bims-evares Biomed News
on Evaluation of research
Issue of 2025–03–30
eighty papers selected by
Thomas Krichel, Open Library Society
  1. Cardiotoxicity induced by chemotherapy and immunotherapy in cancer treatment: a bibliometric analysis.
  2. Twenty years of research on exercise-induced fatigue: A bibliometric analysis of hotspots, bursts, and research trends.
  3. Global research trends and hotspots on imaging of bladder cancer: A bibliometric and visual analysis from 1981 to 2023.
  4. The 100 most cited articles in androgenetic alopecia: A bibliometric analysis.
  5. Hotspots and frontiers in patent foramen ovale research: a bibliometric and visualization analysis from 2003 to 2023.
  6. Uncovering global research frontiers in deubiquitinating enzymes and immunotherapy: A bibliometric study.
  7. Global status and trends of exosomes in neurodegenerative diseases from 2014 to 2023: a bibliometric and visual analysis.
  8. Bibliometric analysis of case-control studies on the association between HLA alleles and multiple sclerosis in adults.
  9. Fundamental knowledge and research regarding the role of immunity in triple-negative breast cancer from 2014-2024: A bibliometric analysis.
  10. Research hotspots and trends of skin barrier in atopic dermatitis in the past 24-year: a bibliometric analysis.
  11. Bibliometric analysis of autophagy in the diagnosis and treatment of osteosarcoma: a bibliometric analysis (2007-2023).
  12. A Bibliometric Analysis of HPV-Positive Oropharyngeal Squamous Cell Carcinoma from 2000 to 2023.
  13. Top 100 Most-Cited Papers on Temporomandibular Disorders in Children: A Bibliometric Analysis.
  14. Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): A Bibliometric Analysis of Publication Trends.
  15. A bibliometric analysis of blunt cerebrovascular injury: the top 50 most instrumental articles.
  16. A Bibliometric Analysis of Global Research Trends in Elderly Population Diseases.
  17. Patient Safety Culture Research: A Bibliometric Analysis From 2001 to 2023.
  18. Bibliometric and visual analysis of drug-specific immunotherapy from 1990 to 2024.
  19. Uveitis output in high-impact clinical ophthalmology journals: a bibliometric analysis.
  20. Global trends in esophageal cancer and metabolic syndrome research: bibliometric analysis and visualization from 1995 to 2024.
  21. Centenary Progress on Orchidaceae Research: A Bibliometric Analysis.
  22. RETRACTION: A Bibliometric Analysis of Global Research on Microbial Immune Microenvironment in Melanoma From 2012 to 2022.
  23. Artificial intelligence in obstructive sleep apnea: A bibliometric analysis.
  24. Evaluation of Research Productivity Among Academic Oculoplastic Surgeons Using the Relative Citation Ratio.
  25. Research Status and Trends of Gut Microbiota and Intestinal Diseases Based on Bibliometrics.
  26. Comprehensive Global Analysis of Future Trends in Artificial Intelligence-Assisted Veterinary Medicine.
  27. Knowledge Mapping and Global Trends in Simulation in Medical Education: Bibliometric and Visual Analysis.
  28. Four Decades of Progress: Evaluating Saudi Arabia's Research Publications in Pharmaceutical Sciences.
  29. The current state and development trends of frailty research in diabetic patients: a bibliometric analysis.
  30. Mapping the Evolving Trend of Research on Skeletal Class II Malocclusion Treated With Orthognathic Surgery: A Bibliometric and Visualized Analysis.
  31. Global research trends and emerging hotspots in acute high altitude illness: a bibliometric analysis and review (1937-2024).
  32. A bibliometric and visualized analysis of interventional treatment for intracranial atherosclerotic stenosis (from 2004 to 2023).
  33. The Current Research Landscape on the Machine Learning Application in Autism Spectrum Disorder: A Bibliometric Analysis From 1999 to 2023.
  34. A Bibliometric Analysis of Immunotherapy in Diffuse large B-cell lymphoma from 2004 to 2024.
  35. A Bibliometric Analysis of Research Trends in Psychological Interventions for Stroke Survivors: Focusing on Resilience and Psychological Well-Being (2000-2024).
  36. Global trends of laser bone ablation: bibliometric analysis of publications from 1979 to 2023.
  37. Analysis of the Highest Altmetrics-scored Articles in Emergency Medicine Journals.
  38. Mapping the Evolution of IBD Treatment: A Bibliometric Study on Biologics and Small Molecules.
  39. Identifying research activity on brain ultrasonography in craniocerebral diseases by bibliometric and visualized analysis of a 20-year journey of global publications.
  40. Exploring the relationship between social media dependence and internet addiction among college students from a bibliometric perspective.
  41. Emerging patterns in nanoparticle-based therapeutic approaches for rheumatoid arthritis: A comprehensive bibliometric and visual analysis spanning two decades.
  42. Global research trends in mind body therapies: a bibliometric analysis.
  43. Comprehensive bibliometric analysis and perspectives on therapies targeting colon cancer stem cells over a 40-year period.
  44. Predictors of Academic Productivity in Cardiac Surgeons: Quality Over Quantity.
  45. When COVID-19 meets diabetes: A bibliometric analysis.
  46. Repetitive Transcranial Magnetic Stimulation in Stroke Rehabilitation: A Bibliometric Review.
  47. Controversies in Pediatric Asthma: A Bibliometric Evaluation.
  48. Migration and Women's Health Research (2000-2023): A bibliometric analysis of trends and gaps.
  49. Research trends on spinal muscular atrophy from 1995 to 2023: A bibliometric analysis.
  50. Unveiling the nexus: A bibliometric analysis of nano plastic's health impact.
  51. Bibliometric Analysis of Antipsychotic-induced Metabolic Disorder from 2006 to 2021 Based on WoSCC Database.
  52. A Bibliometric Analysis of hypertension and anxiety from 2004 to 2022.
  53. Progress and Prospects of Research on the Impact of Mental Health of Youth Sailors-A Bibliometric-Based Analysis.
  54. Bibliometric analysis of systemic lupus erythematosus during pregnancy from 2003 to 2024.
  55. Artificial Intelligence in the Diagnosis of Neurological Diseases Using Biomechanical and Gait Analysis Data: A Scopus-Based Bibliometric Analysis.
  56. Geographic Location Markedly Affects Academic Productivity of Pediatric Orthopaedic Surgeons.
  57. Unraveling the Neuropharmacological Properties of Lippia alba: A Scientometric Approach.
  58. Applications of Machine Learning (ML) in the context of marketing: a bibliometric approach.
  59. Measuring the Longitudinal Impact of a Health Professions Education Academy on Scholarship: A Bibliometric Analysis.
  60. Comprehensive bibliographic study of the framework of complex generic drugs.
  61. A Metrology Informatics Investigation of Conversion Therapy in Hepatocellular Carcinoma: 2014-2023.
  62. Harnessing Artificial Intelligence for Sustainable Agriculture: A Comprehensive Scientometric Review.
  63. Assessing the prevalence, quality and compliance of data-sharing statements in gastroenterology publications: a cross-sectional analysis.
  64. Evaluation of retracted publications related to oral health: a scoping review.
  65. An analysis of periodontology theses in Türkiye: Ph.D. vs. specialization program.
  66. The Significance of Probiotics in Aquaculture: A Review of Research Trend and Latest Scientific Findings.
  67. The parental brain: Anatomization of 75 years of neuroscience 1951-2024.
  68. Bibliometric and LDA analysis of acute rejection in liver transplantation: Emerging trends, immunotherapy challenges, and the role of artificial intelligence.
  69. Mapping the landscape: Analysis of publication trends in forensic anthropology. Insights from Poland.
  70. An overview of reviews of breastfeeding barriers and facilitators: Analyzing global research trends and hotspots.
  71. Technology and Innovation Has Made Impact Factor Redundant-Better Alternatives Are Here to Thrive.
  72. Sensory Processing Measure and Sensory Integration Theory: A Scientometric and Narrative Synthesis.
  73. Mendelian randomization in the discovery of risk factors for autoimmune skin diseases: a bibliometric and visualized analysis.
  74. The impact of NIH funding and program reputation score on research output and residency matches in neurosurgery: A bibliometrics analysis.
  75. Impact of COVID-19 on Scholarly Outcomes of Pharmacy Practice Faculty by Gender and Academic Rank.
  76. Mapping intellectual structure and research hotspots of cancer studies in primary health care: A machine-learning-based analysis.
  77. Formalistic data and code availability policy in high-profile medical journals and pervasive policy-practice gaps in published articles: A meta-research study.
  78. Research publications and global manufacture of veterinary vaccines against avian influenza A (2019-2023).
  79. Track gender ratios in research to keep countries, institutions and publishers accountable.
  80. Research trends in pediatric diseases in North Korea: a scoping review of North Korean medical journals, 2006-2019.
  1. Discov Oncol. 2025 Mar 23. 16(1): 376
    Cardiotoxicity induced by chemotherapy and immunotherapy in cancer treatment: a bibliometric analysis.
    Xi Zhang, Yanfeng Xue, Mingyan Hao.
       OBJECTIVE: New chemotherapy and immunotherapy agents have revolutionized cancer treatment, significantly improving patient survival rates and quality of life while extending lifespans. However, these therapies often come with severe side effects, particularly cardiotoxicity. Over the past few decades, this field has seen steady growth. To better understand current trends, research hotspots, and collaborative networks in this area, a bibliometric analysis of relevant literature was conducted.
    METHODS: A comprehensive search was performed in the Web of Science for articles on cardiotoxicity induced by chemotherapy and immunotherapy in cancer treatment, published in SSCI and SCI-EXPANDED up to October 21, 2024. Using software tools such as GraphPad Prism, CiteSpace, and VOSviewer, we analyzed various parameters including publication year, countries, institutions, journals, authors, and references. Additionally, co-occurrence analyses, cooperation relationship assessments, co-citation networks, keyword maps, clustering analyses, and keyword emergence evaluations were conducted.
    RESULTS: As of October 21, 2024, a total of 5290 articles from 5674 institutions and 27,528 authors across 114 countries and regions were collected. The annual publication frequency and rate steadily increased. The United States emerge as the leading country in terms of publication volume, with the University of Texas System being the most prolific and frequently cited institution. "Breast Cancer Research and Treatment" was among the journals with revelant publications. Notable contributors included Ky bonnie and Thavendiranathan Paaladinesh, while Cardinale D achieved the highest average citation count per publication. Current research hotspots included echocardiography, trastuzumab, doxorubicin, radiotherapy, myocarditis, and 5-fluorouracil. The trend suggests that cardiotoxicity is expected to play an increasingly critical role in chemotherapy and immunotherapy for cancer treatment.
    CONCLUSION: This study provides a bibliometric visualization analysis of cardiotoxicity induced by chemotherapy and immunotherapy in the cancer treatment. It highlights current developments, collaborative efforts, and research hotspots within this field, offering essential scientific reference value for Cardio-Oncology.
    Keywords:  Bibliometrics; Cancer; Cardiotoxicity; Chemotherapy; CiteSpace; Immunotherapy; VOS viewers
    DOI:  https://doi.org/10.1007/s12672-025-02146-6
  2. Medicine (Baltimore). 2025 Mar 21. 104(12): e41895
    Twenty years of research on exercise-induced fatigue: A bibliometric analysis of hotspots, bursts, and research trends.
    Qiwen Xuan, Lele Huang, Wei Gu, Changquan Ling.
      Data from the Web of Science Core Collection (2004-2023) on "exercise-induced fatigue" were analyzed using bibliometric tools to explore research trends across countries, institutions, authors, journals, and keywords. The analysis was limited to "Article" and "Review" literature types. Among 4531 publications, the United States contributed the most articles (1005), followed by England (559) and China (516). The most influential institution was Universidade de São Paulo, while the most productive was Institut National de la Santé et de la Recherche Médicale with 103 papers. The European Journal of Applied Physiology ranked as the top journal with 233 articles. Millet Guillaume Y. emerged as the most prolific author, and Amann Markus was the most cited. Recent keyword trends showed a surge in terms like "physical activity" and "aerobic exercise," while "fatigue" and "exercise" remained dominant. Notable findings were observed in oncology, engineering, and multidisciplinary studies, indicating potential research trends. Oxidative stress was identified as the most commonly mentioned mechanism in exercise-induced fatigue studies. This bibliometric analysis highlights current research trends and gaps, suggesting that future studies should focus on understanding the mechanisms of exercise-induced fatigue, developing objective measurement criteria, and exploring strategies for its alleviation.
    DOI:  https://doi.org/10.1097/MD.0000000000041895
  3. Medicine (Baltimore). 2025 Mar 21. 104(12): e41907
    Global research trends and hotspots on imaging of bladder cancer: A bibliometric and visual analysis from 1981 to 2023.
    Zijian Gong, Zhixuan Liu, Jianghua Zhu, Zhen Zhao, Jia Qiu, Hongxin Ying, Yun Peng, Lianggen Gong, Yinquan Ye.
      There was currently no bibliometric analysis available regarding to bladder cancer (BCa) imaging. The aim of this study was to conduct a comprehensive bibliometric analysis of relevant literature on the imaging of BCa and elucidate global research hotspots and further trends in this field. All relevant literature on the imaging of BCa published between 1981 and 2023 were retrieved from the Web of Science Core Collection. VOSviewer, Bibliometrix, and Citespace were utilized for bibliometric analysis of publications, countries, authors, institutions, journals, references, and keywords. A total of 4462 articles were retrieved. The research in this field has been increasing consistently since 1981. The United States of America was the most productive country and most productive institutions were from it. Shariat SF was the most productive author with 36 articles and the author with the highest co-citations was Herr HW (472). Journal of Urology was the most productive journal and Frontiers in Oncology, Abdominal Radiology and Cancers exhibited heightened activity in recent years. A study by Siegel RL, published in CA-A Cancer Journal for Clinicians in 2019, had the highest number of co-citations. Further analysis of the keyword analysis and timeline view revealed that "radiomics," "deep learning," "multiparametric MRI," "VI-RADS," "muscle-invasive bladder cancer," "immunotherapy," and "long term outcome" were the most recent hotspots. In totally, in the period of 1981 to 2023 year, the USA occupies a critical position in the field of BCa imaging. It is anticipated that MRI-based imaging-reporting and data system and deep learning will be the research hotspots in the future.
    DOI:  https://doi.org/10.1097/MD.0000000000041907
  4. Medicine (Baltimore). 2025 Mar 21. 104(12): e41881
    The 100 most cited articles in androgenetic alopecia: A bibliometric analysis.
    Kinan Sawar, Louie Mekani, Alexander Kallabat, Dylan Kato, Geoffrey A Potts.
      Androgenetic alopecia (AGA) is a condition with a rapidly evolving research landscape. The expanding volume of AGA research necessitates synthesis to identify trends and gaps. Bibliometric analysis can be used to quantify the characteristics of a body of literature, and this technique has not been previously applied to AGA. We aimed to evaluate the bibliometric characteristics of the top 100 most cited AGA articles over the past 50 years. This includes the analysis of contributing authorship, institutional affiliation, journal representation, publication years, citation counts, country productivity, and funding sources, among other characteristics. We used the Web of Science to identify and characterize the 100 most cited AGA publications between 1975 and 2024. A secondary analysis was performed to identify and characterize the top 20 most cited AGA articles from 2020 to 2024. The top 100 articles amassed 24,289 citations. Authors from the United States contributed the most articles (n = 56). The University of Pennsylvania contributed the most articles (n = 11). Dr Elise A Olsen and Dr George Cotsarelis were the most frequent contributors. The Journal of the American Academy of Dermatology published the most number of articles. From 1975 to 2024, most studies primarily discussed pathophysiology (45%) and treatment (35%). However, from 2020 to 2024, 75% of the top articles focused on the treatment options. This bibliometric analysis provides an overview of influential AGA research over the last 50 years, highlighting shifting trends toward treatment optimization and emerging therapies.
    DOI:  https://doi.org/10.1097/MD.0000000000041881
  5. Front Cardiovasc Med. 2025 ;12 1483873
    Hotspots and frontiers in patent foramen ovale research: a bibliometric and visualization analysis from 2003 to 2023.
    Ying He, Zhaoxia Pu.
       Background: Patent foramen ovale (PFO) is among the most common congenital heart defects. Over the last two decades, the number of research publications on PFO has increased. This study aims to identify and describe the current state, hotspots, and emerging trends in PFO research over the previous 20 years using bibliometric analysis and visual mapping.
    Methods: The Web of Science Core Collection was searched for all publications on PFO research, which were then included in the study. CtieSpace, VOSviewer, and Excel software were used to visualize general information, publication output, countries/regions, authors, journals, influential papers, and keyword trends in this field.
    Results: This comprehensive analysis included 14,495 publications from 6,190 institutions across 115 countries. The United States dominated with the highest number of publications (2,407) and international collaborations. Mas JL made significant contributions to the PFO field, while Meier B emerged as a leading author, publishing 81 articles during the past 20 years. There were strong international collaborations among countries, institutions, and authors. Stroke, Circulation, and the New England Journal of Medicine were the most cited journals, with 13,124, 10,136, and 9,867 citations, respectively.
    Conclusions: This bibliometric study revealed that recent research frontiers primarily focused on the diagnosis and clinical management of patients with PFO. Future studies are expected to delve deeper into the biological mechanisms by which PFO contributes to stroke, the efficacy and limitations of PFO closure techniques, and the exploration of genetic variations associated with PFO and their roles in disease susceptibility.
    Keywords:  CiteSpace; VOSviewer; bibliometric study; cryptogenic stroke; echocardiography; patent foramen ovale
    DOI:  https://doi.org/10.3389/fcvm.2025.1483873
  6. Hum Vaccin Immunother. 2025 Dec;21(1): 2483558
    Uncovering global research frontiers in deubiquitinating enzymes and immunotherapy: A bibliometric study.
    Xia Chen, Yang Qin, Jinfeng Gan, Tangwen Wei, Xinyi Wei, Yaling Xiong, Zhichang Zhang, Bing Wei.
      Recently, immunotherapy has been a key therapeutic strategy for cancer. Deubiquitinating enzymes (DUBs), which are protein-modifying enzymes, have a crucial role in the pathogenesis of cancer, autoimmune diseases, and inflammation. DUBs influence the tumor immune microenvironment by regulating immune cell functions and key signaling pathways. Thus, the potential applications of DUBs in immunotherapy have piqued the interest of the scientific community. This study performed bibliometric analysis to comprehensively examine the research hotspots and trends in this field, providing theoretical foundations and guidance for future research. Studies associated with DUBs and immunotherapy conducted over a decade (2014 to 2024) were searched and extracted from Web of Science Collection database. The analysis was performed using CiteSpace, VOSviewer, and the Bibliometrix package in R software. Visualizations were generated for countries, institutions, authors, journals, references, and keyword co-occurrences. In total, 321 articles related to DUBs and immunotherapy were retrieved. The number of publications increased markedly since 2020. China had the highest number of publications, while the United States exerted the most influence in this field. Zhang Jinfang was the most influential author in this field. Zhejiang University was the institution with the highest number of publications. Nature was the most cited journal (807 total citations). Keyword analysis revealed that the primary research hotspots were expression, immunotherapy, ubiquitination, degradation, and cancer. This bibliometric analysis revealed the research trends and emerging frontiers in DUBs and immunotherapy, offering novel strategies for the application of DUBs in immunotherapy.
