bims-evares Biomed News
on Evaluation of research
Issue of 2025–03–16
77 papers selected by
Thomas Krichel, Open Library Society
  1. Global research trends on the human exposome: a bibliometric analysis (2005-2024).
  2. Global Research on the Treatment of Cancer Patients During the COVID-19 Pandemic: Visualisation and Bibliometric Analysis.
  3. Standardized patient simulation in nursing education: A bibliometric analysis and visualization from 2002 to 2024.
  4. Bibliometric Indexes - Advantages and Limitations in Practical Application, for the Scientific Validity of Authors and Their Scientific Contents - Stanford Bibliometric List: Truths and Misconceptions.
  5. Unstable thoracolumbar injuries: A bibliometric analysis of the most influential papers.
  6. A bibliometric analysis of the advance of artificial intelligence in medicine.
  7. Clear aligners: A network and bibliometric analysis of 50 pivotal articles.
  8. Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis.
  9. Global research trends and hotspots in mitochondria and asthma: A bibliometric and visualized analysis.
  10. Knee Society Members Are High Impact Researchers in the Field of Knee Arthroplasty: A Quantitative Analysis.
  11. Trends in noninvasive ocular nanoparticle drug delivery: A bibliometric analysis (2004-2023).
  12. A bibliometric analysis of perioperative rehabilitation research between 2005 and 2024.
  13. Bibliometric analysis of cognitive dysfunction after traumatic brain injury.
  14. A Bibliometric Analysis of the Top 100 Most-Cited Articles on Skin Photoaging.
  15. Trends in Physical Activity Research on Tobacco and/or Alcohol: A Bibliometric Analysis.
  16. Knowledge structure and dynamic evolution of nanomedicine in liver cancer research: a scientometric analysis and visualization.
  17. Global trends and hotspots of neuromodulation in spinal cord injury: a study based on bibliometric analysis.
  18. Knowledge mapping and research trends of cathelicidin peptide LL-37 from 1995 to 2024: a bibliometric study.
  19. Global research trends on chronic thromboembolic pulmonary hypertension: a bibliometric analysis (January 2000-January 2024).
  20. Pulsed field ablation for atrial fibrillation: a comprehensive bibliometric analysis of research trends and emerging Frontiers.
  21. Bibliometric analysis: a study of the microenvironment in cervical cancer (2000-2024).
  22. A bibliometric analysis of research hotspots and trends in transcranial magnetic stimulation and Alzheimer's disease.
  23. The 100 most-cited radiomics articles in cancer research: A bibliometric analysis.
  24. A Bibliometric Analysis of the Application of Brain-Computer Interface in Rehabilitation Medicine Over the Past 20 Years.
  25. Mapping the Knowledge Landscape of and Emerging Future Trends in Stem Cell Therapy for Osteoarthritis: A Bibliometric Analysis of the Literature From 1998 to 2024.
  26. Research trends and highlights in PD-1/PD-L1 inhibitor immunotherapy in lung cancer: a bibliometric analysis.
  27. Global research trends in the intestinal microflora and depression: bibliometrics and visual analysis.
  28. Research status and hotspots of hypothermia and human diseases: a bibliometric analysis.
  29. Bibliometrics of gastric cancer prediction models.
  30. Nutritional therapy in palliative care units: A bibliometric analysis.
  31. Bibliometrics and National Institutes of Health Funding: Associated Factors in Academic Rhinology.
  32. Six Decades of Scientific Output: A Bibliometric Analysis of Research Contributions from the National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez".
  33. Bibliometric analysis of high-fidelity simulation training in nursing.
  34. Mapping Global Scientific Production on Human Immunodeficiency Virus and Monkeypox: A Scientometric Study.
  35. Mapping the evolution of anti-diabetic polysaccharides research: Trends, collaborations, and emerging frontiers.
  36. Bibliometric and visual analysis in the field of electroacupuncture's analgesia and regulation on negative emotion from 2014 to 2024.
  37. Three Decades of Photodynamic Therapy for Glioblastoma: A Comprehensive Scientometric Analysis.
  38. Depression and Anxiety in Patients with Psoriasis: A Comprehensive Analysis Combining Bibliometrics, Latent Dirichlet Allocation, and HJ-Biplot.
  39. Scientometric Mapping of the Flipped Classroom in Dental Education: Geospatial Dynamics, Emergent Patterns, and Networking.
  40. Analysis of research trends and hot spots on COPD biomarkers from the perspective of bibliometrics.
  41. Therapeutic potential of triple-negative breast cancer immune checkpoint blockers: A 21-year bibliometric analysis.
  42. The Effect of Leisure-Time Exercise on Mental Health Among Adults: A Bibliometric Analysis of Randomized Controlled Trials.
  43. Emerging trends and hotspots in animal experimental research on lung transplantation from 2004 to 2023: a bibliometric analysis.
  44. Do manuscripts by female evolutionary biologists spend longer under review?
  45. A Bibliometric Analysis of Sitting Position and Air Embolism in Neurosurgery: Top 100 Most Cited Articles.
  46. Knowledge map and emerging trends of oxidative stress in wound healing: A bibliometric analysis from 2000 to 2023.
  47. Scientometric Study of Mpox and Vaccine Research: Dynamics, Emerging Patterns, and Networking.
  48. Exploring socio-economic dimensions in HIV research: a comprehensive bibliometric analysis (1992-2024).
  49. Global scientific research landscape on binge drinking: a comprehensive bibliometric and visualization analysis of trends, collaborations, and future directions.
  50. Bibliometric and visualisation analyses of gastric ulcer knowledge areas and emerging trends, 2004-2024.
  51. The association between obstructive sleep apnea and nocturnal enuresis in children: current advances and research trends.
  52. Research productivity among applicants who matched into an integrated thoracic surgery residency program: A bibliographic review.
  53. Bibliometrics of the Dental Implant Literature: Journals, Countries, and Top-Cited Papers.
  54. Evolving paradigms in prostate cancer screening: a decade of bibliometric insights and technological advancements.
  55. Mapping nine decades of research integrity studies (1935-2024): A scientometric analysis.
  56. The impact of salinity on heavy metal accumulation in seaweed.
  57. Mapping Research Trends in Alcoholic Liver Disease: A Bibliometric Perspective.
  58. Mapping the landscape of vitamin D in cancer studies: a systematic global investigation.
  59. [Bibliometric Study and Network Mapping of Teacher Technostress Between 1992-2022].
  60. Cranberry-derived bioactives for the prevention and treatment of urinary tract infections: antimicrobial mechanisms and global research trends in nutraceutical applications.
  61. Gender imbalance in critical care medicine journals.
  62. National Institute of Academic Anaesthesia (NIAA) research grants: analysis of awardee characteristics and preliminary grant outputs.
  63. The Use of Synthetic Dermal Matrix in Lower Eyelid Reconstruction: Our Surgical Management and a Bibliometric and Visual Analysis.
  64. Investigating the Impact of Resident Doctor Regional Research Meetings on Research Outcomes: A 20-Year Longitudinal Analysis of the Regional Bardhan Fellowship Day.
  65. Hotspot Analysis of Rumen Microbiota and Methane Mitigation in Ruminants: A Bibliometric Analysis from 1998 to 2023.
  66. Two Decades at 21%: Unchanging Gender Disparities in Rhinology Fellowships.
  67. Retractions in Otolaryngology Publications.
  68. Leaving science-attrition of biologists in 38 OECD countries.
  69. The Limited Impact of Randomized Controlled Trials on the Management of Greater Trochanteric Pain Syndrome as Demonstrated by Fragility Indices: A Citation Analysis.
  70. Abstracts to articles: Examining the publication of presentations at the New Zealand Association of Plastic Surgeons Annual Scientific Meetings.
  71. Representation of women in scientific subjects: overview of systematic reviews investigating career progress in academic publishing with a focus on mental health.
  72. Gender trends at the annual meetings of two major Japanese societies of sports medicine: a 17-year summary of annual meeting moderators and speakers.
  73. Gender equality among medical and dental academic researchers in West Africa: a theoretical analysis of a compendium of research.
  74. Gender Composition of Invited Speakers and Session Chairs at American Society for Apheresis Annual Meetings Between 2019 and 2024.
  75. How a PhD student's lab size affects their chance of future academic success.
  76. Differences in NIH Funding, Publications, and H-Index between Men and Women Who Are Endowed Dermatology Chairs.
  77. AI tools are spotting errors in research papers: inside a growing movement.
  1. Environ Sci Pollut Res Int. 2025 Mar 08.
    Global research trends on the human exposome: a bibliometric analysis (2005-2024).
    Pascal Petit, Nicolas Vuillerme.
      Exposome represents one of the most pressing issues in the environmental science research field. However, a comprehensive summary of worldwide human exposome research is lacking. We aimed to explore the bibliometric characteristics of scientific publications on the human exposome. A bibliometric analysis of human exposome publications from 2005 to December 2024 was conducted using the Web of Science in accordance with PRISMA guidelines. Trends/hotspots were investigated with keyword frequency, co-occurrence, and thematic map. Sex disparities in terms of publications and citations were examined. From 2005 to 2024, 931 publications were published in 363 journals and written by 4529 authors from 72 countries. The number of publications tripled during the last 5 years. Publications written by females (51% as first authors and 34% as last authors) were cited fewer times (13,674) than publications written by males (22,361). Human exposome studies mainly focused on air pollution, metabolomics, chemicals (e.g., per- and polyfluoroalkyl substances (PFAS), endocrine-disrupting chemicals, pesticides), early-life exposure, biomarkers, microbiome, omics, cancer, and reproductive disorders. Social and built environment factors, occupational exposure, multi-exposure, digital exposure (e.g., screen use), climate change, and late-life exposure received less attention. Our results uncovered high-impact countries, institutions, journals, references, authors, and key human exposome research trends/hotspots. The use of digital exposome technologies (e.g., sensors, and wearables) and data science (e.g., artificial intelligence) has blossomed to overcome challenges and could provide valuable knowledge toward precision prevention. Exposome risk scores represent a promising research avenue.
    Keywords:  Bibliometrics; Digital environmental health; Digital public health; Disease; Exposome; Scientometrics
    DOI:  https://doi.org/10.1007/s11356-025-36197-7
  2. Clin Oncol (R Coll Radiol). 2025 Jan 30. pii: S0936-6555(25)00029-9. [Epub ahead of print]40 103774
    Global Research on the Treatment of Cancer Patients During the COVID-19 Pandemic: Visualisation and Bibliometric Analysis.
    T Chen, Y Wang, R Xie, L Dong, J Chen, L Yang.
       AIMS: The COVID-19 threatened global health, especially for cancer patients. We conducted a bibliometric analysis of the Science Citation Index literature published from 2019 to 2023 on the treatment of cancer patients during the COVID-19 pandemic, and explored the research trends and public interest in this topic.
    MATERIALS AND METHODS: A total of 4,941 articles in the Web of Science core collection on this topic were retrieved. The online analysis platforms of literature metrology were employed to do statistical analysis of the global annual volume of documents and citation frequency, perform cocitation analysis on authors, journals, and references, draw visual maps for countries or regions cooperation, institutional cooperation, author cooperation, and keyword cooccurrence, and then conduct keyword cluster analysis and keyword bursting.
    RESULTS: A total of 298 authors from 103 institutions and 74 countries or regions carried out research in the field, and the number of publications reached a peak in 2022. The United States, China, and Italy were the countries with the highest number of publications. The institutions that published the most papers are universities and research institutions. Keyword analysis showed that the research mainly focused on risk factors, outcomes, mortality, and therapy of cancer patients caused by COVID-19. Breast cancer was the cluster with the widest research scope. In addition to COVID-19, the burst keywords mainly included vaccination, delays, identification, immune response, malignancy, immunogenicity, and efficacy.
    CONCLUSION: The research on the treatment of cancer patients during the COVID-19 has shifted from laboratory research to clinical research, and the focus has gradually shifted from exploring the mechanism to improving the therapeutic effect. Developing vaccines and exploring treatment options that are more suitable for use in cancer patients, and investigating the relevance of the cytokine storms seem to concur with research priorities postpandemic. In the future, strengthening cooperation among countries or regions, institutions, and authors will be crucial for future pandemics.
    Keywords:  COVID-19; Cancer; CiteSpace; VOSviewer; therapy
    DOI:  https://doi.org/10.1016/j.clon.2025.103774
  3. Nurse Educ Pract. 2025 Mar 03. pii: S1471-5953(25)00078-2. [Epub ahead of print]84 104322
    Standardized patient simulation in nursing education: A bibliometric analysis and visualization from 2002 to 2024.
    Ebru Konal Korkmaz, Esin Ateş.
       AIM: This study employed a bibliometric analysis to examine the existing literature on the use of standardised patient simulation in nursing education.
    BACKGROUND: SP simulation offers students the opportunity to directly interact with a range of nursing interventions and practices. It demonstrates that SP simulation can be used as an active learning methodology in nursing education.
    DESIGN: Bibliometric and content analysis.
    METHODS: The data set was obtained from the Web of Science database. The sample comprised 310 publications that fulfilled the a priori defined inclusion criteria. The data were subjected to both descriptive content analysis and bibliometric analysis. A bibliometric analysis was conducted using VOSviewer, a software program designed for the mapping and visualisation of bibliometric data.
    RESULTS: A total of 198 publications were published in 2002-2024. The publications had 3042 citations. Nurse Education Today has the highest number of publications and citations. In terms of authors, Elcin was the author with the highest number of citations (n = 186). In accordance with the findings of the trend topic analysis, the keywords 'simulation', 'nursing education', 'standardised patient' and 'nursing students' emerged in the field.
    CONCLUSION: The number of studies examining the efficacy of using standard patient simulators in nursing education has seen a notable increase in recent years. The findings of this study may offer researchers and nursing faculties new insights into the value of incorporating standardised patient simulation into nursing education, as well as potential applications of such an approach.
    Keywords:  Bibliometric analysis; Nursing education; Nursing students; Standardized patient simulation
    DOI:  https://doi.org/10.1016/j.nepr.2025.104322
  4. Acta Inform Med. 2024 ;32(3-4): 160-176
    Bibliometric Indexes - Advantages and Limitations in Practical Application, for the Scientific Validity of Authors and Their Scientific Contents - Stanford Bibliometric List: Truths and Misconceptions.
    Izet Masic.
       Background: The scientific researchers have the role of interacting through published articles in scientific journals or presentations at scientific and professional conferences where they can affect the practices that can make achievements to society and country. or worldwide.
    Objective: The aim of this article was to describe bibliometric indexes and explained its importance for its evaluation and measuring quality assessment of published papers in scientific journals and advantages and disadvantages of current bibliometric portals for creating the list of universities and its academic staff by counts of deposited articles in databases and number of its citations.
    Methods: The author searched the most influential online databases and analyzed deposited papers by bibliometric indexes, and used a descriptive method to review important facts about bibliometrics experiences in scientific and academic practice. The author used facts deposited on the main international portals for analyzing number of citations of deposited scientific papers on Scopus and Google Scholar platform-h-Index and i10-Index and number of citations as basic data for created top list of most citated scientists in almost of all countries in the world.
    Results and Discussion: Bibliometric methods are used for quantitative analysis of written materials. Citation is influenced by: article quality, understanding of the article, language in which the article is written, loyalty to a group of researchers, article type, etc. Some indicators used in evaluating scientific work are Impact factor (IF); Citation of the article; Journal citations; Number and order of authors, etc. The index factor of influence depends on the quality of the journal, the language in which it was printed, the area it covers, and the journal distribution system. The portals and its platforms: Webometrics, "AD Scientific Index" and Stanford Bibliometric List are not fully relevant for measuring quality assessment of universities and its academic staff.
    Conclusion: Current academies and academicians can propose criteria how improve indexing scientific papers with the consultation of scientific bodies and experts at universities in one country, selected regions, or worldwide. These criteria should be necessary for quality assessment of the scientific curriculum of scientists and their published papers in scientific journals.
    Keywords:  AD Scientific Index; Google Scholar Index; Stanford Bibliometric List; Webometrics; h-Index
    DOI:  https://doi.org/10.5455/aim.2024.32.160-176
  5. J Craniovertebr Junction Spine. 2024 Oct-Dec;15(4):15(4): 467-474
    Unstable thoracolumbar injuries: A bibliometric analysis of the most influential papers.
    Eduardo Cattapan Piovesan, Werner Petry Silva, Alfredo Guiroy, Bruna Zanatta De Freitas, Vinícius Cercena Vargas, Charles Carazzo.
       Background: Bibliometric analyses are a proficient method for understanding the dynamics of publications. Unstable thoracolumbar injuries are a prevalent topic in neurosurgery and orthopedic research.
    Methodology: Web of Science was searched for the 100 most-cited articles on unstable thoracolumbar injuries. A number of citations, article title, first author's name, year and journal of publication and its impact factor (IF), specialty, affiliation, country of the first author, and type of the article were retrieved.
    Results: The articles were published in 32 different journals from 1977 to 2020. Spine (38 articles in the top 100 and 3694 citations) was the journal with the greatest number of articles and citations, and the highest number of primary research papers (31 articles, accounting for 2915 citations). The United States was the country with the most articles (45) and citations (4541). The University of California (5 articles, 6 primary research, and 781 citations) was the institution with the highest number of citations, articles, and primary research articles. Orthopedic was the specialty with the most significant number of publications and the most cited (77 articles and 7197 citations). The first author with the greatest number of publications and primary research articles was R. F. McLain (4 articles, being 3 primary research, and 646 citations), while the most cited was A. R. Vaccaro (3 articles and 695 citations). Eighty publications were primary and 20 were secondary research.
    Conclusions: The unstable thoracolumbar research field is prominent in North America and has been more frequently published in orthopedic journals, after 1995.
    Keywords:  Bibliometric analyses; neurosurgery; orthopedic; spinal cord; spine
    DOI:  https://doi.org/10.4103/jcvjs.jcvjs_43_24
  6. Front Med (Lausanne). 2025 ;12 1504428
    A bibliometric analysis of the advance of artificial intelligence in medicine.
    Mian Lin, Lingzhi Lin, Lingling Lin, Zhengqiu Lin, Xiaoxiao Yan.
       Introduction: The integration of artificial intelligence (AI) into medicine has ushered an era of unprecedented innovation, with substantial impacts on healthcare delivery and patient outcomes. Understanding the current development, primary research focuses, and key contributors in AI applications in medicine through bibliometric analysis is essential.
    Methods: For this research, we utilized the Web of Science Core Collection as our main database and performed a review of literature covering the period from January 2019 to December 2023. VOSviewer and R-bibliometrix were performed to conduct bibliometric analysis and network visualization, including the number of publications, countries, journals, citations, authors, and keywords.
    Results: A total of 1,811 publications on research for AI in medicine were released across 565 journals by 12,376 authors affiliated with 3,583 institutions from 97 countries. The United States became the foremost producer of scholarly works, significantly impacting the field. Harvard Medical School exhibited the highest publication count among all institutions. The Journal of Medical Internet Research achieved the highest H-index (19), publication count (76), and total citations (1,495). Four keyword clusters were identified, covering AI applications in digital health, COVID-19 and ChatGPT, precision medicine, and public health epidemiology. "Outcomes" and "Risk" demonstrated a notable upward trend, indicating the utilization of AI in engaging with clinicians and patients to discuss patients' health condition risks, foreshadowing future research focal points.
