bims-evares Biomed News
on Evaluation of research
Issue of 2025–03–02
85 papers selected by
Thomas Krichel, Open Library Society
  1. Research trends in glioma chemoradiotherapy resistance: a bibliometric analysis (2003-2023).
  2. Correlation between gut microbiota and tumor immune microenvironment: A bibliometric and visualized study.
  3. Bibliometric analysis of targeted immunotherapy for osteosarcoma-current knowledge, hotspots and future perspectives.
  4. Representation of Women Authors in the 100 Most-Cited Facial Plastic and Reconstructive Surgery Articles.
  5. Frontiers of premature ovarian insufficiency research: an analysis from the top 100 most influential articles in the field.
  6. Bibliometric analysis of additive manufacturing in cranial and craniofacial implant research.
  7. The Clinical Research Landscape of Intracranial Nicardipine for Aneurysmal Subarachnoid Hemorrhage: Insights From Bibliometric Analysis.
  8. Decoding breast cancer imaging trends: the role of AI and radiomics through bibliometric insights.
  9. Research trends and hotspots evolution of artificial intelligence for cholangiocarcinoma over the past 10 years: a bibliometric analysis.
  10. A bibliometric analysis of metonymy in SSCI-indexed research (2000-2023): retrospect and prospect.
  11. Bibliometric Analysis of Alpha-Synuclein Determination by Biopsy in Peripheral Tissues of Patients With Parkinson's Disease.
  12. Bibliometric analysis of research on manual therapy for low back pain from 2013 to 2023.
  13. Bibliometric Analysis of Single-Atom Catalysis: A Scoping Review.
  14. Bibliometric analysis of research on spinal cord injury and Mesenchymal stem cell: Trends and frontiers.
  15. Global research trends of immunosenescence and immunotherapy: A bibliometric study.
  16. Research hotspots and trends of immunotherapy and melanoma: A bibliometric analysis during 2014-2024.
  17. Inclusive Dentistry? Mapping the Landscape of Autism and Dentistry Research through Bibliometric Analysis.
  18. Trends and Insights in Direct Anterior Total Hip Arthroplasty: A Comprehensive Bibliometric Analysis.
  19. Tracing the Blockchain Challenges in Healthcare: A Topic Modeling and Bibliometric Analysis.
  20. Hotspots and Trends in Spinal Cord Stimulation Research for Spinal Cord Injury: A Bibliometric Analysis with Emphasis on Motor Function Recovery (2014-2024).
  21. Frontiers and Hotspot Evolution of NLRP3 Inflammasome in Myocardial Infarction Research: A Bibliometric Analysis From 2013 to 2024.
  22. Trend of Suicide Research in South Asia: A Bibliometric Analysis of the Last Three Decades.
  23. An analysis of the top 500 anesthesiology publications with the highest altmetric attention scores.
  24. Research trends on stereotactic radiosurgery in brain metastases: a bibliometric analysis from 2013 to 2023.
  25. Recent advances in green deep eutectic solvents for lithium-ion battery recycling: A perspective on bibliometric analysis.
  26. Trends and Hotspots in Nanomedicine Applications for Pain: A Bibliometric Analysis from 1999 to 2024.
  27. Data governance and open sharing in the fields of life sciences and medicine: A bibliometric analysis.
  28. Global research progress in antibody-drug conjugates for solid tumors: Bibliometrics and visualized analysis.
  29. Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study.
  30. Bibliometric insight into neoadjuvant immunotherapy in non-small cell lung cancer: trends, collaborations, and future avenues.
  31. Bibliometric Analysis of Dual Mobility Total Hip Arthroplasty.
  32. The evolution of green finance research: A comprehensive bibliometric analysis.
  33. Bibliometric insights into systemic sclerosis with renal involvement: trends, contributions, and future directions.
  34. Knowledge Domain and Emerging Trends in the Treatment of Patients with Chronic Obstructive Pulmonary Disease Combined with Respiratory Failure: A Scientometric Review Based on CiteSpace Analysis.
  35. A 10-year bibliometric analysis in the field of osteosarcoma treatment from 2014 to 2023.
  36. A bibliometric analysis on delirium in intensive care unit from 2013-2023.
  37. Current Status and Future Directions of Ferroptosis Research in Breast Cancer: Bibliometric Analysis.
  38. Silent battles, global insights: anxiety and depression in the world of assisted reproduction.
  39. Application trends and research hotspots of endoscopic enucleation of the prostate: a bibliometric and visualization analysis.
  40. Global hotspots and research frontiers of Moyamoya disease and radiological features: A bibliometric analysis.
  41. I do not think before I leap (buy)! Impulse buying: An integrative review and future research directions.
  42. Efferocytosis and inflammation: a bibliometric and systematic analysis.
  43. Bibliometric analyses of climate psychology: critical psychology and climate justice perspectives.
  44. Trends in Interventional Radiology: A Bibliometric Analysis of the Canadian Association of Radiologists Journal.
  45. Artificial intelligence in otorhinolaryngology: current trends and application areas.
  46. Global research trends on the associations between chronic kidney disease and mitochondria: insights from the bibliometric analysis.
  47. The role of glial cells in neuralgia: a bibliometric exploration.
  48. Research on neglected tropical diseases in Haiti: a scientometrics analysis, 1923-2022.
  49. Characteristics of highly cited articles in cerebral angiography.
  50. Profile of STING agonist and inhibitor research: a bibliometric analysis.
  51. The role of artificial intelligence in aortic valve stenosis: a bibliometric analysis.
  52. Evaluation of New Zealand's Radiology, Nuclear Medicine, and Medical Imaging Research Output: A Bibliometric-Based Approach.
  53. AI-Augmented Psychosocial Interventions: A Bibliometric Review and Implications for Nursing.
  54. Mapping the landscape of gastric signet ring cell carcinoma: Overcoming hurdles and charting new paths for advancement.
  55. Edible Insects: Global Research Trends, Biosafety Challenges, and Market Insights in the Mexican Context.
  56. Factors for predicting time to acceptance in the journal of the American academy of orthopaedic surgeons.
  57. Trends in Clinical Cardiac Photon-Counting Detector CT Research: A Comprehensive Bibliometric Analysis.
  58. Angiogenesis after acute myocardial infarction: a bibliometric -based literature review.
  59. The 50 most cited studies on trochleoplasty.
  60. Artificial Intelligence Research Receives Similar Online Attention but Increased Citation Rates Compared to Control Articles.
  61. [Research progress and frontier analysis of Laugier-Hunziker syndrome at home and abroad based on Citespace].
  62. The link between hyperuricemia and diabetes: insights from a quantitative analysis of scientific literature.
  63. Half-Century Scientometric Analysis: Unveiling the Excellence of Fungi as Biocontrol Agents and Biofertilisers.
  64. Trends and Gaps in Colorectal Cancer Screening Research in the Arab World: A 16-Year Bibliometric Analysis (2007-2023).
  65. Bibliometric study of publications on pancreatic surgery carried out by spanish surgeons.
  66. HIV and the gut microbiome: future research hotspots and trends.
  67. Unveiling causal relationships between tobacco use phenotypes and neuroimaging: Insights from bidirectional Mendelian randomization and bibliometric analysis.
  68. Quantitative and Qualitative Analysis of Clinical Trial Acronyms From Surgical Journals.
  69. From text to insight: A natural language processing-based analysis of burst and research trends in HER2-low breast cancer patients.
  70. The editorial boards of behavior-analytic journals: An analysis of geographic distribution and presumed gender.
  71. Global Perspectives on Obesity and Being Overweight: A Bibliometric Analysis in Relation to Sustainable Development Goals.
  72. Self-citation pattern among world's top 2 % of the scientists.
  73. Comment on 'the relationship between kidney disease and mitochondria: a bibliometric study'.
  74. A worldwide itinerary of research ethics in science for a better social responsibility and justice: a bibliometric analysis and review.
  75. A snapshot of female representation in the presentation of orthopaedic research, an Australian perspective.
  76. Examining the frequency of artificial intelligence generated content in anesthesiology and intensive care journal publications: A cross sectional study.
  77. Factors Associated With Gender Distribution in Academic Rhinology.
  78. Gender Differences in the Authorship of Gastroenterology Clinical Practice Guidelines.
  79. Psychological safety and psychosocial safety climate in workplace: A bibliometric analysis and systematic review towards a research agenda.
  80. Recent Advancements and Trends in Postharvest Application of Edible Coatings on Bananas: A Comprehensive Review.
  81. The Impact of Social Media for Hand Surgeons: A Prevalence and Correlation Study With Online and Academic Reputations.
  82. Gender diversity in endodontics: Women's representation at recent biennial meetings.
  83. Integrating narrative and bibliometric approaches to examine factors and impacts of tuberculosis treatment non-compliance.
  84. Advances in Huntington's Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review.
  85. The role of climatic changes in the emergence and re-emergence of infectious diseases: bibliometric analysis and literature-supported studies on zoonoses.
  1. Front Oncol. 2025 ;15 1539937
    Research trends in glioma chemoradiotherapy resistance: a bibliometric analysis (2003-2023).
    Shishi Yu, Jinya Wu, Yuan Jing, Ping Lin, Lang Lang, Yifan Xiong, Wangzhong Chen, Wenhua Liu, Changpeng Sun, Yuntao Lu.
       Background: Glioma is the most aggressive primary malignant tumor of the central nervous system, characterized by high recurrence rates and resistance to chemoradiotherapy, making therapeutic resistance a major challenge in neuro-oncology. Recent research emphasizes the role of the tumor microenvironment (TME) and immune modulation in glioma progression and resistance. Despite these advances, a comprehensive bibliometric analysis of research trends in glioma chemoradiotherapy resistance over the past two decades is lacking. This study aims to systematically evaluate the research landscape, identify emerging hotspots, and provide guidance for future investigations.
    Methods: Articles on glioma chemoradiotherapy resistance published between 2003 and 2023 were retrieved from the Web of Science Core Collection, resulting in 4,528 publications. Bibliometric tools, including VOSviewer, CiteSpace, and R packages such as bibliometrix and ggplot2, were used to analyze co-authorship networks, keyword evolution, and citation bursts to identify collaboration patterns, thematic developments, and influential contributions.
    Results: Publication output increased significantly between 2013 and 2022, peaking at 650 articles in 2022. Over 1,000 institutions from 88 countries contributed to this research. The United States, Switzerland, and Germany showed the highest citation impact, while China led in publication volume but demonstrated relatively lower citation influence. The research focus has shifted from traditional topics such as the "MGMT gene" to emerging areas including the "tumor microenvironment," "immune infiltration," and "nanoparticles." The androgen receptor was identified as a promising but underexplored therapeutic target.
    Conclusions: Research on glioma chemoradiotherapy resistance has seen substantial growth, with increasing emphasis on immune modulation, the tumor microenvironment, and novel therapeutic targets such as the androgen receptor. This study represents the first comprehensive bibliometric analysis of this field, providing a detailed overview of research trends and potential directions for future studies. The findings highlight the need for strengthened international collaboration and multidisciplinary approaches to address the challenges of therapeutic resistance in glioma.
    Keywords:  androgen receptor; bibliometric analysis; chemoradiotherapy resistance; glioma; immune infiltration; tumor microenvironment
    DOI:  https://doi.org/10.3389/fonc.2025.1539937
  2. World J Clin Oncol. 2025 Feb 24. 16(2): 101611
    Correlation between gut microbiota and tumor immune microenvironment: A bibliometric and visualized study.
    Zheng-Jun Hu, Hui-Rong Zhu, Yong-Jie Jin, Pan Liu, Xiao-Wei Yu, Yu-Ren Zhang.
       BACKGROUND: In recent years, numerous reports have been published regarding the relationship between the gut microbiota and the tumor immune microenvironment (TIME). However, to date, no systematic study has been conducted on the relationship between gut microbiota and the TIME using bibliometric methods.
    AIM: To describe the current global research status on the correlation between gut microbiota and the TIME, and to identify the most influential countries, research institutions, researchers, and research hotspots related to this topic.
    METHODS: We searched for all literature related to gut microbiota and TIME published from January 1, 2014, to May 28, 2024, in the Web of Science Core Collection database. We then conducted a bibliometric analysis and created visual maps of the published literature on countries, institutions, authors, keywords, references, etc., using CiteSpace (6.2R6), VOSviewer (1.6.20), and bibliometrics (based on R 4.3.2).
    RESULTS: In total, 491 documents were included, with a rapid increase in the number of publications starting in 2019. The country with the highest number of publications was China, followed by the United States. Germany has the highest number of citations in literature. From a centrality perspective, the United States has the highest influence in this field. The institutions with the highest number of publications were Shanghai Jiao Tong University and Zhejiang University. However, the institution with the most citations was the United States National Cancer Institute. Among authors, Professor Giorgio Trinchieri from the National Institutes of Health has the most local impact in this field. The most cited author was Fan XZ. The results of journal publications showed that the top three journals with the highest number of published papers were Frontiers in Immunology, Cancers, and Frontiers in Oncology. The three most frequently used keywords were gut microbiota, tumor microenvironment, and immunotherapy.
    CONCLUSION: This study systematically elaborates on the research progress related to gut microbiota and TIME over the past decade. Research results indicate that the number of publications has rapidly increased since 2019, with research hotspots including "gut microbiota", "tumor microenvironment" and "immunotherapy". Exploring the effects of specific gut microbiota or derived metabolites on the behavior of immune cells in the TIME, regulating the secretion of immune molecules, and influencing immunotherapy are research hotspots and future research directions.
    Keywords:  Bibliometric; CiteSpace; Gut microbiota; R-bibliometrics; Tumor immune microenvironment; VOSviewer
    DOI:  https://doi.org/10.5306/wjco.v16.i2.101611
  3. Front Immunol. 2024 ;15 1485053
    Bibliometric analysis of targeted immunotherapy for osteosarcoma-current knowledge, hotspots and future perspectives.
    Yunxiang Hu, Rui Yang, Shuai Ni, Zefeng Song.
       Objective: The objective of this study is to conduct a bibliometric analysis on examining the current condition, areas of interest, and rising trends of immunotherapy for osteosarcoma (ITFOS), as well as its importance in associated research domains.
    Methods: An extensive collection of academic papers on the use of ITFOS was obtained from the Web of Science between January 1, 2000 and October 20, 2023. Then, using a variety of tools like HisCite, VOSviewer, CiteSpace, and the bibliometrix package, a bibliometric study was carried out. This study included the collection of information on country, institution, author, journal, and keywords.
    Results: A comprehensive analysis was undertaken on a total of 616 publications obtained from 247 journals, encompassing the contributions of 3725 authors affiliated with 831 institutes spanning across 43 countries/regions. Notably, China exhibited the highest quantity of published 277 (44.99%) articles on ITFOS. The most productive institution was Zhejiang University, with 26 (4.22%) publications. The author with the highest publication output was Tsukahara, Tomohide from Japan with 15 (2.44%) publications. The article with the most citation was "DOI: 10.1200/JCO.2014.58.0225". Frontiers in Immunology demonstrated the highest level of productivity, having published a total of 31 (5.03%) articles. The most frequently used were "osteosarcoma," "immunotherapy," and "cancer,". Meanwhile, "sequencing", "prognostic signature" and "immune microenvironment" have been identified as the research frontiers for the forthcoming years.
    Conclusion: This paper provides a thorough evaluation of current research trends and advancements in ITFOS. It includes relevant research findings and emphasizes collaborative efforts among authors, institutions, and countries.
    Keywords:  immune checkpoint inhibitor; immune function; immunotherapy; osteosarcoma; targeted therapy
    DOI:  https://doi.org/10.3389/fimmu.2024.1485053
  4. Otolaryngol Head Neck Surg. 2025 Feb 25.
    Representation of Women Authors in the 100 Most-Cited Facial Plastic and Reconstructive Surgery Articles.
    Lindsay Fleischer, Yoo Jin Ahn, Matthew J Urban, Peter C Revenaugh, Ryan M Smith, Michael Eggerstedt.
       OBJECTIVE: This study aims to determine the representation of women among most-cited facial plastic and reconstructive surgery articles.
    STUDY DESIGN: A bibliometric analysis of the most-cited articles from 9 high-impact facial plastic surgery journals.
    SETTING: Online database.
    METHODS: A retrospective analysis of the 100 most-cited articles in facial plastic surgery was conducted using the Elsevier Scopus database. The representation of women among first, senior, and corresponding authors was assessed using the US Social Security Baby Names Database. Accredited websites were utilized for further clarification of gender, professional background, and title. A 2-tailed t-test was performed to compare the average number of citations by gender, while chi-square analysis was used to compare the relative number of women authors between 5-year intervals, citation rank, and nationalities. A significance level of 0.05 was used.
    RESULTS: The top 100 most-cited articles had the highest total number of citations between 2000 and 2004. US institutions published 71% of these articles. The gender of 99% of first authors, 94% of senior authors, and 94% of corresponding authors was identified. Among these, 11% of first authors, 14% of senior authors, and 10% of corresponding authors were women. Of the 19 women authors, 11 were physicians. No statistically significant difference in the relative number of first, senior, and corresponding women authors was observed between years of publication, citation quartile, and article nationality.
    CONCLUSION: Despite increasing women facial plastic surgery trainees, women's academic contributions continue to trail. Additional efforts are needed to support and highlight academic achievements of women facial plastic surgeons.
    Keywords:  gender bias; journal impact factor; otolaryngology/statistics and numerical data; physicians; women; women/statistics and numerical data
    DOI:  https://doi.org/10.1002/ohn.1177
  5. Gynecol Endocrinol. 2025 Dec;41(1): 2470986
    Frontiers of premature ovarian insufficiency research: an analysis from the top 100 most influential articles in the field.
    Cheng Cheng, Suhua Liu, Ziqing Yu, Kexuan Zhu, Rui Liu, Xuhao Li, Jing Zhang.
      Objectives: Premature ovarian insufficiency (POI) is a serious condition that affects women worldwide, In recent years, the number of research publications on POI has increased over the last decades because of the advancement of cutting-edge research in gynecology and the deepening of disciplinary interactions. At the same time, there is a more urgent need to systematically analyze and review existing studies to generalize the research paradigm and disciplinary structure of the field under technological changes.
    Materials and methods: We selected the top 100 most cited papers in the Web of Science (WOS) SCI-Expanded database. Knowledge graphs were constructed through the VOS viewer, Cite Space, and Scimago Graphica software, and then relevant information retrieved from the literature was edited using Excel to assess research priorities and trends in the field.
    Results: A total of 53 periodicals from 34 different nations and regions published the 100 most-cited publications between 1999 and 2024. The Journal of Clinical Endocrinology & Metabolism published the majority of the papers, while The Lancet had the highest average number of citations per piece. The United States of America produced the highest contribution in terms of publications, with China and France closely trailing after. In terms of total publications, Erasmus MC, Shanghai Jiao Tong University, and Shandong University each contributed the highest number of papers. The main categories were obstetrics and gynecology, endocrinology and metabolism, and reproductive biology. The top five keywords were: failure, women, ANTI-MULLERIAN HORMONE, NATURAL MENOPAUSE, and AGE. The study of HERITAGE AND GENETICS, CARDIOVASCULAR DISEASES, and CELL BIOLOGY AND IMMUNOGENETICS is becoming more and more popular in POI, as shown by cluster analysis.
    Conclusions: Bibliometric analysis enables POI researchers to efficiently and visibly pinpoint the cutting-edge areas and focal points of their study. Potential topics of future study may include genetic and molecular biological pathways, cardiovascular pathology, and immunology.
    Keywords:  Bibliometric analysis; CiteSpace; Scimago graphica; VOSviewer; citations; primary ovarian insufficiency; trends
    DOI:  https://doi.org/10.1080/09513590.2025.2470986
  6. J Craniomaxillofac Surg. 2025 Feb 22. pii: S1010-5182(25)00071-X. [Epub ahead of print]
    Bibliometric analysis of additive manufacturing in cranial and craniofacial implant research.
    Bengi Yilmaz Erdemli, Simel Ayyıldız.
