bims-evares Biomed News
on Evaluation of research
Issue of 2025–02–16
72 papers selected by
Thomas Krichel, Open Library Society
  1. Bibliometric and visual analysis of suicide in aged people over the past 20 years.
  2. An Analysis of Social Media Engagement and Conventional Bibliometrics for Articles Related to Distal Radius Fractures.
  3. A bibliometric and visualized analysis of sleep problems in children with autism spectrum disorder.
  4. Mapping knowledge landscapes and emerging trends in artificial intelligence for antimicrobial resistance: bibliometric and visualization analysis.
  5. Mapping the landscape and research trend of imaging diagnosis in lymphoma: a bibliometric analysis from 1976 to 2024.
  6. The impact of bariatric surgery on gut microbiota: a bibliometric analysis of research trends and scientific contributions.
  7. Global research trends on fibromyalgia and exercise: a ten-year Web of Science-based bibliometric analysis.
  8. Trends in the immunotherapy for glioblastoma: A two-decade bibliometric analysis.
  9. The Development of Publications on Catheter-Related Bladder Discomfort: A Bibliometric Analysis.
  10. Research progress and perspectives on the application of tyramide signal amplification-based multiplex immunohistochemistry/immunofluorescence: a bibliometrics analysis.
  11. A bibliometric analysis of six decades of camel research in North Africa: Trends, collaboration, and emerging themes.
  12. New biomarkers for diagnosis of bladder cancer: a bibliometric analysis.
  13. Bibliometric analysis of ferroptosis: a comprehensive evaluation of its contribution to lung cancer.
  14. Research status and trends of functional magnetic resonance imaging technology in the field of acupuncture: a bibliometric analysis over the past two decades.
  15. Research hotspots and trends in the application of electroencephalography for assessment of disorders of consciousness: a bibliometric analysis.
  16. Advancements in rheumatoid arthritis immunotherapy: a comprehensive bibliometric analysis of research trends and hotspots (2003-2023).
  17. Bibliometric analysis of neutrophil extracellular traps induced by protozoan and helminth parasites (2008-2024).
  18. A bibliometric analysis of the top 100 most cited articles on corticospinal tract regeneration from 2004 to 2024.
  19. Global research trends and hotspots in the application of lasers for acne treatment from 1986 to 2022: bibliometric and visual analysis.
  20. Contribution from the SAARC Region to Ophthalmic Research: A Bibliometric Analysis.
  21. The impact of social media on sleep journals: analyzing the correlation between altmetrics and citation count.
  22. Global Trends in the Value of Author Order Across Medical Publications: A Cross-Sectional Bibliometric Study.
  23. Online marketing and brand awareness for HEI: A review and bibliometric analysis.
  24. A general analysis of the impact of international collaboration on the citation indices of scientific publications from 60 institutions across five continents.
  25. In vivo confocal microscopy in ophthalmology: research trends from a bibliometric analysis.
  26. A bibliometric analysis of immune response in oral cancer.
  27. Hotspots and Trends in Research on Mental Health of the Rural Elderly: A Bibliometric Analysis Using CiteSpace.
  28. Global research trends on gastrointestinal cancer and mental health (2004-2024): a bibliographic study.
  29. Current update on surgical management for spinal tuberculosis: a scientific mapping of worldwide publications.
  30. Trends in the Application of Citizen Science in Waterbird Conservation: A Bibliometric Analysis.
  31. Global Research Trends and Focus on the Link Between Heart Failure and NLRP3 Inflammasome: A Bibliometric Analysis From 2010 to 2024.
  32. Trends and emerging hotspots in RNAi-based arthropod pest control: A comprehensive bibliometric analysis.
  33. Postoperative Thirst in Surgical Patients: A Bibliometric Study.
  34. Research progress of TRPV4 in pain over the past 20 years: a bibliometric analysis.
  35. Mapping the Scientific Research on Nutrition and Mental Health: A Bibliometric Analysis.
  36. Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis.
  37. Research trends and hotspots in post-stroke speech rehabilitation: A bibliometric analysis.
  38. Carbon reduction and green finance innovations: A scientometric analysis using bibliometrics and DTM model.
  39. Panoramic quantitative and visualization-based bibliometric analysis of Mycoplasma pneumoniae.
  40. Assessing Gender Equality in Italian Animal Science: A Case Study on Academic Careers and Research Outcomes.
  41. A Bibliometric Analysis on Urticaria: Roles of Oxidative Stress, Inflammation, Immunity, and Treatment Modalities.
  42. Global research landscape and hotspots for ferroptosis in glioma: A comprehensive bibliometric and visual analysis.
  43. Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis.
  44. Research Trends and Hot Topics of Nanozymes in Wound Care: A Bibliometric Analysis.
  45. Quantity versus quality: analysis of research publications in the 2023 neurosurgery match.
  46. Bibliometric analysis of the impacts of COVID-19 on the mental health of college students.
  47. A Step-By-Step Guide of Bibliometric Study for Healthcare and Allied Research.
  48. A Bibliometric Analysis of Healthcare Intervention-Related Studies Reporting Patient and Public Involvement and Engagement.
  49. Scientometric analysis of research trends in hemorrhagic fever with renal syndrome: A historical review and network visualization.
  50. Recent Progress and Perspectives on Functional Materials and Technologies for Renewable Hydrogen Production.
  51. Knowledge mapping and trends in implant-supported removable partial dentures.
  52. Use of Digital Health Technologies for Dementia Care: Bibliometric Analysis and Report.
  53. Long COVID Research, 2020-2024: A PubMed-Based Bibliometric Analysis.
  54. Exploring Trends and Clusters in Human Posture Recognition Research: An Analysis Using CiteSpace.
  55. Global trends and challenges in childhood caries: a 20-year bibliometric review.
  56. A Bibliometric and Systematic Review of the Use of Recycled Composite Materials with an Emphasis on the Mechanical Performance of Structures.
