bims-evares Biomed News
on Evaluation of research
Issue of 2025–04–20
88 papers selected by
Thomas Krichel, Open Library Society
  1. Thirty-Five Years of Knowledge in Transcultural Nursing: A Bibliometric Analysis of Journal of Transcultural Nursing.
  2. Patterns and Trends in Global Nursing Robotics Research: A Bibliometric Study.
  3. Research trends of nanomaterials in Helicobacter pylori: a bibliometric analysis from 2003 to 2023.
  4. Global research trends of home pharmaceutical care: a bibliometric analysis via CiteSpace.
  5. Advanced Practice Nursing: A Bibliometric and Visualization Analysis (1992-2023).
  6. Top 100 most-cited articles on pelvic organ prolapse: a visualization and bibliometric analysis.
  7. Bibliometric analysis and description of research trends on nutritional management in Alzheimer's disease patients (1988-2024).
  8. Research hotspots and frontier analysis on Mendelian randomization in osteoporosis-related fields: A review based on bibliometric and visual analysis.
  9. Research trends in essential thrombocythemia from 2001 to 2024: a bibliometric analysis.
  10. Recent research landscape on chitosan-mineral-based composites for wastewater treatment: a comprehensive bibliometric analysis (2014-2024).
  11. Bibliometric analysis and visualization of research trends in radiation dermatitis in the past twenty years.
  12. Trends in nanomedicine for colorectal cancer treatment: Bibliometric and visualization analysis (2010-2024).
  13. Research Hotspots and Trends of Virtual Reality Intervention for Stroke: Bibliometric Analysis.
  14. Research trends and hot spots in the prevention and management of radiation dermatitis: a bibliometric analysis based on CiteSpace.
  15. Global Insights and Key Trends in Physical Literacy Research: A Bibliometric Analysis and Literature Review from 2007 to 2024.
  16. Complementary Repair Therapy as a Trending Topic in Discogenic Pain: A Bibliometric Study Over the Past 40 Years.
  17. Research mapping of cannabinoids and endocannabinoid system in cancer over the past three decades: insights from bibliometric analysis.
  18. The most cited publications on snowboarding-related head injuries, concussions, and injury distribution.
  19. Investigation into the Synthetic Strategies of Melamine-Based Porous Polymeric Materials: A Bibliometric Analysis.
  20. Research trends and hotspots evolution of nerve decompression: a bibliometric analysis from 2005 to 2024.
  21. Online learning in nursing education: A 21st century bibliometric analysis.
  22. Emerging trends and hotspots in chronic obstructive pulmonary disease and oxidative stress: a bibliometric and visualized analysis from 2010 to 2024.
  23. Insomnia Comorbid With Depression: A Bibliometric and Visualized Analysis of Research Trends and Hotspots From 2000 to 2024.
  24. Trends and Hotspots in Nursing Theory Research Published from 1990 to 2022: A Web of Science-Based Bibliometric Analysis.
  25. A bibliometric analysis of augmented reality and mixed reality applied in minimally invasive surgery.
  26. Combining with immunotherapy is an emerging trend for local treatment of colorectal cancer liver metastases: a bibliometric analysis.
  27. Neoadjuvant therapy for colorectal cancer from 2015 to 2024: a visual analysis and bibliometric analysis.
  28. Bibliometric analysis of multimodal analgesia research in the perioperative period: trends, contributions, and emerging areas (2013-2023).
  29. Global trends and insights of telesurgery research: a bibliometric analysis of publications since the 21st century.
  30. Inflammatory bowel disease therapeutics: a bibliometric analysis of tofacitinib research in ulcerative colitis.
  31. Global research frontiers and thematic trends in opioid-free anesthesia over the past 20 years: a bibliometric analysis.
  32. Global research trends in obesity-related asthma (2004-2023): a bibliometric analysis.
  33. Artificial intelligence-assisted multimodal imaging for the clinical applications of breast cancer: a bibliometric analysis.
  34. A bibliometric analysis of the current status of salivary gland tumors.
  35. Hotspots and scientometrics in gallbladder cancer surgery research: a bibliometric and visualization analysis (2014-2024).
  36. Pulmonary fibrosis complicated by lung cancer: bibliometric analysis from 2004 to 2024 - research status, trends and future directions.
  37. Bibliometric study of research trends in dysphagia complicating following anterior cervical spine surgery.
  38. From obesity to inflammation: emerging frontiers in prostate cancer and metabolic syndrome studies.
  39. Study on the potential capacity of cake fertilizer agricultural solid emission reduction and soil improvement based on CiteSpace.
  40. The status and hotspot analysis of research on extracellular vesicles and osteoarthritis: a bibliometric analysis.
  41. Emerging Insights in Thyroid Eye Disease Research from 2010 to 2022: Trends, Hot Spots, and Research Situation.
  42. B vitamins and colorectal cancer: exploring research hotspots and frontiers from a bibliometric and visual analysis (1994-2024).
  43. A Scientometric Perspective on Stigma Research in Medicine: A Bibliometric Review.
  44. Supply chain resilience from the maritime transportation perspective: A bibliometric analysis and research directions.
  45. Insights into the Technological Evolution and Research Trends of Mobile Health: Bibliometric Analysis.
  46. Mental Health of Nursing Students: A Bibliometric Review Based on CiteSpace Visual Analysis.
  47. Global Collaborative Trends in Otolaryngology Research: U.S. Partnerships With Low-, Middle-, and Other High-Income Countries.
  48. Synapses-associated research in Parkinson's disease: an explored trends analysis.
  49. The rising influence of lipid metabolism in lung cancer: a global research perspective.
  50. Knowledge Mapping and Global Research Trends of Ginseng Polysaccharides: a Bibliometric Analysis with Visualizations from 1985 to 2023.
  51. Bibliometric and visual analysis in the field of macrophages in Traditional Chinese Medicine from 2003 to 2023.
  52. Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview.
  53. A scientometric analysis and visualization of research on fatty liver diseases in Iran from 2003 to 2023.
  54. Clinical leadership in nursing in an ever-changing world: a bibliometric analysis.
  55. Global trends in research on eating behaviors among overweight/obese children and adolescents: a bibliometric study from 2003 to 2023.
  56. The insight to history and trends of transient elastography for assessing liver fibrosis-a bibliometric analysis.
  57. Comment on "A bibliometric analysis of primary health care publication trends in the Asia-Pacific region from 2011 to 2023".
  58. Research dynamics and drug treatment of renal fibrosis from a mitochondrial perspective: a historical text data analysis based on bibliometrics.
  59. Mapping the scientific research on exercise therapy for Alzheimer's disease: a scientometric study of hotspots and emerging trends.
  60. What Sets Indexed Orthopaedic Journals Apart? A Comparative Analysis of Quality Metrics Between Indexed Orthopaedic Journals and Nonindexed Orthopaedic Journals.
  61. Evaluating Bibliometrics Reviews: A Practical Guide for Peer Review and Critical Reading.
  62. Unveiling disparity: A call to action for gender diversity in anatomy journal editorial teams.
  63. Mapping the research landscape of mHealth and technology in pediatric chronic illness: a bibliometric study.
  64. Chemotherapy-Induced Bone Marrow Suppression: A Bibliometrics Analysis.
  65. A scientometric study on research trends and characteristics of ameloblastoma.
  66. A scientometric study on research trends and characteristics of burning mouth syndrome.
  67. Advances and Applications of Micro- and Mesofluidic Systems.
  68. Gap of Research to Practice in IC/BPS: A Scientometric Study of Available Evidence.
  69. Citation practices in applied linguistics: a comparative study of Chinese expert and novice authors.
  70. A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity.
  71. Sarcopenia as a Prognostic Factor for the Outcomes of Surgical Treatment of Colorectal Carcinoma.
  72. Representation of women in executive and academic roles within scientific societies in the field of European Endodontology.
  73. Retractions of COVID-19-related Research Publications During and After the Pandemic.
  74. Trends and future directions in childhood obesity research in the Nordic countries: a scientometric review.
  75. A scientometric study on research trends and characteristics of Behçet's disease.
  76. Female Representation in Ophthalmic Oncology and Pathology: An Analysis of Scholarship and Leadership.
  77. OREF Resident Research Symposia: An Important Pipeline for Prospective Orthopaedic Surgeon-Scientists.
  78. IoT Sensing for Advanced Irrigation Management: A Systematic Review of Trends, Challenges, and Future Prospects.
  79. These are the most-cited research papers of all time.
  80. Geographical and disciplinary coverage of open access journals: OpenAlex, Scopus, and WoS.
  81. Predictors for Publication of Specialty Theses in the Field of Infectious Diseases and Clinical Microbiology.
  82. From Cow to Climate-Tracing the Path of Dairy Sustainability: Unveiling the Impact on Sustainable Development Goals Through Bibliometric and Literature Analyses.
  83. Research citations building trust in Wikipedia: Results from a survey of published authors.
  84. Cannabis-Bacteria Interaction: Trends in Secondary Metabolites, Biocontrol, and By-products.
  85. Science's golden oldies: the decades-old research papers still heavily cited today.
  86. Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus: Bibliometric Analysis and Literature Review.
  87. Psychodermatology: a bibliometric perspective on dermatologic and psychiatric intersections.
  88. Mobile health (mHealth) technologies for fall prevention among older adults in low-middle income countries: bibliometrics, network analysis and integrative review.
  1. J Transcult Nurs. 2025 Apr 12. 10436596251330291
    Thirty-Five Years of Knowledge in Transcultural Nursing: A Bibliometric Analysis of Journal of Transcultural Nursing.
    Turgay Yalcinkaya, Erkan Ünsal.
       INTRODUCTION: This bibliometric analysis aims to examine articles published in Journal of Transcultural Nursing (JTCN), between 1989 and 2024.
    METHOD: This study analyzed 1,675 JTCN publications from 1989 to 2024 using Scopus as a data source. Performance analysis and scientific mapping techniques were used for bibliometric metadology. Analyses were performed with VOSviewer and Bibliometrix software.
    RESULTS: In total, 1,675 articles were included in the study. The most prolific authors are Leininger, M., Boyle, J.S., Pacquiao, D.F., and Zoucha, R. The leading countries in terms of number of publications are the United States, Canada, and Australia. According to the co-occurrence analysis, six research themes emerged. In addition, it was determined that "nursing care," "COVID-19," "social determinants of health," "health equity," and "refugees" were trending topics.
    DISCUSSION: Our findings can provide nurses and academicians with ideas on the subject by identifying trending topics and leading researchers in JTCN.
    Keywords:  Journal of Transcultural Nursing; bibliometric analysis; bibliometrics; transcultural nursing
    DOI:  https://doi.org/10.1177/10436596251330291
  2. J Nurs Manag. 2025 ;2025 7853870
    Patterns and Trends in Global Nursing Robotics Research: A Bibliometric Study.
    Shan Zhang, Lu Liu, Tingting Peng, Shu Ding.
      Aims: The present study aimed to investigate the trends and research status of global nursing robot research. Background: The global aging population has intensified the demand for caregiving services, highlighting the need for innovative solutions like nursing robots to address caregiver shortages and enhance healthcare efficiency. A bibliometric analysis of nursing robots from 2014 to 2024 are noteworthy but limited. Methods: We searched the Web of Science database for relevant articles concerning nursing robots, published between January 1, 2014 to October 30, 2024. Data collected include: the number of publications, countries, institutions, authors, journals, reference, and keywords. CiteSpace were used to conduct the bibliometric analysis. Results: The analysis included a total of 696 publications, which were produced by 165 institutions from 66 countries and involved 243 authors. The publications exhibited a generally increasing trend with fluctuations over time. The United States of America contributed the majority of articles, with 187 publications accounting for 26.87% of the total. Griffith University from Australia led the institutions with 11 publications, representing 1.58% of the overall count. The International Journal of Social Robotics was the most prolific in publishing articles on nursing robots, with 162 publications. Through the analysis of timeline graph and burst terms, we identified technology, functionality, and impact of nursing robots as research hotspots. The application of social robots in patient care and advancements in team collaboration during robot-assisted surgery are potential emerging research directions. Conclusions: This study presents an overview of the nursing robot research landscape over the past decade. This research offer valuable insights and direction for future trends and research trajectories in the domain of nursing robots. Implications for Nursing Management: Nursing administrators can appropriately apply nursing robots to assist in improving nursing efficiency, thereby freeing up nurses' time to focus on more complex patient care.
    Keywords:  aging; analysis; bibliometrics; nursing; robotics
    DOI:  https://doi.org/10.1155/jonm/7853870
  3. Front Pharmacol. 2025 ;16 1546395
    Research trends of nanomaterials in Helicobacter pylori: a bibliometric analysis from 2003 to 2023.
    Yeqing Lei, Tao Chen, Qin Du, Weihua Yu.
       Background: H. pylori infects approximately half of the global population and is associated with numerous diseases, posing a significant public health challenge. Recently, there has been increasing focus on researching nanomaterials for H. pylori. This study aims to visually evaluate the current status and trends of nanomaterials in H. pylori research by bibliometric analysis.
    Methods: H. pylori-related nanomaterials publications were retrieved from WoSCC and articles meeting the criteria were included in the analysis. The data was analyzed by Microsoft Excel, CiteSpace, and VOS viewer.
    Results: This bibliometric analysis included 177 publications on H. pylori and nanomaterials from 2003 to 2023. The study revealed a consistent increase in publications and citations. China leads in the number of publications, citation frequency, and maintains close relations with other countries. The International Journal of Biological Macromolecules and Biomaterials are the leading journals. Yu-hsin Lin is the most contributory scholar. Recent years have seen the special nanoparticles and targeted drug delivery remain a burgeoning research area.
    Conclusion: We conducted a bibliometric analysis of H. pylori-related nanomaterials research and identified the current research direction and frontier in the application of nanomaterials for H. pylori.
    Keywords:  Helicobacter pylori; bibliometric analysis; nanomaterial; research trend; treatment
    DOI:  https://doi.org/10.3389/fphar.2025.1546395
  4. Front Med (Lausanne). 2025 ;12 1489720
    Global research trends of home pharmaceutical care: a bibliometric analysis via CiteSpace.
    Qingfang Wu, Xiaorong Feng, Chao Shen, Ying Liu, Shiwen Yang, Na Su.
       Background: This study aimed to systematically review the research on home pharmaceutical care and to identify emerging trends and research hotspots using bibliometric methods.
    Methods: Publications related to home pharmaceutical care, published from inception to 6 February 2025, were extracted from the Web of Science Core Collection (WoSCC). The bibliometric tool CiteSpace was employed to analyze various metrics, including the number of publications, contributing countries, institutions, authors, keywords, cited references, and research trends in the field of home pharmaceutical care.
    Results: A total of 812 relevant articles were retrieved from the WoSCC. The most prolific contributors were Hughes CM, Nishtala, PS, and Lapane KL. The United States emerged as the leading country in the field, with Queen's University Belfast identified as the most productive institution. The keyword with the highest frequency was "pharmaceutical care." The research hotspots in this field were centered around "polypharmacy," "medication reconciliation," and "drug-related problems."
    Conclusion: This study utilized CiteSpace to analyze research trends and hotspots in the field of home pharmaceutical care. The findings suggest that "polypharmacy" and "care homes" are likely to become focal points of future research. Additionally, the development of research in developing countries lags behind that in developed countries. Therefore, it is crucial for developing countries to learn from the advances made by developed nations in this field, and to foster greater international collaboration and research efforts.
    Keywords:  CiteSpace; bibliometric analysis; family pharmacist; home pharmaceutical care; visualization analysis
    DOI:  https://doi.org/10.3389/fmed.2025.1489720
  5. J Multidiscip Healthc. 2025 ;18 1947-1958
    Advanced Practice Nursing: A Bibliometric and Visualization Analysis (1992-2023).
    Yan Wen, Yue Hu, Wanting Cai, Qian Cao.
       Background: Advanced Practice Nurses (APNs) have become essential to healthcare systems, but the development of research related to APNs has been uneven. Understanding publication trends in this area can provide valuable insights into gaps in the literature and practice.
    Objective: This study aimed to analyze the publication patterns of APNs in the field of nursing through bibliometric methods.
    Methods: This study is a descriptive bibliometric study. Data were collected from the Web of Science database in January 2024 and analyzed using VOSviewer software.
    Results: The search strategy identified 595 publications authored by 1843 researchers across 44 countries and published in 88 different journals spanning 1992 to 2023. Analysis reveals several key trends in APN research: (a) a significant growth in publications, particularly in the past three years; (b) predominant contributions from scholars in a select number of countries; (c) limited collaboration among countries, institutions, and authors; and (d) a focus on key themes such as APN education frameworks and clinical competencies.
    Conclusion: The existing body of literature on APN within the nursing field remains limited. Future research should aim to focus on fostering greater international collaboration among researchers and encouraging the adoption of the APN role in developing countries. These efforts could significantly enhance healthcare services and improve patient health outcomes globally.
    Keywords:  advanced practice nurse; bibliometric analysis; nursing field; visualization analysis; web of science
    DOI:  https://doi.org/10.2147/JMDH.S511007
  6. Front Surg. 2025 ;12 1485426
    Top 100 most-cited articles on pelvic organ prolapse: a visualization and bibliometric analysis.
    Lu Yang, Qin Tao, Huaye Wu, Litong Yin, Xuemei Wu, Ying Xiong, Xiaoqin Gan, Yonghong Lin, Xia Yu.
       Introduction: Bibliometric analysis is a scientometric method that allows the quantitative analysis of publications. This study used the Web of Science database to perform a bibliometric analysis of the 100 most-cited articles in the field of pelvic organ prolapse (POP) to identify the key research themes and emerging topics within this area.
    Methods: We collected pertinent publications from the Web of Science Core Collection (WoSCC). The search was conducted using the following keywords: "pelvic organ prolapse", "pelvic organ prolapse" or "pelvic organ prolapses". The search included all publication dates up to June 27, 2024, without any article type restrictions, and the articles were sorted based on their citation count. The top 100 articles with the most citations were included in the subsequent analyses. Several tools, including the Bibliometrix program in R, CiteSpace software, the Online Analysis Platform of Literature Metrology (https://bibliometric.com), and an online interface by Bibliometrix, were used to analyze the data.
    Results: The top 100 most cited articles in the field of POP were cited 26,894 times in total. These articles were published between 1993 and 2019, and the majority of them were published during the 10-year period from 2001 to 2010. The United States and the University of California, San Francisco, produced the most publications on this topic. The American Journal of Obstetrics and Gynecology had the greatest influence on POP research. The most prolific author in this field was Barber MD (n = 7). Epidemiological research and treatment, particularly in the area of tissue engineering, were the main focus and current trends in POP research.
    Conclusion: This study revealed key research areas and current research hotspots for POP, with a particular focus on epidemiological studies and surgical interventions, especially in the field of tissue engineering. It is suggested that the future research in this field should pay more attention to epidemiological research and treatment, so as to better understand the risk factors of the disease and the characteristics of the affected population, and expect high-quality curative effect and prevention.
    Keywords:  CiteSpace; bibliometric; pelvic organ prolapse; research directions; visualization
    DOI:  https://doi.org/10.3389/fsurg.2025.1485426
  7. Front Nutr. 2025 ;12 1545951
    Bibliometric analysis and description of research trends on nutritional management in Alzheimer's disease patients (1988-2024).
    Chenchen Meng, Bei Li, Zhaoxia Wang, Qing Peng.
       Background: Alzheimer's disease (AD) is a severe neurodegenerative disorder. Nutritional management has been recognized as a potential therapeutic approach to mitigate AD progression. This study aimed to analyze the bibliometric characteristics and research trends of publications on nutritional management in AD.
    Methods: A systematic search was conducted on the Web of Science Core Collection database to identify publications related to nutritional management in AD from 1988 to 2024. Bibliometric analysis was performed using VOSviewers (V 1.6.20), CiteSpace (V 6.3.R1) and R 4.3.3.
    Results: A total of 554 publications from 311 countries led by the USA were identified. The number of publications has increased annually. The most cited article discussed the role of diet in providing antioxidants to combat oxidative stress in neurodegenerative diseases. The University of California system published the most articles, and Rush University had the most international collaborations. These publications came from 3,298 authors, among which Mattson MP had the highest total publications and citations. The Journal of Alzheimer's Disease published the most articles and received the most citations. Keywords analysis revealed evolving trends, with early emphasis on "precursor protein" and later shifts to "dietary restriction," and more recently, "insulin resistance" and "synaptic plasticity." Emerging keywords include "obesity," "cognitive impairment" and "association."
    Conclusion: This study represents the first summary of research trends in AD nutritional management. Future research is likely to focus on the associations between nutrition, insulin resistance, synaptic plasticity, and cognitive impairment in AD patients. This information provides valuable insights for scholars and practitioners in the field.