    Keywords:  Deubiquitinases; bibliometric analysis; deubiquitination; immunotherapy; tumor immune microenvironment
    DOI:  https://doi.org/10.1080/21645515.2025.2483558
  7. Front Aging Neurosci. 2025 ;17 1496252
    Global status and trends of exosomes in neurodegenerative diseases from 2014 to 2023: a bibliometric and visual analysis.
    Hao Wu, Yao-Lei Li, Pan-Miao Liu, Jian-Jun Yang.
       Background: Neurodegenerative diseases (NDs) are chronic and progressive conditions that significantly impact global public health. Recent years have highlighted exosomes as key mechanisms involved in these diseases. This study aims to visualize and analyze the structure and content of exosomes in NDs based on past research to identify new research ideas and directions. Through bibliometric analysis, we assess the current state of research on exosomes in the field of NDs worldwide over the past decade, highlighting significant findings, major research areas, and emerging trends.
    Methods: Publications on exosomes in NDs research were obtained from the Web of Science Core Collection (WOSCC) database. Eligible literature was analyzed using Bibliometric R, VOSviewer, and Citespace.
    Results: Between 2014 and 2023, 2,393 publications on exosomes in NDs were included in the analysis. The number of relevant publications has been increasing yearly, with China leading in international collaboration, followed by the United States. And China has the largest number of academic scholars as leading and corresponding authors in all the countries, known as the great research society and community. Notable institutions contributing to these publications include Nia, the University of San Francisco California, and Capital Medical University, which rank highly in both publication volume and citations. Dimitrios Kapogiannis is a pivotal figure in the author collaboration network, having produced the highest number of publications (Sato et al., 2011) and amassed 3,921 citations. The journal with the most published articles in this field is The International Journal of Molecular Sciences, which has published 131 articles and received 3,347 citations. A recent analysis of keyword clusters indicates that "Exosome-like liposomes," "Independent mechanisms," and "Therapeutic potential" are emerging research hotspots.
    Conclusion: This is the first bibliometric study to provide a comprehensive summary of the research trends and developments regarding exosomes in NDs studies. Future research in this area may explore the role of mesenchymal stromal cells, microRNAs (miRNAs), and targeted drug delivery systems to further investigate the underlying mechanisms and develop new therapeutics.
    Keywords:  Alzheimer’s disease; bibliometric; exosomes; neurodegenerative diseases; research frontiers
    DOI:  https://doi.org/10.3389/fnagi.2025.1496252
  8. Front Genet. 2025 ;16 1524360
    Bibliometric analysis of case-control studies on the association between HLA alleles and multiple sclerosis in adults.
    Enola Maer, Marjorie Maya Hubacher, Livia Livint Popa, Dana Marieta Fodor, Razvan Mircea Chereches, Dafin F Muresanu, Vitalie Vacaras, Maria Chiriac, Horea Vladi Matei, Nicu Catalin Draghici, Adrian Florea.
       Background: Multiple sclerosis (MS) is a complex autoimmune disease that affects the central nervous system (CNS) with genetic and environmental factors playing a significant role in its development and progression. One of the most important genetic factors associated with MS is the HLA gene complex. The relationship between HLA and MS has been the subject of numerous studies, but no bibliometric analysis of this research has been reported to date. Therefore, this study aimed to provide a comprehensive overview of the publication output, citation impact, collaboration patterns, and research topics related to HLA and MS.
    Methods: A bibliometric analysis of 488 studies published between 1988 and 2023 was conducted using RStudio, Tableau and VOSviewer software.
    Results: The results indicated an increasing trend in the number of publications and citations over time, with the highest productivity and impact coming from researchers in the United States, Italy and Sweden. The analysis also revealed collaboration networks among researchers and institutions, with the most common research topics being the association of HLA alleles with MS susceptibility, disease course, and treatment response. This study's limitations stem from the inherent biases associated with bibliometric analysis, including database and coverage bias, citation bias, and biases related to accessibility and open access. Additionally, the exclusion of non-English language articles represents a further limitation.
    Conclusion: Overall, this bibliometric analysis provides valuable insight into the research landscape of HLA and MS, highlighting the areas that have received the most attention and identifying potential avenues for future research.
    Keywords:  HLA; HLA-DRB1; MS; bibliometric analysis; genetic susceptibility; multiple sclerosis
    DOI:  https://doi.org/10.3389/fgene.2025.1524360
  9. Hum Vaccin Immunother. 2025 12;21(1): 2483022
    Fundamental knowledge and research regarding the role of immunity in triple-negative breast cancer from 2014-2024: A bibliometric analysis.
    Xudong Li, Chun Lou, He Ren, Lina Cui, Kexin Chen.
      Immunity has vital research value and promising applications in triple-negative breast cancer (TNBC). Nevertheless, few bibliometric analyses have systematically investigated this area. This study aimed to comprehensively review the collaboration and impact of countries, institutions, authors, and journals on the role of immunity in TNBC from a bibliometric perspective, evaluate the keyword co-occurrence of the knowledge structure, and identify hot trends and emerging topics. Articles and reviews related to immunity in TNBC were retrieved from the Web of Science core collection using subject search. A bibliometric study was conducted primarily using CiteSpace and VOSviewer. A total of 3,104 articles and reviews were included from January 1, 2014, through December 31, 2024. The number of articles on immunization in TNBC is rising. These publications are mainly from 415 institutions in 82 countries, led by China and the USA. Among these publications, Lajos Pusztai published the most papers, while Peter Schmid was co-cited the most. The most productive journals focused on molecular biology, biological immunology, and clinical medicine. Furthermore, co-citation analysis revealed that tumor microenvironment, biomarkers, and immune checkpoint inhibitors are current and developing research areas. The keywords "immunotherapy" and "nanoparticles" are also likely to be new trends and focal points for future research. This study adopted bibliometric and visualization methods to provide a comprehensive review of the research on immunization in TNBC. This article will help researchers better understand the dynamic evolution of the role of immunity in TNBC and identify areas for future research.
    Keywords:  Immunity; VOSviewer; bibliometric analysis; citespace; triple-negative breast cancer
    DOI:  https://doi.org/10.1080/21645515.2025.2483022
  10. Front Med (Lausanne). 2025 ;12 1539386
    Research hotspots and trends of skin barrier in atopic dermatitis in the past 24-year: a bibliometric analysis.
    Fangchang Huang, Xin Zhu, Xinglong Liang.
       Background: Atopic dermatitis (AD) is a chronic, pruritic, inflammatory skin condition that imposes significant psychological and economic burdens on patients due to its recurring nature. Its etiology is multifactorial, involving interactions between genetic predispositions and environmental factors. The skin barrier serves as both a mechanical and immunological defense, and its structural damage and functional impairments significantly contribute to the pathogenesis of AD. This study aims to explore the future prospects and developmental trends of the skin barrier in the context of AD through a bibliometric analysis.
    Objective: To analyze the research status, hot spots and development trend of skin barrier in AD.
    Methods: Relevant studies were extracted from the Web of Science database and screened by researchers, with bibliometric analysis conducted using VOSviewer, CiteSpace, and other tools.
    Results: A total of 4,227 publications were identified over a 24-year research period. The United States is the leading contributor, with 1,263 publications, and demonstrates extensive collaboration with numerous countries. The journal with the highest number of publications is the Journal of Allergy and Clinical Immunology. The most prolific institutions is the University of California, San Francisco. Recent years have seen high citation intensity for keywords such as "dupilumab," "barrier dysfunction," and "gut microbiota".
    Conclusion: The mechanism of the skin barrier in AD remains an area requiring ongoing research and analysis. Although significant progress has been achieved, future research will benefit from advancements in technology.
    Keywords:  CiteSpace; VOSviewer; atopic dermatitis; bibliometric analysis; skin barrier
    DOI:  https://doi.org/10.3389/fmed.2025.1539386
  11. Cancer Biol Ther. 2025 Dec;26(1): 2484825
    Bibliometric analysis of autophagy in the diagnosis and treatment of osteosarcoma: a bibliometric analysis (2007-2023).
    Min Zhu, Wei Xiang, Zhoujun Zhu, Bingjie Nie, Xinyue Zhen, Chen Chen, Tianhai Wang.
      Osteosarcoma is the most common primary bone tumor in children and adolescents. Its pathogenesis is complex and poses difficulties in treatment. Autophagy is a cell biological process that plays a crucial role in the mechanistic study and treatment of osteosarcoma. The objective of this study is to evaluate the past research progress from 2007 to 2023 and visualize the key research directions through bibliometric methods. Relevant publications published from the start of 2007 to the end of 2023 were searched and screened in the Web of Science Core Collection. They were analyzed and visualized using CiteSpace and the Bibliometric online analysis platform in terms of country, institution, author, journal, cited references, and keywords. In total, 619 publications from 522 journals with 682 authors from 42 countries were screened. The country with the highest number of publications is China (n = 445, 71.890%), followed by the United States (n = 60, 9.693%). The research institution with the highest number of publications is Shanghai Jiao Tong University (n = 42, 6.785%). The author with the highest number of publications is Cai, Zhengdong (n = 7), while the most cited author is Mizushimma N (n = 93). Among many journals, AUTOPHAGY has the most citations (n = 342), while CANCER LETT shows the greatest centrality (Centrality = 0.05). "Autophagy" is the most cited keyword (n = 177), and the keyword with the largest burst intensity is "cancer cells" (Strength = 6.27), which lasted from 2011 to 2014. China is a major contributor to autophagy research in the field of osteosarcoma, followed by the United States. All publications are in high-quality journals. "Autophagy" is a hot research topic in this field.
    Keywords:  Autophagy; bibliometric; citeSpace; osteosarcoma; visualization
    DOI:  https://doi.org/10.1080/15384047.2025.2484825
  12. Pathogens. 2025 Mar 15. pii: 289. [Epub ahead of print]14(3):
    A Bibliometric Analysis of HPV-Positive Oropharyngeal Squamous Cell Carcinoma from 2000 to 2023.
    Yingying Cui, Wei Li, Binbin Li.
      Human-papillomavirus-positive oropharyngeal squamous cell carcinoma (HPV-positive OPSCC) is a distinct disease characterized by unique clinical and molecular features compared to HPV-negative OPSCC. A comprehensive bibliometric analysis of HPV-positive OPSCC research was conducted in this study to identify key trends, research hotspots, and emerging frontiers in the field. Data were retrieved from the Web of Science Core Collection database. The distributions of contributors, including countries, institutions, authors, journals, and cooperative networks related to HPV-positive OPSCC, were analyzed and visualized using VOSviewer 1.6.20, CiteSpace 6.3.R1, and the R package Bibliometrix 4.0.0. In addition, the most influential publications and high-frequency keywords were identified and analyzed to discern key topics in this field. A total of 3895 articles and reviews on HPV-positive OPSCC were identified, involving 106 countries, 620 journals, and 18949 authors. The main contributors include the USA (1908 publications), Johns Hopkins University (310 publications), the journal Head and Neck (320 publications), and Erich M. Sturgis (94 publications). The top three keywords are "survival", "radiotherapy", and "p16". There has been a steadily increasing research interest in HPV-positive OPSCC over the last 23 years. Current studies focus on diagnosis, treatment strategies, prognosis, recurrence, and disease surveillance. This bibliometric analysis highlights key contributors and emerging themes, offering insights for future research directions.
    Keywords:  bibliometric analysis; human papillomavirus; oropharyngeal squamous cell carcinoma
    DOI:  https://doi.org/10.3390/pathogens14030289
  13. J Int Soc Prev Community Dent. 2025 Jan-Feb;15(1):15(1): 1-15
    Top 100 Most-Cited Papers on Temporomandibular Disorders in Children: A Bibliometric Analysis.
    Adriana A De Stefano, Gioia Longarini, Martina Horodynski, Gabriella Galluccio.
       Aim: The aim of this bibliometric analysis was to analyze the top 100 most-cited articles on temporomandibular disorders (TMDs) in children and to identify the most-cited authors, journals, institutions, and countries.
    Materials and Methods: The publication search was performed using The Clarivate Analytics Web of Science Core Collection in May 2023. The terms "TMD" and "Children" were used in the search strategy. The time range considered extends from 1985 to the date of data extraction. No limitations were applied concerning language. For pertinent statistical computation, the finalized facts were transferred into the R environment (R package Bibliometrix version 3.1) and generated relevant graphics and collaborative network mapping. Word co-occurrence in 100 articles was visualized using VOSviewer software.
    Results: The 100 most influential manuscripts were published between 1991 and 2021. In the years considered, 6987 citations were included in the top 100 papers that were taken into consideration, with an annual mean citation of 215.63. Top contributors to the field were Sweden, the USA, and Brazil. The most-cited studies were produced by the US University of Washington (n = 11; 1158 citations), the Swedish University of Gothenburg (n = 10; 950 citations), and the Swedish University of Malmo (n = 9; 519 citations). List T was the most productive author (801 citations). The Journal of Oral Rehabilitation is the most cited among the 100 articles (801 times).
    Conclusion: To determine the important writers, nations, organizations, and journals in the subject of TMD in children, this study examined the top 100 cited articles in the field with the greatest number of citations. Additionally, the study's hotspots, prospective trends, and state of research were given in TMD in a growing population.
    Keywords:  Adolescent; bibliometrics; children; citation; temporomandibular disorders
    DOI:  https://doi.org/10.4103/jispcd.jispcd_118_24
  14. Aesthetic Plast Surg. 2025 Mar 28.
    Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): A Bibliometric Analysis of Publication Trends.
    Edoardo Caimi, Stefano Vaccari, Valeriano Vinci.
       BACKGROUND: Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) has become a significant concern in plastic surgery, particularly following the 2019 recall of Allergan macro-textured implants. While research has addressed its epidemiology and management, a comprehensive analysis of global publication trends is lacking. This study provides a bibliometric evaluation of the scientific literature on BIA-ALCL, identifying key contributors, research trends, and emerging areas of interest.
    METHODS: A bibliometric analysis was conducted using the Web of Science Core Collection to retrieve English-languagepublications on BIA-ALCL from 1995 to 2024. Bibliometric indicators, including publication trends, authorship, country contributions, institutional affiliations, and citation impact, were analyzed. VOSviewer 1.6.20 was used for keyword co-occurrence and cluster analyses.
    RESULTS: A total of 1,148 publications were identified, with a sharp increase after 2018. The United States contributed the most research (43.81%), followed by Italy, England, Australia, and Brazil. Cluster analysis revealed four thematic areas: clinical presentation and risk factors, diagnostic strategies, epidemiology and treatment, and etiological hypotheses. The most cited article was Keech et al. (1997), documenting an early case of BIA-ALCL.
    CONCLUSIONS: This bibliometric analysis highlights the increasing research focus on implant surface characterization, disease etiology, and patient management. These findings provide valuable insights into the evolution of BIA-ALCL literature and may inform future research and clinical decision-making in plastic surgery.
    LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors   www.springer.com/00266 .
    Keywords:  BIA-ALCL; Bibliometric analysis; Future research; Publication trends
    DOI:  https://doi.org/10.1007/s00266-025-04845-5
  15. Neurosurg Rev. 2025 Mar 28. 48(1): 336
    A bibliometric analysis of blunt cerebrovascular injury: the top 50 most instrumental articles.
    Jennifer Shields, Frank De Stefano, Lane Fry, Koji Ebersole, Jeremy Peterson.
       OBJECTIVE: Blunt cerebrovascular injury (BCVI) is a collective term describing blunt-force trauma involving the carotid and/or vertebral arteries. As awareness, screening protocols, and diagnostic modalities have advanced over recent decades, reported incidence has risen accordingly. This bibliometric review examines the most highly cited literature on BCVI, spotlighting key academic trends, influential authors, and journals that have shaped our current understanding.
    METHODS: The Scopus database was queried for BCVI-related articles published through June 2024 with titles, abstracts, and/or keywords containing the terms "BCVI" OR "blunt cerebrovascular injury" OR " blunt carotid artery injury" OR "blunt carotid artery trauma" OR "traumatic carotid artery dissection" OR "blunt vertebral artery injury" OR "blunt vertebral artery trauma" OR "traumatic vertebral artery dissection." Results were organized by descending citation count and followed by citations per year. The top 50 most-cited articles were selected for analysis. Additional data collected included document titles, publication year, authors, specialty of the first author, affiliations, country of origin, and publishing journal.
    RESULTS: This study retrieved 426 BCVI-related articles published since 1974. The top 50, published between 1974 and 2018, garnered 6,760 citations, with an average of 135.2 citations per article, and a mean self-citation rate of 8.83%.
    CONCLUSIONS: This bibliometric analysis maps the academic landscape of BCVI, presenting valuable insights into its evolution and the pivotal studies that have informed our knowledge and clinical practice thus far. It serves as a foundation for future research directions and clinical advancements, aimed at enhancing patient outcomes in the face of blunt cerebrovascular trauma.
    CLINICAL TRIAL NUMBER: Not applicable.
    Keywords:  Bibliometric analysis; Blunt cerebrovascular injury; Neurosurgery; Non-penetrating trauma
    DOI:  https://doi.org/10.1007/s10143-025-03487-0
  16. Public Health Nurs. 2025 Mar 24.
    A Bibliometric Analysis of Global Research Trends in Elderly Population Diseases.
    Hao Wu, Zining Zhao.
       BACKGROUND: The global population is undergoing rapid aging, resulting in a significant increase in scientific publications addressing diseases and health challenges in the elderly population.
    METHODS: A literature search for publications on diseases in the elderly population was conducted using PubMed, Web of Science Core Collection, and Embase from January 1, 2000, to January 1, 2024. Bibliometric and visualization analyses were performed using VOSviewer software.
    RESULTS: A total of 16,862 publications were retrieved, with a notable increase in publication output after 2016. The United States led in both publication numbers (n = 6502, 38.56%) and citations (342,586), underscoring its substantial contribution to this field. Influential institutions such as the University of Pittsburgh and Karolinska Institute played key roles. Keywords analysis identified 631 meaningful topics, classified into five clusters, with research hotspots focusing on cardiovascular diseases, dementia, frailty, and quality of life. Emerging keywords in public health and nursing, such as "mild cognitive impairment," "multimorbidity," and "frailty," have been frequently highlighted in recent studies, indicating critical priorities for future research in elderly care.
    CONCLUSIONS: This study provides a comprehensive bibliometric and visualization analysis of global research trends on diseases in the elderly population. It highlights key research areas and offers valuable insights to guide future directions in public health and nursing strategies, emphasizing the importance of interdisciplinary approaches to address aging-related challenges.
    Keywords:  Embase; PubMed; VOSviewer; Web of Science; diseases; elderly population
    DOI:  https://doi.org/10.1111/phn.13557
  17. J Patient Saf. 2025 Mar 26.
    Patient Safety Culture Research: A Bibliometric Analysis From 2001 to 2023.
    Tianli Huang, Yan Wu.
       OBJECTIVES: To perform a bibliometric analysis of research on patient safety culture from 2001 to 2023.
    METHODS: Retrieve the SSCI and SCIE data in the Web of Science Core Collection with the title "Patient Safety Culture" from January 1, 2001, to December 31, 2023. HistCite, Bibliometrix Package, VOSviewer, and Jshare were used to conduct bibliometric analyses. The analysis contents included publications, distribution of countries/regions, core journals, organizations, the evolution of keywords over the years, future trends of the field, author contributions, and citation analysis.