  57. Research Domain Criteria in NIMH Grants Characterized Using Large Language Models.
  58. Research trends 2024-2025.
  59. Comprehensive review of mapping climate change impacts on tea cultivation: bibliometric and content analysis of trends, influences, adaptation strategies, and future directions.
  60. Human capital, gender, institutional environment and research funding: Determinants of research productivity in German psychology.
  61. Research trends in the use of nanobodies for cancer therapy.
  62. Global hotspots and trends of nutritional supplements for sick populations from 2000 to 2024.
  63. CO2 Capture: A Comprehensive Review and Bibliometric Analysis of Scalable Materials and Sustainable Solutions.
  64. [Gender differences in career paths in medical academia: a nationwide study in the Netherlands].
  65. Exploring the science and data foundation for Federal public lands decisions.
  66. [Beyond quantity: rethinking quality and integrity in scientific research.]
  67. The inaccurate citation of the "Universal Declaration of Animal Rights" (UDAR) in the scientific literature: a scoping review.
  68. A Cross-Sectional Public Data Study of Female Leaders in Surgical Critical Care Fellowships.
  69. Research status of traditional & complementary medicine systems across the world.
  70. Publication bias in the social sciences since 1959: Application of a regression discontinuity framework.
  71. Comments on "Research trends on the relationship between air pollution and cardiovascular diseases in 2013-2022 - A scientometric analysis".
  72. Cochrane Reviews' authorship has become more gender-diverse but remains geographically concentrated: A meta-research study.
  1. Front Psychiatry. 2025 ;16 1469853
    Bibliometric and visual analysis of suicide in aged people over the past 20 years.
    Shao-Kui Kan, Ying-Li Zhang, Xue-Xia Bai, Bo Peng.
       Background: The rapid aging of the global population presents pressing public health challenges, notably an increase in suicide rates among older adults. Despite this critical issue, there is a scarcity of comprehensive assessments regarding the existing literature on suicide within this demographic. This study seeks to employ bibliometric analysis and knowledge mapping to elucidate prevailing research trends and the overall status of this field.
    Methods: We performed a comprehensive computer-based search of the Web of Science Core Collection to identify relevant articles and reviews concerning suicide in the elderly. A bibliometric analysis was conducted, examining various aspects including countries or regions, institutions, authors, journals, keywords, and references. This analysis utilized tools such as CiteSpace, VOSViewer, Pajek, and Excel 365 to facilitate a thorough assessment.
    Results: The analysis covered 1,116 publications from 2005 to 2024. The annual number of publications showed a fluctuating upward trend, with notable decreases in 2007, 2012, 2015, 2017, and 2022, and increases in 2009, 2013, 2016, and 2019, peaking at 121 in 2021, with citations reaching 4,741 in 2022, but declining since then. The United States stands out as the most productive and influential country in the field, boasting the highest number of publications and citations. The country is home to institutions leading in both publication and citation metrics. Prominent authors contributing significantly to this domain include Conwell Yeates, Van Orden Kimberly A., and Waern Margda. Key journals disseminating crucial research are the Journal of Affective Disorders, American Journal of Geriatric Psychiatry, and Lancet. Frequent keywords in this field encompass depression, suicidal ideation, suicide, older-adults, risk, risk factors, prevalence, older adults, ideation, behavior, health, mental health, life, age, people, prevention, symptoms, scale, population, and elderly. The contemporary research emphasis is primarily on identifying, treating, and preventing the suicide risk associated with depression in older adults.
    Conclusions: This study highlights the growing research focus on suicide in older adults, particularly related to depression and the identification, treatment, and prevention of suicide risk. The findings underscore the need for targeted prevention strategies and further investigation in this critical public health area.
    Keywords:  Citespace; VOSviewer; aged; bibliometric; depression; suicide
    DOI:  https://doi.org/10.3389/fpsyt.2025.1469853
  2. J Hand Surg Am. 2025 Feb 08. pii: S0363-5023(25)00005-X. [Epub ahead of print]
    An Analysis of Social Media Engagement and Conventional Bibliometrics for Articles Related to Distal Radius Fractures.
    David Cornwell, Yagiz Ozdag, Fenil R Bhatt, Victoria C Garcia, Joel C Klena, Louis C Grandizio.
       PURPOSE: As methods of research publication and promotion evolve, conventional bibliometric analyses may not provide a complete representation of audience engagement with peer-reviewed literature. Our purpose was to assess for correlations between social media engagement (Altmetric attention score [AAS]) and conventional article metrics (citation density [CD] and journal impact factor).
    METHODS: Distal radius fracture (DRF) articles with the highest number of citations were identified using Web of Science and imported into Altmetric. The Altmetric database quantifies an article's online engagement and social media footprint to determine the AAS. We evaluated four metrics pertaining to the top 100 DRF articles: AAS, social media mentions (SMM), journal impact factor, and CD. Spearman's ρ was calculated between four pairings of these metrics. Confidence intervals corresponding to each Spearman's ρ were obtained via bootstrapping over 10,000 replications.