    Keywords:  Alzheimer’s disease; bibliometrics; diet; nutritional management; publication
    DOI:  https://doi.org/10.3389/fnut.2025.1545951
  8. Medicine (Baltimore). 2025 Apr 11. 104(15): e41961
    Research hotspots and frontier analysis on Mendelian randomization in osteoporosis-related fields: A review based on bibliometric and visual analysis.
    Qingqing Zeng, Sijie Gui, Zhuolan Li, Fei Wu, Dan Peng, Guqing Zeng.
      This research seeks to thoroughly examine the present state and research hotspots in Mendelian randomization (MR) in osteoporosis (OP)-related fields, providing a reference for future research directions in this area. Following an exhaustive search of the Web of Science Core Collection database, our analysis utilized citation statistics for osteoporosis studies conducted from January 1, 2007, through March 15, 2024. Bibliometric and visual analyses were conducted using two online analysis systems, CiteSpace and VOSviewer. The analysis included a variety of dimensions, including the distribution of citations, authorship, published journals, year of publication, countries, co-occurrence keywords and keyword clustering. From 2007 to 2024, the number of publications in MR in OP-related fields showed an overall increased. High-impact publications and leading contributors were primarily from China, followed by the USA and England. The journal with the largest number of publications in MR in OP-related fields is the Journal of Bone and Mineral Research. Risk factor research, genome-wide associations, meta-analysis, fractures, and gene loci were the main research hotspots. Interdisciplinary integration, MR research combined with data from clinical trials and observational studies, represents the future development trend. Research on MR in OP-related fields has mainly been conducted in China, the USA, and England. The research hotspots were aimed at exploring the causative between risk factors and OP. Future studies are likely to center on multidisciplinary integration.
    Keywords:  bibliometric; hotspots; mendelian randomization; osteoporosis; visual analysis
    DOI:  https://doi.org/10.1097/MD.0000000000041961
  9. Discov Oncol. 2025 Apr 15. 16(1): 528
    Research trends in essential thrombocythemia from 2001 to 2024: a bibliometric analysis.
    Yiming Pan, Lingyan Chen, Qun Jiang, Dejian Chen, Yanqin Wu, Li Hou, Haiyan Lang, Jun Yan.
       OBJECTIVE: This study aims to conduct a comprehensive bibliometric analysis of ET research, focusing on contributions from authors, institutions, and countries or regions, while mapping collaboration networks. Furthermore, it identifies development trends to provide insights for future research.
    METHODS: A bibliometric analysis of ET-related publications (2001-2024) was conducted using data from the Web of Science Core Collection, focusing on publication trends, co-authorship networks, co-citation relationships, and citation bursts.
    RESULTS: A total of 4,297 studies published in 778 journals were included in the analysis. ET research has grown rapidly, with major contributions from researchers in the United States and Europe, particularly through extensive collaborations. Leading figures such as Ayalew Tefferi and Alessandro M. Vannucchi have driven advances in ET classification, molecular mechanisms, and targeted therapies. The discovery of driver mutations, such as JAK2, has revolutionized the diagnostic and therapeutic approaches to ET. Research focus has shifted from clinical morphological diagnosis to molecular diagnostics, with the field now entering the era of targeted therapies. However, the heterogeneity of ET, the limitations of targeted therapies, particularly the lack of management experience and data for high-risk and special populations, as well as the incomplete understanding of the role of inflammation in the disease mechanism, continue to hinder both clinical and scientific progress in ET research.
    CONCLUSIONS: Bibliometric analysis demonstrates significant advances in ET research, particularly in molecular pathology and targeted therapies. Future research should address ET heterogeneity, optimize management of high-risk and special populations, overcome the limitations of targeted therapies, and further elucidate the role of inflammation to achieve individualized precision therapy.
    Keywords:  Bibliometric analysis; CiteSpace; Essential thrombocythemia; Inflammation; Myeloproliterative neoplasms; Research trends; VOSviewer
    DOI:  https://doi.org/10.1007/s12672-025-02232-9
  10. Environ Sci Pollut Res Int. 2025 Apr 16.
    Recent research landscape on chitosan-mineral-based composites for wastewater treatment: a comprehensive bibliometric analysis (2014-2024).
    Fatiha Tafraout, Jalal Isaad.
      Chitosan-mineral composites are emerging as potential adsorbent materials for wastewater treatment because they are eco-friendly, cost-effective, and versatile for removing contaminants like heavy metals and dyes. Their rapid development in research requires a systematic analysis of research gaps, trends, and contributions at a global level to guide future innovations. This bibliometric study investigates and analyzes 1690 documents retrieved from the Web of Science published between 2014 and 2024, focusing on chitosan-mineral composites for wastewater treatment. We used Bibliometrix (R package), HistCite, and VOSviewer tools to examine publication trends, authorship, collaborations between countries, and networks of keywords. Key parameters included an important annual growth rate of 16.86%, 32.12 average citations per document, and contributions from 480 sources. The field has grown exponentially since 2018, with China, India, and Iran leading the research output. High citation rates (avg. 32.12 per document) reflect a strong academic impact, while 26.78% international collaboration underscores global engagement. As such, the analysis of keywords present in these papers found predominant themes that have driven research, namely adsorption mechanisms and composite functionalization (i.e., magnetic hybrids). Novel trends involve clay-chitosan synergies and nano-reinforced composites for pollutant-specific removal.
    Keywords:  Bibliometric analysis; Bibliometrix (R package); Chitosan; Composites; HistCite; Mineral; VOSviewer; Wastewater
    DOI:  https://doi.org/10.1007/s11356-025-36387-3
  11. Radiat Oncol. 2025 Apr 15. 20(1): 54
    Bibliometric analysis and visualization of research trends in radiation dermatitis in the past twenty years.
    Xinyi Zhang, Yuai Xiao, Ang Li, Yuchong Wang, Jianguo Xu, Kexin Chen, Haoyuan Zheng, Minliang Wu, Chunyu Xue.
       OBJECTIVES: This study aims to explore the most influential countries/regions, institutions, journals, authors, keywords, and trends in the study of the mechanism and treatments of radiation dermatitis (RD) from 2003 to 2023 using bibliometric analysis.
    METHODS: The literature associated with RD was retrieved from the Web of Science Core Collection, only articles and reviews in English were included. Individual articles were reviewed to identify the authorship, published journal, journal impact factor, institution and country of origin, and year of publication.
    RESULTS: A total of 6,453 authors from 1,605 institutions in 64 countries/regions published 1,062 RD-related literature. The United States was the most productive country. The Unicancer in France was the institution that published the majority of articles on RD. Edward Chow was the most productive author and Supportive Care in Cancer contributed the most articles. Advanced head and neck cancer is the most common cause of RD. The mechanism research mainly focused on nitric oxide, oxidative stress, and apoptosis in recent years, and Mepitel film, Mepilex Lite, and PBMT were the main preventive and therapeutic measures for RD.
    CONCLUSION: Our bibliometric studies provide a thorough overview of RD and valuable insights and ideas for scholars in this discipline.
    Keywords:  Bibliometrics; Radiation dermatitis; Randomized controlled trial; Research trend
    DOI:  https://doi.org/10.1186/s13014-025-02629-4
  12. World J Gastrointest Oncol. 2025 Apr 15. 17(4): 102438
    Trends in nanomedicine for colorectal cancer treatment: Bibliometric and visualization analysis (2010-2024).
    Yu-Ren Zhang, Hui-Rong Zhu, Hao-Ran Li, Yue-Lei Cheng, Sun-Hu Yang, Su-Ling Sun, Zheng Wang.
       BACKGROUND: Recently, numerous studies have reported the application of nanomedicines in colorectal cancer treatment. However, no systematic bibliometric analysis has been conducted to examine the potential and mechanisms of action of nanomedicine in this context. Such an analysis may provide a comprehensive overview of the current research landscape, identify emerging trends, and highlight key areas for future investigation.
    AIM: To describe the current global research landscape on the application of nanomedicine in colorectal cancer treatment.
    METHODS: The Web of Science Core Collection database was searched for literature published from January 1, 2010, to August 7, 2024, focusing on the application of nanomedicine in colorectal cancer treatment. Bibliometric analysis and visualization mapping of countries, institutions, authors, keywords, references of the relevant research literature were conducted using CiteSpace (6.2R6), VOSviewer (1.6.20), and bibliometrix (based on R 4.3.2).
    RESULTS: A total of 3598 articles were included, with a rapid increase in publication volume starting from 2010. China published the most papers on this topic, followed by the United States and India. The United States emerged as the central country in this field, and the Egyptian Knowledge Bank and Chinese Academy of Sciences were the institutions with the highest number of publications. The Chinese Academy of Sciences exhibited the highest centrality. The most prolific author was Zhang Y, whereas Siegel RL was the most cited author, and Li Y had the highest H-index. The International Journal of Nanomedicine had the most publications and Biomaterials received the most citations. Keyword co-occurrence analysis identified 11837 keywords grouped into 13 clusters with 15 high-frequency highlighted keywords. The top three keyword clusters were "0 colorectal cancer", "1 drug delivery", and "2 delivery", with the top three keywords being "nanoparticles", "colorectal cancer", and "drug delivery".
    CONCLUSION: Research on nanomedicine for colorectal cancer has surged since 2010, focusing on "nanoparticles" and "drug delivery". Future studies should investigate nanomaterial stability and target-specific drug release.
    Keywords:  Bibliometric; Citespace; Colorectal cancer; Hotspot; Nanomedicine; VOSviewer
    DOI:  https://doi.org/10.4251/wjgo.v17.i4.102438
  13. JMIR Serious Games. 2025 Apr 16. 13 e65993
    Research Hotspots and Trends of Virtual Reality Intervention for Stroke: Bibliometric Analysis.
    Yixin Wei, Yuan Chen, Runting Ma, Yitong Qiu, Wei Su, Li Zhang, Qiang Gao.
       Background: Virtual reality (VR) is a rapidly developing technology that has gained significant traction in the treatment and rehabilitation of individuals with stroke. Research on VR-based stroke treatment has garnered increasing attention.
    Objective: The aim of this study is to present a bibliometric analysis of VR for stroke studies to identify the application status, research hotspots, and emerging trends and guide future scientific research.
    Methods: We included studies and reviews on the topic of VR-based stroke treatment and rehabilitation from 1999 to 2023 were retrieved from Web of Science Core Collection database. Citespace 6.3.1 and VOSviewer 1.6.20 software was used for the visual analysis of publications, institutions, authors, journals, citations, and Scimago Graphica software was used for the geographic visualization of published countries or regions.
    Results: Our study analyzed 1171 papers on VR-based stroke rehabilitation published between 1999 and 2023, revealing a gradual increase in annual publications over the past 2 decades, peaking at 154 in 2022. North America and Western Europe were identified as major contributors, with significant input from their institutions, researchers, and publications. The Journal of NeuroEngineering and Rehabilitation emerged as the leading journal in this field, while Calabrò Rocco Salvatore was recognized as the most prolific author, focusing on the neurophysiological impacts of VR on patients with stroke. Keywords with notable citation bursts, such as "environment," "trial," "arm," and "motor learning," highlighted the core research themes in this domain.
    Conclusions: Our study provides valuable insights into the current research hotspots and emerging trends in VR-based stroke treatment and rehabilitation. Current research primarily focuses on evaluating the effectiveness of VR in improving upper limb function and balance in patients with stroke. Future directions are shifting towards integrating VR with rehabilitation techniques, such as physiotherapy and occupational therapy, while advancements in VR technology continue to garner increasing attention.
    Keywords:  bibliometric analysis; hotspots; research trends; stroke; virtual reality
    DOI:  https://doi.org/10.2196/65993
  14. Radiat Oncol. 2025 Apr 16. 20(1): 55
    Research trends and hot spots in the prevention and management of radiation dermatitis: a bibliometric analysis based on CiteSpace.
    Lu Zhang, Lian Liu, Fang Li, Peijuan Chen, Feng Ye.
       OBJECTIVE: This study sought to examine the current state and explore the key areas and emerging trends in radiation dermatitis prevention and management through bibliometric analysis, with the goal of providing valuable insights for future research endeavors.
    METHODS: This study analyzed all publications on radiation dermatitis prevention and management from the Web of Science (WOS) core database up to 2024. The CiteSpace software was utilized to visualize authors, countries/regions, publishing institutions, keywords, co-cited documents, hot spots, and research frontiers.
    RESULTS: A total of 459 articles (1995-2024) were identified, with the overall number of publications demonstrating an increasing trend. The United States (125) produced the highest number of publications, followed by China (73) and Canada (45). Key research topics encompass breast cancer, head and neck cancer, acute radiation dermatitis, and radiation recall dermatitis. Double-blind clinical trials constitute the primary research methodology. The main research areas in this field focus on the role of radiotherapy dose fractionation modalities, atmospheric pressure cold plasma, hyperbaric oxygen therapy (HBOT), aloe vera, biomodulation therapy, and biological dressings in the prevention and management of radiation dermatitis.
    CONCLUSION: This comprehensive bibliometric analysis reveals that risk prediction, assessment tools, and the efficacy of radiodermatitis are prominent research topics in the field. These areas are currently experiencing rapid growth and warrant further attention from researchers.
    Keywords:  Bibliometrics; Management; Prevention; Radiation dermatitis; Visual analysis
    DOI:  https://doi.org/10.1186/s13014-025-02628-5
  15. J Multidiscip Healthc. 2025 ;18 2039-2055
    Global Insights and Key Trends in Physical Literacy Research: A Bibliometric Analysis and Literature Review from 2007 to 2024.
    Hongsheng Qian, Xueyan Ren, Huidi Wang, Yu Zou.
       Background: Extensive research has been carried out on physical literacy (PL) over the past decades. Nonetheless, no comprehensive bibliometric analysis of relevant publications has been performed. In this study, we conducted a comprehensive bibliometric review of studies on PL to track research trends and highlight current research hotspots.
    Methods: The Web of Science Core Collection (WoSCC) database was selected to retrieve publications from inception to 2024 on PL. Articles and reviews written in English with PL as the main topic were included. VOSviewer and CiteSpace software were used to perform analysis and visualization of scientific productivity and emerging trends.
    Results: A total of 710 publications were retrieved. Canada dominated this field with the most publications (188). The institution and author with the largest number of articles were The Chinese University of Hong Kong (46 publications) and Cairney John (35 publications), respectively. BMC Public Health was the most influential journal with 41 articles and 1214 citations. Publications were primarily distributed across journals in sports science, education, public health, and other allied disciplines. Five topics were identified by reference co-citation analysis and keyword analysis: the definition of PL, PL in education, the association of PL, the intervention of PL, and the measurement and assessment of PL. The measurement, assessment and intervention of PL may become the frontiers.
    Conclusion: PL research has witnessed growing scholarly interest over the past 18 years. The concept of PL lacks consensus, and the necessity of establishing a unified conceptualization remains contentious. Most existing PL measurement tools lack comprehensiveness in capturing conceptual components, highlighting the need for established instruments aligned with its theoretical foundations. PL interventions vary in design and effectiveness, making it essential to identify effective strategies. Furthermore, multidisciplinary collaboration is imperative. This study could offer strategic guidance for identifying potential collaborators and prioritizing research priorities.
    Keywords:  assessment; bibliometric review; intervention; measurement; physical literacy; visualization analysis
    DOI:  https://doi.org/10.2147/JMDH.S515715
  16. Health Sci Rep. 2025 Apr;8(4): e70664
    Complementary Repair Therapy as a Trending Topic in Discogenic Pain: A Bibliometric Study Over the Past 40 Years.
    Zhouyang Hu, Lijun Li, Zhipeng Xu, Jianjin Zhang, Guoxin Fan, Xiang Liao.
       Background and Aims: Bibliometric analysis has been frequently employed for visualizing trends within a particular scientific domain. The pain associated with discogenic origins has a significant impact on one's quality of life, but there is currently a lack of bibliometric analysis in the literature. Hence, this study aimed to examine related research in the field and identify the latest topics that are currently trending by conducting a bibliometric analysis.
    Methods: The Bibliometrix which developed in the statistical R-packages was used for the data analysis. All related eligible publications were identified, and studies published from 1982 to 2023 were extracted from the Web of Science database.
    Results: Disc repair, bone marrow cells, platelet-rich plasma, and the activation of inflammatory responses were identified as the trending topics after analyzing 977 journal articles. The most productive and influential journal was SPINE (Phila Pa 1976), which accounted for the largest publications and highest H index. The most productive and locally cited authors were Takahashi K., Ohtori S., and Aoki Y. from Chiba University. The top three productive and globally cited institutions were Chiba University, followed by University of California San Francisco and Korea University. The USA, China, and Japan were demonstrated as the most productive and globally cited countries.
    Conclusion: This study performed the first bibliometric analysis on discogenic pain and provided valuable insights into the latest trending topics in the field. Analysis reveals that recent research has primarily focused on complementary and regenerative approaches for repairing painful discs, as well as the role of inflammatory responses in disc pathology.
    Keywords:  bibliometric analysis; complementary repair; discogenic pain; hotspot; trending topic; web of science
    DOI:  https://doi.org/10.1002/hsr2.70664
  17. Front Pharmacol. 2025 ;16 1540619
    Research mapping of cannabinoids and endocannabinoid system in cancer over the past three decades: insights from bibliometric analysis.
    Yaqian Tan, Hui Xia, Qi Song.
       Background: The cannabinoids and endocannabinoid system are thought to play critical roles in multiple signaling pathways in organisms, and extensive evidence from preclinical studies indicated that cannabinoids and endocannabinoids displayed anticancer potential. This study aimed to summarize the research of cannabinoids and endocannabinoid system in cancer through bibliometric analysis.
    Methods: Relevant literature in the field of cannabinoids and endocannabinoid system in cancer published during 1995-2024 were collected from the Web of Science Core Collection database. VOSviewer and SCImago Graphica were applied to perform bibliometric analysis of countries, institutions, authors, journals, documents, and keywords.
    Results: A total of 3,052 publications were identified, and the global output exhibited a generally upward trend over the past 3 decades. The USA had the greatest number of publications and citations in this research field. Italian National Research Council led in terms of publication, while Complutense University of Madrid had the highest total citations. Vincenzo Di Marzo was the leading author in this field with the greatest number of publications and citations. The co-occurrence of keywords revealed that the research frontiers mainly included "cannabinoids", "endocannabinoid system", "cancer", "anandamide", "cannabidiol", "cannabinoid receptor", "apoptosis", and "proliferation".
    Conclusion: Our results revealed that the research of cannabinoids and endocannabinoid system in cancer would receive continuous attention. The USA and Italy have made remarkable contributions to this field, supported by their influential institutions and prolific scholars. The research emphasis has evolved from basic functional characterization to mechanistic exploration of disease pathways and translational applications within multidisciplinary framework.
    Keywords:  bibliometric analysis; cancer; cannabinoids; endocannabinoid; tumor; visualization
    DOI:  https://doi.org/10.3389/fphar.2025.1540619
  18. Phys Sportsmed. 2025 Apr 18. 1-8
    The most cited publications on snowboarding-related head injuries, concussions, and injury distribution.
    Benjamin D Gross, Avanish Yendluri, Niklas H Koehne, Amogh I Iyer, Akshar V Patel, Paul J Cagle, Robert L Parisien.
       OBJECTIVES: The purpose of this study was to identify the 50 most-cited publications relating to snowboarding and conduct a bibliometric analysis of the identified studies.
    METHODS: Clarivate Analytics Web of Science database was queried to identify all publication titles, abstracts, and keywords related to snowboarding. The resulting articles were sorted by total number of citations. Titles and abstracts were included based on their relevance to snowboarding. Once the 50 most cited articles were identified, each article was further analyzed to obtain author name, publication year, country of origin, journal name, article type, research topic, competition level, total number of citations, and the level of evidence. Citation density (total number of citations/years since publication) was calculated and recorded for each of the most-cited studies.
    RESULTS: The 50 most-cited articles were cited 4,123 times with an average of 82.5 citations per article. The most cited article was cited 212 times. The majority of articles came from 2 different countries, with the United States and Canada contributing 18 and 10 articles, respectively. The American Journal of Sports Medicine published the most articles (n = 11). The most studied topic was injury distribution (n = 25) followed by head injuries (n = 8). Recreational snowboarding was the most studied level of competition (n = 43).
    CONCLUSIONS: The 50 most-cited articles related to snowboarding are predominantly cohort and review studies from the United States and Canada, focusing on recreational athletes. These articles primarily detail the total anatomic distribution of snowboard-related injuries, particularly head injuries and concussions.
    Keywords:  Bibliometrics; concussions; snowboarding; sports injuries; traumatic brain injury
    DOI:  https://doi.org/10.1080/00913847.2025.2491991
  19. Polymers (Basel). 2025 Mar 24. pii: 868. [Epub ahead of print]17(7):
    Investigation into the Synthetic Strategies of Melamine-Based Porous Polymeric Materials: A Bibliometric Analysis.