    RESULTS: A total of 595 articles authored by 2383 individuals from 1048 different sources were collected. The United States emerged as the most prolific country (N=142), while Westat Corporation was the leading institution (N=11). The number of papers issued by developing and advanced economies is gradually balanced after 2022. The top researchers were Wagner C, Hammer A, and Hasegawa T. The analysis identified 1427 keywords, with the most frequently used being "climate," "health care," "adverse events," "nurses," and "quality." It was noted that trending topics such as "healthcare providers," "work environment," and "high-reliability" have gained traction recently, while earlier years saw a focus on "climate," "care," "healthcare," "perceptions," and "nurses."
    CONCLUSIONS: Patient safety culture research is gaining increasing attention in the coming years, especially in developing countries. Future research should prioritize the "work environment" and "climate" to enhance patient safety culture, particularly addressing the "barriers" to improving "management" and "communication."
    DOI:  https://doi.org/10.1097/PTS.0000000000001338
  18. Naunyn Schmiedebergs Arch Pharmacol. 2025 Mar 25.
    Bibliometric and visual analysis of drug-specific immunotherapy from 1990 to 2024.
    Zhengjiu Cui, Xiaorui Chen, Siming Zhai, Yuanyuan Wang, Chanchan Hu, Bin Yuan.
      Specific immunotherapy (SIT) is key in allergic diseases, tumor immunity, and autoimmune regulation. In recent years, the mechanism of action of drugs in SIT has attracted much attention, including the induction of hypersensitivity responses and modulation of immune tolerance. However, scientific challenges remain regarding their mechanism of action and optimization strategies. Studies on pharmacological SIT have been accumulated in the past, and there is an urgent need for bibliometric analyses to review and prospect these results for future academic development. Strict search criteria were developed to screen and download literature information from the Web of Science Core Collection. Six elements of the included literature were analyzed and visualized using Citespace, VOSviewer software, and the Bibliometrix package. A total of 682 publications related to the drug SIT were included in this study. The growth trend in the number of publications is evident and entering a new phase with great potential for the future, with the highest total number of citations in 1998. The countries and institutions with the most publications were the USA and the University of Genoa. The author who contributed the most to the field was Incorvaia, Cristoforo. Moreover, Bousquet J was the most influential author. Allergy was considered the leading core source journal, and the Journal of Allergy and Clinical Immunology is the most influential. The reference with the highest outbreak intensity is Roberts G, 2018, Allergy, V73, P765, https://doi.org/10.1111/all.13317 . The analysis of the keywords by the various metrics shows that the research hotspot is the tumor-associated SIT, the cutting-edge topic is the mechanism of action of the drug AIT, and the respiratory SIT application is the cutting-edge hot issue. Drug SIT has made good progress with the joint participation of global research institutions, scientists, and various journals. However, cooperation and communication are weak, and it is necessary to build a new cooperation mode to promote the globalization of research results. We have found the research hotspots and cutting-edge issues in this field, which will guide us to make breakthroughs in a more precise direction and play the important role of drug safety in safeguarding human life and health.
    Keywords:  Bibliometric analysis; Cooperation; Drug; Specific immunotherapy; Visual analytics; Web of Science
    DOI:  https://doi.org/10.1007/s00210-025-04073-3
  19. J Ophthalmic Inflamm Infect. 2025 Mar 25. 15(1): 31
    Uveitis output in high-impact clinical ophthalmology journals: a bibliometric analysis.
    Baotram V Nguyen, Priyanka Bhatnagar, Daniel C Lee, Meghan K Berkenstock.
       BACKGROUND: Despite uveitis subspecialty workforce shortages, uveitis specialists remain engaged in research. This study examines the relationship between the proportions of uveitis-focused articles in high-impact ophthalmology journals and fellowship-trained uveitis specialists on their editorial boards.
    METHODS: A bibliometric analysis was conducted on articles published from 2014 to 2023 in the five highest-impact ophthalmology journals: Ophthalmology, JAMA Ophthalmology, British Journal of Ophthalmology (BJO), American Journal of Ophthalmology (AJO), and Investigative Ophthalmology and Visual Science (IOVS). Editorial board members with uveitis or ocular immunology fellowships were identified from public domain sources. Articles were screened using uveitis MeSH terms. Data analysis was performed using STATA to assess the relationship between the proportions of uveitis-focused articles and uveitis-trained editors.
    RESULTS: From 2014 to 2023, 3.57% (575/16,093) of articles published in the five journals were uveitis-focused. The proportion of uveitis-focused articles ranged from 1.74% in IOVS to 5.89% in AJO. On average, fellowship-trained uveitis specialists comprised 5.28% of editorial board members annually. There were positive correlations between the proportions of uveitis-focused articles and uveitis-trained editors annually (r = 0.6799, p < 0.00005) and over the 10-year period (r = 0.2675, p < 0.00005). No significant correlation was observed within individual journals.
    CONCLUSIONS: Uveitis research remains underrepresented in high-impact ophthalmology journals despite research productivity in the field. While a positive correlation between uveitis-trained editors and uveitis-focused articles was found across all journals, this trend did not hold within individual journals. Enhancing uveitis research visibility in high-impact journals is essential to advancing clinical knowledge, improving patient outcomes, and inspiring ophthalmologists to enter this underserved subspecialty.
    Keywords:  Impact factor; Ocular immunology; Research output; Uveitis; Uveitis specialists
    DOI:  https://doi.org/10.1186/s12348-025-00490-w
  20. Discov Oncol. 2025 Mar 26. 16(1): 398
    Global trends in esophageal cancer and metabolic syndrome research: bibliometric analysis and visualization from 1995 to 2024.
    Peng-Yu Che, Chun-Jian Zuo, Jie Tian.
       PURPOSE: Metabolic syndrome (MetS) plays a key role in the progression of esophageal cancer (EC), yet few studies have comprehensively explored research trends on this topic. To fill this gap, this study analyzes global research developments, hotspots, and collaborations related to MetS and EC.
    METHODS: A total of 1008 publications from 1995 to 2024 were analyzed using bibliometric tools like VOSviewer, CiteSpace, and the R package 'bibliometrix', drawing from the Web of Science Core Collection.
    RESULTS: The analysis includes contributions from 5,183 researchers at 1500 institutions across 85 countries, with publications appearing in 411 journals. The United States, China, and the United Kingdom are leading in both publication volume and research impact. Karolinska Institutet emerged as a prominent contributor to this body of work. Key journals include the Diseases of the Esophagus and Gastroenterology. Main areas cover metabolic factors, metabolic surgery, adipokines, lifestyle risk factors, cirrhosis & portal hypertension. Emerging trends focus on "metabolic syndrome and EC risk", "inflammation and adipokines", "bariatric surgery and EC prevention", "post-surgical outcomes", "early detection strategies".
    CONCLUSION: As the first comprehensive bibliometric study on MetS and EC, this research highlights metabolism-related factors driving EC progression. Future research should focus on clarifying MetS-EC mechanisms and developing prevention and treatment strategies.
    Keywords:  Bibliometric analysis; Esophageal cancer; Main themes; Metabolic syndrome; Research trends
    DOI:  https://doi.org/10.1007/s12672-025-02181-3
  21. Genes (Basel). 2025 Mar 13. pii: 336. [Epub ahead of print]16(3):
    Centenary Progress on Orchidaceae Research: A Bibliometric Analysis.
    Yonglu Wei, Jie Li, Jianpeng Jin, Jie Gao, Qi Xie, Chuqiao Lu, Genfa Zhu, Fengxi Yang.
       BACKGROUND: Research on orchids has experienced substantial growth since the early 20th century, reflecting their ecological and evolutionary significance.
    METHODS: This paper provides a comprehensive bibliometric analysis of orchid-related literature published between 1902 and 2024, based on data retrieved from the Web of Science Core Collection™ (WoS).
    RESULTS: The primary goal is to assess the global research landscape of orchids by identifying key authors, institutions, and journals, as well as major research themes in the field. A thorough analysis of publication trends, citation frequencies, and keyword co-occurrence networks was conducted to uncover significant research hotspots. The findings indicate that orchid research has evolved from foundational topics such as taxonomy and classification to more intricate subjects, including conservation strategies, orchid-pollinator dynamics, and the role of orchids in ecosystem functions. Additionally, biotechnology-related research is emerging as a dominant trend. This study also highlights that China has the highest publication output, while collaboration between the United States and Europe continues to grow. The co-word analysis of keywords suggests that future research is likely to continue to focus on orchid conservation, the impacts of climate change, pollination biology, and symbiotic relationships with mycorrhizal fungi.
    CONCLUSIONS: This review offers valuable insights for researchers and conservationists, helping to identify future research priorities and strategies for the preservation and sustainable use of orchids.
    Keywords:  Orchidaceae; bibliometric analysis; co-word analysis; phylogenetics; web of science
    DOI:  https://doi.org/10.3390/genes16030336
  22. Skin Res Technol. 2025 Jan;31(1): e70165
    RETRACTION: A Bibliometric Analysis of Global Research on Microbial Immune Microenvironment in Melanoma From 2012 to 2022.
      
    DOI:  https://doi.org/10.1111/srt.70165
  23. Digit Health. 2025 Jan-Dec;11:11 20552076251324446
    Artificial intelligence in obstructive sleep apnea: A bibliometric analysis.
    Xing An, Jie Zhou, Qiang Xu, Zhihui Zhao, Weihong Li.
       Objective: To conduct a bibliometric analysis using VOSviewer and Citespace to explore the current applications, trends, and future directions of artificial intelligence (AI) in obstructive sleep apnea (OSA).
    Methods: On 13 September 2024, a computer search was conducted on the Web of Science Core Collection dataset published between 1 January 2011, and 30 August 2024, to identify literature related to the application of AI in OSA. Visualization analysis was performed on countries, institutions, journal sources, authors, co-cited authors, citations, and keywords using Vosviewer and Citespace, and descriptive analysis tables were created by using Microsoft Excel 2021 software.
    Results: A total of 867 articles were included in this study. The number of publications was low and stable from 2011 to 2016, with a significant increase after 2017. China had the highest number of publications. Alvarez, Daniel, and Hornero, Roberto were the two most prolific authors. Universidad de Valladolid and the IEEE Journal of Biomedical and Health Informatics were the most productive institution and journal, respectively. The top three authors in terms of co-citation frequency are Hassan, Ar, Young, T, and Vicini, C. "Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis" was cited the most frequently. Keywords such as "OSA," "machine learning," "Electrocardiography," and "deep learning" were dominant.
    Conclusion: AI's application in OSA research is expanding. This study indicates that AI, particularly deep learning, will continue to be a key research area, focusing on diagnosis, identification, personalized treatment, prognosis assessment, telemedicine, and management. Future efforts should enhance international cooperation and interdisciplinary communication to maximize the potential of AI in advancing OSA research, comprehensively empowering sleep health, bringing more precise, convenient, and personalized medical services to patients and ushering in a new era of sleep health.
    Keywords:  Artificial intelligence; bibliometric analysis; deep learning; machine learning; obstructive sleep apnea
    DOI:  https://doi.org/10.1177/20552076251324446
  24. Ophthalmic Plast Reconstr Surg. 2025 Mar 25.
    Evaluation of Research Productivity Among Academic Oculoplastic Surgeons Using the Relative Citation Ratio.
    Matthew N Henderson, Lucy S Guan, Oliver Guyer, Catherine J Hwang, Julian D Perry.
       PURPOSE: To evaluate research productivity among oculoplastic surgeons and provide relative citation ratio (RCR) benchmark data for the field.
    METHODS: In this cross-sectional bibliometric analysis, fellowship-trained academic oculoplastic surgeons at Accreditation Council for Graduate Medical Education-accredited institutions were individually indexed using the National Institutes of Health iCite database. Publication count, mean RCR (mRCR) score, and weighted RCR score were collected for each author between February and May 2023 and included PubMed-listed articles from 1980 to 2022. Data were compared by gender, career duration, academic rank, and acquisition of a doctor of philosophy.
    RESULTS: Two hundred ninety-nine academic oculoplastic surgeons from 113 institutions were indexed. These physicians produced highly impactful research with a median publication count of 20 (interquartile range, 8-45), median mRCR of 0.91 (interquartile range, 0.65-1.24), and median weighted RCR of 16.27 (interquartile range, 5.61-41.10). Academic rank and career duration were associated with increased publication count, mRCR, and weighted RCR. Weighted RCR scores were greater among male faculty, but no differences were observed between genders for publication count or mRCR score. Female faculties were underrepresented in more senior academic ranks and earlier career start years.
    CONCLUSIONS: Current academic oculoplastic surgeons have comparable mRCR values relative to the National Institutes of Health-standard RCR value of 1. These benchmark data serve as a more accurate gauge of research impact within the oculoplastic surgery community and can be used to inform self, institutional, and departmental evaluations. In addition, the mRCR may provide an accurate metric for quantifying research productivity among historically underrepresented groups that are disadvantaged by time-dependent factors such as the number of publications.
    DOI:  https://doi.org/10.1097/IOP.0000000000002940
  25. Microorganisms. 2025 Mar 17. pii: 673. [Epub ahead of print]13(3):
    Research Status and Trends of Gut Microbiota and Intestinal Diseases Based on Bibliometrics.
    Xiao Sun, Jiancheng Zhai.
      Gut microbiota plays an important role in gut health, and its dysbiosis is closely related to the pathogenesis of various intestinal diseases. The field of gut microbiota and intestinal diseases has not yet been systematically quantified through bibliometric methods. This study conducted bibliometric analysis to delineate the evolution of research on gut microbiota and intestinal diseases. Data were sourced from the Web of Science Core Collection database from 2009 to 2023 and were scientometrically analyzed using CiteSpace. We have found that the number of annual publications has been steadily increasing and showing an upward trend. China and the Chinese Academy of Sciences are the country and institution with the most contributions, respectively. Frontiers in Microbiology and Nutrients are the journals with the most publications, while Plos One and Nature are the journals with the most citations. The field has shifted from focusing on traditional descriptive analysis of gut microbiota composition to exploring the causal relationship between gut microbiota and intestinal diseases. The research hotspots and trends mainly include the correlation between specific intestinal diseases and gut microbiota diversity, the mechanism of gut microbiota involvement in intestinal diseases, the exploration of important gut microbiota related to intestinal diseases, and the relationship between gut microbiota and human gut health. This study provides a comprehensive knowledge map of gut microbiota and intestinal diseases, highlights key research areas, and outlines potential future directions.
    Keywords:  bibliometric; gut microbiota; hotspots; intestinal diseases; trends
    DOI:  https://doi.org/10.3390/microorganisms13030673
  26. Vet Med Sci. 2025 May;11(3): e70258
    Comprehensive Global Analysis of Future Trends in Artificial Intelligence-Assisted Veterinary Medicine.
    Sadi Elasan, Osman Yilmaz.
       BACKGROUND: This study conducts a bibliometric analysis of global trends in 'artificial intelligence studies in veterinary medicine'. The analysis aims to summarise the publications of researchers from various disciplines related to artificial intelligence in veterinary medicine, thereby predicting future trends of AI in this field. The primary objective of the study is to investigate publications pertaining to artificial intelligence in veterinary medicine worldwide and to analyse trends and future developments in this area.
    METHODS: This bibliometric study examines artificial intelligence research in veterinary medicine conducted worldwide from 1990 to 2024. To achieve this, a search using the keywords 'artificial intelligence' and 'veterinary medicine' was performed in the Web of Science (WOS) database, resulting in the identification of 1497 studies. After excluding irrelevant publications and those outside the scope of articles, a total of 1400 articles were included in the analysis. The data collection process utilised titles, author names, publication years, journal names, and citation counts. All textual data were analysed using VOSviewer software to ensure accuracy and reliability. In this study, analyses conducted through text mining and data visualisation techniques (e.g., bubble maps) facilitated a clearer understanding of the results.
    RESULTS: This study presents information about 1400 articles obtained from the WOS database and a total of 44,700 citations for these articles. The average number of citations per article is 32, with an H-index of 74. A rapid increase in both the number of articles and citations has been observed since 2019. The majority of the articles (30%) were published in the fields of veterinary sciences, artificial intelligence, and computer sciences. The United States, Taiwan and the United Kingdom are the leading countries, accounting for 84% of the published articles in this field. Additionally, 12% of the articles were published in the area of veterinary sciences, and 85% of the articles fall within the SCI-Expanded category.
    CONCLUSIONS: The findings of our study indicate that there are numerous active researchers in the field of artificial intelligence in veterinary medicine and that research in this area is steadily increasing. This bibliometric analysis highlights global trends and significant works in artificial intelligence within veterinary medicine, providing valuable insights into the future directions of research in this field. As the analysis aims solely to identify trends and patterns in the literature, it does not intend to evaluate the applicability of the subject matter.
    HIGHLIGHTS: Analysis of Global Trends: This study comprehensively analyses the global trends and effects of research on artificial intelligence in veterinary medicine. In this context, it contributes to the identification of significant changes and developments in the literature. Rapidly Spreading Research: Research on artificial intelligence in veterinary medicine has rapidly expanded in recent years, and this trend is expected to continue. The increase in studies indicates an expansion of knowledge and applications in this field. Diagnostic and Therapeutic Tools: Artificial intelligence research serves as a valuable tool in veterinary medicine, particularly in improving the diagnosis and treatment processes for various diseases. This contributes to the development of more effective methods for animal health and care. Increasing Number of Publications: The number of studies on artificial intelligence in veterinary medicine worldwide is increasing each year. Notably, after the Covid-19 pandemic, there has been a significant rise in publications in this field. This indicates that the importance of artificial intelligence in both human and animal health has grown, with the pandemic intensifying research interest. Prominent Countries: Among the countries examined in the study, the United States, Taiwan, England, and Germany emerged as leaders in this research area. Conversely, it was noted that some countries have very few or no academic publications in the field of artificial intelligence in veterinary medicine.
    Keywords:  animal health; artificial intelligence; global trends; veterinary medicine
    DOI:  https://doi.org/10.1002/vms3.70258
  27. JMIR Med Educ. 2025 Mar 26. 11 e71844
    Knowledge Mapping and Global Trends in Simulation in Medical Education: Bibliometric and Visual Analysis.
    Hongjun Ba, Lili Zhang, Xiufang He, Shujuan Li.
       BACKGROUND: With the increasing recognition of the importance of simulation-based teaching in medical education, research in this field has developed rapidly. To comprehensively understand the research dynamics and trends in this area, we conducted an analysis of knowledge mapping and global trends.
    OBJECTIVE: This study aims to reveal the research hotspots and development trends in the field of simulation-based teaching in medical education from 2004 to 2024 through bibliometric and visualization analyses.
    METHODS: Using CiteSpace and VOSviewer, we conducted bibliometric and visualization analyses of 6743 articles related to simulation-based teaching in medical education, published in core journals from 2004 to 2024. The analysis included publication trends, contributions by countries and institutions, author contributions, keyword co-occurrence and clustering, and keyword bursts.
    RESULTS: From 2004 to 2008, the number of articles published annually did not exceed 100. However, starting from 2009, the number increased year by year, reaching a peak of 850 articles in 2024, indicating rapid development in this research field. The United States, Canada, the United Kingdom, Australia, and China published the most articles. Harvard University emerged as a research hub with 1799 collaborative links, although the overall collaboration density was low. Among the 6743 core journal articles, a total of 858 authors were involved, with Lars Konge and Adam Dubrowski being the most prolific. However, collaboration density was low, and the collaboration network was relatively dispersed. A total of 812 common keywords were identified, forming 4189 links. The keywords "medical education," "education," and "simulation" had the highest frequency of occurrence. Cluster analysis indicated that "cardiopulmonary resuscitation" and "surgical education" were major research hotspots. From 2004 to 2024, a total of 20 burst keywords were identified, among which "patient simulation," "randomized controlled trial," "clinical competence," and "deliberate practice" had high burst strength. In recent years, "application of simulation in medical education," "3D printing," "augmented reality," and "simulation training" have become research frontiers.
