diagnosis, treatment, prevention, and management of these conditions. Advancing inclusive research will require comprehensive training, a consensus on methodology, diverse perspectives through collaborative frameworks, governmental/institutional support, and dedicated funding to create suitable research environments and implementation strategies.
    Keywords:  Mental health; Neuroscience research, Bibliometric analysis; Psychiatry; Sex characteristics
    DOI:  https://doi.org/10.12771/emj.2024.e16
  74. Nature. 2025 Jul 22.
    How getting tenure changes researchers' publication habits - and citations.
    Max Kozlov.
      
    Keywords:  Careers; Research management
    DOI:  https://doi.org/10.1038/d41586-025-02320-4
  75. Proc Natl Acad Sci U S A. 2025 Jul 29. 122(30): e2500322122
    Tenure and research trajectories.
    Giorgio Tripodi, Xiang Zheng, Yifan Qian, Dakota Murray, Benjamin F Jones, Chaoqun Ni, Dashun Wang.
      Tenure is a cornerstone of the US academic system, yet its relationship to faculty research trajectories remains poorly understood. Conceptually, tenure systems may act as a selection mechanism, screening in high-output researchers; a dynamic incentive mechanism, encouraging high output prior to tenure but low output after tenure; and a creative search mechanism, encouraging tenured individuals to undertake high-risk work. Here, we integrate data from seven different sources to trace US tenure-line faculty and their research outputs at a remarkable scale and scope, covering over 12,000 researchers across 15 disciplines. Our analysis reveals that faculty publication rates typically increase sharply during the tenure track and peak just before obtaining tenure. Post-tenure trends, however, vary across disciplines: In lab-based fields, such as biology and chemistry, research output typically remains high post-tenure, whereas in non-lab-based fields, such as mathematics and sociology, research output typically declines substantially post-tenure. Turning to creative search, faculty increasingly produce novel, high-risk research after securing tenure. However, this shift toward novelty and risk-taking comes with a decline in impact, with post-tenure research yielding fewer highly cited papers. Comparing outcomes across common career ages but different tenure years or comparing research trajectories in tenure-based and non-tenure-based research settings underscores that breaks in the research trajectories are sharply tied to the individual's tenure year. Overall, these findings provide an empirical basis for understanding the tenure system, individual research trajectories, and the shape of scientific output.
    Keywords:  career trajectory; computational social science; innovation; science of science; tenure
    DOI:  https://doi.org/10.1073/pnas.2500322122
  76. Res Integr Peer Rev. 2025 Jul 23. 10(1): 13
    Systematic review and meta-analysis of quotation inaccuracy in medicine.
    Christopher Baethge, Hannah Jergas.
       BACKGROUND: Quotations are crucial to science but have been shown to be often inaccurate. Quotation errors, that is, a reference not supporting the authors' claim, may still be a significant issue in scientific medical writing. This study aimed to examine the quotation error rate and trends over time in the medical literature.
    METHODS: A systematic search of PubMed, Web of Science, and reference lists for quotation error studies in medicine and without date or language restrictions identified 46 studies analyzing 32,000 quotations/references. Literature search, data extraction, and risk of bias assessments were performed independently by two raters. Random-effects meta-analyses and meta-regression were used to analyze error rates and trends (protocol pre-registered on OSF).
    RESULTS: 16.9% (95% CI: 14.1%-20.0%) of quotations were incorrect, with approximately half classified as major errors (8.0% [95% CI: 6.4%-10.0%]). Heterogeneity was high, and Egger's test for small study effects remained negative throughout. Meta-regression showed no significant improvement in quotation accuracy over recent years (slope: -0.002 [95% CI: -0.03 to 0.02], p = 0.85). Neither risk of bias, nor the number of references were statistically significantly associated with total error rate, but journal impact factor was: Spearman's ρ = -0.253 (p = 0.043, binomial test, N = 25).
    CONCLUSIONS: Quotation errors remain a problem in the medical literature, with no improvement over time. Addressing this issue requires concerted efforts to improve scholarly practices and editorial processes.
    Keywords:  Citation errors; Medical publishing; Quotation errors; Quotation inaccuracy; Secondary quotations
    DOI:  https://doi.org/10.1186/s41073-025-00173-z
  77. Cureus. 2025 Jun;17(6): e86509
    Influence of Social Media on the Dissemination and Uptake of Cardiology Research.
    Moeed Ali Karim.