      Additive manufacturing (AM) offers solutions to complex surgical challenges by enabling the production of medical devices with highly sophisticated and customized designs. As a result, it has significantly advanced the field of implant customization for cranial and craniofacial reconstruction. However, comprehensive insights into the research trends in this area remain limited. This study aims to provide a bibliometric analysis of literature related to AM in cranial and craniofacial implant applications from the Web of Science (WoS) Core Collection. A highly refined search strategy was employed by utilizing an advanced query with specific keywords such as 'additive manufacturing,' 'cranial implants,' '3D printing,' and 'customized'. This search resulted in a total of 408 publications, which were then narrowed down to 331 articles by selection of articles as the publication type. A visualization tool named VOSviewer was employed to analyze trends in publication volume, author collaboration, journal impact, and keyword co-occurrence. The analysis revealed an increasing trend in research publications with a focus on patient-specific implants, 3D bioprinting technologies, and virtual surgical planning. Additionally, the collaborations between institutions in North America, Europe, and Asia are driving the field forward. Despite significant progress since 2000s, there are still challenges related to material optimization, regulatory concerns, and clinical integration.
    Keywords:  3D printing; Additive manufacturing; Bibliometric analysis; Cranial implants; Customized
    DOI:  https://doi.org/10.1016/j.jcms.2025.02.018
  7. Drug Des Devel Ther. 2025 ;19 1129-1146
    The Clinical Research Landscape of Intracranial Nicardipine for Aneurysmal Subarachnoid Hemorrhage: Insights From Bibliometric Analysis.
    Guangtang Chen, Yi Cao, Xiaolin Du, Junshuan Cui, Xi Zeng, Hua Yang, Zeguang Ren, Kaya Xu.
       Background: The 2023 American Heart Association/American Stroke Association guideline and Wessels et al's 2024 randomized controlled trial highlight the potential benefits of intracranial nicardipine for aneurysmal subarachnoid hemorrhage (aSAH). This study aims to systematically identify the publication trends and research hotspots in this field through bibliometric analysis.
    Methods: Relevant publications were sourced from the Web of Science Core Collection (WoSCC). Bibliometric and visualization analyses were conducted using the online tools of the WoSCC database and CiteSpace 6.2.R6.
    Results: Analysis of 28 articles published by 158 researchers from 55 institutions across 8 countries revealed an intermittent small-scale growth in annual publication volume from 1994 to 2024, with a continuous rise in annual citation volume since 2005, indicating growing interest in the field. Japan, Germany, and the United States of America (USA) were the most prolific and influential countries. Institutions such as Tokyo Women's Medical University showed particularly significant contributions. Kasuya Hidetoshi was the most prolific author. There was little global collaboration among countries, institutions, and authors, with distinct regional research characteristics: Japan and Germany focused on intracranial implants, while the USA concentrated on intrathecal injections. Major publishing and co-cited journals included Neurocritical Care, Acta Neurochirurgica, Journal of Neurosurgery, and Stroke. Popular keywords in 2024 included "preventing cerebral vasospasm", "delayed cerebral ischemia", "outcome events", and "clinical trials", revealing current research hotspots.
    Conclusion: This study maps the global clinical research landscape of intracranial application of nicardipine for aSAH from 1994 to 2024, providing valuable references and guidance for future research.
    Keywords:  NPRI; aneurysm subarachnoid hemorrhage; intrathecal; intraventricular; nicardipine
    DOI:  https://doi.org/10.2147/DDDT.S503226
  8. Breast Cancer Res. 2025 Feb 25. 27(1): 29
    Decoding breast cancer imaging trends: the role of AI and radiomics through bibliometric insights.
    Xinyu Wu, Yufei Xia, Xinjing Lou, Keling Huang, Linyu Wu, Chen Gao.
       BACKGROUND: Radiomics and AI have been widely used in breast cancer imaging, but a comprehensive systematic analysis is lacking. Therefore, this study aims to conduct a bibliometrics analysis in this field to discuss its research status and frontier hotspots and provide a reference for subsequent research.
    METHODS: Publications related to AI, radiomics, and breast cancer imaging were searched in the Web of Science Core Collection. CiteSpace plotted the relevant co-occurrence network according to authors and keywords. VOSviewer and Pajek were used to draw relevant co-occurrence maps according to country and institution. In addition, R was used to conduct bibliometric analysis of relevant authors, countries/regions, journals, keywords, and annual publications and citations based on the collected information.
    RESULTS: A total of 2,701 Web of Science Core Collection publications were retrieved, including 2,486 articles (92.04%) and 215 reviews (7.96%). The number of publications increased rapidly after 2018. The United States of America (n = 17,762) leads in citations, while China (n = 902) leads in the number of publications. Sun Yat-sen University (n = 75) had the largest number of publications. Bin Zheng (n = 28) was the most published author. Nico Karssemeijer (n = 72.1429) was the author with the highest average citations. "Frontiers in Oncology" was the journal with the most publications, and "Radiology" had the highest IF. The keywords with the most frequent occurrence were "breast cancer", "deep learning", and "classification". The topic trends in recent years were "explainable AI", "neoadjuvant chemotherapy", and "lymphovascular invasion".
    CONCLUSION: The application of radiomics and AI in breast cancer imaging has received extensive attention. Future research hotspots may mainly focus on the progress of explainable AI in the technical field and the prediction of lymphovascular invasion and neoadjuvant chemotherapy efficacy in clinical application.
    Keywords:  Artificial intelligence; Breast neoplasms; Medical imaging; Radiomics
    DOI:  https://doi.org/10.1186/s13058-025-01983-1
  9. Front Oncol. 2024 ;14 1454411
    Research trends and hotspots evolution of artificial intelligence for cholangiocarcinoma over the past 10 years: a bibliometric analysis.
    Ke-Xie Wang, Yu-Ting Li, Sun-Hu Yang, Feng Li.
       Objective: To analyze the research hotspots and potential of Artificial Intelligence (AI) in cholangiocarcinoma (CCA) through visualization.
    Methods: A comprehensive search of publications on the application of AI in CCA from January 1, 2014, to December 31, 2023, within the Web of Science Core Collection, was conducted, and citation information was extracted. CiteSpace 6.2.R6 was used for the visualization analysis of citation information.
    Results: A total of 736 publications were included in this study. Early research primarily focused on traditional treatment methods and care strategies for CCA, but since 2019, there has been a significant shift towards the development and optimization of AI algorithms and their application in early cancer diagnosis and treatment decision-making. China emerged as the country with the highest volume of publications, while Khon Kaen University in Thailand was the academic institution with the highest number of publications. A core group of authors involved in a dense network of international collaboration was identified. HEPATOLOGY was found to be the most influential journal in the field. The disciplinary development pattern in this domain exhibits the characteristic of multiple disciplines intersecting and integrating.
    Conclusion: The current research hotspots primarily revolve around three directions: AI in the diagnosis and classification of CCA, AI in the preoperative assessment of cancer metastasis risk in CCA, and AI in the prediction of postoperative recurrence in CCA. The complementarity and interdependence among different AI applications will facilitate future applications of AI in the CCA field.
    Keywords:  artificial intelligence; bibliometrics; cholangiocarcinoma; convolutional neural networks; deep learning
    DOI:  https://doi.org/10.3389/fonc.2024.1454411
  10. Front Psychol. 2025 ;16 1499563
    A bibliometric analysis of metonymy in SSCI-indexed research (2000-2023): retrospect and prospect.
    Yi Sun, Mocheng Lin.
       Introduction: Metonymy has gained increasing attention for its role in shaping language, thought, and communication. Despite its prominence, the thematic evolution and future directions of metonymy research remain underexplored. This study seeks to address this gap by analyzing metonymy research published between 2000 and 2023, providing a comprehensive overview of its key trends and emerging themes.
    Methods: A bibliometric analysis was conducted using data sourced from the Social Science Citation Index (SSCI) within the Web of Science Core Collection. Co-citation and co-word analysis were employed alongside k-means clustering techniques to identify research themes. Predictive modeling, including ARIMA and LSTM approaches, was used to forecast future research topics based on keyword trends.
    Results: The analysis identified 11 key research clusters, highlighting the central role of cognitive and conceptual linguistics in metonymy research, along with its applications in semantics, pragmatics, and multimodal contexts. Predictive modeling suggested the emergence of seven new research themes for 2024-2028, including the interaction between metonymy and discourse, its role in multimodal communication, and its application in social and cultural narratives.
    Discussion: This study underscores the interdisciplinary nature of metonymy research, bridging linguistic, cognitive, and social dimensions. The findings highlight promising areas for future exploration, namely, its integration into digital communication and its impact on cultural identity construction. The methodological approach offers a robust framework for analyzing and predicting research trends, paving the way for innovative contributions to the field.
    Keywords:  Python; bibliometric analysis; figurative language; metaphor; metonymy
    DOI:  https://doi.org/10.3389/fpsyg.2025.1499563
  11. Int J Telemed Appl. 2025 ;2025 6469893
    Bibliometric Analysis of Alpha-Synuclein Determination by Biopsy in Peripheral Tissues of Patients With Parkinson's Disease.
    Aigerim B Utegenova, Aigul P Yermagambetova, Gulnar B Kabdrakhmanova, Alima A Khamidulla, Zhanylsyn U Urasheva, Nazym K Kenzhinа, Zhanna Zhussupova, Gulzhanat N Nurlanova.
      Study Evaluation: The bibliometric analysis of the published results of the alpha-synuclein (α-syn) detection study in the peripheral tissues of patients with Parkinson's disease was carried out by us to study scientific activity and scientific productivity, to measure the quantitative and qualitative characteristics of scientific publications, author productivity, and citation of works, as well as the degree of interrelation between authors, journals, institutes, and countries. Purpose: This study is aimed at bibliometrically analyzing the results of studies on the detection of α-syn in peripheral tissue biopsy of patients with Parkinson's disease from 2013 to 2023. Methods: The data was extracted from the Scopus database collection using an inclusive search strategy. Performance analysis and science mapping were conducted using RStudio v.4.3.1 with the bibliometrix R-package. The analyzed data encompassed trends in publication and citation and the identification of leading institutions, primary sources, authors, and collaborative countries. Results: A total of 124 relevant studies from 53 different sources were thoroughly analyzed. The analysis included the materials of 843 authors, which together gave an impressive average of 37.67 citations per document over the past decade. The annual growth rate in this area of research, according to calculations, was 10.84%, indicating a steady increase in the number of publications over the study period. The huge volume of research results is highlighted by the inclusion of 231 unique keywords of authors. Conclusion: Studies on the detection of pathological α-syn in peripheral tissues for early morphological verification of the diagnosis of Parkinson's disease are relevant in clinical neurology. α-syn detected in the skin biopsy of patients on the basis of this study and data from the world literature meets the requirements for biomarkers.
    Keywords:  Parkinson's disease; alpha-synuclein; bibliometric analysis; biopsy
    DOI:  https://doi.org/10.1155/ijta/6469893
  12. Medicine (Baltimore). 2025 Feb 21. 104(8): e41618
    Bibliometric analysis of research on manual therapy for low back pain from 2013 to 2023.
    Yi Guo, Zhichao Gong, Xiaowei Liu, Kun Ai, Wu Li, Jiangshan Li.
       BACKGROUND: Low back pain (LBP) is one of the most common symptoms prompting patients to seek treatment. Manual therapy is widely used to treat LBP. Nevertheless, there is a scarcity of bibliometric analyses examining the worldwide utilization of manual therapy for the treatment of LBP.
    METHODS: This research used the Online Bibliometric overview Platform website (https://bibliometric.com), CiteSpace (6.2.R4), and VOSviewer (1.6.19) to provide a comprehensive analysis of the current status and prospective developments in the field. The Web of Science Core Collection (WOSCC) database was searched for publications from August 1, 2013, to August 1, 2023 on manual therapy of low back pain.
    RESULTS: Among the identified articles, 488 fit the criteria. The number of papers on manual therapy for LBP has progressively risen over in the past 10 years, whereas the average number of citations of these papers has decreased. The leading countries producing publications on this discipline were the USA, Canada, and China. There were 345 authors of the studies, with Christine M. Goertz having the most publications. The University of Southern Denmark was the institution that contributed the most to the field. The Journal of Manipulative and Physiological Therapeutics published many of the research papers in this field. Keyword analysis showed that the relationship between low back pain, spinal manipulation, and management has been present throughout the development of this research area.
    CONCLUSIONS: Spinal manipulation, management, randomized controlled trials, Physical therapy, care and disability are the current research hotspots in the treatment of LBP with manual therapy. In addition, research on complementary medicine and clinical practice guidelines may become an important trend in the future.
    DOI:  https://doi.org/10.1097/MD.0000000000041618
  13. Recent Pat Nanotechnol. 2025 Feb 24.
    Bibliometric Analysis of Single-Atom Catalysis: A Scoping Review.
    Muffarih Shah, Noor Majeed, Asif Ali, Abdul Hameed, Touseef Rehan, Nasrullah Shah.
       BACKGROUND: Single-Atom Catalysts (SACs) are heterogeneous catalysts that demonstrate exceptional efficiency and selectivity due to the use of individual metal atoms at the atomic scale. The substantial number of patents filed on SACs underscore their commercial and technological importance, highlighting their potential across various industries. SACs are increasingly applied in areas such as energy generation, environmental applications, and chemical synthesis, reflecting their growing scientific and technical importance.
    OBJECTIVES: The objective of this study was to conduct a comprehensive evaluation of existing literature on SACs and the use of bibliometric analysis to identify scientific output and topic patterns of research on SACs.
    METHODS: A bibliometric analysis was performed on 488 papers related to SACs, utilizing the Web of Science database of data collection. Analysis of Co-occurrence of keywords, trending research topics, Citation analysis, Publication areas, the five-year record of Publications, and funding sources were examined using VOS viewer, R software, and Microsoft Excel.
    RESULTS: The analysis indicates a steady growth in publication on SACs in recent years, with China leading in research output followed closely by the USA. The highlighting of the global impact and the collaborative nature of SAC research. The study reveals a diverse range of applications and emphasizes the increasing scientific and technical focus on this subject.
    CONCLUSION: This study highlights the essential role of SACs in advancing catalytic science and maps key trends, collaborations, and applications within the field. The bibliometric insights provide valuable guidance for the researchers, pointing to potential applications in energy storage, environmental remediation, and sustainable chemical synthesis. Emerging challenges, such as stability, scalability, and the development of new materials, call for further investigation to unlock the full potential of SACs. These insights support future innovation and exploration in the expanding field of SAC research.
    Keywords:  Program R; Single atom catalysis; VOSviewer; bibliometric analysis; scientific output
    DOI:  https://doi.org/10.2174/0118722105347268250206063445
  14. World Neurosurg. 2025 Feb 24. pii: S1878-8750(25)00189-5. [Epub ahead of print] 123833
    Bibliometric analysis of research on spinal cord injury and Mesenchymal stem cell: Trends and frontiers.
    HongPeng Ma, Bo Yang, Yan Li, Cong Xing, Qi Zhang, Guangzhi Ning.
       BACKGROUND: Spinal cord injury (SCI) is a serious neurotraumatic condition leading to motor and sensory dysfunction. Despite advancements in treatment, a complete cure remains elusive. Mesenchymal stem cell (MSC) transplantation has become a popular research area for SCI repair, with numerous publications. However, the current research status and trends are unclear. This study aims to conduct a bibliometric analysis of MSC therapy for SCI to identify these trends.
    METHODS: Articles related to MSC therapy for SCI were searched in the Web of Science Core Collection. Data on publication year, country, journal, keywords, and citation frequency were analyzed using Bibliometrix and CiteSpace.
    RESULTS: A total of 1,765 articles were retrieved, showing an increasing trend in publications. "Neural Regeneration Research" had the most and fastest-growing number of publications, with 59 articles. Kocsis, Jeffery D was the most prolific author with 23 articles. China led with 775 publications. However, more collaboration among authors, institutions, and countries is needed. Current research focuses on cell differentiation, axon regeneration, and exosome extraction.
    CONCLUSION: This study offers a comprehensive overview of the current state and future directions of MSC therapy research for SCI, providing a foundation for further research and clinical applications.
    Keywords:  Bibliometric; Mesenchymal stem cell; Spinal cord injury
    DOI:  https://doi.org/10.1016/j.wneu.2025.123833
  15. Hum Vaccin Immunother. 2025 Dec;21(1): 2469403
    Global research trends of immunosenescence and immunotherapy: A bibliometric study.
    Wendi Li, Lin Xiao, Haiyang Li, Wei Cui.
      Immunosenescence refers to the gradual decline in immune system function with age, increasing susceptibility to infections and cancer in the elderly. The advent of novel immunotherapies has revolutionized the field of cancer treatment. However, the majority of patients exhibit poor re-sponses to immunotherapy, with immunosenescence likely playing a significant role. In recent years, significant progress has been made in understanding the interplay between immunosenescence and immunotherapy. Our research aims to explore the prospects and development trends in the field of immunosenescence and immunotherapy using a bibliometric analysis. Relevant articles were collected from the Web of Science Core Collection (WoSCC) (retrieved on July 20, 2024). Primary bibliometric characteristics were analyzed using the R package "Biblio-metrix," and keyword co-occurrence analysis and visualization were conducted using VOSviewer. A total of 213 English-language original research and review articles spanning 35 years were re-trieved for bibliometric analysis. There was a surge in publications in this field starting in 2017. The United States and China contributed the most articles. Frontiers in Immunology was the most productive journal, while the University of California System was the highest contributing institution. Besse Benjamin from France emerged as the most influential researcher in this field. Popular keywords included "nivolumab," "T cells," "dendritic cells," and "regulatory T cells." The "immunosenescence-associated secretory phenotype" has become a new hotspot, with immune checkpoint inhibitors remaining a central theme in this domain. The field of immunosenescence and immunotherapy is entering a phase of rapid development and will continue to hold significant value in future research.
    Keywords:  Immunosenescence; bibliometric analysis; cancer; immune checkpoint inhibitors; immunotherapy
    DOI:  https://doi.org/10.1080/21645515.2025.2469403
  16. Hum Vaccin Immunother. 2025 Dec;21(1): 2464379
    Research hotspots and trends of immunotherapy and melanoma: A bibliometric analysis during 2014-2024.
    Zixuan Jia, Youao Zhang, Luyan Cao, Jieyan Wang, Hui Liang.
      Over the last decade, the increasing global prevalence of melanoma has sparked growing interest in immunotherapies, which show significant potential against this form of skin cancer. This research aims to offer a framework to guide future studies and inspire new research directions. In this study, we used the Web of Science Core Collection to collect papers on immunotherapy and melanoma published between 2014 and 2024. With Excel and visualization tools like VOSviewer, COOC 13.2, Citespace, and Bibliometrix (R-Tool of R-Studio), we analyzed the data to spot trends and new focuses in the research. Our findings indicate a substantial surge in research activity concerning immunotherapy and melanoma between 2014 and 2024. The USA and China emerged as leading contributors, engaging in extensive and close collaborative efforts with European counterparts. Furthermore, seven of the top 10 research institutions are located in the USA, with the MD Anderson Cancer Center in Texas being the most productive. In addition, the Journal of Cancer Immunotherapy is the journal with the most articles published in the field. Professor Georgina V. Long from the Melanoma Institute at the University of Sydney was one of the most productive scholars. Keyword analysis shows that immune checkpoint inhibitors, tumor microenvironment and targeted therapies are key areas of interest for the research community. This paper uses bibliometric analysis to outline research trends and key points in immunotherapy and melanoma from 2014 to 2024, which helps understand the current research and guides future research directions.
    Keywords:  Melanoma; immune checkpoint inhibitors; immunotherapy; targeted therapy; tumor microenvironment
    DOI:  https://doi.org/10.1080/21645515.2025.2464379
  17. J Autism Dev Disord. 2025 Feb 28.
    Inclusive Dentistry? Mapping the Landscape of Autism and Dentistry Research through Bibliometric Analysis.
    Pedro Vitali Kammer, Bruna Borges de Souza, Juliana da Silva Moro, Paulo Antônio Martins-Júnior, Mariane Cardoso, Carla Miranda Santana, Michele Bolan.
      Conduct a bibliometric analysis of articles related to dentistry and autism. A search strategy was constructed and conducted at the Web of Science database. The following information was extracted from each paper: title, authorship, year of publication, title of the journal, study subject dental care, oral health status, dental behavior support), study design, and number of citations. A total of 2,637 articles were obtained from the WoS-CC search. After selection, 422 papers were included, published from 1996 to 2024, and had 6,728 citations. Observational studies constituted most publications (214 papers). Among the focus of published articles, "oral health status" emerged as the predominant subject followed by "dental behavior support". More than half of the included papers were published in the last five years, accounting for 70.6% of the total. There has been a notable increase in research publications on autism and dentistry over time, primarily comprising observational studies. The predominant themes revolved around oral health status and dental behavior support.