    Conclusion: Analyzing our bibliometric data allowed us to identify progress, focus areas, and emerging fields in AI for medicine, pointing to potential future research directions. Since 2019, there has been a steady rise in publications related to AI in medicine, indicating its rapid growth. In addition, we reviewed journals and significant publications to pinpoint prominent countries, institutions, and academics. Researchers will gain important insights into the current landscape, collaborative frameworks, and key research topics in the field from this study. The findings suggest directions for future research.
    Keywords:  VOSviewer; applications; artificial intelligence; bibliometrics; medicine
    DOI:  https://doi.org/10.3389/fmed.2025.1504428
  7. Dent Med Probl. 2025 Jan-Feb;62(1):62(1): 161-171
    Clear aligners: A network and bibliometric analysis of 50 pivotal articles.
    Vincenzo Grassia, Adriana Fiori, Federica Diodati, Babak Sayahpour, Abdolreza Jamilian, Niccolò Giuseppe Armogida, Fabrizia d'Apuzzo, Ludovica Nucci.
       BACKGROUND: A bibliometric analysis uses statistical and mathematical methods to analyze the published literature, extracting meaningful information that helps to identify trends, assess research impact, and visualize key data patterns through graphs and trendlines.
    OBJECTIVES: The aim of the study was to list the top 50 papers on clear aligners, evaluate them critically and apply a bibliometric analysis to investigate the achievements and prospects in this field of study.
    MATERIAL AND METHODS: A computerized database search (Scopus) was conducted on September 24, 2023, to find articles on clear aligners published in the scientific literature between 2013 and 2023. The top 50 cited manuscripts were chosen. Author-based characteristics were obtained from the Scopus database. The dataset from Clarivate™ InCites Benchmarking & Analytics™ and Journal Citation Reports (JCR) was used to determine parameters based on journals and articles. To improve the visual analysis, the keywords were collected systematically from the chosen articles.
    RESULTS: The database search produced a directory of the 50 most often cited articles out of 1,405 papers. Of the 50 most frequently cited works on clear aligners, 35 (70.0%) were original research studies and 15 (30.0%) were reviews. The keyword-network analysis indicated 'removable orthodontic appliance' as the most important and repetitive keyword.
    CONCLUSIONS: The results of the present bibliometric study indicated that clear aligner therapy (CAT)-related papers received increasing citations. The study determined the most influential articles by highlighting their authors and the journals in which the papers were published.
    Keywords:  bibliometric analysis; clear aligner; clear aligner treatment; network analysis; orthodontics
    DOI:  https://doi.org/10.17219/dmp/188319
  8. Front Med (Lausanne). 2025 ;12 1514686
    Knowledge mapping of autophagy in chronic obstructive pulmonary disease from 2004 to 2024: a bibliometric analysis.
    Yating Zhang, Anqi Li, Sumei Xu, Haoge Liu.
       Background: Chronic obstructive pulmonary disease (COPD) has become a major global healthcare issue due to its high prevalence and mortality rates. Increasing evidence suggests that autophagy plays a role in the development of COPD, yet there is a lack of bibliometric analyses on literature related to autophagy and COPD. Therefore, this study aims to summarize the current research status, research direction, and research hotspots in the literature related to COPD and autophagy.
    Methods: A search was conducted on the Web of Science Core Collection for literature related to COPD and autophagy from October 2004 to October 2024. Subsequently, bibliometric and visualization analyses were performed on the included publications using R software, CiteSpace, and VOSviewer.
    Results: A total of 481 published articles across 229 journals related to COPD and autophagy were included. During the study period, there was a trend of continuous growth in both the annual number of publications and citations in this field. The United States had the highest centrality, while China was the most productive country. Major research institutions included Maastricht University, Harvard University, and Jikei University. The American Journal of Physiology-Lung Cellular and Molecular Physiology, International Journal of Chronic Obstructive Pulmonary Disease, and Autophagy are the most influential journals in this field. The author with the most published papers is Araya J, while Choi AMK is the most influential author. Frequently appearing keywords include "oxidative stress," "obstructive pulmonary disease," "aging," "apoptosis," and "mitophagy."
    Conclusion: This bibliometric study helps researchers quickly understand the research overview of autophagy and COPD, thus providing new insights and directions for future research in this field.
    Keywords:  CiteSpace; VOSviewer; autophagy; bibliometric analysis; chronic obstructive pulmonary disease (COPD)
    DOI:  https://doi.org/10.3389/fmed.2025.1514686
  9. J Asthma. 2025 Mar 11. 1-16
    Global research trends and hotspots in mitochondria and asthma: A bibliometric and visualized analysis.
    Leming Huang, Chuyan Wu, Feng Jiang, Xinxin Bu.
       BACKGROUND: Asthma is a complex chronic respiratory disease marked by inflammation, bronchoconstriction, and hyperresponsiveness. Mitochondria, key regulators of energy production, ROS, and apoptosis, are increasingly recognized as crucial in asthma pathophysiology. However, a comprehensive analysis of global research trends in this area is lacking. This study aims to perform a bibliometric and visualized analysis of global research on mitochondria and asthma.
    METHODS: A bibliometric analysis was conducted using Web of Science Core Collection data from 2004 to June 2024. CiteSpace and VOSviewer software were used to examine co-authorship, co-citation, keyword co-occurrence, and thematic clusters.
    RESULTS: A total of 669 publications were identified. The number of studies grew significantly after 2015, with the United States, China, and the UK leading research. Co-citation and keyword analyses revealed mitochondrial dysfunction, oxidative stress, apoptosis, and airway inflammation as major themes. Emerging areas of interest include mitochondrial biogenesis, NLRP3 inflammasome, and innate immunity. Collaboration among institutions like Harvard University and the Council of Scientific & Industrial Research was significant, and journals such as European Respiratory Journal and Nature Medicine were highly influential.
    CONCLUSION: This study provides an overview of research on mitochondria and asthma, highlighting emerging trends such as mitochondrial biogenesis and immune pathways. Future research should focus on these areas and the role of environmental triggers in mitochondrial dysfunction, offering valuable insights for therapeutic strategies targeting mitochondria in asthma.
    Keywords:  Asthma; Bibliometric analysis; Co-citation network; Mitochondria; Mitochondrial dysfunction
    DOI:  https://doi.org/10.1080/02770903.2025.2478524
  10. J Arthroplasty. 2025 Feb 24. pii: S0883-5403(25)00163-9. [Epub ahead of print]
    Knee Society Members Are High Impact Researchers in the Field of Knee Arthroplasty: A Quantitative Analysis.
    Sayi P Boddu, Eeshaan Malladi, Roman P Austin, Mark J Spangehl, Joshua S Bingham, Henry D Clarke.
       BACKGROUND: Knee arthroplasty research continues to shape the field by improving both clinical practice and patient outcomes. The H-index is one metric that combines publication quantity and citation output in an attempt to quantify the impact of an author's research work. We aimed to assess the relative research impact of members of the Knee Society by comparing their H-indices and other research metrics to authors of the most cited knee arthroplasty publications.
    METHODS: The Clarivate Web of Science Database was utilized to perform a literature search for the most cited publications relating to knee arthroplasty. A list of the authors from these most cited publications was then collected. Author information and research metrics were extracted for both members of the Knee Society and authors of the most cited knee arthroplasty publications using the Scopus abstract and citation database. Descriptive and statistical analyses with Mann-Whitney U tests were used to compare various research metrics.
    RESULTS: The authors of the most cited knee arthroplasty studies have a higher mean H-index (57.3 versus 44.7, P = 0.017) and number of citations (22,343 versus 8,331, P < 0.001) than members of the Knee Society. Members of the Knee Society have a higher mean percentage of publications as senior authors (35 versus 23%, P < 0.001) and a higher mean number of publications specific to the last 10 years (118.3 versus 112.0, P < 0.001) than the most cited group. There was no significant difference between groups for the overall number of publications (223.6 for the Knee Society versus 255.8 for the most cited authors, P = 0.812).
    CONCLUSIONS: Based on research productivity and impact, membership selection in the Knee Society appears consistent with the goal of identifying high-impact individuals who are able to contribute to The Knee Society's mission.
    Keywords:  bibliometric analysis; h-index; knee society; total knee arthroplasty; unicompartmental knee arthroplasty
    DOI:  https://doi.org/10.1016/j.arth.2025.02.035
  11. Biomol Biomed. 2025 Mar 04.
    Trends in noninvasive ocular nanoparticle drug delivery: A bibliometric analysis (2004-2023).
    Dan Li, Qing Ye, Chao Li.
      This study presents a bibliometric analysis of research on noninvasive nanoparticle drug delivery systems for the transocular surface from 2004 to 2023. Relevant publications were retrieved from the Web of Science Core Collection. VOSviewer and CiteSpace were used to map contributions by countries/regions, authors, institutions, journals, keywords, keyword clusters, and timeline trends. A total of 695 articles were analyzed, showing a steady year-by-year increase in publications. China, the United States, and Spain were the leading contributors. Among authors, Alvarez-Lorenzo, Carmen was the most prolific, while Chanhan, Anuj's work received the most citations among the top 10 prolific researchers. The International Journal of Pharmaceutics published the highest number of articles in this field, whereas the Journal of Controlled Release was the most frequently cited among the top 10 most productive journals. The University of Santiago de Compostela and the University of Florida were among the most active institutions in this research area. Keyword analysis identified recent key themes, such as controlled release, cell interaction, dry eye, mechanisms, gene expression, and ocular drug delivery. The growing interest in transocular surface nanoparticle drugs is driven by their advantages, including increased solubility, improved stability, reduced administration frequency, sustained therapeutic concentrations, enhanced corneal penetration, and prolonged ocular surface residence time.
    DOI:  https://doi.org/10.17305/bb.2025.11772
  12. Front Rehabil Sci. 2025 ;6 1524303
    A bibliometric analysis of perioperative rehabilitation research between 2005 and 2024.
    Juan Li, Fen Su, Qing Zhang, Guiqi Song.
      Effective rehabilitation can improve the prognosis of surgical patients, thereby enhancing their medical experience. In recent years, relatively more research is been carried out in this field; therefore, it is necessary to use bibliometric analysis to understand the development status and main research hotspots of perioperative rehabilitation, so as to determine the role of rehabilitation in the perioperative period. All documents related to perioperative rehabilitation and published from 2005 to 2024 were retrieved from the Web of Science Core Collection (Woscc). Number of articles, countries/regions, institutions, journals, authors, and keywords were analysed using VOSviewer and CiteSpace. A total of 829 studies on perioperative rehabilitation were included in the bibliometric analysis. The number of articles has steadily and rapidly increased since 2016. Over time, the publication outputs increased annually. There are 532 keyword nodes in total, of which the five keywords that appear most frequently are "surgery" "rehabilitation" "Outcome" "management" and "complications". Research on the perioperative rehabilitation has developed rapidly. This study provides necessary information for researchers to understand the current status, collaborative networks, and main research hotspots in this field. In addition, our research findings provide a series of recommendations for future studies.
    Keywords:  CiteSpace; VOSviewer; VOSviewer bibliometric analysis; bibliometric analysis; perioperative; rehabilitation
    DOI:  https://doi.org/10.3389/fresc.2025.1524303
  13. Front Neurosci. 2025 ;19 1534735
    Bibliometric analysis of cognitive dysfunction after traumatic brain injury.
    Jihua Hu, Ruiting Zhu, Xin Zhang, Yuchen Zhang, Jixin Liu, Wenyang Wang, Chiyin Li, Tong Yang, Ming Zhang, Xuan Niu.
       Background: Cognitive dysfunction after traumatic brain injury (TBI) significantly reduces quality of life and imposes a heavy burden on society. A detailed examination of research trends of cognitive dysfunction following TBI has not yet been conducted. This study aimed to examine the bibliometric analysis of cognitive dysfunction after traumatic brain injury over the past 20 years.
    Methods: Literature on bibliometric analysis was retrieved from the Web of Science Core Collection (WoSCC) and Science Citation Index Expanded (SCI-E) from 2004 to 2023. The type of literature and the language were refined. A total of 1,902 articles were used for bibliometric analysis, including 1,543 (81.1%) original articles and 359 (18.9%) review articles. Data were retrieved on June 5, 2024.
    Results: The publication volume of articles was increasing year by year, with articles published in 537 journals. The Journal of Neurotrauma, with 130 articles, was the most productive and influential journal. The University of California System led in the number of articles published. There were 9,002 authors from 62 countries/regions. The USA and China were the top-ranked countries by article count. Pandharipande PP authored the highly cited article. Pick CG, as the author with the highest h-index. The top three of author keywords were traumatic brain injury, cognitive impairment, and mild traumatic brain injury. The topics of cognitive dysfunction after TBI were ferroptosis, cognitive decline, spinal cord injury, and prognosis.
    Conclusion: Our findings provide valuable insights into cognitive dysfunction following TBI and highlight emerging trends for future research.
    Keywords:  bibliometric analysis; cognition; cognitive dysfunction; head injury; traumatic brain injury
    DOI:  https://doi.org/10.3389/fnins.2025.1534735
  14. J Cosmet Dermatol. 2025 Mar;24(3): e70119
    A Bibliometric Analysis of the Top 100 Most-Cited Articles on Skin Photoaging.
    Yan Teng, Hui Tang, Yibin Fan, Jianhua You.
       BACKGROUND: In recent decades, our understanding of the pathogenesis and pathophysiology of skin photoaging has improved considerably, thereby enhancing preventive and management strategies. The bibliometric analysis demonstrates the chronological trends of publications, highlighting the most influential studies related to skin photoaging.
    OBJECTIVE: This study aims to identify and analyze the top 100 most-cited articles related to skin photoaging to offer bibliometric information.
    METHODS: The Web of Science database was searched to obtain publications on skin photoaging. Information from the top 100 most-cited articles was extracted and analyzed using Microsoft Excel 2019 and VOSviewer (version 1.6.18).
    RESULTS: The top 100 most-cited articles on skin photoaging received a total of 23 925 citations and an average of 239 citations per article. The top most-cited article received 1019 citations and 30.88 citations per article. The publication year ranged from 1995 to 2010, with a peak period of top publications between 2001 and 2005. The Journal of Investigative Dermatology and the Journal of the American Academy of Dermatology published the largest number of top-cited articles. The articles originated from nine different countries, with The United States as the highest contributor. Fisher GJ was the most productive first author from the University of Michigan in the United States and published a total of three articles. A total of 62 keywords were included and grouped into three clusters: 'matrix metalloproteinase', 'collagen' and 'radiation'. The article types include only reviews and original articles. Prevention and treatment-related studies were the most common research focus, followed by pathogenesis, pathophysiology, clinical features and screening methods.
    CONCLUSION: This bibliometric analysis on skin photoaging demonstrated a major upward trend in the prevention and treatment of skin photoaging, which provides a foundation for future research.
    Keywords:  Most‐cited articles; VOS viewer; bibliometric analysis; citation; skin photoaging; web of science
    DOI:  https://doi.org/10.1111/jocd.70119
  15. Healthcare (Basel). 2025 Feb 28. pii: 529. [Epub ahead of print]13(5):
    Trends in Physical Activity Research on Tobacco and/or Alcohol: A Bibliometric Analysis.
    Antonio Castillo-Paredes, Pablo Del Val Martín, Gerson Ferrari.
      Background/Objectives: Physical activity allows the enjoyment of personal health benefits in those who practice it, including the possibility of modifying behavioral risk factors such as tobacco and alcohol consumption. These risk factors are responsible for the development of non-communicable diseases, which are preventable and controllable. The scientific field on this object of study has grown in recent years. The main objective of this study was to perform a scientific mapping to explore the trend of annual publications, and to analyze and identify the thematic categories, the authors, countries and journals with the highest number of papers, the most referenced papers and authors, and the most used keywords in research related to physical activity and tobacco and/or alcohol consumption. Methods: Through a bibliometric analysis based on traditional bibliometric laws on the scientific documentation related to the subject and indexed in the Main Collection of the Web of Science. The DeSolla Price Law was used to analyze the trend of annual publications, using the coefficient of determination R2. Lotka's law was applied to identify prolific authors, Bradford's law to highlight the most frequent publication sources, the h-index to identify the most cited articles and Zipf's law to highlight the keywords most used in research. Results: A total of 538 documents were analyzed. The trend followed by annual publications is in an exponential growth phase. Adrian Taylor and Michael Ussher were identified as prolific authors. USA and Preventive Medicine were the country and journal with the highest number of publications. The most frequently used words were physical activity, smoking, exercise, alcohol, obesity, and smoking cessation. Conclusions: This bibliometric review identified an exponential growth from 1994 to date of research related to physical activity and tobacco and/or alcohol consumption. It allowed us to identify trends and guide the development of future research in these or new related areas.
    Keywords:  alcohol consumption; behavioral risk factors; physical activity; smoking; tobacco
    DOI:  https://doi.org/10.3390/healthcare13050529
  16. Front Pharmacol. 2025 ;16 1509259
    Knowledge structure and dynamic evolution of nanomedicine in liver cancer research: a scientometric analysis and visualization.
    Shaodong Li, Dapeng Cui, Bo Shao, Zhenhua Kang, Guoqiang Yan.
       Background: Nanomedicine has received much attention for its potential applications in the diagnosis and treatment of liver cancer. However, no bibliometric evaluation has been conducted to present an assessment of scientific progress in the field. The aim of this study is to comprehensively catalog the cooperation and influence of journals, countries, institutions, and authors in the field of nanomedicine in liver cancer from the perspective of bibliometrics, evaluate the clustering evolution of knowledge structure, and uncover hot topics and emerging themes.
    Methods: Articles and reviews related to nanomedicine and liver cancer were retrieved from the Web of Science Core Literature Library using Topic Search. #1 T= ("Hepatic Neoplasm*" OR "Liver Neoplasm" OR "Liver Cancer*" OR "Hepatocellular Cancer*" OR "Hepatic Cancer*"), #2 T= "nano*", the search strategy is set as #1 AND #2 limited to Science Citation Index Expanded database source, with no limitation of publication types and language/time. Bibliometric studies were conducted using CiteSpace and VOSviewer.
    Results: 2,648 articles and reviews were included from 2000 to 2024. The number of articles regarding nanomedicine in liver cancer showed an increasing trend. Analysis of the most productive journals shows that most are specialized in nanoscience and nanotechnology, pharmacology and pharmacy, and chemistry and multidisciplinary. These publications mainly come from 8,782 institutions in 297 countries led by China and the United States of America. Shao D published the most papers among the publications, while Jemal A had the most co-citations. The macroscopical sketch and micro-representation of the whole knowledge field are realized through co-citation analysis. Hepatocellular carcinoma, targeted delivery, sorafenib nanoparticles, and others are current and developing areas of study. The keywords "nanocrystals," "biodistribution," and "particles" also may be the focus of new trends and future research.