    RESULTS: Of the 1,000 most frequently cited DRF articles, 333 (33%) generated an AAS. The AAS of the top 100 articles according to AAS ranged from 6 to 317 with a mean of 16. Articles were predominantly original research (71%), followed by reviews (21%). A moderately positive correlation (ρ = 0.55) between AAS and SMM was found. Citation density versus SMM and CD versus AAS were both found to be weakly positively correlated with a ρ of 0.34 and 0.30, respectively.
    CONCLUSIONS: For the 1,000 most frequently cited articles related to DRFs, 33% generated an AAS. Citation density demonstrated weak, positive correlations with both SMM and AAS. In addition, we found a moderately positive correlation between AAS and SMM.
    CLINICAL RELEVANCE: These data suggest that online and social media engagement is weakly correlated with increased citations for peer-reviewed articles related to DRFs. Although AAS cannot determine article quality or scientific merit, online dissemination of peer-reviewed research may be an effective means of promoting academic publications and increasing citations.
    Keywords:  Citation density; distal radius fractures; hand surgery; impact factor; social media
    DOI:  https://doi.org/10.1016/j.jhsa.2025.01.005
  3. Res Dev Disabil. 2025 Feb 10. pii: S0891-4222(25)00027-7. [Epub ahead of print]158 104943
    A bibliometric and visualized analysis of sleep problems in children with autism spectrum disorder.
    Fethiye Kılıçaslan, Hülya Karataş, Ümit Doğan.
       PURPOSE: Children diagnosed with autism spectrum disorder (ASD) exhibit a significantly higher prevalence of sleep problems compared to their typically developing peers. Despite numerous studies on ASD and sleep, a comprehensive bibliometric analysis on this topic is lacking. This study aims to analyze publications on sleep problems in children with ASD using bibliometric methods.
    METHODS: Research articles on sleep problems in children with ASD were obtained from the Web of Science Core Collection (WOSCC) database. Between 1984 and 2024, 462 studies by 1896 authors were published in 164 journals. We used bibliometrics to analyze papers on sleep problems in children with ASD, to draw the network of authors, countries, journals, and keywords in this field, and to visualize the results.
    RESULTS: The number of publications examining sleep problems in children with ASD has increased since 2011. The highest number of published studies is in 2021. The leading country in research is the USA, and the most productive author in this field is Malow B. In recent years, burst keywords were intervention, circadian rhythm, screen time, and melatonin.
    CONCLUSION: Increased attention has been paid to sleep in children with ASD. It is believed that this bibliometric analysis can help determine the gap in the field of sleep in children with ASD and help new studies to be conducted.
    Keywords:  ASD; Bibliometric; Children; Sleep; Visualization; Web of science
    DOI:  https://doi.org/10.1016/j.ridd.2025.104943
  4. Front Med (Lausanne). 2025 ;12 1492709
    Mapping knowledge landscapes and emerging trends in artificial intelligence for antimicrobial resistance: bibliometric and visualization analysis.
    Zhongli Wang, Gaopei Zhu, Shixue Li.
       Objective: To systematically map the knowledge landscape and development trends in artificial intelligence (AI) applications for antimicrobial resistance (AMR) research through bibliometric analysis, providing evidence-based insights to guide future research directions and inform strategic decision-making in this dynamic field.
    Methods: A comprehensive bibliometric analysis was performed using the Web of Science Core Collection database for publications from 2014 to 2024. The analysis integrated multiple bibliometric approaches: VOSviewer for visualization of collaboration networks and research clusters, CiteSpace for temporal evolution analysis, and quantitative analysis of publication metrics. Key bibliometric indicators including co-authorship patterns, keyword co-occurrence, and citation impact were analyzed to delineate research evolution and collaboration patterns in this domain.
    Results: A collection of 2,408 publications was analyzed, demonstrating significant annual growth with publications increasing from 4 in 2014 to 549 in 2023 (22.7% of total output). The United States (707), China (581), and India (233) were the leading contributors in international collaborations. The Chinese Academy of Sciences (53), Harvard Medical School (43), and University of California San Diego (26) were identified as top contributing institutions. Citation analysis highlighted two major breakthroughs: AlphaFold's protein structure prediction (6,811 citations) and deep learning approaches to antibiotic discovery (4,784 citations). Keyword analysis identified six enduring research clusters from 2014 to 2024: sepsis, artificial neural networks, antimicrobial resistance, antimicrobial peptides, drug repurposing, and molecular docking, demonstrating the sustained integration of AI in antimicrobial therapy development. Recent trends show increasing application of AI technologies in traditional approaches, particularly in MALDI-TOF MS for pathogen identification and graph neural networks for large-scale molecular screening.
    Conclusion: This bibliometric analysis shows the importance of artificial intelligence in enhancing the progress in the discovery of antimicrobial drugs especially toward the fight against AMR. From enhancing the fast, efficient and predictive performance of drug discovery methods, current AI capabilities have revealed observable potential to be proactive in combating the ever-growing challenge of AMR worldwide. This study serves not only an identification of current trends, but also, and especially, offers a strategic approach to further investigations.
    Keywords:  antibiotics; antimicrobial resistance; artificial intelligence; bibliometric analysis; deep learning
    DOI:  https://doi.org/10.3389/fmed.2025.1492709
  5. Front Med (Lausanne). 2025 ;12 1516817
    Mapping the landscape and research trend of imaging diagnosis in lymphoma: a bibliometric analysis from 1976 to 2024.
    Yi Ma.
       Background: Over the past five decades, extensive research has been conducted on lymphoma imaging diagnostics; however, no bibliometric analysis has been performed in this area. Therefore, we undertook a bibliometric analysis to clarify the progress and current state of research in this field.