      The digital revolution has transformed the landscape of scientific communication, offering new tools for the dissemination and uptake of research. In cardiology, a field defined by rapid innovation and large-scale data generation, social media platforms have emerged as powerful adjuncts to traditional publishing methods. Platforms such as X (formerly Twitter), YouTube, and LinkedIn are increasingly used by journals, academic institutions, and individual clinicians to share research, engage in discourse, and promote knowledge translation. This literature review explores the existing body of research on social media's role in the dissemination and uptake of cardiology research. It discusses the influence of altmetrics, the impact on citation patterns, the integration into conference proceedings and continuing medical education, and highlights ethical considerations, including misinformation and professionalism. The review concludes with future directions for research and policy in this emerging field.
    Keywords:  cardiology; research; social media; twitter; youtube
    DOI:  https://doi.org/10.7759/cureus.86509
  78. Front Microbiol. 2025 ;16 1618046
    Nanomedicine in fungal keratitis: current applications and future prospects.
    Yuyang Xiao, Yifei Yang, Binyu Sun, Meng Yang, Jiamiao Lang, Mintao Dong, Zengsihan Chen, Shanshan Chen, Shengfeng Wang.
      Fungal keratitis (FK) poses a significant public health challenge, causing substantial harm to human health and the socio-economic landscape. However, due to the special anatomical and physiological characteristics of the eye, the current therapeutic drugs for FK are not effective, which brings obstacles to the clinical treatment of FK. Nanomedicine is a new therapeutic method that has emerged in the field of FK therapy in recent years. On the one hand, nanomaterials can directly kill fungi by separating ions, and on the other hand, the drug delivery system (DDS) composed of nanomaterials can target and deliver traditional drugs to the affected area and play a bactericidal role, with a significantly higher effect than traditional therapy. This review begins with a bibliometric analysis of research progress in FK nanomedicine. Then we describe the mechanism and effect of various nanomedicine in the treatment of FK from the perspective of direct and indirect treatment, focusing on the attack of nanomedicine on biofilm and DDS composed of nanomaterials. Finally, this field is prospected in order to provide new insights and ideas for the development of FK nanomedicine.
    Keywords:  bibliometric analysis; drug delivery system; fungal keratitis; nanomedicine; treatment
    DOI:  https://doi.org/10.3389/fmicb.2025.1618046
  79. Niger Med J. 2025 Mar-Apr;66(2):66(2): 681-691
    Perception of nurse academicians on academic publications: A cross-sectional study.
    Latha T, Suresh Kumar Sharma, Vipin Patidar, Rakhi Gaur, Santanu Nath, Shiv Kumar Mudgal.
       Background: Academic publication is a cornerstone of advancing nursing science, as it provides evidence-based research that guides clinical practice and education. However, the pressure to publish for career advancement has led to concerns about behaviours such as the 'urge to publish' and 'panic publishing'. The perception behind these trends remains unclear. This study aimed to assess the perception of Indian nurse academicians on academic publications.
    Methodology: This cross-sectional study surveyed Indian nurse academicians from Institutes of National Importance (INIs) of India who were selected convenient sampling technique. Data was collected through an online self-structured questionnaire. The survey covered socio-demographic details and perceptions for publishing in academic publications. Data analysis was performed using SPSS Version 26.0, with descriptive and inferential statistics. A significance level (p < 0.05) was used for statistical associations.
    Results: Of the respondents, 66.8% were female, and 92.3% had published before [median 12 (IQR 7-38) articles], with 21.7% preferring PubMed-indexed journals. More than two-thirds of participants (64.7%) spent an excessive amount of time on the publication process. There were differences by gender as men were more prone to assess publication metrics (p<0.05), ignore other facets of life for publishing (p=0.005), and self-reported publication addiction-like behaviors (18% compared to 4% for women).
    Conclusion: Academic publishing is a crucial but stress-inducing aspect of nurse academicians' careers. These findings underscore the need for a balanced approach that values quality over quantity in academic publishing. Institutions should promote ethical research practices, provide support to manage publication pressures and foster a more sustainable academic environment.
    Keywords:  Academia; Nurse Academician; Perception; Publications
    DOI:  https://doi.org/10.71480/nmj.v66i2.806
  80. Science. 2025 Jul 24. 389(6758): 336
    'Wandering scholars' analysis reveals how location drives productivity.
    Katie Langin.
      Concentrating funding at high-powered universities can maximize output but may sacrifice broader benefits.
    DOI:  https://doi.org/10.1126/science.aea8405
  81. Int J Surg. 2025 Jul 23.
    Limitations and recommendations for bibliometric insights into breast cancer organoid chips: trends & emerging areas- a commentary.
    Weibo Sun, Haoran Wang, Chun Lou.
      
    DOI:  https://doi.org/10.1097/JS9.0000000000003098
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