    Conclusion: In this study, bibliometrics and visual methods were used to review the research of nanomedicine in liver cancer comprehensively. The article will help scholars to gain a better understanding of the dynamic evolution of nanomedicine applications in liver cancer and point the directions for future research.
    Keywords:  VOSviewer; bibliometric analysis; citespace; liver cancer; nanomedicine; visualization
    DOI:  https://doi.org/10.3389/fphar.2025.1509259
  17. J Orthop Surg Res. 2025 Mar 14. 20(1): 275
    Global trends and hotspots of neuromodulation in spinal cord injury: a study based on bibliometric analysis.
    Shutao Gao, Yukun Hu, Shizhe Li, Wei Li, Weibin Sheng.
       OBJECTIVE: Spinal cord injury (SCI) is a debilitating condition that can result in permanent disability. Neuromodulation is a promising technology that has gained popularity as a treatment for SCI. This study aims to analyze the published literature to investigate the global trends and hotspots in research on neuromodulation in the context of SCI.
    METHODS: All relevant publications on the topic of neuromodulation in SCI from January 1, 2005, to September 17, 2024, were acquired from the Web of Science Core Collection database. Bibliometric analysis was performed to evaluate the publication distribution by country, institution, author, and journal, as well as keyword, using CiteSpace, VOSviewer, and Scimago Graphica software.
    RESULTS: Overall, 3,211 publications were eligible for inclusion in the analysis. The publication number in 2005 and 2024 were 77 and 222, respectively. A steady increasing trend in the publication number over the past two decades was observed. The Unites States published 1544 articles with 52,521 citations, ranking first regarding publication number and total citations. Case Western Reserve University was the most productive institution that published 181 papers. All of the highly productive institutions were located in the United States, Canada, and Australia. The University of California Los Angeles harvested 6626 total citations and 81.8 average citations, ranking first among the productive institutions. Gorgey AS published 60 articles and ranked first regarding total publication number. Edgerton VR harvested 4333 citations and ranked first among the authors for total citations. The analysis of high-yielding journals suggested that Journal of Spinal Cord Medicine was the most productive journal with 133 publications. Spinal Cord yielded 4200 citations and ranked first among the journals for total citations. The keyword analysis identified "functional electrical stimulation" and "spinal cord stimulation" as research hotspots.
    CONCLUSION: This study delineates the current knowledge landscape and research trends on the topic of neuromodulation in SCI. The findings highlight the growing interest in this field and underscore the significance of neuromodulation in SCI research.
    Keywords:  Bibliometric analysis; Neuromodulation; Spinal cord injury; Web of science
    DOI:  https://doi.org/10.1186/s13018-025-05674-7
  18. Comput Methods Biomech Biomed Engin. 2025 Mar 13. 1-14
    Knowledge mapping and research trends of cathelicidin peptide LL-37 from 1995 to 2024: a bibliometric study.
    Hongxin Shi, Peizhou Shu, Zhihao Wang, Chen Meng, Rao Yu, YongQing Xu, Chuan Li.
       BACKGROUND: To conduct a comprehensive bibliometric analysis of LL-37, summarize its development trends and patterns, and identify emerging research hotspots.
    METHODS: Bibliometric and Knowledge Graph Analysis of Literature Data Related to LL-37 in the WOSCC Database Using Citespace and Vosviewer.
    RESULTS: A total of 2,814 articles were analyzed, revealing a steady increase in recent publications. The USA and Sweden were the main contributors, with PLOS One publishing the most articles. Research on LL-37 in cancer and mast cells is emerging as a new focus.
    CONCLUSION: The research status and development trends of LL-37 were quantitatively analyzed, providing new directions for future studies.
    Keywords:  CiteSpace; LL-37; VOSviewer; bibliometric analysis; cathelicidin peptide
    DOI:  https://doi.org/10.1080/10255842.2025.2477218
  19. J Thorac Dis. 2025 Feb 28. 17(2): 724-743
    Global research trends on chronic thromboembolic pulmonary hypertension: a bibliometric analysis (January 2000-January 2024).
    Ye Lu, Yicheng Yang, Yinghui Fu, Changming Xiong, Fajiu Li, Xiaoming Zhou.
       Background: Chronic thromboembolic pulmonary hypertension (CTEPH), a progressive disease, can lead to decompensation of the right half of the heart and death. Studies on CTEPH have increased in number over the last two decades. This study aimed to perform a bibliometric analysis of the global scientific output on CTEPH in the last 24 years to identify research trends and hot topics.
    Methods: We searched the Web of Science Core Collection (WoSCC) Science Citation Index Expanded (Science Citation Index Expanded and Social Sciences Citation Index) for literature on CTEPH published from January 1, 2000 to January 31, 2024, and recorded their information. The Bibliometrix software package was used for bibliometric indicator analysis, and VOSviewer and CiteSpace were used to visualize trends and hotspots of CTEPH research.
    Results: Overall, 2,264 publications were included in the bibliometric analysis. The number of annual publications increased drastically from 14 in 2000 to 199 in 2023. The number of publications on CTEPH has increased over the last two decades, with 24.4% (n=553) of the publications published in top academic journals. The United States ranked first in publications and had the best CTEPH-investigating institutions; it also had the highest level of international cooperation. Distinctively, 7 of the top 10 institutions and 7 of the top 10 researchers in the field were from Europe with the most influential scientists. A relatively high percentage of the publications were published in top-rank academic journals, especially in respirology and cardiology journals. Pulmonary endarterectomy (PEA) was the main therapy during the first decade, while balloon pulmonary angioplasty (BPA) and pulmonary arterial hypertension (PAH)-targeted medicine have recently gained interest. Dual-energy computed tomography (DECT), right ventricular function, and the role of pulmonary endothelium in microvasculopathy have become the focus of CTEPH research.
    Conclusions: The number of publications on CTEPH has increased over the last two decades, and CTEPH has become a significant topic in both respirology and cardiology. Our results indicate that future research in this field will continue to focus on elucidating the pathophysiological mechanisms underlying this disorder, improving diagnostic accuracy, and developing novel imaging techniques. The integration of existing therapeutic modalities and the elucidation of right ventricular dysfunction are key areas of research.
    Keywords:  Chronic thromboembolic pulmonary hypertension (CTEPH); bibliographic; chronic thromboembolism; pulmonary embolism (PE); pulmonary hypertension (PH)
    DOI:  https://doi.org/10.21037/jtd-24-954
  20. Front Cardiovasc Med. 2025 ;12 1513942
    Pulsed field ablation for atrial fibrillation: a comprehensive bibliometric analysis of research trends and emerging Frontiers.
    Li Li, Bin Xie.
       Background: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia worldwide, posing significant health burdens. Pulsed field ablation (PFA) is an emerging non-thermal technique that is gaining traction due to the ability to selectively target myocardial cells and minimize damage to surrounding tissues. We conducted a comprehensive bibliometric analysis of PFA use in AF treatment to map research trends, collaborations, and future directions.
    Methods: We extracted data from the Web of Science Core Collection on September 6, 2024, using search terms related to PFA and AF. Publication trends, citation trajectories, collaborative networks, and keyword co-occurrences were analyzed utilizing tools such as Bibliometrix R, VOSviewer, and CiteSpace.
    Results: In total, 217 publications were retrieved. The number of publications increased rapidly from 2019 to 2024, with a notable surge occurring after 2022. Contributions from the United States, Germany, and China accounted for more than 60% of all publications. The institution with the largest output was The Icahn School of Medicine at Mount Sinai. The most productive journals were Europace and the Journal of Interventional Cardiac Electrophysiology. Prolific authors were identified, underscoring significant international collaborations. The most cited publications highlighted the efficacy and safety of PFA. Keywords with strong recent citation bursts included "tissue", "cardiomyopathy", and "closed chest ablation".
    Conclusion: PFA is becoming established as a viable alternative for AF ablation, showing promising safety and efficacy. This bibliometric analysis confirmed the growing scientific interest and collaborative efforts in this field, suggesting that robust future developments will occur.
    Keywords:  ablation techniques; atrial fibrillation; bibliometric analysis; cardiac electrophysiology; pulsed field ablation
    DOI:  https://doi.org/10.3389/fcvm.2025.1513942
  21. Front Oncol. 2025 ;15 1508173
    Bibliometric analysis: a study of the microenvironment in cervical cancer (2000-2024).
    Yun-Tao Zhang, Yan-Ni Wei, Chen-Chen Liu, Mai-Qing Yang.
       Objective: The incidence of cervical cancer has increased in recent years. The tumor microenvironment (TME) is the local biological environment involved in tumor occurrence and development. This study aimed to conduct a comprehensive analysis of the global research on the TME in cervical cancer (CC), providing a knowledge framework in this field from a holistic and systematic perspective based on a bibliometric analysis.
    Methods: Studies focusing on the TME in cervical cancer were searched using the Web of Science Core Collection database. The annual output, cooperation, hotspots, research status, and development trends in this field were analyzed using bibliometric softwares (VOSviewer and CiteSpace).
    Results: A total of 1,057 articles published between 2000 and 2024 were selected. The number of publications and citations has recently increased. Cooperation network analysis indicated that China holds the foremost position in research on the TME in cervical cancer with the highest volume of publications, thus exerting the greatest influence. Fudan University had the highest output. Frontiers in Oncology showed the highest degree of productivity in this field. Rofstad, Einar K. made the most article contributions and was the most co-cited author. Four clusters were obtained after a cluster analysis of the keywords: TME, cervical cancer, immunotherapy, and prognosis. Immunotherapy, human papillomavirus, and biomarkers were relatively recent keywords that attracted increasing attention from researchers.
    Discussion: This bibliometric analysis provides a data-based and objective introduction to the TME of cervical cancer, and offers readers a valuable reference for future research.
    Conclusions: Comprehensive research in this field was mainly distributed in the TME of cervical cancer through the analysis of keywords and documents. Sufficient evidence supports mechanism research and application exploration. Further research should explore new topics related to the TME of cervical cancer.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; cervical cancer; tumor microenvironment
    DOI:  https://doi.org/10.3389/fonc.2025.1508173
  22. Front Aging Neurosci. 2025 ;17 1544702
    A bibliometric analysis of research hotspots and trends in transcranial magnetic stimulation and Alzheimer's disease.
    Dingwen Xu, Yang Feng, Zhihua Lu, Ruijia Ma, Weicai Zhang, Zhen Mou, Lingling Zhang, Xiufeng Tang, Zhenxiong Zhao, Zhencang Zheng.
       Background: Research regarding Transcranial Magnetic Stimulation (TMS) and Alzheimer's disease (AD) has been increasing; however, no bibliometric analysis has yet been conducted in this domain. This study employs bibliometric methods to identify research trends and hotspots concerning AD and TMS.
    Methods: We conducted a search in the Web of Science Core Database for articles related to AD and TMS from January 1, 2014, to October 22, 2024. After stringent selection, we performed bibliometric analysis using Excel, VOSviewer, CiteSpace and CoreMine.
    Results: The number of articles pertaining to AD and TMS has increased annually, with a notable surge post-2020. The three leading countries in publication volume are China, the United States, and Italy. The top institutions contributing to this field include Harvard Medical School, the University of Toronto, and the University of Brescia. The author with the highest publication output is Giacomo Koch. The journal with the most publications is the Journal of Alzheimer's disease. The 10 most frequently occurring keywords are Alzheimer's disease, Transcranial Magnetic Stimulation, mild cognitive impairment, dementia, memory, double-blind, repetitive transcranial magnetic stimulation, noninvasive brain stimulation, cognitive impairment, and plasticity. Text mining has revealed that the anatomical structure "brain" and the gene "Amyloid Precursor Protein (APP)" are significantly related to both AD and TMS, suggesting that TMS may offer a therapeutic avenue for AD by modulating the activity of APP.
    Conclusion: Our article employs bibliometric methods to unveil trends in research related to AD and TMS, including collaborations among countries, regions, and authors, as well as key research hotspots. We provide objective data that serves as a reference for scientific research and clinical work concerning AD and TMS.
    Keywords:  Alzheimer’s disease; bibliometric analysis; dementia; double-blind; memory; mild cognitive impairment; publication; transcranial magnetic stimulation
    DOI:  https://doi.org/10.3389/fnagi.2025.1544702
  23. Clin Imaging. 2025 Mar 11. pii: S0899-7071(25)00042-7. [Epub ahead of print]121 110442
    The 100 most-cited radiomics articles in cancer research: A bibliometric analysis.
    Wenhao Zhang, Dongmei Zhuang, Wenzhuo Wei, Yuchen Yang, Lijun Ma, He Du, Anran Jin, Jingyi He, Xiaoming Li.
      Radiomics, an advanced medical imaging analysis technique introduced by Professor Lambin in 2012, has quickly become a key area of medical research. To explore emerging trends in cancer-related radiomics, we conducted a bibliometric analysis of the 100 most-cited articles (T100) in this field. Data were collected from the Web of Science Core Collection on October 7, 2023, and the articles were ranked by citation count. We extracted data such as authors, journals, citation counts, and publication years and analyzed it using Microsoft Excel 2019 and R 4.4.2. CiteSpace was used to create co-occurrence and citation burst maps to show the relationships between authors, countries, institutions, and keywords. The analysis revealed that the T100 came from 81 countries, with the U.S. contributing the most (56 articles). Harvard University was the leading institution, and the journal Radiology had the highest citation count. Aerts Hugo JWL was the most influential author. The study highlights that "lung cancer" and "artificial intelligence" are emerging as major research hotspots, shaping the future of cancer radiomics.
    Keywords:  Bibliometric analysis; Cancer; CiteSpace; Radiology; Radiomics
    DOI:  https://doi.org/10.1016/j.clinimag.2025.110442
  24. J Multidiscip Healthc. 2025 ;18 1297-1317
    A Bibliometric Analysis of the Application of Brain-Computer Interface in Rehabilitation Medicine Over the Past 20 Years.
    Jinghui Huang, Lele Huang, Ying Li, Fanfu Fang.
       Objective: This study aims to conduct a bibliometric analysis of the application of brain- computer interface (BCI) in rehabilitation medicine, assessing the current state, developmental trends, and future potential of this field. By systematically analyzing relevant literature, we seek to identify key research themes and enhance understanding of BCI technology in rehabilitation.
    Methods: We utilized bibliometric analysis tools such as VOSviewer and CiteSpace to screen and analyze 426 relevant articles from the Web of Science Core Collection (WoSCC) database. We quantitatively evaluated citation patterns, publication trends, and the collaboration networks of research institutions and authors to uncover research hotspots and frontier dynamics in the field.
    Results: The findings indicate a continuous increase in research publications since 2003, with a notable peak occurring between 2019 and 2021. The analysis revealed that motor imagery, motor recovery, and signal processing are the predominant research themes. Furthermore, the United States and China are leading in the publication volume related to BCI and rehabilitation medicine. Key research institutions include the University of Tübingen and the New York State Department of Health, with significant contributions from scholars like Niels Birbaumer.
    Conclusion: Although the current research on BCI in rehabilitation medicine shows significant potential and efficacy, further exploration of certain research directions is needed, along with the promotion of interdisciplinary collaboration to comprehensively address complex real-world issues such as motor function impairment. Future research should focus on optimizing training models, enhancing technical feasibility, and exploring home rehabilitation applications to facilitate the broader adoption of BCI technology in rehabilitation medicine.
    Keywords:  BCI; brain-computer interface; motor imagery; motor recovery; rehabilitation; signal processing
    DOI:  https://doi.org/10.2147/JMDH.S509747
  25. J Multidiscip Healthc. 2025 ;18 1281-1295
    Mapping the Knowledge Landscape of and Emerging Future Trends in Stem Cell Therapy for Osteoarthritis: A Bibliometric Analysis of the Literature From 1998 to 2024.
    Zhishou Meng, Dongqin He, Honggang Wang, Lijuan Ma, Le Guan, Yongning Ai, Jianxin Yang, Ruxing Liu.
       Objective: The purpose of this study was to conduct a bibliometric analysis of the literature on stem cell therapy for osteoarthritis (OA) to visualize recent developments, identify hot spots, and determine trends in the field.
    Background: OA is a chronic disease that affects the joints and their surrounding tissues, leading to progressive damage to the articular cartilage and ultimately to the subchondral bone and the surrounding synovial structures. OA is a disabling disease with an increasing incidence and prevalence in the general population. Modulation of immunity and inflammation and improvement of cell survival and differentiation through multidirectional differentiation of stem cells is a potential strategy for the treatment of OA.
    Methods: We searched for publications on "stem cell therapy for osteoarthritis" in the Web of Science (WOS) core collection database from 1998-2024 and summarized the results, including year of publication, country, institution, author, and collaborative network generated using VOSviewer and Citespace. In addition, research trends were identified. Finally, we summarized the hot topics and identified future research trends.
    Results: This study ultimately included 2341 valid papers, with a trend toward a gradual increase in the number of publications over time. The country, institution, author, and journal with the highest number of publications and citations were China, the University of California system, Sekiya I, and Osteoarthritis and Cartilage, respectively. High-frequency keyword clusters included cell therapy, stem cells, tissue engineering, and extracellular vesicles.
    Conclusion: Through visualization and analysis, we elucidated the trends and research hotspots in the field over the past five years. The analysis revealed that stem cell transplantation and exosome therapy for OA may be the focus of future research. This study lays the foundation for future research and clinical work on stem cell therapy in this field.
    Keywords:  VOSviewer; bibliometric analysis; citespace; exosome; extracellular vesicles; osteoarthritis; stem cell; tissue engineering
    DOI:  https://doi.org/10.2147/JMDH.S508807
  26. Discov Oncol. 2025 Mar 11. 16(1): 292
    Research trends and highlights in PD-1/PD-L1 inhibitor immunotherapy in lung cancer: a bibliometric analysis.
    Zheng Gu, Erle Deng, Jing Ai, Fei Wu, Qiang Su, Junxian Yu.
       BACKGROUND: Lung cancer is one of the most common malignant tumors worldwide. This article aims to review the current research status and trends in PD-1/PD-L1 inhibitor immunotherapy.
    METHOD: On the basis of the Web of Science Core Collection database, literature on PD-1/PD-L1 inhibitor immunotherapy in lung cancer patients was searched and analyzed for all years up to August 5, 2023. Bibliometric techniques were employed, including CiteSpace (6.1.R6), VOSviewer, and the Bibliometrix package in R, to examine publication counts, countries, institutions, authors, journals, cited literature, keywords, and research trends.
    RESULTS: A total of 1,252 documents were included following the screening process. The analysis revealed that China had the highest number of publications (512), whereas the institution with the most publications was the UDICE French Association of Research Universities Union (193). The journal with the most articles was the Journal for Immunotherapy of Cancer (48), and the most prolific author was Zhou Caixun from Tongji University in China (20). Co-citation analysis revealed that Borghaei H's 2015 article in the New England Journal of Medicine had the highest citation frequency. The clustering results indicated that the most frequently referenced keywords included predictors, treatment monitoring, and hyperprogressive diseases. There is a growing trend toward combination therapies, such as dual immune checkpoint inhibitors, and research into molecular mechanisms within the tumor microenvironment, aimed at enhancing the efficacy of immunotherapy and reducing adverse effects.