    Keywords:  Autism spectrum disorder; Bibliometrics; Dental care; Dentistry; Oral health
    DOI:  https://doi.org/10.1007/s10803-025-06748-5
  18. Hip Pelvis. 2025 Mar 01. 37(1): 53-63
    Trends and Insights in Direct Anterior Total Hip Arthroplasty: A Comprehensive Bibliometric Analysis.
    Ralph Chalhoub, Maroun Aoun, Fong H Nham, Eliana Kassis, Mohammad Daher, Mouhanad M El-Othmani.
       Purpose: Total hip arthroplasty (THA), a commonly performed surgical procedure for management of end-stage osteoarthritis, is considered minimally invasive and the popularity of the direct anterior approach (DAA) is increasing. The objective of this study is to analyze the current literature on DAA THA through conduct of a comprehensive bibliometric analysis.
    Materials and Methods: A comprehensive search of the Web of Science Core Collection was conducted for identification of articles published between 1993 and 2022. Specific keywords associated with hip replacement and the anterior approach were used as an attempt to identify articles published in scientific journals.
    Results: As a result of the analysis, 743 articles were linked to DAA THA. The highest number of annual publications was reported for 2021, with 120 articles, followed by 2022 with 113 articles, 2020 with 104 articles, and 2018 with 69 articles. The United States led in contributions with 34.1% in production. The Medical University of Innsbruck contributed the highest number of studies with 263 articles, followed by the University of Ottawa with 229. The Journal of Arthroplasty emerged as the most influential journal with 903 articles and 4,571 citations. Keywords including "dislocation," "posterior approach," and "revision" were used frequently in 2015-2020, along with the increasing emphasis on perioperative complications and comparing different approaches.
    Conclusion: The findings of this analysis provide helpful insights into the current attitude regarding DAA THA research, highlighting emerging trends and guiding the direction of future research. The increasing scientific production reflects growing interest in DAA THA.
    Keywords:  Arthroplasty; Bibliometrics; Hip; Hip prosthesis; Replacement
    DOI:  https://doi.org/10.5371/hp.2025.37.1.53
  19. Blockchain Healthc Today. 2024 ;7
    Tracing the Blockchain Challenges in Healthcare: A Topic Modeling and Bibliometric Analysis.
    Mohammad Mehraeen, Laya Mahmoudi.
      The application of blockchain technology to healthcare offers promise in providing solutions to some key challenges related to data sharing, privacy, security, and access control. However, several barriers prevent the widespread adoption of blockchain and prompted research efforts. This study aims to conduct a bibliometric analysis of 196 documents indexed in the Scopus database to examine their structure, impact, contributors, and journals. The bibliometric analysis provides information on the publication and citation structure, as well as the most productive authors, universities, countries, journals, and most cited studies. In addition, it identifies the most prevalent keywords and their co-occurrence patterns on blockchain challenges in healthcare. A topic modeling approach, using Latent Dirichlet Allocation (LDA), is also employed to reveal the latent topical structure of this literature. As a result of these findings, the research landscape in this area has been quantitatively analyzed, identifying six critical challenges regarding the use of blockchain in healthcare: data privacy/security, integration with smart devices, interoperability, scalability, governance, and cost.
    Keywords:  Latent Dirichlet Allocation; bibliometric analysis; blockchain application; healthcare; topic modeling
    DOI:  https://doi.org/10.30953/bhty.v7.335
  20. World Neurosurg. 2025 Feb 24. pii: S1878-8750(25)00188-3. [Epub ahead of print] 123832
    Hotspots and Trends in Spinal Cord Stimulation Research for Spinal Cord Injury: A Bibliometric Analysis with Emphasis on Motor Function Recovery (2014-2024).
    ZengQiang OuYang, Rui Yang, Yue Wang.
       BACKGROUND: Spinal cord stimulation (SCS) has emerged as a key therapeutic strategy for enhancing motor recovery in spinal cord injury (SCI). This study employs bibliometric analysis to explore research trends and hotspots in SCS for motor recovery, highlighting advances and emerging directions over the past decade.
    METHODS: This cross-sectional bibliometric study retrieved publications on SCS for motor recovery from the Web of Science Core Collection database (2014-2024). Key information, including annual publication trends, contributing countries, institutions, authors, journals, keywords, and highly cited references, was analyzed using CiteSpace and VOSviewer.
    RESULTS: A total of 1,033 publications were analyzed, demonstrating exponential growth in SCS research since 2014. The United States and Switzerland were identified as leading contributors, with prominent institutions such as the Swiss Federal Institute of Technology and the University of California System driving advancements. Key authors included Grégoire Courtine and Susan J. Harkema. Research themes have evolved through four phases: foundational studies on spinal cord mechanisms, exploration of neural circuits, application of electrical stimulation for motor recovery, and advancements in non-invasive therapies such as transcutaneous SCS. Highly cited journals, including Nature and Lancet, have published transformative studies, underscoring the field's clinical and academic significance.
    CONCLUSIONS: This bibliometric analysis provides a comprehensive overview of SCS research for motor recovery post-SCI over the past decade. Interdisciplinary collaboration and technological innovation have positioned SCS as a cornerstone of SCI rehabilitation. Future efforts should focus on optimizing approaches, leveraging advanced imaging and AI technologies, and broadening rehabilitation goals to improve outcomes for SCI patients.
    Keywords:  Bibliometric analysis; Brain-computer interfaces; Epidural electrical stimulation; Motor recovery; Spinal cord injury; Spinal cord stimulation; Transcutaneous stimulation
    DOI:  https://doi.org/10.1016/j.wneu.2025.123832
  21. Cardiovasc Ther. 2025 ;2025 5178894
    Frontiers and Hotspot Evolution of NLRP3 Inflammasome in Myocardial Infarction Research: A Bibliometric Analysis From 2013 to 2024.
    Jin-Wen Wu, Qi Lan, Ding-Shan Zhang, Yu-Hong Jian, Lin Yu, Rui Hao, Ping Liu, Gang Luo, Ming-Tai Chen, Meng-Nan Liu.
      The NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome plays an essential role in myocardial infarction (MI) development. Up to now, no bibliometric analyses of NLRP3 in MI have been performed. Publications related to NLRP3 in MI from 1 January 2013 to 20 August 2024 were extracted from the Web of Science Core Collection (WoSCC). HistCite Pro, CiteSpace, VOSviewer, Scimago Graphica, and bibliometric online analysis program were used for bibliometric analysis and visualization. The impact of publications was assessed using the total global citation score (TGCS). A total of 324 articles (284 articles and 40 reviews) were included. China has published the most in this field, followed by the United States. Harbin Medical University was the leading institution for research related to NLRP3 in MI. Professor Abbate A. from the United States has made significant achievements in this field. International Immunopharmacology was the most active journal and Journal of Cardiovascular Pharmacology was the most cited journal. This study systematically summarizes the research results of NLRP3 in MI over the past 12 years. NLRP3 in myocardial ischemia-reperfusion injury (MIRI) will become a hot research topic, and translational research on NLRP3 inhibitors in MIRI will benefit a greater number of patients.
    Keywords:  NLRP3; bibliometric analysis; myocardial infarction; myocardial ischemia–reperfusion injury
    DOI:  https://doi.org/10.1155/cdr/5178894
  22. Omega (Westport). 2025 Feb 25. 302228251323991
    Trend of Suicide Research in South Asia: A Bibliometric Analysis of the Last Three Decades.
    S M Yasir Arafat, Ravi Philip Rajkumar, Sujita Kumar Kar.
      We aimed to perform a bibliometric review on suicide in South Asia. We conducted a search in Scopus. Articles on suicide published in English language with affiliations of eight South Asian countries between 1991 and the search date were included. The search revealed that the number of articles on suicide has been increased both yearly and decade wise. More than two-thirds of the papers published in India with regional collaborations. SMY Arafat and M Eddleston (n = 83) were the leading authors, the National Institute of Mental Health and Neuro Sciences, Bengaluru has the highest number of research publications (n = 298), the Indian Journal of Forensic Medicine And Toxicology was the leading journal, and the Wellcome Trust was the leading funder across decades after 2000s. This bibilometric analysis revealed that India has the leading role in suicide research, which is commensurate with its higher suicide burden.
    Keywords:  South Asia; bibliometric analysis; low- and middle-income country; suicide research; trend
    DOI:  https://doi.org/10.1177/00302228251323991
  23. Medicine (Baltimore). 2025 Feb 21. 104(8): e41523
    An analysis of the top 500 anesthesiology publications with the highest altmetric attention scores.
    Dilek Ömür Arça, Başak Bayram, Nilay Boztaş, İsmail Erdemir, Murat Çetin, Gönül Sağiroğlu, Volkan Hanci.
      Altmetrics is a web-based measurement method that assesses the online dissemination and interactions of an article. We performed an altmetric analysis of 500 papers with the highest altmetric attention score (AAS) published in anesthesiology-related journals. Journals were identified from the Web of Science (WoS) Master Journal List by Clarivate using the category "Anesthesiology." The altmetric data were obtained from the Altmetric Explorer database. The first 500 publications with the highest AAS scores among these journals were identified and analyzed. Using Spearman correlation, no correlation was observed between the AAS and either WoS or Google Scholar citations (R = 0.188, P < .001 and R = 0.161, P < .001, respectively). There was a weak correlation between blog mentions and both WoS citations and Google Scholar citations (R = 0.263, P < .001 and (R = 0.241, P < .001). A very strong correlation was observed between the number of Mendeley readers and both WoS and Google Scholar citations (R = 0.889, P < .001 and R = 0.905, P < .001). A significant difference in AAS and WoS citations was observed based on publication topic (P = .036 and P = .005, respectively), with algology being the most common topic (n = 206, 41.2%). Although AAS did not significantly affect traditional scientific citations, the analysis of subgroup correlations revealed notable differences. Our results suggest that traditional scientific citations (WoS and Google Scholar citations) are strongly influenced by the number of Mendeley readers. Further research is needed to understand these dynamics in academic discourse.
    DOI:  https://doi.org/10.1097/MD.0000000000041523
  24. Quant Imaging Med Surg. 2025 Feb 01. 15(2): 1297-1311
    Research trends on stereotactic radiosurgery in brain metastases: a bibliometric analysis from 2013 to 2023.
    Yuxin Zhong, Yiren Wang, Li Zhang, Zhongjian Wen, Shuilan Bao, Shouying Chen, Youhua Wang, Ping Zhou, Jing Chen, Huaiwen Zhang, Haowen Pang.
       Background: Brain metastases (BM) are the most common type of intracranial tumor and the leading cause of mortality in patients with systemic cancer. In recent years, stereotactic radiosurgery (SRS) has been widely used in the radiotherapy of BM due to its advantages of high positional accuracy and highly conformal dose distributions. However, this area lacks a bibliometric analysis. This study aims to provide an overview of recent trends and key topics related to SRS for BM treatment over the past decade and to anticipate future directions through bibliometric methods.
    Methods: We conducted a search in the Web of Science for publications on SRS in BM treatment from 2013 to 2023. VOSviewer, CiteSpace, and the R package "bibliometrix" were utilized to perform a bibliometric and visual analysis of online publications in this field, focusing on countries/regions, institutions, authors, journals, and keywords.
    Results: A total of 2,085 articles were identified in this study, with a steady increase observed in annual publications. The United States (USA) was the most productive country and the core of international cooperation; Mayo Clinic was the institution with the most publications and citations; Journal of Neuro-Oncology published the most papers; the most published author was Sahgal A, and Brown PD was the most co-cited author. The latest high-frequency keywords were immunotherapy, survival, prognosis, recurrence, leptomeningeal metastases, and so on. Keyword cooccurrence was used for cluster analysis, resulting in 7 clusters that highlight the emerging frontiers of SRS in BM treatment.
    Conclusions: As medical imaging informatics technology continues to advance, research into SRS for BM treatment has become increasingly in-depth. The immunoadjuvant therapy, biological effective dose, and radionecrosis have emerged as hot topics in recent years. Future work is ongoing to develop and improve artificial intelligence (AI) tools to assist in SRS treatment planning, thus benefiting more BM patients.
    Keywords:  Stereotactic radiosurgery (SRS); bibliometric analysis; brain metastases (BM); cancer; radiotherapy (RT)
    DOI:  https://doi.org/10.21037/qims-24-1403
  25. J Environ Manage. 2025 Feb 25. pii: S0301-4797(25)00646-2. [Epub ahead of print]377 124670
    Recent advances in green deep eutectic solvents for lithium-ion battery recycling: A perspective on bibliometric analysis.
    Renyin Cui, Yuhui Ran, Datao Shu, Qing Huang, Qingbin Song, Haixiang Wang, Jianming Zhu, Wenyi Yuan.
      The rapid growth of electric vehicles worldwide has resulted in a significant increase in the demand for lithium-ion batteries (LIBs), thereby accelerating the development of the LIBs recycling industry. Currently, the predominant methods for recycling spent LIBs include pyrometallurgical, hydrometallurgical, and direct recycling techniques, each with its own advantages and disadvantages. To enhance the recycling efficiency of cathode metals from spent LIBs while promoting environmental sustainability, green deep eutectic solvents (DESs) have attracted scholarly interest. In this study, we conducted a bibliometric analysis of DESs to elucidate research progress from both quantitative and visual perspectives and to delineate the evolution of research hotspots. The published literature in the Science Citation Index Expanded (SCIE) database of the Web of Science Core Collection from 2014 to 2023 was analyzed, resulting in a total of 393 articles and reviews through the CiteSpace and VOSviewer tools. The results indicate a substantial increase in the number of relevant publications since 2019, with China leading in the volume of publications, followed by the United States, Australia, and India. As a subset of hydrometallurgy, DESs remain closely associated with the hotspots of hydrometallurgy and spent LIBs. Given that DESs are similar to hydrometallurgical technologies, their industrial application for leaching processes is feasible. However, challenges such as high viscosity, metal precipitation, and separation difficulties present significant obstacles. This research aims to enhance the understanding of the current state of DESs in the field of positive electrode metal recycling from spent LIBs and serves as a historical reference for future investigations.
    Keywords:  Bibliometric analysis; Deep eutectic solvents; Metal recycling; Spent lithium-ion batteries
    DOI:  https://doi.org/10.1016/j.jenvman.2025.124670
  26. ACS Omega. 2025 Feb 18. 10(6): 6147-6163
    Trends and Hotspots in Nanomedicine Applications for Pain: A Bibliometric Analysis from 1999 to 2024.
    Shuailei Wang, Yumiao He, Yuguang Huang.
      Background: Pain, especially chronic pain, is a leading cause of individuals seeking medical attention and presents a significant public health challenge due to its widespread prevalence and associated healthcare costs. Nanomedicine has shown considerable potential in pain management research. However, there is a lack of comprehensive bibliometric and trend analyses that explore the current status, research hotspots, and future directions of nanomedicine applications in pain. Methods: To fill this gap, we analyzed English language publications related to nanomedicine and pain from the Web of Science Core Collection, spanning the period from January 1, 1999, to May 24, 2024. The analysis focused on publication trends, contributions by countries/regions, institutions, journals, research categories, prominent authors, key references, and keywords. Results: A total of 2370 papers were included. China leads in the number of published papers (785, 33.12%) and hosts numerous high-output institutions and funding agencies, followed by the USA. The International Journal of Pharmaceutics emerged as the leading journal in terms of publication volume. A clear interdisciplinary platform has been established between nanomedicine and the field of pain. "Nanoparticles" and "drug delivery" were identified as high-frequency keywords. The drug delivery systems for pain treatment were considered the main research hotspots, particularly for chronic pain. The keyword citation bursts indicate that the pain of biomarker monitoring is a future trend. Conclusions: The application of nanomedicine in pain has advanced rapidly. Increased funding and international collaboration are necessary with future potential to expand from pain treatment to monitoring and diagnosis.
    DOI:  https://doi.org/10.1021/acsomega.4c10893
  27. Digit Health. 2025 Jan-Dec;11:11 20552076251320302
    Data governance and open sharing in the fields of life sciences and medicine: A bibliometric analysis.
    Yanrui Qiu, Zhimin Hu.
       Objective: This study aims to conduct a bibliometric analysis of literature related to data governance and open sharing in the fields of life sciences and medicine, so as to clarify the characteristics of publications and explore research hotspots and trends.
    Methods: A total of 2529 valid documents published in the Web of Science Core Collection database from 2000 to 2024 were included in this study. VOSviewer was used for co-occurrence analysis, while CiteSpace was employed for clustering, burst detection, and thematic evolution analysis.
    Results: Between 2000 and 2024, the number of studies on data governance and open sharing in the fields of life sciences and medicine has increased annually, indicating the growing importance of research in this area. The USA led as the country with the most research output in this field. The University of Oxford was the institution with the highest publication volume, Amy L. McGuire was the most active author, and the Journal of Medical Internet Research and the Journal of the American Medical Informatics Association were the most frequent publication outlets. The most cited reference was 'Comment: The FAIR Guiding Principles for Scientific Data Management and Stewardship'.
    Conclusions: Topics such as the FAIR principles, ethical issues, public attitudes toward data sharing, data quality, databases, and big data analysis techniques are hotspots in this field. Potential research frontiers include the FAIR principles, data quality, public trust and attitudes toward data sharing, the application of artificial intelligence technology in data governance and sharing, governance and sharing of epidemiological and public health data, governance and sharing of data on chronic diseases such as diabetes, and the construction of data governance models.
    Keywords:  CiteSpace; Data governance; VOSviewer; bibliometric analysis; data open sharing; life sciences and medicine
    DOI:  https://doi.org/10.1177/20552076251320302
  28. Hum Vaccin Immunother. 2025 Dec;21(1): 2472493
    Global research progress in antibody-drug conjugates for solid tumors: Bibliometrics and visualized analysis.
    Wenjun Fang, Xueqing Ma, Ben Liu.
      Recently, the use of antibody-drug conjugates (ADCs) in the research and management of solid tumors has increased, making them a key focus in the field of oncology. In this study, we performed a comprehensive literature review of ADCs use in solid tumor treatment. We retrieved data from the Web of Science Core Collection (WoSCC). Following literature retrieval, we conducted a thorough bibliometric and knowledge-mapping analysis of the collected articles. There was a rapid growth in the number of annual publications in this field. The United States had the highest publication volumes and led ADC research for solid tumors. Additionally, The Dana-Farber Cancer Institute had the highest output, and G. Curigliano was identified as the most productive author. The journal "Cancers" led in the publishing of ADC research on solid tumors. Furthermore, key clustering terms such as "breast cancer," "targeted therapy," "bladder cancer," "ovarian cancer," "expression," and "drug delivery" emerged in this field as the research progressed. We identified six key themes by literature co-citation analysis, involving the research on the application of four ADCs in breast cancer, as well as the analysis of ADCs design, mechanisms, and strategies for reducing cytotoxicity. At the same time, based on the analysis of papers that have experienced a citation burst recently, we explored the future development trends of this field. Overall, our inaugural bibliometric analysis of ADCs for solid tumor research provides a systematic framework to guide future studies in this field. Therefore, facilitating and promoting further development in this area.
    Keywords:  ADCs; Antibody-drug conjugates; breast cancer; developing trends; solid tumors; visual analysis
    DOI:  https://doi.org/10.1080/21645515.2025.2472493
  29. Front Immunol. 2025 ;16 1476146
    Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study.
    Biling Gan, Lei Wu, Shunan Zhou, Zhihong Chen, Fan Wu, Lianqun Xu, Zhenrong Chen, Honghui Ma, Peijia He, Dan Fang, Ning Shi.
       Background: Hepatocellular carcinoma (HCC), a prevalent malignancy, is often diagnosed at advanced stages. Recent advances have integrated immunotherapy with targeted therapy, significantly improving treatment outcomes. This study provides a bibliometric overview of these therapeutic combinations, evaluating their development and impact.
    Methods: A rigorous selection process was applied to relevant literature from Web of Science, followed by in-depth bibliometric analyses- including timeline visualization, burst detection, and co-occurrence analysis-using CiteSpace and VOSviewer. This approach offered insights into the contributions of countries, institutions, authors, journals, references, and key terms within the field.