    CONCLUSIONS: Research on the application of simulation-based teaching in medical education has become a hotspot, with expanding research areas and hotspots. Future research should strengthen interinstitutional collaboration and focus on the application of emerging technologies in simulation-based teaching.
    Keywords:  bibliometrics; knowledge mapping; medical education; simulation-based teaching; visualization analysis
    DOI:  https://doi.org/10.2196/71844
  28. Hosp Pharm. 2025 Mar 20. 00185787251326821
    Four Decades of Progress: Evaluating Saudi Arabia's Research Publications in Pharmaceutical Sciences.
    Dileep K Rohra, Ismail Memon.
      Objectives: This study aims to analyze the quantity and quality of pharmaceutical science publications originating from Saudi Arabia and compare research publications retrieved from Scopus over the past 40 years (1980-2019). Methods: Data was collected from Scopus, with each publication assigned a unique identifier. Information such as the journal's name, year of publication, and publication type were recorded. The Journal Impact Factor (JIF) for the year 2018, obtained from ISI Web of Science, was used for all publications. The mean impact factor (MIF) for each year was calculated by dividing the cumulative IF by the total number of publications in that year. All data was entered into Microsoft Excel and analyzed using numbers, means, and percentages. Results: A total of 12 299 papers were published from Saudi Arabia in the field of pharmaceutical sciences. A modest growth trend in publication was observed from 1980 to 2008. However, starting in 2009, there was a notable increase in annual publication counts, reaching 1400 by 2016, and maintaining a range of 1200 to 1400 annually until 2019. A highly statistically significant upward trajectory in the JIF was observed from 1980 to 2018, with annual variations. The SCImago Journal Rank also exhibited a similar pattern of increased research growth. Conclusion: This study indicates a consistent growth in both the quantity of publications and the presence in quality journals indexed with Scopus published in the field of pharmaceutical sciences from Saudi Arabia.
    Keywords:  SJR; Saudi Arabia; Scopus; journal impact factor; pharmaceutical research; publications
    DOI:  https://doi.org/10.1177/00185787251326821
  29. Front Med (Lausanne). 2025 ;12 1529218
    The current state and development trends of frailty research in diabetic patients: a bibliometric analysis.
    Ziqi Xu, Rui Zhou, Xinran Zhou, Zhengyan Zhang, Qiong Li, Guodong Wang.
       Background: Diabetes mellitus is a global public health issue, often leading to organ damage, complications, and disabilities. Frailty is an age-related syndrome characterized by reduced physiological reserve and increased vulnerability to stressors, significantly affecting the prognosis of older diabetic patients. The prevalence of frailty is notably higher in older adults with diabetes than in those without. Therefore, a bibliometric analysis of research on diabetes-related frailty can provide deeper insights into the current state of this field and inform future research directions.
    Methods: This study retrieved English-language publications on diabetes-related frailty from the Web of Science Core Collection (WOS) database, covering the period from 2005 to 2023. A total of 403 articles were included in the analysis. Statistical analysis and data visualization were conducted using Microsoft Excel, R Studio, VOS viewer, and Cite Space 6.3.R1. The analysis emphasized journals, authors, keywords, country collaborations, institutional collaborations, and references to elucidate trends and knowledge structures within the field of diabetes-related frailty research.
    Results: The number of publications on diabetes-related frailty has been steadily increasing each year, with research predominantly focused in developed countries, particularly the United States and Europe. The University of London has emerged as the institution with the highest volume of publications, while Alan J. Sinclair has been recognized as a significant contributor to this field. Key research hotspots include the complications associated with diabetes-related frailty, epidemiology, and quality of life. Additionally, a timeline analysis of references suggests that diabetic nephropathy is currently at the forefront of research in this area.
    Conclusion: This comprehensive bibliometric analysis of diabetes-related frailty research underscores the necessity for improved international collaboration to further investigate the mechanisms underlying diabetes-related frailty and to devise more effective prevention and treatment strategies. Future research should emphasize the relationship between diabetic nephropathy and frailty, as well as the development of personalized intervention programs tailored for frail diabetic patients.
    Keywords:  Cite Space; VOS viewer; bibliometrics; diabetes; frailty
    DOI:  https://doi.org/10.3389/fmed.2025.1529218
  30. J Craniofac Surg. 2025 Mar 26.
    Mapping the Evolving Trend of Research on Skeletal Class II Malocclusion Treated With Orthognathic Surgery: A Bibliometric and Visualized Analysis.
    Yuhan Wang, Pin Lv, Pengfei Diao, Bi Zhao, Yuan Yao, Jie Cheng.
       OBJECTIVES: This study aims to provide visual knowledge maps highlighting the evolving trends and key focus areas in treating skeletal Class II malocclusion with orthognathic surgery, using a comprehensive bibliometric analysis.
    MATERIAL AND METHODS: Papers on skeletal Class II malocclusion treated with orthognathic surgery, published between January 2000 and December 2023, were retrospectively sourced from the Web of Science Core Collection. The analysis assessed and visualized the distribution of papers, journals, countries/regions, institutions, authors, and keywords using CiteSpace software.
    RESULTS: A total of 290 relevant publications were included in the analysis. The annual number of publications showed a steady increase, with a significant rise over the past few years. Concerning output and citations, the leading journal is the American Journal of Orthodontics and Dentofacial Orthopedics. The USA and Centre Hospitalier Universitaire de Lille were the most prolific countries and institutions. Furthermore, orthognathic surgery, malocclusion, and stability were identified as the keywords with the most frequencies. Research interests gradually shifted from orthognathic surgery, malocclusion, and stability to quality of life, orthodontic-orthognathic therapy, and temporomandibular joint.
    CONCLUSIONS: Our results provide knowledge maps of that illustrate advancing research trends and key topics about skeletal Class II malocclusion treated with orthognathic surgery, which are anticipated to provide valuable guidance for future research.
    DOI:  https://doi.org/10.1097/SCS.0000000000011314
  31. Rev Environ Health. 2025 Mar 31.
    Global research trends and emerging hotspots in acute high altitude illness: a bibliometric analysis and review (1937-2024).
    Yongjiang Zhou, Hanyu Ding, Hongyin Liang, Yiwen Zhao, Jiajie Feng, Kexin Jiang, Ruiwu Dai.
       INTRODUCTION: Acute High Altitude Illness (AHAI) includes conditions such as Acute Mountain Sickness (AMS), High Altitude Cerebral Edema (HACE), and High Altitude Pulmonary Edema (HAPE), which result from rapid ascent to altitudes exceeding 2,500 m. Although interest in AHAI research has been growing, a systematic and comprehensive analysis of global research trends remains lacking.
    CONTENT: A total of 3,214 articles and reviews published from 1937 to 2024 were retrieved from the Web of Science Core Collection. Bibliometric tools, including CiteSpace and VOSviewer, were applied to thoroughly assess publication trends, collaborative networks among authors, institutional contributions, and keyword co-occurrence patterns. The dataset represents the contributions of over 11,758 authors across 86 countries and 3,378 institutions, reflecting the significant growth of this research domain.
    SUMMARY AND OUTLOOK: Our findings highlight the increasing scholarly attention to AHAI research, with the United States leading in publication numbers. Emerging research themes include cellular activation, oxidative stress, risk factors, and hypobaric hypoxia. This is the first systematic bibliometric review of AHAI literature, offering a detailed roadmap of research hotspots, potential collaborations, and key future directions. These findings provide a valuable reference for researchers aiming to explore gaps and build on the existing knowledge in high-altitude medicine.
    Keywords:  acute high altitude illness; acute mountain sickness; bibliometric analysis; high-altitude cerebral edema; high-altitude pulmonary edema; research hotspots
    DOI:  https://doi.org/10.1515/reveh-2024-0144
  32. Neurosurg Rev. 2025 Mar 22. 48(1): 315
    A bibliometric and visualized analysis of interventional treatment for intracranial atherosclerotic stenosis (from 2004 to 2023).
    Kai Du, Jieqin Gong, Jizhen Li, Hanchun Chen, Qi Fang.
      Intracranial atherosclerotic stenosis is a notable factor leading to ischemic strokes, with a sustained elevated risk of recurrence despite intensive medical management. Recent years have witnessed a surge in research focusing on interventional strategies for addressing this condition. This study seeks to assess the current state and future development paths of interventional therapies for intracranial atherosclerotic stenosis, offering critical insights and recommendations for future research endeavors in this field. A comprehensive bibliometric evaluation was conducted using the bibliometric analysis tools VOSviewer_1.6.20 and CiteSpace 6.3.1, sourcing data from the Web of Science Core Collection database. This analysis encompassed literature related to interventional treatments for intracranial atherosclerotic stenosis from 2004 to 2023, supplemented by graphical illustrations. Following a thorough screening process, we identified 3,384 articles suitable for inclusion in this analysis. An observable increase in publication volume has been noted over the last two decades, with the United States leading in the number of publications. Interestingly, China has shown a significant rise in publication activity in recent years, with Capital Medical University being a prominent contributor. Noteworthy authors in this domain include Derdeyn, C.P. and Levy, E.I., and the Journal of Neurointerventional Surgery has emerged as the primary venue for these articles. The domain of interventional treatments for intracranial atherosclerotic stenosis presents considerable potential for future developments, highlighting the need for a concerted approach towards personalized and precise therapeutic strategies grounded in rigorous multicenter research.
    Keywords:  Bibliometric analysis; CiteSpace; Interventional treatment; Intracranial atherosclerotic stenosis; VOSviewer
    DOI:  https://doi.org/10.1007/s10143-025-03473-6
  33. Curr Neuropharmacol. 2025 Mar 25.
    The Current Research Landscape on the Machine Learning Application in Autism Spectrum Disorder: A Bibliometric Analysis From 1999 to 2023.
    Xinyu Li, Wei Huang, Rongrong Tan, Caijuan Xu, Xi Chen, Qian Zhang, Sixin Li, Ying Liu, Huiwen Qiu, Changlong Bi, Hui Cao.
       BACKGROUND: Language deficits, restricted and repetitive interests, and social difficulties are among the characteristics of autism spectrum disorder (ASD). Machine learning and neuroimaging have also been combined to examine ASD. Utilizing bibliometric analysis, this study examines the current state and hot topics in machine learning for ASD.
    OBJECTIVE: A research bibliometric analysis of the machine learning application in ASD trends, including research trends and the most popular topics, as well as proposed future directions for research.
    METHODS: From 1999 to 2023, the Web of Science Core Collection (WoSCC) was searched for publications relating to machine learning and ASD. Authors, articles, journals, institutions, and countries were characterized using Microsoft Excel 2021 and VOSviewer. Analysis of knowledge networks, collaborative maps, hotspots, and trends was conducted using VOSviewer and CiteSpace.
    RESULTS: A total of 1357 papers were identified between 1999 and 2023. There was a slow growth in publications until 2016; then, between 2017 and 2023, a sharp increase was recorded. Among the most important contributors to this field were the United States, China, India, and England. Among the top major research institutions with numerous publications were Stanford University, Harvard Medical School, the University of California, the University of Pennsylvania, and the Chinese Academy of Sciences. Wall, Dennis P. was the most productive and highest-cited author. Scientific Reports, Frontiers In Neuroscience Autism Research, and Frontiers In Psychiatry were the three productive journals. "autism spectrum disorder", "machine learning", "children", "classification" and "deep learning" are the central topics in this period.
    CONCLUSION: Cooperation and communication between countries/regions need to be enhanced in future research. A shift is taking place in the research hotspot from "Alzheimer's Disease", "Mild Cognitive Impairment" and "cortex" to "artificial intelligence", "deep learning", "electroencephalography" and "pediatrics". Crowdsourcing machine learning applications and electroencephalography for ASD diagnosis should be the future development direction. Future research about these hot topics would promote understanding in this field.
    Keywords:  Autism spectrum disorder; Citespace; Hot-spots; VOSviewer.; bibliometric analysis; machine learning
    DOI:  https://doi.org/10.2174/011570159X332833241222191422
  34. Acta Haematol. 2025 Mar 21. 1-31
    A Bibliometric Analysis of Immunotherapy in Diffuse large B-cell lymphoma from 2004 to 2024.
    Yanling Wu, Xiaomin Chen, Yang Liu, Yu Zhao, Lixiu Luo, Qiuwen Mi, Xiaoying Wen, Chunlan Huang.
       INTRODUCTION: Immunotherapy in DLBCL (diffuse large B-cell lymphoma disease) has become an active research area with great value and potential. However, bibliometric research in this area is still sparse. Through bibliometric analysis, we aimed to visualize the research hot spots and trends of immunotherapy in DLBCL disease to help understand the future development of basic and clinical research.
    METHODS: The Web of Science Core Collection database was searched for articles and reviews related to the immunotherapy of DLBCL from 2004 to 2024. VOSviewers, CiteSpace, and the R package "bibliometrix" were used to conduct the bibliometric analysis.
    RESULTS: A total of 662 articles were included. The number of immunotherapy treatments in DLBCL increased year by year. The publications came from 55 countries, led by the United States and the People's Republic of China, and 1,349 institutions, with the leading research institutions being The University of Texas MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center. Leukemia &amp; lymphoma is the journal with the most research, and Blood is the journal with the most co-citations. We identified 4833 authors, among which Young and Ken H had the most significant articles, while Neelapu SS had the largest number of co-citations. After analysis, the most common keyword is CAR T. CAR T cells (chimeric antigen receptor T cells immunotherapy), a current and developing area of research.
    CONCLUSIONS: This is the first bibliometric study to comprehensively summarize research trends and advances in immunotherapy in DLBCL disease. This information will provide a reference for researchers and healthcare providers in immunotherapy research by clarifying recent research frontiers and hotspots such as CAR T cells, bispecific antibodies, and so on.
    DOI:  https://doi.org/10.1159/000545152
  35. J Multidiscip Healthc. 2025 ;18 1655-1678
    A Bibliometric Analysis of Research Trends in Psychological Interventions for Stroke Survivors: Focusing on Resilience and Psychological Well-Being (2000-2024).
    Yaoyao Li, Kim Lam Soh, Xiujuan Jing, Lili Wei, Hasni Idayu Saidi, Kim Geok Soh.
       Purpose: This study aims to conduct a bibliometric analysis of research literature on psychological interventions for stroke survivors published from 2000 to 2024, focusing on psychological resilience and psychological well-being, utilizing VOSviewer and CiteSpace.
    Patients and Methods: Literature data was sourced from the Web of Science Core Collection database (WoSCC). A total of 373 relevant articles published between January 1, 2000, and September 30, 2024, were included. CiteSpace and VOSviewer analyzed the literature from perspectives including authorship, country of origin, institutions, journals, references, and keywords.
    Results: Annual publication output has steadily increased, reaching a peak in 2023 (55 articles). Vranceanu Ana-Maria emerged as the most productive author with eight publications. The United States led in research output (98 articles) and centrality (0.32), with Harvard University being the leading institution (24 articles). "Disability and Rehabilitation" was the most productive journal (12 articles), while "Stroke" was the most co-cited journal (241 times). Recent research trends emphasized meta-analysis (strength=3.6), assessment tool validation (strength=3.49), and acceptance-based interventions (strength=2.89), mainly focusing on psychological resilience cultivation and well-being promotion.
    Conclusion: This bibliometric analysis reveals the increasing scholarly interest in psychological interventions for stroke survivors, particularly in resilience and psychological well-being research. The field has evolved from focusing on disease-related factors to systematic intervention research, with a growing emphasis on methodological standardization and individualized interventions. These findings provide significant theoretical and practical implications for improving psychological health services for stroke survivors. Future research should strengthen high-quality empirical studies, refine assessment tools, and innovate intervention strategies to better address the complex psychological needs of stroke survivors and enhance their resilience and psychological well-being, ultimately improving rehabilitation outcomes and quality of life for stroke survivors.
    Keywords:  CiteSpace; bibliometric analysis; psychological intervention; psychological resilience; psychological well-being; stroke survivors
    DOI:  https://doi.org/10.2147/JMDH.S505135
  36. Front Surg. 2025 ;12 1461319
    Global trends of laser bone ablation: bibliometric analysis of publications from 1979 to 2023.
    Kai-Jun Zhang, Qi Liu, Teng Zhang, Anjie Shen, Wei Han, Jinqi Li, Bin Zhao, Junqiang Wang.
       Objectives: The objective of the bibliometric analysis was to quantify and identify the current status and trends of laser bone ablation research from 1979 to 2023.
    Materials and methods: The Web of Science (WOS) core collection database was used to search for articles on laser bone ablation published from 1979 to 2023. The collected data were then imported into Microsoft Excel, VOSviewer, and CiteSpace for detailed analysis and visualization.
    Results: A total of 383 articles were included for analysis. The United States made the most significant contributions to the field in terms of both quantity and quality. Moreover, Cattin, Philippe C emerged as the author with the highest number of publications, while the University of Basel stood out as the institution with the greatest publication output. Lasers in Surgery and Medicine emerged as not only the journal with the most publications but also held considerable influence within its domain. Prominent keywords that surfaced frequently included "ablation," "er:yag laser," and "bone."
    Conclusion: The annual number of publications in the field of laser bone ablation is showing an overall upward trend. Research on laser bone ablation primarily focuses on investigating the parameters of this technique, as well as its application in treating bone tumors, performing laser stapes surgery, and various applications of laser bone ablation. The laser osteotomy, laser ablation of bone tumors, animal experiments, and the interaction with biological tissues during laser bone ablation are expected to be the focal areas and future directions in this field.
    Keywords:  CiteSpace; VOSviewer; bibliometrics analysis; bone ablation; laser; visual analysis
    DOI:  https://doi.org/10.3389/fsurg.2025.1461319
  37. West J Emerg Med. 2025 Mar;26(2): 353-363
    Analysis of the Highest Altmetrics-scored Articles in Emergency Medicine Journals.
    Başak Bayram, Murat Cetin, Önder Limon, Brit Long, Michael Gottlieb.
       Introduction: Alternative metrics (altmetrics) have emerged as invaluable tools for assessing the influence of scholarly articles. In this study we aimed to evaluate correlations between Altmetric Attention Scores (AAS), and sources and actual citations in articles displaying the highest AAS within emergency medicine (EM) journals.
    Methods: We conducted an analysis of EM journals listed in the Science Citation Index Expanded (SCIE) using the Altmetric Explorer tool. We analyzed the journals that received the highest number of mentions, the sources of AAS, the regions most frequently mentioned, and the geographical distribution of mentions. In the subsequent stage of our analysis, we conducted an examination of the 200 top-ranked articles that had received high AAS and were published in SCIE EM journals from January 1, 2013-January 1, 2023. We sought to determine the correlations between the AAS and the citation counts of articles on Google Scholar and the Web of Science (WOS).
    Results: Of 40,840 research outputs evaluated, there were 510,047 shares across multiple platforms. The AAS were present for 36,719 articles (89.9%), while 10.1% had no score. In the review of the top 200 articles with the highest AAS, the median score was 382.5 (interquartile range 301.3-510.8). Of the research output evaluated, 38% were observational studies, 13% case reports, and 13% reviews/meta-analyses. The most common research topics were emergency department (ED) management and COVID-19. There was no correlation between AAS and WOS citation numbers (rs = -0.041, P = 0.563, 95% confidence interval [CI] -0.175-0.087). There was a weak correlation identified between WOS citations and mentions on X, and a moderate correlation observed for WOS citations and blog mentions (rs = 0.330, P < .001, 95% CI 0.174 to 0.458; rs 2 = 0.109, and rs = 0.452, P < .001, 95% CI 0.320-0.566; and rs 2 = 0.204, respectively). However, we found a strong positive correlation between WOS citations and the number of Mendeley readers (rs = 0.873, P < .001, 95% CI 0.82-0.911, rs 2 = 0.762).