    Methods: We conducted a search of the Web of Science Core Collection database for articles related to imaging diagnosis and lymphoma, focusing exclusively on English-language publications up to June 20, 2024. We analyzed and visualized various aspects, including publication trends, journals, co-authorship networks, countries, institutions, and keywords. To examine research trends in this field, we utilized bibliometric analysis tools such as VOSviewer, CiteSpace, and R4.3.3.
    Results: From 1976 to 2024, a total of 10,410 publications were produced on this topic, with 2021 marking the peak in publication numbers. The most significant contributions in this research area were found in the fields of Radiology, Nuclear Medicine & Medical Imaging, Oncology, and Hematology. The United States, China, and Japan were the leading contributors. Zucca Emanuele ranked first among authors, followed closely by Meignan Michel. In terms of institutions, Assistance Publique Hôpitaux de Paris was the most prominent. The most frequently used keywords included positron emission tomography, computed tomography, and non-Hodgkin's lymphoma.
    Conclusion: This study presented a bibliometric analysis of lymphoma imaging diagnosis, highlight showcasing research trends, influential significant studies, and collaborative networks. The analysis identified key contributions to the field and provide insights for future research directions.
    Keywords:  CT; MR; bibliometric analysis; imaging diagnosis; lymphoma
    DOI:  https://doi.org/10.3389/fmed.2025.1516817
  6. Front Microbiol. 2025 ;16 1523809
    The impact of bariatric surgery on gut microbiota: a bibliometric analysis of research trends and scientific contributions.
    Shuaichang Gong, Xiabiao Zhang, Xiaoliang Chen, Ping Wan, Longfei Zhou, Jun Zhang.
       Background: Obesity is a prevalent global disease closely linked to various chronic conditions. Bariatric surgery (BS) is currently recognized as the most effective treatment. Increasing evidence suggests that BS alters the gut microbiota (GM), which plays a crucial role in postoperative weight loss. However, there has been no systematic bibliometric analysis exploring the relationship between BS and GM to date.
    Methods: We conducted a literature search on BS and GM from January 1, 1981, to May 25, 2024, within the Web of Science Core Collection (WoSCC). We utilized Excel 2021, VOSviewer 1.6.19, CiteSpace 6.2.R3, and the R package "bibliometrix" 4.3.0, along with the online bibliometric analysis platform (https://bibliometric.com/app), to visualize publishing trends and research hotspots in this field.
    Results: A total of 2,542 articles meeting the criteria were included. Since 2015, the rate of publication has significantly accelerated. The United States leads in both the number of publications and average citations per article. The University of São Paulo is the most active institution, whereas the University of Copenhagen has the highest average citation count. Obesity Surgery is the journal with the highest number of publications, and the most prolific author is Karine Clement. Keyword and thematic analyses indicate that "gut microbiota" and "bariatric surgery" are the primary research hotspots for future studies.
    Conclusion: In summary, this field is garnering increasing attention. Our findings suggest that future research will likely focus on the effects of bariatric surgery on gut microbiota and its biological mechanisms, the role of gut microbiota in the weight loss process, and the development of combined treatments based on gut microbiota.
    Keywords:  bariatric surgery; bibliometric analysis; gut microbiota; metabolic syndrome; obesity
    DOI:  https://doi.org/10.3389/fmicb.2025.1523809
  7. Rheumatol Int. 2025 Feb 13. 45(3): 50
    Global research trends on fibromyalgia and exercise: a ten-year Web of Science-based bibliometric analysis.
    Hilmi Erdem Sumbul, Ramazan Azim Okyay, Dana Bekaryssova, Burhan Fatih Kocyigit.
      Fibromyalgia causes widespread pain, exhaustion, and cognitive deficits, lowering sufferers' quality of life. Exercise supports the management of fibromyalgia by reducing pain and improving mood. This study examines global fibromyalgia and exercise research trends using bibliometric analysis to identify major contributors, citation patterns, and prospective research areas. Data were obtained from the Web of Science (WoS) database utilizing the keywords "fibromyalgia exercise" for publications from 2014 to 2023. The inclusion criteria prioritized original articles and reviews published in the English language. Bibliometric characteristics were examined, including publication year, country, journal, and citation metrics. Statistics adjusted for population and gross domestic product (GDP) were computed to evaluate research productivity in relation to economic and demographic variables. A total of 497 publications satisfied the inclusion criteria. A significant increase trend in publication counts was noted (p = 0.003), with Spain (25.75%), the United States (15.09%), Brazil (13.88%), Türkiye (7.24%), and Sweden (5.23%) identified as the major contributors. Publications were produced by 37 countries, 19 of which were the main active countries. Spain displayed remarkable productivity, ranking first in population- and GDP-adjusted contributions. Based on publication type, 388 (78.06%) were original articles, and the rest were reviews. The median number of original article and review citations were 11 (min = 0; max = 289) and 14 (min = 0; max = 1092). Review citations outnumbered original articles (p = 0.013). The median number of citations for SCIE and/or SSCI and ESCI articles were 12 (min = 0; max = 1092) and 3 (min = 0; max = 92). SCIE and/or SSCI articles were significantly more cited than ESCI ones (p < 0.001). INT J ENV RES PUB HE (n = 18), RHEUMATOL INT (n = 17), ARCH PHYS MED REHAB (n = 15), J CLIN MED (n = 14) and DISABIL REHABIL (n = 13) were the top five journals in terms of article count. This bibliometric analysis evaluates and summarizes global scholarly output on fibromyalgia and exercise, underscoring the increasing research interest in the two. High-income countries, notably Spain, the United States, and Sweden, significantly contributed to the area, underscoring differences in research capacities.
