bims-evares Biomed News
on Evaluation of research
Issue of 2025–05–04
sixty-nine papers selected by
Thomas Krichel, Open Library Society
  1. Gender bias in Argentine rheumatology research: a bibliometric analysis.
  2. A bibliometric analysis of sentinel lymph node biopsy in melanoma of the top 90 cited publications.
  3. Exploration of research hotspots and evolutionary trends in osteosarcoma pulmonary metastasis: A comprehensive bibliometric analysis spanning five decades.
  4. Bibliometric analysis of the links between embryo transfer and endometrial receptivity: Mapping knowledge landscapes and emerging trends (2005-2024).
  5. Rise of Asian research in orthopaedic and sports medicine: a bibliometric analysis from 1996 to 2022.
  6. Global Analysis and Latest Research Hot Spots of Lipoedema/Lipodystrophy Investigation and Management: A Bibliometric Analysis and Visualized Review.
  7. Current hotspot and study trend of transcatheter aortic valve replacement, a bibliometric analysis from 2009 to 2023.
  8. Worldwide research performance on telemedicine for newborns and neonatal intensive care units: A bibliometric and visualization study.
  9. Research Progress in Pediatric Lung Transplantation: A Bibliometric Analysis.
  10. A bibliometric study for global hotspots and trends in animal-assisted interventions (1983-2023).
  11. Germany in pharmacology publishing: 192 articles with 1367 citations in Naunyn-Schmiedeberg's Archives vs. 16,775 articles with 274,225 citations elsewhere.
  12. Global research trends and basis of venous/lymphatic malformations during 2003-2023: a bibliometric study over two decades.
  13. Microbiome Research in Greece: A Comprehensive Bibliometric Study.
  14. Research trends on neutrophil extracellular traps in ischemic stroke: a scientific metrology study.
  15. Astigmatism research and application of vector method of the last half century: a bibliometric and visualized analysis.
  16. A scientometric, visualization, and content analysis on surgical endodontics from inception to 2023.
  17. Bibliometric analysis of hypospadias from 1998-2023.
  18. Bibliometric analysis of research trends and prospective directions of Akkermansia muciniphila from 2010 to 2024.
  19. The Impact of Women-Led Academic Collaborations in Plastic Surgery.
  20. A Bibliometric Review of Publications on Innovative Behaviors of Nurse Managers.
  21. Structural and temporal dynamics analysis on immune response in low-dose radiation: History, research hotspots and emerging trends.
  22. Global research trends in aquatic exercise therapy for musculoskeletal disorders: a bibliometric analysis.
  23. Mapping the research landscape of microRNA and stroke: a bibliometric analysis of insights, hotspots, and future directions.
  24. Global Trends in Diabetic Foot Research (2004-2023): A Bibliometric Study Based on the Scopus Database.
  25. Obesity and psychology: a bibliometric analysis of half a century.
  26. Research trends of the aetiology of systemic lupus erythematosus in the past 10 years: a bibliometric analysis (2014-2023).
  27. Comprehensive bibliometric analysis of transcranial magnetic stimulation-based depression treatment from 2003 to 2022: Research hotspots and trends.
  28. Trends and Future Projections in Ultrasonic Welding Research for Hybrid Materials.
  29. Visualizing global progress and challenges in esophagogastric variceal bleeding.
  30. Role of artificial intelligence in early identification and risk evaluation of non-communicable diseases: a bibliometric analysis of global research trends.
  31. Mapping the knowledge domains of literature on hepatocellular carcinoma and liver failure: a bibliometric approach.
  32. Research trajectory of the mechanism of preeclampsia: a scientometric perspective.
  33. Novel Tissue Engineering Scaffolds in the Treatment of Spinal Cord Injury-A Bibliometric Study.
  34. Global Research Trends, Hotspots, Impacts, and Emergence of Artificial Intelligence and Machine Learning in Health and Medicine: A 25-Year Bibliometric Analysis.
  35. Global trends in internet hospitals and electronic prescriptions: Insights for China.
  36. Gender Authorship Among Urology Artificial Intelligence Publications: A 10-Year Retrospective Analysis.
  37. A bibliometric analysis of rheumatology: knowledge structure and research trends of RNA-Binding proteins in rheumatic diseases.
  38. Research landscape and trends of internet addiction disorder: A comprehensive bibliometric analysis of publications in the past 20 years.
  39. Research hotspots and frontiers of neuromodulation technology in the last decade: a visualization analysis based on the Web of Science database.
  40. A Comprehensive Bibliometric Analysis of Orchitis Research from 1980 to 2023.
  41. A bibliometric mapping of advancements and trends in genome editing in pigs.
  42. A bibliometric and visual analysis of the impact of senescence on tumor immunotherapy.
  43. Bibliometric Analysis of Corporate Social Responsibility and Its Impact on Community Health.
  44. Mapping the landscape of mental health research through Google Trends: Bibliometric and thematic insights.
  45. Comparative bibliometric analysis of highly cited monkeypox research in general and specialized infectious disease journals: Dissecting trends, collaborations, and impact.
  46. A Bibliometric Analysis and Systematic Review of Research Advances in In Situ Gel Drug Delivery Systems from 2003 to 2023.
  47. Global Status, Recent Trends, and Knowledge Mapping of Olive Bioactivity Research Through Bibliometric Analysis (2000-2024).
  48. Visual analysis of research status and development trends in the field of postgraduate nursing education.
  49. Return of the Disruption Score: Fetal Surgery in the Spotlight (1975-2021).
  50. Mapping Research Trends on Intestinal Permeability in Irritable Bowel Syndrome with a Focus on Nutrition: A Bibliometric Analysis.
  51. Reputation shortcoming in academic publishing.
  52. A systematic review of hypervirulent Klebsiella pneumoniae research: bibliometric and topic modeling perspectives.
  53. Resident-led Research Initiative Drives Collaboration and Productivity: A Bibliometric Network-Based Analysis.
  54. Global research trends in perioperative care for diabetic patients: a bibliometric and visualized study.
  55. What Has Been Studied About Attitudes and Social Stigma Towards HIV/AIDS? A Global Bibliometric Study with Correlations on Global Health HIV-Related Indicators.
  56. Knowledge Mapping of International Microbiota Research: Analyzing Thirty-Year Citation Classics and Exploring Future Expectations.
  57. Persistent Gender Disparity in Authorship of Arthroscopic Surgery Research.
  58. Current Progress and Future Trends in Carbon Sources and Sinks in Farmland Ecosystems: A Bibliometric Analysis (2002-2023).
  59. Advances, Challenges, and Perspectives in Glomalin-Related Soil Protein Research.
  60. Publication trends for qualitative inquiry in American Psychological Association and Association for Psychological Science journals.
  61. Global trends in Marburg virus disease: Another potential threat to global health in the making?
  62. Defining Effect Size Standards in Temporomandibular Joint and Masticatory Muscle Research.
  63. Scientometric analysis of evolution in sex-specific MSC therapy for cardiovascular diseases.
  64. Global Research Hotspots and Progress on Acrylamide: Visualization Analysis.
  65. Academic Productivity at Orthopaedic Surgery Sports Medicine Fellowship Programs in the United States Has a Weak Positive Correlation With Nonresearch Lifetime Industry Earnings.
  66. H-index or Hype Index? Are High H-Index Surgeons the Real Influencers on Social Media?
  67. Academic Influence and Industry Funding in Acellular Dermal Matrix Research: A Co-authorship Network Analysis.
  68. Movement analysis congress from yesterday to today: Text mining analysis.
  69. "Go neurological physical therapy research, go"! Volume and methodological quality of neurological physical therapy: A 63-year PEDro database analyses.
  1. Rheumatol Int. 2025 Apr 26. 45(5): 126
    Gender bias in Argentine rheumatology research: a bibliometric analysis.
    Belén Navarro, Julieta Car, Gabriel Sequeira, Eduardo Mario Kerzberg.
      Despite growing female participation in the workforce, gender disparities persist across sectors. Little is known about how these manifest in academic rheumatology in Argentina. To analyze recently published rheumatology research by Argentine authors from a gender perspective. A bibliometric analysis was conducted on rheumatology publications from 2018 to 2022 in the Argentine Journal of Rheumatology (AJR) and PubMed-indexed journals that included at least one Argentine author. Argentine authors were classified by gender, and authorship roles (overall, first, and corresponding authors) were assessed, along with pharmaceutical industry conflicts of interest (COIs). Of 130 AJR articles (1183 Argentine authors), 61.8% were women. In 440 PubMed-indexed articles (1957 Argentine authors), 55.2% were women. Women were more frequently first authors in both AJR and PubMed (67.7% vs. 58.4%; p = 0.13), but less often corresponding authors in PubMed (44%) than in AJR (60%; p = 0.02). In AJR, female authors had a higher median number per article (3, Interquartile range or IQR 2-6) than male authors (2, IQR 1-4; p = 0.002). In PubMed, male authors showed slightly greater median participation (1, IQR 1-2 vs. 1, IQR 0-2; p = 0.02). In industry-sponsored studies, only 28.1% of authors were women. In COI-declaring publications, 71.0% listed only male disclosures; of 153 total reports, just 26.8% were by women. Although women are the majority in Argentine rheumatology research, they remain underrepresented in leadership roles and industry-funded studies. Continued monitoring of gender and COI data is needed.
    Keywords:  Authorship; Bibliometrics; Conflict of interest; Gender bias; Medical research; Rheumatology
    DOI:  https://doi.org/10.1007/s00296-025-05885-5
  2. Melanoma Manag. 2025 Dec;12(1): 2494979
    A bibliometric analysis of sentinel lymph node biopsy in melanoma of the top 90 cited publications.
    Zhen Yu Wong, Aisha Chaudry, Samuel Teklay, Zhen Ning Wong, Oluwatobi Adegboye, Pojsakorn Danpanichkul, Ryan Faderani, Muholan Kanapathy, Afshin Mosahebi.
       BACKGROUND: This bibliometric analysis aims to describe research trends and assess the methodological quality of the highest-impact SLNB research in melanoma.
    METHODS: We identified the 90 most cited publications on SLNB in melanoma using Web of Science, covering all available journal years (from 2005 to date). The Oxford Center for Evidence-Based Medicine (OCEBM) Levels of Evidence (LOE) were used to assess the methodological quality of each study.
    RESULTS: The 90 most cited publications on SLNB in melanoma collectively garnered 10,314 citations. Citation counts per publication ranged from 44 to 1,405 (mean 114.6 ± 185.2), with the highest-cited study authored by Professor Donald Morton et al. The majority of publications was classified as LOE 3 (n = 36). The United States of America (USA) led in publication output with 43 articles. Professors Merrick Ross (USA) and John Thompson (Australia) were the leading authors by publication count. The University of Sydney (Australia), University of Texas System, and Anderson Cancer Center (USA) were the top contributing institutions. Annals of Surgical Oncology published most articles.
    CONCLUSIONS: This bibliometric analysis provides a comprehensive overview and valuable reference for future researchers in the field of SLNB in melanoma.
    Keywords:  Sentinel lymph node biopsy; bibliometric analysis; citation analysis; cutaneous melanoma; melanoma
    DOI:  https://doi.org/10.1080/20450885.2025.2494979
  3. J Orthop. 2025 May;63 181-195
    Exploration of research hotspots and evolutionary trends in osteosarcoma pulmonary metastasis: A comprehensive bibliometric analysis spanning five decades.
    Chaojie Yu, Xiaohua Jiang, Shutian Wei, Chengxing Zhou, Chengyu Zhou, Yanshan Wei, Zhiping Su.
       Objective: Pulmonary metastasis frequently complicates osteosarcoma, making the investigation of its mechanisms and therapeutic strategies a focal point in both clinical medicine and biosciences. The explosive growth of the relevant literature has still not been systematically sorted out and summarized.
    Methods: Bibliometric methods were used in this study, Literature was retrieved from the Web of Science Core Collection, SCOPUS, and PubMed up until July 1, 2024. Bibliometric indicators were analyzed and research trends and hotspots in the field visualized using the Bibliometrix package, VOSviewer 1.6.19 and Citespace 6.3.R1 software.
    Results: A total of 1148 publications were reviewed, revealing that over the past five decades, the cumulative number of publications on pulmonary metastasis of osteosarcoma has gradually increased. China leads in the number of published papers, while the United States exhibits the most collaborative relationships with other countries. Italy is noted for the highest quality of research. Sun Yat-sen University is the most prolific institution, and the most productive author is Eugenie S. Kleinerman from the University of Texas MD Anderson Cancer Center. "Cancer" is the journal with the most publications, and Zhou Yan's 2020 paper received the highest local citations. Keywords such as "angiogenesis," "tumor microenvironment," and "surgery" appeared frequently, suggesting these topics are current research hotspots.
    Conclusion: "Immunotherapy", "survival", "chemotherapy", "prognosis", "biomarkers", "metastasectomy", "microRNA", "angiogenesis", "tumor microenvironment", and "surgery" define key research areas. Current hot topics include tumor-associated macrophages and the tumor microenvironment, which may hold the key to future therapeutic breakthroughs.
    DOI:  https://doi.org/10.1016/j.jor.2025.03.053
  4. Medicine (Baltimore). 2025 Apr 25. 104(17): e42014
    Bibliometric analysis of the links between embryo transfer and endometrial receptivity: Mapping knowledge landscapes and emerging trends (2005-2024).
    Chen Xu, Chuanhui Zhang, Shu Xu, Jingli Ma, Lingling Ran.
       BACKGROUND: Infertility is a significant global reproductive health challenge with varying prevalence across regions. While assisted reproductive technologies, especially in vitro fertilization, have created new possibilities for treating infertility, embryo transfer success remains limited by multiple factors, particularly endometrial receptivity. Understanding the relationship between embryo transfer and endometrial receptivity is crucial for advancing reproductive medicine and improving infertility treatment outcomes. To address the lack of bibliometric analysis in this field, we conducted a comprehensive bibliometric study of relevant academic literature.
    METHODS: We analyzed articles and reviews on endometrial receptivity and embryo transfer from the Web of Science Core Collection using CiteSpace, VOSviewer, and Bibliometrix package. The analysis focused on countries, institutions, journals, authors, keywords, and references.
    RESULTS: We identified 1478 documents published over 2 decades, showing an upward trend in annual publications. China led in publication volume, while the USA had the highest citation impact. The University of Valencia and Shanghai Jiao Tong University were the most productive institutions, with fertility and sterility being the leading journal. Simón, C emerged as the most influential author based on publication count and citations. Key research areas included comparing fresh versus frozen embryo transfer, addressing repeated implantation failure, and improving endometrial receptivity. The endometrial receptivity array for personalized embryo transfer represents an emerging research direction in reproductive medicine.
    CONCLUSION: This first comprehensive bibliometric analysis of embryo transfer and endometrial receptivity research provides valuable insights into knowledge development, research hotspots, and future directions in the field, serving as a crucial reference for scholars in reproductive medicine.
    Keywords:  Bibliometrics; Citespace; VOSviewer; bibliometrics; embryo transfer; endometrial receptivity
    DOI:  https://doi.org/10.1097/MD.0000000000042014
  5. Eur J Orthop Surg Traumatol. 2025 Apr 29. 35(1): 173
    Rise of Asian research in orthopaedic and sports medicine: a bibliometric analysis from 1996 to 2022.
    Sravya Teja Paleti, Srinivas B S Kambhampati, Abhishek Vaish, Raju Vaishya, Riccardo D'Ambrosi.
       OBJECTIVES: This study examines the growth and impact of orthopaedic and sports medicine (OSM) publications across 30 Asian countries from 1996 to 2022 using a bibliometric (scientometric) approach. Despite Asia's rising academic achievements, prior studies have not comprehensively mapped publication trends in this field across the region. This analysis aims to perform bibliometric analysis in OSM research in the Asian Countries.
    METHODS: Publication data were sourced from the SCImago Journal & Country Rank portal, derived from the SCOPUS database, covering the period from 1996 to 2022, with updates available until April 2023. The analysis focused on the top Asian countries and included key indicators such as H-index and total citations to assess research impact.
    RESULTS: The study identified a substantial rise in OSM publications from Asia, with total output increasing 14.27-fold-compared to a 5.54-fold increase globally. Between 1996 and 2022, 111,342 OSM publications originated from Asian countries, out of 666,847 globally. However, citation counts for Asian research declined from 26,263 in 1996 to 6020 in 2022, likely reflecting the time-lag effect in citation accumulation for recent publications. Possible contributing factors are discussed.
    CONCLUSION: This study highlights a remarkable surge in orthopaedic and sports medicine publications from Asia, surpassing global growth trends. While citation metrics appear lower in recent years-likely due to the recency of publications-the overall trend suggests a strong and growing research in Asia. China and Japan lead in output and impact, respectively, while India's rapid rise reflects increasing academic potential. However, enhancing research quality and visibility and reducing self-citation are essential to elevate global impact. Countries like Hong Kong, Singapore, and Sri Lanka demonstrate high citation efficiency. With optimal collaboration and strategic investment, Asian countries are well positioned to play a leading role in global orthopaedic research.