    CONCLUSION: Bibliometric analysis indicates that PD-1/PD-L1 inhibitors are pivotal in lung cancer immunotherapy. Research in this domain focuses on identifying biomarkers within the tumor microenvironment, addressing immune evasion and resistance to maximize efficacy, and mitigating adverse effects.
    Keywords:  Bibliometrics; Immunotherapy; Lung cancer; PD-1/PD-L1
    DOI:  https://doi.org/10.1007/s12672-025-02052-x
  27. Front Cell Infect Microbiol. 2025 ;15 1507667
    Global research trends in the intestinal microflora and depression: bibliometrics and visual analysis.
    Qian Xu, Qingwei Xiang, Zihu Tan, Qiong Yang.
       Background: In recent years, the relationship between gut microbiota and human health has garnered significant attention. Notably, the potential connection between gut microbiota and mental health issues, such as depression and anxiety, has emerged as a new focal point for research. While some studies suggest a possible link between these factors, the field remains in its early stages of development, and there are notable methodological and sample size limitations.
    Purpose: This study aims to systematically summarize the knowledge systems, research hotspots, and development trends related to intestinal microflora within the context of depression research.
    Methods: This study conducted a search for publications related to intestinal microflora and depression in the Web of Science Core Collection (WOSCC) prior to August 6, 2024. The selected literature was subsequently analyzed using VOSviewer (v.1.6.20), SCImago Graphica (v.1.0.39), and CiteSpace (v.6.3.1).
    Results: The study encompassed a total of 1,046 publications, demonstrating a consistent increase in annual publication volume. The primary research countries identified are China and the United States, with notable contributions from institutions such as the University of California and University College Cork, among others. Keywords analysis highlighted high-frequency terms including "gut microbiota," "depression," and "anxiety," and revealed 10 keyword clusters along with 20 strongest citation bursts keywords. The focus of research has shifted from compositional analysis of gut microbiota to its role in the pathogenesis of depression.
    Conclusions: Research on gut microbiota and depression is growing, but there is still a need for greater collaboration between authors and institutions across regions, more ongoing interaction and communication to further explore the mechanisms of action of gut microbiota, to develop microbiota-based interventions, and to facilitate translation of research findings into clinical practice.
    Keywords:  bibliometric analysis; depression; intestinal flora; research hotspot; research trend
    DOI:  https://doi.org/10.3389/fcimb.2025.1507667
  28. Front Med (Lausanne). 2025 ;12 1518173
    Research status and hotspots of hypothermia and human diseases: a bibliometric analysis.
    Wei-Xuan Li, Na-Na Han, Qian-Yu Ji, Xue-Tong Dong, Chao-Long Lu, Song-Jun Wang.
       Background: Hypothermia has been strongly associated with human diseases; it affects life safety. Therapeutic hypothermia generates good results for certain diseases, without serious complications. In clinical practice, research on the treatment of hypothermia and severe hypothermia-induced diseases have achieved fruitful results. However, no bibliometric analysis has been conducted. In this study, we explored the research status and hotspots of hypothermia and human diseases by conducting a bibliometric analysis.
    Methods: Articles on hypothermia and human diseases were collected from the Web of Science Core Collection. From 1 January 2005 to 31 August 2024, A total of 1,553 articles were retrieved. After excluding irrelevant articles, 706 articles were analyzed.
    Results: The United States and China published the maximum number of research articles on hypothermia and human diseases. Among institutes, Johns Hopkins University and Harvard University published the maximum number of research articles. Scholars, including Ishikawa Takaki, Maeda Hitoshi, and Michiue Tomomi, constituted a highly productive group of authors. The journal, Therapeutic Hypothermia and Temperature Management published the highest number of articles, and Nature Reviews Drug Discovery had the highest impact factor. Cluster analysis of all keywords primarily focused on the following research directions: (i) hypothermia-related injury, (ii) hypothermia treatment, and (iii) the mechanism underlying hypothermia.
    Conclusion: This bibliometric study comprehensively summarizes the impact of hypothermia on human diseases and the research overview of the use of moderate hypothermia for treatment. This paper clarifies the research status, frontiers and hotspots, and also puts forward new insights for hypothermia research: strengthen research cooperation to improve the depth of research, increase support for areas with insufficient medical conditions; in the future, single-cell multiomics technology will be used to explore cell types sensitive to different low temperatures and corresponding molecular mechanisms; non-coding RNA regulation will be used to achieve precision treatment of hypothermia diseases; Organoids will be an important object of hypothermia research. These research insights can provide reference for researchers.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; human disease; hypothermia; injury
    DOI:  https://doi.org/10.3389/fmed.2025.1518173
  29. Chin Clin Oncol. 2025 Feb;14(1): 6
    Bibliometrics of gastric cancer prediction models.
    Fei Gao, Xiaohan Wang, Xifeng Fu, Jingchao Sun.
      This paper analyzes the manuscripts in the field of gastric cancer (GC) prediction, guiding clinical work and prevention of GC. Using a search strategy, we retrieved research articles related to GC prognosis from the Web of Science (WOS) core database: topic search (TS) = ((gastric cancer OR stomach cancer) AND (survival rate OR survival analysis OR prognosis) AND (predict model)). We set the language to English, the document type to article and review, and completed the search on July 1, 2023. We obtained 1,598 relevant articles, and two researchers screened the search results again, excluding irrelevant, misclassified, and retracted articles. Any controversial articles were reviewed by a third researcher to make the final decision on the required literature. We finally selected 1,056 articles, excluding 542 articles, and extracted the required data from the WOS database for analysis. The extracted database included: title, publication year, author, country/region, institution, citation count, journal, keyword, and reference. We used R (4.3.0) to load the R package (bibliometrix) for bibliometric analysis. The 1,056 articles came from 273 sources (journals, books, etc.), and 3,661 authors conducted relevant research on GC prognosis models. Frontiers in Oncology published the most articles (N=72), and Gastric Cancer Journal had the most citations (N=1,130). The publication time span ranged from 1991 to 2023, with an average annual growth rate of 13.31%. The number of publications increased from 2017, with a sharp increase from 2020 to 2023. The five countries with the most publications were China (n=826), Japan (n=62), Korea (n=47), USA (n=42), Italy (n=19). China had the most citations (N=9,595), and USA had the highest average citation per article (44.9 times). The most common topic was GC survival (n=236), followed by expression (n=209). Multiple GC prediction models in this study describe the science of predicting GC incidence and prognosis. This work provides the most influential references related to GC prediction and serves as a guide for citable papers.
    Keywords:  Bibliometric analysis; gastric cancer (GC); prognosis models; survival analysis
    DOI:  https://doi.org/10.21037/cco-24-63
  30. Medicine (Baltimore). 2025 Mar 07. 104(10): e41772
    Nutritional therapy in palliative care units: A bibliometric analysis.
    Özlem Öner, Pinar Ayvat, Ali Necati Gökmen.
      This bibliometric review aimed to provide a general picture and systematic mapping of research trends in palliative care (PC) and nutrition internationally. The Web of Science (WoS) database was searched on May 7, 2024, for original articles focusing on PC and nutrition between 1970 and 2023. Relevant publications were searched using the Thompson Reuters Science Citation Index (SCI) search engine with the keywords "palliative care," "palliative care unit," "nutrition," and "palliative care and nutrition." A total of 918 articles were found in 391 sources with the participation of 4772 authors. An average of 18.32 citations per article was identified. When analyzed by country, the United States of America (USA) had the highest number of publications (n = 210), followed by Germany (n = 71) and France (n = 69). In the list of the most frequently repeated keywords in the field of PC and nutrition, the most commonly used words were "palliative care" and "end." Other common terms included "nutrition," "quality of life," and "hydration." Additional frequently used words were "cancer," "symptoms," and "management.." This study is the first step toward analyzing and mapping research related to PC and nutrition. It shows that the number of publications related to PC and nutrition has steadily increased between 1991 and 2023. United State of America and European countries are the top publishers and receive the most citations. Hot topics in the field include "end," "nutrition," "quality of life," "hydration," "cancer," "symptoms," and "management," highlighting the complexity of the subject.
    DOI:  https://doi.org/10.1097/MD.0000000000041772
  31. Indian J Otolaryngol Head Neck Surg. 2025 Jan;77(1): 232-241
    Bibliometrics and National Institutes of Health Funding: Associated Factors in Academic Rhinology.
    Lucy Revercomb, Aman M Patel, Om B Tripathi, David W Wassef, Paul T Cowan, Cynthia Schwartz, Andrey Filimonov.
      Our study aims to evaluate demographics and research productivity in academic rhinology and to establish the relationship between bibliometrics such as the Hirsch index (h-index) and the more recently developed relative citation ratio (RCR) and National Institutes of Health (NIH) funding. Retrospective cohort study. The demographics of academic rhinologists were collected from institutional faculty profiles (N = 207). Funding data were obtained from the NIH Research Portfolio Online Reporting Tools Expenditures and Reports Database. The h-index was calculated using Scopus. The mean (m-RCR) and weighted RCR (w-RCR) were calculated using the NIH iCite tool. The majority of academic rhinologists were men (72.9%). Only 8.7% of rhinologists (N = 18) received NIH funding. Rhinologists receiving NIH funding had greater h-index (31 vs. 11), m-RCR (2.6 vs. 1.6), and w-RCR (339.9 vs. 44.7) (P < 0.001). Men had greater h-index (14 vs. 10, P < 0.001) and w-RCR (56.8 vs. 36.9, P = 0.025) but not m-RCR (1.7 vs. 1.6, P = 0.799) than women. Stratifying by academic professorship rank and across all career durations, h-index, m-RCR, and w-RCR were not significantly different between men and women. Among academic rhinologists the h-index, m-RCR, and w-RCR were all associated with receiving NIH funding. Similar h-index, m-RCR, and w-RCR between men and women across all academic professorship ranks and career durations suggests production of similar quality and quantity of research. The m-RCR and w-RCR help to address some of the limitations of the h-index and are useful for assessing research productivity.
    Keywords:  Bibliometric; NIH funding; Relative citation ratio; Research productivity; Rhinology
    DOI:  https://doi.org/10.1007/s12070-024-05156-y
  32. Curr Med Chem. 2025 Mar 10.
    Six Decades of Scientific Output: A Bibliometric Analysis of Research Contributions from the National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez".
    Carmen Rubio, Rudy Luna, David Vázquez, Veronica Perez de la Cruz, Benjamin Pineda, Antonio Arauz.
       INTRODUCTION: The Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez (INNNMVS), established nearly six decades ago, was initially designed as a specialized hospital for neurological care. However, over time, it has evolved into a multifaceted health institute, encompassing three fundamental pillars: clinical care, scientific research, and academic education in neurology.
    AIMS AND OBJECTIVES: The purpose of this study is to strengthen and expand knowledge in the field of neurology. Within the context of INNNMVS, sixtieth anniversary, our goal is to examine bibliometric data from this tertiary healthcare institution, providing evidence of productivity and progress in the research field within the institute and demonstrating scientific trends and their correlation with prevalent neurological diseases in Mexico, to enhance international recognition of this institution.
    METHOD: The research data from the Scopus database were obtained from the INNNMVS starting from its establishment in 1964 until 2023. We systematically classified each article and conducted a comprehensive analysis of various variables, including topic, type, citations, journal of publication, year of publication, language, collaboration, and other relevant factors. The INNNMVS has published a total of 3,915 articles between the years 1964 and 2023, with publication commencing in 1968. Since 2005, the INNNMVS has consistently published over 100 articles annually.
    RESULTS: The predominant causes of illness and death in Mexico, which have received significant research attention at the INNNMVS, include strokes, tumors, psychiatric disorders, infectious diseases, epilepsy, Parkinson's disease, and autoimmune diseases. Simultaneously, these are the most frequently cited data. The scientific output of the INNNMVS has experienced substantial growth over the past few decades.
    CONCLUSION: The most successful articles possess attributes that are absent in the majority of articles published by the INNNMVS. We extend an invitation to this institution to engage in collaborative partnerships with international affiliations and to contribute scholarly articles to esteemed international journals.
    Keywords:  Bibliometric analysis; biomedical research; neuroscience; public health; scientific production.
    DOI:  https://doi.org/10.2174/0109298673343760250217111056
  33. Nurse Educ Today. 2025 Mar 01. pii: S0260-6917(25)00088-7. [Epub ahead of print]149 106653
    Bibliometric analysis of high-fidelity simulation training in nursing.
    Glauber Cavalcante Oliveira, Aélya Drisana Dias Gomes de Araújo, Francisco Reginaldo da Silva Júnior, Layara Fernandes Barros, Francisco Wagner Dos Santos Sousa, Francisca Tereza de Galiza.
       BACKGROUND: While advances have been made in the field of high-fidelity realistic simulation in nursing, bibliometric studies in this field are limited.
    OBJECTIVES: The objectives were: (1) to examine the number of articles published in the field of nursing on high-fidelity realistic simulation with a time frame from 2009 to 2023; (2) to identify the scientific journals that publish the most on high-fidelity simulation in nursing; (3) to analyze the authorship of scientific publications on high-fidelity simulation in nursing.
    DESIGN: This is a bibliometric study of high-fidelity simulation in nursing.
    METHODS: The search was carried out in the Web of Science database, using the controlled vocabulary available in the MESH Terms, "High-Fidelity Simulation Training". To compose the final sample, the following inclusion criteria were taken into account: original article, available in its entirety, involving the training of nursing professionals. Exclusion criteria applied were: review studies, not focusing solely on the training of nursing professionals.
    RESULTS: A total of 191 manuscripts were obtained. For the selection stage, the EndNote software was used to exclude duplicate studies; sequentially, the studies were exported to the Rayyan software for selection by reading the title and abstract, for subsequent analysis of the studies by the inclusion and exclusion criteria, a total of 72 studies were obtained for analysis. The number of studies on training nursing staff has shown an upward curve over the years. The journals that published the most on the subject over the years were Nurse Education Today (n = 10), Clinical Simulation in Nursing (n = 7) and Healthcare (n = 5). The authors who published the most on the subject were: Arrogante, O (n = 11), Jimenez-Rodriguez, D (n = 6), Carrion-Garcia, L. (n = 3).
    CONCLUSION: The concentration of scientific productions on high-fidelity realistic simulation, by author affiliation, has been in Europe and the United States of America, with an increase in publications over the last decade.
    Keywords:  Bibliometric analysis; Education, nursing; Education, nursing, continuing; Education, nursing, graduate; Evidence synthesis; High fidelity simulation training
    DOI:  https://doi.org/10.1016/j.nedt.2025.106653
  34. Health Sci Rep. 2025 Mar;8(3): e70469
    Mapping Global Scientific Production on Human Immunodeficiency Virus and Monkeypox: A Scientometric Study.
    Frank Mayta-Tovalino, Carlos Quispe-Vicuña, Cesar Mauricio-Vilchez, Diego Galarza-Valencia, Fran Espinoza-Carhuancho.
       Background and Aim: HIV attacks the immune system, leading to AIDS if untreated. Mpox, a zoonotic disease like smallpox, is less severe but poses higher risks for immuno-compromised individuals, especially those with HIV. Effective prevention and treatment are crucial. This study aims to assess the global academic output on Monkeypox (MPVX) and HIV during 2018-2023.
    Methods: This descriptive, bibliometric study reviewed the published literature on "monkeypox" and "HIV" during the period 2018-2023. The search was conducted on February 11, 2024, using a systematic formula. We identified 366 potential articles, including various types of papers. When exporting metadata to SciVal for the period 2018-2023, 8 metadata could not be exported. The remaining data were analyzed using SciVal and Bibliometrix in R Studio, providing an overview of research productivity, collaborations, and citation impact.
    Results: During the period 2018-2023, 366 papers on "monkeypox" and "HIV" were published in 183 different sources, with an annual growth rate of 208.18%. These papers had an average of 14.78 citations per paper. An additional 2522 keywords and 638 author keywords were identified. The "Journal of Medical Virology" led the academic output with 20 papers, followed by "The Lancet Infectious Diseases" with 11 papers. The "Institut national de la santé et de la recherche médicale" in France led the academic output. These data are specific to papers dealing with "monkeypox" and "HIV."
    Conclusion: Research on Monkeypox and HIV has grown significantly during the period studied, with remarkable international collaboration. These findings underscore the importance and global impact of Monkeypox and HIV research.
    Keywords:  HIV; Mpox; bibliometrics; global public health
    DOI:  https://doi.org/10.1002/hsr2.70469
  35. Eur J Pharmacol. 2025 Mar 05. pii: S0014-2999(25)00233-X. [Epub ahead of print]997 177479
    Mapping the evolution of anti-diabetic polysaccharides research: Trends, collaborations, and emerging frontiers.
    Shengqi He, Taotao Xue, Ruoyu Geng, Qianqian Wang, Baojuan Wang, Limei Wen, Mingjie Li, Junping Hu, Jianhua Yang.
      Diabetes Mellitus, characterized by insufficient insulin secretion, pancreatic beta cell damage, or insulin resistance, is the third most prevalent chronic metabolic disease worldwide. Polysaccharides, biocompatible natural macromolecules, have garnered significant attention for their potential in modulating diabetes through various mechanisms. Despite extensive studies, a comprehensive and impartial evaluation of anti-diabetic polysaccharides (ATDPs) research is still lacking. This study employs bibliometric and knowledge mapping techniques to analyze research trends and developments concerning ATDPs. A total of 3435 publications from 2001 to 2024 were examined, revealing a marked increase in publication volume and citation frequency, particularly since 2016. Network analysis indicates China as the leading contributor, with the highest number of publications and prominent institutions. The International Journal of Biological Macromolecules is identified as the most prolific journal in this field. Shaoping Nie stands out as a leading researcher with the highest citation frequency and h-index. Current research trends focus on the role of polysaccharides in regulating oxidative stress and inflammation, modulation of gut microbiota, and their structural characterization. Emerging studies investigate how these polysaccharides impact gut microbiota composition, enhance intestinal barrier functions, and modulate immune responses, representing cutting-edge areas in diabetes research. This research pioneers the use of bibliometric analysis to map ATDPs research trajectories, offering valuable insights into prevailing trends, emerging topics, and opportunities for future research and collaboration.
    Keywords:  Anti-diabetic polysaccharides; Bibliometric analysis; Diabetes mellitus; Gut microbiota modulation; Oxidative and inflammatory regulation
    DOI:  https://doi.org/10.1016/j.ejphar.2025.177479
  36. Front Neurol. 2025 ;16 1502657
    Bibliometric and visual analysis in the field of electroacupuncture's analgesia and regulation on negative emotion from 2014 to 2024.
    Xubo Huang, Jiajie Gao, Yuxin Ding, Jiali Wang, Junfan Fang, Jianqiao Fang, Junying Du.
       Introduction: This bibliometric study systematically analyzes the research landscape of electroacupuncture (EA), focusing on its applications in pain relief and emotional regulation from 2014 to 2024. EA, a contemporary adaptation of traditional acupuncture, has gained significant attention for its potential therapeutic benefits in managing chronic pain and mood disorders.