    Results: A total of 506 studies published between 2014 and 2023 were included, with all articles in English. Mainland China dominated the publication output, contributing 40% (N = 202), followed by significant contributions from the United States and Japan. Kindai University led institutional contributions, accounting for 7.9% of the total (N = 40). The authors Kudo Masatoshi and Hatanaka Takeshi were the most prolific, each with nine publications. The journal Cancers emerged as the top publisher, with 48 relevant articles and an Impact Factor of 5.2 in 2022. A co-citation network analysis traced the evolution of immunotherapy and targeted therapy combinations in HCC treatment. Early research primarily focused on angiogenesis, dendritic cells, and expression markers, while recent trends have shifted towards phase III trials, adverse reactions, and checkpoint inhibitors, underscoring the field's dynamic progression.
    Conclusion: Future research will expand on the pathological mechanisms underlying these therapies and novel interventions and combination strategies. Addressing adverse events and treatment discontinuation will remain central to advancing clinical applications.
    Keywords:  CiteSpace; VOSviewer; bibliometric study; combination therapy; hepatocellular carcinoma; immunotherapy; targeted therapy
    DOI:  https://doi.org/10.3389/fimmu.2025.1476146
  30. Front Immunol. 2025 ;16 1533651
    Bibliometric insight into neoadjuvant immunotherapy in non-small cell lung cancer: trends, collaborations, and future avenues.
    Pengliang Xu, Huanming Yu, Hupo Bian, Dan Jia, Wenhui Li, Hongfeng Dong, Xiuhua Peng.
       Background: Neoadjuvant immunotherapy (NIT) is a rapidly emerging paradigm for advanced resectable non-small cell lung cancer (NSCLC). However, there is no bibliometric analysis in this research field.
    Objective: To analyze the hotspots and trends in the research of NIT for NSCLC and provide a reference for the study of NIT for lung cancer in China.
    Methods: Retrieve literature related to NIT for NSCLC from Web of Science, PubMed, and Scopus databases up to September 10, 2024. Use CiteSpace and VOSviewer software visualization software to analyze the keywords of country, author, institution, and literature.
    Results: There were 1575 references, and the overall annual publication volume showed an upward trend; Forde and Patrick M have published the most articles in the literature. The research hotspots mainly focus on chemotherapy, NIT for NSCLC, immunotherapy, neoadjuvant chemotherapy, pathological reactions, etc.
    Conclusions: This is the first bibliometric study comprehensively summarizing NIT's research trends and development in NSCLC. Our bibliometric assessment provides a panoramic view of the research milieu surrounding NIT for NSCLC, encapsulating the present state, evolving trends, and potential future directions, particularly emphasizing the promise of immunochemotherapy.
    Keywords:  CiteSpace; chemotherapy; neoadjuvant immunotherapy; non-small cell lung cancer; visual analysis
    DOI:  https://doi.org/10.3389/fimmu.2025.1533651
  31. Hip Pelvis. 2025 Mar 01. 37(1): 45-52
    Bibliometric Analysis of Dual Mobility Total Hip Arthroplasty.
    Marc Boutros, Maroun Aoun, Fong H Nham, Eliana Kassis, Mohammad Daher, Mouhanad M El-Othmani.
       Purpose: For end stage arthritis of the hip joint, total hip arthroplasty (THA) is the treatment of choice. Dual mobility (DM) liner is an implant designed to provide enhanced stability. Long-term effects and implant survivability remain areas of active research despite modern advancements in increased jump distance and dislocation reductions. The aim of this study is to understand the current research landscape and emerging trends through a bibliometric analysis of DM THA.
    Materials and Methods: An analysis of THA DM publications from between 1982-2022 was conducted through an extensive review of Web of Science Core Collection literature. To identify key trends, contributions, and thematic areas of focus, data on publications, authors, institutions, and countries were extracted and analyzed.
    Results: The bibliographic search identified 314 articles, with a notable increase in publications over the period of study. Globally, the leading contributors were France and the USA. The analysis highlighted the Journal of Arthroplasty as the most relevant journal. Research themes included mechanical complications, comparative outcomes, metallosis, and corrosion concerns.
    Conclusion: This study provides a comprehensive DM THA research landscape overview highlighting postoperative outcome value. In an effort to guide future research, contributors, sources, and thematic trends were analyzed.
    Keywords:  Arthroplasty; Bibliometrics; Hip; Hip prosthesis; Review literature as topic
    DOI:  https://doi.org/10.5371/hp.2025.37.1.45
  32. Heliyon. 2025 Feb 15. 11(3): e42161
    The evolution of green finance research: A comprehensive bibliometric analysis.
    Guizhou Wang, Hongrui Cui, Kjell Hausken.
      The article investigates the evolution of green finance research through bibliometrics using 1923 publications from the Web of Science. It identifies key contributors, influential publications, and collaboration networks, while revealing three distinct research stages: (1) carbon finance and markets (2008-2010), (2) climate finance, climate policy, and climate change (2011-2017), and (3) sustainable development goals and financial development (2018-2022). Emerging topics such as green energy, green technology, carbon emissions, and the digital economy are highlighted. The result emphasizes the interdisciplinary nature of green finance, intersecting with environmental science, economics, and technology. The increasing publication and citation trends post-2019 reflect the growing importance of green finance in addressing global sustainability challenges. The findings offer valuable insights for researchers, policymakers, and practitioners, helping to identify knowledge gaps and future directions in green finance.
    Keywords:  Bibliometrics; Green finance; Qualitative analysis; Sustainable finance; green bonds
    DOI:  https://doi.org/10.1016/j.heliyon.2025.e42161
  33. Ren Fail. 2025 Dec;47(1): 2463583
    Bibliometric insights into systemic sclerosis with renal involvement: trends, contributions, and future directions.
    Haochen Huang, Ling-Ling Zhang, Jiaxin Zhou, Mengtao Li, Xiaofeng Zeng, Dong Xu.
       BACKGROUND: Renal involvement is not uncommon in patients with systemic sclerosis (SSc) and presents in various forms, particularly progressing to scleroderma renal crisis (SRC), which is associated with poor prognosis. Therefore, understanding the research trends in this field is critical for advancing clinical management and therapeutic strategies.
    METHODS: A bibliometric analysis was conducted using the Web of Science Core Collection, examining publications related to SSc and renal involvement from January 2000 to November 2024. We analyzed publication trends, key contributors, institutions, and countries.
    RESULTS: A total of 1,339 publications were identified in the field of SSc and renal involvement, demonstrating an upward trend in publication volume from 2000 to 2024. These articles have been cited a total of 61,234 times, with the majority of contributions coming from the United States, Italy, and East Asian countries. The University of Michigan and University College London were particularly prominent in terms of both publication volume and collaboration networks. Keyword analysis revealed a shift in research focus, with increasing attention on clinical aspects, pathophysiological mechanisms, and vascular complications.
    CONCLUSIONS: This study provides a comprehensive overview of the research landscape on SSc with renal involvement, highlighting the key contributors and emerging trends.
    Keywords:  Systemic sclerosis; bibliometric analysis; renal involvement; scleroderma renal crisis; vasculopathy
    DOI:  https://doi.org/10.1080/0886022X.2025.2463583
  34. COPD. 2025 Dec;22(1): 2441184
    Knowledge Domain and Emerging Trends in the Treatment of Patients with Chronic Obstructive Pulmonary Disease Combined with Respiratory Failure: A Scientometric Review Based on CiteSpace Analysis.
    Yabing Chen, Jiale Sang, Lingbo Fu, Ying Zhang.
       OBJECTIVE: To analyze the status of research on treating chronic obstructive pulmonary disease (COPD) combined with respiratory failure internationally to reveal its development trends through visualization methods and to provide a reference and suggestions for future research directions.
    METHODS: Literature on the treatment of COPD combined with respiratory failure published from the year of inception of the Web of Science database to December 31, 2023, was searched. CiteSpace 6.2.R7 software was used to visualize and analyze the published articles. A bibliometric analysis of the publications, keyword co-occurrence analysis, keyword clustering analysis, and keyword emergence analysis were performed to draw a correlation map and analyze the results.
    RESULTS: A total of 369 articles were analyzed. An overall increasing trend was observed in the number of publications. The network of researchers was relatively dense, and a core team was clearly observed. The researchers' affiliations were mainly European universities and hospitals, and close cooperation between institutions was observed. The keyword analysis obtained high-frequency keywords such as "noninvasive ventilation", "mechanical ventilation", and "positive pressure ventilation". The keyword clustering analysis revealed 10 clusters, and the keyword emergence analysis yielded 20 keywords.
    CONCLUSIONS: The focus of attention internationally has been on respiratory failure classification and types of ventilation support, such as high-flow oxygenation and noninvasive positive pressure ventilation. Future directions should include clinical research on high-flow oxygen administration to improve patient prognosis and the application of extracorporeal carbon dioxide removal technology to enhance patients' quality of life.
    Keywords:  Bibliometrics; CiteSpace; chronic obstructive pulmonary disease; respiratory failure; respiratory stimulant; therapy; visualization
    DOI:  https://doi.org/10.1080/15412555.2024.2441184
  35. Discov Oncol. 2025 Feb 28. 16(1): 255
    A 10-year bibliometric analysis in the field of osteosarcoma treatment from 2014 to 2023.
    Yiguo Shen, Xiaobo Shao, Jiansong Chen, Xin Tang.
       OBJECTIVE: This paper aims to explore the research hot spot and development trend in osteosarcoma treatment using a bibliometric method based upon Web of Science Core Collection (WoSCC) platform over the last decade.
    METHODS: The literature related to osteosarcoma and cure which were published from January 2014 to December 2023 were retrieved from the database of WoSCC and made an overall analysis for the papers published including number of articles, distribution of countries and institutions, author information, and keywords, with the CiteSpace 6.2.R5.
    RESULTS: A total of 3131 papers were retrieved, including 2601 articles and 530 reviews, and the number of papers published has been increasing year by year in the last decade. There were 415 countries and 10,719 research institutions participating into the study. China's output of literature was the highest relying on its 1490 papers published, followed by The United States (548 papers). Shanghai Jiaotong university had the largest number of papers published (121 papers) and Central South University ranked second (82 papers). A total of 16,816 authors participated in the study. The number of the paper published by Massimo Serra of the Rizzoli Orthopaedics Institute was the largest (27 papers), followed by Dominique Heymann of the University of Sheffield (20 papers). The visualization analysis of keywords by CiteSpace software showed that the drug resistance, drug delivery, tumor tissue engineering and gene expression have become hotspots in the field of osteosarcoma treatment. Drug resistance significantly limits the effectiveness of current cancer treatments. Drug delivery technology not only enhances the targeting and efficacy of drugs but also helps to overcome drug resistance. The stem cells, targeted therapy, and tumor microenvironment represent the new research trends. In particular, the tumor microenvironment plays a key role in tumor development, progression, and drug resistance, and it offers numerous potential therapeutic targets.
    CONCLUSION: Our investigation has identified key research foci and hotspots in osteosarcoma treatment, including drug resistance mechanisms, innovations in drug delivery technology, stem cell development, tumor microenvironment analysis, the development of novel therapies, and the clinical translation of tumor tissue engineering.
    Keywords:  Bibliometrics; CiteSpace; Osteosarcoma; Web of Science
    DOI:  https://doi.org/10.1007/s12672-025-02007-2
  36. Front Neurol. 2025 ;16 1469725
    A bibliometric analysis on delirium in intensive care unit from 2013-2023.
    Xin Ma, Qingya Wu, Yue Ran, Xueqin Cao, Hua Zheng.
       Background: Delirium is a common manifestation of acute brain dysfunction among patients in the Intensive Care Unit (ICU), afflicting an estimated 30-35% of this vulnerable population. The prevalence of delirium in ICU settings has catalyzed a surge in academic interest, as evidenced by a growing body of literature on the subject. This study seeks to synthesize the progress in understanding ICU delirium through a bibliometric analysis.
    Methods: We conducted a comprehensive search of the Web of Science Core (WOS) Collection database for literature on ICU delirium, focusing on studies published between 2013 and 2023. Our analysis utilized two bibliometric software tools, Citespace and VOSviewer, to scrutinize the data across various dimensions, including country contributions, authorship patterns, publishing journals, key thematic terms, and other pertinent metrics, with the aim of identifying emerging trends in the field.
    Results: Our search yielded a total of 1,178 publications on ICU delirium within the WOS database from January 2013 to June 2023. The United States emerged as the leading contributor in terms of published articles, with Ely, E. Wesley being the most prolific author, having published 85 articles, and "Critical Care Medicine" as the journal with the highest number of publications, totaling 105. The application of literature clustering and keyword analysis revealed that future research is poised to delve deeper into areas such as pediatric delirium, risk factors, and the development of preventive and therapeutic strategies.
    Conclusion: This study employs bibliometric analysis to provide a multifaceted overview of the ICU delirium research landscape over the past decade. By examining the topic from various perspectives, we have not only mapped the current state of ICU delirium research but also illuminated potential avenues for future inquiry and areas of emphasis.
    Keywords:  Citespace; ICU; VOSviewer; delirium; intensive care unit
    DOI:  https://doi.org/10.3389/fneur.2025.1469725
  37. Interact J Med Res. 2025 Feb 26. 14 e66286
    Current Status and Future Directions of Ferroptosis Research in Breast Cancer: Bibliometric Analysis.
    Jia-Yuan Luo, Yu-Long Deng, Shang-Yi Lu, Si-Yan Chen, Rong-Quan He, Di-Yuan Qin, Bang-Teng Chi, Gang Chen, Xia Yang, Wei Peng.
       BACKGROUND: Ferroptosis, as a novel modality of cell death, holds significant potential in elucidating the pathogenesis and advancing therapeutic strategies for breast cancer.
    OBJECTIVE: This study aims to comprehensively analyze current ferroptosis research and future trends, guiding breast cancer research advancements and innovative treatment strategies.
    METHODS: This research used the R package Bibliometrix (Department of Economic and Statistical Sciences at the University of Naples Federico II), VOSviewer (Centre for Science and Technology Studies at Leiden University), and CiteSpace (Drexel University's College of Information Science and Technology), to conduct a bibliometric analysis of 387 papers on breast cancer and ferroptosis from the Web of Science Core Collection. The analysis covers authors, institutions, journals, countries or regions, publication volumes, citations, and keywords.
    RESULTS: The number of publications related to this field has surged annually, with China and the United States collaborating closely and leading in output. Sun Yat-sen University stands out among the institutions, while the journal Frontiers in Oncology and the author Efferth T contribute significantly to the field. Highly cited papers within the domain primarily focus on the induction of ferroptosis, protein regulation, and comparisons with other modes of cell death, providing a foundation for breast cancer treatment. Keyword analysis highlights the maturity of glutathione peroxidase 4-related research, with breast cancer subtypes emerging as motor themes and the tumor microenvironment, immunotherapy, and prognostic models identified as basic themes. Furthermore, the application of nanoparticles serves as an additional complement to the basic themes.
    CONCLUSIONS: The current research status in the field of ferroptosis and breast cancer primarily focuses on the exploration of relevant theoretical mechanisms, whereas future trends and mechanisms emphasize the investigation of therapeutic strategies, particularly the clinical application of immunotherapy related to the tumor microenvironment. Nanotherapy has demonstrated significant clinical potential in this domain. Future research directions should deepen the exploration in this field and accelerate the clinical translation of research findings to provide new insights and directions for the innovation and development of breast cancer treatment strategies.
    Keywords:  China; United States; VOSviewer; advancements; bibliography; bibliometric; bibliometric analysis; breast cancer; breast carcinoma; cancer studies; disparities; ferroptosis; forecast; malignancy; mammary cancer; review; strategy; treatment; treatment strategies; trends
    DOI:  https://doi.org/10.2196/66286
  38. J Assist Reprod Genet. 2025 Feb 28.
    Silent battles, global insights: anxiety and depression in the world of assisted reproduction.
    Yongjia Zhou, Qingyong Zheng, Caihua Xu, Yiyi Li, Tengfei Li, Lin Li, Li Wang, Jinhui Tian, Guangmei Xie.
       PURPOSE: This study aims to summarize and analyze the existing research on anxiety and depression within the field of assisted reproduction technology, exploring current hotspots, emerging frontiers, and trends, while offering insights for future research directions.
    METHODS: Relevant literature on anxiety and depression among assisted reproduction patients was retrieved from the Web of Science Core Collection up to December 31, 2023. The analysis, encompassing studies, countries, authors, institutions, keywords, and co-citation networks, was visualized using VOSviewer version 1.6.19 and the "bibliometrix" R package version 4.3.1.
    RESULTS: A total of 1458 studies were included in the analysis. The literature on anxiety and depression in assisted reproduction patients has shown a fluctuating upward trend. Human Reproduction was identified as the leading journal, with the highest citations across multiple journals. Boivin J emerged as the most prolific author, with Cardiff University contributing the most publications. The USA and China led in terms of both publications and citations. Highly cited studies were predominantly published between 1995 and 2007, with half of the included studies published before 2000. Key research hotspots included evidence synthesis, acupuncture treatment for infertility, and the mental health of patients undergoing assisted reproductive technology, particularly focusing on anxiety and depression.
    CONCLUSION: As awareness of psychological health in assisted reproductive technology continues to grow, future research should focus on mitigating anxiety and depression to enhance patient outcomes and patient quality of life. Integrating psychological support and monitoring long-term psychological outcomes are crucial for optimizing assisted reproductive technology success and fostering holistic, patient-centered care.
    Keywords:  Anxiety; Assisted reproductive technology; Bibliometric analysis; Depression
    DOI:  https://doi.org/10.1007/s10815-025-03422-8
  39. World J Urol. 2025 Feb 26. 43(1): 140
    Application trends and research hotspots of endoscopic enucleation of the prostate: a bibliometric and visualization analysis.
    Xiao-Da Lan, Zhuo-Yang Yu, Rui Jiang, Zhi-Cun Li, Lei Yang, Kai Zhang, Yi-Sen Meng, Qian Zhang.
       PURPOSE: Endoscopic enucleation of the prostate (EEP) is a preferred treatment for benign prostatic hyperplasia (BPH). This bibliometric analysis aims to analyze the application trends and research hotspots of EEP.
    METHODS: We conducted a bibliometric analysis of publications indexed in the Web of Science Core Collection from 1989 to 2023. The techniques examined include holmium laser enucleation (HoLEP), thulium laser enucleation (ThuLEP/ThuFLEP), bipolar/monopolar transurethral enucleation (b-TUEP/m-TUEP), GreenLight laser enucleation (GreenLEP), and diode laser enucleation (DiLEP). We utilized VOSviewer, CiteSpace, and the R package 'bibliometrix' for the analysis.
    RESULTS: A total of 739 English-language studies were analyzed, revealing a steady increase in EEP-related publications. HoLEP was the most extensively studied technique, followed by ThuLEP and b-TUEP, while ThuFLEP gaining emerging interest. There has been a notable lack of high-quality randomized controlled trials (RCTs) for GreenLEP, DiLEP and m-TUEP. China, the United States, and Germany led in publication volume and collaboration networks. Key contributors in the field were identified, with recent research focusing on topics like postoperative transient urinary incontinence (TUI) and the role of robot-assisted simple prostatectomy (RASP) in comparison to EEP.
    CONCLUSIONS: EEP is gaining widespread clinical acceptance for BPH treatment. Future research should focus on addressing the gap in high-quality RCTs, especially for underexplored techniques like GreenLEP, DiLEP and m-TUEP, and explore strategies to reduce postoperative TUI. Prospective comparisons between RASP and EEP will be crucial for optimizing surgical approaches in BPH management.
    Keywords:  Benign prostatic hyperplasia; Endoscopic enucleation; HoLEP; Laser enucleation; ThuLEP
    DOI:  https://doi.org/10.1007/s00345-024-05379-2
  40. World Neurosurg. 2025 Feb 21. pii: S1878-8750(25)00173-1. [Epub ahead of print] 123817
    Global hotspots and research frontiers of Moyamoya disease and radiological features: A bibliometric analysis.
    Baobao Li, Mingming Lu, Ziai Zhao, Shengshu Wang, Yuan Liu, Shitong Liu, Hongtao Zhang, Fugeng Sheng, Jianming Cai.