    Keywords:  Asia; Bibliometrics; Orthopaedics; Research; Sports medicine
    DOI:  https://doi.org/10.1007/s00590-025-04294-5
  6. Aesthetic Plast Surg. 2025 Apr 28.
    Global Analysis and Latest Research Hot Spots of Lipoedema/Lipodystrophy Investigation and Management: A Bibliometric Analysis and Visualized Review.
    Ammar Alsayegh, Ziyad Alsuwilem, Abdullah Alsalem, Abdullah Alanzan, Rasha Alashjaee, Maryam Almuslem, Obai Raffah, Rahaf Almutairi, Khalid Arab.
       BACKGROUND: Lipodystrophy presents clinical management challenges due to its varied expression and low incidence. Despite the clinical importance, there has been no systematic evaluation of the research output in terms of geographical distribution, institutional contributions, or emerging trends. This study aims to fill that gap by conducting a comprehensive bibliometric analysis of the global research landscape on lipodystrophy.
    METHODS: Utilizing the Web of Science core collection, studies from 2010 to 2024 were analyzed. Bibliometric indicators were processed using VOSviewer to identify trends through graphical co-occurrence mapping.
    RESULTS: A total of 826 studies from 57 countries were included. The USA led with 259 publications (30.51%). The most productive institutions were the National Institute of Diabetes and Digestive and Kidney Diseases with 43 publications (14.98%). Among 166 journals, the Journal of Clinical Endocrinology and Metabolism had the highest publications (43, 25.90%) and citations per publication (58). The most co-cited article was The Diagnosis and Management of Lipodystrophy Syndromes (2016), which was referenced 290 times.
    CONCLUSION: This analysis highlights research trends and collaborative networks, areas for future investigation, and identifies the gaps and emerging trends that will inform future research directions.
    NO LEVEL ASSIGNED: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  Bibliometric; Citation analysis; Collaboration network; Lipodystrophy; Lipoedema; Liposuction
    DOI:  https://doi.org/10.1007/s00266-025-04855-3
  7. Front Cardiovasc Med. 2025 ;12 1411561
    Current hotspot and study trend of transcatheter aortic valve replacement, a bibliometric analysis from 2009 to 2023.
    Ping Lai, Dekuan Zhang, Jin-Hua Xue, Shuquan Xu, Kejun Tian, Hong-Zhou Zhang, Bei Wang, Yi-Ming Zhong, Yong-Ling Liao.
       Introduction: Transcatheter aortic valve replacement (TAVR), alternatively termed transcatheter aortic valve implantation (TAVI), represents a seminal advancement in cardiovascular interventions by obviating the necessity for open-heart surgery traditionally associated with surgical aortic valve replacement (SAVR). This technique entails percutaneous delivery of a bioprosthetic valve. Despite the surfeit of literature on TAVR over the past fifteen years, a bibliometric analysis is conspicuously absent.
    Method: A query executed on the Web of Science Core Collection (WoSCC) on September 1, 2022, returned 8,359 articles and reviews pertinent to TAVR. Data interpretation leveraged Microsoft Excel, CiteSpace, and VOSviewer to illustrate trends and delineate focal points within the corpus of TAVR research.
    Result: The analysis incorporated 8,359 articles and reviews on TAVR from January 1, 2009, to August 1, 2023. Publication volume expanded from 35 in 2009 to a pinnacle in 2020, reflecting a near thirty folds increase, with citations escalating from 56 in 2009 to 27,354 in 2021. The United States prevailed in scholarly output (Np = 3,015), citation frequency (Nc = 70,991, excluding self-citations), and academic impact (H-index = 120). Columbia University was distinguished by the highest number of publications (Np = 380), citations (Nc = 41,051), and H-index (84). Within the author community, Rodes-Cabau J was preeminent, with 260 publications and an equivalent citation index and H-index. Keywords such as "balloon-expandable valve," "coronary access," "next-day discharge," "conducti on disturbances," and "coronary obstruction" have surfaced as the lexicon of burgeoning research themes.
    Conclusion: Investigation into TAVR has emerged as a major area of scholarly focus. The United States stands at the forefront of this research. Columbia University ranks as the preeminent institution in terms of publication output. Key research themes such as "balloon-expandable valve," "coronary access," and "coronary obstruction" are shaping up as current and prospective research hotspots, signaling potential areas for future study and innovation.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; research hotspot; transcatheter aortic valve replacement
    DOI:  https://doi.org/10.3389/fcvm.2025.1411561
  8. Digit Health. 2025 Jan-Dec;11:11 20552076251336283
    Worldwide research performance on telemedicine for newborns and neonatal intensive care units: A bibliometric and visualization study.
    Liyan Luo, Yaochen Lou, Chuyan Wu, Jiahui He, Feng Jiang.
       Background: Telemedicine uses videoconferencing technology to enable real-time audio and visual communication, linking on-site healthcare providers with specialists at remote locations. Over the past decade, telemedicine has grown significantly within the field of neonatology. This study seeks to deepen the understanding of telemedicine applications for newborns and neonatal intensive care units (NICUs) through a detailed bibliometric analysis.
    Methods: Publications on telemedicine in newborns and NICUs from January 1, 2004, to October 22, 2024, were retrieved from the Web of Science Core Collection. Using Microsoft Excel, CiteSpace, the R package "bibliometrix," and VOSviewer, we analyzed the data to examine the number of publications, contributing countries/regions, institutions, authors, journals, references, and keywords.
    Results: Since 2004, 1177 publications have been included, reflecting a rapid increase in research on telemedicine in newborns and NICUs over the past decade. These studies originated from 55 countries/regions and 139 institutions. The United States, the United Kingdom, and India were the primary contributors in terms of publication volume. Among the 405 authors analyzed, Jennifer L. Fang had the highest number of publications, while James P. Marcin received the most co-citations. BMC Pregnancy and Childbirth published the most articles, and Pediatrics had the highest citation count. The most frequently used keywords included "accuracy," "depression," "digital health," "mobile health," and "parents," highlighting key research areas. Emerging research frontiers such as "palliative care," "low-income populations," "artificial intelligence," and "parents with high-risk infants" indicate rapidly advancing topics in this field.
    Conclusions: This study is the first to perform a comprehensive bibliometric analysis of publications on telemedicine in newborns and NICUs. In the previous 20 years, global interest in teleneonatology research has significantly increased. Our bibliometric findings offer valuable insights for researchers, helping them understand essential information, recognize current research hotspots, identify potential collaborators, and explore future research frontiers in this field.
    Keywords:  NICUs; Telemedicine; bibliometric analysis; newborns; web of science
    DOI:  https://doi.org/10.1177/20552076251336283
  9. Thorac Cardiovasc Surg. 2025 Apr 30.
    Research Progress in Pediatric Lung Transplantation: A Bibliometric Analysis.
    Quan Yuan, Zixiong Shen, Zhiqin Li.
      Pediatric lung transplantation is considered to be an effective treatment for end-stage lung disease in children, and this study mainly conducts a bibliometric analysis in the field of pediatric lung transplantation.We used the web of science databases to perform a bibliometric analysis of the progress of research in the field of pediatric lung transplantation from 1996 to 2024. In addition, we used VOSviewer software and the "bibliometrix" package in R to visualize and analyze the authors, countries, journals, institutions, and keywords of the literature.We identified 359 literature studies related to pediatric lung transplantation, which were cited 6,387 times by 1,400 journals. The journal with the highest number of average citations was the "New England Journal of Medicine," while the journals with the highest number of publications were the "Journal of Heart and Lung Transplantation and Pediatric Transplantation." The United States was the country with the highest number of publications (64.3%), followed by the United Kingdom (11.1%) and Canada (8.08%).Research in the field of pediatric lung transplantation is currently on the rise, while research is still dominated by developed countries, with most developing countries in their infancy. Against the background of COVID-19 and global health challenges, the unique need for pediatric lung transplantation is becoming a trend.
    DOI:  https://doi.org/10.1055/a-2572-6428
  10. Front Psychiatry. 2025 ;16 1490122
    A bibliometric study for global hotspots and trends in animal-assisted interventions (1983-2023).
    Xiaowei Feng, Shanguang Zhao, Dong Zhang, Qing Yi, Yanlan Chen, Xinding Zhang.
       Background: As a therapeutic approach, Animal-Assisted Intervention (AAI) has gained increasing recognition for enhancing both psychological and physical health. However, bibliometric studies in this field remain scarce.
    Methods: This study aims to analyze AAI-related research from 1983 to 2023 using bibliometric methods. It examines sources of literature, core journals, highly cited documents, country and institutional distribution, prolific authors, and high-frequency keywords while tracking the evolution of research themes in AAI. A thematic search using the Boolean operator "OR" and AAI-related keywords in the Web of Science database yielded 405 articles, and data mining and visualization of these results were performed.
    Results: The findings reveal a substantial increase in the number of published articles and citations over the past decade, indicating a rising research interest in this field. The United States and Purdue University have played a leading role in this area. Currently, AAI research is shifting from basic studies to intervention strategies targeting specific populations and diseases. Future research trends may include enhanced international collaboration, standardization of research methods, and the development of more targeted interventions.
    Conclusion: These findings provide researchers, funding agencies, and policymakers with scientific insights and recommendations for future research directions in AAI.
    Keywords:  animal-assisted interventions; bibliometrics; nonpharmacological therapies; research trends; vulnerable groups
    DOI:  https://doi.org/10.3389/fpsyt.2025.1490122
  11. Naunyn Schmiedebergs Arch Pharmacol. 2025 May 01.
    Germany in pharmacology publishing: 192 articles with 1367 citations in Naunyn-Schmiedeberg's Archives vs. 16,775 articles with 274,225 citations elsewhere.
    Siddig Ibrahim Abdelwahab, Abdullah Farasani, Jobran M Moshi, Saeed Alshahrani, Waseem Hassan.
      Germany has played a central role in the development of Naunyn-Schmiedeberg's Archives of Pharmacology (NSAP), historically leading its publication output for nearly 150 years. However, recent bibliometric analysis of 25,935 articles revealed a dramatic decline in German contributions, with the country falling to fifth place between 2021 and 2025. To understand this shift, we conducted a comprehensive bibliometric study of 28,149 pharmacology- and toxicology-related publications from German institutions indexed in Scopus between 2019 and 2024. Our findings indicate a strong trend toward publishing in high-impact journals: 61% of the publications appeared in Q1 journals and 28% in Q2. Although NSAP ranked 28th in publication volume, the vast majority of German research-over 16,700 articles-was disseminated through other venues, many with significantly higher citation metrics. These shifts highlight the growing influence of bibliometric indicators on publication behavior. While such trends reflect global academic pressures, they also prompt a critical reflection on the value of legacy journals. We advocate for renewed institutional support and national awareness to maintain NSAP as a respected platform for pharmacological research, balancing impact metrics with scientific heritage.
    Keywords:  Germany; Journal metrics; Pharmacology research; Publications
    DOI:  https://doi.org/10.1007/s00210-025-04224-6
  12. Front Med (Lausanne). 2025 ;12 1555168
    Global research trends and basis of venous/lymphatic malformations during 2003-2023: a bibliometric study over two decades.
    Hongyuan Liu, Jun Zhu, Hui Chen, Xiaoxi Lin.
       Introduction: Venous/lymphatic malformations (VM/LM) represent a group of vascular anomalies that share similarities in diagnosis, classification, management, and pathogenesis. Despite growing research interest, no comprehensive bibliometric analysis has been conducted to map the knowledge landscape and evolution of VM/LM studies.
    Methods: We searched the Web of Science Core Collection database for VM/LM-related publications from January 2003 to December 2023. multiple analytical tools including VOSviewer, CiteSpace, and R package 'bibliometrix' were used to analyze publication trends, collaboration networks, and research hotspots.
    Results: 4,747 publications with 57,893 references were enrolled and analyzed. The number of publications is growing generally and erupted in 2019. The USA, China, and Japan are the top 3 countries in publication. The main study centers are scattered in the USA, Europe, China, and Japan. Fishman SJ published most. Vikkula M was cited most. Journal of Pediatric Surgery published and was cited most. The knowledge basis of VM/LM contains a wide range of concepts including classification/differential diagnosis, genetic causes, Sirolimus treatment, localized intravascular coagulopathy, and percutaneous treatment. The topic trend mainly changed after 2019 to genetic study and targeted therapy.
    Discussion: This is the first bibliometric analysis of VM/LM research demonstrating the field's rapid growth and shifting research hotspots. Four key future directions emerged: molecular-level diagnosis and classification, precision targeted therapy, advanced sclerotherapy techniques, and artificial intelligence applications. International collaboration between countries and centers needs to be strengthen. These findings provide an objective foundation for future VM/LM investigations.
    Keywords:  bibliometric; lymphatic malformation; vascular anomaly; vascular malformation; venous malformation
    DOI:  https://doi.org/10.3389/fmed.2025.1555168
  13. Microorganisms. 2025 Mar 24. pii: 725. [Epub ahead of print]13(4):
    Microbiome Research in Greece: A Comprehensive Bibliometric Study.
    Christos Stefanis, Christina Tsigalou, Ioanna Bezirtzoglou, Chrysoula Chrysa Voidarou, Elisavet Stavropoulou.
      Bibliometric analyses are increasingly used to evaluate scientific domains, revealing research trends, productivity, and impact. This study provides a bibliometric analysis of microbiome-related research conducted by Greek scientists. Data were retrieved from the Scopus database, using the keyword "microbiome" (English) for publications until December 2024. Bibliometric analysis was performed using VOSviewer and the bibliometrix package in R. Our findings indicate that research output has increased exponentially since 2018, with the National and Kapodistrian University of Athens and the Aristotle University of Thessaloniki leading microbiome research in Greece. Medicine, biochemistry, genetics, molecular biology, immunology, and microbiology are the predominant research fields. The keyword analysis highlights "microbiome", "microbiota", "probiotics", "prebiotics", "intestinal flora", and "16S rRNA" as central topics. Additionally, we acknowledge the role played by alternative microbial markers, including 18S rRNA/ITS sequencing, for fungal diversity studies. This bibliometric study demonstrates a dynamic and evolving research landscape in Greece and highlights the international relevance of Greek contributions to microbiome science.
    Keywords:  bibliometric; brain–gut axis; gut health; immune system; intestine flora; microbiome; microbiota; probiotics
    DOI:  https://doi.org/10.3390/microorganisms13040725
  14. Front Pharmacol. 2025 ;16 1537566
    Research trends on neutrophil extracellular traps in ischemic stroke: a scientific metrology study.
    Yaji Xu, Xingyu Gong, Yilin Wang, Xinyu Liu, Haomou Pu, Hongjie Jiang, Xiaoping Yu.
       Background: Ischemic stroke (IS) remains a leading global cause of mortality and chronic disability. Neutrophil extracellular traps (NETs), recently identified as neutrophil-derived structures that trap and neutralize pathogens, have increasingly drawn attention for their involvement in IS pathogenesis. Despite a surge in related research, no bibliometric analyses have yet examined the knowledge framework and trends within this emerging field. Here, we conducted a systematic bibliometric analysis to map the research landscape and identify current and potential hotspots regarding NETs in IS.
    Methods: Relevant literature published between 2014 and 2024 was systematically retrieved from the Web of Science Core Collection (WoSCC) database. Multiple analytical tools, including CiteSpace, VOSviewer, R package "bibliometrix," and Python scripts, were employed to explore publication trends, academic collaborations, prominent research themes, and emerging topics.
    Results: Ninety-two publications were eligible for bibliometric assessment, supplemented by an additional latent Dirichlet allocation (LDA)-based topic analysis of 4,504 documents. China (30 publications) and the United States (23 publications) emerged as leading countries in terms of research output, with global collaboration networks predominantly centering around the United States. Noteworthy contributions also arose from European institutions, particularly Katholieke Universiteit Leuven and Karolinska Institutet. The leading authors identified were Desilles, Jean-Philippe, Ho-Tin-Noé, Benoit, and Mazighi, Mikael. Journals such as Stroke, Annals of Neurology, and Nature Communications significantly influenced this domain. Three main research hotspots emerged: (1) "promoting effect of protein arginine deiminase 4 (PAD4) in NET formation," (2) "cell-free DNA as a biomarker for disease diagnosis," and (3) "influence of platelets and thrombosis on NETs-related diseases."
    Conclusion: Our study offers an extensive overview of existing literature and evolving research trajectories concerning NETs in IS, providing researchers with clear insights into current trends and future investigative directions. Nevertheless, our study has limitations-including dependence on a single database (WoSCC), restriction to English-language publications, and inherent constraints of the LDA methodology-that merit consideration in interpreting these findings.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; ischemic stroke; neutrophil extracellular traps; topic modelling
    DOI:  https://doi.org/10.3389/fphar.2025.1537566
  15. Front Med (Lausanne). 2025 ;12 1519487
    Astigmatism research and application of vector method of the last half century: a bibliometric and visualized analysis.