    Keywords:  Bibliometric analysis; Bibliometrics; Exercise; Fibromyalgia; Rehabilitation
    DOI:  https://doi.org/10.1007/s00296-025-05807-5
  8. Hum Vaccin Immunother. 2025 Dec;21(1): 2466299
    Trends in the immunotherapy for glioblastoma: A two-decade bibliometric analysis.
    Zhi Long, Zhenjie Yi, Wei Yan, Hongxin Wang.
      Glioblastoma is a life-threatening primary malignant brain tumor with an unfavorable prognosis. Contributing factors to its poor outcome include tumor heterogeneity, low mutational burden, and immunosuppression within the tumor microenvironment. Recognizing these challenges, immunotherapeutic strategies have emerged as a promising avenue for glioblastoma treatment. Although several dynamic research and scientific trend have increasingly taken pace in the immunotherapeutic approaches to glioblastoma, systematic bibliometric studies on such trends are few. On this note, this study explores a bibliometric analysis of the research hotspots and trends in glioblastoma immunotherapy. We conducted a search in the Web of Science Core Collection database for articles on glioblastoma immunotherapy published between 2004 and 2024. Using VOSviewer and CiteSpace software, we analyzed collected articles to explore aspects such as country of origin, journal of publication, affiliated institute, authorship, keywords, and citation patterns. As of May 1, 2024, we retrieved 3,729 papers on Glioblastoma Immunotherapy. In the field of glioblastoma immunotherapy, the United States stands out as the leading contributor, with 1,708 publications and a substantial 90,590 citations. Following closely, China has made significant contributions through 926 publications, earning 17,533 citations, while Germany adds to the body of knowledge with 349 publications and 16,355 citations. Furthermore, Authoritative journals in this field include Clinical Cancer Research and Neuro-Oncology. The top five keywords during this period were temozolomide, radiotherapy, dendritic cell, cytotoxic T lymphocyte, and vaccination. Moreover, Hotspots in the field include immune checkpoint inhibitors and chimeric antigen receptor T cell therapy.
    Keywords:  Bibliometric analysis; CiteSpace; VOSviewer; glioblastoma; immunotherapy
    DOI:  https://doi.org/10.1080/21645515.2025.2466299
  9. Ther Clin Risk Manag. 2025 ;21 137-147
    The Development of Publications on Catheter-Related Bladder Discomfort: A Bibliometric Analysis.
    Wencai Jiang, Xuemeng Chen, Yanhua Peng, Wenhu Zhai, Xianjie Zhang, Yukai Zhou, Rui Zhou.
       Background: Catheter-related bladder discomfort (CRBD) is a risk factor that impacts postoperative recovery and still troubles patients and healthcare staff. The present study is a bibliometric analysis of CRBD.
    Methods: The publications on CRBD were retrieved from the Web of Science Core Collection. VOSviewer and Excel were applied to present the current status and hot spots of CRBD research. We analyzed parameters such as the annual number of publications, countries/regions, organizations, authors, journals, and keywords of the articles in this area by generating visualization graphs.
    Results: A total of 127 articles were eligible, recorded by 78 journals, and drafted by 672 authors from 169 organizations in 26 countries/regions. The main type of these articles is randomized trial. Park Hee-Pyoung, Kim Hyun-Chang, and Cui Yuanshan are the most productive authors with 5 articles. Sichuan University, Seoul National University, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Capital Medical University, and Qingdao University published more articles on CRBD worldwide. China ranks No. 1 in terms of the number of publications, followed by South Korea and India. Journals specialized in anesthesiology, such as BMC Anesthesiology, Journal of Anesthesia, and British Journal of Anesthesia, are more popular with researchers in this area. The research hot spots of CRBD have concentrated on the prevention and treatment of CRBD.
    Conclusion: Though formal research on CRBD started late, there is a rising tendency for the number of publications. Authors and academic teams from Asia have made significant contribution to CRBD. Journals specialized in anesthesiology are priorities for publishing articles. Previous studies mainly focused on the pharmacological and pharmacological methods to CRBD. However, CRBD is not fully settled. Either clinical or experimental studies are still needed to further improve CRBD.
    Keywords:  CRBD; bibliometric analysis; catheter-related bladder discomfort; hot spots
    DOI:  https://doi.org/10.2147/TCRM.S493703
  10. Front Oncol. 2024 ;14 1473414
    Research progress and perspectives on the application of tyramide signal amplification-based multiplex immunohistochemistry/immunofluorescence: a bibliometrics analysis.
    Xiaotong Yu, Chen Huang, Yan Song, Chun Zhang, Debo You, XuRan Dong, DeFu Wu, Alan Keith Meeker, Hao Feng, Yuqing Wang.
       Background and aims: Multiplex immunohistochemistry/immunofluorescence (mIHC/IF), which uses the tyramide signal amplification (TSA) technique, enables sequential staining of multiple targets in formalin-fixed paraffin-embedded (FFPE) samples without worrying about cross-reactivity. This approach has received considerable attention from researchers over the past decades. This article aims to provide a bibliometric analysis of the research progress and perspectives on the application of TSA-based mIHC/IF.
    Methods: We collected all the TSA-based mIHC/IF documents published between 2007 and 2023 from the Web of Science Core Collection (WoSCC) database. CiteSpace, VOSviewer and Bibliometrix R Package were used to perform the bibliometrics analysis, including details about annual publications, countries, institutions, authors, journals, and research topics and hotspots.