    Methods: Using the Web of Science Core Collection as the primary data source, we identified 537 articles related to EA's therapeutic effects. The analysis was conducted using bibliometric tools such as VOSviewer and CiteSpace to visualize publication trends, research hotspots, and collaborative networks.
    Results: The study highlights a significant upward trend in research output, with a marked increase in publications from 2019 onwards. China emerged as the leading contributor, accounting for over 60% of the total research output, followed by the United States and South Korea. Key institutions, such as Zhejiang Chinese Medical University and Shanghai University of Traditional Chinese Medicine, have made substantial contributions, emphasizing the importance of traditional Chinese medicine in this research area. Major research themes include the modulation of neurotransmitter systems, the role of endogenous opioids, and the impact of EA on chronic pain and mood disorders. Collaborative networks between countries and institutions are mapped, revealing the centrality of Chinese and American research partnerships.
    Discussion: This comprehensive analysis outlines the current state of EA research and identifies gaps and opportunities for future studies, particularly in understanding the mechanistic pathways of EA and its integration into mainstream medical practices. The findings provide a roadmap for enhancing the therapeutic applications of EA and underscore its potential in managing complex conditions involving both physical and emotional components.
    Keywords:  analgesia; bibliometric analysis; chronic pain; electroacupuncture; emotional regulation
    DOI:  https://doi.org/10.3389/fneur.2025.1502657
  37. Photodiagnosis Photodyn Ther. 2025 Mar 05. pii: S1572-1000(25)00063-8. [Epub ahead of print] 104533
    Three Decades of Photodynamic Therapy for Glioblastoma: A Comprehensive Scientometric Analysis.
    Jiheng Zhang, Xiuwei Yan, Xin Gao, Jiahe Hu, Hongtao Zhao, Chengyun Yang, Lei Xu, Yapeng Niu, Mo Geng, Nan Wang, Shaoshan Hu.
       BACKGROUND: Photodynamic therapy (PDT) has emerged as a promising adjunctive treatment for glioblastoma (GBM), yet a comprehensive bibliometric analysis of this field is lacking. This study explores research trends, major contributors, and hotspots in PDT for GBM to provide an integrated overview of its development.
    METHODS: Literature from 1993 to 2024 was retrieved from the Web of Science Core Collection. Bibliometric tools, including CiteSpace, analyzed publication trends, collaborations, and keyword co-occurrence to identify influential authors, institutions, and journals.
    RESULTS: A total of 799 publications showed a growing research interest, peaking in 2022. The United States and China were leading contributors, with prominent institutions like the University of California System and Centre National de la Recherche Scientifique. Influential figures, such as Jiro Akimoto and Walter Stummer, advanced clinical applications and fluorescence-guided techniques. Early studies of photodynamic therapy for GBM have focused on evaluating its efficacy and potential side effects, transitioning towards innovative strategies like targeted drug delivery, nanotechnology, and combination therapies. However, the similarities between early and recent studies are in the search for safe and reliable photosensitizers. Keyword analysis highlighted "5-aminolevulinic acid", "in vitro", and "polyethylene glycol compounds" as key areas, while timeline analysis revealed shifts from foundational photosensitizer research to approaches addressing tumor heterogeneity and resistance.
    CONCLUSIONS: This study provides a systematic overview of PDT research for GBM, spotlighting breakthroughs and collaborative networks. The findings emphasize the importance of preclinical innovation and clinical translation to fully realize PDT's potential in GBM therapy.
    Keywords:  Bibliometric Analysis; Photodynamic Therapy; Photosensitizer Development; Research Trends; glioblastoma
    DOI:  https://doi.org/10.1016/j.pdpdt.2025.104533
  38. Healthcare (Basel). 2025 Feb 20. pii: 441. [Epub ahead of print]13(5):
    Depression and Anxiety in Patients with Psoriasis: A Comprehensive Analysis Combining Bibliometrics, Latent Dirichlet Allocation, and HJ-Biplot.
    Aline Siteneski, Karime Montes-Escobar, Javier de la Hoz-M, German Josuet Lapo-Talledo, Geovanna Gutiérrez Moreno, Esther Carlin Chavez, Rosangela Caicedo Quiroz, Gulnara Patricia Borja-Cabrera.
      Background: Patients with psoriasis often experience psychiatric comorbidities, such as depression and anxiety. These comorbidities can lead to poorer adherence to treatment regimens, reduced effectiveness of therapies, and a heightened disease burden. This study aims to explore the scientific output related to psoriasis, depression, and anxiety using a comprehensive analysis combining bibliometric statistical methods. Methods: The study performed a bibliometric analysis of publications related to psoriasis, depression, and anxiety between 1974 and December 2023. This study employed the Latent Dirichlet Allocation (LDA) algorithm to identify key research topics and used the HJ-Biplot technique to visualize the relationships between publications and research indicators. The inclusion criteria were limited to English-language research articles. Results: Over 49 years, the analysis identified 5059 documents published across 1151 sources. The annual growth rate for research was 12.26%. The Journal of the European Academy of Dermatology and Venereology and The British Journal of Dermatology were found to be the leading journals in this field. The United States emerged as the top contributor, followed by China, Italy, and Germany. The most prevalent research topics were inflammation and cellular function, with a significant focus on patient treatment and the impact of depression and anxiety. Conclusions: This bibliometric analysis underscores the increasing of studies on the comorbidities of depression and anxiety in patients with psoriasis. This study provides a comprehensive overview of research trends and emerging topics in this field, offering valuable insights for future investigations.
    Keywords:  HJ-Biplot; Latent Dirichlet Allocation (LDA); anxiety; bibliometric analysis; depression; psoriasis; psychiatric comorbidity
    DOI:  https://doi.org/10.3390/healthcare13050441
  39. J Contemp Dent Pract. 2024 Dec 01. 25(12): 1172-1178
    Scientometric Mapping of the Flipped Classroom in Dental Education: Geospatial Dynamics, Emergent Patterns, and Networking.
    Fran Espinoza-Carhuancho, Alexander Taquia-Faustino, Lucia Quispe-Tasayco, Arnaldo Munive-Degregori, Katia Medina-Calderon, Frank Mayta-Tovalino.
       AIM: To perform a scientometric mapping of the flipped classroom (FC) in dental education through an analysis of geospatial dynamics, emerging patterns, and collaborative networks.
    MATERIALS AND METHODS: A comprehensive search of the Web of Science database (Core Collection) was conducted on September 1, 2024, using specific terms related to innovative teaching methodologies and dental education. Articles published between January 2005 and September 2024, indexed in Web of Science, and published in English were included. The collected data included article title, authors, year of publication, journal, keywords, and number of citations. Data analysis was conducted using CiteSpace and Bibliometrix to identify publication patterns, emerging trends, and collaborative networks.
    RESULTS: Between 2005 and 2024, 306 documents from 94 sources were analyzed, with an annual growth rate of 20.2%. The average age of the documents was 6.19 years, with an average of 12.47 citations per document and 7,469 references. In total, 701 authors' keywords were identified. A total of 1,183 authors participated, of whom 19 published single-authored papers, resulting in 20 single-authored papers. The average number of coauthors per paper was 4.39, with 18.63% international coauthorships. The main clusters identified were "Flipped Classroom," "COVID-19," and "Curriculum Reform." The years 2019 and 2020 contained the highest number of co-citations, highlighting authors such as Gianoni-Capenakas and Iyer. The three-dimensional structure of the landscape view graph revealed densely connected areas, indicating consolidated research themes.
    CONCLUSION: The results of this study have demonstrated a significant evolution in educational methodologies in dentistry, with an increasing focus on the FC and other educational technologies. The high concentration of publications in key journals and the predominance of authors with a single publication underline the importance of fostering collaborative networks and the dissemination of innovative practices. These findings require alignment with the conclusion mentioned in the main manuscript, as the overall conclusion is very broad and needs to be more specific to reflect the detailed results of the study.
    CLINICAL SIGNIFICANCE: This study mapping the FC in dental education is clinically significant because it has a chance to influence the very nature of teaching methodologies. The study treats geospatial dynamics, emerging patterns, and collaborative networks and has highlighted the further incursion of innovative educational practices. The findings show that continued research and collaboration are needed to further optimize and develop these methodologies for the benefit of both educators and learners in the field of dentistry. How to cite this article: Espinoza-Carhuancho F, Taquia-Faustino A, Quispe-Tasayco L, et al. Scientometric Mapping of the Flipped Classroom in Dental Education: Geospatial Dynamics, Emergent Patterns, and Networking. J Contemp Dent Pract 2024;25(12):1172-1178.
    Keywords:  Dental education; Dental training; Flipped classroom Scientometrics.
    DOI:  https://doi.org/10.5005/jp-journals-10024-3800
  40. Respir Med. 2025 Mar 08. pii: S0954-6111(25)00092-7. [Epub ahead of print]240 108030
    Analysis of research trends and hot spots on COPD biomarkers from the perspective of bibliometrics.
    Ying Liu, Jianliang Huang, Enping Li, Yun Xiao, Chengyou Li, Mingkai Xia, Jun Ke, Lijun Xiang, Mingsheng Lei.
       BACKGROUND: Chronic obstructive pulmonary disease (COPD), a chronic respiratory condition with airflow limitation, is the fourth leading global cause of death. Biomarkers are key for classifying COPD, detecting exacerbations, guiding treatment, and prognosis. This article uses bibliometrics and visualization to analyze COPD biomarker research trends, providing insights for future studies.
    METHODS: This study adopts a range of literature analysis tools, including HistCite, VOSviewer, and CiteSpace, to systematically analyze literature on COPD biomarkers within the Web of Science Core Collection database from 2005 to 2024.
    RESULTS: A total of 1835 papers or reviews related to COPD biomarkers are included in this study. Since 2003, the number of publications in this field has been on an upward trajectory. The United States being most influential in this field (n = 415, TLCS = 2319). Prominent institutions such as the University of British Columbia consistently deliver high-quality research results. Tal-Singer R, Sin DD, and Vestbo J have made significant contributions to COPD biomarker research. The journal American Journal of Respiratory and Critical Care Medicine is the most authoritative choice for researchers in the field.This research has long focused on biomarkers associated with the inflammatory response (C-reactive protein, eosinophils, etc.), pulmonary function, induced sputum, and computed tomography. Looking ahead, biomarkers such as microRNA, exosomes, DNA methylation, and microbiomics are likely to become popular topics, particularly regarding their roles in the prognosis and mechanisms of COPD.
    CONCLUSION: Bibliometric analysis suggests that future research on COPD biomarkers will focus on advanced fields, such as microRNA, exosomes, DNA methylation, and microbiomics.
    Keywords:  Bibliometrics; Biomarkers; COPD; Disease management; microRNA
    DOI:  https://doi.org/10.1016/j.rmed.2025.108030
  41. Medicine (Baltimore). 2025 Mar 07. 104(10): e41739
    Therapeutic potential of triple-negative breast cancer immune checkpoint blockers: A 21-year bibliometric analysis.
    Zhongli Sun, Cun Liu, Yan Yao, Chundi Gao, Huayao Li, Longyun Wang, Ye Li, Changgang Sun.
       BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive metastatic subtype of BC that frequently develops chemoresistance. Immune checkpoint blockers (ICB) have led to breakthroughs in TNBC treatment. This study aimed to explore research trends and public interest in ICB interventions for TNBC.
    METHODS: We searched the Web of Science Core Collection (WoSCC) database for publications related to ICB for TNBC from 2003 to 2024. VOSviewer, CiteSpace, and R package "bibliometrix" were used to analyze the characteristics of ICB publications in TNBC from a quantitative and qualitative perspective and to visualize the results to comprehensively present the research trends in this field.
    RESULTS: After removing duplicates, 2698 publications were included. The New England Journal of Medicine may be the leading and influential in the field of ICB in TNBC according to data on the total number of publications, number of citations, and impact factors. Its article entitled "Atezolizumab and Nab-Paclitaxel in Advanced TNBC" is 1 of the most cited articles. Keyword analysis showed that current research hotspots in this field are tumor microenvironment, complete pathological response, neoadjuvant chemotherapy, and PARP inhibitors. Future research hotspots may include the PD-L1 inhibitor durvalumab and antibody-drug conjugates (ADC).
    CONCLUSIONS: This study revealed that ICB therapy for TNBC is a rapidly evolving and high-profile topic. Future research should focus on the optimal selection of different targets for ICB in combination with neoadjuvant chemotherapy, ADC, and poly ADP-ribose polymerase inhibitors to treat TNBC.
    DOI:  https://doi.org/10.1097/MD.0000000000041739
  42. Healthcare (Basel). 2025 Mar 06. pii: 575. [Epub ahead of print]13(5):
    The Effect of Leisure-Time Exercise on Mental Health Among Adults: A Bibliometric Analysis of Randomized Controlled Trials.
    Karuppasamy Govindasamy, Masilamani Elayaraja, Abderraouf Ben Abderrahman, Koulla Parpa, Borko Katanic, Urs Granacher.
      Background: Adequate levels of leisure-time exercise (LTE) are associated with mental health benefits. Despite increased research in recent years through randomized controlled trials (RCTs), a systematic literature review summarizing these findings is lacking. Here, we examined publication trends, impact, and research gaps regarding LTE's effects on mental health in the form of a bibliometric analysis. Methods: Five electronic databases (PubMed, EMBASE, Web of Science, Ovid Medline, and the Cumulative Index for Nursing and Allied Health Literature) were searched from their inception until 20 November 2024. Citations were independently screened by two authors and included based on pre-determined eligibility criteria. Bibliometric analysis was conducted using SciVal and VOSviewer under five themes: (1) descriptive analysis, (2) network analysis, (3) thematic mapping, (4) co-citation and co-occurrence analysis, and (5) bibliometric coupling. Results: The systematic search identified 5792 citations, of which 78 RCTs met the inclusion criteria. Only one study was conducted in a low- or middle-income country. Sixty-four percent of studies were published in quartile-one journals. Most studies were conducted in the United States, followed by Australia, Canada, and the United Kingdom. National collaborations yielded the highest citation rates, reflecting the influence of cultural and social norms on exercise and mental health. Research gaps were identified with regards to the validity of mental health measures, the paucity of data from low- and middle-income countries, and emerging research sources. Conclusions: This bibliometric analysis highlights the existing evidence on LTE's impact on mental health and identifies areas for future research and policy. Trials exploring valid mental health outcomes, biomarkers such as mood and oxidative stress, and collaborative research are needed, particularly in underrepresented regions of the world.
    Keywords:  bibliometric; depression; leisure time; mental health; physical activity; sustainable cities
    DOI:  https://doi.org/10.3390/healthcare13050575
  43. J Thorac Dis. 2025 Feb 28. 17(2): 796-815
    Emerging trends and hotspots in animal experimental research on lung transplantation from 2004 to 2023: a bibliometric analysis.
    Chen Xie, Mingyi Piao, Liwang Zhou, Xinchen Tao, Yuanyuan Yao, Baochun Jiang, Xinqiang Wang, Min Yan.
       Background: Lung transplantation is the only viable option for end-stage respiratory diseases, with the global prevalence of this procedure on the rise in recent years. However, it is still plagued by various complications, for which no satisfactory therapy has yet been identified. Understanding the mechanisms underlying these post-transplant complications may be beneficial to enhance patient outcomes. This study utilized bibliometric analysis to assess present publication trends and focal points in the field of animal experimental studies on lung transplantation, aiming to provide insights into potential areas for future research.
    Methods: Utilizing CiteSpace software, the Online Analysis Platform of Literature Metrology, R package bibliometrix and VOSviewer, an analysis of current publication trends and hotspots in the area of animal experimental research for lung transplantation was carried out for the period spanning from 2004 to 2023. The English articles were searched in the Science Citation Index-Expanded (SCI-E) of Web of Science Core Collection (WoSCC).
    Results: A total of 995 articles on animal experimental research on lung transplantation over the past two decades were retrieved. Rats, mice and swine were the most commonly used animal models, with orthotopic lung transplantation, ischemia-reperfusion (IR), and ex vivo lung perfusion (EVLP) being the most frequently employed model of lung transplantation in animals. The leading contributed countries in this area were USA, Canada, Japan and China. Washington University and Shaf Keshavjee were acknowledged as the most influential institute and scholar, respectively. The top 10 main clusters identified through co-occurrence cluster analysis included, ex-vivo lung perfusion, EVLP, obliterative bronchiolitis, necroptosis, bronchiolitis obliterans, non-heart-beating donor, donation after circulatory death, xenotransplantation, hydrogen sulfide and alveolar macrophage. Current research focused on lung IR injury, lung transplant, hypoxia, and differentiation, as revealed by keyword burst detection.
    Conclusions: Over the past 20 years, global publications on animal experimental research for lung transplantation have grown rapidly. The current research hotspots focus on lung IR injury, hypoxia and differentiation during lung transplantation. Exploring the potential synergistic effects of EVLP and necroptosis inhibition in more depth could offer valuable information for improving lung transplant outcomes. Our analysis presents a detailed overview of the current state of animal experimental research in lung transplantation, evaluating current publication trends and focal points and providing significant insights for future research efforts.
    Keywords:  CiteSpace; Lung transplantation; animal model; bibliometric analysis; hotspots
    DOI:  https://doi.org/10.21037/jtd-24-1451
  44. Mol Biol Evol. 2025 Mar 11. pii: msaf054. [Epub ahead of print]
    Do manuscripts by female evolutionary biologists spend longer under review?
    David Alvarez-Ponce, James Vesper.
      Women are underrepresented in academia and in STEM careers, especially at senior positions and top institutions. This may be, at least in part, due to the many obstacles that they experience along the academic pipeline. There has been substantial debate as to whether women are treated unfairly during the peer review process. An analysis of over 9000 research articles published in top Economics journals has recently shown that female-authored articles tend to spend 3-6 months longer under review (period from submission to acceptance), and to have more readable abstracts, than male-authored articles, suggesting that female-authored articles are held to higher standards. We set out to determine whether these trends were also present among 49,031 papers published in 11 Evolutionary Biology journals. We found that female representation among article authors substantially increased over the decades. The percentage of women is lower among corresponding authors than among all authors, especially of recent articles. In addition, female first authors were less likely to be corresponding authors than male first authors, and the gender of the first author correlated with the gender of the corresponding author. In some of the journals, female-authored articles spent significantly longer under review; however, most of the observed differences vanish after controlling for the date of publication and the number of authors. In addition, female-authored abstracts are not more readable. Our results suggest that the peer review process in the field of Evolutionary Biology is generally not biased against women.
    Keywords:  Discrimination against women; Evolutionary Biology; Gender inequality; Peer review; Research productivity; Women in Science
    DOI:  https://doi.org/10.1093/molbev/msaf054
  45. World Neurosurg. 2025 Mar 07. pii: S1878-8750(25)00240-2. [Epub ahead of print] 123884
    A Bibliometric Analysis of Sitting Position and Air Embolism in Neurosurgery: Top 100 Most Cited Articles.