    Jiamei Zhang, Lulu Xu, Mengyuan Shan, Liyun Yuan, Yi Dong, Yan Wang.
       Background: As a common type of refractive error, astigmatism has always been one of the important factors affecting visual quality in clinical practice and it is quite an important public health burden. This study aims to evaluate astigmatism research and the clinical application of the vector method of the past half-century through a broad scientometric analysis, and to explore its reference value for guiding clinical treatment.
    Methods: The literature search was conducted on the Web of Science for astigmatic vector studies published from 1965 to August 2024. Retrieved publications were analyzed by the number of annual publications, prolific countries, and researchers, core publications and journals, and the number of citations through descriptive statistics. Collaboration networks and keyword analysis were visualized by VOSviewer and CiteSpace.
    Results: One thousand and fifty-nine publications were included for a visualized analysis. Vector methods help researchers to describe astigmatism specialized, and clinicians are mainly focused on the correction of astigmatism in both corneal and cataract surgery. Journal of Cataract and Refractive Surgery was the core journal for this field. The United States accounts for the largest proportion of publications and Australia had the highest citation ratio. Through the keyword analysis, the network identified 4 major research trends of corneal refractive surgery, penetrating keratoplasty, cataract surgery, and epidemiological surveys of astigmatism. "Photorefractive keratectomy," "postoperative astigmatism" and "surgery" had significant burst strength and continuous attention to the astigmatism vector analysis.
    Conclusion: Vector analysis is the most commonly used method to evaluate astigmatism and could significantly improve the accuracy of astigmatism correction, particularly in areas of refractive and cataract surgery. The application of vector analysis is beneficial in guiding the design of surgical incisions, determining the nomogram, optimizing the surgical protocol, and improving the accuracy of astigmatism correction. Meanwhile, the popularization of vector method will help to improve the accuracy of astigmatism analysis and promote the benign development of public health.
    Keywords:  astigmatism; bibliometric analysis; public health; surgery; vector method
    DOI:  https://doi.org/10.3389/fmed.2025.1519487
  16. Odontology. 2025 Apr 28.
    A scientometric, visualization, and content analysis on surgical endodontics from inception to 2023.
    Violetta Chasoglou, Anastasios Katakidis, Anastasia Fardi, Konstantinos Kodonas, Nikolaos Economides.
      In persistent periapical lesions, periapical surgery may be considered an alternative treatment option to remove inflammatory and necrotic tissue from the periapical region, seal the apical root end, and promote tissue regeneration. The present scientometric analysis aims to analyze the scientific landscape in the field of surgical endodontics, identify research trends, and classify popular topics. A thorough literature search was conducted in the Web of Science and Scopus databases on 29 September 2023 to retrieve all articles related to surgical endodontics. The articles were analyzed with Biblioshiny software, and the following details were collected: publication titles & years, authors' names and affiliations, journals' metrics, citation counts, author keywords, the field of study, study design, and outcome. A total of 1988 publications concerning surgical endodontics from 1935 until September 2023 were identified and further analyzed. Sixty-two countries contributed to scientific production in this field and the USA was the most productive among them. Von Arx T. and the Journal of Endodontics was the most relevant author and journal, respectively. "Materials" was the most prevalent title term and "apicoectomy" was the most used keyword. The distribution of the scientific literature on surgical endodontics was as follows: 38.3% basic science, 15.8% reviews, 37.2% observational studies, and 8.7% clinical studies. Overall, 31% of the conducted research concerned the materials and 19% the techniques used in clinical practice. This bibliometric analysis describes the research landscape in surgical endodontics and converts the acquired data into useful information regarding the current and future trends of this field.
    Keywords:  Apicoectomy; Bibliometrics; Periapical surgery; Scientometric analysis; Surgical endodontics
    DOI:  https://doi.org/10.1007/s10266-025-01114-4
  17. Front Surg. 2025 ;12 1511055
    Bibliometric analysis of hypospadias from 1998-2023.
    Dezhi Su, Xiaowei Li, Sha Li, Kun Wang, Gangquan Wu, Guomin Zhai.
       Introduction: To analyze the development trends and research hotspots in the field of hypospadias through bibliometric analysis.
    Methods: Utilizing three bibliometric mapping tools-bibliometrix R package, VOSviewer, and CiteSpace, we summarized the overview information of the retrieved literature. We conducted analyses on the co-occurrence and development trends of authors, institutions, countries, and keywords.
    Results: A total of 3,647 hypospadias-related publications were included, with contributions from 14,633 authors. The keyword co-occurrence network identified seven clusters related to the diagnosis, pathophysiology, and treatment of hypospadias. Researchers have primarily focused on the genetic mechanisms of hypospadias, the role of environmental factors, surgical outcomes, anesthesia techniques, and patient satisfaction post-surgery. Emerging research hotspots include the precise selection of surgical flap sources, genomic alterations, and the correlation with syndromes related to disorders of sex development, all of which show strong potential for future breakthroughs.
    Discussion: Bibliometric analysis provides a comprehensive understanding of the research hotspots and development trends in hypospadias, thereby enriching the field of hypospadias research.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; bibliometrix R package; hypospadias
    DOI:  https://doi.org/10.3389/fsurg.2025.1511055
  18. Front Microbiol. 2025 ;16 1569241
    Bibliometric analysis of research trends and prospective directions of Akkermansia muciniphila from 2010 to 2024.
    Yanan Wang, Jiahui He, Simin Chen, Xinyi Lv, Jiayi Chen, Kaiyue Ru, Xiao Liang, Meng Mao, Yuehan Song.
       Background: Akkermansia muciniphila (A. muciniphila) is an emerging probiotic with potential impact on human health, and there is a growing interest in this area, but an overall analysis of research trends is lacking. This study conducted a detailed bibliometric analysis and visualization of A. muciniphila research to examine the current research status, hotspots, and trends, aiming to inform future research directions.
    Methods: This study utilized the Web of Science database to search research on A. muciniphila from 2010 to 2024. Bibliometric analysis was conducted using CiteSpace and VOSviewer software to generate yearly publication trends, contributions by countries, institutions, and distinguished researchers, as well as key themes and influential researches. This analysis aimed to visualize and explore the literature over the past 15 years, guiding future researches and identifying gaps in the field of intestinal flora in A. muciniphila.
    Results: We searched a total of 4,423 related publications. Wei Chen, Willem de Vos and Patrice D. Cani are the primary contributors to A. muciniphila 's research. The top contributing countries and institutions are China, the United States, South Korea, Spain, and Italy, with research centers such as the Chinese Academy of Sciences, Zhejiang University, the University of Copenhagen, and the University of Helsinki being the main contributors. Current research hotspots focus on the molecular biology of A. muciniphila, such as its role in intestinal barrier maintenance, immune response, and its potential for regulating and treating digestive and metabolic diseases, such as cancer, fatty liver disease, inflammatory bowel disease, etc., through bile acid metabolism, extracellular vesicles, and insulin resistance.
    Conclusion: Our study synthesizes current research on A. muciniphila in various disease areas and suggests enhancing collaboration among countries, institutions, and authors to advance A. muciniphila-related clinical and basic research, explore its efficacy in a variety of diseases and the effects of commonly used clinical medications on A. muciniphila, to fill the research gaps in the current field, and to provide valid evidence for the development of A. muciniphila as a novel probiotic supplement.
    Keywords:  A. muciniphila; bibliometrics; frontiers; gut flora; visual analysis
    DOI:  https://doi.org/10.3389/fmicb.2025.1569241
  19. Ann Plast Surg. 2025 May 01. 94(5S Suppl 3): S417-S420
    The Impact of Women-Led Academic Collaborations in Plastic Surgery.
    Tiffany Jeong, Nicolás M Kass, Hilary Y Liu, Angel Dixon, Nia Buckner, José Antonio Arellano, Vu T Nguyen, Francesco M Egro, Jesse A Goldstein, Carolyn De La Cruz.
       INTRODUCTION: Gender parity in overall academic productivity in plastic surgery has increased, likely driven by the greater proportion of women in plastic surgery residency. Given the crucial role of collaboration in research productivity and securing grant funding, it becomes imperative to investigate whether gender disparities affect collaboration for female authors in plastic surgery. In this study, we explore how gender influences academic collaboration among plastic surgeons, according to impact factor (IF), overall rates of collaboration, and the departments with which they collaborate.
    METHODS: PubMed was queried for all articles from academic plastic surgery programs between 2018 and 2023. Collaborative articles were defined as a plastic surgery senior author with at least one author who was not from the same plastic surgery department. The senior author affiliation was used to select articles from academic plastic surgery departments. The first and senior author's gender were determined using Gender-API, a validated approach to assigning gender based on first name. Associations with gender and research impact variables were assessed, including publishing journals and their IF. Gender predominance in a collaborating specialty was determined by the AAMC 2021 Physician Specialty Data Report.
    RESULTS: A total of 21,068 articles were initially retrieved, 14,590 articles were reviewed after removal of duplicates, and 6525 articles qualified for inclusion. Gender-API was able to identify 98% of authors as male or female. A total of 17.2% of publications were led by female authors and 38.3% had a female first author (χ2 = 691.21, P < 0.0001). The proportions engaging in collaboration were similar, 18.3% and 37.9%, respectively. While female senior authors in plastic surgery have fewer publications (3.83 ± 7.31 vs 5.88 ± 11.1, P < 0.001) we found that the average journal IF was significantly greater in female-led articles (3.84 ± 6.11 vs 3.35 ± 4.60, P = 0.009) than in male led articles.Female senior authors were more likely to publish collaborations with specialties that had a higher proportion of women (χ2 = 5.30, P = 0.021); for example, 2.86% (n = 1) of collaborations with cardiothoracic surgery were with women (odds ratio = 0.130, P = 0.0138) and 35.6% (n = 5) of collaborations with endocrinology were with women (odds ratio = 2.38, P = 0.155).
    CONCLUSIONS: We demonstrate the nuanced effect of collaboration on research productivity for female authors in plastic surgery. In particular, female plastic surgery senior authorship and overall collaboration coincides with the gender proportions in the field. Furthermore, female senior authors in plastic surgery published in significantly higher IF journals. Lastly, our work implies that female in-group networks of academic collaborations may serve a vital role in the professional connections for women in the predominately male field of plastic surgery. Future studies may compare these data to the plastic surgery articles published in earlier years.
    Keywords:  academic productivity; collaboration; gender
    DOI:  https://doi.org/10.1097/SAP.0000000000004277
  20. J Nurs Manag. 2025 ;2025 5950542
    A Bibliometric Review of Publications on Innovative Behaviors of Nurse Managers.
    Nurcan Bi Lgi N, Damla Şahi N Büyük, Sevgi Paki Ş Çeti N.
      Aim: This study used bibliometric indicators to provide an overview of research on nurse managers' innovative behaviors. Background: Encouraging nurses' innovative abilities leads to improved care quality and work efficiency and reduced healthcare costs. For these reasons, the innovative behaviors of nurse managers are crucial for both their personal development and the success of their teams. Method(s): Bibliometric methods were employed to investigate the innovative behaviors of nurse managers. Data were collected from the Web of Science (WoS) database through mid-September 2024. A query string search yielded 478 articles, of which 44 met the inclusion criteria and were analyzed using bibliometric techniques. Microsoft Excel and the VOSviewer software were used to analyze the distribution of publications by year, leading countries, prominent journals, contributing authors, coauthor networks, and keyword co-occurrence. Results: There has been a recent increase in publications on the innovative behaviors of nurse managers, with the United States leading in publication output. The Journal of Nursing Management and the Journal of Nursing Administration were identified as the most prolific journals in this area. In the coauthorship analysis, nine authors emerged as the most linked, forming a cluster with a total of 36 links. Furthermore, the most used keywords were "nurses," "psychological empowerment," and "innovative behavior." Additionally, 56.8% of the articles employed quantitative methods, 31.8% used qualitative methods, and 11.4% applied mixed-method research designs. Conclusion(s): The analysis of articles indexed in the WoS database suggests that research on the innovative behaviors of nurse managers is still in its developmental stages. Implications for Nursing Managers: Future research should explore the innovative behaviors of nurse managers and the factors influencing these behaviors further. Both qualitative and quantitative studies should examine how and to what extent these behaviors impact the nurses under their supervision.
    Keywords:  VOSviewer; bibliometric analysis; innovative behavior; nurse managers; nursing
    DOI:  https://doi.org/10.1155/jonm/5950542
  21. World J Radiol. 2025 Apr 28. 17(4): 101636
    Structural and temporal dynamics analysis on immune response in low-dose radiation: History, research hotspots and emerging trends.
    Shu-Yuan Wang, Jia-Xing Wu, Xian An, Zhen Yuan, Yi-Fan Ren, Xiu-Feng Yu, Xiao-Dong Tian, Wei Wei.
       BACKGROUND: Radiotherapy (RT) is a cornerstone of cancer treatment. Compared with conventional high-dose radiation, low-dose radiation (LDR) causes less damage to normal tissues while potentially modulating immune responses and inhibiting tumor growth. LDR stimulates both innate and adaptive immunity, enhancing the activity of natural killer cells, dendritic cells, and T cells. However, the mechanisms underlying the effects of LDR on the immune system remain unclear.
    AIM: To explore the history, research hotspots, and emerging trends in immune response to LDR literature over the past two decades.
    METHODS: Publications on immune responses to LDR were retrieved from the Web of Science Core Collection. Bibliometric tools, including CiteSpace and HistCite, were used to identify historical features, active topics, and emerging trends in this field.
    RESULTS: Analysis of 1244 publications over the past two decades revealed a significant surge in research on immune responses to LDR, particularly in the last decade. Key journals such as INR J Radiat Biol, Cancers, and Radiat Res published pivotal studies. Citation networks identified key studies by authors like Twyman-Saint Victor C (2015) and Vanpouille-Box C (2017). Keyword analysis revealed hotspots such as ipilimumab, stereotactic body RT, and targeted therapy, possibly identifying future research directions. Temporal variations in keyword clusters and alluvial flow maps illustrate the evolution of research themes over time.
    CONCLUSION: This bibliometric analysis provides valuable insights into the evolution of studies on responses to LDR, highlights research trends, and identifies emerging areas for further investigation.
    Keywords:  Bibliometric analysis; Immune response; Immunotherapy; Low-dose radiotherapy; Radiation-induced immunogenicity; Synergistic therapies
    DOI:  https://doi.org/10.4329/wjr.v17.i4.101636
  22. J Rehabil Med. 2025 Apr 29. 57 jrm42473
    Global research trends in aquatic exercise therapy for musculoskeletal disorders: a bibliometric analysis.
    Wei Guo, Xiaowei Feng, Weiping Du.
       OBJECTIVE: Aquatic exercise therapy has gained recognition as a valuable non-pharmacological intervention for managing musculoskeletal disorders. Despite the growing body of evidence supporting its efficacy, research on aquatic exercise therapy remains fragmented, with limited understanding of key trends, influential studies, and evolving themes within the field. This study aims to conduct a comprehensive bibliometric analysis to identify publication trends, key authors, and the evolution of research themes in aquatic exercise therapy for musculoskeletal disorders.
    METHODS: A total of 117 articles were selected based on predefined search terms and inclusion criteria, resulting in 3,985 citations, with an average of 35.9 citations per article and an H-index of 37.
    RESULTS: Publications surged between 2013 and 2024, accounting for 88.3% of total output. Peaks occurred in 2019 (n = 14) and 2022 (n = 368 citations). Key contributors include Mariana Arias Avila and Basia Belza, with journals such as BMC Musculoskeletal Disorders and Arthritis & Rheumatism-Arthritis Care & Research playing pivotal roles. Research trends shifted from disease-specific studies to broader quality-of-life outcomes, with keywords such as "rheumatoid arthritis", "balneotherapy", and "quality of life" emerging as focal points.
    CONCLUSION: The findings underscore the growing importance of aquatic exercise therapy in clinical rehabilitation and suggest that future research should focus on long-term outcomes, underrepresented populations, and the integration of aquatic exercise therapy with emerging rehabilitation technologies.
    DOI:  https://doi.org/10.2340/jrm.v57.42473
  23. Gene. 2025 Apr 25. pii: S0378-1119(25)00321-X. [Epub ahead of print] 149533
    Mapping the research landscape of microRNA and stroke: a bibliometric analysis of insights, hotspots, and future directions.
    Loo Keat Wei, Chun Chong Fu, Saras Menon, Lyn R Griffiths.
      MicroRNAs (miRNAs) are critical regulators of stroke pathophysiology, influencing neuroinflammation, neuronal survival, and post-stroke recovery. This study presents a comprehensive bibliometric analysis of 1,988 miRNA-stroke research articles published over the past 42 years, mapping the intellectual landscape, emerging research hotspots, and future directions within the field. Using Python, VOSviewer, and CiteSpace, we identified influential studies, leading authors, collaborative networks, and key thematic clusters that are advancing research. Our analysis highlights several emerging hotspots, including exosomal miRNA biomarkers for stroke diagnosis, miRNA-based therapeutics, and regulatory networks involving circRNAs and lncRNAs, which present promising avenues for precision medicine. Citation burst and timeline analyses highlight the growing focus on miRNA-targeted interventions, epigenetic modifications, and neuroprotective strategies, which are rapidly shaping the evolution of stroke research. Importantly, we emphasize the need for increased research in human-based studies to validate these findings and ensure clinical applicability. This study provides a structured framework to guide future research efforts, promoting international collaboration and bridging the gap between fundamental discoveries and the clinical translation of miRNA-based diagnostics and therapeutics in stroke.