    Results: A total of 873 relevant publications (811 articles and 62 reviews) with a time span of 17 years (2007-2023) were obtained. The number of annual publications started to increase rapidly since 2016. The United States (307, 35.17%) and the People's Republic of China (297, 34.02%) are the top two listed countries for both the number of articles produced and the citations. The University of Texas System (53, 6.07%) was the most productive institution. Integrating these results of hotspot and frontier analysis, TSA-based mIHC/IF provides significant benefits, particularly in neurology, cancer and immunology.
    Conclusion: This study conducted a comprehensive bibliometric analysis for the use of TSA-based mIHC/IF. As TSA-based mIHC/IF and its associated imaging systems and analytic software progress, it will become the most promising tool for describing the variety of the whole tissue for a better understanding of pathological or physiological behavior.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; multiplex immunohistochemistry/immunofluorescence; tyramide signal amplification
    DOI:  https://doi.org/10.3389/fonc.2024.1473414
  11. Open Vet J. 2024 Dec;14(12): 3505-3524
    A bibliometric analysis of six decades of camel research in North Africa: Trends, collaboration, and emerging themes.
    Razan Naji, Mahmoud Kandeel, Maryam Mahmoud.
       Background: Camels play a crucial role in North Africa's economy and agriculture, providing essential products, transportation, and tourism.
    Aim: This study conducts a comprehensive bibliometric analysis of camel research in North Africa between 1964 and 2024. The primary objectives are to evaluate research productivity, identify key contributors, and highlight emerging trends.
    Methods: Data were collected from the Scopus database, which contained 1805 research documents. Bibliometrix and VOSviewer were used to visualize co-authorship networks, citation patterns, and keyword trends.
    Results: The research output has increased dramatically since the mid-2000s, with a peak in publications between 2018 and 2020. Collaborations made up 53.91% of articles. The research clusters in camel studies from North Africa include camel physiology and reproduction, focusing on topics such as ovarian function, semen preservation, and seasonal variations; Microbiology and genetics, addressing microbial infections and genetic diversity; Epidemiology and disease control, which covers studies on disease prevalence, risk factors, and seroprevalence; and Camel milk research, emphasizing its nutritional and therapeutic properties, particularly related to oxidative stress and antioxidants.
    Conclusion: Camel research in North Africa has grown significantly, with a focus on health, genetics, and sustainability. However, there are still gaps in molecular and transdisciplinary research, notably in areas such as genetic diversity and ecological integration. Future research should prioritize these areas and foster greater international collaboration to address pressing concerns like climate change.
    Keywords:  Bibliometrix; Camel health; Camel research; Genetics; North Africa
    DOI:  https://doi.org/10.5455/OVJ.2024.v14.i12.34
  12. Arch Ital Urol Androl. 2025 Feb 11. 13396
    New biomarkers for diagnosis of bladder cancer: a bibliometric analysis.
    Roberto Falabella, Valentina De Simone, Felice Crocetto, Francesco Del Giudice, Angelo Porreca, Nazario Foschi, Biagio Barone, Luca Di Gianfrancesco, Valentina Di Pasquale, Vincenzo Francesco Caputo.
       BACKGROUND/OBJECTIVES: Bladder cancer is a multifactorial disease, ranking as the 10th most common cancer globally and the fourth most common cancer in men and the ninth in women in the Western world. This bibliometric analysis aims to identify and evaluate scientific literature addressing new biomarkers for bladder cancer diagnosis, as well as to identify the most prolific organizations, authors, journals, countries, and keywords within this research domain.
    METHODS: An electronic search was conducted using Elsevier's Scopus database. From a total of 940 retrieved papers (published between 2019 and 2024), 493 were selected. For data analysis and visualization, the titles of articles, year of publication, countries, authors, journals, articles, and keywords were analyzed using Microsoft Excel, VOSviewer, and Biblioshiny.
    RESULTS: China published the most papers (200 articles) and received the highest number of citations, followed by the USA. While some countries, such as Egypt and India, published exclusively Single Country Publications (SCPs), others demonstrated a higher level of international collaboration, with at least half of their publications being Multi-Country Publications (MCPs). Countries with higher rates of MCPs were Greece (66.6%), Italy (53.8%), Korea, and France (50%). The journals that produced the most publications and received the highest number of citations were Cancers, International Journal of Molecular Sciences, and Frontiers in Oncology, confirming their role in producing high-impact research.
    CONCLUSIONS: The consistent distribution of publications over the years considered indicates a sustained interest in this field.
    DOI:  https://doi.org/10.4081/aiua.2025.13396
  13. Front Genet. 2024 ;15 1449491
    Bibliometric analysis of ferroptosis: a comprehensive evaluation of its contribution to lung cancer.
    Feifei Yao, Feng Guo, Chuanzhong Sun, Erdong Wang, Hang Wang, Na Li.
       Objectives: This study employs bibliometric analysis to track evolution and identify trends of key topics in ferroptosis within the context of lung cancer. By identifying emerging research areas, our aim is to provide valuable insights and directions for researchers in this field.
    Methods: Relevant papers and reviews on ferroptosis in lung cancer were retrieved from the Web of Science Core Collection database on 5 February 2024. Bibliometric analysis was conducted using CiteSpace 6.2.R3, VOSviewer 1.6.20, R 4.3.0, Bibliometric and Microsoft Excel 2019.