       BACKGROUND: Moyamoya disease (MMD) is a cerebrovascular disorder characterized by the progressive stenosis of the intracranial internal carotid artery and the development of a collateral network in the brain. As medical imaging technology and artificial intelligence have advanced, various imaging methods have been widely used in the clinical diagnosis of MMD. In this study, we conducted bibliometric visualization of research papers about MMD and radiological features between 2000 and 2024, intending to explore the development status quo, hotspots, and future developments and contributing to studies on imaging in diagnosis of cerebrovascular diseases.
    METHODS: The Web of Science Core Collection was chosen as the source of publications for this study. By using VOSviewer and CiteSpace, articles were analyzed in terms of authors, countries, institutions, references, keywords, cited literatures, and so on.
    RESULTS: We retrieved a collection of 1003 articles that substantiate a progressively ascendant trend in articles over the past 24 years. Japan, South Korea, and China were three major countries in this field. China's Capital Medical University was the leader in publication output, followed by Hokkaido University from Japan and Seoul National University from South Korea. The three authors with the most publications were Miki Fujimura, Teiji Tominaga, and Dong Zhang. World Neurosurgery was the journal with the most publications (85), while Stroke was the journal with the most co-citations (3305) in this field. Excluding MMD, the top three most frequently occurring keywords were "revascularization", "stroke", and "magnetic resonance imaging (MRI)". "High-resolution magnetic resonance imaging (HRMRI)", "digital subtraction angiography (DSA)", and "vessel wall imaging" were the top three keywords of recent interest in the field of radiological features.
    CONCLUSION: This article provides a scientific perspective from which researchers, especially doctors in neurosurgery and radiodiagnosis departments can visually find out about important trends and new areas of research directions in the field of MMD and radiological features.
    Keywords:  CiteSpace; Moyamoya disease; VOSviewer; bibliometric analysis; radiological features
    DOI:  https://doi.org/10.1016/j.wneu.2025.123817
  41. Acta Psychol (Amst). 2025 Feb 22. pii: S0001-6918(25)00135-0. [Epub ahead of print]254 104822
    I do not think before I leap (buy)! Impulse buying: An integrative review and future research directions.
    Mohita Maggon.
      The aim of this paper was to use bibliometric analysis to fill a gap in the research and provide a detailed review of the impulse buying (IB) literature. A total of 541 journal articles published between 2014 and 2023 were retrieved from Scopus and systematically analyzed. The findings indicate that IB has received ample attention in previous studies. Four prominent clusters were identified using co-citation network analysis. The United States was the most influential country, with the most publications and citations in terms of IB research. In the past, authors have analyzed many factors that influence IB. However, some research areas remain underexplored, such as the impacts of the metaverse, artificial intelligence, and live commerce on IB. The findings have relevant implications for psychologists who focus on IB. IB is a crucial concept relevant to psychology and marketing researchers interested in uncovering novel psychological dimensions and requires timely reviews. Previous reviews have either been descriptive/conceptual (literature reviews re-examining and defining the construct) or contextual (meta-analyses of impulse buying in hospitality). To the best of our knowledge, this is the first study to explore IB's past, present, and future using bibliometric and content analysis across various online and offline buying platforms.
    Keywords:  Addiction; Bibliometric analysis; Impulse buying; Integrative review; Pathological buying
    DOI:  https://doi.org/10.1016/j.actpsy.2025.104822
  42. Front Med (Lausanne). 2025 ;12 1498503
    Efferocytosis and inflammation: a bibliometric and systematic analysis.
    Xin Cao, Fen Li, Xi Xie, Guanghui Ling, Xiaoyu Tang, Wenfang He, Jing Tian, Yan Ge.
       Objective: To visualize and analyze the trends and hotspots of efferocytosis and inflammation via bibliometric methods.
    Methods: Relevant articles and reviews from 2006 to 2023 were retrieved from the Web of Science Core Collection. The data were processed with CiteSpace, and some graphs were generated with Microsoft Excel (version 2016), VOSviewer, Scimago Graphica, Bibliometrix and R Studio.
    Results: A total of 1,003 papers were included, revealing a significant upward trend in efferocytosis and inflammation research. The United States (456, 45.46%), China (164, 16.35%) and the United Kingdom (99, 9.87%) were the three countries with the highest numbers of publications. Harvard University (84, 6.74%) contributes the most out of the top 5 institutions. Among the researchers in this field, Serhan CN was the author with the highest number of articles in the field (35, 3.49%), and deCathelineau AM first named "efferocytosis" in 2003. Keyword analysis identified "activation," "tam receptors," "docosahexaenoic acid" "systemic lupus erythematosus," "myocardial infarction" and "alveolar macrophages" as core topics, indicating a concentrated trend in the mechanism of physiological state and inflammatory diseases such as autoimmune, cardiovascular, and pulmonary diseases. The latest surge words "inflammation resolution" and "cancer" in the keyword heatmap indicate future research directions.
    Conclusion: Research on the association between efferocytosis and inflammation has been a promising field. Key areas of focus include the crucial role of efferocytosis on tissue homeostasis and the pathogenesis of nontumorous inflammatory diseases. Future research will likely continue to explore these frontiers, with an emphasis on understanding efferocytosis in the context of chronic diseases and cancer, as well as developing novel therapeutic strategies.
    Keywords:  bibliometrics; cancer; efferocytosis; inflammation; mesenchymal stem cells; molecular mechanism; nontumorous inflammatory diseases
    DOI:  https://doi.org/10.3389/fmed.2025.1498503
  43. Front Psychol. 2025 ;16 1520937
    Bibliometric analyses of climate psychology: critical psychology and climate justice perspectives.
    Gulnaz Anjum, Mudassar Aziz.
      The psychology of climate change has become a critical area of research, exploring the intersection between human behavior, psychological wellbeing, and environmental sustainability. This paper presents a bibliometric analysis to explore the interdisciplinary field of psychology and climate change, covering research from 01 January 1995 to 15 August 2024. Using 3,087 academic publications from the Web of Science and employing VOSviewer and BiblioMatrix for network analysis, we dissect the evolution, key contributors, and central themes within this domain. Our analysis identifies leading authors, institutions, and nations, alongside the collaboration networks underlying the field's growth. Thematic clustering of these networks highlights dominant topics such as pro-environmental behavior, sustainability, mental health, eco-anxiety, and risk perception. We utilize visual mappings of co-authorship and bibliographic relationships to illustrate the dynamic interaction among researchers and their topics. By framing our findings through the lens of climate justice and critical psychology, we advocate for a research paradigm that challenges systemic barriers to climate justice, emphasizing the necessity for equitable and action-oriented psychological research to guide climate-related policy and public engagement.
    Keywords:  bibliometric analysis; climate change; climate justice; climate psychology; critical psychology; eco-anxiety; mental health; research equity
    DOI:  https://doi.org/10.3389/fpsyg.2025.1520937
  44. Can Assoc Radiol J. 2025 Feb 28. 8465371251324099
    Trends in Interventional Radiology: A Bibliometric Analysis of the Canadian Association of Radiologists Journal.
    Ali Helmi, Sabreena Moosa, Sebastian Charles Mafeld.
      
    DOI:  https://doi.org/10.1177/08465371251324099
  45. Eur Arch Otorhinolaryngol. 2025 Feb 17.
    Artificial intelligence in otorhinolaryngology: current trends and application areas.
    Emre Demir, Burak Numan Uğurlu, Gülay Aktar Uğurlu, Gülçin Aydoğdu.
       PURPOSE: This study aims to perform a bibliometric analysis of scientific research on the use of artificial intelligence (AI) in the field of Otorhinolaryngology (ORL), with a specific focus on identifying emerging AI trend topics within this discipline.
    METHODS: A total of 498 articles on AI in ORL, published between 1982 and 2024, were retrieved from the Web of Science database. Various bibliometric techniques, including trend keyword analysis and factor analysis, were applied to analyze the data.
    RESULTS: The most prolific journal was the European Archives of Oto-Rhino-Laryngology (n = 67). The USA (n = 200) and China (n = 61) were the most productive countries in AI-related ORL research. The most productive institutions were Harvard University / Harvard Medical School (n = 71). The leading authors in this field were Lechien JR. (n = 18) and Rameau A. (n = 17). The most frequently used keywords in the AI research were cochlear implant, head and neck cancer, magnetic resonance imaging (MRI), hearing loss, patient education, diagnosis, radiomics, surgery, hearing aids, laryngology ve otitis media. Recent trends in otorhinolaryngology research reflect a dynamic focus, progressing from hearing-related technologies such as hearing aids and cochlear implants in earlier years, to diagnostic innovations like audiometry, psychoacoustics, and narrow band imaging. The emphasis has recently shifted toward advanced applications of MRI, radiomics, and computed tomography (CT) for conditions such as head and neck cancer, chronic rhinosinusitis, laryngology, and otitis media. Additionally, increasing attention has been given to patient education, quality of life, and prognosis, underscoring a holistic approach to diagnosis, surgery, and treatment in otorhinolaryngology.
    CONCLUSION: AI has significantly impacted the field of ORL, especially in diagnostic imaging and therapeutic planning. With advancements in MRI and CT-based technologies, AI has proven to enhance disease detection and management. The future of AI in ORL suggests a promising path toward improving clinical decision-making, patient care, and healthcare efficiency.
    Keywords:  AI; Artificial intelligence; Bibliometric analysis; Deep learning; Otorhinolaryngology; Research trends
    DOI:  https://doi.org/10.1007/s00405-025-09272-5
  46. Int Urol Nephrol. 2025 Feb 28.
    Global research trends on the associations between chronic kidney disease and mitochondria: insights from the bibliometric analysis.
    Xinfang Tang, Anna Zhang, Xiaojuan Feng, Wenjuan Wang, Fanghong Chen, Yijie Tao, Chuyan Wu, Feng Jiang.
       BACKGROUND: Chronic kidney disease (CKD) is a global health burden characterized by a progressive and irreversible loss of kidney function. Mitochondrial dysfunction has emerged as a pivotal factor in CKD pathogenesis, contributing to renal cell injury, inflammation, and fibrosis through mechanisms such as oxidative stress and impaired bioenergetics. This study aimed to provide a comprehensive bibliometric analysis of global research trends on the associations between CKD and mitochondria over the past two decades.
    METHODS: A bibliometric analysis was conducted using the Web of Science Core Collection database, focusing on publications from 2004 to 2024. Data were analyzed using Citespace and VOSviewer to visualize publication trends, key contributors, keyword co-occurrences, and collaboration networks.
    RESULTS: A total of 2,870 publications were identified, with a significant increase in annual output observed after 2010. The United States, China, and Japan were the leading contributors, fostering strong international collaborations. Institutional analysis highlighted the prominent roles of the US Department of Veterans Affairs and the University of California System. Key authors, such as Jose Pedraza-Chaverri and HM Kang, and influential studies addressing mitochondrial quality control and metabolic reprogramming were identified. Keyword analysis revealed major research themes, including oxidative stress, ischemia-reperfusion injury, and fatty acid oxidation, with recent trends emphasizing mitochondrial dynamics and autophagy.
    CONCLUSIONS: This analysis underscored the growing recognition of mitochondrial dysfunction in CKD pathogenesis and highlighted the interdisciplinary nature of this field. The findings revealed key research trends, influential contributors, and emerging topics, providing a foundation for future studies and the development of targeted mitochondrial therapies. These insights hold promise for advancing the understanding and treatment of CKD through precision medicine approaches. Specifically, therapeutic strategies aimed at enhancing mitochondrial biogenesis, promoting mitophagy, and restoring metabolic balance may offer novel avenues for delaying CKD progression and mitigating renal dysfunction. Integrating these mitochondrial-targeted interventions into current clinical practice could improve patient outcomes and guide the development of more effective treatment protocols.
    Keywords:  Bibliometric analysis; Chronic kidney disease; Mitochondria; Mitochondrial dysfunction; Oxidative stress; Research trends
    DOI:  https://doi.org/10.1007/s11255-025-04437-x
  47. Front Neurol. 2025 ;16 1496526
    The role of glial cells in neuralgia: a bibliometric exploration.
    Ting He, DongDong Wang, Linman Wu, Liuyin Jin.
      Neuropathic pain is a chronic pathological pain caused by nervous system damage, characterized by complex mechanisms and limited treatment efficacy. Glial cells play a pivotal role in the initiation and maintenance of neuropathic pain. This study employs bibliometric analysis to explore trends and emerging hotspots in research on the relationship between glial cells and neuropathic pain. Based on literature data from the Web of Science Core Collection spanning 2003 to 2022, the study identifies key contributors in the field, including leading countries such as China, the United States, and Japan, as well as influential institutions and journals, such as the University of California system and Pain. Keyword analysis highlights research hotspots focusing on glial cell activation, spinal cord injury, satellite glial cells, oxidative stress, and neuroinflammation. The findings suggest that these themes may shape future directions in the field. This study provides researchers with a comprehensive overview of trends and hotspot analysis, offering valuable insights for further investigation into the role of glial cells in neuropathic pain.
    Keywords:  bibliometrics; data visualization; glia; neuralgia; neuropathic pain; research hotspots
    DOI:  https://doi.org/10.3389/fneur.2025.1496526
  48. Cad Saude Publica. 2025 ;pii: S0102-311X2025000101413. [Epub ahead of print]41(1): e00020824
    Research on neglected tropical diseases in Haiti: a scientometrics analysis, 1923-2022.
    Melicile Glesil, Adjoane Maurício Silva Maciel, Taynara Lais Silva, Anderson Fuentes Ferreira, Aymee Medeiros da Rocha, Gabriela Soledad Márdero García, Evens Emmanuel, Max François Millien, Jorg Heukelbach, Eliana Amorim de Souza, Ana Raquel da Silva Paz, Alberto Novaes Ramos.
      This study aimed to analyze scientometric profile of publications on neglected tropical diseases (NTDs) in Haiti, 1923-2022. We conducted a scientometric study based on indexed scientific productions related to NTDs in Haiti. The search syntax in the Scopus database was based on key terms for NTDs recognized by the World Health Organization in 2022, focusing on keywords, titles, and abstracts. VOSviewer 1.6.18 was used to create bibliographic networks according to authorship, country of origin, institution, and descriptors. A total of 281 publications were identified, 87.9% (247/281) original articles, with an increase of 45.1% (127/281, annual average of 12.7 publications) in the last decade (2013-2022) compared to the first half of the analyzed period (1923-1975, annual average of 0.21 publications). The authors with the highest number of publications were: Lammie PJ (n = 51), Eberhard ML (n = 29), and Wallace RM (n = 25). A total of 83 institutions participated in the research and the Centers for Disease Control and Prevention (United States) had the highest proportion of affiliations in the coauthorship versus organizations analysis (n = 86), with authors from 35 countries. Coauthorship by country shows publications between institutions in the Americas (n = 13), Europe (n = 9), and Asia (n = 5). The analysis of cooccurrence versus author keywords shows higher occurrence of the terms "dengue" and "rabies". There is a very limited number of publications on NTDs in Haiti throughout a century of publications, despite the relative increase in recent decades. Such publications are concentrated among foreign authors, with limited national coauthorship.
    DOI:  https://doi.org/10.1590/0102-311XEN020824
  49. Neuroradiol J. 2025 Feb 26. 19714009251324292
    Characteristics of highly cited articles in cerebral angiography.
    Hafiz Muhammad Sameer, Syed Abdullah Arif, Aribah Bhatti, Faraz Arshad, Khadija Ali.
       OBJECTIVE: To present and analyze the characteristics of the 100 most cited articles that used cerebral angiography for clinical evaluation and intervention.
    METHOD: Two researchers independently extracted articles from multiple databases and ranked them by citation count to create the "top 100 most-cited" list.
    RESULTS: The top 100 articles received a total of 115,243 citations. Twenty-one of the top 100 articles were published between 2006 and 2010. Most studied disorder was ischemic stroke (n = 35), and cerebral angiography was used most frequently for diagnosis (n = 88).The United States was affiliated with the highest number of articles (n = 62), with Stroke publishing most articles (n = 22). Public sources funded 39 articles, private sources funded 35, and 38 articles reported conflicts of interest. Thirty-six studies were randomized controlled trials, and male authors held the majority of both first (n = 90) and senior (n = 88) authorship positions.
    CONCLUSION: Within the scope of this study, the following features may define a typical highly cited article-a randomized controlled clinical trial conducted in the United States that studied ischemic stroke, used cerebral angiography for diagnosis, and was published relatively recently in a high-impact journal by male first and senior authors.
    Keywords:  Cerebral angiography; bibliometrics; interventional radiography
    DOI:  https://doi.org/10.1177/19714009251324292
  50. Front Pharmacol. 2025 ;16 1528459
    Profile of STING agonist and inhibitor research: a bibliometric analysis.
    Xuemei Wang, Qian Wang, Yidan Gao, Lijuan Jiang, Lingli Tang.
       Background: STING is a core signaling hub molecule in the innate immune system, involved in various diseases, including infectious diseases, autoimmune diseases, tumors, aging, organ fibrosis, and neurodegenerative diseases. Its activation has shown great potential in anti-tumor and anti-infective therapies, with STING agonists emerging as a promising approach in cancer immunotherapy in recent years. This study identifies research trends and potential directions in the field by collecting and analyzing relevant literature.
    Methods: A total of 527 publications regarding STING agonists and 107 about inhibitors were retrieved from the WOS Core Collection database. Bibliometric information was extracted with CiteSpace and VOSviewer software for visualization.
    Results: It shows that research on both STING agonists and inhibitors is burgeoning rapidly. The United States and China are leading contributors in this field. Application of STING agonists primarily focuses on cancer immunotherapy, while STING inhibitors target inflammation, particularly neuroinflammation and acute lung injury.
    Conclusion: Current research emphasizes optimizing STING agonists for permeability, efficacy, and safety, with nanotechnology and lipid nanoparticles being prominent delivery techniques. Future research is expected to focus on drug development and clinical applications. This comprehensive bibliometric analysis provides clinical insights and a guide for further investigation to STING agonist/inhibitor.
    Keywords:  STING agonist; STING inhibitor; bibliometric analysis; cancer immunotherapy; innate immune
    DOI:  https://doi.org/10.3389/fphar.2025.1528459
  51. Front Cardiovasc Med. 2025 ;12 1521464
    The role of artificial intelligence in aortic valve stenosis: a bibliometric analysis.
    Shanshan Chen, Changde Wu, Zhaojie Zhang, Lingjuan Liu, Yike Zhu, Dingji Hu, Chenhui Jin, Haoya Fu, Jing Wu, Songqiao Liu.
       Purpose: To explore the expanding role of artificial intelligence (AI) in managing aortic valve stenosis (AVS) by bibliometric analysis to identify research trends, key contributors, and the impact of AI on enhancing diagnostic and therapeutic strategies for AVS.
    Methods: A comprehensive literature review was conducted using the Web of Science database, covering publications from January 1990 to March 2024. Articles were analyzed with bibliometric tools such as CiteSpace and VOSviewer to identify key research trends, core authors, institutions, and research hotspots in AI applications for AVS.
    Results: A total of 118 articles were analyzed, showing a significant increase in publications from 2014 onwards. The results highlight the growing impact of AI in AVS, particularly in cardiac imaging and predictive modeling. Core authors and institutions, primarily from the U.S. and Germany, are driving research in this field. Key research hotspots include machine learning applications in diagnostics and personalized treatment strategies.
    Conclusions: AI is playing a transformative role in the diagnosis and treatment of AVS, improving accuracy and personalizing therapeutic approaches. Despite the progress, challenges such as model transparency and data security remain. Future research should focus on overcoming these challenges while enhancing collaboration among international institutions to further advance AI applications in cardiovascular medicine.
    Keywords:  aortic valve stenosis; artificial intelligence; bibliometrics; clinical decision support; machine learning
    DOI:  https://doi.org/10.3389/fcvm.2025.1521464
  52. J Med Radiat Sci. 2025 Feb 25.
    Evaluation of New Zealand's Radiology, Nuclear Medicine, and Medical Imaging Research Output: A Bibliometric-Based Approach.
    Vicky Li, Sibusiso Mdletshe.
       INTRODUCTION: The use of medical imaging services has increased globally with a concurrent increase in radiology, nuclear medicine and medical imaging (RNMI) research. However, New Zealand's RNMI research output relative to global trends is under-examined. This project evaluates New Zealand's RNMI research output between 1996 and 2022 compared to selected countries while highlighting global RNMI research output trends.