    Keywords:  Biomarkers; Human; Research Hotspot; Stroke; miRNA
    DOI:  https://doi.org/10.1016/j.gene.2025.149533
  24. Int J Environ Res Public Health. 2025 Mar 21. pii: 463. [Epub ahead of print]22(4):
    Global Trends in Diabetic Foot Research (2004-2023): A Bibliometric Study Based on the Scopus Database.
    Yolanda Fuentes-Peñaranda, Alma Labarta-González-Vallarino, Elena Arroyo-Bello, Marina Gómez de Quero Córdoba.
      Diabetic foot is one of the leading complications of diabetes mellitus that affects millions of people around the world and involves the presence of ulcers, infections, tissue destruction, and loss of sensation and can even lead to limb amputation. This research explores trends in diabetic foot global research through a bibliometric analysis of publications indexed in Scopus in the period 2004-2023. A total of 7136 documents were analysed using Excel, Python, Biblioshiny, and VOSviewer. Scientific production has multiplied by a factor of 6.6 from the first to the last year analysed. Armstrong D.G. is the most productive and cited author. China is the most productive country, and the United States is the most cited. The most productive journal is the International Journal of Lower Extremity Wounds, and the most cited journal is Diabetes Care. Research on diabetic foot is mainly focused on the complications of diabetes mellitus; the treatment and healing of wounds; infections; and epidemiology and patient care. Infections and antibiotic treatment are emerging topics, while deep learning and machine learning are among the niche topics in this area of knowledge. The present study allows us to identify current trends and future directions of research in diabetic foot.
    Keywords:  Scopus; bibliometric analysis; diabetic foot; research trends
    DOI:  https://doi.org/10.3390/ijerph22040463
  25. Front Nutr. 2025 ;12 1539587
    Obesity and psychology: a bibliometric analysis of half a century.
    Haiqiu Zhou, Shan Liu, Zixuan Xiao, Saiqiong Yin, Boyan Fan, Guixiang Sun.
       Background: The interaction mechanisms between obesity and psychological factors are intricate and bidirectional. Psychological issues can prompt unhealthy eating behaviors, impede weight management efforts, and elevate the risk of obesity. This study employs bibliometric approaches to conduct a comprehensive analysis of the knowledge structure, research hotspots, and development trends in the field of obesity and psychology, offering valuable references for future research in this area.
    Methods: This study draws on the Web of Science Core Collection (WoSCC) database, with "obesity" and "psychology" serving as the primary search terms. Leveraging CiteSpace (version 6.3.R1) and VOSviewer (version 1.6.20) software, bibliometric analyses were conducted on various indicators, including the number of publications, publication volume, authors, journals, references, countries, institutions, and keywords. Through co-citation analysis and keyword co-occurrence analysis, the research hotspots and developmental trajectories in this field were revealed.
    Results: Based on the inclusion and exclusion criteria, a total of 2,753 relevant articles were ultimately included in this study. The results indicate that since the 21st century, there has been a significant surge in the number of publications in the field of obesity and psychology. Developed countries like the United States, Canada, the United Kingdom, and Australia are at the forefront of this field. Leading research institutions include Yale University, University College London, and the University of Pennsylvania. Among the authors, GRILO CM has the highest publication output. Research hotspot keywords primarily include "depression," "stress," "emotional eating," "bariatric surgery," "intervention," "weight stigma," and "self-regulation." Current research trends reveal a marked regional imbalance in international collaboration in the field of obesity and psychology. In particular, there exists a notable absence of substantive cooperation between developed and developing countries. Research hotspots mainly center around the following aspects: Firstly, it focuses on the prevalence of common psychological distress symptoms, including depression, anxiety, and stress, within the obese population and the implications these symptoms have for health. Secondly, mental health issues like binge eating and emotional eating play a pivotal role in the onset and maintenance of obesity. Thirdly, psychosocial factors like health-related quality of life and weight stigma are at the core of obesity intervention and have potential impacts on behavioral change. Meanwhile, researchers are increasingly concentrating on the individualized mental health requirements of obese populations, emphasizing the importance of evidence-based psychological interventions in the management of obesity. These research hotspots not only enhance our understanding of the complex relationship between obesity and mental health but also provide crucial theoretical foundations and practical insights for future research directions.
    Conclusion: This study employs bibliometric approaches to conduct a comprehensive and in-depth analysis of research trends and developments in the field of obesity and psychology. The research reveals the current status and characteristics of this field from multiple perspectives, offering scientific backing for researchers to identify potential collaborators, pinpoint hotspot issues, and keep abreast of the latest developments. Looking forward to the future, related research can further expand data sources, diversify research viewpoints, and delve more profoundly into the complex relationship between obesity and mental health.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; obesity; psychology
    DOI:  https://doi.org/10.3389/fnut.2025.1539587
  26. Clin Exp Rheumatol. 2025 May 01.
    Research trends of the aetiology of systemic lupus erythematosus in the past 10 years: a bibliometric analysis (2014-2023).
    Yong-Long Yan, Ya-Shuang Su, Jing-Jing Cao, Jie Lin, Jun-Lie Sun, Cui-Fang Zhang, Rui-De Su.
       OBJECTIVES: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterised by a complex aetiology that encompasses genetic, environmental, and immunological factors. A comprehensive understanding of SLE aetiology is essential for the development of effective therapeutic strategies and the enhancement of patient outcomes. This study aims to provide a thorough bibliometric analysis of research concerning the aetiology of SLE conducted over the past decade.
    METHODS: A bibliometric analysis was conducted based on articles published between January 2014 and December 2023, retrieved from the Web of Science Core Collection database. The analysis employed the R package 'bibliometrix', as well as VOSviewer and CiteSpace.
    RESULTS: A total of 5,825 publications were analysed. The results underscore the global collaborative nature of SLE research, with significant contributions from China, the USA, and Japan. Notable institutions included Harvard University, the Chinese Academy of Medical Sciences, and the Egyptian Knowledge Bank. Influential journals in the field comprised Arthritis & Rheumatology, Annals of the Rheumatic Diseases, and Frontiers in Immunology. Key word analysis revealed a recent emphasis on terms such as 'management','efficacy', and 'safety', together with emerging interests in 'health' and 'genes'.
    CONCLUSIONS: This study provides a bibliometric analysis of SLE aetiology research, highlighting evolving research trends, influential studies, and collaborative networks. The findings indicate a shift in research focus from specific disease pathogenesis and expression toward genetic mechanisms, diagnostic approaches, and clinical applications. Future research on SLE aetiology is likely to prioritise investigations into DNA, genes, and validating existing findings.
    DOI:  https://doi.org/10.55563/clinexprheumatol/yvqg5k
  27. World J Psychiatry. 2025 Apr 19. 15(4): 104600
    Comprehensive bibliometric analysis of transcranial magnetic stimulation-based depression treatment from 2003 to 2022: Research hotspots and trends.
    Zheng-Yu Li, Yu-Wei Zhang, Hao-Ran Yang, Yu-Qing Ren, Hong-Jin Wu, Meng-Yun Zhang, Song Zhang, Ying-Fu Jiao, Wei-Feng Yu, Jie Xiao, Po Gao, Heng Yang.
       BACKGROUND: Depression has become a global public health problem. In recent years, transcranial magnetic stimulation (TMS) has gained considerable attention as a non-invasive treatment for depression.
    AIM: To investigate the research hotspots and trends in the field of TMS-based depression treatment from a bibliometric perspective.
    METHODS: Using the Web of Science Core Collection, articles published between 2003 and 2022 on TMS-based depression treatment were retrieved from the science citation index expanded. The publication trends and research hotspots were analyzed using VOSviewer, CiteSpace, and the bibliometric online analysis platform. Regression analysis was performed using Microsoft Excel 2021 to predict publication growth trends.
    RESULTS: We identified a total of 702 articles on TMS-based depression treatment with a predominance of clinical studies. Analysis of collaborative networks showed that the United States, the University of Toronto, and Daskalakis ZJ were identified as the most impactful country, institution, and researcher, respectively. In keyword burst analysis, it was found that theta burst stimulation (TBS), functional connectivity, and frequency were the most recent research hotspots.
    CONCLUSION: TMS provides a novel therapeutic option for patients with treatment-resistant depression. Neuroimaging technology enables more precise TMS treatment, while the novel TMS modality, TBS, enhances both therapeutic efficacy and patient experience in TMS-based depression treatment. The integration of neuroimaging techniques with TBS represents a promising research direction for advancing TMS-based depression treatment. This study presents systematic information and recommendations to guide future research on TMS-based depression treatment.
    Keywords:  Bibliometric analysis; Depression; Theta burst stimulation; Transcranial magnetic stimulation; Transcranial magnetic stimulation-based depression treatment
    DOI:  https://doi.org/10.5498/wjp.v15.i4.104600
  28. Polymers (Basel). 2025 Apr 21. pii: 1124. [Epub ahead of print]17(8):
    Trends and Future Projections in Ultrasonic Welding Research for Hybrid Materials.
    Jedaías J Silva, Rafael G C da Silva, Carolina L Morelli, Edwar A T López, Tiago F A Santos.
      Ultrasonic welding has gained interest from various researchers and industries worldwide, particularly for joining dissimilar materials in sectors such as aerospace, aeronautics, and electronics. This paper presents a comprehensive bibliometric review aimed at mapping the evolving landscape of ultrasonic welding research. Through the systematic analysis of 1913 scientific documents, it identifies key advances, challenges, and future directions in the field. Furthermore, the bibliometric analysis sheds light on annual scientific production, prolific authors and institutions, scientific contribution per country, and methodological approaches. The global collaboration network comprises countries from all continents, with a prominent presence in Europe, Asia, and the Americas and less representation from African and Oceanian countries. China and the United States dominate the field in terms of scientific document production, international collaborations, and citations, with Germany also standing out for leading the number of citations in research related to hybrid metal/polymer joining. This review aims to serve as a valuable resource for researchers, practitioners, and policymakers interested in the advancements and future directions of ultrasonic welding for hybrid materials.
    Keywords:  Scopus; Web of Science; aluminum; composite; joining; reinforced polymer; ultrasonic welding
    DOI:  https://doi.org/10.3390/polym17081124
  29. World J Gastrointest Surg. 2025 Apr 27. 17(4): 102020
    Visualizing global progress and challenges in esophagogastric variceal bleeding.
    De-Xin Wang, Xue-Jie Wu, Jin-Zhong Yu, Jun-Yi Zhan, Fei-Fei Xing, Wei Liu, Jia-Mei Chen, Ping Liu, Cheng-Hai Liu, Yong-Ping Mu.
       BACKGROUND: Esophageal and gastric variceal bleeding is a catastrophic complication of portal hypertension, most commonly caused by cirrhosis of various etiologies. Although a considerable body of research has been conducted in this area, the complexity of the disease and the lack of standardized treatment strategies have led to fragmented findings, insufficient information, and a lack of systematic investigation. Bibliometric analysis can help clarify research trends, identify core topics, and reveal potential future directions. Therefore, this study aims to use bibliometric methods to conduct an in-depth exploration of research progress in this field, with the expectation of providing new insights for both clinical practice and scientific research.
    AIM: To evaluate research trends and advancements in esophagogastric variceal bleeding (EGVB) over the past twenty years.
    METHODS: Relevant publications on EGVB were retrieved from the Web of Science Core Collection. VOSviewer, Pajek, CiteSpace, and the bibliometrix package were then employed to perform bibliometric visualizations of publication volume, countries, institutions, journals, authors, keywords, and citation counts.
    RESULTS: The analysis focused on original research articles and review papers. From 2004 to 2023, a total of 2097 records on EGVB were retrieved. The number of relevant publications has increased significantly over the past two decades, especially in China and the United States. The leading contributors in this field, in terms of countries, institutions, authors, and journals, were China, Assistance Publique-Hôpitaux de Paris, Bosch Jaime, and World Journal of Gastroenterology, respectively. Core keywords in this field include portal hypertension, management, liver cirrhosis, risk, prevention, and diagnosis. Future research directions may focus on optimizing diagnostic methods, personalized treatment, and multidisciplinary collaboration.
    CONCLUSION: Using bibliometric methods, this study reveals the developmental trajectory and trends in research on EGVB, underscoring risk assessment and diagnostic optimization as the core areas of current focus. The study provides an innovative and systematic perspective for this field, indicating that future research could center on multidisciplinary collaboration, personalized treatment approaches, and the development of new diagnostic tools. Moreover, this work offers practical research directions for both the academic community and clinical practice, driving continued advancement in this domain.
    Keywords:  Bibliometrics; Esophagogastric variceal bleeding; Liver cirrhosis; Non-cirrhotic portal hypertension; Portal hypertension; Visualization
    DOI:  https://doi.org/10.4240/wjgs.v17.i4.102020
  30. BMJ Open. 2025 May 02. 15(5): e101169
    Role of artificial intelligence in early identification and risk evaluation of non-communicable diseases: a bibliometric analysis of global research trends.
    Arwa M Al-Dekah, Waleed Sweileh.
       OBJECTIVE: This study aims to shed light on the transformative potential of artificial intelligence (AI) in the early detection and risk assessment of non-communicable diseases (NCDs).
    STUDY DESIGN: Bibliometric analysis.
    SETTING: Articles related to AI in early identification and risk evaluation of NCDs from 2000 to 2024 were retrieved from the Scopus database.
    METHODS: This comprehensive bibliometric study focuses on a single database, Scopus and employs narrative synthesis for concise yet informative summaries. Microsoft Excel V.365 and VOSviewer software (V.1.6.20) were used to summarise bibliometric features.
    RESULTS: The study retrieved 1745 relevant articles, with a notable surge in research activity in recent years. Core journals included Scientific Reports and IEEE Access, and core institutions included the Harvard Medical School and the Ministry of Education of the People's Republic of China, while core countries comprised China, the USA, India, the UK and Saudi Arabia. Citation trends indicated substantial growth and recognition of AI's impact on NCDs management. Frequent author keywords identified key research hotspots, including specific NCDs like Alzheimer's disease and diabetes. Risk assessment studies demonstrated improved predictions for heart failure, cardiovascular risk, breast cancer, diabetes and inflammatory bowel disease.
    CONCLUSION: Our findings highlight the increasing role of AI in early detection and risk prediction of NCDs, emphasising its widening research impact and future clinical potential.
    Keywords:  Artificial Intelligence; Health; Machine Learning; Medicine
    DOI:  https://doi.org/10.1136/bmjopen-2025-101169
  31. Front Oncol. 2025 ;15 1529297
    Mapping the knowledge domains of literature on hepatocellular carcinoma and liver failure: a bibliometric approach.
    Jun Pu, Yamin Zhao, Siming Zhang, Tianqi Wu, Ruizi Liu, Tianyi Yuan, Songnian He, Qingyu Hao, Haixia Zhu.
       Background: Hepatocellular carcinoma (HCC) accounts for 75-85% of primary liver cancers, with its incidence continually rising, posing a threat to socio-economic development. Currently, liver resection is the standard treatment for HCC. However, post-hepatectomy liver failure (PHLF) is a severe and formidable postoperative complication that increases patients' medical expenses and mortality risk. Additionally, liver failure can occur at any stage of HCC development, severely affecting patients' quality of life and prognosis.
    Method: Using the Web of Science Core Collection, this bibliometric study analyzed English articles and reviews on HCC and liver failure from 2003 to 2023. Bibliometric tools like CiteSpace, VOSviewer, and R-studio were employed for data visualization and analysis, focusing on publication trends, citation metrics, explosive intensity, and collaborative networks. Use the Comparative Toxicogenomics and Genecards databases to screen for genes related to liver failure, and perform enrichment analyses using Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and PubMed on the identified differentially expressed genes.
    Results: The study identified a significant increase in publications on HCC and liver failure, with key contributions from journals such as the World Journal of Gastroenterology and the Journal of Hepatology. The United States, China, and Japan were the leading countries in research output. Prominent authors and institutions, including Kudo Masatoshi and Sun Yat-sen University, were identified. Enrichment analysis showed drug metabolism, oxidative stress, lipid metabolism, and other pathways are closely related to this field. Research hotspots included risk prediction models and novel therapies.
    Conclusion: This bibliometric analysis highlights the growing research interest and advancements in HCC and liver failure. Future research should focus on improving risk prediction, developing new therapies, and enhancing international collaboration to address these critical health issues.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; hepatocellular carcinoma; liver failure
    DOI:  https://doi.org/10.3389/fonc.2025.1529297
  32. J Health Popul Nutr. 2025 Apr 29. 44(1): 142
    Research trajectory of the mechanism of preeclampsia: a scientometric perspective.