    Nazeeha S Alkayal.
      Recent years have seen the rapid development of melamine-based porous organic polymers, a new category of porous material. This review paper comprehensively describes the progress and trends of melamine-based porous organic polymers by using bibliometric analysis. A total of 1397 publications published over the previous 15 years were extracted from the Web of Science Core Collection database. Also, cooperation between countries and affiliations and keyword co-occurrence were assessed with the aid of VOS viewer software 1.6.20. The findings suggested that this field of study is now rapidly evolving. From 41 articles in 2009 to 180 articles in 2022, the number of published articles has increased significantly. China was the most productive nation, publishing 863 articles with 61.78% contribution. The Chinese Academy of Sciences was the most productive organization, and Chinese author Qiang Li was the most productive individual. Keyword co-occurrence analysis identified major research hotspots, including the design of high-surface-area materials for adsorption, functionalization strategies to enhance materials' performance, and novel synthesis routes for structural control. Furthermore, this review systematically categorizes synthetic strategies based on the linkage structures between melamine and other building blocks, providing insights into state-of-the-art advancements and future research directions in the field.
    Keywords:  bibliometric; melamine; porous organic polymer; synthetic strategies
    DOI:  https://doi.org/10.3390/polym17070868
  20. World Neurosurg. 2025 Apr 10. pii: S1878-8750(25)00324-9. [Epub ahead of print] 123968
    Research trends and hotspots evolution of nerve decompression: a bibliometric analysis from 2005 to 2024.
    Hui Han, Sheng Wang, Hongyue Zhang, Jinlong Zheng, Danyan Song, Wenkui Wang, Aimin Chen.
       BACKGROUND: The incidence of nerve entrapment-related diseases, caused by a variety of factors, has been increasing annually, significantly impairing patients' quality of life. Nerve decompression serves as one of the critical approaches for treating such conditions. However, there remains a scarcity of bibliometric analyses within the field of nerve decompression.
    METHODS: The publications related to nerve decompression in the Web of Science (WoS) database from 2005 to 2024 were collected. Bibliometric methods were used to analyze the basic components of publications, synthesize research trends, and predict future research hotspots.
    RESULTS: A total of 606 publications were included in our study, with the number of publications ranging from 16 in 2005 to 52 in 2024. In terms of countries, the United States occupies a central position in both the number of publications (213 publications) and the quality (H-index = 34) and works closely with other countries. In terms of publishing institutions, Shanghai Jiao Tong University has the largest number of 18 publications. Acta Neurochirurgica is the journal with the highest number of 27 publications. The focus of research in this field can be divided into three main categories: cranial nerves, upper limb nerves, and lower limb nerves. The topic of research has gradually transferred to the lower limb nerve, and the keyword sacral nerve will be a hot topic in this field.
    CONCLUSION: This is the first bibliometric study to comprehensively summarize trends and hotspots in nerve decompression research. Our findings shed light on future research directions, international collaborations, and interdisciplinary relationships. The sacral nerve has emerged as a current and potential future research hotspot, warranting further exploration.
    Keywords:  bibliometric analysis; hotspots; nerve decompression; sacral nerve
    DOI:  https://doi.org/10.1016/j.wneu.2025.123968
  21. Nurse Educ Today. 2025 Apr 08. pii: S0260-6917(25)00176-5. [Epub ahead of print]151 106740
    Online learning in nursing education: A 21st century bibliometric analysis.
    Jennie C De Gagne, Paige S Randall, Paula D Koppel, Eunji Cho, Elizabeth R Blackwood, Hee Sun Kang.
       BACKGROUND: Online learning has become an integral part of nursing education, especially in response to the growing reliance on technology and the global transition to remote learning.
    AIM: This study explored research outputs and impact, collaborative networks, and thematic trends in online learning within nursing education to guide future educational advancements.
    METHODS: A bibliometric analysis was conducted using the Web of Science database to examine publications spanning from 2000 to August 2024. VOSviewer and Biblioshiny were utilized to assess publication trends, co-authorship, co-citation, and keyword co-occurrence, providing a comprehensive view of the research landscape. Descriptive statistics and visualizations were employed to enhance clarity and facilitate interpretation of key findings.
    RESULTS: The dataset encompassed 703 institutions across 56 countries, demonstrating the global scope of online learning research in nursing education. Publication output grew steadily, reaching a peak of 111 articles in 2022 (17 % of the total). The United States led with 555 publications and 2669 citations, followed by Australia (n = 92), Canada (n = 62), and Iran (n = 45). Co-authorship analysis revealed dense regional networks, with the University System of Ohio and the University of North Carolina as central hubs, though international collaborations were sparse. Keyword co-occurrence analysis identified three primary thematic clusters: (1) the impact of the COVID-19 pandemic, (2) student engagement, readiness, and motivation, and (3) technological integration and pedagogical approaches.
    CONCLUSIONS: This bibliometric analysis provides a comprehensive overview of online learning research in nursing education, highlighting its growth, thematic focus areas, and collaborative networks. The findings serve as a foundation for advancing evidence-based, inclusive, and innovative educational practices. Online learning is no longer a peripheral aspect of nursing education but a cornerstone for driving excellence, equity, and innovation. By addressing existing gaps and embracing emerging opportunities, stakeholders can reimagine nursing education to better prepare students for the challenges of modern healthcare.
    Keywords:  Bibliometric analysis; Educational innovations; Nursing education; Online learning
    DOI:  https://doi.org/10.1016/j.nedt.2025.106740
  22. J Thorac Dis. 2025 Mar 31. 17(3): 1228-1248
    Emerging trends and hotspots in chronic obstructive pulmonary disease and oxidative stress: a bibliometric and visualized analysis from 2010 to 2024.
    Rui Wang, Shujie Feng, Jiajie Jiang, Yonglong Chang, Yanping Zong, Jinchen Guo.
       Background: Chronic obstructive pulmonary disease (COPD) is a long-term respiratory condition defined by ongoing respiratory symptoms and restricted airflow, resulting in high rates of morbidity, mortality, and disability for this condition. Due to the incomplete understanding of its pathogenesis, no permanent curative measures or specific drugs are available. In recent years, a multitude of research has highlighted the substantial influence of oxidative stress on the development of COPD; however, there has been a deficiency in bibliometric analyses focusing on research trends and hotspots in the field. Therefore, our study aimed at presenting the emerging trends and hotspots related to COPD and oxidative stress.
    Methods: Publications concerning oxidative stress in COPD were obtained from the Web of Science Core Collection database, covering the period from 2010 to 2024. On July 25, 2024, all relevant data were downloaded, followed by a process of data screening and analysis.
    Results: The analysis incorporated 1,308 articles and 440 reviews, involving contributions from 1,034 researchers affiliated with 512 institutions across 64 countries published in a total of 548 journals. Through a series of analyses using five visualization tools, we identified the top 5 most productive countries, institutions, journals, and highly co-cited journals in the field from 2010 to 2024. We also identified 12 citation clusters, 10 influential authors, co-cited authors and articles, and 11 keyword clusters, established the top 20 keywords, and observed the evolution of reference and keyword bursts.
    Conclusions: This study is the first to quantitatively capture the progress of oxidative stress in the field of COPD research, and the results show a marked upward trend in recent years in terms of research on COPD and oxidative stress. Developing novel effective antioxidants is becoming the future direction for COPD treatment. Besides antioxidant therapy, exposure (to air pollution), cigarette smoke, and mitochondrial dysfunction emerged as prominent research hotspots. This extensive bibliometric study offers significant insights into the exploration of oxidative stress in publications related to COPD with the purpose to support and enhance future scientific research for investigators in the field.
    Keywords:  CiteSpace; Oxidative stress; VOSviewer; bibliometric analysis; chronic obstructive pulmonary disease (COPD)
    DOI:  https://doi.org/10.21037/jtd-24-1679
  23. Behav Neurol. 2025 ;2025 7106629
    Insomnia Comorbid With Depression: A Bibliometric and Visualized Analysis of Research Trends and Hotspots From 2000 to 2024.
    Junting Chen, Cai Li, Ling Chen, Ziyi Zhao, Yongsu Zheng, Xiaoyan Yang, Hao Huang, Renli Deng.
      Background: Sleep disorders, such as insomnia, are pervasive and frequently comorbid with depression, significantly affecting the quality of life of patients. Insomnia is characterized by difficulty initiating or maintaining sleep, which leads to impairment. Depression is characterized by persistent sadness and loss of interest, and it often features symptoms of insomnia. Understanding their interaction will be done for treatment strategies concerning both disorders. Despite the existence of extensive studies on insomnia and depression, there is a significant gap in bibliometric analysis specifically addressing the comorbidity of these two conditions. Objectives: This study is aimed at conducting a bibliometric analysis of research in insomnia comorbid with depression (ICD) to identify research trends, collaboration patterns, influential works, and hotspots. Methods: The study involved performance analysis to evaluate research productivity and trends, science mapping to visualize the intellectual structure and thematic evolution of the field, and network analysis to examine research collaboration and knowledge structure. Tools such as VOSviewer, CiteSpace, and GraphPad Prism were utilized for data analysis. Results: A total of 1624 publications on the comorbidity of insomnia and depression from 2000 to 2024 were included, encompassing both articles and reviews. Publication volume showed a steady growth from 2000 to 2008, followed by a significant increase from 2019 onward. The United States was the most productive country, followed by China. Key authors such as Allison G. Harvey, Charles M. Morin, and Daniel J. Buysse have made substantial contributions to the field. Major influential journals included Sleep Medicine, Journal of Affective Disorders, and Frontiers in Psychiatry. Research trends identified included the exploration of neurobiological mechanisms, cognitive behavioral therapy for insomnia (CBT-i), and personalized treatment approaches. Conclusion: This bibliometric analysis provides valuable insights into the evolving landscape of research on ICD. Future research should focus on personalized, multimodal interventions, expanding the application of CBT-i, exploring neurobiological mechanisms, and improving patients' quality of life through integrated treatment strategies.
    Keywords:  bibliometric analysis; comorbidity; depression; insomnia; visualization
    DOI:  https://doi.org/10.1155/bn/7106629
  24. J Nurs Manag. 2024 ;2024 8667809
    Trends and Hotspots in Nursing Theory Research Published from 1990 to 2022: A Web of Science-Based Bibliometric Analysis.
    Ruifang Zhu, Qian Wang, Jun Zhang, Weiliang Liu, Caizhen Ma, Shifan Han, Zhiguang Duan.
       Methods: This study adopted bibliometric approaches and analyzed the nursing theory research literature included in the Web of Science database during the 33 years between 1990 and 2022 using VOSviewer software. The source countries and regions, subject categories and distributions of institutions/units, journals, and highly productive authors of 23,180 nursing theory publications from the past 33 years were analyzed. The top ten funding agencies of nursing theory literature were also analyzed. Cluster and topic evolution analyses were performed on high-frequency keywords in nursing theory literature.
    Results: Historical trends in nursing theory were explored based on the number of articles published each year. The authoritative academic journals of nursing theory were identified based on the number of articles published, and the leaders of nursing theory and their academic research teams were identified based on the authors and their institutions. Moreover, the research hotspots and development trends in nursing theory were explored based on keyword clustering and topic evolution analysis. Thus, it is helpful to guide nursing practice and effectively solve nursing problems in nursing management.
    Conclusion: Research on nursing theory has been increasingly applied in clinical practice and tested or verified through clinical interventions in treating diseases. Theoretical research is inseparable from the development of nursing education. Moreover, research methods should be specific and diverse. Further improvement of theories depends on patient-centered clinical practice. Therefore, this study plays an important role in the continuous enrichment and development of nursing theory, which is conducive to further promoting the progress of nursing management and nursing discipline.
    DOI:  https://doi.org/10.1155/2024/8667809
  25. J Robot Surg. 2025 Apr 15. 19(1): 159
    A bibliometric analysis of augmented reality and mixed reality applied in minimally invasive surgery.
    Zhenxin Cai, Yina Zhou, Zheyu Wen, Luhao Li, Yuexiong Yi.
      Minimally invasive surgery (MIS) is integral to modern surgical practices, offering several advantages over traditional open surgery. The emergence of augmented reality (AR) and mixed reality (MR) technologies notably improved the surgical accuracy and safety of MIS. This study aims to conduct a comprehensive bibliometric analysis of AR and MR applications in MIS, identifying key trends and assessing the overall impact of these technologies on surgical practices. We systematically searched the WoSCC, PubMed, Scopus, and Embase for literature published between January 1, 1982, and August 14, 2024, using the keywords AR, MR and MIS. The search identified 5162 publications, of which 310 papers and reviews met the screening criteria. Bibliometric techniques were employed to analyze publication trends, country/region and institution participation, authorship, journal distribution, citation patterns and research hotspots. The annual publication rate has shown a steady upward trend since 2006, peaking at 50 publications in 2022. The United States, China and Germany were the leading countries. Top institutions included Johns Hopkins University and Imperial College London. The International Journal of Computer Assisted Radiology and Surgery had the highest publication count, while Surgical Endoscopy and Other Interventional Techniques received the most citations. Key research hotspots focused on spinal and liver surgeries, particularly in computer-assisted surgery and image-guided techniques, with advancements in integrating AR and MR with robotic systems, 3D printing, and machine learning. AR and MR technologies are increasingly used in MIS, especially in the enhancement of surgical navigation systems. This study provides insights for future research directions and practical applications in MIS.
    Keywords:  Augmented reality; Bibliometric study; Minimally invasive surgery; Mixed reality
    DOI:  https://doi.org/10.1007/s11701-025-02312-6
  26. Front Oncol. 2025 ;15 1490570
    Combining with immunotherapy is an emerging trend for local treatment of colorectal cancer liver metastases: a bibliometric analysis.
    Bin Shao, Ya-Shi Yin, Yi-Nuo Wei, Peng Dong, Hou-Fa Ning, Guang-Zhi Wang.
       Background: A growing body of evidence has demonstrated the expanding role of local treatment in managing colorectal cancer liver metastases (CRCLM). To identify current research trends and forecast future directions, we conducted a bibliometric analysis to examine global collaboration patterns and academic influence across countries, institutions, journals, and authors.
    Materials and methods: Relevant articles and reviews on CRCLM local therapies were systematically retrieved from the Web of Science Core Collection. The bibliometric package in R software and VOSviewer software were used to analyze countries, institutions, journals, authors, and keywords. The research status and key areas of local treatment of colorectal cancer liver metastases were analyzed by keywords.
    Results: The analysis encompassed 2,695 articles published between 2008 and 2023. The United States emerged as the leading contributor, with Memorial Sloan Kettering Cancer Center producing the highest number of publications (n=178). Among journals, Annals of Surgical Oncology ranked first in publication volume, while Journal of Vascular and Interventional Radiology achieved the highest citation count. The local treatment modalities for CRCLM included transarterial therapies (radioembolization and chemoembolization), hepatic artery infusion chemotherapy and immunotherapy, imaging guidance methods, hepatectomy and survival, and ablation and stereotactic body radiotherapy. Recent studies highlighted ablations, microspheres, and immunotherapy as key research areas, with thematic mapping identifying immunotherapy as an emerging niche field.
    Conclusion: CRCLM local treatment research focuses on integrating local and systemic therapies. Preclinical studies, RFA with anti - PD - 1 agents, show enhanced anti - tumor immunity and survival. While the synergy of local and immunotherapy is confirmed, large - scale clinical evidence is still needed. Thus, cross - disciplinary cooperation is urgently required to boost translational medical research.
    Keywords:  ablation; bibliometric analysis; colorectal cancer; immunotherapy; liver metastasis; local treatment; radiation therapy; transarterial chemoembolization
    DOI:  https://doi.org/10.3389/fonc.2025.1490570
  27. Front Oncol. 2025 ;15 1526610
    Neoadjuvant therapy for colorectal cancer from 2015 to 2024: a visual analysis and bibliometric analysis.
    Boyu Kang, Yihuan Qiao, Jun Zhu, Jipeng Li.
       Background: Colorectal cancer (CRC) imposes a substantial burden on global health., but research trends and hotspots in this field are still not clear. The purpose of this research is to create a visual knowledge map based on bibliometric analysis, identify research hotspots and predict future research trends.
    Method: Utilizing the Web of Science Core Collection (WoSCC) as data source and integrating the visualization capabilities of the Bibliometrix R software package, CiteSpace, and VOSviewer, analyze the authors, research institutions, countries, cited documents, publishing journals, abstracts, and keyword information of literature pertaining to neoadjuvant therapy for colorectal cancer spanning from January 2015 to December 2024.
    Result: The analysis included 1,587 articles from 1,464 institutions, 385 journals, and 61 countries or regions. China has the largest number of publications (449) and the largest number of citations (5,035). The United States occupies the leading position with an average of 21.6. "Annals of Surgical Oncology" is the most published journal with 51 articles, and "Journal of Clinical Oncology" is the journal with the most references (4,465 references). Highly cited references focus on clinical trials and guidelines for neoadjuvant therapy for colorectal cancer. In recent years, the most important keywords in the research on colorectal cancer and neoadjuvant therapy have been "artificial intelligence", "total neoadjuvant therapy" and "immunotherapy".
    Conclusion: This article provided a review of the research on neoadjuvant therapy for colorectal cancer, can provide reference for subsequent research on neoadjuvant therapy for colorectal cancer. The results offered valuable insights and data that informed the direction of future advancements.
    Keywords:  Bibliometrix; CiteSpace; VOSviewer; colorectal cancer; neoadjuvant therapy
    DOI:  https://doi.org/10.3389/fonc.2025.1526610
  28. Front Med (Lausanne). 2025 ;12 1573112
    Bibliometric analysis of multimodal analgesia research in the perioperative period: trends, contributions, and emerging areas (2013-2023).
    Wenchen Jiang, Yi Qin, Liang Chen.
       Objectives: Multimodal analgesia (MA) is a cornerstone in perioperative pain management, enhancing pain relief and minimizing opioid consumption by targeting various pain pathways. This study conducts a bibliometric analysis of MA research from 2013 to 2023 to understand its development and impact on perioperative care.
    Methods: A comprehensive literature search of the Web of Science Core Collection (WOSCC) was conducted, covering publications from January 2013 to December 2023. Data were analyzed using VOSviewer and other bibliometric tools to identify publication trends, key contributors, and emerging research themes.
    Results: The analysis identified 1,939 studies on MA, with a notable increase in annual publications since 2020. The USA, China, and Canada were the leading contributors. Key terms like Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Enhanced Recovery After Surgery (ERAS), and Patient-Controlled Analgesia (PCA) were frequently associated with MA. Significant journals included the Cureus Journal of Medical Science and Anesthesia and Analgesia. Influential authors such as Richard D. Urman and Henrik Kehlet were highlighted for their contributions. The research showed significant advancements and growing global interest in MA.
    Conclusion: The study underscores the growing importance of MA in perioperative pain management, with significant contributions from leading countries and researchers. Future research should focus on optimizing pain management protocols, enhancing patient recovery, and reducing opioid dependency through MA.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; multimodal analgesia; perioperative pain management
    DOI:  https://doi.org/10.3389/fmed.2025.1573112
  29. Surg Endosc. 2025 Apr 14.
    Global trends and insights of telesurgery research: a bibliometric analysis of publications since the 21st century.
    Guangdi Chu, Bo Guan, Xiaoyu Ji, Xue Yu, Ruonan Yang, Sevval Besli, Jianchang Zhao, Yuan Gao, Jianning Wang, Shuxin Wang, Jianmin Li, Haitao Niu.
       BACKGROUND: In recent years, telesurgery has shown a rapid development trend as an innovative surgical technique, and been applied to the clinical treatment of various tumor diseases. However, the current research on telesurgery is still relatively fragmented, lacking a systematic summary of its development and future directions. Addressing these limitations is crucial for advancing the application of this novel surgical technology.
    METHODS: This bibliometric study of publications related to telesurgery that were indexed in the Web of Science Core Collection from 2000 to 2024. VOSviewer, CiteSpace, and Bibliometrix were used to analyze and visually represent the gathered data, and the relevant content was presented according to the BIBLIO guidelines.
    RESULTS: We researched 565 publications across 269 journals authored by 2422 individuals affiliated with 917 institutions spanning 62 countries. Notably, the United States leads in the number of publications, with China also making noteworthy contributions. Kyushu University and the University of Washington emerge as prominent institutions in terms of research output within this domain. Analysis of document co-occurrence and co-citation reveals that Jacques Marescaux from France holds the top position globally among authors and wields significant influence in this field. Keyword analysis indicates that key future research directions in this area include mitigating latency issues in telesurgery, integrating advanced network communication technologies, and enhancing the performance of telesurgical robots. Furthermore, ethical and legal issues associated with telesurgery may emerge as critical challenges to be addressed for its further expansion and application.