    METHODS: A bibliometric-based performance analysis was conducted using publication data from the SCImago Journal, the Country Rank portal, Clarivate InCites Benchmarking, and the Analytics platform. Registration data of RNMI professionals by country was collected to evaluate the relationship between research output and the number of registered professionals.
    RESULTS: Among the seven selected countries (the United States, United Kingdom, Canada, Australia, Ireland, New Zealand and South Africa), New Zealand's research output was low, even when adjusted for population size and the number of professionals. A significant positive correlation was found between the number of registered RNMI professionals and the number of RNMI publications. Despite this, New Zealand had the highest percentage of RNMI documents cited.
    CONCLUSION: Although New Zealand's RNMI publications follow the global upward trend, it does so at a proportionate loss. New Zealand ranked low in most bibliometric indicators apart from the percentage of documents cited, where it showed a notable citation impact. Emphasising research, increasing collaborative efforts, and undertaking further statistical analyses may enhance New Zealand's RNMI research output.
    Keywords:  Reporting; Research; Review; Writing
    DOI:  https://doi.org/10.1002/jmrs.875
  53. J Psychosoc Nurs Ment Health Serv. 2025 Feb 26. 1-12
    AI-Augmented Psychosocial Interventions: A Bibliometric Review and Implications for Nursing.
    Erman Yıldız.
       PURPOSE: To map out the current artificial intelligence (AI)-informed psychosocial interventions research landscape, with a focus on main themes, trends, and prospective future directions.
    METHOD: A bibliometric analysis extracted articles that had been published between 2007 and 2024 from the Web of Science database. Software used to process results were Bibliometrix and VOSviewer.
    RESULTS: A total of 207 articles published by 86 different sources were obtained. A publication of high recurrence source was the Journal of Medical Internet Research. The United States showed high research activity in link strength, volume of articles, and citation frequency. Key themes identified were machine learning, mental health, cognitive-behavioral therapy, and personalization. Emerging trends since 2020 show growing interest in ChatGPT and AI-driven therapy.
    CONCLUSION: Bibliometric analysis suggests increased application of AI in psychosocial interventions in mental health. Integrating AI with existing therapies and the development of novel digital tools indicate a future for mental health care that is personalized and innovative. The advent of advanced language models, such as ChatGPT, has opened new horizons in AI-supported mental health care. This preliminary analysis provides a foundational understanding of the current landscape while identifying key areas for further research. [Journal of Psychosocial Nursing and Mental Health Services, xx(xx), xx-xx.].
    DOI:  https://doi.org/10.3928/02793695-20250214-01
  54. World J Clin Oncol. 2025 Feb 24. 16(2): 98983
    Mapping the landscape of gastric signet ring cell carcinoma: Overcoming hurdles and charting new paths for advancement.
    Shu-Yuan Wang, Jing-Hang Wang, Run-Kai Chen, Zhen Yuan, Hao Cui, Bo Wei, Jian-Xin Cui.
       BACKGROUND: In recent years, the global prevalence of gastric cancer (GC) has witnessed a progressive decrease, accompanied by a step-growth in the incidence of gastric signet ring cell carcinoma (GSRCC). As precision medicine concepts progress, GSRCC, a distinct sub-type of GC, has drawn considerable attention from researchers. However, there still persist some controversies regarding the associated research findings.
    AIM: To summarize the current obstacles and potential future directions for research on GSRCC.
    METHODS: To begin with, all literature related to GSRCC published from January 1, 2004 to December 31, 2023 was subjected to bibliometric analysis in this article. Additionally, this paper analyzed the research data using CiteSpace, GraphPad Prism v8.0.2, and VOSviewer, which was obtained from the Web of Science Core Collection database. The analysis results were visually represented.
    RESULTS: This study provided a comprehensive overview of the statistical characteristics of the 995 English articles related to GSRCC, including cited references, authors, journals, countries, institutions, and keywords. The popular keywords and clusters contain "prognosis", "survival", "expression", "histology", and "chemotherapy".
    CONCLUSION: The prognosis, precise definition and classification, as well as chemoresistance of GSRCC, continue to be crucial areas of ongoing research, whose directions are closely tied to advancements in molecular biology research on GSRCC.
    Keywords:  Bibliometric analysis; CiteSpace; Gastric cancer; Signet ring cell carcinoma; VOSviewer
    DOI:  https://doi.org/10.5306/wjco.v16.i2.98983
  55. Foods. 2025 Feb 15. pii: 663. [Epub ahead of print]14(4):
    Edible Insects: Global Research Trends, Biosafety Challenges, and Market Insights in the Mexican Context.
    Keyla Cruz-García, Yolanda Donají Ortiz-Hernández, Marco Aurelio Acevedo-Ortiz, Teodulfo Aquino-Bolaños, Tlacaelel Aquino-López, Gema Lugo-Espinosa, Fernando Elí Ortiz-Hernández.
      The growing global interest in edible insects as a sustainable protein source has positioned them as a promising solution to food security challenges. In Mexico, entomophagy is deeply embedded in cultural traditions, particularly in Oaxaca, where grasshoppers, leafcutter ants, and red agave worms form an integral part of the region's intangible heritage. This study conducted a bibliometric analysis of global research on edible insects (2009-2023) using Scopus and tools such as VOSviewer and Bibliometrix to analyze 218 publications. The analysis highlighted research trends, influential authors, and key themes, including nutrition, biosafety, and sustainability. To complement the bibliometric study, an exploratory analysis of edible insect commercialization in Oaxaca was conducted, focusing on virtual platforms and local markets. The findings reveal consistent global growth in edible insect research, with Mexico contributing six publications between 2020 and 2023. Despite advancements in safety standards and regulatory frameworks globally, Mexico still lacks formal sanitary controls and regulations for insect-based products. Nevertheless, its diverse commercialization efforts and rich cultural heritage, particularly in Oaxaca, showcase its potential to bridge tradition and innovation. This study highlights the urgent need for regulatory frameworks and research capacity to ensure safety, preserve cultural identity, and sustainably expand Mexico's edible insect market.
    Keywords:  bibliometric analysis; biosafety; edible insects; entomophagy; food security; global trends; sustainable protein
    DOI:  https://doi.org/10.3390/foods14040663
  56. Eur J Orthop Surg Traumatol. 2025 Feb 27. 35(1): 81
    Factors for predicting time to acceptance in the journal of the American academy of orthopaedic surgeons.
    Ethan Crawford, Maria Gergoudis, Sarah Whitaker, Logan Laubach, Teja Yeramosu, Nirav Patel.
       PURPOSE: The Journal of the American Academy of Orthopaedic Surgeons (JAAOS) is a high-impact journal that publishes crucial research to inform surgeons' clinical decision-making. The purpose of this study was to determine the median time from submission to acceptance for articles published by the JAAOS and to evaluate factors which may influence time to acceptance.
    METHODS: All studies published in JAAOS from 2020 to 2022 were obtained. Abstracts were screened for submission and acceptance dates, and time to acceptance was calculated. Studies were excluded if dates were unavailable. Data extracted included article type, main topic, and sex of the first author. Simple linear regression, analysis of variance (ANOVA), and independent samples t-test were utilized for univariate analysis. For multivariate analyses, a standard least squares regression was applied.
    RESULTS: We analyzed 754 articles. Over the past 3 years, time to acceptance has not significantly changed (p = 0.894). Regarding article type, letters had the shortest time to acceptance (median 5 days, IQR 2-10, p < 0.0001), while interventional studies had the longest time to acceptance (median 171.5 days, IQR 106-309.5. Articles pertaining to COVID-19 (median 62 days, IQR 2-121) and diversity (median 90 days, IQR 24-156) had the shortest times to acceptance. Articles pertaining to radiology (median 189.5 days, IQR 100-309.5) and trauma (median 183 days, IQR 126.5-269.5) had the longest times to acceptance (p < 0.0008). Time to acceptance was not significantly different between male and female first authors.
    CONCLUSION: This study provides a tool for authors to estimate their mean time from submission to acceptance based on the characteristics of their study. With literature submissions constantly increasing each year with unknown times to acceptance, authors may make a more informed decision with journal selection based on the qualities of their study.
    Keywords:  Article topic; Article type; Author sex; Bibliometric analysis; Time to acceptance; Time to publication
    DOI:  https://doi.org/10.1007/s00590-025-04178-8
  57. Diagnostics (Basel). 2025 Feb 19. pii: 504. [Epub ahead of print]15(4):
    Trends in Clinical Cardiac Photon-Counting Detector CT Research: A Comprehensive Bibliometric Analysis.
    Arosh S Perera Molligoda Arachchige, Federica Catapano, Costanza Lisi, Jad El Choueiri, Francesca Pellicanò, Stefano Figliozzi, Letterio S Politi, Marco Francone.
      Photon-counting detector computed tomography (PCD-CT) represents a significant advancement in radiological imaging, offering substantial potential for cardiac applications that remain partially underexplored. This bibliometric analysis investigates the evolution and current clinical application of cardiac PCD-CT by examining research trends from 2019 to 2024. The analysis aims to understand the development of this technology, its clinical implications, and future directions. A comprehensive literature search was conducted using databases such as PubMed, EMBASE, Scopus, and Google Scholar, yielding 984 records. After removing duplicates and applying inclusion criteria, 81 studies were included in the final analysis. These studies primarily focused on coronary artery calcium scoring, coronary atherosclerotic plaque assessment, and coronary artery stenosis quantification. The findings indicate a significant upward trend in the number of publications, peaking in 2023. The bibliometric analysis revealed that the USA, Germany, and Switzerland are the leading contributors to PCD-CT research, with prominent institutions like the Mayo Clinic and the University of Zurich driving advancements in the field. The NAEOTOM Alpha by Siemens Healthineers, being the only commercially available PCD-CT model, highlights its central role in cardiac imaging studies. Funding for PCD-CT research came from various sources, including industry leaders like Siemens and Bayer, as well as governmental and academic institutions. The analysis also identified several challenges that PCD-CT research faces, including the need for larger patient cohorts and broader geographical representation. In conclusion, the rapid growth of cardiac PCD-CT research underscores its transformative potential in clinical practice. Continued investment, collaboration, and extensive research are essential to fully harness the benefits of PCD-CT.
    Keywords:  applications; bibliometric; cardiac imaging; clinical; meta-analysis; photon-counting detector CT
    DOI:  https://doi.org/10.3390/diagnostics15040504
  58. Front Cardiovasc Med. 2025 ;12 1426583
    Angiogenesis after acute myocardial infarction: a bibliometric -based literature review.
    Yu Tan, Min Li, Xiaojuan Ma, Dazhuo Shi, Wei Liu.
       Objective: The prevalence of acute myocardial infarction, a severe ischemic cardiac disease, is on the rise annually. The establishment of coronary collateral circulation in the border zone of the infarct can effectively relieve myocardial ischemia and impede cell death, while angiogenesis can promote the formation of collateral circulation in the ischemic tissues. Over the past two decades, studies related to angiogenesis in acute myocardial infarction have increased rapidly. However, there is a lack of bibliometric studies in this particular field.
    Methods: For this study, we employed bibliometric analysis to outline focal points and patterns in scientific and clinical research. The collection of literature was gathered using the Web of Science Core Collection database. Bibliometric and visual analysis were conducted. Knowledge maps were generated using CiteSpace and VOSviewer software.
    Results and conclusions: With the deepening of the research, therapeutic angiogenesis will become a treatment direction for acute myocardial infarction in the future.
    Keywords:  CAD; VOSviewer; acute myocardial infarction; angiogenesis; bibliometric
    DOI:  https://doi.org/10.3389/fcvm.2025.1426583
  59. J Exp Orthop. 2025 Jan;12(1): e70183
    The 50 most cited studies on trochleoplasty.
    Alexander Pfarrmaier, Romed P Vieider, Rodrigo Sanchez, Lukas N Muench, Lukas Willinger, Sebastian Siebenlist, Armin Runer.
       Purpose: This study aimed to analyse the 50 most cited publications on trochleoplasty (TP), examine their bibliographic parameters and evaluate the correlations between citation count, methodological quality and other factors.
    Methods: In a comprehensive literature search on the Web of Science, the 50 most cited studies on TP were identified. These studies were then evaluated according to their bibliographic parameters, level of evidence (LOE), citation counts, the Modified Coleman Methodological Score (MCMS), the Methodological Index for Non‑Randomised Studies (MINORS) and the Radiologic Methodology and Quality Scale (MQCSRE).
    Results: Of the top 50 list, 15 articles (30%) were published in the journal 'Knee Surgery Sports Traumatology Arthroscopy' (KSSTA). A total of 39 studies were published by institutes from Europe (78%), with France and Switzerland being represented 10 times each. Of eight different study types, case series (n = 25, 50%) and systematic reviews (n = 16, 32%) were the most prevalent. LOE included Level III (n = 1, 2%), Level IV (n = 41, 82%) and Level V studies (n = 8, 16%) studies. The total citation count amounted to 2481 citations, ranging from 10 to 187 (mean 49.6 ± 41.5) and showed a mean citation density of 5.1 ± 2.6. Quality scores were 60.8 ± 9.8 for MCMS (n = 26), 11.1 ± 2.9 for MINORS (n = 26) and 22.5 ± 2.1 for MQCSRE (n = 25), respectively. High citation counts did not statistically correlate with higher study quality scores (p > 0.05).
    Conclusion: Overall, there is growing scientific interest in TP as a treatment option for patients suffering from patellofemoral instability despite the lack of articles with a high LOE and methodological quality. This review of the top 50 most cited studies provides orthopaedic surgeons with a resource to assess the most impactful academic contributions to TP.
    Level of Evidence: Level IV.
    Keywords:  bibliographic analysis; patella; patellofemoral Instability; qualitative analysis; trochleaplasty; trochleoplasty
    DOI:  https://doi.org/10.1002/jeo2.70183
  60. Arthroscopy. 2025 Feb 24. pii: S0749-8063(25)00139-2. [Epub ahead of print]
    Artificial Intelligence Research Receives Similar Online Attention but Increased Citation Rates Compared to Control Articles.
    Evan M Polce, Cory J Call, Tessa C Griffin, Kyle N Kunze, Eric J Cotter, Brian F Grogan.
       PURPOSE: To compare the social media attention and citation rates between artificial intelligence (AI) and non-AI research in the orthopedic surgery literature.
    METHODS: Research articles using AI for the purpose of statistical analysis or evaluating the use of AI for specific clinical use cases were included. Articles selected from six high-impact orthopedic surgery journals between January 2018 and December 2023 were selected by month of publication in a 1:4 ratio within the same journal issue. The primary outcomes were the Altmetric Attention Score (AAS), an aggregate score comprising the degree of social media attention received on multiple online platforms (with higher scores indicating more attention), and cumulative citation rates. Multivariate linear regression analyses were conducted to assess the relationship between article type and 1) the AAS and 2) citation rate. A sub-analysis comparing the AAS and citation rates between articles using AI for the purpose of statistical analysis versus evaluating the use of AI for a specific clinical use case was performed.
    RESULTS: A total of 540 articles (AI-related articles: n = 110, 20.0%; control articles: n = 440, 80.0%) were included. The median AAS was 2.0 (interquartile range (IQR), 1 - 6) for AI-related articles and 1.0 (IQR, 0 - 5) for control articles (P = 0.006). However, when controlling for covariates in the multivariate regression, article type (AI vs controls) was not significantly associated with the AAS (ß: -1.1; P = 0.602). The median number of citations was significantly greater among AI-related articles (median [IQR]: 18 [9 - 35]) compared to control (median [IQR]: 9 [4 - 16]) articles (P < 0.001). Multivariate linear regression demonstrated an additional average increase of 13.4 citations (95% CI, 9.4 - 17.5; P < 0.001) per article for AI articles compared with controls.
    CONCLUSIONS: AI research published in six orthopedic surgery journals received approximately 13 additional citations on average compared to control articles published during a similar time. AI research did not receive greater social media attention on average after controlling for confounding variables.
    CLINICAL RELEVANCE: AI research in orthopedic surgery did not receive greater online attention but was cited more frequently relative to control articles. Given the increasing academic impact of these articles, orthopedic surgeons should become familiarized with AI research as clinical applications and AI solutions derived from such research become increasingly relevant and implemented within clinical practice workflows.
    DOI:  https://doi.org/10.1016/j.arthro.2025.02.018
  61. Zhonghua Kou Qiang Yi Xue Za Zhi. 2025 Feb 28. 60(3): 273-281
    [Research progress and frontier analysis of Laugier-Hunziker syndrome at home and abroad based on Citespace].
    M M Zhao, X Wang, W M Wang.
      Objective: Analyzing the overview, changing trends, hotspots, and frontiers of the rare oral disease Laugier-Hunziker syndrome (LHS) using bibliometrics. Methods: Search the CNKI (China National Knowledge Infrastructure) and Web of science core collection (WOSCC) databases. The time span for Chinese literature is from January 1992 to December 2023, and for English literature is from January 1986 to December 2023. Utilize Citespace software to conduct visualized analysis on various aspects of the literature, including publication volume, authors, countries, institutions, journals, and keywords. Results: This study included a total of 112 articles (25 in Chinese and 87 in English). The overall publication volume showed a fluctuating slow-growth trend. Foreign authors Lenane P and Powell F had the highest number of publications. The team from Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, had the most publications among domestic authors. In terms of international collaboration, the United States demonstrated the highest centrality, but the collaborative network worldwide appeared relatively loose. University College Dublin was the foreign institution with the highest publication volume, while Peking Union Medical College Hospital was the domestic institution with the most publications. The journal with the highest number of foreign publications was the Journal of The American Academy of Dermatology, and the journal with the most domestic publications was the Chinese Leprosy Skin Disease Journal. Research hotspots for Laugier-Hunziker syndrome included lesion sites and differential diagnosis, while the frontiers of research encompassed differential diagnosis, disease management, and clinical manifestations related to oral mucosa. Conclusions: Laugier-Hunziker syndrome research shows a focus on differential diagnosis and symptom management. Future studies should prioritize optimizing treatment methods and emphasizing psychological support, while promoting interdisciplinary collaboration and the integration of global research networks to improve clinical diagnostic and therapeutic outcomes.
    DOI:  https://doi.org/10.3760/cma.j.cn112144-20250116-00019
  62. Front Endocrinol (Lausanne). 2024 ;15 1441503
    The link between hyperuricemia and diabetes: insights from a quantitative analysis of scientific literature.
    Lili Ma, Jing Wang, Li Ma, Xian Min Wang.
       Background: Hyperuricemia (HUA) is a significant public health issue, ranking second only to diabetes in prevalence. While existing research demonstrates a robust correlation between these two conditions, the precise etiological mechanisms remain inadequately elucidated. This study utilized scientometric analysis to investigate the global association between HUA and diabetes.
    Methods: Data on HUA and diabetes were retrieved from the Web of Science Core Collection database, encompassing the period from its inception until September 30, 2024. Collaboration networks were examined using VOSviewer, cluster analysis was executed with CiteSpace, and systematic mapping was conducted using Bibliometrix.
    Results: By September 30, 2024, 1,464 studies indicated a consistent yearly increase in publications connecting HUA and diabetes despite some fluctuations. The lead authors were Richard J. Johnson, Miguel A. Lanaspa, and Masanari Kuwabara, with most contributors from China, the United States, and Japan. Key institutions include China Medical University, Shanghai Jiao Tong University, and Capital Medical University. The most published journal was Nutrition, Metabolism and Cardiovascular Diseases (CVDs), whereas the most cited journal was Diabetes Care. The reference network from 1987 to September 30, 2024, identified 19 clusters highlighting key research areas in HUA and diabetes, such as metabolic syndrome, uropathology, chronic kidney disease (CKD), and CVD. Exploring pathological mechanisms and pharmacological interventions linked to diabetes concomitant with HUA has emerged as a focal point of research and a burgeoning trend within the field.
    Conclusion: This study is the first scientometric analysis to synthesize research trends on HUA and diabetes, revealing molecular mechanisms and treatment strategies and providing theoretical insights for future clinical use.
    Keywords:  CiteSpace; VOSviewers; diabetes; hyperuricemia; scientometrics
    DOI:  https://doi.org/10.3389/fendo.2024.1441503
  63. J Fungi (Basel). 2025 Feb 04. pii: 117. [Epub ahead of print]11(2):
    Half-Century Scientometric Analysis: Unveiling the Excellence of Fungi as Biocontrol Agents and Biofertilisers.