    Shen Li, Meiling Sun, Datong Liu, Xuanyi Wang.
       OBJECTIVE: This study aims to conduct a scientometric analysis on the research history and emerging trends of the pathogenesis of preeclampsia using CiteSpace and VOSviewer software. The goal is to provide guidance for future research and clinical practice.
    METHODS: The core collection database of Web of Science was searched for research literature on the mechanism of preeclampsia from January 1980 to March 2024. CiteSpace6. 1. R6, 5. 7. R5 (64-bit), and VOSviewer1.6.19 software were used for visual analysis, including networks of keywords, countries, authors, institutions, funds, and fields.
    RESULTS: A total of 4989 documents were analyzed in this study. The number of published articles has shown a consistent increase from 1990 to 2022, indicating that this topic remains a significant area of research. The countries, institutions, authors, journals, and fields that contributed the most articles include the USA, University of Mississippi, Lamarca, Babbette, Placenta, and the field of OBSTETRICS and GYNECOLOGY. Keyword clustering and emergence analysis identified 7 clusters, while clustering and emergence analysis of cited documents identified 14 clusters. These analyses revealed that current research on the mechanism of preeclampsia primarily focuses on placental ischemia and hypoxia, inflammatory response and immune disorders, angiogenic factor imbalance, abnormal epigenetic modifications, and intestinal flora imbalance.
    CONCLUSIONS: Research on the mechanisms of preeclampsia is rapidly advancing. Given the presence of multiple mechanisms and pathways, further collaborative research is essential to guide clinical treatment effectively and enhance maternal and child outcomes.
    Keywords:  CiteSpace; Pathogenesis; Preeclampsia; Scientometrics; VOSviewer; Visual analysis
    DOI:  https://doi.org/10.1186/s41043-025-00806-5
  33. Bioengineering (Basel). 2025 Mar 28. pii: 347. [Epub ahead of print]12(4):
    Novel Tissue Engineering Scaffolds in the Treatment of Spinal Cord Injury-A Bibliometric Study.
    Yan Zhao, Abudunaibi Aili, Zhiwei Jia, Tianlin Wen, Aikeremujiang Muheremu.
       OBJECTIVE: Because of the evolving nature of tissue engineering scaffolds in the treatment of spinal cord injury (SCI), the current study was carried out to evaluate the research productivity of tissue engineering scaffolds in the treatment of SCI.
    METHODS: Studies published from 2000 to 2025 were retrieved from the Web of Science core collection with topics of spinal cord injury and tissue engineering scaffolds. The data were analyzed and visualized using the VOSviewer network analysis software.
    RESULTS: Among 1542 articles analyzed, annual publications surged from 2000 to 2019, stabilizing thereafter. The U.S., China, and Canada led in productivity, with Northwestern University and the Biomaterials journal being top contributors. Keyword analysis revealed research hotspots such as functional recovery, axonal regeneration, stem cells, and hydrogels. Notably, hydrogels embedded with genetically engineered cells emerged as a pivotal trend, reflecting a shift toward biomimetic and combinatorial therapies. Collaboration networks highlighted intensified partnerships between Chinese and North American institutions, signaling global interdisciplinary efforts.
    CONCLUSIONS: This study provides the first bibliometric roadmap for tissue engineering scaffolds in SCI, identifying key trends, influential entities, and underexplored areas. The rise in hydrogels and international collaborations underscores opportunities for targeted research. These findings guide researchers in prioritizing high-impact journals, fostering partnerships, and advancing novel scaffold designs to bridge translational gaps in SCI treatment.
    Keywords:  axonal regeneration; bibliographic study; cell transplantation; hydrogels; spinal cord injury; tissue engineering
    DOI:  https://doi.org/10.3390/bioengineering12040347
  34. Healthcare (Basel). 2025 Apr 13. pii: 892. [Epub ahead of print]13(8):
    Global Research Trends, Hotspots, Impacts, and Emergence of Artificial Intelligence and Machine Learning in Health and Medicine: A 25-Year Bibliometric Analysis.
    Alaa Dalky, Mahmoud Altawalbih, Farah Alshanik, Rawand A Khasawneh, Rawan Tawalbeh, Arwa M Al-Dekah, Ahmad Alrawashdeh, Tamara O Quran, Mohammed ALBashtawy.
      Background/Objectives: The increasing application of artificial intelligence (AI) and machine learning (ML) in health and medicine has attracted a great deal of research interest in recent decades. This study aims to provide a global and historical picture of research concerning AI and ML in health and medicine. Methods: We used the Scopus database for searching and extracted articles published between 2000 and 2024. Then, we generated information about productivity, citations, collaboration, most impactful research topics, emerging research topics, and author keywords using Microsoft Excel 365 and VOSviewer software (version 1.6.20). Results: We retrieved a total of 22,113 research articles, with a notable surge in research activity in recent years. Core journals were Scientific Reports and IEEE Access, and core institutions included Harvard Medical School and the Ministry of Education of the People's Republic of China, while core countries comprised the United States, China, India, the United Kingdom, and Saudi Arabia. Citation trends indicated substantial growth and recognition of AI's and ML impact on health and medicine. Frequent author keywords identified key research hotspots, including specific diseases like Alzheimer's disease, Parkinson's diseases, COVID-19, and diabetes. The author keyword analysis identified "deep learning", "convolutional neural network", and "classification" as dominant research themes. Conclusions: AI's transformative potential in AI and ML in health and medicine holds promise for improving global health outcomes.
    Keywords:  artificial intelligence; health; machine learning; medicine
    DOI:  https://doi.org/10.3390/healthcare13080892
  35. Digit Health. 2025 Jan-Dec;11:11 20552076251335707
    Global trends in internet hospitals and electronic prescriptions: Insights for China.
    Kang Luo, Chengyu Sun, Furong Yu, Xiaoxia He, Yi Feng, Wensheng Zhu, Xue Yang.
       Objectives: This study aims to review the research status of Internet hospitals and electronic prescriptions, identify associated research hotspots and frontiers, understand global application progress, and inform future research and development directions in China.
    Methods: The literature was obtained via the online Science Citation Index-Expanded section of the Web of Science Core Collection (WoSCC). The search terms included variations of "Internet hospital" and "electronic prescription." After screening titles and abstracts, 248 publications were selected. CiteSpace was used for bibliometric and visual analysis, identifying annual publication trends, collaboration networks, and keywords with strong citation bursts.
    Results: The analysis revealed fluctuating growth in annual publications, with a significant increase in the 2020s due to COVID-19. In the domain under analysis, the US and Harvard Medical School emerged as the most prominent contributors, high-frequency keywords identified were patient safety, digital health, healthcare management, and prevalence. Key findings indicated active cooperation among institutions within the USA or Europe but limited collaboration between USA, Europe, and Asia. Internet hospitals and electronic prescriptions were found to significantly enhance patient safety and healthcare quality during public health emergencies.
    Conclusions: The research identified a lack of effective collaboration among nations, organizations, and contributors, with primary trends focusing on patient safety, digital health, healthcare management, and prevalence. Researchers in China are encouraged to focus on how Internet hospital electronic prescribing can improve patient safety, assist in the health management of special populations, and leverage their strengths during large epidemics.
    Keywords:  CiteSpace; Internet hospitals; bibliometrics; electronic prescriptions; visualization analysis
    DOI:  https://doi.org/10.1177/20552076251335707
  36. Urology. 2025 Apr 30. pii: S0090-4295(25)00400-5. [Epub ahead of print]
    Gender Authorship Among Urology Artificial Intelligence Publications: A 10-Year Retrospective Analysis.
    Gillian Murray, Ranveer M S Vasdev, Luqman Ellythy, Tianyu He, Anish Sethi, Meghan Cooper, Sevann Helo, Candace F Granberg, Abhinav Khanna, Stephen A Boorjian, Katherine Anderson.
      We aim to characterize gender authorship in urology-related artificial intelligence (AI) research. A retrospective review was performed using MEDLINE, Embase®, and Web of Science (Clarivate™) databases (2014-2024). First and senior author gender was estimated using Gender API©. Of 799 urology related- AI research articles, 17.6% of first authors and 12.5% of senior authors were female. The proportion of female authors in urology-specific journals was lower compared to males (p<0.05). Publication impact factor was significantly lower among female senior authors (p <0.05). Gender disparities in urology-related AI research exist. Future work aims to employ and assess strategies to encourage greater female representation.
    DOI:  https://doi.org/10.1016/j.urology.2025.04.044
  37. Clin Rheumatol. 2025 Apr 30.
    A bibliometric analysis of rheumatology: knowledge structure and research trends of RNA-Binding proteins in rheumatic diseases.
    Wei Zhang, Jiaqi Song, Shuyuan Xian, Sujie Xie, Yifan Liu, Yuntao Yao, Xirui Tong, Xinru Wu, Yuanan Li, Haoyu Zhang, Bingnan Lu, Jiajie Zhou, Yibin Zhou, Dayuan Xu, Runzhi Huang, Shizhao Ji.
       BACKGROUND: Rheumatic disease is a kind of disease dominated by inflammatory lesions of connective tissue and abnormal immune function. It mostly belongs to autoimmune diseases or connective tissue diseases affecting multiple organs. Meanwhile, understanding the role of RNA-binding proteins (RBPs) in pathogenesis is rapidly developing. This study aims at summarizing the hotspots in rheumatology studies related to RBPs.
    METHODS: Scientific papers on RBPs related to rheumatology between 1982 and 2022 were gathered from the Web of Science database. The data analysis and visualization were obtained using the Bibliometrix package. Bibliometrix package was used to analyze bibliometric indicators and visualize the trends and hotspots of the research.
    RESULTS: A total of 964 articles met the requirement. From 1982 to 2022, the USA and Anhui Medical University were the most productive country and institution, respectively, in this field. Arthritis and Rheumatism, Annals of the Rheumatic Diseases and Arthritis & Rheumatology were the top three periodicals obtained by Bradford's law. Co-word analysis divided the keywords into three clusters, focusing on diagnosis and classification of Systemic Lupus Erythematosus, pathogenesis of osteoarthritis and pathogenesis of Rheumatoid Arthritis, respectively. Trend topic analysis revealed that pathogenesis and classification of rheumatic diseases might be the research trend.
    CONCLUSION: Focusing on RBPs in rheumatic diseases, we illustrated the evolution of this field and predicted future research hotspots. The research trend topics have evolved towards clinical classification and pathogenesis at the molecular and genetic level. The pathogenic mechanism in rheumatic diseases will continue to be a hotspot in the future. Besides, the classification of Systemic Lupus Erythematosus patients may be another hotspot. Researchers are recommended to pay more attention to hotspots demonstrated in the future. Key Points • Bibliometrix package was used to analyze bibliometric indicators and visualize the trends and hotspots of the research. • Focusing on RBPs in rheumatic diseases, we illustrated the evolution of this field and predicted future research hotspots. • The research trend topics have evolved towards clinical classification and the pathogenesis at the molecular and genetic level. • The pathogenic mechanism in rheumatic diseases will continue to be a hotspot in the future.
    Keywords:  Bibliometrics; RNA-binding proteins (RBPs); Rheumatic diseases; Rheumatology
    DOI:  https://doi.org/10.1007/s10067-025-07403-1
  38. Digit Health. 2025 Jan-Dec;11:11 20552076251336940
    Research landscape and trends of internet addiction disorder: A comprehensive bibliometric analysis of publications in the past 20 years.
    Xiaodong Cheng, Yan Fan, Sen Li, Xiao Li, Shushu Jin, Cong Zhou, Yu Feng.
       Background: Internet addiction disorder (IAD) has emerged as a significant public health concern in the digital age, with implications for mental health and social wellbeing. Despite growing recognition, IAD remains a relatively nascent field within academic research.
    Methods: We conducted a comprehensive bibliometric analysis to explore the global research landscape and trends of IAD. Our methodology involved analyzing author analysis, journal analysis, keywords, and citations in publications related to IAD from 2004 to 2024.
    Results: We identified "internet addiction," "internet gaming disorder," and "adolescent" as the most frequently occurring keywords, highlighting significant research areas within IAD. The analysis revealed that terms like "social media addiction," "problematic smartphone use," and "COVID-19" have gained prominence in recent years, reflecting the evolving nature of digital technology's impact on mental health. Clustering analysis illustrated the interdisciplinary nature of IAD research, integrating insights from psychology, sociology, network science, and psychiatry. Citation analysis identified highly influential papers, such as Kuss and Griffiths' review on social networking addiction and Brand et al.'s I-PACE model for internet-use disorders.
    Conclusions: Our findings highlighted the importance of continuing interdisciplinary research to address the multifaceted challenges of IAD. Future research should focus on the intersections of digital behaviors with mental health, personality traits, and social dynamics to develop comprehensive strategies for prevention and intervention.
    Keywords:  Internet addiction disorder; bibliometric analysis; internet gaming disorder; mental health; problematic smartphone use; social media addiction
    DOI:  https://doi.org/10.1177/20552076251336940
  39. Front Hum Neurosci. 2025 ;19 1574721
    Research hotspots and frontiers of neuromodulation technology in the last decade: a visualization analysis based on the Web of Science database.
    Yanpei Liu, Qian Zhang, Haoran Zhang, Yun Xiang, Hui Wang.
       Background: Since the 1990s, neuromodulation technology has experienced rapid advancements, providing new therapeutic approaches for clinical rehabilitation in neurological disorders. The objective of this study is to utilize CiteSpace and VOSviewer to investigate the current research status, key topics, and future trends in the field of neuromodulation technology over the past decade.
    Methods: Relevant literature in the field of neuromodulation technology published in Web of Science database from January 1, 2014 to June 18, 2024 were retrieved, and imported into CiteSpace and VOSviewer for visualization. VOSviewer was used for counties, institutions, authors and keywords analyses. CiteSpace was used for presentation visualization analysis of co-cited references, keywords clusters and bursts.
    Results: This study encompasses a total of 1,348 relevant publications, with the number of publications showing an increasing trend year by year. The most significant growth was observed between 2020 and 2021. The United States, China and the United Kingdom are the three leading countries with high output in this regard. The top three institutions in terms of the publication volume are Harvard Medical School, the University of Toronto and Stanford University. Keyword co-occurrence and cluster analysis identified that deep brain stimulation, transcranial magnetic stimulation, transcranial direct current stimulation, and focused ultrasound stimulation are the most widely used central nerve stimulation techniques in neuromodulation. The treatment of intractable chronic pain also emerged as a key focus within neuromodulation techniques. The recent keywords bursts included terms such as recovery, movement, nucleus, modeling and plasticity, suggesting that the future research trend will be centered on these areas.
    Conclusion: In conclusion, neuromodulation technology is garnering increasing attention from researchers and is currently widely used in brain diseases. Future research is expected to delve deeper, particularly into exploring deep brain structure stimulation targets and restoring motor function based on neuroplasticity theory.
    Keywords:  bibliometrics; deep brain stimulation; neuromodulation; neuroplasticity; transcranial magnetic stimulation
    DOI:  https://doi.org/10.3389/fnhum.2025.1574721
  40. Adv Exp Med Biol. 2025 ;1469 207-243
    A Comprehensive Bibliometric Analysis of Orchitis Research from 1980 to 2023.
    Haoyang Qu, Qiubei Liu, Dongwang Zheng, Ya Ni, Xiang Xiao.
      Orchitis, an inflammation of the testes, presents significant implications for male fertility and has been a focal area of scientific inquiry over the past four decades. This study employs a comprehensive bibliometric analysis to assess the progression of global research on orchitis from 1980 to 2023. Drawing from a dataset of 1586 publications indexed in the Web of Science Core Collection, we uncover emerging patterns, collaborations, and pivotal works that have shaped the field. The United States, China, and Germany emerge as leading contributors, while the Journal of Urology stands out as a primary publishing avenue. The results highlight the increasing recognition of autoimmune responses, alongside infectious agents, as key contributors to orchitis. Moreover, molecules such as TNF-α, IL-6, and IFN-γ are identified as central to the disease's pathology. The dynamic interplay of testosterone and regulatory T cells is underscored as a determinant of the testicular immune milieu. Notably, disruptions in the blood-testis barrier (BTB) and germ cell apoptosis emerge as pivotal consequences of the condition. This analysis underscores the expansive and multidisciplinary nature of orchitis research, revealing a consistent growth in collaborative endeavors. In summary, our findings catalog the evolution of orchitis research, providing a consolidated perspective on past achievements and signposting future research avenues. Such insights are instrumental for researchers aiming to navigate the complexities of orchitis and its multifaceted impact on male reproductive health.
    Keywords:  Bibliometric analysis; Blood–testis barrier (BTB); Cytokines; Experimental autoimmune orchitis (EAO); Male reproductive health; Orchitis; Testicular immune privilege; Testicular inflammation
    DOI:  https://doi.org/10.1007/978-3-031-82990-1_10
  41. Trop Anim Health Prod. 2025 Apr 30. 57(4): 201
    A bibliometric mapping of advancements and trends in genome editing in pigs.