    CONCLUSION: This research provides an overview of telesurgery research findings, encompassing the evolution of research priorities in telesurgery. The study anticipates that the secure implementation and broader adoption of telesurgery will bring more benefits to patients on a global scale.
    Keywords:  Bibliometric analysis; Research trends; Telemedicine; Telesurgery
    DOI:  https://doi.org/10.1007/s00464-025-11697-2
  30. Front Pharmacol. 2025 ;16 1570238
    Inflammatory bowel disease therapeutics: a bibliometric analysis of tofacitinib research in ulcerative colitis.
    Jianping Zhou, Yuting Xi, Yaping Zhang, Rui Zhang, Hao Fu, Ce Zhou.
       Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease affecting millions worldwide. Tofacitinib, an inhibitor of Janus kinase (JAK), has shown considerable potential as an effective treatment option for individuals suffering from moderate to severe UC, aiming to mitigate the risk of colectomy, hospitalization, and disease exacerbation.
    Methods: We conducted a comprehensive literature review from 2012 to 2024 to assess the study landscape of Tofacitinib in UC. Employing the Web of Science Core Collection database (WOSCC) and the bibliometric tool CiteSpace, we performed an bibliometric analysis to delineate disciplinary evolution and identify research hotspots within the UC Tofacitinib domain.
    Results: Our analysis extracted 406 UC Tofacitinib-related articles from WOSCC, indicating a growing body of literature. The United States and Europe are at the forefront of research maturity, with a significant contribution to the field. Here we show that multidisciplinary research is burgeoning, which is crucial for the advancement of UC Tofacitinib studies. We identified 13 highly cited documents and 10 co-cited documents, highlighting Tofacitinib's prominence as a small molecule agent. Keyword analysis revealed that the intestinal barrier, clinical response, remission rate, and safety are the central themes of current research.
    Conclusion: By applying bibliometrics, citation analysis, and knowledge mapping, this study provides a snapshot of the current state and trajectory of Tofacitinib research in UC. We have elucidated the knowledge lineage in this field, offering insights that can inform both ongoing and future research endeavors. Our findings underscore the importance of multidisciplinary collaboration in advancing UC therapeutic strategies.
    Keywords:  adverse event; bibliometric analysis; clinical response; remission; tofacitinib; ulcerative colitis
    DOI:  https://doi.org/10.3389/fphar.2025.1570238
  31. Front Pharmacol. 2025 ;16 1562765
    Global research frontiers and thematic trends in opioid-free anesthesia over the past 20 years: a bibliometric analysis.
    Junchen He, Rong Huang, Yingzhu Liu, Ying Chen, Min Zhong.
       Objective: Opioids have constituted an essential element of general anesthesia for a considerable length of time. However, with the increase in opioid misuse and associated postoperative adverse effects, studies related to opioid-free anesthesia (OFA) have emerged, which pose a challenge in identifying key research directions. Accordingly, the objective of this study was to provide a review of the relevant literature in the field of OFA over the past 2 decades, with the goal of identifying the prevailing trends and research Frontiers.
    Methods: A systematic review of the publications on OFA was conducted using the Web of Science Core Collection database, with the objective of identifying relevant publications between the years 2005 and 2024. The bibliometric analysis was conducted using CiteSpace (version 6.1. R6), VOSviewer (version 1.6.19), and R (version4.4.2).
    Results: In conclusion, 477 publications were included in this study. The number of annual publications in this field has exhibited a steady increase over the past 2 decades. The United States and its institutions were found to be the most central. Forget, Patrice, and BELOEIL H were identified as the most prolific and highly cited authors, respectively. The journal with the highest number of publications was BMC Anesthesiology. The most frequently cited journal was Anesthesia and Analgesia, followed by Anesthesiology. In addition, keyword burst, keywords co-occurrence, and analysis of cited references indicate that recent studies have focused on: opioid consumption, pain, and postoperative nausea and vomiting (PONV). Meanwhile, analysis of keyword clusters and keywords timeline view showed that the main research frontiers are sevoflurane anesthesia, plane block, multimodal anesthesia, opioid-sparing anesthesia.
    Conclusion: Our results show that the current trends and directions of research focus on opioid consumption, pain, and PONV. Frontiers for future research are expected to include research areas related to sevoflurane anesthesia, plane block, multimodal anesthesia, opioid-sparing anesthesia.
    Keywords:  bibliometric analysis; citespace; multimodal analgesia; opioid-free anesthesia; plane block; postoperative nausea and vomiting
    DOI:  https://doi.org/10.3389/fphar.2025.1562765
  32. Front Nutr. 2025 ;12 1528366
    Global research trends in obesity-related asthma (2004-2023): a bibliometric analysis.
    Liye Lang, Mingxuan Ma, Hui Zhao, Jialin Zhang, Sheng Liu, Hua Liu.
       Background: In recent years, an increasing body of evidence has revealed a complex interplay between obesity and asthma, prompting academic and medical communities to intensify their focus on this area of research. The objective of this study is to undertake a comprehensive bibliometric analysis of the research literature pertaining to obesity-related asthma from 2004 to 2023. This analysis aims to provide precise and valuable insights, as well as to systematically reflect upon the current status and emerging trends within the field.
    Methods: Literature data on obesity and asthma research was sourced from the Web of Science Core Collection database. CiteSpace and VOSviewer were utilized to visually analyze bibliometric indicators such as co-authorship, citation networks, and publication frequency of the data to facilitate the identification of patterns and trends.
    Results: A total of 3,118 papers were included in the analysis, encompassing 2,539 articles and 579 reviews. Throughout the last 20 years, the volume of publications has shown a consistent upward trend. The United States and Harvard University are at the forefront of this research field. Professor Dixon Anne E. is recognized as a pioneer and leading figure in the cultivation of obesity-related asthma research. Keyword analysis identified topics such as "childhood asthma," "bariatric surgery," "physical activity," "gut microbiota," "COVID-19," "food allergy," "asthma control," "nutrition examination," and "severe asthma."
    Conclusion: The research domain of obesity-related asthma has experienced a substantial growth, with the United States, the United Kingdom, and China leading the global landscape. The focus on asthma in obese adolescents and children, the role of bariatric surgery, and lifestyle interventions remains a consistent area of interest, with considerable potential for further study. These findings provide a scientific basis for the development of personalized treatment programs for obese asthma patients. In addition, this study highlights the importance of further research in the fields of gut microbiota, COVID-19, and food allergy, providing directions for future policymaking.
    Keywords:  asthma; bibliometrics; hotspots; obesity; visualization
    DOI:  https://doi.org/10.3389/fnut.2025.1528366
  33. Discov Oncol. 2025 Apr 16. 16(1): 537
    Artificial intelligence-assisted multimodal imaging for the clinical applications of breast cancer: a bibliometric analysis.
    Chenke Hou, Ting Huang, Keke Hu, Zhifeng Ye, Junhua Guo, Heran Zhou.
       BACKGROUND: Breast cancer (BC) remains a leading cause of cancer-related mortality among women globally, with increasing incidence rates posing significant public health challenges. Recent advancements in artificial intelligence (AI) have revolutionized medical imaging, particularly in enhancing diagnostic accuracy and prognostic capabilities for BC. While multimodal imaging combined with AI has shown remarkable potential, a comprehensive analysis is needed to synthesize current research and identify emerging trends and hotspots in AI-assisted multimodal imaging for BC.
    METHODS: This study analyzed literature on AI-assisted multimodal imaging in BC from January 2010 to November 2024 in Web of Science Core Collection (WoSCC). Bibliometric and visualization tools, including VOSviewer, CiteSpace, and the Bibliometrix R package, were employed to assess countries, institutions, authors, journals, and keywords.
    RESULTS: A total of 80 publications were included, revealing a steady increase in annual publications and citations, with a notable surge post-2021. China led in productivity and citations, while Germany exhibited the highest citation average. The United States demonstrated the strongest international collaboration. The most productive institution and author are Radboud University Nijmegen and Xi, Xiaoming. Publications were predominantly published in Computerized Medical Imaging and Graphics, with Qian, XJ's 2021 study on BC risk prediction under deep learning frameworks being the most influential. Keyword analysis highlighted themes such as "breast cancer", "classification", and "deep learning".
    CONCLUSIONS: AI-assisted multimodal imaging has significantly advanced BC diagnosis and management, with promising future developments. This study offers researchers a comprehensive overview of current frameworks and emerging research directions. Future efforts are expected to focus on improving diagnostic precision and refining therapeutic strategies through optimized imaging techniques and AI algorithms, emphasizing international collaboration to drive innovation and clinical translation.
    Keywords:  Artificial intelligence; Bibliometric analysis; Breast cancer; Multimodal imaging
    DOI:  https://doi.org/10.1007/s12672-025-02329-1
  34. Oral Surg Oral Med Oral Pathol Oral Radiol. 2025 Mar 07. pii: S2212-4403(25)00826-0. [Epub ahead of print]
    A bibliometric analysis of the current status of salivary gland tumors.
    Zhou Zhongwei, Li Yunlong, Wang Yanan, Zhou Qi, Mao Jingjing, Chen Yaoqi, He Qiao, Li Kelong.
       OBJECTIVE: Salivary gland tumors have been extensively studied; however, a comprehensive and systematic bibliometric analysis is still lacking. This study aims to summarize the progress in salivary gland tumor research through bibliometric analysis.
    RESEARCH METHODS: A total of 1,223 articles and reviews were retrieved from the Web of Science Core Collection (WoSCC). Excel 2019 and CiteSpace software were used to visually analyze research trends, authors, journals, institutions, countries, keywords, and cited references.
    RESULTS: Emerging research topics include the etiology of salivary gland tumors, the effects of head and neck radiation therapy, and adenoid cystic carcinoma (ACC), suggesting potential future research directions. The relationship between tumor incidence and postoperative recurrence remains controversial, underscoring the need for standardized terminology, updated classifications, and robust evidence-based studies to clarify these connections.
    CONCLUSION: Explosive keywords and hotspot literature indicate that the etiology of salivary gland tumors, the impact of radiotherapy on salivary glands in head and neck tumors, and adenoid cystic carcinoma (ACC) are key research areas in the current and future landscape.
    DOI:  https://doi.org/10.1016/j.oooo.2025.03.002
  35. Front Oncol. 2025 ;15 1522992
    Hotspots and scientometrics in gallbladder cancer surgery research: a bibliometric and visualization analysis (2014-2024).
    Long-Fei Chen, Jian-Feng Bin, Qin Zhang, Han Li, Wei Chen, Hua Ge.
       Background: Gallbladder cancer (GBC) is the most common malignancy of the biliary tract, with significant geographical variations in incidence. The prognosis of GBC is generally poor due to its aggressive nature and late diagnosis. Surgical resection is the only curative treatment, but less than 10% of patients are eligible for radical surgery.
    Methods: This study utilized bibliometric analysis and visualization tools to analyze research trends and hotspots in GBC surgery from 2014 to 2024. Data were collected from the Web of Science Core Collection using specific search terms related to GBC and surgical methods. The analysis was performed using tools such as CiteSpace, VOSviewer, and Microsoft Excel to identify key authors, institutions, countries, and research themes.
    Results: A total of 479 publications were analyzed, showing a significant increase in research output and citation frequency over the past decade. China and the United States were the leading contributors to GBC surgery research. The analysis revealed six main research clusters, focusing on early diagnosis, surgical techniques, postoperative management, and the application of advanced technologies such as laparoscopic and robotic surgery.
    Conclusions: The study highlights the evolution of research priorities in GBC surgery, with a shift towards minimally invasive techniques and comprehensive postoperative management. Future research should emphasize international collaboration and the exploration of emerging technologies to improve patient outcomes.
    Keywords:  bibliometric analysis; gallbladder cancer; laparoscopic surgery; postoperative management; surgery
    DOI:  https://doi.org/10.3389/fonc.2025.1522992
  36. Front Immunol. 2025 ;16 1514831
    Pulmonary fibrosis complicated by lung cancer: bibliometric analysis from 2004 to 2024 - research status, trends and future directions.
    Boyang Li, Fan Wu, Xinlai Ma, Weishan Yuan, Jiaqing Li, Wei Zhang, Xue Liu.
       Objective: Although research on the association between pulmonary fibrosis and lung cancer is of great significance, to date, no bibliometric analysis has been conducted on the comorbidity of these two diseases. This study aims to explore the current status and cutting - edge trends in this field through bibliometric analysis, and to establish new directions for future research.
    Methods: Using the Web of Science Core Collection database, statistical calculations, graphic, and data visualization tools such as CiteSpace, VOSviewer, and Biblimatrix - biblioshiny were adopted.
    Results: A total of 2,234 original Articles and Reviews on pulmonary fibrosis complicated by lung cancer published between 2004 and 2024 were identified. A slow growth trend in publications related to pulmonary fibrosis complicated by lung cancer was observed. The United States, Japan, and China were the countries with the greatest contributions. Professor Michael Kreuter from Marienhaus Clinic, Mainz, Germany, and the University of Michigan published the most articles. Through cluster analysis of co - cited literature, five main clusters were identified. Keyword analysis predicted that "nintedanib", "pirfenidone", "immunotherapy", etc. might become hot topics in the field of the comorbidity of pulmonary fibrosis and lung cancer.
    Conclusion: This bibliometric analysis shows that the literature related to the comorbidity of pulmonary fibrosis and lung cancer is on a continuous upward trend. The research hotspots and trends identified in this study provide a reference for in - depth research in this field, aiming to promote the development of research on the comorbidity of pulmonary fibrosis and lung cancer.
    Keywords:  bibliometrics; immunotherapy; lung cancer; nintedanib; pirfenidone; pulmonary fibrosis
    DOI:  https://doi.org/10.3389/fimmu.2025.1514831
  37. Front Surg. 2025 ;12 1550816
    Bibliometric study of research trends in dysphagia complicating following anterior cervical spine surgery.
    Shang Qisong, Xiang Wei, Wu Yuanyuan, Song Xinghua.
       Background: The aim of this study was to assess the global research status and trends in the occurrence of dysphagia after cervical spine surgery using bibliometrics.
    Methods: All relevant research publications on dysphagia occurring after cervical spine surgery were retrieved from the Web of Science Core Collection database. Literature coupling, co-citation and co-occurrence analyses were subsequently visualised using VOSviewer, CiteSpace. WPS Office was applied for data summary processing.
    Results: Between 2000 and 2023, a total of 477 clinical studies met the inclusion criteria. The number of global publications has steadily increased in four stages over the last 19 years, with the United States having the most publications (=194), followed by China (=134) and South Korea (=34). The most contributing institutions were UNIVERSITY OF CALIFORNIA SYSTEM in the USA (n = 24) and SICHUAN UNIVERSITY in China (n-21). The most distinguished scholar was Liu,Hao (n = 15), followed by Albert (n = 10) and Yang,Yi (n = 9). Ten of the most cited papers were cited more than 65 times. The most important journal for research on the occurrence of dysphagia after cervical spine surgery was SPNIE (n = 445), followed by EUR SPINE J (n = 337) and SPINE J (n = 322), which analysed a number of factors including anatomy, patient information and the use of inbuilt objects. The top 20 most commonly used keywords were identified from 750 author keywords, with the highest number being dysphagia (n = 303), followed by fusion (n = 183) and spine surgery (182). In parallel with time zone and cluster analysis we found multiple high frequency keywords that appeared as early as 2006 and have continued to the present day, reflecting the enthusiasm of a large number of scholars who have researched this topic.
    Conclusion: This bibliometric study analyses the global research hotspots and trends in postoperative cervical spine complication dysphagia in terms of study type, patient information, surgical modality, surgical segment, most popular keywords, most cited papers, journals, authors, institutions, and countries, to guide future practice and direction, in order to help understand how to effectively prevent or reduce the incidence of this postoperative complication so as to achieve the goal of lowering the patient's healthcare costs, to balance social medical resources and reduce the financial burden of the government.
    Keywords:  CiteSpace; VOSviewers; anterior cervical spine surgery; bibliometrics; dysphagia
    DOI:  https://doi.org/10.3389/fsurg.2025.1550816
  38. Transl Androl Urol. 2025 Mar 30. 14(3): 553-566
    From obesity to inflammation: emerging frontiers in prostate cancer and metabolic syndrome studies.
    Xi Xu, Jinshan Xu, Hongliang Gao, Zhaoyang Sheng, Yang Xu, Shuxiong Zeng, Guanghua Chen, Zhensheng Zhang.
       Background: According to recent studies, prostate cancer (PCa) is strongly associated with metabolic syndrome (MetS). However, there has not been any bibliometric visual analysis of relevant papers. In order to acquire knowledge about research settings and possible future paths, a thorough bibliometric study of MetS-related PCa research was carried out.
    Methods: From January 1, 2004 to December 31, 2023, original and review publications about MetS and PCa were retrieved from the Web of Science Core Collection (WOSCC) database. Analysis of co-authorship and co-occurrence was done using VOSviewer. To find the top terms with the greatest citation burst, CiteSpace was used.
    Results: There were 1,296 publications on PCa and MetS in all. The analysis showed that the number of yearly scientific papers in the sector was on the rise. The three most productive nations were China, Italy, and the USA. Most papers were published in the PLoS One, while most citations were obtained by the European Urology. The most influential author in terms of citations was Professor Smith MR, whereas the most prolific author was Professor Freedland SJ. Keyword analysis revealed that, apart from PCa and MetS, "obesity" was the most often used phrase, with "risk", "meta-analysis", and "inflammation" appearing as study subjects. Furthermore, "components" and "sex hormones" gained more and more attention.
    Conclusions: The findings provide a thorough understanding of the larger context of this field of study. Future studies need to investigate PCa's metabolic processes and inflammatory mechanism. Furthermore, switching from observational research to meta-analysis offers the possibility of illness prediction and tailored therapies. These results may help researchers navigate the most recent advancements and influence the field's future paths.
    Keywords:  Prostate cancer (PCa); bibliometric; inflammation; metabolic syndrome (MetS); obesity
    DOI:  https://doi.org/10.21037/tau-2024-671
  39. Front Plant Sci. 2025 ;16 1400159
    Study on the potential capacity of cake fertilizer agricultural solid emission reduction and soil improvement based on CiteSpace.
    Yuliang Fu, Gang Li, Songlin Wang, Zhiguang Dai, Xiaoyuan Zhang.
       Introduction: The goal was to gain a comprehensive understanding of the current research status, hotspots and cutting-edge dynamics in the field of cake fertilizer application in agriculture at home and abroad from 2000 to 2024.
    Methods: The study employed the bibliometric analysis method and CiteSpace visualisation software to investigate the research results of the field of cake fertilizer agriculture in greenhouse gases and soil improvement included in the Core Collection Database of Web of Science.
    Results: The findings of the keyword analysis, collaborative network analysis, and publication count analysis demonstrated that (1) "The number of related literatures was small and in its infancy before 2007,accounting for 17% of the total number of publications; the slow growth phase was from 2008-2016, accounting for 39% of the total number of publications(with a growth rate of 1.65%); and the rapid increase phase was after 2017-2023, accounting for 39% of the total number of publications(with a growth rate of 3.89%). (2) India ranked first in terms of the number of publications, and China ranked second in terms of the number of publications, but China was first in terms of intermediary centrality, and the authors were all loosely distributed, choosing to publish their research results in international journals with an impact factor of greater than 2 in the field of agriculture. (3) Universities are the primary source of research findings in this field among the issuing institutions. (4) The research hotspots include nitrogen, soil, growth, yield, manure, fertilizer, quality, management; The research themes with the greatest number of keywords are "bag filiter," and "bacillus sp " has the highest profile value; The development trends are as follows: prior to 2016, the fertilizer program studied various organic fertilizers in combination with chemical fertilizers or different types of organic fertilizers to explore the impact on crop yields; subsequent to 2016, the fertilizer program studied cake fertilizers with new materials to evaluate the impact on crop yield quality and soil fertility. Going forward, the emphasis should be on blending environmentally friendly components with cake fertilizers and carrying out comprehensive studies on soil enhancement and greenhouse gas mitigation strategies.
    Discussion: This study offers new insights and ideas on the future research direction and development potential of cake fertilizer in agricultural greenhouse gas emission reduction and soil improvement. It also serves as a valuable reference for understanding the development trend of cake fertilizer application in agriculture from 2000 to 2023.
    Keywords:  CiteSpace; cake fertilizers; greenhouse gas; potential capacity; soil improvement
    DOI:  https://doi.org/10.3389/fpls.2025.1400159
  40. Front Pharmacol. 2025 ;16 1484437
    The status and hotspot analysis of research on extracellular vesicles and osteoarthritis: a bibliometric analysis.
    Wen Hao Zhang, Wen Yuan Xiang, Lin Yi, Rui Fang.