    Results: From 2015 to 2020, publications related to ferroptosis in lung cancer were sparse but showed a steady increase. Post-2020, there has been a significant surge, with a 6.4-fold increase observed by 2023. Overall, authors from 4,033 institutions across 42 countries/regions contributed 606 papers published in 262 academic journals. China emerged as the leading contributor, while the United States maintained dominance. Lifang Ma was the most prolific author, with DIXON SJ, YANG WS, and STOCKWELL BR being the most frequently co-cited. Effective communication and collaboration among scholars are lacking. Key journals include Frontiers in Pharmacology for publication output, and Nature and Cell for citation frequency. Research focuses on molecular mechanisms of ferroptosis, including endoplasmic reticulum stress, tumor microenvironment, and autophagy. Therapeutic targets like GPX4, SLC7A11, P53, FSP1, Nrf2, LSH, STYK1/NOK, and ACSL4 are prominent. Traditional Chinese medicine also shows clinical value in ferroptosis research.
    Conclusion: Ferroptosis, as a promising research avenue with significant clinical applications in lung cancer, continues to undergo rapid development. The study of iron death in lung cancer will remain a critical research focus in the future.
    Keywords:  CiteSpace; bibliometric analysis; ferroptosis; knowledge mapping; lung cancer
    DOI:  https://doi.org/10.3389/fgene.2024.1449491
  14. Front Neurosci. 2025 ;19 1489049
    Research status and trends of functional magnetic resonance imaging technology in the field of acupuncture: a bibliometric analysis over the past two decades.
    Zhongke Wang, Lu Chen, Tianyu Jiang, Qi Zhang, Jinying Zhao, Fuchun Wang.
       Objective: Although fMRI has been widely used in the field of acupuncture. However, the literature analysis in this field still has significant differences. This study summarizes the current status of functional magnetic resonance imaging (fMRI) in the field of acupuncture and moxibustion and predicts its future trends through Web of Science bibliometric analysis.
    Methods: This study uses "fMRI" and "acupuncture" as keywords to search for literature related to functional magnetic resonance imaging (fMRI) in acupuncture research in the Web of Science Core Collection database from January 1, 2004, to April 30, 2024. Visualization analyses were conducted using Citespace (version 6.3 R1) and VOSviewer (version 1.6.20). Citespace was employed to analyze annual publications, countries, institutions, keywords, and co-cited references. VOSviewer was used to analyze authors and co-cited authors, as well as journals and co-cited journals.
    Results: From 2004 to 2024, a total of 967 publications were retrieved, of which 557 were included after screening. Despite annual fluctuations, the overall trend shows an increase. China and the Chinese Academy of Sciences are the countries and institutions with the highest number of publications, with Tian, J being the author with the most publications, and Kong, J having the highest Co-citation frequency. The article by Dhond, RP, published in 2008, has the highest Co-citation frequency among the co-cited literature. Evidence-based Complementary and Alternative Medicine is the journal with the most publications, while Neuroimage is the co-cited journal with the highest citation frequency. Keyword co-occurrence and burst reveal the main research hotspots, including the diversity of intervention methods, cortical activation, mechanisms related to pain-associated diseases, and brain-related diseases. Keyword burst detection reflects emerging trends, including meta-analysis and systematic reviews, the relationship between ischemic stroke and women, and the connection between mild cognitive impairment and prevention.
    Conclusion: This study employs bibliometric methods to explore the current status, research hotspots, and frontier issues regarding the application of functional magnetic resonance imaging (fMRI) technology in the field of acupuncture, providing new perspectives and directions for acupuncture fMRI research.
    Keywords:  Citespace; VOSviewer; acupuncture; bibliometric analysis; fMRI
    DOI:  https://doi.org/10.3389/fnins.2025.1489049
  15. Front Neurol. 2024 ;15 1501947
    Research hotspots and trends in the application of electroencephalography for assessment of disorders of consciousness: a bibliometric analysis.
    Jiawen Chen, Yanhua Shi, Zhao Dong, Feng Xu, Mengyu Zhou, Jing Zhu, Jie Gao, Su Liu.
       Objective: Disorders of consciousness (DoC) result from severe traumatic brain injury and hypoxia or ischemia of brain tissues, leading to impaired perceptual abilities. Electroencephalography (EEG) is a non-invasive and widely applicable technology used for assessing DoC. We aimed to identify the research hotspots in this field through a systematic analysis.
    Methods: Relevant studies published from January 1, 2004 to December 31, 2023 were retrieved from the Web of Science Core Collection database. The data were analyzed and visualized using CiteSpace, VOSviewer, and SCImago Graphica.
    Results: In total, 1,639 relevant publications were retrieved. The country with the highest number of publications was the United States, the most productive institution was Harvard University, the journal with the highest output was Clinical Neurophysiology, and the journal with the highest total number of citations was Neurology. The author with the most publications was Steven Laureys and the most common keyword was "vegetative state."
    Conclusion: The field is undergoing rapid development, characterized by a proliferation of advanced technologies and an increased emphasis on international collaboration. The document offers an impartial perspective on the advancements of the research study for the benefit of the researchers.
    Keywords:  bibliometric analysis; disorders of consciousness; electroencephalography; minimally conscious state; research trends; unresponsive wakefulness syndrome
    DOI:  https://doi.org/10.3389/fneur.2024.1501947
  16. Clin Exp Rheumatol. 2025 02 11.
    Advancements in rheumatoid arthritis immunotherapy: a comprehensive bibliometric analysis of research trends and hotspots (2003-2023).
    Yi Tian, Miao Jin, Huiying Li, Dandi Li, Yinhui Pei.
       OBJECTIVES: To analyse research trends and developments in rheumatoid arthritis (RA) immunotherapy through a comprehensive bibliometric analysis of literature from 2003 to 2023.