    Jaya Bharati, Satish Kumar, Salam Jayachitra Devi, Vivek Kumar Gupta.
      Researchers have widely undertaken targeted genome editing in pigs to optimize pig productivity, disease tolerance and for biomedical research. The present study aimed to investigate research advancements, focus areas, gaps, and challenges in genome editing in pigs using bibliometric analysis. The bibliographic information of publications on genome editing in pigs from 2010 to 2023 was retrieved from the Scopus database. Bibliometric parameters, such as coauthorship, keyword co-occurrence, citation, bibliographic coupling, and cocitation, was analyzed using VOSviewer. Literature mining was conducted to evaluate the emerging areas and challenges in the development of genome-edited pigs. We found 725 documents on genome editing in pigs, 407 of which were research articles authored by 2826 researchers from 1359 research organizations across 40 countries. The two countries, China and the United States, account for more than 50% of the research publications on genome editing in pigs. Investigations on the optimization of the procedure, delivery methods, editing efficiency, and reducing off-target effects dominated the early phase of research, which has shifted to its application for generating knockout (KO) or knockin (KI) pigs in recent years. Areas such as xenotransplantation, disease resistance, higher muscling, and disease models have dominated the research horizon for genome editing in pigs. Emerging areas in gene editing include base editing, CRISPR-based screens, diagnostics, and therapeutics. However, investigations on reducing heat stress and environmental footprint through genetic alterations need more attention from scientists. Challenges such as off-target effects and regulatory, ethical and societal issues related to channelizing gene-edited pigs from lab to land and then from farm to fork continue to restrain this field.
    Keywords:  Bibliometric; CRISPR; Disease resistance; Genome editing; Knockout; Pig; Research trend; Xenotransplantation
    DOI:  https://doi.org/10.1007/s11250-025-04432-5
  42. Front Immunol. 2025 ;16 1566227
    A bibliometric and visual analysis of the impact of senescence on tumor immunotherapy.
    Zixu Liu, Yuchen Mao, Shukai Wang, Haoyu Zheng, Kangping Yang, Liang Yang, Peng Huang.
       Background: Recently, many studies have focused on the relationship between senescence and immunotherapy in cancer treatment. However, relatively few studies have examined the intrinsic links between the three. Whether these studies can act synergistically in the fight against cancer and the specific links between them are still unclear.
    Methods: We extracted, quantified, and visualized data from the literature (n = 2396) for the period 2004-2023 after rigorous quality control using citespace, GraphPad Prism, the R software package, and VOSviewer.
    Results: Linear fit analyses were generated to predict the number of annual publications and citations as a function of the top-performing authors, journals, countries, and affiliations academically over the past two decades such as Weiwei, Aging-us, China, and the UT MD Anderson Cancer Center. Vosviewer-based hierarchical clustering further categorized study characteristics into six clusters, including two major clusters of immunotherapy research, immunosenescence-related research factors, and timeline distributions suggesting that cellular senescence and tumor progression is a relatively new research cluster that warrants further exploration and development. Study characterization bursts and linear regression analyses further confirmed these findings and revealed other important results, such as aging (a = 1.964, R² = 0.6803) and immunotherapy (a = 16.38, R² = 0.8812). Furthermore, gene frequency analysis in this study revealed the most abundant gene, APOE, and SIRT1-7 proteins.
    Conclusion: The combination of aging therapies with tumor immunotherapies is currently in its preliminary stages. Although senescence has the greatest impact on ICB therapies, mechanistic investigations, and drug development for APOE and sirt1-7 (Sirtuins family) targets may be the key to combining senescence therapies with immunotherapies in the treatment of tumors.
    Keywords:  aging; bibliometrics; cancer; immunotherapy; senescence; visualization
    DOI:  https://doi.org/10.3389/fimmu.2025.1566227
  43. Int J Environ Res Public Health. 2025 Mar 31. pii: 531. [Epub ahead of print]22(4):
    Bibliometric Analysis of Corporate Social Responsibility and Its Impact on Community Health.
    Mauricio Guillen-Godoy, Dennis Peralta-Gamboa, Edy Guillen-Godoy.
      This study presents a bibliometric analysis of the intersection between Corporate Social Responsibility (CSR) and community health, aiming to identify research trends, key contributors, and thematic developments in the field. Using data from Scopus, this study maps the evolution of CSR literature with a focus on public health and sustainability. The findings indicate a marked increase in publications over the past decade, with significant contributions from institutions in the United States, the United Kingdom, and China. Key themes identified include workplace health promotion, ethical concerns in corporate practices, and the role of CSR in mitigating public health risks, particularly during global crises such as the COVID-19 pandemic. This study highlights gaps in the literature and suggests directions for future research, including the need for interdisciplinary approaches and policy-driven CSR strategies. The results provide a valuable reference for academics and policymakers seeking to align corporate responsibility efforts with global health objectives.
    Keywords:  bibliometric analysis; community health; corporate reputation; corporate social responsibility
    DOI:  https://doi.org/10.3390/ijerph22040531
  44. PCN Rep. 2025 Jun;4(2): e70101
    Mapping the landscape of mental health research through Google Trends: Bibliometric and thematic insights.
    Abhishek Ghosh, Blessy B George, Pragyapti Malav, Shinjini Choudhury, Sonu Goel.
       Aim: The rise of Internet usage has introduced innovative methods for public health research, particularly using Google Trends to understand mental health issues. This study aims to conduct a comprehensive bibliometric and content analysis of research utilizing Google Trends for mental health.
    Methods: We conducted a literature search on Scopus focusing on peer-reviewed articles from January 2010 to May 2024. Bibliometric analysis included descriptive statistics, bibliographic coupling, keyword co-occurrence, and coauthorship networks. Qualitative content analysis identified themes in the study objectives.
    Results: The bibliometric analysis revealed an increase in publications post-pandemic. The bibliographic coupling analysis identified the Journal of Medical Internet Research as central, with significant connections to journals like JMIR Public Health and Surveillance and BMC Public Health. Keyword co-occurrence highlighted themes such as "mental health," "COVID-19," "anxiety," and "social media." Author co-citation and coauthorship analyses showed strong closely linked collaborations, with a few central authors leading the research. Coauthor country analysis revealed limited international collaborations, particularly involving the United States and the United Kingdom. Content analysis identified six major themes: economic and social impacts, mental health during public health emergencies, online behavior, specific conditions and treatments, public health policies, and psychological and social impacts.
    Conclusion: This study underscores the importance of Google Trends in mental health research, revealing key trends and thematic focuses. The findings contribute to understanding the current research landscape and offer a foundation for future studies leveraging digital tools for mental health insights.
    Keywords:  Google Trends; bibliometric analysis; content analysis; mental health
    DOI:  https://doi.org/10.1002/pcn5.70101
  45. J Infect Public Health. 2025 Apr 10. pii: S1876-0341(25)00118-2. [Epub ahead of print]18(7): 102769
    Comparative bibliometric analysis of highly cited monkeypox research in general and specialized infectious disease journals: Dissecting trends, collaborations, and impact.
    Rui-Xuan Li, Zhi-Xin Li, Yu-Yue Shen, Jia-Jie Guo, Yue Liu, Jia-Yu Cai, Bin-Bin Xiang, Xin-Rong Ye, Xu-Guang Guo.
      This study employs bibliometric methods to analyze global publication trends in monkeypox (MPX) research from 2022 to 2024. Using the Web of Science Core Collection database, we identified the top 100 cited articles from all journals and infectious disease specialty journals. The United States and the United Kingdom were the most productive countries, with significant contributions from African nations like Nigeria. Key institutions included the Centers for Disease Control and Prevention (CDC) and the University of London. Research focused on virus transmission, clinical manifestations, and treatments, especially vaccines and antiviral strategies after MPX was declared a Public Health Emergency of International Concern (PHEIC). Our findings offer micro-level insights into biological mechanisms and targeted therapies, as well as macro-level perspectives on international collaboration and policy impact. These results are essential for guiding future diagnostic, therapeutic, and preventive strategies.
    Keywords:  Bibliometrics; Collaborative research; Global health; Monkeypox; Scientific publications
    DOI:  https://doi.org/10.1016/j.jiph.2025.102769
  46. Pharmaceutics. 2025 Apr 01. pii: 451. [Epub ahead of print]17(4):
    A Bibliometric Analysis and Systematic Review of Research Advances in In Situ Gel Drug Delivery Systems from 2003 to 2023.
    Huanyu Zhou, Mingqing Yuan, Tao Zhang.
      Objective: We aimed analyze research trends in in situ gel drug delivery systems. Methods: Studies from 2003 to 2023 were systematically obtained from the Web of Science database and analyzed using VOSviewer software to evaluate publication trends, citation patterns, and collaborative networks. Results: A total of 990 articles were reviewed. There has been a significant increase in publications since 2019, with the highest number of publications occurring in 2023. China was the leading country in terms of publication output. Cairo University and King Abdulaziz University were identified as the top contributing institutions. Key researchers included Zhao, Xia, Hosny, and Kim. The research primarily focused on developing new formulations, optimizing materials (e.g., biocompatible and biodegradable materials), and exploring clinical applications such as nasal-brain delivery for Alzheimer's treatment. Conclusions: In situ gel systems have gained widespread use in clinical practice due to their ability to provide prolonged drug release and enhance patient compliance. This area remains crucial for future research, particularly in formulation design and administration methods.
    Keywords:  VOSviewer; bibliometrics; drug delivery system; hydrogel; in situ gel; in situ gel formulation
    DOI:  https://doi.org/10.3390/pharmaceutics17040451
  47. Foods. 2025 Apr 14. pii: 1349. [Epub ahead of print]14(8):
    Global Status, Recent Trends, and Knowledge Mapping of Olive Bioactivity Research Through Bibliometric Analysis (2000-2024).
    Manuel Garrido-Romero, Marina Díez-Municio, F Javier Moreno.
      Over the past two decades, both academic and industrial interest in olive bioactive compounds has grown significantly due to their remarkable health benefits, such as antioxidant, anti-inflammatory, and cardioprotective properties. These compounds, found in both olive fruit and leaves, have become a central focus in the research on functional foods and nutraceuticals. A comprehensive bibliometric analysis of scientific publications from 2000 to 2024 highlights a notable increase in this field, with 2228 documents published in high-impact journals with an estimated annual growth rate of 0.2694 year-1, particularly in the last decade. This surge reflects the growing recognition of olive bioactive compounds' potential in promoting human health through nutritional and therapeutic interventions, and their role in the expanding nutraceutical industry. This growth is further reaffirmed by patent analysis, which shows a significant rise in industrial interest and patent filings related to olive bioactive compounds. The analysis also examined nearly 6000 keywords to identify the most influential research domains, pinpoint knowledge gaps, and reveal the most important bioactive compounds in olives and their potential in preventing various human diseases.
    Keywords:  Mediterranean diet; bioactive compounds; functional foods; nutraceuticals; oil; olive
    DOI:  https://doi.org/10.3390/foods14081349
  48. Nurse Educ Today. 2025 Apr 03. pii: S0260-6917(25)00173-X. [Epub ahead of print]152 106737
    Visual analysis of research status and development trends in the field of postgraduate nursing education.
    Tingting Ren, Tingrui Wang, Guoyan Wu, Qiaoxing Li, Yi Shu, Lei Shi, Li Yao, Hong Li, Junxin Chen.
       AIM: The purpose of this study was to systematically analyze the research status and development trends in the field of postgraduate education in nursing through visual analysis.
    METHODS: We conducted a comprehensive online search of English literature via citation index extensions in the Web of Science Core Collection Database. Chinese literature was searched online via the CNKI, Wanfang, VIP and China Medical Biobank Databases. The literature on postgraduate nursing education, including 8986 English studies and 3589 Chinese studies, was searched from 2004 to 2024. COOC, VOS Viewer and Cite Space software are used as research and analysis tools to discuss the research trends and hotspots in this field.
    RESULTS: The Chinese and English databases contained 8986 and 3764 relevant articles, respectively. The amount of English literature was increasing annually, whereas the amount of Chinese literature was growing steadily. With respect to nations, organizations, and writers, the U.S. had the greatest number of English-language publications. That said, there were few collaborative efforts between writers or institutions, and there was no cooperative team centered on a particular institution or author; rather, research institutions were independent and decentralized. The most popular works in Chinese literature were clinical research directions such as curriculum thinking and politics, innovative teaching reform mode, core competitiveness, and cross-professional education. The hot topics in English literature were resilience, academic practice partnership, empathic capacity and other mechanisms.
    CONCLUSION: The amount of international research was growing year by year, and the United States dominated the field, but a global network of collaborations had yet to be formed. The number of domestic research was growing steadily. There were differences in research hotspots at home and abroad. In the future, postgraduate nursing education needs to strengthen international cooperation, optimize curriculum Settings, promote teaching innovation, and pay attention to students' mental health, so as to improve education quality and students' comprehensive ability.
    DOI:  https://doi.org/10.1016/j.nedt.2025.106737
  49. J Pediatr Surg. 2025 Apr 24. pii: S0022-3468(25)00183-6. [Epub ahead of print] 162338
    Return of the Disruption Score: Fetal Surgery in the Spotlight (1975-2021).
    Cortnie R Vaughn, Xiao-Yue Han, Marijane White, Adan Z Becerra, Andrew Chon, Raphael C Sun.
       INTRODUCTION: Fetal surgery is a highly specialized multidisciplinary field which evolved from pediatric surgery and maternal-fetal medicine. The published works that define the field are found across the spectrum of subspeciality journals, making a comprehensive review of the literature difficult. The disruption score is a bibliometric tool which places each published work in the context of the existing literature with negative scores representing developmental works and positive scores representing disruptive works, which tend to be paradigm shifting. To our knowledge, this is the first study aiming to characterize developmental and disruptive papers in fetal surgery.
    METHODS: A set of literature searches were performed in PubMed/MEDLINE capturing articles on fetal conditions of neural tube defects (NTD), twin twin transfusion syndrome (TTTS), congenital diaphragmatic hernia (CDH), and congenital pulmonary airway malformation (CPAM) and their associated interventions. Each article was reviewed, and a disruption score (-1 to +1) was obtained. Disruption scores were available for articles published from 1975-2021. Articles were then categorized as either developmental (negative scores) or disruptive (positive score). Articles with the highest disruptive and developmental scores, along with the top cited, were identified.
    RESULTS: Within the field of fetal surgery, the top cited and top developmental fetal surgery papers occurred most frequently in 2010-2015, while the top disruptive fetal surgery papers most frequently occurred after 2020. NTD and CPAM had a higher proportion of developmental papers, while CDH and TTTS demonstrated more disruptive works. While there was overlap among top cited and top developmental works, disruptive analysis provided depth to characterization of the literature.
    CONCLUSIONS: This is the first attempt to characterize impactful works of research within fetal surgery using disruption score. This bibliometric analysis, compared to traditional methods, may highlight key articles facilitating advancement within fetal surgery.
    EVIDENCE: V.
    Keywords:  Fetal surgery; bibliometrics; disruption score
    DOI:  https://doi.org/10.1016/j.jpedsurg.2025.162338
  50. Nutrients. 2025 Mar 18. pii: 1064. [Epub ahead of print]17(6):
    Mapping Research Trends on Intestinal Permeability in Irritable Bowel Syndrome with a Focus on Nutrition: A Bibliometric Analysis.
    Domenica Mallardi, Fatima Maqoud, Davide Guido, Michelangelo Aloisio, Michele Linsalata, Francesco Russo.
      Irritable Bowel Syndrome (IBS) is a complex gastrointestinal disorder characterized by chronic abdominal pain and altered bowel habits, often linked to disruptions in intestinal barrier function. Increased intestinal permeability plays a key role in IBS pathogenesis, affecting immune responses, gut microbiota, and inflammation. This study conducts a bibliometric analysis to explore global research trends on intestinal permeability in IBS, focusing on key contributors, collaboration networks, and thematic shifts, particularly the interplay between the intestinal barrier, gut microbiota, and dietary components. A total of 411 articles were retrieved from Scopus, with 232 studies analyzed using Bibliometrix in R. To optimize screening, ASReview, a machine learning tool, was employed, utilizing the Naïve Bayes algorithm combined with Term Frequency-Inverse Document Frequency (TF-IDF) for adaptive ranking of articles by relevance. This approach significantly improved screening step efficacy. The analysis highlights growing research interest, with China and the USA as leading contributors. Key themes include the role of gut microbiota in modulating permeability, the impact of dietary components (fiber, probiotics, bioactive compounds) on tight junction integrity, and the exploration of therapeutic agents. Emerging studies suggest integrating gut barrier modulation with nutritional and microbiome-targeted strategies for IBS management. This study provides a comprehensive overview of research on intestinal permeability in IBS, mapping its evolution and identifying major trends. By highlighting key contributors and thematic areas, it offers insights to guide future investigations into the interplay between gut permeability, diet, and microbiota, advancing understanding of IBS pathophysiology and management.