       Background: Degenerative joint disease, known as osteoarthritis (OA), is characterized by pain, swelling, and decreased mobility. The illness has a major negative influence on patients' quality of life and is common around the world, especially among older people. Nevertheless, there are insufficient possibilities for early diagnosis and therapy. Extracellular vesicles, or EVs, control the immune response, tissue healing, and cellular communication.
    Methods: This work offers a bibliometric representation of the areas of focus and correlations between extracellular vesicles and osteoarthritis. We searched for osteoarthritis and extracellular vesicles in publications in the Web of Science Core Collection (WoSCC) database. Bibliometrics, an R package, CiteSpace 6.1. R2, and VOSviewer 1.6.17 were used to perform bibliometric analyses of concentration fields, trends, and relevant factors.
    Results: 944 papers from 59 nations were published; the countries that contributed the most to the field were China, the USA, and Italy. Professors Laura and Enrico are the top contributors. Sichuan University, Istituto Ortopedico Galeazzi, and Shanghai Jiao Tong University are the top three universities. The International Journal of Molecular Sciences is an excellent publication. Exosome, expression, knee osteoarthritis, extracellular vesicle, mesenchymal stem cell, osteoarthritis, and inflammation are the most often occurring keywords.
    Conclusion: These results suggest areas of interest and focus for future research on EVs and OA. This trend suggests that the volume of literature on OA and EVs will continue to rise, with more research being published in the future. This study helps scholars understand current research hotspots in the field and may inspire future research.
    Keywords:  bibliometric; extracellular vesicles; hotspots; mesenchymal stem cell; osteoarthritis
    DOI:  https://doi.org/10.3389/fphar.2025.1484437
  41. Semin Ophthalmol. 2025 Apr 14. 1-13
    Emerging Insights in Thyroid Eye Disease Research from 2010 to 2022: Trends, Hot Spots, and Research Situation.
    Yu-Xuan Wan, Guo-Qing Li, Sai-Li Duan, Shi Chang.
       PURPOSE: Thyroid eye disease, the most frequent extra-thyroid manifestation of Graves' disease, has puzzled physicians and scientists and could potentially make patients sight-threatened. This study aimed to aid researchers and readers in this field to improve their understanding of thyroid eye disease research trends and provide ideas for future research from unique perspectives.
    METHODS: The top 100 most-cited papers on Graves' ophthalmopathy from January 1, 2010, to December 31, 2022, were retrieved from the Web of Science Core Collection database. Two authors defined and analyzed these data independently via CiteSpace, Vosviewer, and Tableau.
    RESULTS: A total of 1861 publications linked with Graves' ophthalmopathy research were identified. All of these 100 top-cited papers were published between 2010 and 2022, and the United States of America (USA), Italy, Germany, England, Netherlands, and China made significant contributions to Graves' ophthalmopathy research. The journal with the highest number of published papers is the Journal of Clinical Endocrinology & Metabolism (n = 22). The USA was the most productive country in this topic (n = 29). The Johannes Gutenberg University of Mainz had the largest number of publications (n = 8) and citations (n = 1610). The most cited article was 'MECHANISMS OF DISEASE Graves' Ophthalmopathy'. The clustered network and timeline of keywords showed the prevalence, diagnosis, and treatment of thyroid eye disease, which were the research core themes during the past 12 years.
    CONCLUSIONS: This study provided insights into the most influential studies related to thyroid eye disease via analyzing the top 100 most-cited papers in thyroid eye disease research.
    Keywords:  Bibliometric study; Graves’ ophthalmology; hotspot; thyroid eye disease; trend
    DOI:  https://doi.org/10.1080/08820538.2025.2490669
  42. Carcinogenesis. 2025 Apr 17. pii: bgaf021. [Epub ahead of print]
    B vitamins and colorectal cancer: exploring research hotspots and frontiers from a bibliometric and visual analysis (1994-2024).
    Meichen Li, Lingshi Meng, Hong Gu, Yuan Tian, Boyang Qu, Yanrong Ao, Xingyang Chen, Yuan Song, Weiwei Cui.
      Most studies suggest that B vitamins can reduce the risk of colorectal cancer (CRC), and research in this field has been growing. Focusing on 2617 articles in the field, this study used CiteSpace and VOSviewer software to evaluate the contributions of various countries/regions, institutions, authors and journals. The United States and Harvard University were identified as the most productive nation and institution, respectively, with Edward L. Giovannucci (Harvard) being the top contributor. Cancer Epidemiology Biomarkers & Prevention was recognized as the leading journal. Through the analysis of keywords and citations, we found that the potential of B vitamins (B1, B2, B6, B9, and B12) in the prevention and treatment of CRC and their mechanisms including regulation of gene expression, anti-inflammatory and antioxidant, and modulation of gut microenvironment are hot topics of research in this field. Burst detection analysis further revealed that the application of nanoparticle-based targeted drug delivery systems (such as folate-conjugated nanocarriers) in the treatment of CRC represents both a current hotspot and a future trend. This study offers a comprehensive overview of the field, highlights research hotspots and trends, and offers valuable information for researchers to further grasp the research direction.
    Keywords:  B vitamins; bibliometric analysis; colorectal cancer; research frontiers; research hotspots
    DOI:  https://doi.org/10.1093/carcin/bgaf021
  43. Iran J Public Health. 2025 Feb;54(2): 346-360
    A Scientometric Perspective on Stigma Research in Medicine: A Bibliometric Review.
    Hossein Akbari, Mahla Mohammadi, Abolfazl Hosseini.
       Background: Stigma is a critical social determinant of health, influencing individuals' access to resources, quality of life, and overall well-being. Despite its significant implications, bibliometric studies on stigma in the medical field remain sparse. We provide a comprehensive scientometric analysis of stigma research in medicine over the past 30 years, highlighting trends, key focus areas, and evolving challenges.
    Methods: A bibliometric analysis was conducted using VOSviewer software, utilizing data from the Scopus database. The search included articles with the keyword "stigma*" in the title, published between 1992 and 2022, within the fields of Medicine, Nursing, and Professional Health. The initial search yielded 20,284 articles, narrowed down to 7,854 relevant publications for detailed analysis. Key metrics analyzed included co-authorship, co-occurrence of keywords, and co-citation patterns.
    Results: The analysis revealed a significant increase in stigma-related publications in the medical field, particularly since 2010, with a peak in 2022, largely driven by the COVID-19 pandemic. The research identified nine major keyword clusters, 40 associated diseases, and 36 target groups. Persistent diseases like HIV, mental illness, addiction, and cancer continue to be strongly associated with stigma.
    Conclusion: The findings underscore the evolving nature of stigma research in medicine, with an increasing focus on intersecting stigmas and their persistent impact on public health. Future research should aim to develop comprehensive models and strategies to manage and reduce stigma, particularly for diseases with enduring stigmatic associations. Collaborative efforts among policymakers, healthcare providers, and society are crucial to address the social and economic consequences of stigma and improve health outcomes.
    Keywords:  Bibliometric analysis; Stigma; VOSviewer
  44. Fundam Res. 2025 Mar;5(2): 437-449
    Supply chain resilience from the maritime transportation perspective: A bibliometric analysis and research directions.
    Dengyuhui Li, Jianbin Jiao, Shouyang Wang, Guanghui Zhou.
      Maritime transportation is responsible for the vast majority of global overseas commerce. However, systematic reviews of supply chain resilience from the maritime transportation perspective are limited. This study provides descriptive statistical analysis, bibliometric analysis, and literature review based on relevant papers from 2004 to 2022 to clarify developments in this field. Growth trends, research areas, research regions, influential journals, influential institutions, and highly cited articles are discussed in the statistical analysis. The bibliometric analysis includes collaboration networks, emerging trends, and co-citation analysis. Topical issues and methods in the field are discussed based on papers from 10 highlighted research clusters. Then, studies on resilience measurement, resilience evaluation, and resilience improvement in maritime transportation are reviewed and future directions are proposed. This study summarizes the emerging trends and developments of supply chain resilience from the maritime transportation perspective and supports the establishment of a more dependable maritime transportation system.
    Keywords:  Bibliometric analysis; Co-citation analysis; Maritime transportation; Supply chain disruption; Supply chain resilience
    DOI:  https://doi.org/10.1016/j.fmre.2023.04.003
  45. Healthcare (Basel). 2025 Mar 26. pii: 740. [Epub ahead of print]13(7):
    Insights into the Technological Evolution and Research Trends of Mobile Health: Bibliometric Analysis.
    Ruichen Zhang, Hongyun Wang.
      Background/Objectives: Smartphones, with their widespread popularity and diverse apps, have become essential in our daily lives, and ongoing advancements in information technology have unlocked their significant potential in healthcare. Our goal is to identify the future research directions of mobile health (mHealth) by examining its research trends and emerging hotspots. Methods: This study collected mHealth-related literature published between 2005 and 2024 from the Web of Science database. We conducted a descriptive statistic of the annual publication count and categorized the data by authors and institutions. In addition, we developed visualization maps to display the frequency of keyword co-occurrences. Furthermore, overlay visualizations were created to showcase the average publication year of specific keywords, helping to track the changing trends in mHealth research over time. Results: Between 2005 and 2024, a total of 6093 research papers related to mHealth were published. The data have revealed a rapid increase in the number of publications since 2011. However, it was found that research on mHealth has reached a saturation point since 2021. The University of California was the dominant force in mHealth research, with 248 articles. The University of California, the University of London, Harvard University, and Duke University are actively collaborating, which shows a geographical pattern of collaboration. From the analysis of keyword co-occurrence and timeline, the research focus has gradually shifted from solely mHealth technologies to exploring how new technologies, such as artificial intelligence (AI) in mobile apps, can actively intervene in patient conditions, including breast cancer, diabetes, and other chronic diseases. Privacy protection policies and transparency mechanisms have emerged as an active research focus in current mHealth development. Notably, cutting-edge technologies such as the Internet of Things (IoT), blockchain, and virtual reality (VR) are being increasingly integrated into mHealth systems. These technological convergences are likely to constitute key research priorities in the field, particularly in addressing security vulnerabilities while enhancing service scalability. Conclusions: Although the volume of core research in mobile health (mHealth) is gradually declining, its practical applications continue to expand across diverse domains, increasingly integrating with multiple emerging technologies. It is believed that mobile health still holds enormous potential.
    Keywords:  bibliometric analysis; data visualization; digital intervention; mHealth app; mental health; mobile health (mHealth)
    DOI:  https://doi.org/10.3390/healthcare13070740
  46. J Nurs Manag. 2025 ;2025 2169094
    Mental Health of Nursing Students: A Bibliometric Review Based on CiteSpace Visual Analysis.
    Hong Xie, Bingyao Kang.
      Background: The mental health of nursing students directly affects their future performance, quality of patient care, and personal development. Therefore, an in-depth understanding of research in this area can assist in implementing effective measures to improve the mental health of nursing students. Aim: This study used bibliometric analyses to identify and analyze articles, authors, journals, and research institutes investigating nursing students' mental health in terms of thematic structure and topic evolution, aiming to provide direction and guidance for future research. Methods: In this retrospective bibliometric analysis, data were downloaded from the Web of Science Core Collection on August 15, 2024. Subsequently, CiteSpace software was employed to analyze the annual number of publications and citations, explore relationships between authors, institutions, countries, and keywords, and summarize research hotspots and frontiers in the field of nursing students' mental health. Results: Articles published from database inception to August 15, 2024, were screened, leading to the retrieval of 3803 relevant articles. The United States of America was the leading country in terms of research output on the mental health of nursing students, with 982 (25.79%) published articles, while the United States Department of Health and Human Services provided the most funding. Furthermore, Happell, B was the most productive author in this field, with 80 published papers. Lastly, Nurse Education Today was the most prolific journal in nursing education. Conclusion: The main recent research trends include the psychological profile of nursing students, intervention strategies for improving the mental health of nursing students, and the influence of educational methods, clinical experience, and humanistic care on the mental health of nursing students. These trends imply that researchers should develop targeted training programs, apply information technology, and implement personalized teaching to enhance the psychological resilience of the nursing student population. Moreover, higher education institutions should provide nursing students with more comprehensive and effective mental health support by maintaining mental health files, strengthening mental health education, providing psychological counseling services, and establishing social support systems.
    Keywords:  bibliometric literature; mental health; nursing students; review
    DOI:  https://doi.org/10.1155/jonm/2169094
  47. Otolaryngol Head Neck Surg. 2025 Apr 18.
    Global Collaborative Trends in Otolaryngology Research: U.S. Partnerships With Low-, Middle-, and Other High-Income Countries.
    Shiven Sharma, Mohammed Abduljalil, Dany Alkurdi, Omar Alani, Vikram Vasan, Shreya Deshmukh, Prabhjot Singh, Torin Thielhelm, Dev Patel, Keshav Sharma, Satish Govindaraj, Alfred Marc Iloreta.
       OBJECTIVE: Otolaryngology-related conditions impose a significant burden on low-income countries (LICs), lower-middle-income countries (LMICs), and, at times, upper-middle-income countries (UMICs), where health care resources are limited. International research collaboration with high-income countries (HICs), like the United States, can address these disparities by advancing global health knowledge. As such, the underlying objective was to define trends of collaborative otolaryngology publications among the United States and LICs, LMICs, UMICs, and other HICs as well as assess the global distribution of these publications by region.
    STUDY DESIGN: A retrospective database review.
    SETTING: Scopus.
    METHODS: A bibliometric analysis of 163 collaborative publications (2018-2024) across 9 prominent US otolaryngology journals was conducted. Collaborations were categorized by country income level using the World Bank classification. Authorship positions, specialty classifications, and publication metrics were analyzed to assess representation across income groups.
    RESULTS: Publications involving LICs and LMICs were limited. LICs contributed 0.82% of authors, with no representation in significant positions, while LMICs contributed 2.07%, with 0.94% in significant positions. HICs dominated authorship, accounting for 92.54% of authors and 94.36% of significant positions. Collaborations with LICs and LMICs were mainly concentrated in specific regions, with Uganda and Egypt, respectively, being the top contributors from these categories. The majority of publications from LICs and LMICs appeared in Otolaryngology-Head and Neck Surgery and JAMA Otolaryngology.
    CONCLUSION: This is the first study to examine US-LIC/LMIC collaborations in otolaryngology, revealing limited inclusion of authors from these regions in key roles. Strengthening equitable partnerships is crucial to advancing global health equity in the field.
    Keywords:  global health; health care equity; international collaboration; otolaryngology; research trends
    DOI:  https://doi.org/10.1002/ohn.1266
  48. Front Aging Neurosci. 2025 ;17 1537119
    Synapses-associated research in Parkinson's disease: an explored trends analysis.
    Yan-Jun Chen, Ming-Rong Xie, Sheng-Qiang Zhou, Fang Liu.
       Background: The pathological features of Parkinson's disease (PD) include the formation of Lewy bodies composed mainly of aggregated alpha-synuclein (α-Syn) and extensive neurodegeneration. Synaptic dysfunction is a key factor contributing to disease progression among the various cellular and molecular mechanisms of PD. This study aims to analyze the research hotspots, frontier trends, and future directions of PD and synapses.
    Method: Relevant publications were obtained using the Web of Science database. Software CiteSpace, VOSviewer, and bibliometrix were used for visualization and quantitative analysis.
    Results: A total of 3,823 publications were included for analysis, and the number of publications related to the research topic showed an increasing trend from 2001 to 2024. North America, Asia, and Europe were the main research forces with high activity. The United States was the main leader in this field, followed by China and Italy. Emory University was the institution with the largest number of publications. Journal of Neuroscience was the core journal with a large number of publications. Dr. Calabresi, Paolo was a leader in the field of research. High-frequency keywords included PD, α-Syn, synaptic plasticity, basal ganglia, dopamine, substantia-nigra. In recent years, neuroinflammation has been the subject of active research.
    Conclusion: Communication and collaboration between different countries, institutions, and authors have promoted the development of this field. The research content mainly focused on α-Syn, synaptic plasticity, and mouse model. Neuroinflammation may be the direction of future research.
    Keywords:  Parkinson’s disease; alpha-synuclein; neuroinflammation; synapses; synaptic plasticity
    DOI:  https://doi.org/10.3389/fnagi.2025.1537119
  49. Front Oncol. 2025 ;15 1562621
    The rising influence of lipid metabolism in lung cancer: a global research perspective.
    Chaoqun Wang, Ming Lei, Wei Wang, Yuanyuan Jiang, Jiefeng Zhang, Yi Zhang, Bin Zhao, Wenyang Wang.
       Background: Lung cancer is a prevalent malignant neoplasm globally and the leading cause of cancer-related mortality, posing a significant threat to human health and imposing a considerable societal burden. Researchers have recently focused more on lipid metabolism in lung cancer. However, to date, there has been no bibliometric analysis of lung cancer in relation to lipid metabolism. This study used bibliometric methods to analyze the link between lipid metabolism and lung cancer.
    Methods: Publications on lung cancer and lipid metabolism from 1995 to 2024 were sourced from the Web of Science Core Collection (WoSCC). The Microsoft Excel, R-bibliometrix, CiteSpace, and VOSviewer software were used to analyze and visualize the data.
    Results: In this study, a total of 535 publications were identified, with a marked increase in the number of publications observed post-2016. Both China and the United States exerted substantial influence in this domain. Notably, the Chinese Academy of Sciences and Huazhong University of Science and Technology have demonstrated leadership in various aspects of lipid metabolism research related to lung cancer. Professor Ana Ramirez de Molina and Frontiers in Oncology were the most productive authors and journals respectively. Besides, keywords like "lipid metabolism", "lung cancer", "expression", "metabolism" and "growth" were central to current research and are expected to continue driving future trends in lung cancer and metabolism studies.
    Conclusions: Research on the relationship between lung cancer and lipid metabolism was still in its early stages. Targeting lipid metabolism in lung cancer represented a promising therapeutic strategy, as inhibiting key enzymes involved in lipid biosynthesis and uptake has the potential to impede cancer progression and mitigate drug resistance. This bibliometric study was the first to thoroughly summarize research trends and developments in this area over the past thirty years, providing scholars with updated insights and identifying future research directions.
    Keywords:  bibliometric; lipid metabolism; lung cancer; trend; visualized analysis
    DOI:  https://doi.org/10.3389/fonc.2025.1562621
  50. Drug Des Devel Ther. 2025 ;19 2749-2766
    Knowledge Mapping and Global Research Trends of Ginseng Polysaccharides: a Bibliometric Analysis with Visualizations from 1985 to 2023.
    Pingli Mo, Bowen Gao, Rui Wang, Shiying Huang, Qiugu Chen, Muxia Li, Jiazhen Wu, Shangbin Zhang, Jianping Chen.
       Background: Panax ginseng C. A. Meyer (Ginseng) has a lengthy historical background of utilization and is frequently utilized for the treatment and prevention of various diseases. In recent times, researchers have shown an increasing inclination towards investigating the extraction, purification, structural analysis, and pharmacological properties of polysaccharides present in ginseng. However, there was still a lack of comprehensive and integrated analysis of ginseng polysaccharides.
    Methods: This study employed the Web of Science Core Collection (WoSCC) as the data source and utilized software tools including Bibliometrix R Package, VOSviewer, and CiteSpace for the purpose of conducting data visualization and analysis of ginseng polysaccharides publications.
    Results: China emerged as the foremost and most impactful nation in the realm of ginseng polysaccharide research, fostering robust collaborative ties with Republic of Korea and the USA. Yifa Zhou was the most influential author and the International Journal of Biological Macromolecules exerted as the significant influence in this field. The reference DUBOIS M, 1956, ANAL CHEM, V28, P350 received the highest citations. Through a comprehensive examination results of keywords clustering, keywords with the strong burst, and trend topic, the research hot directions of ginseng polysaccharides were focused on structural analysis and pharmacological activities. Specifically, gut microbiota and oxidative stress were active research hotspots of investigating the pharmacological activities of ginseng polysaccharides at present, it also was corroborated in disciplinary category analysis.
    Conclusion: This study revealed the multidimensional field of research on ginseng polysaccharides. Current hot research directions encompassed structural analysis and pharmacological activities in this field, with research hotspots focused on exploring the pharmacological activities of ginseng polysaccharides in gut microbiota and oxidative stress.
    Keywords:  bibliometrics; ginseng polysaccharides; gut microbiota; oxidative stress; visualization
    DOI:  https://doi.org/10.2147/DDDT.S508387
  51. Front Immunol. 2025 ;16 1558926
    Bibliometric and visual analysis in the field of macrophages in Traditional Chinese Medicine from 2003 to 2023.
    Wenxin Zhang, Kaidi Zhao, Ruimin Ma, Minghan Ma, Yuqiong Du, Peng Fang.