    Gökce Hatipoglu Majernik, Mustafa K Baskaya.
       BACKGROUND: The selection of a neurosurgical sitting position (SP) with regard to complication avoidance is a much-debated topic in neurosurgery and anesthesiology. In this bibliometric analysis, we examined the 100 most cited neurosurgical and anesthesiology SP articles focused on posterior fossa surgery.
    METHODS: The Scopus database was searched on January 25, 2025 for key words: "neurosurgery" OR "neurological surgery" OR "anesthesiology" AND variations of "sitting" including: "semisitting", "seated", "half sitting", "halfseated", "upright" and "lounging", and for "air embolism". The 100 most cited of the 2835 articles found were then reviewed in detail.
    RESULTS: The 100 most cited papers were published between 1964-2019. Venous air embolism (VAE) was the most common complication, discussed in 52 articles, with reported VAE incidences varying from 0 to 100% (median 20%). Incidences of paradoxical air embolism (PAE) ranged from 0 to 14% (median 0%) of cases, with mortality related to VAE rates ranging from 0% to 0.5% (median 0%). VAE detection methods differed throughout the years and between institutions, but how VAE was managed was similar in the majority of reports from all institutions. Sixty one percent of SP reports originated from anesthesiology departments and 36% from neurosurgery departments. Nearly all reports were published in anesthesiology (51%) or neurosurgical journals (45%), with only 4% in other journal disciplines.
    CONCLUSION: The use of a SP is often debated in neurosurgery and anesthesiology. This bibliometric analysis summarizes the most cited reports to provide a guide for neurosurgeons and anesthesiologists for diagnostic evaluation, complication avoidance and surgical management.
    Keywords:  air embolism; bibliometric study; positioning; sitting position
    DOI:  https://doi.org/10.1016/j.wneu.2025.123884
  46. Medicine (Baltimore). 2025 Mar 07. 104(10): e39970
    Knowledge map and emerging trends of oxidative stress in wound healing: A bibliometric analysis from 2000 to 2023.
    Fan Bu, Kai Yu, Jinnan Wang, Li Rong, Qiaoyu Li.
      The skin's integrity is vulnerable to external elements that can induce injuries, leading to wound formation. It's crucial to comprehend wound healing processes to protect the body when this protective barrier is compromised. Over the last 2 decades, there has been considerable progress in understanding delayed wound healing, with a focus on the mechanisms and microenvironmental factors involved. The connection between oxidative stress and wound healing has recently gained attention, emphasizing the need for in-depth analysis to propel further advancements and interventions in this area. Despite these advancements, there remains a noticeable void in the literature concerning the application of scientometric methods to systematically examine the progression of wound healing research. Additionally, a comprehensive assessment of the research output and effectiveness of various researchers and institutions in this field is lacking. To address these gaps, we analyzed data from the Web of Science Core Collection from January 1, 2000, to December 31, 2023, utilizing relevant keywords. Using CiteSpace, we created visual maps that depict the evolution and structure of keyword clusters, and both CiteSpace and VOSviewer were used to evaluate the performance of research networks across different countries, institutions, and authors. This data was methodically analyzed. The leading institution in this field is the Chinese Academy of Medical Sciences. The key researchers are Bekeschus, Sander; Li, Yang; Bi, Yang; Fan, Daidi; and Zhang, Yu. Our software analysis reviewed 3025 studies, revealing 19 co-citation clusters that highlight current trends in research on oxidative stress and wound healing. Prominent journals, leading institutions, and key researchers were identified. Key emerging research directions include studying the mechanisms linking oxidative stress to wound healing, exploring the use of antioxidant substances in wound dressings, and investigating how nanomaterials in dressings can influence oxidative stress. These focal points emphasize the significance of understanding oxidative stress's impact on wound healing and investigating new methods to enhance therapeutic efficacy. This comprehensive approach not only fills a gap in the current literature but also sets the stage for future research endeavors in this crucial area of health science.
    DOI:  https://doi.org/10.1097/MD.0000000000039970
  47. Health Sci Rep. 2025 Mar;8(3): e70443
    Scientometric Study of Mpox and Vaccine Research: Dynamics, Emerging Patterns, and Networking.
    Fran Espinoza-Carhuancho, Juan Alvitez, Abigail Temoche, Victor Roman-Lazarte, Frank Mayta-Tovalino.
       Background and Aim: Mpox (Monkeypox) is a zoonotic disease transmitted through contact with infected animals or humans. Recent research focuses on epidemiology, transmission, and vaccine development to combat its resurgence. This bibliometric study analyzed the dynamics, emerging patterns, and networks of mpox and vaccine research from 2019 to 2024.
    Methods: The literature search was conducted in the Scopus database on August 18, 2024, initially identifying 1278 papers published between January 2019 and August 2024. A specific search strategy was applied to collect documents. The retrieved documents were analyzed using the Scival and Bibliometrix tools to obtain bibliometric metrics. Data analysis was performed using R Studio and Scival.
    Results: During the study period, 562 sources were identified that contributed to 1278 papers on mpox and vaccine research. These papers show an impressive annual growth rate of 91.49%. Several institutions stood out for their contributions to mpox and vaccine research. The journal Vaccines had 58 publications, followed by the Journal of Medical Virology and Vaccine with 31 publications each. According to Bradford's law, in Zone 1, the journal Vaccines had 58 publications. According to Lotka's law, most authors in the field of mpox and vaccine research have written only one article.
    Conclusion: These findings highlight the diversity of sources contributing to the mpox and vaccine research literature and highlight the importance of these sources in terms of their scholarly impact and relevance to the research community. This study provides valuable insight into emerging trends and patterns in the field.
    Keywords:  Mpox; bibliometrics; global public health; vaccine
    DOI:  https://doi.org/10.1002/hsr2.70443
  48. Glob Health Action. 2025 Dec;18(1): 2474787
    Exploring socio-economic dimensions in HIV research: a comprehensive bibliometric analysis (1992-2024).
    Lyudmila Yermukhanova, Marat Kuzembayev, Akkumis Salkhanova, Nazerke Narymbayeva, Aigul Tazhiyeva, Dinara Nurgalievna Makhanbetkulova, Alireza Afshar.
      The socio-economic burden of HIV infection remains a critical global health concern. This study was conducted to perform a comprehensive bibliometric analysis of the socio-economic burden of HIV infection, highlighting research trends, collaboration networks, and the evolving focus on social determinants of health over the past 32 years. A systematic search was conducted in Scopus and Web of Science Core Collection databases, covering publications from 1992 to 2024. The analysis was performed using RStudio and Biblioshiny, focusing on 1,054 studies from 422 publications. This study revealed a steady annual growth rate of 16.72% in publications on the socio-economic burden of HIV from 1992 to 2024, with the USA and Canada leading in contributions. The University of Toronto emerged as the top institution, while 'social determinants of health' and 'HIV infections' were identified as pivotal research themes. Collaboration networks were predominantly among high-income countries, with limited engagement from high-burden regions like sub-Saharan Africa. Key journals, such as AIDS and Behavior, were identified as central to advancing the field. Thematic analysis highlighted a shift from biomedical to socio-economic factors, emphasizing the need for equitable global collaboration and research addressing disparities in HIV management. This comprehensive analysis provides valuable insights into the evolving landscape of HIV socio-economic burden research, emphasizing the need for increased collaboration with high-burden regions and a continued focus on addressing social determinants of health in HIV management.
    Keywords:  HIV infection; acquired immunodeficiency syndrome; global health; health status; social determinants of health
    DOI:  https://doi.org/10.1080/16549716.2025.2474787
  49. Subst Abuse Treat Prev Policy. 2025 Mar 10. 20(1): 13
    Global scientific research landscape on binge drinking: a comprehensive bibliometric and visualization analysis of trends, collaborations, and future directions.
    Sa'ed H Zyoud.
       BACKGROUND: Binge drinking constitutes a significant public health concern. Defined as the consumption of five or more alcoholic beverages on a single occasion, binge drinking leads to acute cognitive and motor impairments and is associated with a multitude of detrimental health consequences. Therefore, the aim of this study was to analyse globally published peer-reviewed literature on binge drinking.
    METHODS: A thorough search of the Scopus database was conducted to gather all the relevant research. Keywords related to binge drinking were used to locate a wide range of studies. Specific criteria were subsequently applied to narrow the results, ensuring the inclusion of only the most relevant articles. This process yielded a collection of 2,763 research papers. Finally, a software program called VOSviewer was utilized to analyse and visualize the connections between these studies.
    RESULTS: A bibliometric analysis was performed to investigate trends in binge drinking research literature published between 1980 and 2024. The findings revealed a significant increase in publications (R²=0.916; p < 0.001), with a peak in 2018 (191 articles). The majority (89.65%, n = 2,477) were research articles, followed by review articles (4.74%, n = 131). Authors from 139 countries contributed to binge-drinking research, with the USA (n = 1,550; 56.1%) and the UK (n = 216; 7.82%) leading in the volume of publications. The National Institute on Alcohol Abuse and Alcoholism (n = 65; 2.35%) and the University of North Carolina at Chapel Hill (n = 63; 2.28%) emerged as the main institutional contributors. The National Institute on Alcohol Abuse and Alcoholism in the United States was the main funding source, supporting 599 articles (21.68%), followed by the National Institutes of Health in the United States, with 544 articles (19.69%). In particular, the post-2016 period witnessed a shift in research themes toward mechanistic investigations alongside studies on societal interventions, reflecting a growing focus on mitigating the broader social impact of binge drinking.
    CONCLUSIONS: This study is the first comprehensive analysis of trends in binge drinking research. Over the past decade, binge drinking has increased dramatically, led by the United States, the UK, and Spain. Initially, focused on social and cultural factors, research shifted after 2016 to mechanistic and animal models, shaping future research directions and strategies.
    Keywords:  Bibliometric; Binge drinking; Scopus; VOSviewer; Visualization
    DOI:  https://doi.org/10.1186/s13011-025-00641-1
  50. Front Med (Lausanne). 2025 ;12 1530835
    Bibliometric and visualisation analyses of gastric ulcer knowledge areas and emerging trends, 2004-2024.
    Zijian Liu, Yi Liu, Yang Li, Yuyan Sun, Xiaoxiang Song, Lu Chen, Dan Zhou.
       Background: Gastric ulcers are a form of peptic ulcers that present as ruptures of the mucosal lining of the stomach or the proximal intestinal lining extending beyond the muscularis mucosae, and Helicobacter pylori infection is one of the main causative factors of gastric ulcers. However, the growing incidence of Helicobacter pylori drug resistance and the emergence of specialised ulcers has necessitated continued research on gastric ulcers. This study surveyed global gastric ulcer research over the past two decades with the aim of identifying the major findings and emerging trends in the field.
    Methods: Bibliometric analysis was performed using the search terms 'Gastric ulcer', 'Gastric ulcer disease', 'Gastrohelcoma', and 'Stomach ulcers'. Data were extracted from the Web of Science Core Database (WoSCC) and visualised using CiteSpace software.
    Results: The Journal of Gastroenterology had the most cited papers. The largest number of papers was from the United States. The most frequently cited keywords were 'Helicobacter pylori', 'peptic ulcer', and 'gastric ulcer'.
    Conclusion: The field of gastric ulcer research is rapidly expanding, and the existing research is focused on preventing the occurrence of gastric ulcers, exploring the pathogenesis of gastric ulcers, and identifying new methods of treating gastric ulcers.
    Keywords:  Helicobacter pylori; antibiotic resistance; antioxidant; gastric ulcer; gut microbiota; marginal ulcer; stomach ulcers
    DOI:  https://doi.org/10.3389/fmed.2025.1530835
  51. World J Urol. 2025 Mar 10. 43(1): 158
    The association between obstructive sleep apnea and nocturnal enuresis in children: current advances and research trends.
    Zhaokai Zhou, Zhan Wang, Fu Peng, Shuang Chen, Shuai Yang, Zhengrui Li, Yudi Xu, Hongzhuo Qin, Jiaojiao Wang, Qiong Lu, Ran Xu.
       BACKGROUND: Obstructive sleep apnea (OSA) and nocturnal enuresis (NE) represent two clinically prevalent pediatric disorders that frequently present as comorbidities. OSA, characterized by recurrent upper airway collapse during sleep, and NE, defined as involuntary voiding during sleep, collectively contribute to psychosocial distress in children. Emerging evidence suggests that OSA in children can cause NE through multiple mechanisms, though the pathophysiological interplay involving altered arousal thresholds and hormonal dysregulation remains incompletely elucidated. Herein, we summarized the relationship between OSA and NE and identified mainstream research directions and recent hotspots in the relationship between OSA and NA in children and informed further research.
    MATERIALS AND METHODS: This review searched for original publications on the relationship between OSA and NE in children in the Web of Science Core Collection from 1981 to 2025. Research trends, countries, institutions, journals, authors, highly cited publications, and keywords were analyzed using bibliometrics. Co-citation networks were mapped using VOSviewer, and research hotspots and trends were analyzed using CiteSpace.
    RESULTS: A total of 147 publications were included. The number of publications and related research interest in the relationship between OSA and NE in children has increased globally year after year. Sleep monitoring and multidisciplinary collaboration may be the next hotspot in this field. The occurrence of NE shows a positive correlation with the prevalence of OSA, and children with NE frequently exhibit comorbid sleep-disordered breathing. Adenotonsillectomy has been demonstrated to have therapeutic efficacy as a primary intervention for children with concurrent OSA and NE.
    CONCLUSIONS: The co-morbid association between NE and OSA may have significant adverse effects on the psychophysical health of children. Adenotonsillectomy shows potential for treating children with co-morbid OSA and NE. However, systematic multidisciplinary clinical evaluation remains critical in this patient population. Furthermore, this review will help researchers to identify the mainstream research directions and latest hotspots in the field of the relationship between OSA and NE.
    Keywords:  Adenotonsillectomy; Bibliometric analysis; Children; Comorbidities; Health-related quality of life; Multidisciplinary; Nocturnal enuresis; Obstructive sleep apnea; Pathogenesis
    DOI:  https://doi.org/10.1007/s00345-025-05541-4
  52. JTCVS Open. 2025 Feb;23 369-378
    Research productivity among applicants who matched into an integrated thoracic surgery residency program: A bibliographic review.
    Nika Samadzadeh Tabrizi, Michelle Shen, Alexander D Shapeton, Isha Doshi, Junyi Liu, Thomas Fabian, Patrick Chan.
       Background: Research productivity is an important factor in candidate selection by integrated thoracic surgery residency programs, and thus tracking the research output of applicants who match into an integrated program is necessary. This study sought to examine the research productivity of matched integrated applicants prior to residency and to assess demographic, bibliographic, and institutional variables associated with continued research productivity during residency.
    Methods: Bibliographic records of applicants who matched into an integrated thoracic surgery residency program from 2015 to 2022 were reviewed manually (eg, PubMed/MEDLINE, Scopus, Google Scholar, ResearchGate) to identify studies published up to January 2024. Publications were stratified by publication type and first authorship relative to the applicants' match year. Individuals were analyzed by demographics, medical school ranking, and affiliated residency program research infrastructure.
    Results: A total of 300 matched integrated applicants were identified. Among applicants who matched into an integrated program, the number of total (P = .001) and first-authorship (P = .006) publications prior to residency increased significantly from 2015 to 2022. Over the same period, the rates of total (P = .2) and first-authorship (P = .3) publications during residency remained relatively unchanged. Matched integrated applicants with a higher number of total and first-authorship publications prior to residency had higher rates of total publications (1.17; 95% confidence interval [CI], 1.09-1.25; P < .001) and first-authorship publications (1.19; 95% CI, 1.13-1.26; P < .001) publications during residency.
    Conclusions: Research productivity among applicants who matched into an integrated thoracic surgery residency program from 2015 to 2022 has increased and is a strong predictor of sustained scholarly output during residency.
    Keywords:  academic development; basic science research; cardiothoracic surgery training; integrated thoracic surgery residency; research productivity; scholarly endeavors
    DOI:  https://doi.org/10.1016/j.xjon.2024.11.017
  53. Int J Oral Maxillofac Implants. 2025 Mar 13. 0(0): 1-30
    Bibliometrics of the Dental Implant Literature: Journals, Countries, and Top-Cited Papers.
    Claude Robert, Concepción Shimizu Wilson, Marc Dieb.
       BACKGROUND: One potential consequence of the multiplicity of bibliometric studies on dental implants is the emergence of a multifaceted image of the literature on implantology; hence complicating analysis and comprehension by readers.
    AIM: In order to reduce or correct this distortion and to help readers in their interpretation, we review and analyze the bibliometrics of the dental implant (BDI) literature.
    METHOD: Using multiple keywords related to dental implants using databases and general internet browsers, we collected and investigated 49 bibliometric studies through the lens of participating journals, contributing countries, and top-cited papers.
    RESULTS AND DISCUSSION: The USA, Italy, Brazil, and China appear regularly among the most productive countries; two European countries, Sweden and Switzerland play a major role in the academic and economic landscape of dental implants; and four countries, two Middle-Eastern (Saudi Arabia and Iran) and two Asian (India, South Korea) countries, have emerged in the forefront of implantology. Despite the diversity of goals, tools, and approaches used, three journals, Clinical Oral Implants Research, Clinical Implant Dentistry and Related Research, and the International Journal of Oral and Maxillofacial Implants, are ranked recurrently among the most productive journals in implantology, and most often used in datasets comprised of a selected number of journals by investigators. Additionally, identifying top-cited papers was used to explore the literature on dental implant.
    CONCLUSION: We hope that this study will facilitate researchers, practitioners, politicians, decision-makers, and other actors involved in implantology with their analysis and interpretation of the bibliometric literature on dental implant.
    Keywords:  Bibliometrics; Countries; Dental implants; Implantology; Journals; Top-cited papers
    DOI:  https://doi.org/10.11607/jomi.11243
  54. Front Oncol. 2025 ;15 1511880
    Evolving paradigms in prostate cancer screening: a decade of bibliometric insights and technological advancements.
    Keqiang Chai, Changhong Xu, Jiangwei Man, Yun Deng, Li Yang.
       Objective: Prostate cancer is a major threat to global male health. This study uses bibliometric methods to analyze the dynamics and trends in prostate cancer screening research, with the aim of optimizing screening strategies and informing policy decisions.
    Methods: Utilizing the Web of Science Core Collection database, this study retrieved prostate cancer screening-related literature published between 2014 and 2024, totaling 5,409 articles. Data processing and analysis were conducted using CiteSpace and the Bibliometrix R package, including citation network analysis, co-word analysis, cluster analysis, and trend analysis.
    Results: The analysis revealed the following key findings: (1) Global literature on prostate cancer screening has grown annually, with the United States, Europe, and China leading research activity; (2) Research hotspots include the risks and benefits of prostate-specific antigen (PSA) testing, MRI-based screening technologies, and the use of molecular and genetic biomarkers; (3) Emerging technologies, such as machine learning and nanodiagnostic techniques, are enhancing diagnostic precision and reducing overdiagnosis; (4) Network analysis of collaborations reveals a shift toward transnational and interdisciplinary research, particularly in integrating biomedical and computer science to drive rapid advancements in screening technologies.