    Keywords:  ASReview; bibliometric analysis; gut microbiota; intestinal permeability; irritable bowel syndrome; machine learning; nutrition; probiotics
    DOI:  https://doi.org/10.3390/nu17061064
  51. PLoS One. 2025 ;20(4): e0322012
    Reputation shortcoming in academic publishing.
    Rémi Neveu, André Neveu.
      Editors of scientific journals make central decisions in the publication process. Information peripheral to the content of a manuscript such as the editor's professional circle and authors' publishing record may influence these decisions. This constitutes reputation whose role in the publication process remains poorly investigated. Analyzing three decades of publications of 33 Nature journals in physical and life sciences, we show that reputation is tied with publications at the level of editors. The establishment of a non-financial conflict of interest policy and the journals' impact factor were associated with changes in the number of publications of editors' former co-authors and authors with a publishing record in Nature journals. We suggest changes at the author and journal levels to mitigate the role of reputation in the publication process.
    DOI:  https://doi.org/10.1371/journal.pone.0322012
  52. Front Med (Lausanne). 2025 ;12 1545678
    A systematic review of hypervirulent Klebsiella pneumoniae research: bibliometric and topic modeling perspectives.
    Tian Tian, Hui Han, Zhi-Hui Guan, Ke Zhang, Xinghe Huang, Wenyue Wang, Xuan Zhang, Fei Zhang, Leijia Wei, Xin Zhang, Jia-He Wang.
       Background/objective: Hypervirulent Klebsiella pneumoniae (hvKP) is an emerging global health threat, exhibiting increased virulence and multidrug resistance compared to classic K. pneumoniae. Understanding the research landscape surrounding hvKP is crucial for developing effective control strategies. This study aimed to comprehensively analyze the global research trends in hvKP from 2013 to 2024 using bibliometric and topic modeling techniques.
    Methods: Data from 1,014 articles on hvKP, retrieved from the Web of Science Core Collection, were analyzed using Bibliometrix, CiteSpace, and VOSviewer to assess publication trends, collaborations, geographical distribution, and keyword co-occurrence. Latent Dirichlet Allocation (LDA) topic modeling was employed to identify key research themes.
    Results: The analysis revealed a steadily increasing volume of hvKP research, with China and the United States as major contributors. Four primary research themes emerged: high virulence phenotypes and mechanisms; drug resistance and treatment strategies; genetic and molecular mechanisms; and epidemiological and transmission characteristics. Research hotspots included virulence mechanisms, drug resistance, genomic detection approaches, and epidemiological features.
    Conclusion: This bibliometric analysis provides a comprehensive overview of hvKP research, highlighting key trends and research gaps. The identified research hotspots inform future research directions and contribute to the development of effective strategies for combating hvKP infections. The increasing research volume underscores the urgent need for continued investigation into this significant public health threat.
    Keywords:  Klebsiella pneumoniae; antimicrobial resistance; bibliometrics; epidemiological characteristics; hypervirulence; hypervirulent Klebsiella pneumoniae; topic modeling
    DOI:  https://doi.org/10.3389/fmed.2025.1545678
  53. J Surg Educ. 2025 Apr 28. pii: S1931-7204(25)00101-1. [Epub ahead of print]82(6): 103521
    Resident-led Research Initiative Drives Collaboration and Productivity: A Bibliometric Network-Based Analysis.
    Colleen P Nofi, Molly Kobritz, Bailey K Roberts, Maya Vasser, Leanna Stager, Jaclyn Morales, Vihas Patel.
       OBJECTIVE: Collaborative clinical research among trainees can accelerate new discoveries, improve nontechnical skills, and foster career growth. However, various obstacles exist which make research efforts during surgical training challenging. The purpose of this study was to evaluate whether a resident-led digital research infrastructure was associated with increased academic productivity among individuals and collaboration in scholarship during surgical training.
    DESIGN: A multimodal resident-led initiative, Surgery Residents' Research Forum (SuRRF) was implemented in 2019. Databases were queried for publications for surgical residents and fellows from 2015 to 2023. Bibliometric network maps were created to evaluate scholarly activity and collaboration before and after SuRRF implementation. Networks consisted of clusters (representing set of related research items), linkages (representing co-authored items), and link strength (representing increased frequency of co-authorship).
    SETTING: Residency and fellowship programs from teaching hospitals of an integrated health system in New York.
    PARTICIPANTS: General surgery and surgical subspecialty residents and fellows.
    RESULTS: A mean of 77 trainees were included each AY. Trainee participation in research increased from 26.1% in 2015 to 2016 to 62.5% in 2022 to 2023. The number of research items increased from 30 in 2015 to 2016 to 135 in 2022 to 2023. Bibliometric network analysis revealed an increase in research clusters, number of linkages, and link strength from 2015 to 2016 (10, 11, and 13 respectively) to 2022 to 2023 (25, 80, and 126, respectively). Pre-SuRRF to post-SuRRF analysis revealed a significant increase in the number of research items (40.25-109.5, p = 0.002), number of research clusters (11.75-23.25, p < 0.001), number of links (9.5-50.5, p = 0.027), and link strength (13.0-75.5, p = 0.029).
    CONCLUSION: The resident research initiative, SuRRF, was associated with increased collaboration and academic productivity. Expanding similar programs nationally could enhance clinical research feasibility and foster a culture of collaboration and academic growth for surgical residents and fellows.
    Keywords:  collaboration; education; research; research forum; surgery residency
    DOI:  https://doi.org/10.1016/j.jsurg.2025.103521
  54. Perioper Med (Lond). 2025 Apr 30. 14(1): 50
    Global research trends in perioperative care for diabetic patients: a bibliometric and visualized study.
    Jiangru Kang, Xin Chai, Tao Jia, Huiru Hu, Rong Fu, Huang Nie.
      Perioperative management in diabetic patients is important since their postoperative mortality and morbidity are higher than that of non-diabetic patients, which will exacerbate the burden on public health. We selected relevant publications from the WoSCC-SCIE between 2007 and 2024, utilizing VOSviewer and CiteSpace to analyze the collected information and generate knowledge maps. A total of 3167 articles from 792 journals and 83 countries/regions were included for analysis. Overall, there has been a continuous increase in publication volume. From the result of academic collaboration between different countries/regions and institutions, the USA occupies a central position in research strength. A total of 18,101 authors participated in research on "perioperative management in diabetic patients" with Dr. Guillermo E. Umpierrez from Emory University School of Medicine being the most productive author. We conclude that perioperative adverse clinical outcomes in diabetic patients and perioperative blood glucose management have consistently been research hotspots in this field. Additionally, continuous glucose monitoring and insulin administration under computer guidance, as well as the use of merging medications are likely to be frontier directions for future research. Research on perioperative care for diabetic patients has been further deepened worldwide, which will be crucial in further improving perioperative care for diabetic patients and enhancing postoperative recovery.
    Keywords:  Bibliometric analysis; Diabetes; Perioperative care; Visualized analysis
    DOI:  https://doi.org/10.1186/s13741-025-00532-w
  55. Healthcare (Basel). 2025 Apr 13. pii: 891. [Epub ahead of print]13(8):
    What Has Been Studied About Attitudes and Social Stigma Towards HIV/AIDS? A Global Bibliometric Study with Correlations on Global Health HIV-Related Indicators.
    Yelson Alejandro Picón-Jaimes, Ivan David Lozada-Martinez, Mar Rosàs Tosas, Juan Tiraboschi, Ornella Fiorillo-Moreno, Valmore Bermúdez.
      Introduction: This study aimed to assess, through health metrics and bibliometric analysis, the global research on attitudes and social stigma of people living with HIV/AIDS and to identify research findings, gaps, and future directions. Methods: A cross-sectional bibliometric study was conducted through a structured search in different databases. Fifteen thousand four hundred and ninety-six documents were found between 1981 and 2024. Results: 83.5% were original articles, and international co-authorship was 30.66%. Since 2000, there has been an increase in research on HIV/AIDS attitudes and social stigma. The United States is the most prolific country worldwide (n = 7837 publications; 50.5%), with the highest number of prolific institutions (n = 4/5), as well as the greatest influence and relevance in research (h-index 170). The most studied topics worldwide are social support and social psychology concerning homosexuality, middle age, and youth in people living with HIV/AIDS. There was no significant correlation between the volume of publications, countries' income levels, and the most prolific geographic regions with adult HIV prevalence, overall HIV incidence and prevalence, or antiretroviral therapy coverage in people living with HIV (p > 0.05 for all cases). Conclusions: Over the past two decades, research has shifted from human rights, legal rights, and ethics to attitudes toward healthcare, with the recent interest in pre-exposure prophylaxis, gender minorities, and intersectional stigma. The absence of strong correlations between publications volume and global health HIV-related indicators underscores the necessity of translating evidence into actionable strategies to reduce stigma and improve health outcomes.
    Keywords:  HIV; acquired immunodeficiency syndrome; attitudes; global health; health knowledge; microaggression; social stigma
    DOI:  https://doi.org/10.3390/healthcare13080891
  56. New Microbiol. 2025 May;48(1): 46-59
    Knowledge Mapping of International Microbiota Research: Analyzing Thirty-Year Citation Classics and Exploring Future Expectations.
    Xiang Li, Kunkai Su, Yueyue He, Shimiao Shao, Lei Lan, Qiong Zhang.
      Microbiota research has rapidly emerged as a pivotal field, with over 250,000 publications and more than ten million citations recorded in the Web of Science Core Collection database by 2024. There were 1682 original microbiota citation classics (each receiving 400 citations or more) identified over the past three decades, totaling 1,559,594 citations and averaging 927 citations per paper. Collaborative efforts in the production of these citation classics involved 87 out of 89 participating countries and 2107 out of 2142 institutions. The USA, various European countries, and China emerged as the leading contributors to this burgeoning research area. Jeffrey I. Gordon, Rob Knight, and Curtis Huttenhower were the prominent figures in microbiota research. Author keywords were analyzed, which revealed a notable shift in research focus from environmental microorganisms to human gut microbiota. Advances such as high-throughput 16S rRNA sequencing and metagenomics expanded the scope of investigations into host-microbiota interactions. Current research interests encompass exploring mechanisms underlying gut-X-axis conditions, including inflammatory bowel disease, obesity, diabetes, colorectal cancer, liver diseases, and neurological disorders. Moreover, environmental exposures have been evidenced to alter gut microbiota and metabolites, contributing a novel research direction. Future research direction is also anticipated to delve further into biosynthetic gene engineering technologies aimed at microbial interventions, including probiotics and fecal microbiota transplantation. This study outlines the evolving landscape of microbiota research and provides valuable insights to inform future investigations within the field.
    Keywords:  Microbiota; citation classics; collaboration research; technology advancements
  57. Arthrosc Sports Med Rehabil. 2025 Apr;7(2): 101076
    Persistent Gender Disparity in Authorship of Arthroscopic Surgery Research.
    Uma Balachandran, Auston R Locke, Niklas H Koehne, Charu Jain, Camila Vicioso, Jiwoo Park, Katrina S Nietsch, Alexis C Colvin.
       Purpose: To examine how the gender of the first and last authors of annual meeting abstracts and journal articles from a related source have changed between 2012 and 2022.
    Methods: All abstracts and original research articles published from 2012 to 2022 were extracted from the websites of The Arthroscopy Association of North America and Arthroscopy: The Journal of Arthroscopic and Related Surgery, respectively. The full names of first and last authors were analyzed with the validated Genderize algorithm. Analyses were performed to evaluate authorship of abstracts and articles.
    Results: Of 850 abstracts, 845 (99.4%) had an identifiable first-author gender and 843 (99.2%) had an identifiable last-author gender. The proportion of female first authors increased from 9.2% in 2012 to 15.2% in 2022, whereas the proportion of female last authors decreased from 13.5% in 2012 to 12.3% in 2022. Of 4,811 articles, 4,744 (98.6%) had an identifiable first author gender and 4,767 (99.1%) had an identifiable last author gender. The proportion of female first authors increased from 10.4% in 2012 to 16.8% in 2022, whereas the proportion of female last authors decreased from 19.0% in 2012 to 9.1% in 2022. For both abstracts and articles, the gender of the last author was not significantly associated with the presence of a female first author.
    Conclusions: Between 2021 and 2022, there was a significant increase in the proportion of female first authors of both abstracts and articles examined in this study. However, a similar increase was not seen among last authors.
    Clinical Relevance: It is important to examine gender representation among authors who publish arthroscopic research to understand how a greater balance may be achieved.
    DOI:  https://doi.org/10.1016/j.asmr.2025.101076
  58. Biology (Basel). 2025 Apr 02. pii: 365. [Epub ahead of print]14(4):
    Current Progress and Future Trends in Carbon Sources and Sinks in Farmland Ecosystems: A Bibliometric Analysis (2002-2023).
    Yugong Pang, Menghao Zhang, Hesen Zhong, Tibihenda Cevin, Chuanzhun Sun, Shoutao Zhang, Xinyu Li, Jun Dai, Chengshuai Liu, Chi Zhang.
      Farmland ecosystems, as the most active carbon pool, are integral to global climate change and carbon cycling. Therefore, systematically studying the roles of carbon sources and sinks in farmland ecosystems is essential to deepening our understanding of the carbon cycle and meeting the goals of "peak carbon emissions" and "carbon neutrality" in agriculture. Using the Web of Science database, this study reviewed 1411 articles (2002-2023) via bibliometric analysis to identify key research themes, trends, future priorities and address suggestions for future directions in farmland ecosystem carbon sources and sinks. The main results include the following: (1) Over the past 22 years, global research in this field has shown a consistent growth trend, with remarkably rapid expansion in the past three years. China, the United States, and Germany are the most influential countries. As the research scope has expanded, the field has evolved into an interdisciplinary domain. (2) The diversity of this research area has become enriched, and the research content is becoming more refined and systematic. The main research topics focus on carbon sequestration, soil organic carbon (SOC), farmland management, greenhouse gas (GHG) emissions, carbon stocks, ecosystem services, land use changes, climate change, and spatiotemporal heterogeneity. (3) Current research hotspots primarily focus on studying soil microbial carbon sequestration mechanisms, the application of remote sensing technologies, and reducing GHG emissions to achieve "carbon neutrality". While existing studies have systematically elucidated carbon sequestration mechanisms mediated by soil aggregates, microorganisms, and minerals, critical knowledge gaps persist. Regional disparities in the relative contributions of these mechanisms remain unresolved, compounded by methodological inconsistencies in carbon assessment that introduce substantial uncertainties. Although farmland management practices are identified as pivotal drivers of carbon flux variation, the interactive effects of anthropogenic interventions and natural factors on ecosystem-scale carbon balance require further mechanistic exploration. This review provides a comprehensive reference for further study on carbon sources and sinks of farmland ecosystems and devising effective emission reduction strategies.
    Keywords:  bibliometric analysis; carbon sequestration; carbon sink; carbon sources; farmland ecosystem; soil organic carbon (SOC)
    DOI:  https://doi.org/10.3390/biology14040365
  59. Microorganisms. 2025 Mar 25. pii: 740. [Epub ahead of print]13(4):
    Advances, Challenges, and Perspectives in Glomalin-Related Soil Protein Research.
    Qiumei Ling, Hanqing Wu, Lei Xie, Yuan Zhao, Qibo Huang, Qian Zhang, Ji Liu, Peilei Hu, Tiangang Tang, Jun Xiao, Hu Du, Jie Zhao, Wei Zhang, Hongsong Chen, Kelin Wang.
      Glomalin-related soil protein (GRSP), a glycoprotein primarily exuded by arbuscular mycorrhizal fungi (AMF), exerts key roles in ecological processes in terrestrial ecosystems. Nevertheless, the intricate nature of GRSP, coupled with constraints in its extraction and analytical methodologies, impedes a comprehensive understanding of its compositional attributes and ecological functions. Moreover, the scope of current GRSP research has undergone significant expansion, necessitating a comprehensive synthesis in this field. Here, we employed bibliometric analysis to systematically assess research trends and hotspots in the research field of GRSP based on 840 relevant articles indexed in the Web of Science Core Collection database. Among them, key parameters evaluated encompass publications' quantity, highly cited articles, high-frequency keywords, and historical direct citations. These analyses illuminated the state-of-the-art of GRSP research, delineated emergent trends, and provided future perspectives. Current investigations into GRSP predominantly focus on three major topics: (i) GRSP's nature, origin, and quantification methodologies; (ii) GRSP's key influencing factors including agricultural management practices, climate and land use change; and (iii) GRSP's ecological functions enhancing soil aggregate stability, C sequestration, and contamination remediation. Our findings can serve as a scholarly resource for advancing inquiries into the ecological functionalities of GRSP and its prospective applications in sustainable soil management and ecological restoration.
    Keywords:  GRSP; bibliometric analysis; carbon cycling; extracellular polymeric substance; research hotspots; soil organic carbon
    DOI:  https://doi.org/10.3390/microorganisms13040740
  60. Am Psychol. 2025 Apr 28.
    Publication trends for qualitative inquiry in American Psychological Association and Association for Psychological Science journals.