       Objective: Macrophages are increasingly recognized as crucial therapeutic targets in the treatment of diverse pathological conditions. While considerable research has focused on macrophage-related mechanisms within Traditional Chinese Medicine (TCM), there remains a notable absence of comprehensive quantitative analyses in this field. This study aims to examine the evolutionary trajectory of macrophage-related research in TCM from 2003 to 2023, providing insights to guide future investigative directions.
    Methods: We searched for articles published between 2003 and 2023 from the Web of Science Core Collection (WoSCC) database and analyzed them using R software, VOSviewer and CiteSpace.
    Results: A total of 1,823 documents were obtained through the search. The results indicated that the number of publications between 2003 and 2023 exhibited an upward trend, with the majority of these documents originating from Chinese academic institutions and authored by Chinese scholars. This observation suggests a potential correlation with the growing prominence of Chinese medicine within China. Macrophage polarizations, a prominent focus in the study of macrophages, has also assumed an increasingly significant role in the domain of macrophages in TCM-related disciplines. The publication of these results also suggests that targeting macrophages in TCM for the treatment of some diseases is very promising, especially in ulcerative colitis, tumor-related diseases, and some liver diseases. This study provides a more comprehensive analysis of the current status and significant areas of research in the field of macrophage research in TCM, offering valuable insights for prospective research endeavors.
    Conclusion: Macrophage-related studies in TCM have garnered increasing attention from global scholars from researchers worldwide, and are expected to become a hotspot for targeting macrophages to develop new drugs to treat diseases in the future. This study comprehensively analyzes the current status and hotspots of macrophages in Chinese medicine, which can provide valuable references for future research.
    Keywords:  CiteSpace; Traditional Chinese Medicine; VOSviewer; bibliometrics; macrophages
    DOI:  https://doi.org/10.3389/fimmu.2025.1558926
  52. J Allergy Clin Immunol Glob. 2025 May;4(2): 100455
    Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview.
    Hugo W F Mak, Freya K L Chung, Philip H Li, Marcus Maurer.
       Background: The treatment of chronic spontaneous urticaria (CSU) remains a challenge despite novel therapies such as omalizumab. With growing international interest in research on CSU, a comprehensive review of the global productivity, collaborations, and trending topics in CSU research may help inform future directions in patient management.
    Objectives: This study aims to outline the trends in CSU research by using bibliometric analysis, focusing specifically on global productivity, collaborative efforts, and emerging research topics spanning from 1977 to 2023.
    Methods: Publications related to CSU, including original articles, reviews, and letters, were sourced from the Web of Science Core Collection, and statistical analyses were performed using the Bibliometrix package in R and IBM SPSS Statistics.
    Results: A total of 2940 publications from 77 countries were analyzed. CSU research activity has increased exponentially since 2010, with more than half of the publications (50.2% [1477 of 2940]) published since 2016. These publications appeared in allergy, immunology, and dermatology journals led predominantly by European, Asian, and American researchers. International collaborations rose from 11.3% to 22.2%. Shifts in research focus, such as a shift in treatments from antihistamines to omalizumab, and growing emphasis on quality of life were noted.
    Conclusion: This study revealed a dynamic and increasingly collaborative CSU research landscape, emphasizing the need for continuous global partnerships to enhance treatment outcomes and improve patients' quality of life. Challenges regarding access to advanced therapies persist, highlighting the importance of expanding international collaborations and inclusive research practices.
    Keywords:  Bibliometric; chronic; research; spontaneous; trends; urticaria
    DOI:  https://doi.org/10.1016/j.jacig.2025.100455
  53. J Diabetes Metab Disord. 2025 Jun;24(1): 103
    A scientometric analysis and visualization of research on fatty liver diseases in Iran from 2003 to 2023.
    Ehsaneh Taheri, Hamideh Ehtesham, Reza Safdari, Ahmad Hormati.
       Background: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide and is now a major global health threat. Due to the mechanistic links between these conditions, along with the rising prevalence of fatty liver disease, diabetes, and obesity, MAFLD (metabolic-associatedfatty liver diseases) was introduced as a new terminology and then updated to MASLD (Metabolic Dysfunction-associated Steatotic Liver Disease. These changes reflect a growing recognition of the importance of fatty liver and its associated health risks.
    Methods: This scientometric study analyzed publications on "fatty liver diseases" (FLD) indexed in Scopus from 2003 to 2023 in Iran. Online Analysis Platforms and VOSviewer were used to assess publication trends and identify research hotspots.
    Results: We retrieved 1,857 English articles on fatty liver diseases published between 2003 and 2023. The Journal of Hepatitis Monthly was notable for Iranian publications on fatty liver disease. Most publications were original articles and Dr. Sahebkar AH was the most prolific author. Iranian researchers primarily collaborated with scholars from the United States. The leading institution in terms of productivity was Tehran University of Medical Sciences.
    Conclusion: This study reveals an increasing trend in both the number of Iranian publications and the citations of articles in the field of FLD. We believe this study can serve as a roadmap for future research and policy development on fatty liver diseases, which are a significant public health concern in Iran. Additionally, new strategies are needed to foster multi-disciplinary research and enhance international cooperation.
    Supplementary Information: The online version contains supplementary material available at 10.1007/s40200-025-01606-8.
    Keywords:  Fatty liver disease; Scientometrics; VOSviewer
    DOI:  https://doi.org/10.1007/s40200-025-01606-8
  54. Leadersh Health Serv (Bradf Engl). 2025 Apr 21.
    Clinical leadership in nursing in an ever-changing world: a bibliometric analysis.
    Havva Yesildere Saglam, Fatmanur Sena Karakisla.
       PURPOSE: Leadership plays a critical role in improving the quality of care, minimizing risks to patients and staff and improving patient care outcomes. The purpose of this study is to analyze the structure of publications in the field of clinical leadership in nursing and to provide an overview of its development, trends and focus.
    DESIGN/METHODOLOGY/APPROACH: This study is descriptive bibliometric study. Data were collected from Web of Science on August 24, 2023. The population of the study consisted of 1,979 articles between 1994 and 2023 in the field of clinical leadership in nursing obtained from R Studio and WoS database.
    FINDINGS: The country where clinical leadership was most frequently studied was USA (n = 706). The most frequently used keywords by authors were leadership (843 times), nursing (329 times) and nurses (143 times). In the early years, the most frequently used trending topics were "quality," "culture," "change" and "leadership style," while in recent years the trending topics were "burnout" and "COVID-19."
    PRACTICAL IMPLICATIONS: Due to the limited knowledge on this subject, this study will make an important contribution to the literature and will shed light on new studies to be planned on clinical leadership.
    ORIGINALITY/VALUE: It has been observed that the issue of clinical leadership in nursing has become even more important in recent years following radical changes in the world such as pandemics and disasters. It has been observed that studies on this subject have increased rapidly in recent years. While the topics of job satisfaction, burnout and Covid-19 were frequently studied, it was observed that mentoring, collaboration, organization of new graduate nurses, moral difficulties and clinical leadership in nursing education were studied more limitedly.
    Keywords:  Bibliometric analysis; Clinical leadership; Clinical nursing; Nursing leadership
    DOI:  https://doi.org/10.1108/LHS-12-2024-0149
  55. Front Nutr. 2025 ;12 1494920
    Global trends in research on eating behaviors among overweight/obese children and adolescents: a bibliometric study from 2003 to 2023.
    Jiuyuan Wang, Wenjing Huang, Jiaqi Sun, Saiqiong Yin, Jiayi Lin, Pingan Liu, Guixiang Sun.
       Background: Despite the widespread interest in overweight/obese children and adolescents, there is a lack of bibliometric research on the factors influencing eating behaviors.
    Methods: Collated and screened research papers published between 2003 and 2023 on eating behaviors in children and adolescents affected by overweight or obesity, searched on January 1, 2024. The primary data, comprising complete records and referenced citations of publications, was extracted from the Web of Science Core Collection. Analysis of data using Bibliometrix of R package, CiteSpace, and VOSviewer.
    Results: A total of 2,142 articles were included. The United States had the most publications in the field and was also the center point for world collaborations. Harvard University had the most affiliated publications, while Luis Moreno was the most prolific author. NUTRIENTS was the most published journal. High-frequency keywords included Children, overweight, physical activity, body mass index, and childhood obesity. Research trends include Epidemiology and Environment factors of obesity; Health risks associated with childhood obesity; Key eating habits and interventions for childhood obesity; Prevention and treatment of childhood and adolescent obesity.
    Conclusion: This research provides a comprehensive overview of global trends and key areas in studying dietary behaviors among overweight/obese children and adolescents. It offers a detailed summary of recent advancements, emphasizing this field's critical principles and practices. By exploring these developments, the study highlights the growing importance of this research within global healthcare and suggests pathways for future research and applications.
    Keywords:  CiteSpace; bibliometric; children and adolescent; eating behaviors; overweight and obese; research focus
    DOI:  https://doi.org/10.3389/fnut.2025.1494920
  56. Quant Imaging Med Surg. 2025 Apr 01. 15(4): 2971-2986
    The insight to history and trends of transient elastography for assessing liver fibrosis-a bibliometric analysis.
    Amina Aierken, Yilizhati Azhati, Jing Wu, Yun-Fei Zhang, Alimujiang Mamuti, Maiwulanjiang Maimaiti, Chun-Hui Lv, Aliya Tulading, Repikaiti Yasheng, Ming-Juan Wang, Gang Yao, Tuerhongjiang Tuxun.
       Background: Transient elastography (TE) has become a prominent technique for the detection of fibrosis, owing to its non-invasive nature, rapid execution, safety, and ease of repetition. This study aims to conduct a bibliometric analysis of the historical development and trends in the application of TE for the assessment of liver fibrosis.
    Methods: In the Web of Science (Core Collection database), we selected the Science Citation Index Expanded database to search for relevant literature from 1 January 1983 to 20 November 2023. We performed a search using the following topic words: transient elastography, liver fibrosis. After screening according to the title, abstract and keyword and removing the repetition, the literature included in the study was finally determined, and full records were downloaded. Bibliometric analysis was performed using VOSviewer and CiteSpace.
    Results: Through the bibliometric visualization analysis of 577 articles, it was found that since TE was first reported for the measurement of liver fibrosis in 2003, the number of publications in this field has generally shown an upward trend, and the distribution of publications has shown a bimodal distribution, with peaks in 2010 and 2019. France and China have shown a high contribution in this field with a high number of publications. In terms of contributions from individual research centers, Yonsei University stands out prominently. Throughout the history of research in this field, early studies focused on chronic viral hepatitis, by comparing TE and Fibrosis-4, aspartate aminotransferase to platelet ratio index, FibroTest, liver biopsy and other liver fibrosis detection indicators to verify its diagnostic efficacy. Subsequently, the focus of research gradually shifted to non-alcoholic fatty liver disease and other liver diseases, and the scope of research extended to the establishment of prediction models and efficacy evaluation through TE.
    Conclusions: The application scope of TE is gradually expanding, and its safety, simplicity, rapidity, high accuracy, quantitative results, repeatability and good tolerance make it popular in clinical practice. Nowadays, the application of TE is not limited to the diagnosis of liver fibrosis, but has been extended to the establishment of prognostic models and efficacy evaluation of various liver diseases. To explore the deeper value of TE through new research methods such as machine learning models, radiate the advantages of TE to more liver diseases, and combine TE with a variety of non-invasive detection indicators to improve its application value, may be the future development and application prospect of TE in the field of liver fibrosis.
    Keywords:  Bibliometric; liver fibrosis; transient elastography (TE)
    DOI:  https://doi.org/10.21037/qims-24-2117
  57. J Formos Med Assoc. 2025 Apr 17. pii: S0929-6646(25)00184-6. [Epub ahead of print]
    Comment on "A bibliometric analysis of primary health care publication trends in the Asia-Pacific region from 2011 to 2023".
    Deng Ting, Liu Ping, Li Jierong, Gu Xiaomei.
      
    Keywords:  Evaluations; Health; Primary
    DOI:  https://doi.org/10.1016/j.jfma.2025.04.015
  58. Naunyn Schmiedebergs Arch Pharmacol. 2025 Apr 14.
    Research dynamics and drug treatment of renal fibrosis from a mitochondrial perspective: a historical text data analysis based on bibliometrics.
    Xu Li, Lan Hu, Qin Hu, Hua Jin.
      Renal fibrosis (RF) represents a significant public health challenge, necessitating the urgent identification of effective and safe therapeutic agents. Mitochondrial-targeted strategies have demonstrated considerable promise in restoring renal function and mitigating fibrosis. This study aims to examine the evolution of research and therapeutic interventions for RF from a mitochondrial perspective through bibliometric analysis. Literature retrieval was primarily conducted using the Web of Science Core Collection. Visual analysis was performed utilizing the Bibliometrix package (R- 4.4.2), CiteSpace 6.3.R1, and VOSviewer 1.6.19. A total of 819 documents were included for analysis. Significant contributions were made by researchers from China and the USA, with Nanjing Medical University leading in publication volume. Zhang Aihua and Huang Songming emerge as key scholars in the field, while the International Journal of Molecular Sciences is the journal with the highest publication output. Key research themes include oxidative stress, expression, injury, activation, mechanisms, and mitochondrial dysfunction. Mitochondrial-targeted approaches for treating RF can be categorized into six main strategies: mitochondrial biogenesis regulators, mitochondrial dynamics modulators, mitophagy inducers, oxidative stress regulators, NLRP3 inhibitors, and other mitochondrial-targeted therapeutic approaches. This study comprehensively examines the current state of RF research from a mitochondrial standpoint, summarizing key drugs and potential mechanisms of mitochondrial regulation. The findings aim to enhance scholarly understanding of the ongoing research trends and provide valuable insights for the development of targeted therapeutic agents.
    Keywords:  Bibliometrics; Mitochondria; Renal fibrosis; Visual analysis
    DOI:  https://doi.org/10.1007/s00210-025-04151-6
  59. Front Aging Neurosci. 2025 ;17 1536515
    Mapping the scientific research on exercise therapy for Alzheimer's disease: a scientometric study of hotspots and emerging trends.
    Shi Long Song, Wen Bing Yu, Xin Min Cai, Jie Ma, Lu Lu Zou, Li Li Gao, Shi Ming Li.
       Background: Alzheimer's disease (AD) is the most common form of dementia globally, placing a substantial economic burden on patients and society. Exercise serves as an adjuvant therapy for AD with a low incidence of related adverse events. As a non-pharmacological intervention, it has demonstrated significant potential in the therapy of AD.
    Objective: This study examines the key hotspots and emerging trends in exercise therapy for AD, offering valuable insights for researchers engaged in future research in this field.
    Methods: The Web of Science Core Collection database was utilized to search for literature on exercise therapy for AD from January 1, 2000, to November 1, 2024, with 1,372 relevant articles being identified. And CiteSpace 6.2.R4 and VOSviewer were used to evaluate the bibliometric indicators.
    Results: Since 2000, the number of publications in the field of exercise therapy for AD has been increasing. In addition to the well-known areas of research, such as the impact of exercise on cognitive function, the combination of exercise and medication therapy, the effects of exercise on specific symptoms, and the exercise with music therapy, the field may also focus on more novel topics. These include the integration of the design and implementation of exercise interventions, exercise and dendritic spines, and exercise and neurophysiological mechanisms. Furthermore, an analysis of emerging keywords reveals that the current main research direction is exploring the specific physiological mechanisms through which exercise affects AD. This includes three emerging trends: the impact of exercise on cognitive impairment in AD patients, the effects of exercise on brain-derived neurotrophic factor (BDNF) and Amyloid beta, and the influence of exercise on Stress and neuroinflammation.
    Conclusion: The research results indicate that interventions using exercise to alleviate the negative symptoms of AD, as well as combining exercise with medication for therapy, are gaining increasing attention from researchers. Meanwhile, novel topics such as exercise and music therapy, the design and implementation of exercise interventions, and neurophysiological mechanisms should also attract scholarly interest. Additionally, exploring the physiological mechanisms behind exercise therapy for AD could be a key focus for future research.
    Keywords:  Alzheimer’s disease; emerging trends; exercise therapy; research hotspots; visual analysis
    DOI:  https://doi.org/10.3389/fnagi.2025.1536515
  60. JB JS Open Access. 2025 Apr-Jun;10(2):pii: e24.00166. [Epub ahead of print]10(2):
    What Sets Indexed Orthopaedic Journals Apart? A Comparative Analysis of Quality Metrics Between Indexed Orthopaedic Journals and Nonindexed Orthopaedic Journals.
    Alex P Percle, Austin Hansen, Aaron Sheppard, Landon Tujague, Robert W Rutz, Patrick A Massey.
       Introduction: The PubMed database is used by many organizations as the benchmark for quality publications. This study aimed to identify quality metrics distinguishing orthopaedic journals indexed in PubMed from nonindexed journals. A second aim was to compare metrics of orthopaedic journals indexed in other major databases vs. nonindexed journals. We hypothesized that indexed orthopaedic journals would have several measurable attributes differentiating them from nonindexed journals.
    Methods: A list of all current orthopaedic journals in publication in 2021 was compiled. The journals were characterized based on their index status in PubMed, Master Journal List, Journal Citation Reports (JCR), MEDLINE, or Directory of Open Access Journals. Various journal attributes were collected and compared by indexed status. Each variable's association with indexed journals was determined through statistical analysis.
    Results: Of 478 evaluated journals, 271 were indexed by PubMed. Univariate analysis demonstrated significant associations between PubMed indexing and society affiliation, physician editorial leadership, print version availability, subscription availability, impact factor (IF) listed in JCR, use of Creative Commons licenses, Committee on Publication Ethics (COPE) membership, journals that require an article processing charge (APC), and earlier year of first issue (all with p < 0.001). Logistic regression of journals listed in any index demonstrates that COPE membership had the highest impact on indexed status (odds ratio = 34.19; 95% confidence interval 5.69-105.59; p < 0.001). The regression model also demonstrated that society affiliation, subscription availability, MD designation on website for editors, year of first issue, and number of physician editors have significant associations with indexed journals.
    Conclusion: COPE membership was the most distinguishing characteristic of indexed orthopaedic journals. Physician editorial leadership and society affiliation were also strong predictors of a journal having an indexed status. In addition, having a print version and/or subscription available, use of Creative Commons licenses, higher IF, longer publication history, and higher APC charge were associated more frequently with indexed journals. Authors should consider these factors when submitting articles to a journal and use caution submitting to journals which do not meet these quality metrics.
    DOI:  https://doi.org/10.2106/JBJS.OA.24.00166
  61. Eval Rev. 2025 Apr 18. 193841X251336839
    Evaluating Bibliometrics Reviews: A Practical Guide for Peer Review and Critical Reading.
    Anh-Duc Hoang.
      Along with discussing bibliometric analyses' limitations and potential biases, this paper addresses the growing need for comprehensive guidelines in evaluating bibliometric research by providing systematic frameworks for both peer reviewers and readers. While numerous publications provide guidance on implementing bibliometric methods, there is a notable lack of frameworks for assessing such research, particularly regarding performance analysis and science mapping. Drawing from an extensive review of bibliometric practices and methodological literature, this paper develops structured evaluation frameworks that address the complexity of modern bibliometric analysis, introducing the VALOR framework (Verification, Alignment, Logging, Overview, Reproducibility) for assessing multi-source bibliometric studies. The paper's key contributions include comprehensive guidelines for evaluating data selection, cleaning, and analysis processes; specific criteria for assessing conceptual, intellectual, and social structure analyses; and practical guidance for integrating performance analysis with science mapping results. By providing structured frameworks for reviewers and practical guidelines for readers to interpret and apply bibliometric insights, this work enhances the rigor of bibliometric research evaluation while supporting more effective peer review processes and research planning. The paper also discusses potential areas for further development, including the integration of qualitative analysis with bibliometric data and the advancement of field-normalized metrics, ultimately aiming to support authors, reviewers, and readers in navigating the complexities of bibliometrics and enhancing the meaningfulness of bibliometric research.
    Keywords:  VALOR framework; bibliometrics; research evaluation; review guideline; science mapping
    DOI:  https://doi.org/10.1177/0193841X251336839
  62. Anat Sci Educ. 2025 Apr 15.
    Unveiling disparity: A call to action for gender diversity in anatomy journal editorial teams.
    Buse Naz Çandır Gürses, Zekiye Karaca Bozdağ, Aslı Ceren Macunluoğlu, İlke Ali Gürses.