    Conclusion: While most articles in EM journals received an AAS, we found no correlation with traditional citation metrics. However, Mendeley readership numbers showed a strong positive correlation with citation counts, suggesting that academic platform engagement may better predict scholarly impact.
    DOI:  https://doi.org/10.5811/westjem.21201
  38. Pharmaceuticals (Basel). 2025 Feb 24. pii: 312. [Epub ahead of print]18(3):
    Mapping the Evolution of IBD Treatment: A Bibliometric Study on Biologics and Small Molecules.
    Huibo Li, Jia Wang, Yang Hu, Wei Hu, Jun Li, Yang Liu, Rongsheng Zhao, Yi Zhun Zhu.
      Objectives: This bibliometric analysis investigates recent research trends in biologics and small molecules for treating inflammatory bowel disease (IBD) based on literature from the past decade. Methods: This cross-sectional study involved analyzing data retrieved from the Web of Science Core Collection (WoSCC) database to examine the evolution and thematic trends of biological agents and small-molecular drugs for IBD conducted between 1 January 2014, and 20 September 2024. VOSviewer software was utilized to assess co-authorship, co-occurrence, co-citation, and network visualization, followed by a further discussion on significant sub-themes. Results: From 2014 to 20 September 2024, the annual number of global publications increased by 23%, reflecting an acceleration in research activity. The journal "Inflammatory Bowel Diseases" published the highest number of manuscripts (579 publications) and garnered the most citations (13,632 citations), followed by the "Journal of Crohn's & Colitis" (480 publications) and "Alimentary Pharmacology & Therapeutics" (250 publications). The United States led in productivity with 1943 publications and 66,320 citations, with UC San Diego (291) and authors Sandborn and Vermeire (180) topping the list. The co-occurrence cluster analysis of the top 100 keywords resulted in the formation of six distinct clusters: Disease Mechanisms, Drug Development, Surgical Interventions, Therapeutic Drug Monitoring (TDM), Immunological Targets, and Emerging Therapies. Burst terms (TNF-α inhibitors, JAK inhibitors, and trough-level optimization) highlight trends toward personalized biologics and small-molecule regimens. Conclusions: The bibliometric analysis indicates that IBD therapeutic research and clinical applications focus on biologics and small molecules, with research trends leaning toward precise therapy conversion or the combination in non-responders. Future work will assess monotherapy, the combination, and conversion therapies and investigate new drugs targeting inflammatory pathways.
    Keywords:  bibliometric study; biological product; inflammatory bowel disease; small molecules
    DOI:  https://doi.org/10.3390/ph18030312
  39. Medicine (Baltimore). 2025 Mar 21. 104(12): e41927
    Identifying research activity on brain ultrasonography in craniocerebral diseases by bibliometric and visualized analysis of a 20-year journey of global publications.
    Zaiyang Yu, Jinting Xiao, Fengqian Ma, Shengjie Li.
      Brain ultrasonography has emerged as a key tool in neurocritical care. This study aimed to investigate the global research trends and future research directions in the application of brain ultrasonography for craniocerebral diseases using quantification and visualization approaches. Publications on brain ultrasonography published between 2004 and 2024 retrieved from the Web of Science Core Collection database were screened against predetermined inclusion and exclusion criteria and analyzed. The data were processed using VOSviewer and CiteSpace to identify core countries/regions, institutions, authors, journals, collaborations, and research trends. Over the past 2 decades, 1251 articles focusing on brain ultrasonography as the primary subject were published across 455 journals by 5655 authors from 1619 institutions in 84 countries/regions. Publications exhibited a fluctuating and gradually progressive trend, with the number of publications per year peaking between 2019 and 2021. The USA, the United Kingdom, and Germany emerged as leading countries in this field, demonstrating robust cooperation with other countries/regions. Additionally, the University of Leicester and Panerai RB was the most prolific institution and author, respectively. The clinical applications of brain ultrasonography have progressively broadened from neurocritical care to encompass the general intensive care unit and emergency department. Finally, recent scholarly attention has primarily been directed toward the "deep learning framework" and "hypoxic-ischemic brain injury." Globally, publications focusing on brain ultrasonography displayed a fluctuating and gradually progressive trend over the past 2 decades. Moreover, primary clinical applications and techniques have been constantly expanding. Overall, the findings of our study expanded our understanding of the current status of brain ultrasonography, potentially guiding future development directions in this field.
    DOI:  https://doi.org/10.1097/MD.0000000000041927
  40. Front Psychol. 2025 ;16 1463671
    Exploring the relationship between social media dependence and internet addiction among college students from a bibliometric perspective.
    Ruotong Dong, Dongfeng Yuan, Xue Wei, Jingyi Cai, Zhongzhu Ai, Shiquan Zhou.
       Background: Social media use among college students often leads to psychological dependence, resulting in a rising number of internet addictions. The link between social media dependence and addiction is garnering increasing attention.
    Objective: The aim of this study was to analyze and discuss the research trends and hotspots on social media dependence and internet disorder among college students by bibliometric methods.
    Methods: Relevant studies on social media dependence and online addiction among college students were retrieved from the Web of Science (WoS) database spanning the years 2013 to 2024. We delineated the distribution of publications to identify the core productivity within the field. VOSviewer software was employed to conduct network visualization analyses of countries, authors, journals, and keywords, aiding in a comprehensive understanding of the research trends and hotspots in this domain.
    Results: From the WoS database, we retrieved 302 publications, and 167 publications were included after screening. The findings revealed: (1) a steady increase in publications and citations, particularly accelerating after 2019. (2) The most productive journal is Computers in human behavior, the most productive research area is Psychology, and the most productive author, institution, and country are Professor Griffiths MD, Nottingham Trent University and China, respectively. (3) Collaborative network analysis indicated that there were multiple research groups in this field, yet the connections among countries and authors remain relatively limited. (4) Co-citation analysis of journals revealed that this field was interdisciplinary, primarily integrating psychology, psychiatry, and behavioral science. (5) Keyword analysis identified two major research hotspots: the relationship between college students' social media dependence and internet addiction, and the mediating factors influencing college students' social media dependence and internet addiction. The mechanism of internet addiction is an emerging research frontier.
    Conclusion: This analysis outlines the progress and directions of research on college students' social media dependence and internet addiction. It offers a comprehensive examination of the latest frontiers and trends, providing theoretical support for regulating the use of electronic products and implementing mental health interventions in college students.
    Keywords:  VOSviewer; bibliometric; college students; internet addiction; social media; systematic review
    DOI:  https://doi.org/10.3389/fpsyg.2025.1463671
  41. Open Life Sci. 2025 ;20(1): 20251071
    Emerging patterns in nanoparticle-based therapeutic approaches for rheumatoid arthritis: A comprehensive bibliometric and visual analysis spanning two decades.
    Shenwei Xie, Pan Liao, Shuang Mi, Liang Song, Xiaoyuan Chen.
      The aim of this study is to analyze scientific literature to investigate the current research status, focus areas, and developmental trends in nanoparticle systems for rheumatoid arthritis (RA) therapy. To do that, Research articles published from 2003 to 2023 were retrieved from the Web of Science database, and analysis included quantitative output, distribution by country/region, collaborative publishing data, influential authors, high-yield institutions, keywords, hotspots, and development trends. Visual knowledge maps were generated using VOSviewer and Citespace. Findings reveal a steady increase in publications related to nanoparticle systems for RA therapy, indicating growing global interest. China leads with 487 papers (37.433%), followed by the United States (233, 17.909%), India (179, 13.759%), South Korea (89, 6.841%), and Egypt (50, 3.843%). Active collaboration is observed, particularly between the United States and countries such as China, Germany, Saudi Arabia, India, England, and Pakistan. The Chinese Academy of Sciences ranks first in total articles published (55), with Liu Y from China being the most prolific author. The Journal of Controlled Release emerges as a primary outlet in this field. Primary keyword clusters include "Drug delivery systems," "Gold nanoparticles," "Transdermal delivery," "Angiogenesis," "Collagen-induced arthritis," "Rheumatoid arthritis," "Oxidant stress," "Dendritic cells," and "pH sensitive." Research hotspots with great development potential include "Immunopathological Mechanisms," "Novel drugs," and "Smart delivery system." In conclusion, research on nanoparticle systems for RA therapy has significantly expanded over the past two decades, with a focus on elucidating pathogenetic mechanisms and advancing novel drug delivery strategies anticipated to be prominent in the foreseeable future.
    Keywords:  bibliometrics; global trends; nanoparticles; rheumatoid arthritis; visualization study
    DOI:  https://doi.org/10.1515/biol-2025-1071
  42. J Transl Med. 2025 Mar 24. 23(1): 365
    Global research trends in mind body therapies: a bibliometric analysis.
    Yunxiao Zhang, Wenwen Li, Sai Xu, Shudi Li, Zhen Hai Sun, Menghe Zhang, Yaoyao Zuo, Shouqiang Chen.
       OBJECTIVES: Mind-body therapies are a group of treatments based on the theory of mind-body medicine, which are effective for a wide range of illnesses. However, there are no bibliometric papers that have examined the topic of mind-body therapies. Therefore, it is necessary to review and sort out the current status, hotspots and frontiers of mind-body therapies.
    METHODS: Studies related to mind-body therapies during the period of Web of Science 1999-01/2024-07 were searched, and R language was applied to analyze the data and CiteSpace, Vosviewer software, was used to generate visualization maps.
    RESULTS: A total of 29,710 relevant articles were included in the study. The country with the highest number of publications was the United States, followed by China and the United Kingdom, and the prolific author was Wang Yuan. Common keywords were acupuncture, quality of life, depression, and pain. The current study focuses on the promotion and application of mind-body therapies in various diseases, the main applicable diseases and the application in special groups.
    CONCLUSION: This study presents the current status and trend of research on mind-body therapies, and inflammatory interventions and higher-level research assessment methods are potential hotspots, which can help researchers to clarify hotspots and explore new directions.
    Keywords:  Bibliometric analysis; CiteSpace; Mind-body therapies; VOSviewer; Visualization
    DOI:  https://doi.org/10.1186/s12967-025-06389-3
  43. Regen Ther. 2025 Jun;29 19-34
    Comprehensive bibliometric analysis and perspectives on therapies targeting colon cancer stem cells over a 40-year period.
    Şeyda Berk.
      The presence of cancer stem cells (CSCs) is one of the primary causes of recurring therapy resistance because they have two main capacities: self-renewal and avoiding apoptotic pathways. Despite their relevance, no full bibliometric analysis has yet been done in this topic. The goal of this work is to use bibliometric analysis to map the fundamental and emergent areas in therapeutics targeting colon cancer stem cells. To perform bibliometric analysis on colon cancer stem cells (CCSCs) literature, spanning roughly the last 40 years, in order to establish a firm base for future projections by emphasizing the findings of the most notable research. All information pertinent to CCSCs was accessed from Web of Science Core Collection database. In order to identify and analyze the research hotspots and trends related to this topic, Biblioshiny (RStudio) and VOSviewer were utilized to ascertain the countries/regions, institutions, journals, authors, references, and keywords involved. The targeted time span covered 1735 research-, and review articles. The most frequent keywords were "colorectal cancer," "cancer stem cells," and "colon cancer," while the most trending keywords in the last few years were "protein stability," "spheroid formation," "ubiquitination," "exosomes," "patient-derived organoids," and "gut microbiota." Over the past 40 years, there has been a significant advancement in researchers' understanding of colon cancer stem cells. In addition, the cluster map of co-cited literature showed that colon cancer stem cell research has emerged as a research hotspot. It was also anticipated that the main focus of the future efforts appears to involve clinical applications of cell-targeted colon cancer therapy. These results provide researchers with a comprehensive understanding of this field and provide insightful ideas for further research.
    Keywords:  Bibliometry; Biblioshiny; Colon cancer stem cells; R-Bibliometrix; VOSviewer; Web of Science
    DOI:  https://doi.org/10.1016/j.reth.2025.02.015
  44. J Surg Res. 2025 Mar 21. pii: S0022-4804(25)00094-0. [Epub ahead of print]308 216-223
    Predictors of Academic Productivity in Cardiac Surgeons: Quality Over Quantity.
    Anirudha S Chandrabhatla, Adishesh K Narahari, Emily D Fronk, Aditya Singh, Kennedy Gray, Kevin T Qiu, Theodore Vasiliadis, Joseph D Nguyen, Nicholas R Teman, John A Kern, Ourania A Preventza, J Hunter Mehaffey, Mark E Roeser.
       INTRODUCTION: Building a successful academic career is challenging. It is unclear which metrics of academic productivity best predict future success for cardiac surgeons.
    METHODS: We collected academic cardiac surgeon profiles from the top 140 National Institutes of Health (NIH)-funded institutions. Publication information was obtained from Web of Science and the NIH iCite tool. Grant information was collected from NIH Research Portfolio Online Reporting Tools Expenditures and Results. Data were categorized into distinct time periods as follows for each surgeon: last 5 y of training (senior trainee), first 5 y as an attending (junior faculty), and after 5 y as an attending (established faculty). The primary outcomes of: (1) publications as established faculty and (2) receiving a K08 or R01 were analyzed using linear and logistic regression.
    RESULTS: We analyzed 972 academic cardiac surgeons. Total publications as established faculty were predicted by citations per year of papers published as a senior trainee (P = 0.015) but not the number of publications as a senior trainee (P = 0.14). The proportion of basic or translational research (P = 0.27) and first author publications as a senior trainee (P = 0.18) did not predict total publications as established faculty. Being awarded a K08 or R01 was predicted by the number of publications as junior faculty (P = 0.001; odds ratio (OR) 1.02) and whether the surgeon was awarded an F32 (P = 0.0004; OR 3.97) but not the number of publications as a senior trainee (P = 0.49; OR 1.01). Publishing a higher proportion of senior author papers as junior faculty also predicted being awarded a K08 or R01 (P < 0.001; OR 17.15). The surgeons in the top quartile by publication volume varied substantially across career time points.
    CONCLUSIONS: Research quality, not quantity, as a trainee predicts future academic productivity as an attending. Cardiac surgery trainees should prioritize learning how to conduct high-quality research and apply those skills as early attendings to position themselves for future academic success.
    Keywords:  Academic surgery; Cardiac surgery; Career development; Resident education
    DOI:  https://doi.org/10.1016/j.jss.2025.02.033
  45. Diabetes Res Clin Pract. 2025 Mar 23. pii: S0168-8227(25)00132-9. [Epub ahead of print]223 112118
    When COVID-19 meets diabetes: A bibliometric analysis.
    Yingli He, Qingcong Zheng, Zhang Zhifang, Nie Xiaofeng, Wu Shenggen, Mengzhou Xue, Chunfu Zheng, Zhijun Liu.
      Coronavirus disease 2019 (COVID-19) survivors are concerned about the likelihood of developing further diseases. This study examines the global trends in scientific research on diabetes associated with COVID-19 from several perspectives. Bibliometric analyses are used to undertake a scientific review of the literature. The Web of Science Core Collection (WoSCC) database was used to acquire bibliographic information on diabetes related to COVID-19 from Jan 2020 to Dec. 2023. The visual map was built via advanced CiteSpace 6.2.R6. 7,348 papers were found. Khunti Kamlesh and Rizzo-Manfredi are the most well-known high-yield authors in this area, and the top ten authors collaborate extensively. Most of these papers came from universities. Harvard Medical School has the most publications, followed by Wuhan University and Huazhong University of Science and Technology. China and the United States are the countries with the most publications. Angiotensin-converting enzymes, chronic disease, intensive care unit, viral infection, and gestational diabetes mellitus were scored 0-11, 2, 3, and 4, respectively. Zhou et al.'s work on this topic, which appeared in the prominent medical journal The Lancet, was cited 1,366 times, highlighting its importance. "clinical characteristics," "diabetes mellitus," "metabolic syndrome," and "angiotensin-converting enzyme" were used as keywords for reference co-citation and clustering data identify. Over the last four years, related investigations have focused primarily on observing clinical aspects. This report is important for developing treatment strategies, directing future research, and guiding clinical practice.
    Keywords:  ACE2, bibliometrics; Bidirectional relationship; COVID-19-related diabetes; CiteSpace; Combined analysis; Coronavirus disease 2019 (COVID-19)
    DOI:  https://doi.org/10.1016/j.diabres.2025.112118
  46. Cureus. 2025 Feb;17(2): e79509
    Repetitive Transcranial Magnetic Stimulation in Stroke Rehabilitation: A Bibliometric Review.
    Ayesha Juhi, Rintu K Gayen, Shreya Sharma, Pritam K Choudhary, Himel Mondal.
      Stroke is a major cause of disability globally, with rehabilitation playing a crucial role in restoring lost functions. Despite advancements, many stroke survivors face persistent deficits, prompting the need for innovative approaches such as repetitive transcranial magnetic stimulation (rTMS). This non-invasive technique promotes neural plasticity and recovery by modulating cortical excitability, garnering significant research interest. This bibliometric analysis of rTMS research in stroke rehabilitation was conducted to find publication trends and influential studies. Data were collected from the Web of Science (WOS) with search strings as follows: TI = ((repetitive transcranial magnetic stimulation) OR rTMS) AND TI = ((stroke) OR stroke rehabilitation). The studies till the 31st of December 2024 were included. No language or other filters were applied. A total of 556 studies were identified. While analyzing the data, there may be a higher or lower count of the total number of studies due to the overlap of categories. For example, a study may have authors from different countries, making the total number of publications according to countries higher than 556. There was a growing interest in rTMS in the context of stroke rehabilitation, with a substantial increase in publications in 2022, 2023, and 2024. Among the studies, the majority of the studies were research articles (62.42%), followed by meeting abstracts (18.41%). The studies (n = 983) were in the fields of clinical neurology (27.47%) and neuroscience (27.37%), followed by rehabilitation (8.55%). When studies (n = 645) were categorized according to countries, The People's Republic of China had the majority of the studies (29.92%), followed by South Korea (11.01%), the USA (10.85%), and Japan (9.61%). Elsevier (15.83%) leads in publishing the articles, followed by Frontiers Media (13.49%). The top citation was for the article titled "Repetitive Transcranial Magnetic Stimulation of Contralesional Primary Motor Cortex Improves Hand Function After Stroke" with 521 citations and was published in the journal Stroke. These findings provide valuable insights into research trends, influential studies, and global collaboration, emphasizing the potential of rTMS in advancing stroke recovery. More studies are needed from diverse geographical regions with possible international collaboration.
    Keywords:  bibliometrics; brain; cognition; cortical excitability; magnetic phenomena; neuronal plasticity; review literature as topic; sensation; stroke rehabilitation; transcranial magnetic stimulation
    DOI:  https://doi.org/10.7759/cureus.79509
  47. Pediatr Pulmonol. 2025 Apr;60(4): e71064
    Controversies in Pediatric Asthma: A Bibliometric Evaluation.
    Kadeliya Abulimiti, Kutiluke Shoukeer, Xinhui Luo.
       OBJECTIVE: Pediatric asthma is a common chronic inflammatory airway disease in children. This paper analyzes research literature on pediatric asthma and its treatment over the past decade using bibliometric methods, discussing research hotspots and trends to guide future studies.