    Ziqi Yuan, Qi Shen, Kefei Yu, Yan Liu, Huabao Zheng, Yanlai Yao, Baolei Jia.
      Reducing the use of chemical inputs is becoming a major challenge in developing sustainable agriculture. Fungi, known as biocontrol agents (BCAs) and biofertilisers, are crucial in scientific research and are celebrated for their efficacy, eco-friendliness, and multifaceted roles. In this study, a bibliometric analysis was conducted on 5349 articles related to fungi as BCAs and biofertilisers over the past half-century using the Web of Science Core Collection (WoSCC) database. The publications on fungi, such as BCAs and biofertilisers, have increased significantly over the last 20 years, with a maximum growth rate of 33.7%. The USA and China lead in this field. Keyword clustering analysis revealed that entomopathogenic fungi, including Hemiptera, Coleoptera, and Lepidoptera, can be used to manage plant pests. It also showed that fungi can be used as biofertilisers to promote plant growth. The analysis of research trends shows that Beauveria bassiana in biological control is highly significant. This study also showed that entomopathogenic fungi control plant pests by infiltrating the insect cuticles. Trichoderma spp. exert biocontrol effects by producing antibiotics. Arbuscular mycorrhizal fungi can trigger plant defence mechanisms by modulating secondary metabolite synthesis. This study contributes to the current knowledge of fungi as BCAs and biofertilisers and can guide future research.
    Keywords:  Trichoderma; arbuscular mycorrhizal fungi; bibliometric; biocontrol agents; biofertilisers; entomopathogenic fungi
    DOI:  https://doi.org/10.3390/jof11020117
  64. Int J Environ Res Public Health. 2025 Feb 12. pii: 264. [Epub ahead of print]22(2):
    Trends and Gaps in Colorectal Cancer Screening Research in the Arab World: A 16-Year Bibliometric Analysis (2007-2023).
    Noura Abbas, Laudy Chehade, Hawraa Tarhini, Zahi Abdul Sater, Ali Shamseddine.
      Colorectal cancer (CRC) is a significant public health concern, ranking third in incidence and second in mortality worldwide. Despite rising CRC incidence rates in the Arab world, understanding of trends and patterns in CRC screening research remains limited. This study addresses this gap through a bibliometric analysis of CRC screening research in the Arab world from 2007 to 2023. We conducted an extensive literature search in Web of Science and Scopus databases, analyzing 124 articles using the Bibliometrix Package in R. Our findings revealed a 16.5% annual growth in research output, with significant increases from 2014 onwards. Saudi Arabia led in scientific production, followed by Lebanon, Jordan, and Egypt, while Qatar had the highest country production when adjusted for population size. Disparities in research output relative to the CRC burden were evident, especially in lower-resource countries. Three regional clusters were identified: Saudi Arabia, with strong collaborations with Canada and Egypt; a second cluster including Lebanon, UAE, Jordan, Qatar, Iraq, and Oman; and a third cluster featuring Morocco, with significant collaboration with France. Thematic analysis showed a focus on CRC screening awareness, barriers, and adherence but a lack of studies on implementation strategies and cost-effectiveness. This analysis highlights significant trends and gaps in CRC screening research in the Arab world, underscoring the need for increased investment in CRC research and screening initiatives to improve outcomes in the region.
    Keywords:  Arab world; awareness; bibliometric; colonoscopy; colorectal cancer; country production; implementation; research gaps; screening
    DOI:  https://doi.org/10.3390/ijerph22020264
  65. Cir Esp (Engl Ed). 2025 Feb 21. pii: S2173-5077(25)00042-0. [Epub ahead of print]
    Bibliometric study of publications on pancreatic surgery carried out by spanish surgeons.
    Juan Jesús Rubio-García, Celia Villodre Tudela, Cándido Alcázar López, Silvia Carbonell Morote, Mariano Franco Campello, Paola Melgar Requena, Adrián Paredes Segura, J M Ramia Ángel.
       INTRODUCTION: Pancreatic pathology is a constant multidisciplinary challenge; It is a growing pathology and one of the main research topics. The aim of the study is to analyse the current situation in Spain in this field from a bibliometric perspective.
    METHODS: We conducted a systematic review following the PRISMA guidelines, utilizing the PubMed/Medline and sCIELO databases. The search strategy included the terms: '(pancreas OR pancreatectomy) AND surgery AND Spain.' The publication period spanned from January 2019 to March 2024. Our inclusion criteria specified any article, in any language, where at least one participant was a surgeon in a hospital in Spain, and that had an impact factor (IF).
    RESULTS: The search yielded 522 citations, of which 133 articles were selected after applying our inclusion and exclusion criteria. The trend over time indicates a progressive increase in publications. Notably, 36.1% of the articles were published in Q1 journals, while 35.3% appeared in Q3 journals, with a mean impact factor of 4.07. Spanish authors accounted for 63.2% of publications. The most common types of articles were retrospective studies, case reports, and systematic reviews, with 35.3% being international multicenter studies. Key topics addressed included minimally invasive approaches, surgical techniques, and postoperative management. The journal Cirugía Española (Q3) published the highest number of papers (20.3%).
    CONCLUSION: In recent years, Spain has experienced a significant increase in publications related to pancreatic surgery. However, when compared to leading countries in this field, the number of randomized clinical trials remains low.
    Keywords:  Bibliometry; Bibliometría; Cirugía; Manuscripts; Pancreas; Publicaciones; Páncreas; Surgery
    DOI:  https://doi.org/10.1016/j.cireng.2024.12.015
  66. Front Microbiol. 2025 ;16 1466419
    HIV and the gut microbiome: future research hotspots and trends.
    Zhen Wu, Zhan-Peng Xie, Xin-Xin Cui, Xiang-Bin Sun, Fang-Yi Zhao, Nuo Wang, Yu Li, Haixia Wang, Li Zhang, Jing Shen, Fulei Chen, Haogang Sun, Jia He.
       Background: The use of highly active antiretroviral therapy has transformed AIDS into a chronic infectious disease, but issues of chronic inflammation and immune system activation persist. Modulating the gut microbiome of patients may improve this situation, yet the specific association mechanisms between HIV and the gut microbiome remain unclear. This study aims to explore the research hotspots and trends of the HIV and the gut microbiome, providing direction for future research.
    Methods: We conducted a search of the Web of Science Core Collection database up to April 30, 2024 to retrieve articles related to the relationship between the HIV and the gut microbiome. The scientific achievements and research frontiers in this field were analyzed using CiteSpace, VOSviewer, and Bibliometrix statistical software.
    Results: As of April 30, 2024, a total of 379 articles met the inclusion criteria. The number of publications in this field peaked in 2023, and the number of articles published after 2020 declined. The country with the highest number of publications was the United States (184 articles), and the institution with the most publications was the University of Colorado (USA) (21 articles). The author with the most publications was Routy Jean-Pierre (Canada) (14 articles). High-frequency keywords, aside from the key terms, included "HIV," "inflammation," "immune activation," "gut microbiota," and "translocation." Keyword burst results indicated that short-chain fatty acids, T cells and obesity might become the focus of future research.
    Conclusion: The research hotspots in this field should prioritize examining the role of the primary gut microbiome metabolite, short-chain fatty acids, in reducing immune system activation and inflammation. Another emerging area of interest could be the investigation into the annual increase in obesity rates within this field. Furthermore, understanding the metabolic mechanisms of short-chain fatty acids in T cells is essential. Additionally, multi-omics analysis holds potential.
    Keywords:  HIV/AIDS; T cells; bibliometrics; gut microbiome; obesity; short-chain fatty acids
    DOI:  https://doi.org/10.3389/fmicb.2025.1466419
  67. Brain Res Bull. 2025 Feb 25. pii: S0361-9230(25)00089-9. [Epub ahead of print] 111277
    Unveiling causal relationships between tobacco use phenotypes and neuroimaging: Insights from bidirectional Mendelian randomization and bibliometric analysis.
    ZhaoTao Zhang, LongTao Yang, HuaFang Guan, JiMan Shao, ZhiJian Chen, XinLan Xiao, XiaoYong Wu.
      Smoking is considered the most common addictive behavior worldwide. However, it is not systematically investigated whether there are bidirectional causal associations between tobacco use and neuroimaging, which might provide potential neural biomarkers or therapeutic neuro-targets for tobacco abuse or rehabilitation. In this study, using Mendelian randomization (MR), we explored both forward and reverse causal relationships between 4 tobacco use phenotypes (including Cigarettes per day, Smoking initiation, Age of initiation and Smoking cessation) and 209 neuroimaging features involving brain function and structure. Besides, we conducted a bibliometric analysis to find corresponding global trends of knowledge and specialized research areas. After Bonferroni correction, positive causal associations between cerebral global functional connectivity (FC) and smoking cessation, as well as between age of initiation and default mode network (DMN) structural connectivity (SC) were revealed; there were negative causal associations between mean diffusivity of left medial lemniscus and cigarette per day. Up to now, we also reveal that functional neuroimaging especially FC dominated smoking research field. Therefore, the discovery of causal relationships between smoking-related phenotypes and multi-modal cerebral alterations will promote a comprehensive understanding of tobacco addiction from cerebral function and structure perspective, facilitating the progression of personal treatment and risk prediction.
    Keywords:  Bibliometric analysis; Functional neuroimaging; Mendelian randomization; Structural neuroimaging; Tobacco use
    DOI:  https://doi.org/10.1016/j.brainresbull.2025.111277
  68. J Surg Res. 2025 Feb 21. pii: S0022-4804(25)00027-7. [Epub ahead of print]307 62-69
    Quantitative and Qualitative Analysis of Clinical Trial Acronyms From Surgical Journals.
    Hong-Min Ahn, Hyeon Woo Shin, Heung-Kwon Oh, Yoon Ju Jung, Anuj Naresh Singhi, Min Hyeong Jo, Mi Jeong Choi, Tae-Gyun Lee, Hye Rim Shin, Duck-Woo Kim, Sung-Bum Kang.
       INTRODUCTION: Acronyms, the short form of a word or phrase, are commonly used in medical research to identify studies. However, their usage and quality assessment in surgical journals are unclear. This study aimed to determine the impact of identifying acronyms for clinical studies on the number of citations by comparing studies published in surgical and medical journals.
    METHODS: Articles were screened from five highly cited journals (Annals of Surgery, British Journal of Surgery, JAMA Surgery, Journal of the American College of Surgeons, and New England Journal of Medicine, alphabetically). The correlation between acronym use and number of citations was analyzed. In addition, the characteristics and quality of acronyms, in terms of lettering and wording scores, used to identify studies were evaluated for acronymous trials using a developed and self-validated scoring tool.
    RESULTS: Of 291 eligible articles, 167 (57.4%) were acronymous studies. Although 70.5% (122/173) of articles in general medical journals used identifying acronyms, only 38.1% (45/118) used them in surgical journals (P < 0.001). The median number of citations was higher for acronymous studies (212 versus 53; P < 0.001). Multivariable analysis revealed that acronymous studies had a 2.5-fold higher possibility of being a highly cited (odds ratio 2.514, P = 0.004). The average quality scores of the acronyms were similar for surgical and general medical journals (5.1 ± 1.7 versus 5.1 ± 1.6, P = 0.949). Surgical journals had lower lettering (2.20 ± 1.14 versus 3.02 ± 1.04, P < 0.001) but higher wording scores (2.89 ± 1.01 versus 2.09 ± 1.14, P < 0.001) than general medical journals.
    CONCLUSIONS: Given the publicity effect of acronyms, a memorable acronym devised using the first or continuous letters for surgical studies may help recognize their clinical impact.
    Keywords:  Acronym; Clinical research; Medicine; Surgery
    DOI:  https://doi.org/10.1016/j.jss.2025.01.009
  69. Ageing Res Rev. 2025 Feb 22. pii: S1568-1637(25)00038-8. [Epub ahead of print]106 102692
    From text to insight: A natural language processing-based analysis of burst and research trends in HER2-low breast cancer patients.
    Muyao Li, Ang Zheng, Mingjie Song, Feng Jin, Mengyang Pang, Yuchong Zhang, Ying Wu, Xin Li, Mingfang Zhao, Zhi Li.
      With the intensification of population aging, the proportion of elderly breast cancer patients is continuously increasing, among which those with low HER2 expression account for approximately 45 %-55 % of all cases within traditional HER2-negative breast cancer. Concurrently, the significant therapeutic effect of T-DXd on patients with HER2-low tumors has brought this group into the public spotlight. Since the clinical approval of T-DXd in 2019, there has been a significant vertical surge in the volume of publications within this domain. We analyzed 512 articles on HER2-low breast cancer from the Web of Science Core Collection using bibliometrics, topic modeling, and knowledge graph techniques to summarize the current state and trends of research in this domain. Research efforts are particularly concentrated in the United States and China. Our analysis revealed six main research directions: HER2 detection, omics and clinical biomarkers, basic and translational research, neoadjuvant therapy and prognosis, progress of ADC drugs and clinical trials. To enhance the therapeutic efficacy and safety of antibodydrug conjugates (ADCs), researchers are actively exploring potential drug candidates other than T-DXd, with numerous ADC drugs emerging in clinical practice and trials. By incorporating emerging treatment strategies such as immunotherapy and employing circulating tumor cell (CTC) detection techniques, progress has been made toward improving the prognosis of patients with low HER2 expression. We believe that these research efforts hold promise as compelling evidence that HER2-low breast cancer may constitute a distinct and independent subtype.
    Keywords:  HER2-low breast cancer; T-DXd; antibodydrug conjugate (ADC); bibliometric analysis; visual analysis
    DOI:  https://doi.org/10.1016/j.arr.2025.102692
  70. J Appl Behav Anal. 2025 Feb 28.
    The editorial boards of behavior-analytic journals: An analysis of geographic distribution and presumed gender.
    Joey Ryan, Hugo Curiel, Kwangmin Lee.
      The geographic distribution and gender of authors who have published in behavior-analytic journals have been analyzed at different points. Yet little is known about the geographic and gender diversity of editorial board members who have served on prominent behavior-analytic journals. We analyzed the regional and gender distribution of editorial board members-editors in chief, associate editors, and members of editorial boards-serving at the Journal of the Experimental Analysis of Behavior, Journal of Applied Behavior Analysis, and Perspectives on Behavior Science from 2000 to 2023. Our analysis showed that (a) the journals have been led primarily by editors with U.S. affiliations, (b) women have been underrepresented at the editor-in-chief and associate-editor levels, and (c) the gender gap has steadily decreased among editorial board members in recent years. We discuss the importance of diversity in the editorial leadership of academic journals and offer suggestions for expediting change.
    Keywords:  editorial boards; gender; gender diversity; geographic distribution
    DOI:  https://doi.org/10.1002/jaba.2939
  71. Int J Environ Res Public Health. 2025 Jan 22. pii: 146. [Epub ahead of print]22(2):
    Global Perspectives on Obesity and Being Overweight: A Bibliometric Analysis in Relation to Sustainable Development Goals.
    Natália Ueda Yamaguchi, Letícia de Almeida, Rúbia Carvalho Gomes Corrêa, Rute Grossi Milani, Mirian Ueda Yamaguchi.
      Obesity and being overweight are significant risk factors for diseases and disabilities, making it crucial to address malnutrition in all its forms to ensure health and well-being for all, as well as to achieve sustainable development. This study conducted a bibliometric analysis of research on obesity in relation to Sustainable Development Goals (SDGs) using data from the Web of Science database from 2015 to 2024 and the VOSviewer software. The findings revealed that while research on obesity and SDGs has grown slowly, SDG 3 (Good Health and Well-Being) is predominant in the literature. This study highlighted the fragmentation of research due to the complex, multifactorial nature of obesity, emphasizing the need for a more holistic approach. Furthermore, international collaborations were found to be vital for advancing research and formulating effective public policies. This analysis also identified gaps in the research related to several SDGs, including education (SDG 4), affordable and clean energy (SDG 7), and partnerships (SDG 17), suggesting the need for a broader, more holistic approach. Additionally, emerging research related to SDG 11 (Sustainable Cities and Communities) underscores the importance of urban environments in tackling obesity. In conclusion, future research should adopt an interdisciplinary approach to address these gaps and contribute to advancing the 2030 Agenda.
    Keywords:  SDG; agenda 2030; bibliometrics; health promotion; nutrition
    DOI:  https://doi.org/10.3390/ijerph22020146
  72. Heliyon. 2025 Feb 15. 11(3): e42471
    Self-citation pattern among world's top 2 % of the scientists.
    Berun A Abdalla, Ayman M Mustafa, Fattah H Fattah, Fahmi H Kakamad, Sami S Omar, Ameer M Salih, Aso S Muhialdeen, Jaafar Omer Ahmed, Rawa Bapir, Shvan H Mohammed, Karokh K Mohammed, Hiwa O Baba, Sasan M Ahmed, Shevan M Mustafa, Kayhan A Najar.
      Although self-citation is a common practice among scholars, its impact and significance remain under scrutiny within the academic community. The current study aimed to provide a detailed analysis and ranking of the top 2 % scientists on self-citation, ranked by Stanford University researchers. Data extraction and organisation were performed between January and February 2024. Self-citation percentages were collected for authors belonging to 20 fields and 174 subfields using Excel spreadsheets. Entities were categorised into quartiles based on their self-citation percentages and rankings were assigned accordingly. Comparative analyses were conducted to assess the impact of self-citations on overall rankings. The study focused on data published by a group of researchers from Stanford University regarding the top 2 % of researchers, analysing the career-long records of 204,643 scholars and 210,198 scholars for the most recent year, 2022. Notably, in the single-year analysis, among the top 20 countries, approximately eight (40 %) exhibited self-citation percentages exceeding the average of 25.96 %. The self-citation percentages ranged from 4.47 % in Economics and Business to 20.88 % in Physics and Astronomy. Regarding career-long analysis, the percentage of self-citations ranged from 22.84 % in Poland to 41.31 % in Armenia, with significant drop in rankings among most entities when self-citations were excluded. These findings highlight the dramatic impact of self-citation exclusion on the rankings of the top 2 % of the researchers, underscoring the critical importance of accounting for self-citation in ranking assessments.
    Keywords:  Citation analysis; Impact factor; Scientific publishing; Self-citation
    DOI:  https://doi.org/10.1016/j.heliyon.2025.e42471
  73. Ren Fail. 2025 Dec;47(1): 2460747
    Comment on 'the relationship between kidney disease and mitochondria: a bibliometric study'.
    Guozhen Wang, Wenwen Mu, Tianxing Zhang.
      
    DOI:  https://doi.org/10.1080/0886022X.2025.2460747
  74. Front Res Metr Anal. 2025 ;10 1504937
    A worldwide itinerary of research ethics in science for a better social responsibility and justice: a bibliometric analysis and review.
    Ingrid Sonya Mawussi Adjovi.
      This study provides a comprehensive overview of research ethics in science using an approach that combine bibliometric analysis and systematic review. The importance of ethical conduct in scientific research to maintain integrity, credibility, and societal relevance has been highlighted. The findings revealed a growing awareness of ethical issues, as evidenced by the development of numerous guidelines, codes of conduct, and oversight institutions. However, significant challenges persist, including the lack of standardized approaches for detecting misconduct, limited understanding of the factors contributing to unethical behavior, and unclear definitions of ethical violations. To address these issues, this study recommends promoting transparency and data sharing, enhancing education, and training programs, establishing robust mechanisms to identify and address misconduct, and encouraging collaborative research and open science practices. This study emphasizes the need for a collaborative approach to restore public confidence in science, protect its positive impact, and effectively address global challenges, while upholding the principles of social responsibility and justice. This comprehensive approach is crucial for maintaining research credibility, conserving resources, and safeguarding both the research participants and the public.
    Keywords:  bibliometric mapping; community involvement; ethics in research; review; social equity; university
    DOI:  https://doi.org/10.3389/frma.2025.1504937
  75. ANZ J Surg. 2025 Feb 26.
    A snapshot of female representation in the presentation of orthopaedic research, an Australian perspective.
    Kathlyn Andersen, Karoline Kant.