      This study aimed to determine the representation of women on the editorial teams of anatomy journals and to investigate the possible reasons for gender differences. The anatomy journals listed in the Web of Science Master Journal List and on the International Federations of Associations of Anatomy website were evaluated. The number, gender, and academic titles of editors-in-chief, associate editors, and editorial board members were recorded, along with the journals' continents, association/society memberships, quartiles, and impact factors. A total of 36 journals were analyzed. Ten out of 49 (20.41%) editors-in-chief, 71 out of 347 (20.46%) associate editors, and 285 out of 1065 (26.76%) of the editorial board members were women. The number of women on editorial teams was not related to the continent of the journal, any association/society, or quartile/impact values (p > 0.05). Asian journals had a significantly higher proportion of men associate editors compared to the higher proportion of women associate editors among North American journals (p < 0.05). There were 6 (16.67%) journals that provided information on the gender of the editorial team, 13 (36.11%) that provided academic titles, and 5 (13.89%) that published photographs. Women were rarely represented in all positions on the editorial teams of anatomical journals. The anatomical editorial community has an opportunity to make improvements toward gender equality by considering policies and strategies to overcome gender disparities.
    Keywords:  diversity; equity; gender equity; inclusion; women anatomists; women editors; women in anatomy; women in science
    DOI:  https://doi.org/10.1002/ase.70034
  63. Front Digit Health. 2025 ;7 1540362
    Mapping the research landscape of mHealth and technology in pediatric chronic illness: a bibliometric study.
    Esther Rodríguez-Jiménez, Javier Martín-Ávila, Selene Valero-Moreno, Marián Pérez-Marín.
       Introduction: The presence of a chronic disease during adolescence has been linked to an increased risk of developing psychosocial problems and a greater likelihood of experiencing difficulties during the transition to adulthood. In this regard, research has been conducted on the development of applications or programs based on new technologies to address the potential complications associated with self-management and coping with chronic diseases in adolescents.
    Method: The objective of the present study was to conduct a bibliometric analysis of the existing literature on the use of new technologies to enhance self-management and coping with chronic diseases during adolescence. This four-staged bibliometric analysis was conducted using the following software programs: HisCite, Bibexcel, Pajek, and VOSviewer. The programs were utilized for the extraction of data and the subsequent construction of graphs, which facilitate the visualization of existing networks between disparate authors, institutions, and terms.
    Results: The screening results shortlisted a total of 157 articles from an initial 207. The further analysis of these records indicated that the United States was the most prominent nation in terms of scientific output in the domain of digital applications designed to enhance self-management and coping in chronic diseases during adolescence.
    Discussion: The digital intervention in this specific population is primarily associated with the development of the mHealth app, along with the physical and psychological consequences that illness can entail. This research can serve as a reference for future bibliometric studies or scientific investigations in this field.
    Keywords:  adolescents; apps; chronic disease; digital intervention; mHealth; new technologies; pediatric; self-management
    DOI:  https://doi.org/10.3389/fdgth.2025.1540362
  64. J Multidiscip Healthc. 2025 ;18 1895-1911
    Chemotherapy-Induced Bone Marrow Suppression: A Bibliometrics Analysis.
    Jing Yue, Huili Shui, Gao Li, Bing Yang, Dongxin Tang.
       Objective: This study seeks to investigate the key research hotspots and evolving trends in chemotherapy-induced bone marrow suppression over the past two decades by employing bibliometric visualization analysis, thereby providing a robust theoretical and empirical foundation for advancements in both scientific understanding and clinical practice.
    Methods: Utilizing the Web of Science Core Database, a total of 6,110 documents were retrieved and analyzed using CiteSpace and VOSviewer software. This analysis traces and evaluates the current research status, key advancements, and development trajectories of chemotherapy-induced bone marrow suppression research from 2004 to 2023.
    Results: The analysis included 6,110 documents, revealing a significant upward trend in research volume. The United States (1,688 papers) and China (1,528 papers) are the leading contributors, with Cancer Chemotherapy and Pharmacology being the most prolific journal. Keyword burst detection identified key research focuses, including nasopharyngeal carcinoma, immunotherapy, and agents such as nivolumab and pembrolizumab. These findings indicate promising directions for further exploration, such as immunotherapy for nasopharyngeal carcinoma and innovative strategies for managing bone marrow suppression with specific drugs.
    Conclusion: Future research may concentrate on immune checkpoint inhibitors and nasopharyngeal carcinoma. Additionally, new treatment such as the natural compound curcumin has demonstrated protective effects during chemotherapy, effectively alleviating side effects. Nutritional support strategies significantly enhance patients' quality of life during treatment, while integrative approaches that combine traditional Chinese medicine with modern medical practices reveal the potential for synergistic effects. Together, these strategies could improve clinical outcomes and effectively address the challenges posed by chemotherapy-induced bone marrow suppression.
    Keywords:  VOSviewer; bibliometric analyses; chemotherapy-induced bone marrow suppression; citespace; visualization
    DOI:  https://doi.org/10.2147/JMDH.S507187
  65. J Dent Sci. 2025 Apr;20(2): 1262-1266
    A scientometric study on research trends and characteristics of ameloblastoma.
    Hui Li, Chenping Zhang, Wei Liu, Lanming Chen.
       Background/purpose: Ameloblastoma is a benign tumor derived from odontogenic epithelium in the jaws. The purpose of this study was to analyze the scientometric characteristics and research trends of ameloblastoma.
    Materials and methods: All the papers on ameloblastoma were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2014 and 2014-2024 in the analysis of research trends.
    Results: There were 2507 papers on ameloblastoma, with total citations of 34,691 and the h index of 70. The related disorders of the diagnosis of ameloblastoma were mandibular neoplasms, maxillary neoplasms, ameloblastic carcinoma, odontogenic cyst, lung neoplasms, and teratoma. Before 2014, bone graft/transplantation, osteotomy, reconstructive surgical procedures, surgical flaps, cell differentiation, and cytology were more frequent keywords. After 2014, biology research on BRAF protein, gene mutation, cytokeratin 19, biomarkers, epithelial mesenchymal transition, signal transduction, tumor microenvironment, and carcinogenesis were more frequent keywords. Clinical studies on cohort analysis, cone beam computed tomography, quality of life, fine needle aspiration biopsy, incisional biopsy, surgical margin, and hemi-mandibulectomy were more common. Experiment methods such as dog, tumor cell line, cell migration, gene expression, real time polymerase chain reaction, and western blotting were also more frequent keywords after 2014.
    Conclusion: This scientometric study elucidated the current scenario and research trends of ameloblastoma, and would help in improving in reciprocal collaboration and communication for investigations on this tumor.
    Keywords:  Ameloblastic carcinoma; Ameloblastoma; Bibliometrics; Metastasizing ameloblastoma; Odontogenic tumor
    DOI:  https://doi.org/10.1016/j.jds.2024.11.030
  66. J Dent Sci. 2025 Apr;20(2): 1252-1256
    A scientometric study on research trends and characteristics of burning mouth syndrome.
    Wei Liu, Ying Zhang, Qi Zhu, Lan Wu.
       Background/purpose: Burning mouth syndrome (BMS) is a chronic condition characterized by intraoral burning sensation and orofacial pain but without oral mucosal lesions. The purpose of this study was to analyze the scientometric characteristics and research trends of BMS.
    Materials and methods: All the papers on BMS were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and 2015-2024 in the analysis of research trends.
    Results: There were 924 papers on BMS, with total citations of 24,024 and the h index of 76. The related disorders of BMS were depression, xerostomia, pain, anxiety, glossodynia, taste disorder, nociception, paresthesia, analgesia, sleep disorder, diabetes mellitus, and neuralgia. Clonazepam was most common pharmacotherapy for BMS. After 2015, pharmacologic keywords including drug safety, aripiprazole, duloxetine, folic acid, hydrocortisone, and pregabalin were more frequent. Low level laser therapy, acupuncture, and cognitive behavioral therapy were the emerging nonpharmacologic strategies for BMS. Moreover, laboratory investigations on biomarkers, blood, genetics, interleukin 6, and tumor necrosis factor were more common. Various questionnaires, comorbidity, complication, anemia, hypertension, diabetes mellitus, and sleep were also more concerned after 2015.
    Conclusion: This scientometric study elucidated the current scenario and research trends of BMS, and would help in improving in reciprocal collaboration and communication for investigations on this condition.
    Keywords:  Bibliometrics; Burning mouth syndrome; Neurological factors; Psychological factors; Therapy strategy
    DOI:  https://doi.org/10.1016/j.jds.2025.01.009
  67. ACS Omega. 2025 Apr 08. 10(13): 12817-12836
    Advances and Applications of Micro- and Mesofluidic Systems.
    Larissa Araújo Oliveira Alves, John Hebert da Silva Felix, Antônio Átila Menezes Ferreira, Maria Tayane Barroso Dos Santos, Carlos Galvão da Silva, Larysse Maria Santiago de Castro, José Cleiton Sousa Dos Santos.
      Microfabrication technology has advanced scientific understanding and expanded our molecular control capabilities, enabling the development of 3D models in micrometer structures. The sizes of the fluidic channels are arranged in descending order, starting with the macro-, followed by the meso-, micro-, and nanoscale. These advances bring advantages and speed up biological and chemical experimental processes. Such miniaturized systems show significant advances, particularly in meso- and microreactors, through high-throughput screening. This work proposes a bibliometric analysis of the advances and applications of the Web of Science (WoS) database, analyzing the main highlights of the publications, indicators, and impact on knowledge production. In the past 20 years, approximately 3,934 documents published and cited, mainly by major world powers on micro- and mesofluidic systems, are increasingly expanding in the academic and industrial sectors.
    DOI:  https://doi.org/10.1021/acsomega.4c10999
  68. Urol Res Pract. 2025 Apr 04. 50(6): 332-342
    Gap of Research to Practice in IC/BPS: A Scientometric Study of Available Evidence.
    Helia Mostafaei, Hamidreza Ashayeri, Sayeh Afshar, Hadi Mostafaei, Tannaz Aghaei Badr, Hanieh Salehi-Pourmehr, Sakineh Hajebrahimi.
      Our main objective is to first characterize the current status of the research field of interstitial cystitis and bladder pain syndrome (IC/BPS). This is achieved by mapping, analyzing, and sub-analyzing the field with a scientometric approach, which provides insights into future research. In September 2023, the Scopus database was searched without restrictions on language and date. The following search query was used: Bladder* W/5 pain* W/3 syndrome* AND Interstitial* W/3 (Cystitis* OR Cystides) and the Scopus filters were used to exclude short surveys, book chapters, editorials, notes, and guidelines. The author, journal, institution data, keywords, average citation, countries, and sources were transformed using a Biblioshiny tool (A Shiny app for Bibliometrix), accounting for author spelling, institutional naming, and subgrouping variations. The search strategy yielded 1833 studies. The USA was the most cited country, with other countries showing significant growth in recent years. In terms of affiliations, TZU CHI University was the most relevant in this field (n = 154). The most relevant keywords were "female," "interstitial cystitis," "human," "cystitis interstitial," "male," and "cystalgia." The current topics in IC/BPS research are Genome-wide association and Cannabidiols. By understanding the past, scientific gaps, and the direction of the current research, researchers can aim for their research questions and conduct their research more organized. The scientific gaps of IC/BPS can be effectively understood by paying attention to the models used in this research, which are the results of the systemic analysis of the scientific products in this research field.
    Keywords:  Bibliometric; bladder pain syndrome; interstitial cystitis; scientometric study
    DOI:  https://doi.org/10.5152/tud.2025.24086
  69. Front Psychol. 2025 ;16 1515323
    Citation practices in applied linguistics: a comparative study of Chinese expert and novice authors.
    Xue Gong, Ruoxi Liu, Chuanbo Ji.
      Citation practices are crucial in academic discourse for both knowledge construction and interpersonal interaction. While prior research in academic English has explored citation practices among expert and novice authors, there is a notable gap in studies focusing on Chinese academic papers. Moreover, it remains uncertain whether insights from English-language corpora can be extrapolated to other linguistic contexts. This study presents a comparative analysis of citation practices among expert and novice authors within the field of Chinese Applied Linguistics. Utilizing a corpus of 715,000 Chinese words, we analyzed academic papers authored by both groups. Our findings reveal that citation practices between expert and novice authors are largely comparable. Specifically, integral citations were more prevalent than non-integral citations, with the cited authors predominantly occupying the subject position. In terms of citation form, the four types employed, in descending order of frequency, were summary, block quote, generalization, and quote. The analysis of reporting markers showed a predominance of discourse markers, followed by research markers, with cognitive markers being the least frequent. Notably, novice authors demonstrated certain deficiencies compared to their expert counterparts, including an overreliance on integral citations, a reduced use of generalization and block quote citations, and limited integration of information regarding reporting markers.
    Keywords:  Chinese applied linguistics; academic writing; citation practices; expert authors; novice authors
    DOI:  https://doi.org/10.3389/fpsyg.2025.1515323
  70. J Dent Sci. 2025 Apr;20(2): 1257-1261
    A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity.
    Wei Liu, Cheng Jiang, Xuemin Shen, Yunteng Wu, Jie Wei.
       Background/purpose: Oral involvement often constitutes the first sign of amyloidosis as a life-threatening disease that can lead to multiple organ impairment. The purpose of this study was to analyze the scientometric characteristics and research trends of amyloidosis involving the oral cavity.
    Materials and methods: All the papers on oral involvement of amyloidosis were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and 2015-2024 in the analysis of research trends.
    Results: There were 2540 relevant papers on amyloidosis involving the oral cavity, with total citations of 73,896 and the h index of 119. The related disorders were light chain amyloidosis, transthyretin amyloidosis, amyloid A amyloidosis, heart/cardiac amyloidosis, cardiomyopathy, kidney amyloidosis, and multiple myeloma. The trend of drug aspect, e.g. prednisone, colchicine, corticosteroid, doxorubicin, and vincristine before 2015 has changed to monoclonal antibody, daratumumab, tafamidis, proteasome inhibitor, carfilzomib, ixazomib, patisiran, pomalidomide, diflunisal, and doxycycline. Besides, the trend of clinical aspect has changed to complication, quality of life, risk factor, diagnostic imaging, prospective study, and early diagnosis after 2015. Herein, we highlight the awareness of early diagnosis and improve the access to care for amyloidosis, since oral involvement frequently constitutes the first sign of this disease.
    Conclusion: This scientometric study elucidated the current scenario and research trends of amyloidosis, underpinning that stomatologists can play roles in providing early recognition and timely diagnosis of amyloidosis when it involved the oral cavity.
    Keywords:  Amyloidosis; Bibliometrics; Early diagnosis; Macroglossia; Oral; Tongue
    DOI:  https://doi.org/10.1016/j.jds.2024.12.010
  71. Healthcare (Basel). 2025 Mar 25. pii: 726. [Epub ahead of print]13(7):
    Sarcopenia as a Prognostic Factor for the Outcomes of Surgical Treatment of Colorectal Carcinoma.
    Šimon Leščák, Martina Košíková, Sylvia Jenčová.
      Background/Objectives: Sarcopenia, defined as the progressive loss of muscle mass and function, is increasingly associated with worse outcomes in the surgical treatment of colorectal cancer (CRC). This paper focuses on analyzing the impact of sarcopenia as a prognostic factor on postoperative outcomes in CRC patients. The aim of the study is to identify the main factors influencing postoperative results. This will be accomplished via bibliometric analysis and highlighting the significance of muscle condition in the preoperative assessment of patients. Methods: The methodological approach involves analyzing bibliographic data from relevant scientific databases focused on sarcopenia and oncological surgery. The study employs a quantitative analysis of citations and collaborations among authors and institutions. The focus will be on research publications from 2013, when we first identified references to sarcopenia in the examined context. Results: The results show that sarcopenia significantly increases the risk of postoperative morbidity and mortality in CRC patients. Network analysis and keyword mapping reveal dominant research topics such as muscle condition, mortality, and postoperative complications. Meanwhile, we identify the need for standardized diagnostic methods for sarcopenia and their integration into clinical practice to improve predictive models and clinical approaches. Conclusions: These findings underscore the importance of interdisciplinary collaboration, preoperative assessment of muscle condition, and the implementation of standardized approaches to improve clinical outcomes for patients.
    Keywords:  bibliometric analysis; colorectal carcinoma; prognostic factor; sarcopenia; surgical treatment
    DOI:  https://doi.org/10.3390/healthcare13070726
  72. Int Endod J. 2025 Apr 18.
    Representation of women in executive and academic roles within scientific societies in the field of European Endodontology.
    Ana Arias, Henry F Duncan, Ruth Perez Alfayate, Jenifer Martín-González, Paula Riaza.
       AIM: To explore gender distribution within the field of Endodontology in Europe and to evaluate the representation of women in executive and academic roles within scientific societies as well as national and international conferences.
    METHODOLOGY: After ethical approval, an online questionnaire was developed and shared with the European Society of Endodontology and the 36 national Endodontic societies officially affiliated. The survey inquired about gender composition amongst members, executive committee roles, participation in major congresses and representation in leadership and authorship positions within scientific journals affiliated with these societies over the last 5 years. Information was also retrieved from publicly available websites. Genders of the first, last and corresponding authors from scientific journals were identified. The relative ratio of women amongst society members, executive committee roles, participation in major congresses and representation in leadership and authorship positions within scientific journals was calculated. The ratio of women in leadership positions was statistically compared with the mean relative ratio of women amongst society members using a one-sample t-test. The current proportion of women in individual roles was compared with the general proportion of women members using the Binomial test.
    RESULTS: Women account for 44% of members in endodontic societies. No significant discrepancy was observed in the overall representation of women as members in executive or editorial committees or in authorship positions within scientific journals in relation to the mean relative ratio of female society members but are significantly underrepresented in key positions such as society presidents, treasurers and scientific event organizers (p < .05). Additionally, women were significantly underrepresented at scientific events, both as lecturers and workshop leaders, at major congresses of national/international societies (p < .05). Few initiatives have been implemented to address these inequities; only three societies reported programmes aimed at promoting women in leadership or scientific roles.
    CONCLUSIONS: Within the limitations of this study, women appear to be fairly represented as members of executive and editorial committees in national endodontic societies and the ESE, as well as in authorship positions within scientific journals, but underrepresentation of women in positions of power and scientific forums persists. Some countries have begun implementing strategic measures to promote gender equity.
    Keywords:  academic role; authorship; endodontology; equality; executive role; gender equity
    DOI:  https://doi.org/10.1111/iej.14237
  73. J Law Med Ethics. 2025 Apr 14. 1-7
    Retractions of COVID-19-related Research Publications During and After the Pandemic.
    Ellie Rose Mattoon, Arturo Casadevall, Ferric C Fang.
      Retracted research publications reached an all-time high in 2023, and COVID-19 publications may have higher retraction rates than other publications. To better understand the impact of COVID-19 on the research literature, we analyzed 244 retracted publications related to COVID-19 in the PubMed database and the reasons for their retraction. Peer-review manipulation (18.4%) and error (20.9%) were the most common reasons for retraction, with time to retraction occurring far more quickly than in the past (13.2 mos, compared with 32.9 mos in a 2012 study). Publications focused on controversial topics were retracted rapidly (mean time to retraction 10.8 mos) but continued to receive media attention, suggesting that retraction alone may be insufficient to prevent the spread of scientific misinformation. More than half of the retractions resulted from problems that could have been detected prior to publication, including compromise of the peer review process, plagiarism, authorship issues, lack of ethics approvals, or journal errors, suggesting that more robust screening and peer review by journals can help to mitigate the recent rise in retractions.
    Keywords:  COVID-19; misconduct; peer review; research integrity; retractions
    DOI:  https://doi.org/10.1017/jme.2025.33
  74. Eur J Public Health. 2025 Apr 15. pii: ckaf053. [Epub ahead of print]
    Trends and future directions in childhood obesity research in the Nordic countries: a scientometric review.
    Fereshteh Baygi, Kimiya Gohari, Shirin Djalalinia, Jeanette Reffstrup Christensen, Jesper Bo Nielsen, Jens Søndergaard.
      In the Nordic countries, about one in five children aged 5-18 years live with overweight or obesity. This scientometric review analyses the patterns of childhood obesity research in the Nordic region to inform future strategic decisions for researchers and policymakers. Using VOSviewer (version 1.6.20), we conducted a visualization analysis of Nordic childhood obesity literature from Scopus, covering publication up to February 2024. Additionally, R version 4.4.0, and Microsoft Excel 2016 were used to support further analysis. The analysis included trends of scientific outputs, citations, patterns, collaboration network, and leading institutions. In the Nordic countries, 4123 documents were published from 1981 to 2024. A consistent increase was identified in collaborative studies since 1981. Sweden is playing a leading role in childhood obesity research. A strong partnership was noted between Danish and Swedish researchers, as well as between Finnish and Swedish researchers, with Sweden being a central hub of collaboration. The highly cited publications primarily focused on non-pharmacological public health interventions to reduce cardiovascular risk factors. Significant advancement has been achieved in understanding childhood obesity primarily focused on the filed medicine and nursing. Overweight, obesity, and metrics like body mass index have been extensively investigated, but no focus has been placed on medication as treatment. Despite the increasing research in this field, knowledge gaps exist in genetics, molecular biology, emerging pharmacological treatment as well as behavioral and social sciences. Future research should utilize the unique Nordic databases and advanced methods to improve understanding and inform effective public health interventions.