    METHOD: The Web of Science database was selected as the data source, with the retrieval period from January 1, 2014, to January 1, 2025. This study collected and analyzed literature on pediatric asthma and its treatment from the past decade, covering aspects such as publication volume, countries, institutions, journals, authors, and keywords.
    RESULTS: The search yielded 640 documents involving 68 countries and 1208 institutions, authored by 3506 researchers and published across 259 journals. The global annual average publication volume of 56.8 articles indicates active research in this field. China ranks second globally in publication volume, yet there is a gap in research quality and international influence compared to Western countries. Pediatric asthma treatment remains a core challenge in the pediatric and respiratory fields, making it a central research focus for the future.
    CONCLUSION: Asthma has become a major health issue among children. Over the past decade, substantial progress has been made globally in the research of pediatric asthma and its treatment. Despite surpassing many developed countries in publication volume, China needs to enhance the quality and impact of its research. There is a hope that China will increase investment in scientific research and publish more high-quality articles in both domestic and international prestigious journals, advancing the country's development in this field.
    Keywords:  Bibliometrics; asthma; pediatric asthma; respiratory diseases; visual analysis
    DOI:  https://doi.org/10.1002/ppul.71064
  48. Dialogues Health. 2025 Jun;6 100210
    Migration and Women's Health Research (2000-2023): A bibliometric analysis of trends and gaps.
    Aasif Hussain Sheikh, Snober Hamid, Bilal Ahmad Lone, Farheena Muzaffar, Manzoor Hussain.
      This bibliometric study examines the scholarly landscape of migration and women's health, analyzing 1314 Scopus-indexed articles from 462 journals published between 2000 and 2023. Findings indicate a consistent increase in research output, reflecting growing global interest in this interdisciplinary field. Geographically, high-income countries (HICs), including the United States, Canada, the United Kingdom, and Australia, dominate contributions, while low- and middle-income countries (LMICs) remain underrepresented despite hosting significant migrant populations. International collaborations play a crucial role, with key institutions such as the University of California and the London School of Hygiene and Tropical Medicine shaping research efforts. The keyword co-occurrence analysis highlights migration, gender dynamics, mental health, and reproductive health as dominant themes. Persistent gaps in mental and reproductive healthcare access for migrant women emphasize the need for trauma-informed care (TIC), mobile bilingual healthcare services, and inclusive health policies. Disparities in research funding further exacerbate global health inequities, underscoring the necessity of equitable redistribution of resources, including redirecting at least 10 % of HIC research grants to LMIC-led studies. The COVID-19 pandemic magnified pre-existing vulnerabilities, stressing the importance of multilateral collaborations and sustainable policy interventions to enhance migrant healthcare access. This study provides valuable insights into research trends, collaboration networks, and thematic focus areas, offering a foundation for future interdisciplinary research and evidence-based policymaking aimed at promoting health equity for migrant women globally.
    Keywords:  Bibliometric analysis; Health; Migration; Publication trends; Women
    DOI:  https://doi.org/10.1016/j.dialog.2025.100210
  49. Medicine (Baltimore). 2025 Mar 28. 104(13): e41801
    Research trends on spinal muscular atrophy from 1995 to 2023: A bibliometric analysis.
    Hao Yu, Cuijie Wei, Dan Sun, Li Zhang, Yanyan Xia, Wenhua Zhu.
       BACKGROUND: Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by progressive muscle weakness due to motor neuron degeneration. The discovery of the survival motor neuron 1 (SMN1) gene in 1995 revolutionized SMA research, leading to significant therapeutic advancements. This bibliometric analysis aimed to explore global trends in SMA research and therapy, with a particular focus on China.
    METHODS: A comprehensive database search identified 4506 relevant publications (3812 articles, 694 reviews) published between 1995 and 2023. Bibliometric tools were used to analyze publication trends, collaborations, and research topics.
    RESULTS: SMA research has experienced substantial growth, with the United States leading in publications followed by the United Kingdom and Germany. China has shown increasing engagement in this field. Key research areas include genetic and molecular mechanisms, survival motor neuron gene therapy, antisense oligonucleotides, and muscle strength-promoting factors. Chinese researchers have contributed significantly to these areas, with a higher reporting frequency of SMA-related topics compared to other countries.
    CONCLUSION: This bibliometric analysis provides a comprehensive overview of global SMA research, highlighting significant advancements, and identifying future directions. The findings offer valuable insights for researchers, clinicians, and policymakers in China to ensure alignment with global medical advancements and improve the lives of individuals affected by SMA.
    DOI:  https://doi.org/10.1097/MD.0000000000041801
  50. J Educ Health Promot. 2025 ;14 59
    Unveiling the nexus: A bibliometric analysis of nano plastic's health impact.
    Alok Singh, Vanisree Ramanathan, Ujjwal Kumar, Shailesh Tripathi, Sheikh Mohd Saleem, Deep Shikha, Poonam Kushwaha, Sudip Bhattacharya.
      Plastics are integral to daily life due to their flexibility, durability, low viscosity, and poor conductivity. However, UV exposure, weathering, and biodegradation fragment plastics into microplastics and nano plastics, forming a heterogeneous mix categorized as large microplastics (5 mm to 1 mm), small microplastics (1 mm to 1 μm), and nano plastics (<1 μm). Concerns over the health impacts of micro and nano plastic (MNP) pollution have spurred extensive research, revealing increased disease susceptibility. Recent studies, analyzed using tools like Biblioshiny and Vos viewer software, have focused on authorship, journal sources, geographic origins, and emerging trends in MNP research. Data from the SCOPUS database (January 1, 2015 to January 3, 2024) analyzed via Biblioshiny and Microsoft Excel revealed 478 articles, with a steady annual increase in publications and references, highlighting growing interest in nanoplastics' health impacts. China leads in publications and collaborations, with eight of the top ten contributing institutions located there, alongside Spain and Serbia. Chinese authors also dominate the top ten published papers in leading journals, five of which are prominent in Environmental Science. This study presents the first visual metametrological analysis of the connection between nanoplastics and human health using bibliometric techniques. By examining global research on nanoplastics' health implications, we can better understand the current research landscape and set priorities for future studies.
    Keywords:  Health hazards; micro plastic; nano plastic
    DOI:  https://doi.org/10.4103/jehp.jehp_503_24
  51. Curr Neuropharmacol. 2025 ;23(4): 439-457
    Bibliometric Analysis of Antipsychotic-induced Metabolic Disorder from 2006 to 2021 Based on WoSCC Database.
    Zhihao Guo, Zi Zhang, Lu Li, Ming Zhang, Shanqing Huang, Zezhi Li, Dewei Shang.
       BACKGROUND: With the frequent use of antipsychotics, the metabolic disorder (MetD) caused by drugs has received increasing attention. However, the mechanism of drug-induced MetD is still unclear and is being explored. Keeping abreast of the progress and trending knowledge in this area is conducive to further work.
    OBJECTIVE: The aim of this study is to analyze the latest status and trends of research on antipsychoticinduced metabolic disorder (AIMetD) by bibliometric and visual analysis.
    METHODS: 3478 publications of AIMetD from 2006 to 2021 were retrieved from the Web of Science Core Collection database. R-biblioshiny was used for descriptive analysis, CiteSpace for cooperative network, co-citation analysis and burst detection, and VOSviewer for co-occurrence keywords was used.
    RESULTS: Since 2006, the publications have been growing fluctuantly. These studies have extensive cooperation among countries/regions. The most influential country/region, institution and author are the USA, King's College London and Christoph U Correll. Analysis of references shows the largest cluster of "antipsychotic-induced metabolic dysfunction", which is an important basis for MetD. The recent contents of the burst citation are related to "glucose homeostasis" and "cardiovascular metabolism". Several bursting keywords were discerned at the forefront, including "LC-MS/MS", "major depressive disorder", "expression", and "homeostasis".
    CONCLUSION: The AIMetD study is in a state of sustained development. Close cooperation between countries/ regions has promoted progress. For grasping the foundation, development, and latest trends of AIMetD, it is recommended to focus on active institutions and authors. Based on AIMetD, subdivision areas such as "LC-MS/MS", "expression", and "homeostasis" are forefronts that deserve constant attention.
    Keywords:  Antipsychotics; LC-MS/MS; bibliometrics; homeostasis; metabolic disorder; visual analysis
    DOI:  https://doi.org/10.2174/1570159X23666241016090634
  52. Medicine (Baltimore). 2025 Mar 28. 104(13): e41859
    A Bibliometric Analysis of hypertension and anxiety from 2004 to 2022.
    Si-Qi Liu, Xin-Yu Ji, Hai-Yi Liang, Shu-Han Zhao, Fu-Yi Yang, Yang Tang, Shuai Shi.
       BACKGROUND: A growing body of clinical evidence points to an association between hypertension and anxiety, but the mechanisms by which the two occur are unclear. This article aims to explore possible common influences and associations between hypertension and anxiety.
    METHODS: We searched for publications on hypertension and anxiety from January 01, 2004 to December 31, 2022 in Web of Science and performed bibliometrics using CiteSpace, VOSviewer, Scimago Graphica and Gephi.
    RESULTS: A total of 3216 related articles were retrieved from the Web of Science database. After screening, 3051 articles were included. The number of published articles has increased over the past 19 years. The United States has more researches in this area and has strong collaborative relationships with other countries, which gives it some credibility and authority. The words that appear in the burst keywords are gender, age, obesity, depression, panic disorder, pregnancy induced hypertension, coronary heart disease, chronic kidney disease, and pituitary adrenal axi, which are co-related with hypertension and anxiety.
    CONCLUSION: There is a link between hypertension and anxiety, and the 2 influence each other, usually in a positive way. Common influences on hypertension and anxiety include age, gender, obesity, depression, panic attacks, pregnancy, coronary heart disease and chronic kidney disease. Recent research hotspots have focused on population aging and comorbidities. Future research hotspots are likely continue to focus on influencing factors, clinical research and prognosis.
    DOI:  https://doi.org/10.1097/MD.0000000000041859
  53. Healthcare (Basel). 2025 Mar 11. pii: 608. [Epub ahead of print]13(6):
    Progress and Prospects of Research on the Impact of Mental Health of Youth Sailors-A Bibliometric-Based Analysis.
    Milena Lachowicz, Yang Xing, Tomasz Chamera.
      Background: The mental health of youth sailors has garnered increasing attention from both coaches and researchers, as evidenced by the growing appearance of related keywords in scientific literature. Despite this rising interest, no studies have yet specifically focused on the mental health of this population. Methods: This study conducted a bibliometric analysis of 315 articles retrieved from the Web of Science database. These articles were analyzed to identify trends, influential authors, institutions, and regions in the field of youth sailor mental health. Results: The analysis yielded several key findings: (1) Depression, anxiety, and mental health disorders are the primary areas of focus in the literature on youth sailors' mental health; (2) Rosemary Purcell is identified as the most influential author in this domain; (3) the University of Melbourne, Orygen, and Deakin University are the top three contributing institutions; (4) Australia, the USA, Canada, China, and England are the five most prominent regions involved in this research. Conclusions: This study provides a comprehensive overview of current research on the mental health of young sailors. By emphasising the most influential contributors and research trends, it aims to raise awareness amongst coaches and researchers, eventually supporting efforts to improve the mental health of young sailors.
    Keywords:  mental health; sports psychology; well-being; youth athletes; youth sailors
    DOI:  https://doi.org/10.3390/healthcare13060608
  54. Immunol Med. 2025 Mar 28. 1-17
    Bibliometric analysis of systemic lupus erythematosus during pregnancy from 2003 to 2024.
    Xinyan Zou, Xinfu Zou, Qiaoqiao Liu, Bingxin Zhou, Shujie He, Xiulan Liao, Hanqing Zhao.
      Autoimmune diseases such as systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome have a significant impact on pregnancy, potentially exacerbating SLE symptoms and leading to miscarriage, pre-eclampsia and other pregnancy complications. To ensure the safety of SLE patients during pregnancy, experts have conducted in-depth research and provided recommendations. Therefore, it is necessary to provide a thorough summary of the current status, hotspots and emerging trends in this research field. We systematically searched the Web of Science Core Collection database for studies on SLE during pregnancy from 1 January 2003 to 24 March 2024. We then utilized CiteSpace to generate a knowledge visualization map. This analysis included a total of 2239 studies on SLE during pregnancy. The yearly volume of publications exhibits a persistent increasing trend. The United States had the highest number of publications and was the leading country, while the Czech Republic had the highest centrality and influence. The research focused on three main areas: (1) pregnancy outcomes in autoimmune diseases, (2) newborn-related diseases and complications and (3) medication management for patients with SLE during pregnancy. Our study offers both a visual and scientific synopsis of research concerning SLE during pregnancy, furnishing valuable insights and opening up new avenues for researchers.
    Keywords:  CiteSpace; Systemic lupus erythematosus; autoimmune; bibliometrics; pregnancy; pregnant
    DOI:  https://doi.org/10.1080/25785826.2025.2483811
  55. Neurol Int. 2025 Mar 20. pii: 45. [Epub ahead of print]17(3):
    Artificial Intelligence in the Diagnosis of Neurological Diseases Using Biomechanical and Gait Analysis Data: A Scopus-Based Bibliometric Analysis.
    Aikaterini A Tsiara, Spyridon Plakias, Christos Kokkotis, Aikaterini Veneri, Minas A Mina, Anna Tsiakiri, Sofia Kitmeridou, Foteini Christidi, Evangelos Gourgoulis, Triantafylos Doskas, Antonia Kaltsatou, Konstantinos Tsamakis, Dimitrios Kazis, Dimitrios Tsiptsios.
      Neurological diseases are increasingly diverse and prevalent, presenting significant challenges for their timely and accurate diagnosis. The aim of the present study is to conduct a bibliometric analysis and literature review in the field of neurology to explore advancements in the application of artificial intelligence (AI) techniques, including machine learning (ML) and deep learning (DL). Using VOSviewer software (version 1.6.20.0) and documents retrieved from the Scopus database, the analysis included 113 articles published between 1 January 2018 and 31 December 2024. Key journals, authors, and research collaborations were identified, highlighting major contributions to the field. Science mapping investigated areas of research focus, such as biomechanical data and gait analysis including AI methodologies for neurological disease diagnosis. Co-occurrence analysis of author keywords allowed for the identification of four major themes: (a) machine learning and gait analysis; (b) sensors and wearable health technologies; (c) cognitive disorders; and (d) neurological disorders and motion recognition technologies. The bibliometric insights demonstrate a growing but relatively limited collaborative interest in this domain, with only a few highly cited authors, documents, and journals driving the research. Meanwhile, the literature review highlights the current methodologies and advancements in this field. This study offers a foundation for future research and provides researchers, clinicians, and occupational therapists with an in-depth understanding of AI's potentially transformative role in neurology.
    Keywords:  computer vision; deep learning; diagnosing; machine learning; neurology; occupational therapy; rehabilitation; severity
    DOI:  https://doi.org/10.3390/neurolint17030045
  56. J Am Acad Orthop Surg. 2025 Mar 25.
    Geographic Location Markedly Affects Academic Productivity of Pediatric Orthopaedic Surgeons.
    Michael K Viggiano, McKenzie A Mayer, Patrick M Pema, Kevin M Posner, Alexander Rompala, Suleiman Y Sudah, Avrum L Joffe.
       INTRODUCTION: Existing literature lacks clarity on how research output during orthopaedic training correlates with the later productivity of pediatric orthopaedic surgeons. This study aims to examine the academic productivity of pediatric orthopaedic surgeons at different career stages and its relation to geographic training location.
    METHODS: The 2023 to 2024 Pediatric Orthopaedic Society of North America directory was used to identify pediatric orthopaedic fellowship faculty. Training history, current institution, and publication data before residency, during residency, fellowship, and after fellowship were collected. Attending publication rates and H-indices were calculated. Multivariate linear regression assessed relationships between publication numbers at various stages and attending publication rate and H-index. A P value of <0.05 was considered significant. Geographical regions were compared for attending publications, rates, and H-indices.
    RESULTS: A total of 398 pediatric orthopaedic surgeons from 45 fellowship programs were identified. The average number of publications per faculty member was 58.0 ± 72.0, with an H-index of 14.5 ± 13.2. The average attending publication rate was 2.99 ± 3.30. Residency (P < 0.001) and fellowship (P < 0.001) publication numbers were markedly associated with higher attending publication rates. Residency in the northeast was markedly associated with higher total attending publications (P = 0.043), rates (P = 0.021), and H-indices (P = 0.001) compared with other regions.
    DISCUSSION/CONCLUSION: This study shows a strong correlation between higher research output during residency and fellowship, especially in the Northeast, and increased academic productivity as an attending. These findings may affect academic hiring and emphasize the importance of selecting residency and fellowship programs for future research success.
    DOI:  https://doi.org/10.5435/JAAOS-D-24-01061
  57. Pharmaceuticals (Basel). 2025 Mar 16. pii: 420. [Epub ahead of print]18(3):
    Unraveling the Neuropharmacological Properties of Lippia alba: A Scientometric Approach.
    Pedro I C Silva, Lucas V P S Pantoja, Brenda C Conceição, Marta E O Barbosa, Luiza F R Soares, Rui Daniel Prediger, Enéas A Fontes-Júnior, Jofre J S Freitas, Cristiane S F Maia.
      Lippia alba (Verbenaceae) is popularly known as lemon balm or false melissa and is one of the most widely used plants in traditional medicine in the Amazon region. In this study, we conducted a comprehensive bibliometric analysis, with conventional metrics associated with a critical review based on the neuropharmacological activities, to identify potential medical applications and also gaps in knowledge that require further investigation. Fifty-two articles were included according to the eligibility criteria. In the country analysis, Brazil emerged as the main contributor to research with the highest number of publications and citations. Notably, nine of the ten main research institutions are Brazilian, with the Universidade Federal de Santa Maria standing out with 761 citations. The keywords "anesthesia", "Lippia alba", and "essential oil" were the most frequent, highlighting their importance in this field. Essential oils are the most common type of extraction, which linalool, citral, geraniol, carvone, and limonene were the main constituents identified. According to the type of study, preclinical studies presented the highest frequency, primarily through fish experimental models. The main neuropharmacological activities identified were sedative-anesthetic, anxiolytic, anticonvulsant, and analgesic, with mechanisms of action via the GABAergic pathway. This bibliometric review provided new evidence reinforcing the potential of L. alba as a promising alternative for the treatment of neuropsychiatric disorders. It also highlighted existing knowledge gaps, mainly related to the comparison of the actions of the different chemotypes of the species and the investigation of the mechanisms underlying their neuropharmacological properties. Additionally, there is a lack of knowledge in other emerging areas related to the central nervous system, such as mood and cognitive disorders.
    Keywords:  Lippia alba; Verbenaceae; bibliometric analysis; essential oil; ethnopharmacology; medicinal plants; neuropharmacology; phytochemistry; phytotherapy; traditional medicine
    DOI:  https://doi.org/10.3390/ph18030420
  58. F1000Res. 2025 ;14 92
    Applications of Machine Learning (ML) in the context of marketing: a bibliometric approach.
    Sebastián Cardona-Acevedo, Erica Agudelo-Ceballos, Diana Arango-Botero, Alejandro Valencia-Arias, Juana De La Cruz Ramírez Dávila, Jesus Alberto Jimenez Garcia, Carlos Flores Goycochea, Ezequiel Martínez Rojas.