    Tamara Stecyk, Dennis C Wendt, Sophie Blackmore.
      Framed against the long-standing dominance of quantitative methods in psychological science, this study examined contemporary publishing patterns for qualitative inquiry in American Psychological Association (APA) and Association for Psychological Science (APS) journals. We examined 19,012 publications across 95 APA and APS journals across four time points (2005, 2012, 2019, and 2022). The percentage of qualitative articles was determined using the methodology field value within APA PsycInfo, a process that we validated through a batch test. We also conducted a content analysis of journal mission statements and submission guidelines, and we made comparisons in light of journal impact factors. Our findings show a nearly threefold increase in qualitative publications accelerating over time from 2005 to 2022, albeit with wide variations depending on the type of journal. Qualitative-friendly journals were more likely to be published by APA, be specialty journals, be dedicated to diverse populations, and have lower impact factors. Conversely, qualitative research was less likely to be published in APS journals, core psychology journals, journals focused on general populations, and journals with higher impact factors (with some notable exceptions). We discuss these findings in terms of implications for the advancement of psychological science, including the discipline's need for development in qualitative training and expertise, its commitments to antiracism and anticolonialism, its fragmentation, and its equity in publishing. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
    DOI:  https://doi.org/10.1037/amp0001526
  61. J Virus Erad. 2025 Mar;11(1): 100582
    Global trends in Marburg virus disease: Another potential threat to global health in the making?
    Tauseef Ahmad.
      Image 1.
    Keywords:  Bibliometric; Marburg virus; Network collaboration; Scopus; Thematic evolution; Web of Science Core Collection
    DOI:  https://doi.org/10.1016/j.jve.2025.100582
  62. Med Sci Monit. 2025 May 01. 31 e948365
    Defining Effect Size Standards in Temporomandibular Joint and Masticatory Muscle Research.
    Grzegorz Zieliński, Piotr Gawda.
      BACKGROUND The interpretation of effect sizes is critical in scientific research, particularly in health and medicine, as it helps assess the strength and significance of experimental results. However, standardized guidelines for interpreting effect sizes in temporomandibular joint (TMJ) and masticatory muscle research are lacking. This study aims to propose new guidelines for interpreting group differences in research on the TMJ and masticatory muscles. MATERIAL AND METHODS The study is a bibliometric analysis based on meta-analyses published in the top 20 ranked dental journals. The study included 16 meta-analyses, comprising a total of 456 studies. In these records, 26,662 participants were analyzed (12,102 in the first group and 14,560 in the second group). Effect size metrics, including Cohen's d, and Hedges' g, were analyzed. The primary outcomes were the 25th, 50th, and 75th percentiles of effect size measures for TMJ and masticatory muscle studies. Data were stratified by effect size metrics (Cohen's d, and Hedges' g). Statistical analyses were conducted using R programming to compute the percentiles of effect sizes. RESULTS For group differences, the values of Hedges' g corresponding to the 25th, 50th, and 75th percentiles were 0.11, 0.34, and 0.74, respectively. CONCLUSIONS Researchers studying the TMJ and masticatory muscles are encouraged to adopt the following thresholds: 0.1 for small effects, 0.3 for medium effects, and 0.7 for large effects, for both Cohen's d and Hedges' g. These guidelines provide a standardized approach to effect size interpretation, enhancing the reliability and relevance of findings in TMJ research.
    DOI:  https://doi.org/10.12659/MSM.948365
  63. Biochim Biophys Acta Mol Basis Dis. 2025 Apr 29. pii: S0925-4439(25)00226-1. [Epub ahead of print] 167878
    Scientometric analysis of evolution in sex-specific MSC therapy for cardiovascular diseases.
    Elika Verma, Mehak Gupta, Riley Sierhuis, Sanjiv Dhingra.
       BACKGROUND: Mesenchymal stem cell (MSC) therapy for cardiovascular diseases has shown promise; however, sex-specific differences remain understudied. This scientometric analysis provides the first comprehensive overview of sex-specific differences in mesenchymal stem cell (MSC) therapy for cardiovascular diseases, spanning from 1947 to 2024.
    METHODS: We analyzed 61,029 publications using advanced bibliometric tools to identify research hotspots, publication trends, and collaborative networks.
    RESULTS: A significant shift in research focus has been observed in the field of mesenchymal stem cell (MSC) therapy for cardiovascular diseases, transitioning from broad cardiovascular concepts in the 20th century to specialized sex-specific considerations in the 21st century. Furthermore, in the 21st-century research landscape, the formation of two distinct clusters for "male" and "female" in VOSviewer-generated network visualizations is highly important, emphasizing the growing recognition of sex-specific differences in MSC therapy responses and outcomes. This shift was accompanied by a marked increase in terminology related to sex-specific differences, with keywords like "genetic association" and "body mass index" forming distinct clusters in recent years.
    CONCLUSIONS: This analysis underscores the critical need for sex-specific considerations in MSC therapy for cardiovascular disease. The emergence of distinct male and female clusters in research networks emphasizes the importance of tailoring approaches based on sex differences. Key areas identified for future investigation include the role of epigenetics in mediating sex-specific effects and the potential of sex-matched MSC-derived exosomes. These findings pave the way for more effective and personalized approaches in cardiovascular regenerative medicine, potentially leading to improved outcomes through sex-specific therapeutic strategies.
    Keywords:  Cardiovascular disease; Mesenchymal stem cells; Scientometric analysis; Sex
    DOI:  https://doi.org/10.1016/j.bbadis.2025.167878
  64. Environ Health Insights. 2025 ;19 11786302251327290
    Global Research Hotspots and Progress on Acrylamide: Visualization Analysis.
    Shaher Zyoud, Sa'ed H Zyoud.
      Acrylamide is a contaminant prevalent in many commonly consumed foods, contributing to unavoidable human exposure. It is recognized as likely to be carcinogenic to humans as well, provoking global concerns. Numerous studies have investigated the impacts of acrylamide formation on food and drink, nutrition, and health. The intent of this analysis is to quantify global acrylamide research, evaluate recent developments, and recognize emerging trends, along with assessing research dynamics as an indicator of innovation among the scientific community. The Scopus database was used to perform an in-depth investigation of scientific publications on acrylamide from 1949 to 2023. Exploring prominent topics and the knowledge network related to the topic was conducted via VOSviewer version 1.6.20. Additionally, using SciMAT software, intellectual analysis was conducted to identify both driving and emerging themes in acrylamide-related research. A total of 11 880 publications on acrylamide were identified, with 10 720 (90.24%) being original articles. The leading contributors in terms of publication output were China (n = 2452; 20.64%), followed by the USA (n = 1564; 13.16%), and India (n = 952; 8.01%). The predominant themes were associated with (a) the functionalization of acrylamide polymers and (b) the formation and mitigation of acrylamide in food and drinks. Driving themes that will continue to shape the future of acrylamide research involve unraveling the synthesis of acrylamide; deploying acrylamide in nanocomposites to increase contaminant removal; investigating the genotoxicity of acrylamide, as well as its carcinogenic, reproductive, and neurotoxic effects; and researching the adsorption characteristics of acrylamide in aqueous solutions. In particular, an increased focus has been placed on understanding the formation and mitigation of acrylamide in recent years, signifying increased attention and alignment with the latest scientific advancements in this field. The creation of research plans in this way is significant, particularly in shaping future health policies.
    Keywords:  acrylamide; carcinogenetic; dietary habits; health risks; nanocomposites; visualization
    DOI:  https://doi.org/10.1177/11786302251327290
  65. Arthrosc Sports Med Rehabil. 2025 Apr;7(2): 101042
    Academic Productivity at Orthopaedic Surgery Sports Medicine Fellowship Programs in the United States Has a Weak Positive Correlation With Nonresearch Lifetime Industry Earnings.
    Benjamin Miltenberg, William L Johns, Anthony N Baumann, Faheem Pottayil, Bradley Richey, Albert T Anastasio, Kempland C Walley, Christopher C Dodson, Sommer Hammoud.
       Purpose: To characterize the relationship between academic productivity, as defined by the h-index, and industry payments for fellowship-trained sports medicine surgeons in faculty positions at sports medicine fellowships.
    Methods: The American Orthopaedic Society for Sports Medicine fellowship directory was used to create a comprehensive list of all fellowship programs nationwide. Fellowship websites were then reviewed to generate a list of the teaching faculty associated with each program. Total nonresearch lifetime earnings were obtained from the Centers for Medicare & Medicaid Services website. Academic productivity of each fellowship faculty was assessed via the h-index. Frequency counts and other descriptive statistic measures were used to describe the data for this study. Correlation was performed for continuous data using Spearman's ρ.
    Results: Ninety orthopaedic surgery sports medicine fellowships were identified with a combined total of 574 orthopaedic surgery sports medicine fellowship faculty. There was a weak positive correlation between individual physician h-index and individual physician lifetime earnings at orthopaedic surgery sports medicine fellowships (P < .001; Spearman's ρ = 0.329). There was a statistically significant difference between individual faculty h-index by quartile and individual faculty lifetime earnings (test statistic: 47.3; P < .001). There was no significant regional difference in payments, but there is remarkable heterogeneity in the distribution of payments to individual physicians, with the top 10% of physicians receiving over 80% of industry dollars.
    Conclusions: There is a positive correlation between academic productivity and industry payments at both the individual and institutional levels in orthopaedic sports medicine departments, although this relationship was greater at the fellowship level. Furthermore, the majority of nonresearch industry funding goes to a minority of physicians.
    Clinical Relevance: Evaluating the impact that nonresearch industry payments have on a sports medicine orthopaedic surgeon's research productivity can offer valuable insights into the relationship between industry compensation and scholarly output in this field.
    DOI:  https://doi.org/10.1016/j.asmr.2024.101042
  66. Facial Plast Surg. 2025 Apr 25.
    H-index or Hype Index? Are High H-Index Surgeons the Real Influencers on Social Media?
    Kiran Abraham-Aggarwal, Andrew B Yang, Daniel J Spertus, John L Frodel.
       INTRODUCTION: Social media platforms, particularly TikTok and Instagram Reels, have transformed professional visibility in medicine. Facial plastic surgeons (FPS) leverage these platforms for public education and patient outreach. However, the relationship between social media popularity and scholarly impact remains unclear. Objectives & Hypotheses: This study examines whether an otolaryngologist's social media presence correlates with their H-index, a measure of academic credibility. We hypothesize that higher H-index scores predict greater social media engagement on Instagram and TikTok.
    STUDY DESIGN: Cross-sectional study.
    METHODS: We extracted HypeAuditor data for TikTok and Instagram engagement metrics among users with otolaryngology content with ≥25,000 followers. H-index was retrieved from Scopus, Web of Science, and Google Scholar. Correlation analyses were performed.
    RESULTS: Instagram H-index correlated positively with follower count and quality audience, while TikTok showed no significant association.
    CONCLUSIONS: Academic credibility influences Instagram engagement but not TikTok, highlighting platform-specific differences in professional influence.
    DOI:  https://doi.org/10.1055/a-2593-9968
  67. Ann Plast Surg. 2025 May 01. 94(5S Suppl 3): S465-S468
    Academic Influence and Industry Funding in Acellular Dermal Matrix Research: A Co-authorship Network Analysis.
    McKay D Reese, Yash A Mehta, Robert Craig Clark, Milan M Hirpara, Michael R Haupt, Chris M Reid.
       BACKGROUND: Previous research has demonstrated correlations between quantity of acellular dermal matrix (ADM) studies published and industry payments received. The present study extends this work by employing a co-authorship network analysis to quantitatively identify a broader cohort of influential investigators in the field of ADM and analyze their financial relationships with industry.
    METHODS: Studies from 11 plastic surgery journals focusing on ADM were retrieved from PubMed. Author names were extracted, cleaned, and placed into an adjacency matrix to generate a co-authorship network. Degree centrality, a representation of influence within the network, was then quantified for each author. Total industry payments received from ADM-producing companies were calculated for authors with exceptional centrality, defined as >11 (95th percentile; n = 99), using the Open Payments database. Spearman's rank correlation and simple linear regression were used to analyze the relationship between centrality and payments received.
    RESULTS: A total of 1651 authors (nodes) from 535 studies were incorporated into the network, with 9360 co-authorships (ties) between them. Ninety-nine authors attained a centrality >11. Of the 57 US-based clinicians within this cohort of 99, 49 (86%) received at least one payment from an ADM-producing company. The average total payment received for this cohort was $98,756 (SD, $262,405). The grand total for all authors was $4,839,086. Spearman correlation revealed a significant positive correlation between centrality and industry payments (ρ = 0.31; 95% CI, 0.027-0.54; P < 0.05). Simple linear regression demonstrated an estimated 18% increase in total pay per additional unit of centrality (95% CI, 5%-30%; P = 0.007).
    CONCLUSIONS: This study examines academic influence in the realm of ADM research via a co-authorship network analysis and demonstrates a high prevalence of funding among influential authors as well as a significant relationship between centrality and payments received. These findings underscore the need for discussions concerning objectivity in clinical research, although it is uncertain whether academic influence is a target of industry or if industry support bolsters academic success.
    Keywords:  acellular dermal matrix; co-authorship network analysis; conflicts of interest; industry funding
    DOI:  https://doi.org/10.1097/SAP.0000000000004164
  68. Gait Posture. 2025 Apr 29. pii: S0966-6362(25)00186-9. [Epub ahead of print]121 1-8
    Movement analysis congress from yesterday to today: Text mining analysis.
    Orhan Ozturk, Mansur Alp Tocoglu.
       BACKGROUND: Despite the constant publication of motion analysis studies in the literature, the current focus of motion analysis laboratories is often showcased at conferences. Papers and abstracts presented at these events are a crucial source of information for scientists regarding the direction of research in the field. The most comprehensive congress in Europe for presenting current movement analysis studies for adults and children is the European Society for Movement Analysis in Adults and Children (ESMAC) RESEARCH QUESTION: How have motion analysis study trends changed in the last 15 years based on the papers presented at ESMAC congresses?
    METHODS: The titles of abstracts presented at the ESMAC congress between 2008 and 2023 were included in the study. Text mining was performed using the k-means algorithm in Python. Trend changes were analyzed in three groups of five years each.
    RESULTS: A total of 3038 paper titles presented at the ESMAC congress were included in the study. The most prominent term in the word cloud obtained from the paper titles was 'Cerebral Palsy.' The trending topics in each 5-year period were Cerebral Palsy, Gait Analysis, Balance, Foot, and Knee. The highest number of studies was presented in 2019 (n = 334), and the lowest in 2014 (n = 134).
    SIGNIFICANCE: While Cerebral Palsy remains a central focus in movement analysis, the emphasis has shifted over time. Technological advances have significantly enhanced motion analysis, with trending topics in each 5-year period.
    Keywords:  Abstracts; Analysis; Congress; Movement; Text mining
    DOI:  https://doi.org/10.1016/j.gaitpost.2025.04.023
  69. Braz J Phys Ther. 2025 Apr 28. pii: S1413-3555(25)00037-1. [Epub ahead of print]29(4): 101208
    "Go neurological physical therapy research, go"! Volume and methodological quality of neurological physical therapy: A 63-year PEDro database analyses.
    Julia Mafra Vasconcelos, Yasmine Guimarães Viana, Marina de Barros Pinheiro, Larissa Tavares Aguiar, Janaine Cunha Polese.
       BACKGROUND: Two decades ago, more than 200 randomized controlled trials (RCTs) of neurological physical therapy interventions in adults and pediatric populations were identified from 1958 to 2000, with half rated moderate to high quality on the Physiotherapy Evidence Database (PEDro) scale. Does the current panorama remain the same?
    OBJECTIVE: To investigate the changes in volume and quality of RCT of neurological physical therapy in adults and paediatrics indexed in the PEDro database between 1958 to 2021. In addition, to investigate if there is a relationship between journal impact factor and methodological quality.
    METHODS: All RCTs of neurological physical therapy in adults and pediatrics indexed in PEDro between 1958-2021 were included. Descriptive statistics described trial volume, quality, and trends over the years. Spearman's rho correlation test assessed the association between methodological quality and journal ranking (Journal Impact Factor (JIF) and Journal Citation Indication (JCI)).
    RESULTS: A total of 6291 RCTs of neurological physical therapy in adults and pediatrics were indexed in PEDro between 1958-2021, with a mean PEDro scale score of 5.3/10 (SD 1.6). The quality of RCTs improved over time, with a mean score of 5.7/10 (SD 1.4) for RCTs published between 2018-2021, compared to 1/10 between 1962-1965. A weak and significant relationship was found between methodological quality and JIF (r=0.153; p<0.001) and JCI (r=0.146; p<0.001).
    CONCLUSION: There is a large and growing volume of RCTs on neurological physical therapy in adults and pediatrics indexed in PEDro, with increasing quality over time, though still moderate. Journal ranking should not be used for selecting high quality RCTs.
    Keywords:  Evidence-based practice; Randomized controlled trials as topic; Research methodology
    DOI:  https://doi.org/10.1016/j.bjpt.2025.101208
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