    DOI:  https://doi.org/10.1093/eurpub/ckaf053
  75. J Dent Sci. 2025 Apr;20(2): 1267-1272
    A scientometric study on research trends and characteristics of Behçet's disease.
    Wenying Zhang, Xuanning Chen, Linjun Shi, Liying Gu.
       Background/purpose: Behçet's disease (BD) is a chronic systemic vasculitis characterized by recurrent oral and genital ulcers, skin lesions, and uveitis. The purpose of this study was to analyze the scientometric characteristics and research trends of BD.
    Materials and methods: All the articles on BD were comprehensively retrieved from the Scopus database. Regional comparison (Turkey versus outside of Turkey) and chronological comparison (before 2010 versus after 2010) were performed.
    Results: Among the 7023 articles on BD, Turkey was the country publishing most articles (2012 articles). In Turkey, questionnaire, quality of life, depression, and scoring system were distinctive keywords. In outside of Turkey, allele, gene expression, cytokine, interleukin 6, tumor necrosis factor-alpha, and phenotype were distinctive keywords. The trend of diagnostics mainly angiography before 2010 has changed to computed tomographic angiography, echocardiography, and optical coherence tomography. The trend of biology research has changed to research on metabolism, gene expression, allele, biomarkers, and genetic susceptibility after 2010. The trend of drug aspects mainly oral drug administration before 2010 has changed to drug withdrawal, drug dose reduction, drug safety, drug megadose, adalimumab, thalidomide, and salazosulfapyridine after 2010.
    Conclusion: This scientometric study elucidated the current scenario and research trends of BD, and would help in improving in reciprocal collaboration and communication for investigations on this disease.
    Keywords:  Behcet's syndrome; Bibliometrics; Dentistry; Dermatology; Turkey; Uveitis
    DOI:  https://doi.org/10.1016/j.jds.2024.11.010
  76. Ocul Oncol Pathol. 2025 Apr;11(1): 21-29
    Female Representation in Ophthalmic Oncology and Pathology: An Analysis of Scholarship and Leadership.
    Ogul E Uner, Birkaran Sadhar, Lillian Huang, Maxim Breakstone, Jesse L Berry, Dan S Gombos, Prithvi Mruthyunjaya, Alison H Skalet.
       Introduction: Female representation in ophthalmic oncology and pathology is unknown. We evaluated gender-based trends in authorship and leadership in these fields, focusing on intraocular tumors.
    Methods: Articles containing "uveal melanoma" (UM), "retinoblastoma" (Rb), "primary intraocular lymphoma" (PIOL), "choroidal metastasis" (CM), and articles in Ocular Oncology and Pathology (OOP) were searched on PubMed and author names obtained. Leadership/awards from 4 international ophthalmic oncology and pathology societies were recorded. GenderAPI was used to predict gender.
    Results: Among 4,245 UM, 9,660 Rb, 141 PIOL, 353 CM, and 568 OOP authors, more males were first (range, 52-67%) and last authors (range, 69-76%). Analysis of the 4 keywords showed overall female authorship increased from 2011 to 2016 to 2017-2022 (35%-40%, p < 0.001), with an increase in both first (45%-47%, p = 0.03) and last authorship (26%-33%, p < 0.001). Female first authors were more likely to publish with female last authors (Rb OR 1.72, p < 0.001; OOP OR 2.04, p = 0.01). Males held more leadership roles/awards in societies.
    Conclusion: Female representation in ophthalmic oncology and pathology has grown but gender disparities remain. Female first authors were more likely to publish with female last authors. Most society leaders and awardees were male. Cultivating mentorship through professional organizations may help achieve gender parity.
    Keywords:  Choroidal metastasis; Diversity-Equity-Inclusion; Female representation; Gender; Ocular oncology; Ocular pathology; Ophthalmic oncology; Ophthalmic pathology; Primary intraocular lymphoma; Retinoblastoma; Uveal melanoma
    DOI:  https://doi.org/10.1159/000542560
  77. J Orthop Res. 2025 Apr 12.
    OREF Resident Research Symposia: An Important Pipeline for Prospective Orthopaedic Surgeon-Scientists.
    Mathangi Sridharan, Nicole J Newman-Hung, Charlotte Wahle, Frank Petrigliano, Nicholas M Bernthal, Lauren E Wessel.
      Non-governmental educational programs such as the annual Orthopaedic Research and Education Foundation (OREF) Resident Research Symposia aim to elevate and fund trainee research endeavors. This study investigates the translation of research recognized at the Resident Research Symposia into peer-reviewed publication and the rate of awardees who pursue academic careers after training. Awards from the OREF Resident Research Symposia between 2008 and 2023 were aggregated. Characteristics of awardees and projects were noted. Conversion to publication and journal characteristics were identified by indexing major research databases. The current practice type and specialty of each trainee was queried using the American Academy of Orthopedic Surgeons roster and institutional sites. Descriptive statistics, univariate and multivariate regression models were performed. Primary outcomes included rates of OREF symposia presentation conversion to publication and trainees pursuing a career in academia. Three hundred and eighty-nine awards were included with 72 (18.5%) females and 317 (81.5%) males. One hundred and forty-two (36.5%) were first place awards, 101 (25.9%) second place, 131 (33.7%) third place, and 15 (3.9%) presenter's choice, across five regions. Basic science projects were more likely to win first-place awards (p = 0.001). Awarded projects translated to 300 (77%) peer-reviewed publications, with an average impact factor of 1.78 ± 1.65. Male and first-place awardees were more likely to publish (p = 0.014, p = 0.001). The current practice types of 376 distinct awardees were identified with 149 awardees currently practicing in academia (42.3%). Awardees that successfully published their projects (p < 0.001), and those from the Mid-Atlantic region (p = 0.01) were more likely to pursue academic careers. Research awarded at the OREF symposium translates to peer-reviewed publication at a high rate, and awardees enter academia at a disproportionately high rate. OREF provides an effective platform to identify and support budding surgeon-scientists, which is vital given that musculoskeletal research is historically underfunded at a national level.
    Keywords:  OREF; academia; pipeline; publication; resident education
    DOI:  https://doi.org/10.1002/jor.26083
  78. Sensors (Basel). 2025 Apr 04. pii: 2291. [Epub ahead of print]25(7):
    IoT Sensing for Advanced Irrigation Management: A Systematic Review of Trends, Challenges, and Future Prospects.
    Ahmed A Abdelmoneim, Hilda N Kimaita, Christa M Al Kalaany, Bilal Derardja, Giovanna Dragonetti, Roula Khadra.
      Efficient water management is crucial for sustainable agriculture, and the integration of Internet of Things (IoT) technologies in irrigation systems offers innovative solutions to optimize resource use. In this systematic review, the current landscape of Internet of Things (IoT) applications in irrigation management was investigated. The study aimed to identify key research trends and technological developments in the field. Using VOSviewer (CWTS, Leiden, The Netherlands) for bibliometric mapping, the influential research clusters were identified. The analysis revealed a significant rise in scholarly interest, with peak activity between 2020 and 2022, and a shift towards interdisciplinary and applied research. Additionally, the content analysis revealed prevalent agricultural applications, frequently employed microcontroller units (MCUs), widely used sensors, and trends in communication technologies such as the increasing adoption of low-power, scalable communication protocols for real-time data acquisition. This study not only offers a comprehensive overview of the current status of IoT integration in smart irrigation but also highlights the technological advancements. Future research directions include integrating IoT with emerging technologies such as artificial intelligence, edge computing, and blockchain to enhance decision-support systems and predictive irrigation strategies. By examining the transformative potential of IoT, this study provides valuable insights for researchers and practitioners seeking to enhance agricultural productivity, optimize resource use, and improve sustainability.
    Keywords:  bibliometric analysis; digital agriculture; internet of things (IoT); smart agriculture; soil moisture; wireless sensor networks (WSN)
    DOI:  https://doi.org/10.3390/s25072291
  79. Nature. 2025 Apr;640(8059): 591
    These are the most-cited research papers of all time.
    Richard Van Noorden.
      
    Keywords:  Bioinformatics; Computer science; Machine learning; Physics; Publishing; Software
    DOI:  https://doi.org/10.1038/d41586-025-01124-w
  80. PLoS One. 2025 ;20(4): e0320347
    Geographical and disciplinary coverage of open access journals: OpenAlex, Scopus, and WoS.
    Abdelghani Maddi, Marion Maisonobe, Chérifa Boukacem-Zeghmouri.
      This study aims to compare the geographical and disciplinary coverage of OA journals in three databases: OpenAlex, Scopus and the Web of Science (WoS). We used the Directory of Open Access Scholarly Resources (ROAD), provided by the ISSN International Centre, as a reference to identify OA active journals (as of May 2024). Among the 62,701 active OA journals listed in ROAD, the WoS indexes 6,157 journals, Scopus indexes 7,351, while OpenAlex indexes 34,217. A striking observation is the presence of 24,976 OA journals exclusively in OpenAlex, whereas only 182 journals are exclusively present in the WoS and 373 in Scopus. The geographical analysis focuses on two levels: continents and countries. As for disciplinary comparison, we use the ten disciplinary levels of the ROAD database. Moreover, our findings reveal a similarity in OA journal coverage between the WoS and Scopus. However, while OpenAlex offers better inclusivity and indexing, it is not without biases. The WoS and Scopus predictably favor journals from Europe, North America and Oceania. Although OpenAlex presents a much more balanced indexing, certain regions and countries remain relatively underrepresented. Typically, Africa is proportionally as under-represented in OpenAlex as it is in Scopus, and some emerging countries are proportionally less represented in OpenAlex than in the WoS and Scopus. These results underscore a marked similarity in OA journal indexing between WoS and Scopus, while OpenAlex aligns more closely with the distribution observed in the ROAD database, although it also exhibits some representational biases.
    DOI:  https://doi.org/10.1371/journal.pone.0320347
  81. Infect Dis Clin Microbiol. 2025 Mar;7(1): 58-65
    Predictors for Publication of Specialty Theses in the Field of Infectious Diseases and Clinical Microbiology.
    Pelin İrkören, Elif Agüloğlu-Bali, Oğuz Usta, Arzu Şenol, Barış Manavlı, Büşra Tanır, Esra Gürbüz, Halime Araz, Işıl Deniz Alıravcı, İlkay Nur Can, Kübra Demir-Önder, Melike Coşkunpınar-Törüyenler, Mustafa Deniz, Riyad Boran, Serpil Mızrakçı, Şükran Sevim Akıl, Taliha Pala-Karakök, Türkam Tüzün, Yasemin Çakır-Kıymaz, Fatma Yekta Ürkmez-Korkmaz, Yeşim Uygun-Kızmaz, Selçuk Özger, Önder Ergönül.
       Objective: Specialty theses in the field of infectious diseases and clinical microbiology (IDCM) play an important role in shaping medical knowledge, yet their publication in scientific journals remains a critical concern. We reviewed the theses of the IDCM specialty program, analyzed the publication rates in scientific journals, and made some recommendations for the future.
    Materials and Methods: We analyzed the registered IDCM theses in the electronic database of the Council of Higher Education (YÖK, Ankara) between 1984 and 2021. Specialty theses from other medical fields, PhD and master theses, were excluded from the study.
    Results: Out of 1265 theses, 1061 were included after exclusion criteria were applied. The study revealed that 647 (61%) of residents were female. Of 1061 authors, 117 (11%) received financial support during the preparation of the thesis. The most common thesis topics were viral hepatitis, healthcare-associated infections, antibiotic susceptibility, zoonotic diseases, febrile neutropenia, and sepsis. The predominant type of study design was observational (88%). Notably, 27 (3%) were randomized controlled trials. The overall rate of publication in a peer-reviewed journal was 25%. Nonetheless, 117 (11%) theses were published in the journals indexed in the Science Citation Index (SCI) or the Science Citation Index-Expanded (SCI-E). The median time from the presentation of theses to publication was four years.
    Conclusion: The publication rate of specialty theses in scientific journals in the field of IDCM was found to be low. Publication of the thesis as a scientific manuscript should be a part of the residency program and the completion process of the thesis. All the residents or young specialists should be encouraged to submit their theses for publication.
    Keywords:  publications; specialty; theses
    DOI:  https://doi.org/10.36519/idcm.2025.492
  82. Animals (Basel). 2025 Mar 24. pii: 931. [Epub ahead of print]15(7):
    From Cow to Climate-Tracing the Path of Dairy Sustainability: Unveiling the Impact on Sustainable Development Goals Through Bibliometric and Literature Analyses.
    Douglas Mwirigi, Mária Fekete-Farkas, Csaba Borbély.
      Archeological evidence shows that dairy farming dates to the early Neolithic era in Europe, the Middle East, Asia, and Africa. Over time, it has evolved from domestication to intensive dairy farms with large, high-tech processing units. Dairy farming has contributed to economic growth, food production, employment, and processing industries. Nonetheless, it has been identified as a major contributor to climate change. This study explores the literature on dairy farming and sustainable development goals (SDGs) to identify current scholarly developments since the formulation and adoption of the SDGs in 2015 and themes for future research. This paper argues that sustainability shortfalls in dairy farming are primarily driven by human processes associated with commercialization and industrialization rather than the animals themselves, although biological emissions remain an inherent factor. Data were analyzed using R package, Excel, NVIVO, and VoS Viewer. A review of the literature showed that dairy farming and its contribution to sustainability has gained more scientific interest since 2015. Moreover, livestock management, feed production and management, stakeholder management, logistics and supply chain management, and waste management are the sources of environmental adversities associated with dairy farming. Notably, these are human processes developed from the commercialization of dairy farming and involve multiple stakeholders across the supply chain. While solutions are embedded within these processes, innovation emerges as a key driver of sustainability and a source of opportunities to strengthen sustainability in the dairy farming sector and achieve SDGs. Sustainability strategies, such as sustainable intensification, multifunctional agriculture, and agro-ecology should be implemented to improve sustainability in the dairy sector.
    Keywords:  bibliometric analysis; climate; cow; dairy farming; environmental impact; milk production; sustainability; sustainable development goals; sustainable practices
    DOI:  https://doi.org/10.3390/ani15070931
  83. PLoS One. 2025 ;20(4): e0320334
    Research citations building trust in Wikipedia: Results from a survey of published authors.
    Carlos Areia, Kath Burton, Mike Taylor, Charles Watkinson.
       METHODS: A short survey was distributed to 40,402 authors of papers cited in Wikipedia (n=21,854 surveys sent, n=750 complete responses received). The survey gathered responses from published authors in relation to their views on Wikipedia's trustworthiness in relation to the citations to their published works. The unique findings of the survey were analysed using a mix of quantitative and qualitative methods using Python, Google BigQuery and Looker Studio.
    RESULTS: Overall, authors expressed positive sentiment towards research citation in Wikipedia and researcher engagement practices (mean scores >7/10). Sub-analyses revealed significant differences in sentiment based on publication type (articles vs. books) and discipline (Humanities and Social Sciences vs. Science, Technology, and Medicine), but not access status (open vs. closed access).
    CONCLUSIONS: This study provides unique insights into author perceptions of Wikipedia's trustworthiness. Further research is needed to deepen the understanding of the benefits for researchers and publishers including academic citations in Wikipedia.
    DOI:  https://doi.org/10.1371/journal.pone.0320334
  84. An Acad Bras Cienc. 2025 ;pii: S0001-37652025000200901. [Epub ahead of print]97(2): e20231335
    Cannabis-Bacteria Interaction: Trends in Secondary Metabolites, Biocontrol, and By-products.
    Paola Alzate, Mónica J Henao-López, Katherin Castro-Ríos, Claudia N Montoya-Estrada.
      In the last decade, the interest in cannabis cultivation has grown significantly, driven by its various applications and the presence of key cannabinoids such as cannabidiol (CBD) and cannabigerol (CBG). However, this increase in production has heightened susceptibility to contaminants, especially microorganisms, such as pathogenic bacteria, which pose risks to both human health and the plant itself. Nonetheless, a promising outlook emerges with the biological utilization of certain bacterial species. This study focused on a bibliometric evaluation of the interaction between Cannabis and bacteria, analyzing research trends related to metabolites, biocontrol, and by-products. To achieve this, scientific literature was reviewed in databases such as Scopus and Web of Science (WOS) from 2000 to 2023. The data was processed and analyzed using methodologies such as "Tree of Science" (ToS) and Prisma, using tools like R-Studio and Bibliometrix. The results highlight two predominant areas in this interaction: the application of biotechnology to enhance cultivation and utilize metabolites for medical purposes and the assessment of antibacterial properties in Cannabis extracts and essential oils, along with the use of beneficial bacteria for biocontrol in cannabis plants. Several avenues for future research are proposed, considering identified knowledge gaps.
    DOI:  https://doi.org/10.1590/0001-3765202520231335
  85. Nature. 2025 Apr;640(8059): 593-594
    Science's golden oldies: the decades-old research papers still heavily cited today.
    Richard Van Noorden.
      
    DOI:  https://doi.org/10.1038/d41586-025-01126-8
  86. World Neurosurg. 2025 Apr 16. pii: S1878-8750(25)00337-7. [Epub ahead of print] 123981
    Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus: Bibliometric Analysis and Literature Review.
    Wenju Bai, Tengwu Chang, Kamiran Halike, Jinyong Li, Xiaoyuan Huang, Xv Zhang, Jichao Wang.
      Idiopathic normal pressure hydrocephalus (iNPH) is a progressive neurological disorder characterized by normal intracranial pressure, ventriculomegaly, gait disturbances, cognitive impairment, and urinary dysfunction, with an unknown etiology and predominantly affecting elderly populations. iNPH frequently coexists with Alzheimer's disease (AD), and differentiating dementia-subtype iNPH from AD remains clinically challenging. In this review, we demonstrate that cerebrospinal fluid (CSF) biomarkers may aid differential diagnosis, correlate with cognitive impairment, and predict shunt surgery outcomes. The CSF biomarkers investigated include AD-associated markers (amyloid-β [Aβ] and tau proteins). Our analysis integrates bibliometric methodologies to map research trends. Advancements in understanding Aβ and tau pathology may offer novel diagnostic and therapeutic strategies for iNPH.
    Keywords:  Alzheimer's disease; amyloidβ; cerebrospinal fluid biomarkers; idiopathic normal pressure hydrocephalus; tau
    DOI:  https://doi.org/10.1016/j.wneu.2025.123981
  87. Arch Dermatol Res. 2025 Apr 12. 317(1): 705
    Psychodermatology: a bibliometric perspective on dermatologic and psychiatric intersections.
    Waseem Hassan, Antonia Eliene Duarte.
      
    DOI:  https://doi.org/10.1007/s00403-025-04233-8
  88. Front Digit Health. 2025 ;7 1559570
    Mobile health (mHealth) technologies for fall prevention among older adults in low-middle income countries: bibliometrics, network analysis and integrative review.
    Michael Joseph Dino, Ladda Thiamwong, Rui Xie, Ma Kristina Malacas, Rommel Hernandez, Patrick Tracy Balbin, Joseph Carlo Vital, Jenica Ana Rivero, Vivien Wu Xi.
       Introduction: mHealth technologies offer promising solutions to reduce the incidence of falls among older adults. Unfortunately, publications on their application to Low-Middle Income Countries (LMIC) settings have not been collectively examined.
    Methods: A triadic research design involving bibliometrics, network analysis, and model-based integrative review was conducted to process articles (n = 22) from 629 publications extracted from major databases using keywords related to mHealth, falls prevention, and LMIC. The web-based application Covidence and stand-alone VosViewer software were used to process data following previously published review standards.
    Results: Published articles in the field feature multidisciplinary authorships from multiple scholars in the domains of health and technology. Network analysis revealed the most prominent stakeholders and keyword clusters related to mHealth technology features and applications in healthcare. The papers predominantly focused on the development of mHealth technology, usability, and affordances and less on the physiologic and sociologic attributes of technology use. mHealth technologies in low and middle-income countries are mostly smartphone-based, static, and include features for home care settings with fall detection accuracy of 86%-99.62%. Mixed reality-based mobile applications have not yet been explored.
    Conclusion: Overall, key findings and information from the articles highlight a gradually advancing research domain. Outcomes reinforce the need to expand the focus of mHealth investigations to include emerging technologies, update current technology models, create a more human-centered technology design, test mHealth technologies in the clinical setting, and encourage continued cooperation between and among researchers from various fields and environments.
    Keywords:  bibliometrics; fall prevention; fall risk; integrative review; low-middle income countries; mHealth; network analysis; older adults
    DOI:  https://doi.org/10.3389/fdgth.2025.1559570
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