      Currently, machine learning applications in marketing allow to optimize strategies, personalize experiences and improve decision making. However, there are still several research gaps, so the objective is to examine the research trends in the use of machine learning in marketing. A bibliometric analysis is proposed to assess the current scientific activity, following the parameters established by PRISMA-2020. Machine learning applications in marketing have experienced steady growth and increased attention in the academic community. Key references, such as Miklosik and Evans, and prominent journals, such as IEEE Access and Journal of Business Research, have been identified. A thematic evolution towards big data and digital marketing is observed, and thematic clusters such as "digital marketing", "interpretation", "prediction", and "healthcare" stand out. These findings demonstrate the continued importance and research potential of this evolving field.
    Keywords:  Artificial intelligence; Decision making; Digital marketing; PRISMA-2020.; Personalization
    DOI:  https://doi.org/10.12688/f1000research.160010.2
  59. J Contin Educ Health Prof. 2025 Mar 25.
    Measuring the Longitudinal Impact of a Health Professions Education Academy on Scholarship: A Bibliometric Analysis.
    Deborah L Engle, Elizabeth R Blackwood, Sarah Cantrell, Kristin L Dickerson, Diana B McNeill.
       ABSTRACT: Academies highlight the educational mission that is often second to clinical and basic science scholarship on health professions campuses. They help bridge the gap between faculty development and continuing professional development. Owing to their popularity, academies have proliferated across the United States and Canada during the past 3 decades. Yet the evidence of the extent to which academies have had impact on their organizations remains largely underdeveloped. In this article, the authors used logic modeling as a framework to align the research mission, programming, and longitudinal goals of the Duke Academy for Health Professions, Education and Academic Development across the span of a decade. Furthermore, we used bibliometric analysis as a program evaluation tool. Through three different case examples, we share how bibliometrics may be used to track faculty publications in health professions education journals and to assess the impact of an academy's investment on its members and the institution at large. Finally, we illustrate that longitudinal implementation of scholarship and grants programming can be an effective strategy for fostering the development of health professions education research and encouraging scholarly innovation.
    DOI:  https://doi.org/10.1097/CEH.0000000000000602
  60. J Taibah Univ Med Sci. 2025 Apr;20(2): 169-177
    Comprehensive bibliographic study of the framework of complex generic drugs.
    Amatha Sreedevi, Virendra S Ligade, Shailee Dewan.
       Background: Recently, extensive growth in bibliometric analysis has been observed. The demand for generic drugs has markedly increased in the past three decades, and the market appears to be saturated. Consequently, pharmaceutical companies are focusing on complex generics to improve patient demand and economic growth. This article highlights current research trends in generic and complex generic drugs through bibliometric analysis.
    Method: All documents from 2013 to 2023 associated with generics and complex generics were retrieved from the Scopus database. After application of the inclusion criteria, 144,015 articles on generics and 84 articles on complex generics were chosen for inclusion. Microsoft Excel and VOSviewer software were used to represent detailed studies and data on complex generics.
    Results: Publications associated with generic and complex drug products were identified, examined, compared, and summarized, to provide insights into trends and the future research scope. The number of obtained articles clearly indicated that the number of publications on generics is becoming saturated, whereas the number of complex generic studies is markedly increasing. The top regulated and semi regulated markets are now highly focused on complex generics. Concordantly, regulated markets such as those in the United States have funded more complex generics than simple generics. According to cluster analysis, studies on simple generics frequently focused on quality of life. In contrast, the clusters of studies on complex generics indicated challenges at various stages, thus shedding light on the growth of this field.
    Conclusion: This study provides a comprehensive bibliographic overview of the development of complex generic drugs and market growth. Researchers are currently more focused on complex generics than generics. A global revolution in pharmaceutical science can be expected if all stakeholder experts collaborate and focus on generic version of complex drugs.
    Keywords:  Bibliometric; Challenges; Cluster analysis; Quality of life; Regulations
    DOI:  https://doi.org/10.1016/j.jtumed.2025.02.013
  61. Ann Surg Open. 2025 Mar;6(1): e562
    A Metrology Informatics Investigation of Conversion Therapy in Hepatocellular Carcinoma: 2014-2023.
    Qi-Feng Chen, Xiong-Ying Jiang, Min-Shan Chen, Ning Lyu, Ming Zhao.
       Background: With advancements in drug therapy, local treatments, and evolving concepts, conversion therapy has shown benefits for patients initially diagnosed with unresectable hepatocellular carcinoma (HCC). Over the past 10 years, the conversion therapy field has accumulated a vast amount of underutilized data, necessitating in-depth bibliometric evaluation.
    Methods: This cross-sectional retrospective study collected a substantial amount of research on conversion therapy published between 2014 and 2023, adhering to strict search criteria. The primary outcomes were publication volume, citation count, and interstudy relationships. Comprehensive analysis was conducted using unsupervised hierarchical clustering, spatiotemporal analysis, regression model, and the Walktrap algorithm.
    Results: Over the past decade, conversion therapy has demonstrated significant progress, with an annual growth rate of 23.0%. Post-2020, these metrics saw a marked increase, reaching 116 publications and 1943 citations by 2023. Cluster analysis grouped 244 authors into 17 clusters, highlighting early and sustained contributions from Western authors compared with later-emerging Eastern authors. Research characteristics in HCC conversion therapy were classified into 5 clusters, with Cluster 2 (Target Therapy and Immunotherapy) emerging as a new focus. Thematic analysis categorized research characteristics into 4 quadrants, identifying "immune checkpoint inhibitor" and "combination therapy" as highly relevant and rapidly developing themes, while "hepatic arterial infusion chemotherapy" and "radioembolization" show high potential for future research.
    Conclusions: This study highlights key contributors and emerging trends and provides important predictions for future research directions. To achieve effective conversion therapy for HCC, researchers may prioritize immunotherapy and locoregional treatments such as hepatic arterial infusion chemotherapy or radioembolization.
    Keywords:  bibliometric analysis; combination therapy; conversion therapy; hepatocellular carcinoma; immunotherapy
    DOI:  https://doi.org/10.1097/AS9.0000000000000562
  62. Recent Adv Food Nutr Agric. 2025 Mar 24.
    Harnessing Artificial Intelligence for Sustainable Agriculture: A Comprehensive Scientometric Review.
    Hardeep Kaur, Bhanu Priya, Kuldeep Singh.
      Agriculture empowers the economies of most developing countries as it contributes to the GDP and provides employment to half of the population. To augment the functionalities of agriculture, Artificial Intelligence (AI) has emerged as a significant solution. Consequently, substantial research endeavours have been carried out in this direction lately. However, a com-prehensive study and scientometric analysis highlighting the potential of AI in agriculture has not been reported in the literature. Therefore, the presented scientometric study depicts the evolution of the pattern of research related to Artificial Intelligence technologies in agricultural practices based on the bibliographic data obtained from Scopus from 2015 to 2024. The data was analyzed and visualized using VOSviewer and Bibliometrix software by examining the publication growth trends, keyword co-occurrence networks, co-authorship networks, co-cita-tion networks, institutional coupling networks, and journal coupling networks. The presented research concluded that India excels in the field, contributing 874 research documents, a sub-stantial portion of the global total of 1,938. As per the link strength, China has secured the top position with 56 links and a total link strength of 1,080, while India follows closely in second place with 56 links and a total link strength of 871. The leading institution funding researchers with the highest number of publications is ICAR, while Science of the Total Environment stands out as the most relevant journal for disseminating their findings. The research topics explored involve using AI for disease detection, addressing nutrient deficiencies, analyzing soil content, and optimizing irrigation schedules. A notable emerging research topic highlights the effectiveness of AI in terms of increasing yield in agriculture. The future of AI in agricul-ture includes supply chain optimization, task automation, and climate adaptability, boosting food security and sustainability.
    Keywords:  Agriculture; artificial intelligence; disease detection; irrigation scheduling.; nutrient deficiency; scientometric analysis; soil content sensing
    DOI:  https://doi.org/10.2174/012772574X355955250212112211
  63. BMJ Open. 2025 Mar 25. 15(3): e092490
    Assessing the prevalence, quality and compliance of data-sharing statements in gastroenterology publications: a cross-sectional analysis.
    Jacksen Moore, Khanh Nguyen, Brody Dennis, Mahad Chaudhry, Annes Elfar, Eli Oldham, Eli Paul, Jacob Cohn, Alicia Ito Ford, Matthew Vassar.
       OBJECTIVE: To examine the current state of data-sharing practices in gastroenterology literature, focusing on data-sharing statements (DSS) and identifying influential factors on DSS inclusion.
    BACKGROUND: High-quality, reproducible research is crucial in addressing the widespread prevalence of gastrointestinal diseases. Data-sharing practices enable researchers to access studies more easily, enhancing reproducibility. Our study aims to analyse the inclusion and influence of DSS in top gastroenterology journals.
    METHODS: We conducted a cross-sectional analysis to examine the use and contents of DSS in gastroenterology clinical trials. Using Clarivate's Journal Citation Reports, we selected five leading gastroenterology journals. Then, we searched MEDLINE (PubMed) for original research articles published between 1 January 2018 and 31 December 2023. In a double-blind, duplicate manner, data were extracted on DSS presence, funding source, study design and open-access status. We then conducted a thematic analysis of all DSS. Additionally, authors were contacted and given 14 days to respond or share data to investigate adherence to their DSS.
    RESULTS: Of the 953 articles that met inclusion criteria, 400 (400/953; 42.0%) contained a DSS. Open-access articles had a higher likelihood of containing DSS (estimate=0·413; p<0.05). The Lancet Gastroenterology and Hepatology has the highest percentage of DSS (159/194; 82.0%), while Clinical Gastroenterology and Hepatology has the lowest percentage of DSS (33/256; 12.9%). Impact factor is a significant indicator for DSS (estimate=0.138, p=0.01). Finally, 'conditional data availability' was the most common data theme in our study (225/303; 74.3%). Over half (153/284; 53.9%) of the authors contacted did not respond to our request for sharing data.
    CONCLUSION: Our findings reveal significant variability in DSS inclusion and adherence among top gastroenterology journals. Journals with mandatory data-sharing policies demonstrated higher compliance, while open-access status and journal impact factor were positively associated with data-sharing practices. However, a notable gap remains in authors' follow-through on stated data-sharing commitments.
    Keywords:  GASTROENTEROLOGY; Information Storage and Retrieval; STATISTICS & RESEARCH METHODS
    DOI:  https://doi.org/10.1136/bmjopen-2024-092490
  64. Br Dent J. 2025 Mar 21.
    Evaluation of retracted publications related to oral health: a scoping review.
    Bodiek M L E Reith, Henk S Brand.
      Introduction Recent studies revealed high rates of questionable research practices and scientific misconduct among academic researchers. These practices may result in retraction of scientific publications. This scoping review aimed to analyse the characteristics of retracted publications with a focus on dental research.Methods To identify retracted articles in the field of dentistry, electronic searches were performed on PubMed Central, Web of Science, and the Retraction Watch website. Subsequently, data extraction was performed on identified relevant publications. Descriptive statistics were used to provide an overview of the characteristics of retracted scientific publications in dental research.Results The final dataset consisted of 333 retracted articles. The majority of these publications were written by authors from Asia (60.6%), particularly India (22.2%) and China (20.1%). More than half of the publications were retracted because of various forms of misconduct (57.4%), such as plagiarism, data duplication and data fabrication. Oral pathology was the subdiscipline in dentistry with the highest number of retracted publications (26.4%) and animal studies were the most prevalent study design among retracted publications (14.1%).Conclusions A large number of publications in dental research have been retracted during the past two decades, primarily to instances of scientific misconduct. Researchers, journal editors and academic institutions should prioritise the prevention and detection of misconduct to uphold the credibility and reliability of published dental literature.
    DOI:  https://doi.org/10.1038/s41415-024-8233-7
  65. BMC Med Educ. 2025 Mar 22. 25(1): 425
    An analysis of periodontology theses in Türkiye: Ph.D. vs. specialization program.
    Fatih Karayürek, Dicle Altindal, Erva Karayürek, Aydın Gülses.
       BACKGROUND: The cross-sectional study aimed to compare and evaluate the conversion rates of theses and dissertations of Ph.D. and specialization programs of the periodontology department in Türkiye.
    METHODS: A total of 789 theses of dentists who successfully graduated from higher education institutions in Türkiye between 2001 and 2020 and qualified to become specialist dentists were analyzed. In these analyses, after descriptive information, the status of the theses converted into publications, the duration of publication, the number of citations, the indexes of the journals, and the employment status of dentists in the academy after graduation were evaluated. The Shapiro-Wilks test and Kolmogorov-Smirnov test were applied for the normality test. A chi-square test was used for categorical variables. Independent T-test, Mann-Whitney U test, Kruskal-Wallis test, and time series linear regression test were applied.
    RESULTS: 336 Ph.D. (60.54%) and 110 (47%) dentists in specialty programs had their theses translated for publication (p = 0.001). 242 Ph.D. dentists (72.02%) published their thesis in an SCI-Expanded journal, while only sixty-nine specialty dentists (62.7%) published in these journals (p = 0.001). The publications of dentists with Ph.D. in SCI-Expanded indexed journals were mostly in journals ranked Q1 and Q2, while those of dentists with specialization were in journals ranked Q3 and Q4 (p = 0.012). The publications of dentists with Ph.D. received an average of 24 citations on the Web of Science, while those of specialists received seven (p = 0.001).
    CONCLUSIONS: The decline in the conversion of the theses of dentists graduating from the specialty program into publications may impact the field of periodontology in Türkiye. More comprehensive studies are needed to evaluate the effectiveness of the specialty program.
    Keywords:  Health policy; Ph.D.; Publishing; Specialty program; Thesis
    DOI:  https://doi.org/10.1186/s12909-025-06997-z
  66. Antibiotics (Basel). 2025 Feb 27. pii: 242. [Epub ahead of print]14(3):
    The Significance of Probiotics in Aquaculture: A Review of Research Trend and Latest Scientific Findings.
    Elshafia Ali Hamid Mohammed, Abdelhakam Esmaeil Mohamed Ahmed, Béla Kovács, Károly Pál.
      Millions of people around the world rely on aquaculture as a major source of food. In the recent few years, probiotics have gained considerable attention as an alternative agent to antibiotics. They have been shown to play an important role in improving aquaculture species through different mechanisms, mainly disease management, improving their growth performance, and improving water quality. Consequently, this review aimed to identify the key areas of research in the global literature about the influence of probiotics on aquaculture based on the selected keywords "aquaculture" AND "probiotics" AND "growth performance" AND "disease resistance" (APGD). The meta-data of the published literature were extracted from the Web of Science (WoS) database on 23 December 2024, and then the co-authors, countries, and keywords were analyzed and visualized using VOSviewer (v. 1.6.20). The search found a remarkable number of documents, which included 175 APGD documents. The results of the bibliometric analysis of the global literature reveal a substantial increase in the publication of APGD documents from 2019 to 2024. Asia, particularly China (32.3% of documents), has emerged as a leader of APGD publications, followed by Iran (8.67%), India (8.01%), Malaysia (7.5%), and Spain (7.5%), respectively. Keyword analysis revealed the prevalence of disease resistance (length = 1793), probiotics (1348), aquaculture (1169), and growth performance (913) as the most impactful keywords based on the WoS database. This could indicate that most of the APGD documents were focused on disease resistance and probiotics relationships. In addition, an extensive review of the recent literature showed that probiotics have demonstrated a remarkable efficacy in improving the growth performance, feed utilization efficiency, disease prevention, and water quality management in various aquaculture species under different aquaculture systems when used as feed or water additives for 30-90 days. It can be concluded that Asia is the lead continent in aquaculture probiotics research, with a significant increase in APGD documents in the last 5 years. Probiotics played a major role in improving aquatic species. This research aims to provide valuable insight into the use of probiotics in aquaculture and highlights the need for further research to fully understand their benefits and mechanisms of action.
    Keywords:  VOSviewer; antibiotics; aquaculture; bibliometric analysis; disease resistance; growth performance; probiotics
    DOI:  https://doi.org/10.3390/antibiotics14030242
  67. Neurosci Res. 2025 Mar 21. pii: S0168-0102(25)00052-5. [Epub ahead of print]
    The parental brain: Anatomization of 75 years of neuroscience 1951-2024.
    Alessandro Carollo, Lucrezia Torre, Marc H Bornstein, Gianluca Esposito.
      Studies of the parental brain have garnered significant attention, revealing neurobiological and psychological changes associated with caregiving. Here, we provide a comprehensive, data-driven overview of the scientific literature on the parental brain, analyzing a large dataset to map the field's knowledge structure. Our objectives include identifying influential authors, contributing countries, publication sources, and commonly used keywords as well as highlighting the most impactful documents and primary thematic areas of research. We analyzed 656 documents (and their 39,302 cited references) from Scopus using CiteSpace software for document co-citation analysis. Our analysis identified 17 key documents, of which the most influential focused on neural correlates of maternal and romantic love and maternal brain responses to infant cues in relation to attachment style. Our analysis additionally identified 10 major thematic domains in the parental brain literature. Qualitative analysis of research clusters revealed a trajectory in the study of the parental brain, progressing from foundational studies on dendritic spine density and maternal memory to the exploration of shared mammalian and human-specific brain networks underlying parental behaviors. Our study points to a growing interest in understanding neurobiological changes in fathers, with parental involvement and exposure to infant cues as moderating factors. The parental brain is a plastic, dynamic network, with bio-behavioral synchrony playing a central role as an interpersonal mechanism that enhances specificity of attachments.
    Keywords:  Attachment; Fatherhood; Motherhood; Parental brain; Parenting; Scientometrics
    DOI:  https://doi.org/10.1016/j.neures.2025.03.002
  68. Cell Transplant. 2025 Jan-Dec;34:34 9636897251325628
    Bibliometric and LDA analysis of acute rejection in liver transplantation: Emerging trends, immunotherapy challenges, and the role of artificial intelligence.
    Liqing Jiang, Jie Wang, Yihua Wang, Hang Yang, Lingwang Kong, Zhongjun Wu, Ai Shen, ZuoTian Huang, Yingsong Jiang.
      With the rising demand for liver transplantation (LT), research on acute rejection (AR) has become increasingly diverse, yet no consensus has been reached. This study presents a bibliometric and latent Dirichlet allocation (LDA) topic modeling analysis of AR research in LT, encompassing 1399 articles. The United States, Zhejiang University, and the University of California, San Francisco emerged as leading contributors, while Levitsky J and Uemoto SJ were key researchers. The most influential journals included the American Journal of Transplantation, Journal of Hepatology, and Transplantation. The analysis reveals a transition from traditional histological assessments to molecular diagnostics, genetic and epigenetic profiling, and noninvasive biomarkers such as donor-derived cell-free DNA (dd-cfDNA) and microRNAs. Advances in immune checkpoint inhibitors (ICIs), cell-based therapies (Tregs, mesenchymal stem cells (MSCs)), AI-guided immunosuppression, and nanoparticle-mediated drug delivery systems reflect a growing emphasis on precision medicine. In addition, recent exploration of microbiome-based therapies and regenerative medicine, including MSCs and their extracellular vesicles, offers promising new avenues for reducing long-term immunosuppressive drug dependency and enhancing graft survival. These developments not only improve early AR detection and personalized treatment but also reduce toxicity, foster immune tolerance, and expand the scope of individualized therapeutic options. Global collaboration, supported by cutting-edge research and AI-driven decision-making, remains essential for refining AR strategies, improving graft survival, and achieving better long-term patient outcomes.