    Conclusion: This study confirms the ongoing vibrancy and technological advancement in the global field of prostate cancer screening research, emphasizing the trend towards precision medicine. Future development of prostate cancer screening strategies should focus on risk-adapted screening and the application of novel biomarkers to optimize screening outcomes and reduce unnecessary medical interventions.
    Keywords:  bibliometric analysis; diagnostic technologies; precision medicine; prostate cancer screening; risk stratification
    DOI:  https://doi.org/10.3389/fonc.2025.1511880
  55. Account Res. 2025 Mar 13. 1-36
    Mapping nine decades of research integrity studies (1935-2024): A scientometric analysis.
    Gengyan Tang.
       BACKGROUND: Research integrity is fundamental to responsible research practice. Despite attention, the intellectual structure and evolution of this field remains underexplored. This study maps the knowledge landscape of research integrity, identifying key themes, contributions, and trends.
    METHODS: A scientometric analysis was conducted on 6,895 records from Web of Science and Scopus (1935-2024). CiteSpace facilitated network analysis, including co-authorship, keyword co-occurrence, and co-citation patterns, while burst detection identified topics.
    RESULTS: Research integrity studies have grown significantly since the 1980s, with interdisciplinary collaboration. Keyword and co-citation analyses reveal a shift from early discussions on scientific misconduct to concerns such as open science, AI ethics, and research governance. A collaboration network has emerged, with leading contributions from North America, Europe, and Asia.
    CONCLUSIONS: Research integrity has matured into an interdisciplinary field, reaching academic consensus with growing integration of policies, regulations, and technology. Future research is expected to focus on AI's role in research integrity. Key areas of concern include algorithmic bias, automation ethics, and implications for scholarly publishing. Open science and transparency will remain central, particularly in addressing data fabrication, paper mills, and predatory publishing. Institutional policies will continue evolving, embedding integrity principles into governance and public engagement initiatives.
    Keywords:  Research integrity; knowledge map; research ethics; responsible research; scientometric analysis
    DOI:  https://doi.org/10.1080/08989621.2025.2470860
  56. Mar Pollut Bull. 2025 Mar 12. pii: S0025-326X(25)00294-2. [Epub ahead of print]214 117819
    The impact of salinity on heavy metal accumulation in seaweed.
    Muhamad Syaifudin, Mohamed G Moussa, Tangcheng Li, Hong Du.
      Aquatic heavy metal pollution, driven by industrialization and climate change, threatens marine ecosystems through bioaccumulation. Climate-induced salinity fluctuations influence metal speciation and bioavailability in coastal environments. Seaweeds, crucial for nutrient cycling and economic use, exhibit species-specific metal uptake under varying salinity conditions. This study employs bibliometric analysis to examine research trends from 1995 to 2024 on the impact of salinity on metal accumulation in seaweeds. A search conducted on 8 October 2024 resulted in 242 articles, which were then filtered to 28 relevant studies for analysis. Using the Web of Science Core Collection, these articles were analyzed with VOSviewer and Bibliometrix to identify key contributors, collaborations, and research themes. Results reveal a growing academic interest since 2006, with increasing citation counts reflecting global concern over salinity and heavy metal pollution. Significant contributions from Brazil and Portugal, alongside strong European collaborations, highlight regional strengths. Five key themes emerge, encompassing seaweed physiology, biomonitoring, and phytoremediation. Findings indicate that salinity fluctuations significantly affect metal bioavailability and uptake in seaweeds, influenced by species-specific factors, temperature, and pH. This study highlights the need for targeted, site-specific research on diverse seaweed species to effectively manage heavy metal pollution in coastal ecosystems, particularly in light of climate change and industrial activities. Additionally, the research emphasizes the potential of seaweeds as bioindicators and bioremediators in environmental monitoring and pollution management.
    Keywords:  Bibliometric analysis; Bioaccumulation and; Heavy metal; Macroalgae; Salinity
    DOI:  https://doi.org/10.1016/j.marpolbul.2025.117819
  57. Dig Dis Sci. 2025 Mar 10.
    Mapping Research Trends in Alcoholic Liver Disease: A Bibliometric Perspective.
    Salvatore Pezzino, Sergio Castorina.
      
    Keywords:  Alcoholic liver disease; Bibliometric; Data-mining; Gut-liver axis; Inflammation; Oxidative stress
    DOI:  https://doi.org/10.1007/s10620-025-08948-6
  58. J Diabetes Metab Disord. 2025 Jun;24(1): 78
    Mapping the landscape of vitamin D in cancer studies: a systematic global investigation.
    Ali Faryabi, Mohammad Amin Salari, Alaleh Dalvand, Hassan Akbarniakhaky, Ghazal Mohammadi, Hossein Aazami, Farideh Razi, Hojat Dehghanbanadaki.
       Purpose: This comprehensive study examines the multifaceted relationship between vitamin D and cancer, synthesizing key scientific advancements and global research trends to guide future investigations and address critical gaps in the field.
    Methods: Publications on vitamin D and cancer were retrieved from Scopus up to November 2024. English-language original and review articles were analyzed using Excel, VOSviewer, and Scimago Graphica, focusing on publication trends, citation impacts, and research themes.
    Results: A total of 11,442 publications (80.01% original articles, 19.98% reviews; 51.24% open access) were analyzed. The United States of America led in publications (38.3%) and citations (56.2%), followed by China (7.7%) and the United Kingdom (7.2%) in output, and the United Kingdom (10.6%) and Germany (6.4%) in citations. Countries with the highest citations per document were Belgium (103.4), Slovenia (87.9), and Puerto Rico (76.6). The most frequently studied cancers in relation to vitamin D were breast, colorectal, prostate, skin, lung, ovarian, pancreatic, gastric, hepatocellular, thyroid, leukemia, multiple myeloma, bladder, lymphoma, osteosarcoma, cervical, endometrial, and glioblastoma, respectively. Cluster analysis revealed key patterns related to vitamin D: Calcitriol's chemopreventive role in breast, prostate, and colorectal cancers, dietary vitamin D for its involvement in ovarian cancer, vitamin D for regulation of cancer-related hypercalcemia, vitamin D deficiency links to inflammation-obesity-cancer risk, VDR polymorphisms affecting outcomes in lung and colorectal cancers, and vitamin D's photoprotective effects on skin malignancies, and vitamin D in ulcerative colitis-related cancer. The most cited articles emphasized optimal vitamin D levels and cancer prevention.
    Conclusion: This study highlights the extensive research on vitamin D and its complex links to cancer, emphasizing future prospects with a focus on precision medicine approaches, including targeted supplementation and genomic analyses, to better address individual variability in cancer prevention and treatment.
    Keywords:  Bibliometric; Cancer; Mapping; Scientometric; Trend; Vitamin D
    DOI:  https://doi.org/10.1007/s40200-025-01594-9
  59. Arch Prev Riesgos Labor. 2025 Jan 15. 28(1): 99-102
    [Bibliometric Study and Network Mapping of Teacher Technostress Between 1992-2022].
    Rita Louzán Mariño.
      Interview with Rita Louzán.
    DOI:  https://doi.org/10.12961/aprl.2025.28.01.09
  60. Front Nutr. 2025 ;12 1502720
    Cranberry-derived bioactives for the prevention and treatment of urinary tract infections: antimicrobial mechanisms and global research trends in nutraceutical applications.
    Himanshu Jangid, Amrullah Shidiki, Gaurav Kumar.
       Introduction: Urinary tract infections (UTIs) are a global health concern, increasingly complicated by antibiotic resistance. Cranberry-derived bioactive compounds, particularly proanthocyanidins (PACs), have emerged as a promising non-antibiotic strategy for UTI prevention. This review examines their efficacy, mechanisms of action, and the evolving research landscape through bibliometric analysis.
    Methods: A comprehensive literature review was conducted to assess the role of cranberry metabolites in UTI prevention, focusing on anti-adhesive and antimicrobial mechanisms. Additionally, a bibliometric analysis of publications from 1962 to 2024 was performed to evaluate research trends, collaboration networks, and thematic developments.
    Results: Cranberry metabolites, particularly A-type PACs, flavonoids, and phenolic acids, inhibit Escherichia coli adhesion to urothelial cells, reducing UTI recurrence. Gut microbiota-driven transformation of PACs into bioactive metabolites enhances their efficacy, while cranberry oligosaccharides disrupt biofilm formation in high-risk populations. Bibliometric analysis reveals a surge in research interest post-2000, with increasing global collaborations and a focus on clinical applications.
    Discussion and conclusion: Cranberry bioactives demonstrate significant potential in UTI management, yet variations in formulation, dosage, and metabolic bioavailability present challenges. The growing research interest underscores the need for standardized clinical studies to optimize therapeutic efficacy and establish evidence-based guidelines for their use.
    Keywords:  bibliometric analysis; bioactive compounds; cranberry; functional foods; metabolites; nutraceuticals; proanthocyanidins; urinary tract infections
    DOI:  https://doi.org/10.3389/fnut.2025.1502720
  61. Anaesth Crit Care Pain Med. 2025 Mar 12. pii: S2352-5568(25)00036-0. [Epub ahead of print] 101504
    Gender imbalance in critical care medicine journals.
    Cristina Santonocito, Martina Maria Giambra, Maria Grazia Lumia, Filippo Sanfilippo, Vittorio Del Fabbro, Francesca Rubulotta, Elena Giovanna Bignami, Domenico Abelardo, Jean-Yves Lefrant, Jordi Rello.
       INTRODUCTION: The present study aimed at assessing gender balance in the Editorial roles of Critical Care Medicine (CCM) journals.
    METHODS: A cross-sectional survey was performed for assessing the gender distribution in Editorial Board (EB) roles of journals indexed under Clarivate Journal Citation Reports and Scimago Journal & Country Rank. The influences of editorial roles and of journal rank (separated in quartiles) on gender balance were also assessed.
    RESULTS: Among 99 screened CCM journals, 92 journals were included. There were 937 women among 4002 EB members (23.4%). We found a greater imbalance among Editors-in-Chief (females: n = 12/104, 11.5%) as compared to editorial roles with lower responsibilities (Senior Editors, n = 22/104, 21.2%, p = 0.04; Associate Editors, n = 208/739, 28.1%, p = 0.0002; EB members, n = 695/3055, 22.7%, p = 0.0038). In a post-hoc analysis conducted separating the journals according to their ranking quartiles (1-2 vs 3-4), we found no influence of ranking on gender balance. When exploring the gender balance according to the journals' impact factor, there was a majority of men as editors in all 4 quartiles across all EB roles.
    CONCLUSIONS: We found a large gap in gender distribution across EB members' roles in CCM journals, especially in the role of Editor-in-Chief, regardless of the journal ranking.
    Keywords:  Critical Care Medicine journals; Editorial Board; Gender gap; diversity; inclusion.
    DOI:  https://doi.org/10.1016/j.accpm.2025.101504
  62. Perioper Med (Lond). 2025 Mar 13. 14(1): 29
    National Institute of Academic Anaesthesia (NIAA) research grants: analysis of awardee characteristics and preliminary grant outputs.
    Naomi Watson, Gudrun Kunst.
       BACKGROUND: The National Institute of Academic Anaesthesia (NIAA) is a major UK-based funder of academic anaesthesia and perioperative medicine. It holds two grant rounds per year. Since 2019, research outputs have been collected via a widely used online platform, enabling assessment of grant impact. The aim of our study was to report the characteristics of funding awards and awardees, including equality, diversity, and inclusion (EDI) data.
    METHODS: We conducted a retrospective analysis of NIAA grant data submitted by award holders (2019-2023) and assessed EDI characteristics for all applicants and recipients, collected since 2022. The primary objective was to assess grants by geographical distribution, type of institutions and research category. Secondary objectives included preliminary grant outputs and EDI characteristics of applicants and awardees.
    RESULTS: Between 2019 and 2023, 63 grants totalling £2,488,857 were awarded. Grants were well-distributed across the UK and Ireland, with London-based research groups receiving the most (n = 16, 25%) and securing £825,591 (33% of total funding). University-affiliated institutions received 38 grants (60%), while 25 grants (40%) were awarded to teaching and non-teaching hospitals. By research type, pre-clinical studies received 41% of funding (n = 26), followed by clinical observational (24%, n = 15), clinical interventional (14%, n = 9), and epidemiological studies (13%, n = 8). Fifty-one publications have been reported by 20 principal investigators across 30 journals, with a total of 1723 citations and a median of 17 citations per paper. More than half (n = 28, 55%) were published in journals with an impact factor of 7 or higher. Most applicants were white, heterosexual males, but no EDI characteristic was significantly associated with application success.
    CONCLUSION: NIAA grants were geographically diverse and supported a broad range of research types. Most funded research was published in high-impact journals. However, a notable lack of diversity was observed among applicants, both successful and unsuccessful. Future NIAA strategies should focus on increasing diversity and representation among grant applicants.
    DOI:  https://doi.org/10.1186/s13741-025-00505-z
  63. J Craniofac Surg. 2025 Mar 10.
    The Use of Synthetic Dermal Matrix in Lower Eyelid Reconstruction: Our Surgical Management and a Bibliometric and Visual Analysis.
    Stefania Troise, Federica Calabria, Andrea Bagnato, Antonio Arena, Giovanni Salzano, Vincenzo Abbate, Giovanni Dell'Aversana Orabona, Paola Bonavolontà.
      Eyelid defects, particularly those affecting the medial canthus, present intricate challenges for reconstructive surgeons due to the complex anatomy and functional significance of the region. This article presents our management of an 87-year-old patient with medial canthal basal cell carcinoma, highlighting the successful management of such defects through a single-stage reconstruction technique involving a skin graft supported by a synthetic dermal matrix (MatriDerm). The utilization of this approach resulted in favorable outcomes, including clear margins on histological examination and stable esthetic results at 1-year follow-up, emphasizing its efficacy in addressing medial canthal defects secondary to basal cell carcinoma excision. In addition, this study integrates a bibliometric analysis to provide insights into the current research landscape surrounding eyelid reconstruction techniques with the support of dermal matrices. The analysis reveals several trends such as the concentration of research activity in countries like the United States and China, along with key authors and journals contributing to the field. These findings offer valuable guidance for future research endeavors and highlight the global interest in advancing eyelid reconstruction procedures. While this study provides significant insights, it is important to acknowledge its limitations, such as the reliance on a single-day database search and the exclusion of additional databases as potential sources. Future research should have as a goal addressing these limitations and exploring additional routes for a comprehensive literature review. In conclusion, the combination of our described approach and bibliometric analyses offers a comprehensive understanding of eyelid reconstruction, providing valuable insights for clinicians and researchers alike. Sustained collaboration and innovation in this field are essential for further improving surgical techniques and enhancing patient outcomes in reconstructive surgery. Through the synthesis of quantitative data and visualization of network structures, this study contributes to evidence-based practice and guides future research endeavors in eyelid reconstruction.
    DOI:  https://doi.org/10.1097/SCS.0000000000011214
  64. Cureus. 2025 Feb;17(2): e78839
    Investigating the Impact of Resident Doctor Regional Research Meetings on Research Outcomes: A 20-Year Longitudinal Analysis of the Regional Bardhan Fellowship Day.
    Arkadeep Dhali, Olufunmilola Oni, Mohamed G Shiha, Suneil A Raju, Flora Kokwaro, Andrew Nelson, Matthew Huggett, Sampath Kumar, David S Sanders.
      Introduction Medical research plays a critical role in advancing medical knowledge and improving patient care. However, recent studies indicate a decline in trainee participation in research activities. The Yorkshire and Humber regional trainee Bardhan Fellowship was established to address this issue by encouraging and motivating gastroenterology trainees to engage in research. This study aims to evaluate the outcomes of abstracts presented at this regional annual gastroenterology conference. Methods Over the past 20 years, data collection has been conducted using three primary methods. A questionnaire was distributed to gather feedback and ratings from the participants. Additionally, final meeting programs were analyzed to identify abstracts and their respective presenters, including those ranked in the top three. A cross-referencing approach was employed to track subsequent publications of presented abstracts using Web of Science and Medical Literature Analysis and Retrieval System Online (MEDLINE) databases. Results An analysis of 259 abstracts revealed that 91 (35%) were published as full papers in peer-reviewed journals, whereas 168 (65%) remained unpublished. Of the 67 top-three ranked abstracts, 38 (57%) achieved full publication, a significantly higher rate than the 52 (27%) among the 192 unranked abstracts (p<0.0001). The median time to publication for the 67 ranked abstracts was 12.5 months (interquartile range {IQR}: 6.25-21.25 months), compared to 15 months (IQR: 6-27 months) for the 192 unranked abstracts. Ranked abstracts were published in journals with a median impact factor of 3.769 (IQR: 2.491-7.527; p<0.0001), while unranked abstracts were published in journals with a median impact factor of 2.884 (IQR: 1.95-4.628; p<0.0001). Ranked presenters were more likely to receive higher research degrees (26/39 {67%} versus 33/73 {45%}, p=0.03) and were more likely to be employed in a university tertiary care setting (28/41 {68%} versus 34/77 {44%}, p=0.02). Questionnaire data from 161 attendees over nine years indicated a positive evaluation of the meeting. Conclusion Research training conferences are well received by resident doctors and help them develop their research and presentation skills. This conference model could be implemented in other regions to promote research dissemination among resident doctors.
    Keywords:  academia; curriculum; gastroenterology; regional teaching; research fellowship
    DOI:  https://doi.org/10.7759/cureus.78839
  65. Animals (Basel). 2025 Feb 26. pii: 681. [Epub ahead of print]15(5):
    Hotspot Analysis of Rumen Microbiota and Methane Mitigation in Ruminants: A Bibliometric Analysis from 1998 to 2023.
    Xueyue Zheng, Lijie Tang, Rong Wang, Xiumin Zhang, Min Wang, Duanqin Wu.
      Methane (CH4) is the second-most abundant greenhouse gas, following carbon dioxide (CO2), and has a warming potential 28 times greater than CO2 [...].
    Keywords:  bibliometrics; greenhouse gas; methane emission; rumen microbiota
    DOI:  https://doi.org/10.3390/ani15050681
  66. Am J Rhinol Allergy. 2025 Mar 11. 19458924251324238
    Two Decades at 21%: Unchanging Gender Disparities in Rhinology Fellowships.
    Taylor J Stack, Morgan N McCain, Samuel P O'Rourke, Nina Westcott, Theresa Dickerson, Cristine Klatt-Cromwell, Brian D Thorp, Brent A Senior, Charles S Ebert, Adam J Kimple.