       BACKGROUND: The gender disparity in the field of orthopaedic surgery is globally recognized. In Australia, the percentage of female orthopaedic surgeons is currently 5.5% while the percentage of trainees is 18.9%. The Australian Orthopaedic Association's annual scientific meeting (ASM) program represents one way to visualize gender diversity within orthopaedics. This study aims to quantify the representation of women in national orthopaedic research presentations.
    METHODS: This is a retrospective cohort study of ASM presentations from 2021 to 2023. Presenter information was obtained from available published scientific programs. Presenter gender was classified by first name as a binary construct using a combination of biography, internet, registration, and the website Gender API (https://gender-api.com). The proportion of female versus male presenters and moderators was determined and gender trends between topics was analysed.
    RESULTS: Of 936 research presentations given across the 3 years, 15.9% were given by females. The topic areas with the highest percentage of female speakers were paediatrics (42.1%) and hand (25.0%), with the lowest percentage in shoulder and elbow (10.3%) and spine (3.8%). The proportion of female session moderators averaged 20.2%. There was no difference in number of presentations given or sessions moderated per person with regard to gender.
    CONCLUSIONS: This is the first paper to investigate gender disparity in the presentation of orthopaedic research in Australia. The percentage of female participation is low, however remains in proportion with female representation within the speciality. Increasing numbers of visible female presenters will serve to improve the gender landscape within orthopaedics.
    Keywords:  Australia; female; orthopaedic surgeons; orthopaedics; surgeons
    DOI:  https://doi.org/10.1111/ans.70020
  76. Medicine (Baltimore). 2025 Feb 21. 104(8): e41594
    Examining the frequency of artificial intelligence generated content in anesthesiology and intensive care journal publications: A cross sectional study.
    Selin Erel, Ozge Erkocak Arabaci, Hasan Kutluk Pampal.
      The emergence of artificial intelligence (AI)-based linguistic models has revolutionized academic writing, prompting concerns about integrity. In response, AI-powered text authenticity detectors have been developed. This study examines AI tool usage in anesthesiology and intensive care journals. 1268 articles from 86 journals in "Anesthesiology" and "Anesthesiology and Intensive Care" were analyzed using Copyleaks and ZeroGPT. English abstracts published between April 18 and May 18, 2023, were scrutinized. ZeroGPT and Copyleaks found average AI usage at 25.1% ± 27.5 and 10.5% ± 15.9, respectively. 16.8% of articles were "human-written," while 83.2% were "AI-assisted". AI assistance correlated positively with abstract length and was more common among nonnative English speakers (P < .001). It was also prevalent in high-impact and science citation index-indexed journals (P < .01; P < .001). This study underscores the widespread adoption of AI tools in academic writing, particularly among nonnative English authors and in high-impact journals, emphasizing the need for improved detection mechanisms and regulatory guidelines.
    DOI:  https://doi.org/10.1097/MD.0000000000041594
  77. OTO Open. 2025 Jan-Mar;9(1):9(1): e70092
    Factors Associated With Gender Distribution in Academic Rhinology.
    Alison J Yu, Stephanie Wong, Kevin Herrera, Daniel Palmieri, Bozena Wrobel, Tamara Chambers, Nadia Chan.
       Objective: Women have been underrepresented in academic medicine and surgical fields. This study aimed to describe the gender distribution in academic rhinology and investigate otolaryngology departmental factors associated with female rhinologists representation.
    Study design: Cross-sectional study.
    Setting: American Medical Association (AMA) FREIDA database, American Rhinologic Society database, and online search.
    Methods: We identified fellowship-trained rhinologists from institutional searches of residency programs identified from the AMA FREIDA database. Demographic and academic data of each rhinologist were extracted from online search. Departmental characteristics were obtained from the FREIDA database and institutional websites. The associations between female rhinologists representation and departmental factors were assessed using logistic regression analyses.
    Results: Among 224 fellowship-trained rhinologists, female comprised 26.8%. There were more female assistant professors (55.0% vs 39.6%) and fewer full professors (10.0% vs. 24.4%) than their male counterparts (P = .046). The mean H index was lower for female than male rhinologists among those over 5 years in practice (20.5 vs 33.0, P = .029). In the multivariate analysis, female rhinologists were more likely to be found in departments with greater proportions of female faculty (adjusted odds ratio 1.08 [95% confidence interval 1.04-1.12], P < .001).
    Conclusion: The proportion of female rhinologists decreased significantly as they advanced through academic rank. The main driver for female rhinologists representation is the increased number of female faculty in the department. There should be increased efforts to promote female mentorship and women in leadership positions.
    Keywords:  academic otolaryngology; female representation; gender diversity; gender equality; rhinology workforce
    DOI:  https://doi.org/10.1002/oto2.70092
  78. J Gastroenterol Hepatol. 2025 Feb 26.
    Gender Differences in the Authorship of Gastroenterology Clinical Practice Guidelines.
    Sandy Ng, Samantha Novotny, Garvita Sharma, Pragati Shrestha, Naomi Nguyen, Sabrina Mohsin, Dawei Wu, Daanyaal Kumar, Rasagnya Kota, Kunal Shah, George-Abraam Tawfik, Cynthia Edimo, Zhi Jian Wu, Olga Aroniadis.
       BACKGROUND AND AIM: Women are underrepresented in gastroenterology (GI), and few studies have evaluated gender differences in the authorship of GI clinical practice guidelines. This study aimed to assess gender disparities in the authorship of GI guidelines and their cited articles over time.
    METHODS: We reviewed luminal GI guidelines from three major GI societies to compare authorship of current guidelines (defined as published from 2019 to 2022) to their retired guidelines (defined as the previous guideline replaced by the current guideline). Several characteristics of the author and article including gender, faculty rank, study type, and strength of recommendation supported by the cited article were collected to evaluate factors associated with female authorship.
    RESULTS: We reviewed 13 current guidelines, 12 retired guidelines, and 4328 cited articles. There was no significant change in female authorship of guidelines from 2010 to 2022. Proportions of female first (p-value < 0.0001) and senior (p-value < 0.0001) authors of cited articles increased over time. Women were less often first authors of cited randomized control trials, systematic reviews, and meta-analyses than observational studies (35% vs. 65%, p < 0.0001). Cited articles that supported a "strong" guideline recommendation were less often first-authored (19% vs. 81%, p = 0.003) and senior-authored (10% vs. 90%, p = 0.006) by women.
    CONCLUSIONS: Female authorship increased over time, but a gender disparity remains. Female authors less commonly authored higher level of evidence studies. Further studies are needed to assess if the proportional increase in female authorship is due to a small subset of prolific authors or representative of the number of women practicing in gastroenterology.
    Keywords:  authorship; disparity; gastroenterology; gender; guidelines
    DOI:  https://doi.org/10.1111/jgh.16913
  79. J Safety Res. 2024 Dec;pii: S0022-4375(24)00096-3. [Epub ahead of print]91 1-19
    Psychological safety and psychosocial safety climate in workplace: A bibliometric analysis and systematic review towards a research agenda.
    Rebecca Kechen Dong, Xiaomei Li, 'Banjo' Roxas Hernan.
       INTRODUCTION: Research on workplace safety has seen significant growth in academic and industry-focused literature over the past 20 years. However, the extant literature on workplace safety tends to focus on safety outcomes of physical accidents and injuries while relegating its conceptual and theoretical development to the background. Psychological safety and psychosocial safety climate in the workplace are essential to workers' health and safety. These concepts are crucial in enabling job satisfaction, work engagement, and performance productivity. Progressing the literature on this subject is necessary to keep abreast with the changing dynamics of the post-COVID challenges, such as working from home, isolation, and stress from AI, among others. A significant gap in the extant literature burrows in the lack of conceptual clarity of workplace safety from a psychological perspective and the poor understanding of its substantive effects on organizations. Hence, re-examining workplace safety's conceptual and theoretical foundations from a psychological lens offers a more nuanced understanding of its potential to contribute to employee well-being and organizational resilience, pursuing a better work-life safe and more comfortable working environment.
    METHOD: This study: (a) synthesizes the theoretical propositions and empirical findings from 990 research articles published between 2000 and 2023 to map the existing body of knowledge about psychological safety and psychosocial safety climate, including their theoretical underpinnings and mechanisms, to offer a state-of-the-art overview of the scope of workplace occupational health and safety research from a psychological perspective; (b) applied a data-based research design adhering to PRISMA; (c) compiled descriptive synthesis and textual narrative syntheses through bibliometric analysis and a systematic literature review; and (d) opens the black box of workplace safety research by presenting significant findings to inform future conceptual, theoretical, and methodological research as well as the practice of workplace safety through the lens of psychology.
    RESULTS: This study's findings further offer managerial implications to workplace safety policy-making and human resource management practices to enhance employees' psychological safety and eliminate workplace psychosocial hazards.
    Keywords:  Bibliometric analysis; Psychological safety; Psychosocial safety climate; Systematic review
    DOI:  https://doi.org/10.1016/j.jsr.2024.08.001
  80. Plants (Basel). 2025 Feb 14. pii: 581. [Epub ahead of print]14(4):
    Recent Advancements and Trends in Postharvest Application of Edible Coatings on Bananas: A Comprehensive Review.
    Mawande H Shinga, Yardjouma Silue, Olaniyi A Fawole.
      Bananas (Musa spp.) are among the most widely consumed fruits globally, yet their high perishability and short shelf-life pose significant challenges to the postharvest industry. To address this, edible coatings have been extensively studied for their ability to preserve the physical, microbiological, and sensory qualities of bananas. Among various types of edible coatings, polysaccharide-based coatings, particularly chitosan, have emerged as the most effective. The dipping method is predominantly employed for their application, surpassing spraying and brushing techniques. This review integrates insights from bibliometric analysis using Scopus, revealing that research on edible coatings for bananas began in 2009, with 45 journals contributing to the field. Key trends, including publication growth, author contributions, and geographical focus, are explored through VOS-viewer analysis. Mechanistically, edible coatings enhance postharvest banana quality by limiting gaseous exchange, reducing water loss, and preventing lipid migration. Performance is further improved by incorporating active ingredients such as antioxidants, antimicrobials, and plasticizers. Despite their benefits over synthetic chemicals, the commercial adoption of edible coatings faces limitations, related to scalability and practicality. This review highlights these challenges while proposing future directions for advancing edible coating technologies for banana preservation.
    Keywords:  active ingredient; banana; bibliometric analysis; edible coatings; mode of action; ripening
    DOI:  https://doi.org/10.3390/plants14040581
  81. J Hand Surg Glob Online. 2025 Jan;7(1): 66-71
    The Impact of Social Media for Hand Surgeons: A Prevalence and Correlation Study With Online and Academic Reputations.
    Sameer R Khawaja, Krishna N Chopra, Musab Gulzar, Ozair R Khawaja, Shammah E Udoudo, Joseph G Monir, Michael B Gottschalk, Adrian L Huang, Nina Suh, Eric R Wagner.
       Purpose: This study examines the influence of social media use among orthopedic and plastic-trained hand surgeons on patient-reported ratings online and academic productivity.
    Methods: The American Society of Surgery of the Hand directory was queried for actively practicing orthopedic and plastic surgeons with a hand surgery fellowship. Each name was searched on various social media platforms. Average ratings, number of reviews, and number of comments were collected from Healthgrades, Google reviews, and Vitals. H-index was searched on Scopus. A summated social media presence score was calculated to identify the top 20% of social media users in each cohort.
    Results: A total of 97 orthopedic and 102 plastic surgeons were included. Overall, plastic surgeons were more active on social media compared to orthopedic surgeons. There was a positive association between having active profiles and Healthgrades ratings. When looking within the subgroups, the top 20% of social media orthopedic users were found to have a significantly higher mean Healthgrades rating and a mean number of comments than the rest of the cohort. On Vitals, the top 20% of social media users had higher mean ratings compared to the remaining 80%. The top 20% of plastics social media users had a significantly higher average Healthgrades rating compared to the rest of the plastics group. On Google reviews, the top 20% also had higher mean ratings, as well as mean number of ratings, compared to the rest of the cohort. Plastic surgeons with a Twitter/X account had a significantly higher h-index than plastic surgeons without a Twitter/X account (14.5 vs 9.2, P < .05).
    Conclusions: Social media involvement is positively associated with surgeon ratings and the number of reviews and comments on physician rating websites. Using web-based marketing tools is still rare in hand surgery, especially among orthopedic surgeons.
    Type of study/level of evidence: Economic/decision analysis IV.
    Keywords:  H-index; Hand surgery; Orthopedic surgery; Plastic surgery; Social media
    DOI:  https://doi.org/10.1016/j.jhsg.2024.11.001
  82. Int Endod J. 2025 Feb 27.
    Gender diversity in endodontics: Women's representation at recent biennial meetings.
    Ayse Karadayi, Fatima Betul Basturk.
       AIM: Leadership opportunities within professional fields often include invitations to speak at major organizational meetings. However, the representation of speakers from underrepresented groups at annual scientific meetings of endodontic organizations has yet to be documented. This observational study aimed to evaluate the percentage of women invited to speak at selected endodontic organization meetings.
    METHODOLOGY: The number of male and female keynote or invited speakers at the European Society of Endodontology (ESE), Asian Pacific Endodontic Confederation (APEC), and International Federation of Endodontic Associations (IFEA) conferences from 2013 to 2023 were recorded. A chi-square test was conducted to assess differences in the percentage of women speakers over time and among the three organizations.
    RESULTS: A total of 714 keynote and invited speakers from the scientific meetings of the three endodontic organizations between 2013 and 2023 met the inclusion criteria. Of these, 601 (84.17%) were men, and 113 (15.83%) were women, reflecting a significant gender disparity (p < 0.001). No significant differences were observed between the organizations, nor was there a significant change in the number of women speakers over time.
    CONCLUSIONS: Regardless of the organization or the timeframe, the number of women speakers at scientific meetings remains consistently lower than that of men, with no significant change observed over the past decade.
    Keywords:  conferences; endodontics; gender; representation; women
    DOI:  https://doi.org/10.1111/iej.14212
  83. Multidiscip Respir Med. 2025 Feb 28. 20
    Integrating narrative and bibliometric approaches to examine factors and impacts of tuberculosis treatment non-compliance.
    Agus Santosa, Neti Juniarti, Tuti Pahria, Raini Diah Susanti.
       BACKGROUND: Tuberculosis (TB) treatment non-compliance remains a significant global public health issue, undermining disease control efforts and leading to adverse clinical and epidemiological outcomes. While considerable research has explored this issue, gaps remain in understanding the multifactorial influences on non-compliance, particularly its key factors and impacts, as well as the interconnections that exacerbate these challenges. This study integrates narrative and bibliometric approaches to critically synthesize and visualize factors contributing to TB treatment non-compliance and its impacts. By addressing research gaps, this study aims to provide a comprehensive framework for understanding the multifactorial challenges and proposing evidence-informed strategies to address clinical and epidemiological issues.
    METHODS: A systematic search of Scopus, EBSCO (Medline), ScienceDirect, and PubMed databases identified empirical studies published up to December 2024. Thematic synthesis categorized factors into overarching themes, while bibliometric analysis using VOSviewer software visualized factors and their interconnections.
    RESULTS: The review identified key factors such as poor tuberculosis knowledge, stigma, side effects, and economic constraints, interacting with demographic, psychological, and systemic barriers. Network visualization highlighted the interconnections among these factors, illustrating how they compound to exacerbate non-compliance. Clinical and epidemiological impacts include MDR/XDR-TB, prolonged treatment, and community transmission.
    CONCLUSIONS: TB treatment non-compliance arises from a complex interplay of individual, socio-economic, and healthcare-related factors. This review emphasizes the importance of integrated narrative and bibliometric approaches to develop context-specific strategies for improving adherence, reducing the global TB burden, and guiding future research and policy.
    DOI:  https://doi.org/10.5826/mrm.2025.1016
  84. Biology (Basel). 2025 Jan 26. pii: 129. [Epub ahead of print]14(2):
    Advances in Huntington's Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review.
    Sarah Aqel, Jamil Ahmad, Iman Saleh, Aseela Fathima, Asmaa A Al Thani, Wael M Y Mohamed, Abdullah A Shaito.
      Neurodegenerative disorders (NDs) cause progressive neuronal loss and are a significant public health concern, with NDs projected to become the second leading global cause of death within two decades. Huntington's disease (HD) is a rare, progressive ND caused by an autosomal-dominant mutation in the huntingtin (HTT) gene, leading to severe neuronal loss in the brain and resulting in debilitating motor, cognitive, and psychiatric symptoms. Given the complex pathology of HD, biomarkers are essential for performing early diagnosis, monitoring disease progression, and evaluating treatment efficacy. However, the identification of consistent HD biomarkers is challenging due to the prolonged premanifest HD stage, HD's heterogeneous presentation, and its multiple underlying biological pathways. This study involves a 10-year bibliometric analysis of HD biomarker research, revealing key research trends and gaps. The study also features a comprehensive literature review of emerging HD biomarkers, concluding the need for better stratification of HD patients and well-designed longitudinal studies to validate HD biomarkers. Promising candidate wet HD biomarkers- including neurofilament light chain protein (NfL), microRNAs, the mutant HTT protein, and specific metabolic and inflammatory markers- are discussed, with emphasis on their potential utility in the premanifest HD stage. Additionally, biomarkers reflecting brain structural deficits and motor or behavioral impairments, such as neurophysiological (e.g., motor tapping, speech, EEG, and event-related potentials) and imaging (e.g., MRI, PET, and diffusion tensor imaging) biomarkers, are evaluated. The findings underscore that the discovery and validation of reliable HD biomarkers urgently require improved patient stratification and well-designed longitudinal studies. Reliable biomarkers, particularly in the premanifest HD stage, are crucial for optimizing HD clinical management strategies, enabling personalized treatment approaches, and advancing clinical trials of HD-modifying therapies.
    Keywords:  Huntington’s disease; biomarkers; diffusion tensor imaging (DTI); microRNAs (miRNAs); neurodegenerative disorders; neurofilament light chain (NfL); preHD; premanifest HD; rare diseases
    DOI:  https://doi.org/10.3390/biology14020129
  85. One Health Outlook. 2025 Feb 25. 7(1): 12
    The role of climatic changes in the emergence and re-emergence of infectious diseases: bibliometric analysis and literature-supported studies on zoonoses.
    Walter Leal Filho, Gustavo J Nagy, Gouvidé Jean Gbaguidi, Shlomit Paz, Maria Alzira Pimenta Dinis, Johannes M Luetz, Ayyoob Sharifi.
      Climate change (CC) is increasingly recognised as a critical driver in the emergence and re-emergence of infectious diseases. The relationship between CC and infectious diseases is complex and multifaceted, encompassing changes in temperature, precipitation patterns, and extreme weather events. This study describes the role of CC in the emergence and re-emergence of infectious diseases, emphasising zoonoses. It used a mixed methodology, including an initial literature contextualisation and a bibliometric analysis, to identify key thematic research areas related to CC and zoonotic diseases and show their connections. The research relied on the Scopus database for the identification of relevant source literature and focused the search query on publications in English. VOSviewer was used to discover clear thematic clusters that illustrate what research areas have been addressed in the literature and how they are interlinked. In addition, the research selected and analysed twelve literature-supported studies to investigate the relevance of the zoonoses involved in infectious disease emergence and re-emergence linked to CC impacts. Many pathogens and their vectors, such as mosquitoes, ticks, and rodents, are sensitive to temperature and moisture. CC can expand or shift the geographical distribution of these vectors, bringing diseases to new areas. Warmer temperatures may allow mosquitoes that transmit diseases like malaria and dengue fever to survive and reproduce in regions that were previously too cold. Also, extreme events such as floods, droughts, and hurricanes can lead to immediate increases in waterborne and vector-borne diseases (VBD) by facilitating the spread of pathogens. There is a need to better understand the connections between CC and zoonoses. To address the challenges posed by zoonoses linked to CC, international organizations like the WHO should coordinate a global response to provide clear guidance. Governments must integrate CC and zoonoses into national health policies, ensuring that health frameworks address these interconnected risks. Funding should be allocated for research on the root causes of CC and for strengthening defenses, particularly in developing countries with fragile health systems. Additionally, enhanced communication, education, and training for healthcare professionals about the links between CC and zoonoses are essential for raising awareness and promoting proactive measures.
    Keywords:  Case studies; Climate Change (CC); Literature analysis; Strategies; Zoonoses
    DOI:  https://doi.org/10.1186/s42522-024-00127-3
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