    Keywords:  acute rejection; bibliometric analysis; latent Dirichlet allocation; liver transplantation
    DOI:  https://doi.org/10.1177/09636897251325628
  69. J Forensic Leg Med. 2025 Mar 18. pii: S1752-928X(25)00055-1. [Epub ahead of print]111 102854
    Mapping the landscape: Analysis of publication trends in forensic anthropology. Insights from Poland.
    Melania Mazur, Agata Cieślik, Katarzyna Górka.
      Academic research in forensic anthropology is a crucial aspect for the development of this highly applied science, especially considering its social impact. The interdisciplinary character of forensic anthropology and very diversified caseload create a context in which theoretical and practical challenges emerge. This requires a swift response from the scientific community to develop new solutions or improve existing approaches. Although much is being produced worldwide in the field of forensic anthropology, there are only a few countries that lead this trend. In this article, the authors attempted to critically examine academic research within forensic anthropology in Poland by analysing its knowledge production over the last decades. A meticulous bibliographic analysis resulted in the discovery of 220 relevant academic records published between 1952 and 2023. Almost 70 % of identified papers were published in national journals and 58 % appeared in Polish. In total, 36 different institutions participate in knowledge production in this field. International collaboration is very low (∼6 %) and over 50 % of records did not involve any academic partnership. The most common type of paper is case report, primarily related to mass grave exhumations of war and totalitarian crimes. We conclude that Polish forensic anthropology research is derivative rather than original (with case reports and review papers as most frequent) and Poland remains a relatively insignificant actor when considering the overall knowledge production in forensic anthropology. In the discussion we try to understand these outcomes in the light of Polish historical context and current academic, and socio-political conjuncture.
    Keywords:  Academic development; Academic publications; Bibliographic search; Challenges; Forensic anthropology; Research
    DOI:  https://doi.org/10.1016/j.jflm.2025.102854
  70. Glob Epidemiol. 2025 Jun;9 100192
    An overview of reviews of breastfeeding barriers and facilitators: Analyzing global research trends and hotspots.
    Agustín Ramiro Miranda, Paula Eugenia Barral, Ana Veronica Scotta, Mariela Valentina Cortez, Elio Andrés Soria.
      Breastfeeding is the most cost-effective intervention for reducing infant morbidity and mortality, offering benefits for infants and mothers. Despite extensive promotion, global adherence remains below 50 %, resulting in significant clinical, economic, and environmental impacts. Thus, this overview of reviews aims to synthesize barriers and facilitators of breastfeeding, analyze research trends, and identify gaps to guide future research. A comprehensive literature search was conducted, including systematic reviews that examine these factors. The search covered seven electronic data repositories. The methodological quality was assessed using the Risk of Bias in Systematic Reviews tool. Bibliometric analysis focused on identifying top journals, authors, and countries, assessing their impact, and exploring trends over time. Findings were classified and analyzed thematically through line-by-line coding, theme description, and analytical formulation. A total of 123 reviews were included, mostly of high quality and published in top journals. Key trends comprised a growing focus on psychosocial and cultural factors, increased representation from low- and middle-income countries, and improved methodological rigor. However, geographical representation remains biased towards high-income countries, and some breastfeeding outcomes need further exploration. Thematic analysis revealed four categories: Therapeutic and care interventions; Support networks and education; Maternal-infant health issues; and Societal and environmental context. In conclusion, this overview of reviews identifies barriers and facilitators of breastfeeding and emphasizes the need for more inclusive research and tailored support. Addressing gaps in evidence for enhancing healthcare systems and policies can improve breastfeeding practices and outcomes worldwide.
    Keywords:  Barriers; Bibliometrics; Breastfeeding; Facilitators; Lactation; Research trends; Science mapping
    DOI:  https://doi.org/10.1016/j.gloepi.2025.100192
  71. South Asian J Cancer. 2025 Jan;14(1): 1-3
    Technology and Innovation Has Made Impact Factor Redundant-Better Alternatives Are Here to Thrive.
    Purvish M Parikh, Amish Vora.
      
    DOI:  https://doi.org/10.1055/s-0043-1767699
  72. Behav Sci (Basel). 2025 Mar 20. pii: 395. [Epub ahead of print]15(3):
    Sensory Processing Measure and Sensory Integration Theory: A Scientometric and Narrative Synthesis.
    Hind M Alotaibi, Ahmed Alduais, Fawaz Qasem, Muhammad Alasmari.
      Sensory integration theory (SIT), which posits that the neurological process of integrating sensory information from the environment and one's body influences learning and behaviour, and the sensory processing measure (SPM), a psychometric tool with versions for individuals aged 4 months to 87 years, are fundamental to understanding and assessing sensory processing. This study examined the existing evidence on the SPM and SIT using scientometric and narrative methods. A search of Scopus and Web of Science Core Collection from 1983 to 2024 yielded 238 unique records after deduplication. Scientometric analysis, conducted with CiteSpace (Version 6.4.R1) and VOSviewer (Version 1.6.19) explored publication trends, keyword co-occurrences, and citation bursts. A narrative method, based on a purposive sample of studies selected by title relevance from the 238 records, provided qualitative insights into key themes and concepts. Scientometric analysis revealed 11 key clusters, including 'sensory processing behaviour', 'classroom context', and 'using electroencephalogram (EEG) technology', reflecting diverse research areas and a growing publication trend, particularly after 2011. A narrative analysis, guided by these clusters, explored sensory processing differences in children with developmental disorders like autism spectrum disorder (ASD) compared to typically developing children, the relationship between sensory processing and other functional areas, the impact of classroom contexts on sensory processing, the use of EEG in sensory processing disorder (SPD) diagnosis, and the effectiveness of interventions like sound-based therapy and sensory integration therapy. The combined approach highlighted the wide application of the SPM and SIT, informing future research directions, such as longitudinal studies, comparative effectiveness research, and cultural adaptations of assessments and interventions.
    Keywords:  narrative synthesis; occupational therapy; scientometric synthesis; sensory integration theory; sensory processing disorder; sensory processing measure
    DOI:  https://doi.org/10.3390/bs15030395
  73. Arch Dermatol Res. 2025 Mar 27. 317(1): 640
    Mendelian randomization in the discovery of risk factors for autoimmune skin diseases: a bibliometric and visualized analysis.
    Caiqin Mao, Lisheng Nan, Jianhua Bu, Xianwei Wu.
      
    DOI:  https://doi.org/10.1007/s00403-025-04171-5
  74. J Natl Med Assoc. 2025 Mar 24. pii: S0027-9684(25)00022-7. [Epub ahead of print]
    The impact of NIH funding and program reputation score on research output and residency matches in neurosurgery: A bibliometrics analysis.
    Kyril L Cole, Ashley Carter, Clayton Rawson, Sam Tenhoeve, Cody Orton, Maryam Zeinali, Michael Karsy.
      The neurosurgery residency applicant selection process is complex, with peer-reviewed publications (PRP) recently becoming a key focus. While PRP may significantly impact applicant matching, equitable opportunities for research may vary for students. We aimed to evaluate the impact of NIH funding and program reputation score on applicants' ability to match into top neurosurgery residency programs. Successfully matched PGY1 neurosurgery applicants in the 2022-2023 cycle were evaluated. PRP, Blue Ridge Institute for Medical Research (BRIMR) medical school and residency NIH-funding ranking, and residency Doximity reputation score were evaluated. PGY1 residents (n = 235, 73% male) included 84% MDs, 1.0% DO, 10% MD/PhD, and 5% IMGs. Thirty-one (13.2%) superpublishers (> 25 PRPs) were identified (93.5% male) and had a higher number of non-MD degrees (32.3% vs. 13.3%, p = 0.007). Matching into a top 20 NIH-ranked residency program was associated with completion of a top 20 NIH-medical program (OR = 2.70, p = 0.015), superpublisher status (OR = 2.87, p = 0.024), and affiliation with a top 40 NIH-ranked neurosurgery program (OR = 3.44, p < 0.001). Matching into a top 40 reputation program was predicted by being a superpublisher (≥ 25 publications; OR = 2.66, p = 0.04) and attending a medical school with an affiliated top 40 reputation neurosurgery program (OR = 4.85, p < 0.001). PRP has become a large focus in determining a candidate's competitiveness for top neurosurgery residency programs. Our results clarify the factors impacting PRP, including the importance of NIH funding and the neurosurgery department's reputation. These results highlight both best practices for training residents and potential disadvantages some medical school candidates may have from lower-ranked programs or limited research opportunities. Further studies are warranted to evaluate the impact of these factors on the equity of neurosurgery residency candidates.
    Keywords:  Matching; Mentorship; Neurosurgery; Productivity; Research; Residency
    DOI:  https://doi.org/10.1016/j.jnma.2025.03.002
  75. Am J Pharm Educ. 2025 Mar 25. pii: S0002-9459(25)00043-9. [Epub ahead of print] 101398
    Impact of COVID-19 on Scholarly Outcomes of Pharmacy Practice Faculty by Gender and Academic Rank.
    Samuel O Adeosun, Ayonna M Hollowell, Olalekan Soremekun.
       OBJECTIVE: To determine how the COVID-19 pandemic impacted the scholarly outcomes of pharmacy practice faculty, and whether the impact varied by gender and academic rank.
    METHODS: Pharmacy practice faculty from the top 50 NIH-funded schools of pharmacy (2018-2021) were included. Faculty whose gender was indeterminable with Gender API or who has no Scopus record were excluded. Publications before and during the pandemic (2018-2019 and 2020-2021, respectively) were obtained from Scopus. Primary outcomes included scholarly activity (probability of publishing) and scholarly output (number of documents published). Secondary outcomes were fractional scholarly output (FSO) and collaboration coefficient (CC). Data was analyzed using generalized linear mixed-effects models, with fixed effects including pandemic, rank, and gender. Interaction effects were only included in final models if statistically significant.
    RESULTS: Faculty included were 1081 (61.2% women; 31.4%, 40.0%, and 28.7% assistant, associate, and professors, respectively). Unique documents published increased from 2428 to 2737 during the pandemic. There was a significant pandemic-rank interaction in scholarly activity, while scholarly output had both pandemic-rank and pandemic-gender interactions. Men had higher scholarly output versus women across all ranks, in both periods. During the pandemic, scholarly output increased among all assistants and associates, but among professors, men had no change, while women had a decrease.
    CONCLUSION: The pandemic effect on pharmacy practice faculty scholarly outcomes varied across gender and academic ranks. Institutions should implement initiatives to mitigate the extant gender gap in scholarly output that persisted during the pandemic, as it may impact career progression, tenure prospects, and retention.
    Keywords:  Academic rank; COVID-19; Gender; Pharmacy practice; Productivity
    DOI:  https://doi.org/10.1016/j.ajpe.2025.101398
  76. Medicine (Baltimore). 2025 Mar 21. 104(12): e41749
    Mapping intellectual structure and research hotspots of cancer studies in primary health care: A machine-learning-based analysis.
    Muhammet Damar, Hale Turhan Damar, Şeyda Özbiçakci, Gökben Yasli, Fatih Safa Erenay, Güzin Özdağoğlu, Andrew David Pinto.
      In the contemporary fight against cancer, primary health care (PHC) services hold a significant and critical position within the healthcare system. This study, as one of the most detailed investigations into cancer research in primary care, comprehensively evaluates cancer studies from the perspective of PHC using bibliometric techniques and machine learning. The dataset for the analyses was sourced from the Web of Science (WoS) Core Collection database on March 20, 2024. The Bibliometrix package within the R programming environment, alongside the Biblioshiny application, and VOSViewer software were employed for the bibliometric analyses. In this study, Latent Dirichlet Allocation was utilized as a prominent topic modeling algorithm. The implementation of this technique utilized Python along with the SciKit-Learn and Gensim libraries, ensuring robust model development and evaluation. The 2040 articles were produced by a total of 6705 different authors, 2166 different affiliations, and 75 different countries. Cancer survivors are more vulnerable and need more sensitive health services. The most intensively studied 3 cancer types in the PHC, listed by prevalence, are colorectal cancer, breast cancer, and cervical cancer. Additionally, prominent research topics in PHC include cancer screening, diagnosis, early detection, prevention, education, genetic factors and family history, risk factors, symptoms/signs, preventive medicine, referral and consultation, chronic disease management and health services research for cancer patients, health care disparities, palliative care, and communication with patients in PHC. Family physicians, being the first point of contact with the public, play a crucial role in preventing cancer cases, caring for patients with active cancer diagnoses, supporting cancer survivors in their post-cancer lives, and identifying and referring cancer cases at the earliest stages. However, cancer has many types, each with its own distinct symptoms, as well as similar types to each other. At this point, periodic educational training for doctors on cancer by health authorities, regular publication of cancer-related guidance resources by the central healthcare system, development of integrated decision support tools used by physicians during patient care, and the creation of informative mobile applications for cancer prevention or post-cancer life for patients have been considered highly critical.
    DOI:  https://doi.org/10.1097/MD.0000000000041749
  77. Account Res. 2025 Mar 25. 1-25
    Formalistic data and code availability policy in high-profile medical journals and pervasive policy-practice gaps in published articles: A meta-research study.
    Wei Li, Xuerong Liu, Qianyu Zhang, Liping Shi, Jing-Xuan Zhang, Xiaolin Zhang, Jia Luan, Yue Li, Ting Xu, Rong Zhang, Xiaodi Han, Jingyu Lei, Xueqian Wang, Yaozhi Wang, Hai Lan, Xiaohan Chen, Yi Wu, Yan Wu, Lei Xia, Haiping Liao, Chang Shen, Yang Yu, Xinyu Xu, Chao Deng, Pei Liu, Zhengzhi Feng, Chun-Ji Huang, Zhiyi Chen.
       BACKGROUND: Poor data and code (DAC) sharing undermines open science principles. This study evaluates the stringency of DAC availability policies in high-profile medical journals and identifies policy-practice gaps (PPG) in published articles.
    METHODS: DAC availability policies of 931 Q1 medical journals (Clarivate JCR 2021) were evaluated, with PPGs quantified across 3,191 articles from The BMJ, JAMA, NEJM, and The Lancet.
    RESULTS: Only 9.1% (85/931) of journals mandated DAC sharing and availability statements, with 70.6% of these lacking mechanisms to verify authenticity, and 61.2% allowing publication despite invalid sharing. Secondary analysis revealed a disproportionate distribution of policies across subspecialties, with 18.6% (11/59) of subspecialties having >20% journals with mandated policies. Journal impact factors exhibited positive correlations with the stringency of availability statement policies (ρ = 0.20, p < 0.001) but not with sharing policies (ρ = 0.01, p = 0.737). Among the 3,191 articles, PPGs were observed in over 90% of cases. Specifically, 33.7% lacked DAC availability statements, 23.3% refused sharing (58.4% of which without justification in public statements), and 13.5% declared public sharing, with 39.0% being unreachable. Finally, only 0.5% achieved full computational reproducibility.
    CONCLUSIONS: Formalistic policies and prevalent PPGs undermine DAC transparency, necessitating a supportive publication ecosystem that empowers authors to uphold scientific responsibility and integrity.
    Keywords:  Data and code; availability; journal policy; open science; policy-practice gap
    DOI:  https://doi.org/10.1080/08989621.2025.2481943
  78. Front Vet Sci. 2025 ;12 1394675
    Research publications and global manufacture of veterinary vaccines against avian influenza A (2019-2023).
    Aníbal Domínguez-Odio, Ernesto Rodríguez-Martínez, Mayelin Paneque Zayas, Daniel Leonardo Cala-Delgado.
      The characteristics of the avian influenza virus and its worldwide spread have led to intense and unprecedented scientific activity and industrial production for preventive veterinary vaccines. However, knowledge gaps remain regarding the best strategies to prevent epidemiological events in the future. In this context, the present study aimed to provide a global analysis on the scientific and industrial production of avian influenza type A vaccines for farm animals and pets during the period 2019 2023. The Scopus database was used as the primary source of information (12,162 keywords, 2,437 scientific articles, 659 academic journals, and 46 countries) for the academic analysis, while technical information posted on official institutional websites (136 commercial formulations, 24 vaccines manufacturers, and 17 countries) was collected to conduct the industrial analysis. 3,045, 25.0%) exhibited the highest levels of co-occurrence in the sciences; the journal Vaccine was the most productive in terms of articles (11.8%, 288/2,437), and the countries with the most publications were the USA (25.5%, 622/2,437) and China (23.1%, 564/2,437). The most internationally marketed vaccines were inactivated (86.0%, 117/136), avian (47.1%, 64/136), and combined (52.2%, 71/136) vaccines as well as those containing Newcastle antigens (38.0%, 27/71). In conclusion, the study demonstrated the fundamental role of classical production methods (based on the use of the whole pathogen) in avian influenza A research and the production of veterinary vaccines.
    Keywords:  Avian influenza virus; adjuvant; livestock; pets; strain; technological surveillance; vaccine
    DOI:  https://doi.org/10.3389/fvets.2025.1394675
  79. Nature. 2025 Mar;639(8056): 838
    Track gender ratios in research to keep countries, institutions and publishers accountable.
      
    Keywords:  Institutions; Scientific community; Society
    DOI:  https://doi.org/10.1038/d41586-025-00891-w
  80. Arch Public Health. 2025 Mar 21. 83(1): 74
    Research trends in pediatric diseases in North Korea: a scoping review of North Korean medical journals, 2006-2019.
    I Re Lee, Hae Won Lee, Hanna Jung, Songyi Han, Shinki An, Woo Taek Jeon.
       BACKGROUND: This study analyzed the status of research trends in pediatric diseases in North Korea, as reported in North Korean medical journals. Despite the censorship and control exerted by the North Korean government, these journals provide critical insights into practical achievements and disease cases, serving as vital data sources for understanding North Korea's health landscape.
    METHODS: We reviewed 10 North Korean medical journals published from 2006 to 2019, specifically targeting the journals Pediatrics, Obstetrics and Gynecology; Surgery; and Chosun Medicine. From an initial pool of 7,739 articles, 728 pediatric research articles were selected for in-depth analysis. We categorized the articles according to publication year, field, article type, research method, statistical approach, and content. Pediatric diseases were classified using the International Classification of Diseases, Tenth Revision. We additionally investigated temporal changes, particularly between the Kim Jong-il and Kim Jong-un eras.
    RESULTS: Our analysis of pediatric research articles from North Korean medical journals demonstrated a consistent format and brevity, with the frequent inclusion of the ruling authority's directives and a lack of ethical discussion. Notably, epidemiological studies and randomized controlled trials were not reported. The research focused instead on practical applications, addressing high-burden diseases and the therapeutic effects of traditional medicines. Our distribution analysis revealed that congenital malformations (16.2%), infectious diseases (12.6%), respiratory diseases (11.2%), and gastrointestinal diseases (10.9%) were the most frequently studied topics, reflecting the primary causes of pediatric mortality in North Korea. A significant increase in the volume and diversity of pediatric research was observed during the Kim Jong-un era, coinciding with improved economic conditions and an increased emphasis on science and technology policies.
    CONCLUSIONS: North Korean pediatric research exhibits distinct and practical characteristics, with trends of increasing diversity and volume over time. Our findings highlight the ongoing autonomous development of pediatric medicine in North Korea, which could have positive implications for future pediatric research in the country. Understanding these research trends is essential for developing strategies to improve children's health in North Korea.
    Keywords:  Medical journal; North Korea; Pediatric research; Research trends
    DOI:  https://doi.org/10.1186/s13690-025-01547-x
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