      BackgroundThe representation of women in otolaryngology has increased significantly over recent decades, yet discrepancies remain in certain subspecialties, including rhinology. Despite overall improvements in gender equity within otolaryngology, the specific demographic trends and scholarly productivity of fellowship-trained rhinologists have not been thoroughly examined.ObjectiveWe aimed to address this gap by examining demographic trends and academic productivity among rhinology fellowship graduates.MethodsThis cross-sectional study examined publicly available data to analyze fellowship-trained rhinologists in the United States, focusing on gender, career stage, practice setting, h-index, and academic rank. Statistical analyses included Fischer's exact test, Wilcoxon rank sum test, ANOVA, and η2.ResultsWe included 477 fellowship-trained rhinologists who trained at 31 fellowships. No gender differences in career stage or practice type were found. Despite an absolute increase in women per year (0 to 9, η2 = 0.65), the percentage of women in rhinology fellowships has plateaued since 2002 (η2 = 0.001), averaging 21.1% (SD = 10.8%). Most fellowship-trained rhinologists were mid-career, with a median of 7 practice years; 55% worked in academics, mainly as assistant professors. Overall, women rhinologists had a slightly lower h-index than men (7 vs 9; P = .01), but when stratified by academic rank, there was no difference in h-index between men and women.ConclusionThe percentage of women fellowship-trained rhinologists has not increased since 2002 (η2 = 0.001), remaining at a mean of 21.1%. Contrasting with other subspecialties, women and men rhinologists have similar h-indices by academic rank. However, there are still fewer women in rhinology overall than men.
    Keywords:  DEI; academic rank; fellowship; gender; gender equity; gender trends; h-index; inclusion; scholarly productivity; training
    DOI:  https://doi.org/10.1177/19458924251324238
  67. JAMA Otolaryngol Head Neck Surg. 2025 Mar 13.
    Retractions in Otolaryngology Publications.
    Shaun Edalati, Tony Chung, Maya Govindaraj, Daniel Kraft, David K Lerner, Anthony Del Signore, Alfred Marc Iloreta.
       Objective: To characterize trends in otolaryngology (ear, nose, and throat [ENT]) retractions, identify underlying causes, and compare retraction rates with similar specialties.
    Design, Setting, and Participants: A scoping review of retracted articles published from January 1, 1974, through December 31, 2023, was carried out. Retraction data were obtained from the Crossref/Retraction Watch database and corresponding abstracts were retrieved from PubMed. Publication data were obtained from Scopus. All retracted articles related to ENT were identified. Articles from neurosurgery and ophthalmology were similarly retrieved for comparison. Articles withdrawn for routine updates, expressions of concern, reinstatements, and corrections were excluded. The data were obtained on December 3, 2024.
    Main Outcomes and Measures: The primary outcomes were annual retraction rate (proportion of retracted articles per total published articles) and reasons for retraction (categorized as intentional data misconduct, intentional procedural misconduct, unintentional data errors, unintentional procedural errors, or unknown). Secondary measures included time from publication to retraction and comparisons with neurosurgery and ophthalmology retraction rates.
    Results: Of 481 215 ENT articles, 471 (0.10%) were retracted. Retractions increased over time, peaking in 2022 with a retraction rate of 0.42%. Among retracted ENT articles, the most common reasons were intentional data misconduct (233 [49.50%]) and intentional procedural misconduct (210 [44.60%]). Articles with first authors from China accounted for the largest share (243 [51.60%]) of these retractions. Basic science head and neck cancer research represented the largest subspecialty category (161 [34.20%]). The median (IQR) time to retraction was 21.8 (10.8-55.3) months.
    Conclusions and Relevance: This analysis found that retractions in ENT literature have increased over 5 decades, predominantly driven by intentional misconduct. These findings highlight the need for enhanced oversight, training, and editorial vigilance to maintain the integrity of ENT research and protect patient welfare.
    DOI:  https://doi.org/10.1001/jamaoto.2025.0018
  68. FEBS Lett. 2025 Mar 08.
    Leaving science-attrition of biologists in 38 OECD countries.
    Marek Kwiek, Lukasz Szymula.
      We examine biologists leaving science in 38 OECD countries in the past two decades. In a cohort-based and longitudinal fashion, we follow individuals over time, from their first publication (N = 86 178). We examine four disciplines: AGRI (agricultural, biological sciences), BIO (biochemistry, genetics, molecular biology), IMMU (immunology, microbiology), and NEURO (neuroscience). Our Kaplan-Meier survival analysis of BIO shows that 60% of women are still in science after 5 years, 40% after 10 years, and only 20% after 19 years. Women in BIO are 23.26% more likely than men to leave science after 10 years and 39.74% after 19 years. Gender differences increase consistently in later career stages. They are high, but comparing the 2000 and 2010 cohorts, have slightly decreased over time.
    Keywords:  Kaplan–Meier estimator; Scopus; academic careers; attrition and retention in science; biochemistry; biology; gender disparities; genetics; immunology; microbiology; molecular biology; neuroscience; science of science; survival analysis
    DOI:  https://doi.org/10.1002/1873-3468.70028
  69. J ISAKOS. 2025 Mar 05. pii: S2059-7754(25)00463-8. [Epub ahead of print] 100846
    The Limited Impact of Randomized Controlled Trials on the Management of Greater Trochanteric Pain Syndrome as Demonstrated by Fragility Indices: A Citation Analysis.
    David Slawaska-Eng, Alexandre Veilleux, Arthur Thebaud, Yoan Bougeault-Gagnon, Mansi Patel, Hassaan Abdel Khalik, Olufemi R Ayeni.
       IMPORTANCE: Greater trochanteric pain syndrome (GTPS) is a chronic condition commonly defined as pain in the lateral hip joint that can be severely limiting to activities of daily living, sleep, and overall quality of life. It encompasses numerous disease states causing pain in the region of the greater trochanter of the femur. Non-invasive management approaches of GTPS include corticosteroid injections and physiotherapy, preferred as first-line interventions prior to surgical interventions. Understanding the impact of randomized control trials (RCTs) can enhance understanding of treatment paradigms.
    OBJECTIVE: To identify factors and study characteristics associated with the impact, as measured by the citation density of RCTs in the management of GTPS.
    EVIDENCE REVIEW: MEDLINE, EMBASE, CENTRAL, SCOPUS, and Web of Science were searched from database inception to September 5th, 2023 for 'RCTs evaluating conservative and surgical interventions for GTPS. The inclusion criteria for this systematic review were level I evidence, assessment of at least two different approaches to the management of GTPS, published in English, and featuring human subjects. Pertinent study characteristics were extracted from the included trials after title/abstract and full-text screening. Citation metrics were obtained from the Clarivate Web of Knowledge database on September 28th, 2023. The fragility index (FI) and continuous fragility index (CFI) were calculated for primary outcomes across all included RCTs. Univariate regression models were used to assess correlations between citation density and a variety of study characteristics. A sub-analysis by category of intervention (injectable modalities, non-invasive modalities, and surgical modalities) was also performed, with an ANOVA of study and bibliometric characteristics.
    FINDINGS: Twenty-one studies published from 2009 to 2023 comprising 1683 patients (1690 hips) met inclusion criteria and were eligible for analysis. Treatments ranged from non-invasive (n = 8), injectable (n = 12), to surgical modalities (n = 1). Eleven different countries were represented amongst the included RCTs; 71.4% were from the United States or Europe, with the remaining 28.6% originating from Australia. The median journal impact factor of published studies was 3.4 (IQR 2.4 - 4.8). The mean citation density across all three intervention categories were injectable modalities (4.37 ± 3.39), non-invasive modalities (3.27 ± 1.77), and surgical modalities (1, not applicable). The median CFI was 2 (IQR 0 - 12). Correlation analysis demonstrated a statistically significant correlation to year published (R = -0.473, p = 0.03) and study sample size (R = 0.735, p < 0.01).
    CONCLUSIONS AND RELEVANCE: RCTs assessing the management of GTPS demonstrate a varied range of clinical uptake, as evidenced by citation density. An array of different healthcare disciplines is involved in GTPS management, signified by the diversity of journals publishing RCTs on the topic. The median CFI is low compared to other citation analyses in orthopedics, demonstrating that the collective conclusions drawn by these studies are limited by fragility. Additionally, RCTs on surgical treatments for cases refractory to nonsurgical management are notably underrepresented, highlighting the necessity for further evaluation.
    LEVEL OF EVIDENCE: I.
    Keywords:  GTPS; citation analysis; gluteal tendinopathy; gluteus medius tendinopathy; gluteus minimus tendinopathy; greater trochanteric pain syndrome; trochanteric bursitis
    DOI:  https://doi.org/10.1016/j.jisako.2025.100846
  70. ANZ J Surg. 2025 Mar 10.
    Abstracts to articles: Examining the publication of presentations at the New Zealand Association of Plastic Surgeons Annual Scientific Meetings.
    Daniel Wen, Hyok Jun Kwon.
       BACKGROUND: The New Zealand Association of Plastic Surgeons (NZAPS) hosts an annual scientific meeting (ASM) to bring clinicians and researchers together to discuss the latest advancements in plastic surgery and showcase the results of up-to-date research through podium and poster presentations. However, it is unclear if these presentations ultimately achieve publication into a peer-reviewed journal. This study aimed to identify the proportion of conference abstracts which are successfully converted to formal journal articles and specifically investigating the effect of variables such as the presenter's training level and country of origin, presentation type and topic, and time to publication.
    METHODS: NZAPS ASM conference programmes from 2016 to 2021 were reviewed to identify all research presentations. Desired information was extracted such as presentation type, presenting author, the presentation sub-specialty topic and presenting author country of origin.
    RESULTS: Out of the 252 abstracts, 24.6% of abstracts had an associated publication with a statistically significant variation depending on the training level of the presenter. Out of the 62 published abstracts, 33.9% were published prior to conference presentation. Accounting for this, the true conversion rate of abstracts to publication after conference presentation was 16.3%.
    CONCLUSION: Abstracts presented at the NZAPS ASM have a modest publication and conversion rate after presentation. The multi-ethnic populations in Australia and New Zealand produce studies that may not be directly applicable to overseas populations; however, this underscores the importance of establishing and maintaining regional journals to facilitate the publication of local research.
    Keywords:  abstract; plastic and reconstructive surgery; plastic surgery
    DOI:  https://doi.org/10.1111/ans.70026
  71. BJPsych Open. 2025 Mar 12. 11(2): e49
    Representation of women in scientific subjects: overview of systematic reviews investigating career progress in academic publishing with a focus on mental health.
    Til Wykes, Sanchita Garg, Daniel Stahl, Ayse Kostem, Emma Wilson-Lemoine.
       BACKGROUND: Women's authorship position in science, technology, engineering, mathematics and medicine research reflects career progression, especially the transition from first to last (usually senior) author. Employment of women in mental health sciences has increased, and so should have had an impact on the change to senior author position.
    AIMS: To identify if first or last women's authorship has changed, and mental health has better representation.
    METHOD: We investigated women's authorship position in a systematic review and meta-analyses, following PRISMA guidelines and using random-effects regression analyses.
    RESULTS: We identified 149 studies with sampling periods from 1975 to 2020 (excluding potential COVID-19 pandemic effects) that showed a large variation of women authors, and found an average proportion for first (26.2%) and last (16.1%) author position. In mental health (psychology and psychiatry), there was a higher representation, with 40% first author and 36.7% last author position, whereas medicine was 25.9% and 19.5%, respectively. The rate of change for psychology and psychiatry women authors was also higher every 10 years: 8.56% (95% CI 6.44-10.69%) for first and 6.86% (95% CI 4.57-9.15%) for last author, and rate was 2.35% higher for first author and 2.65% higher for last author than in medicine. Different methods of classifying gender and identification method did not affect our results.
    CONCLUSIONS: Although mental health topics seem to fare better, our comprehensive review highlighted that the proportions of women first compared with last authors shows the same leaky pipeline as in other analyses, so we cannot be complacent about gender equality and career progression.
    Keywords:  Career; Science, Technology and Engineering; gender; glass ceiling; sex
    DOI:  https://doi.org/10.1192/bjo.2024.820
  72. Phys Sportsmed. 2025 Mar 14. 1-6
    Gender trends at the annual meetings of two major Japanese societies of sports medicine: a 17-year summary of annual meeting moderators and speakers.
    Aguri Kamitani, Yuka Tsukahara, Katherine H Rizzone.
       OBJECTIVES: To assess for gender disparity among invited moderators and speakers at two major sports medicine conferences in Japan.
    METHODS: The moderators and invited speakers of the Japanese Society of Clinical Sports Medicine (JSCSM) (2008-2023) and the Japanese Orthopaedic Society for Sports Medicine (JOSSM) (2007-2023) were categorized by gender. Gender was determined by searching the Ministry of Health, Labor, and Welfare physician website and then confirmed using a Google search. Fisher's exact tests were used to evaluate the gender distribution. Cochran-Armitage trend tests were used to evaluate changes in gender distribution over time.
    RESULTS: In the past 17 years, neither JSCSM or JOSSM had a woman moderator or speaker in Program Chair's lectures. Between 2018 and 2023, the number of women moderators (n = 59) at JSCSM conference was 1.41% of the total women members (n = 4177), which is significantly lower than 2.22% men moderators (n = 544) out of total men membership (n = 24397), (p < .001). Between 2007 and 2023, the number of women moderators (n = 28) at JOSSM was 1.82% of the total women members (n = 1536), which is significantly lower than 5.91% men who were moderators (n = 1809) out of the total membership of men (n = 30595), (p < 0.001). Since 2008, there was an 11.4% increase in women moderators at JSCSM conferences (1.9% in 2008 to 13.3% in 2023, p-value for trend < 0.001), with a more modest increase of 2.3% at JOSSM conferences (0% in 2007 to 2.3% in 2023, p-value for trend < 0.001). There were similar increases in women invited speakers for JSCSM (14.1% in 2008 to 16.9% in 2023, p-value for trend = 0.001) and for JOSSM (1.2% in 2007 to 3.7% in 2023, p-value for trend = 0.04).
    CONCLUSION: Although both Japanese orthopedic sports medical societies showed increasing trends in the percentage of women in prominent speaking roles, women speakers and moderators are still rare at the Japanese sports conferences.
    Keywords:  Japan; academic conferences; gender disparity; gender gap; sexism; sports medicine
    DOI:  https://doi.org/10.1080/00913847.2025.2477978
  73. Front Oral Health. 2025 ;6 1373404
    Gender equality among medical and dental academic researchers in West Africa: a theoretical analysis of a compendium of research.
    Moréniké Oluwátóyìn Foláyan, Ana Gascón-Catalán, Guillermo Z Martínez-Pérez.
       Background: This study conducted theoretical analyses of the findings of a study on gender disparities in research productivity and leadership in medical and dental research institutions in Nigeria. The aim was to highlight the connectedness of the study findings, and to develop a conceptual framework that can inform future studies on gender equity in academia across West Africa.
    Methods: A content analysis of the research outputs was conducted using four theoretical frameworks to assess the alignment of the study findings with gender equality goals. The research examined policy effectiveness and institutional practices using the 2008 USAID Gender Equality Framework; analyzed how personal traits, societal expectations, and organizational practices intersect using Fagenson's Theory of Gender and Career Development; uncovered gendered power dynamics and inform strategies for institutional reform using the Feminist Institutionalism Analytical Lens; and shed light on disparities in mentorship, collaboration, and academic publishing using the Academic Literacies Theory.
    Results: The key domains influencing gender inequality and requiring targeted actions are: first, the patriarchal societal, cultural, and religious values that shape gender roles, restricting women's career advancement. Second, institutional policies and organizational culture that limits female leadership and research productivity. Third, individual and generational perspectives influence advocacy, with younger individuals recognizing inequality more readily. Research productivity and leadership disparities can be addressed through mentorship and training programs for early-career researchers that foster the development of gender-sensitive advocates. The developed conceptual framework outlines three core research and action domains-societal, institutional, and individual factors-and their sub-factors, alongside targeted interventions influencing gender inequality, proposed targeted recommendations and expected outcomes.
    Conclusions: The findings emphasize the multifaceted nature of gender disparities. Strategic actions are needed to address the issues that foster gender equality in medical and dental research institutions, and to support female researchers in West Africa. These actions should focus on the younger generations to drive needed changes.
    Keywords:  Nigeria; West Africa; gender; inequality; leadership; research productivity; theoretical frameworks
    DOI:  https://doi.org/10.3389/froh.2025.1373404
  74. J Clin Apher. 2025 Apr;40(2): e70015
    Gender Composition of Invited Speakers and Session Chairs at American Society for Apheresis Annual Meetings Between 2019 and 2024.
    Jeremy W Jacobs, Elizabeth S Allen, Laura D Stephens, Brian D Adkins, Jennifer S Woo, Allison P Wheeler, Deva Sharma, Yvette M Miller, Garrett S Booth.
      Disparities persist throughout medicine, including among conference speakership invitations. The National Institutes of Health have highlighted the importance of diversity at academic conferences. We assessed the gender composition of speakers at the American Society for Apheresis (ASFA) annual meeting. We assessed all session chairs and speakers at the annual ASFA meeting from 2019 to 2024. Two authors independently assessed individuals' genders. The primary outcome was the gender composition of all session chairs and speakers by position. Subset analyzes were performed to assess the gender composition of unique individuals (i.e., examining the total number of unique men and women, independent of the number of sessions at which they spoke) and by professional degree. 820 positions (665 speaker positions and 155 chair positions) were identified; women comprised significantly more positions than men [64.3%, 528/820 (95% CI 61.1%-67.6%) vs. 35.6% 292/820 (32.4%-38.9%); p < 0.0001]. 52.7% (432/820) of all session positions were held by physicians, with no significant difference in the gender composition [women 47.5%, 205/432 (42.8%-52.2%) vs. men 52.6%, 227/432 (47.8%-57.2%); p = 0.31]. When limited to unique physician individuals, women were significantly outnumbered by men [40.1%, 71/177 (33.2%-47.5%) vs. 59.9%, 106/177 (52.5%-66.8%); p = 0.01]. This analysis demonstrated mixed findings, with more women across all positions overall but significantly more men when limited to unique physicians. Diversity in conference positions begets a broader array of perspectives, knowledge, and expertise, and can aid in realizing greater diversity in related areas. Thus, academic conference diversity should be prioritized and thoughtfully pursued.
    Keywords:  academic medicine; apheresis; conference speakers; diversity; equity; inclusion; transfusion medicine
    DOI:  https://doi.org/10.1002/jca.70015
  75. Nature. 2025 Mar 07.
    How a PhD student's lab size affects their chance of future academic success.
    Humberto Basilio.
      
    Keywords:  Careers; Publishing; Research management; Scientific community
    DOI:  https://doi.org/10.1038/d41586-025-00644-9
  76. J Am Acad Dermatol. 2025 Mar 12. pii: S0190-9622(25)00431-1. [Epub ahead of print]
    Differences in NIH Funding, Publications, and H-Index between Men and Women Who Are Endowed Dermatology Chairs.
    Ferdos Abdulkader, Sana Khan, Claire Reynolds, Ramiro Rodriguez, Ani Oganesyan, Robert P Dellavalle.
      
    DOI:  https://doi.org/10.1016/j.jaad.2025.03.013
  77. Nature. 2025 Mar 07.
    AI tools are spotting errors in research papers: inside a growing movement.
    Elizabeth Gibney.
      
    Keywords:  Machine learning; Software; Technology
    DOI:  https://doi.org/10.1038/d41586-025-00648-5
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