    METHODS: Publications related to RA immunotherapy were retrieved from Web of Science Core Collection database using specified search terms. Bibliometric analysis was performed with VOSviewer, CiteSpace, Pajek, and R packages to examine publication patterns, international collaborations, research hotspots, and emerging trends. Analysis covered publication outputs, country contributions, institutional networks, and keyword evolution patterns.
    RESULTS: Analysis based on a total of 940 publications showcased that the associated researches featured exponential growth (R²=0.885) over the study period. The United States led with 285 publications (30.3%), followed by China (187, 19.9%) and Germany (156, 16.6%). International collaboration intensity increased, with average collaborating countries per paper rising from 1.8 to 2.7. Research focus evolved through three phases: fundamental immunology (2003-2010), therapeutic development (2011-2017), and precision medicine (2018-2023). Current hotspots encompassed immunomodulation mechanisms (38% of keywords), immune-related adverse events management, as well as cancer immunity interactions. Emerging trends highlighted nanotechnology applications and microbiome research, with respective growth rates of 218% and 245% in recent years.
    CONCLUSIONS: This analysis revealed significant evolution in RA immunotherapy research, characterised by increasing international collaboration and methodological sophistication. The involved fields displayed a clear transition from basic immunological research to precision medicine approaches. Emerging hotspots in nanotechnology and microbiome studies suggested promising therapeutic innovations. These findings were seen to provide valuable guidance for future research fields and resource allocation in RA immunotherapy.
    DOI:  https://doi.org/10.55563/clinexprheumatol/xo2fjd
  17. Front Immunol. 2025 ;16 1498453
    Bibliometric analysis of neutrophil extracellular traps induced by protozoan and helminth parasites (2008-2024).
    Tamara Muñoz-Caro, Elvira M Saraiva, Rafael M Mariante.
       Introduction: Parasitic diseases pose a significant global public health challenge, affecting billions of people and causing substantial economic losses in livestock and poultry. In the fight against these infections, neutrophils play a crucial role, employing various strategies, including the release of neutrophil extracellular traps (NETs). Recent studies have made significant progress in understanding NETs triggered by protozoa and helminths. However, a comprehensive bibliometric analysis that compiles these findings and identifies research hotspots and trends in this field is still lacking.
    Methods: We utilized the Web of Science Core Collection and Scopus databases to retrieve original articles on NETs induced by protozoa and helminths. After screening, the data was transferred to the visualization tools VOSviewer, Biblioshiny, and CiteSpace for analysis.
    Results: Our study included 159 original articles published in 69 journals, involving 909 authors from 270 institutions across 41 countries. Germany and Brazil have made the most significant contributions to the research on NETs and parasites, accounting for 45 and 32 publications, and 1,495 and 1,342 citations, respectively. Carlos Hermosilla and Anja Taubert (Justus Liebig University Giessen, Germany), and Elvira Saraiva (Federal University of Rio de Janeiro, Brazil), are leaders in the field, both in terms of publication output and citations. Frontiers in Immunology has consistently and significantly impacted the field, and an article in the Proceedings of the National Academy of Sciences of the United States of America providing the first direct evidence of NETs release in response to a parasite is by far the most cited. Current research focuses on malaria, Toxoplasma gondii, Besnoitia besnoiti, nematodes, and the mechanisms of NETs production and their effects on parasites and host cells. Emerging trends include therapeutic targeting of NETs and comparative studies across different host and parasite species.
    Conclusion: This study offers a comprehensive overview and visual analysis of NETs and parasites, highlighting key areas for future research.
    Keywords:  Biblioshiny; CiteSpace; NETs; VOSviewer; bibliometrics; heminths; neutrophils; protozoa
    DOI:  https://doi.org/10.3389/fimmu.2025.1498453
  18. Front Neurosci. 2024 ;18 1509850
    A bibliometric analysis of the top 100 most cited articles on corticospinal tract regeneration from 2004 to 2024.
    Saijilafu, Ling-Chen Ye, Huanyi Li, Haokun Li, Xinyi Lin, Kehui Hu, Zekai Huang, Chimedragchaa Chimedtseren, Linjun Fang, Saijilahu, Ren-Jie Xu.
       Objective: Here, bibliometric and visual analytical techniques were employed to assess the key features of the 100 most cited publications concerning corticospinal tract (CST) regeneration.
    Methods: Research was conducted within the Web of Science Core Collection to pinpoint the 100 most cited publications on CST regeneration. From these, comprehensive data encompassing titles, authorship, key terms, publication venues, release timelines, geographic origins, and institutional affiliations were extracted, followed by an in-depth bibliometric examination.
    Results: The 100 most cited publications were all published between 2004 and 2024. These seminal papers amassed an aggregate of 18,321 citations, with individual citation counts ranging from 83 to 871 and a median of 136 citations per paper. Schwab M. E., stood out as the most prominent contributor, with significant authorship in 9 of the 100 papers. The United States dominated the geographical distribution, accounting for 49 of the articles. With 17 publications, the University of California System led the institutional rankings. A thorough keyword analysis revealed pivotal themes in the field, encompassing the optic nerve, gene expression, CST integrity and regeneration, diffusion tensor imaging, myelin-associated glycoproteins, inhibitors of neurite outgrowth, and methods of electrical and intracortical microstimulation.
    Conclusion: This investigation provides a bibliometric analysis of CST regeneration, underscoring the significant contribution of the United States to this field. Our findings unveiled the dynamics and trends within the field of CST regeneration, providing a scientific foundation for advancing clinical applications. Building on this analysis, the clinical application of CST regeneration should be optimized through interdisciplinary collaboration, enabling the exploration and validation of a variety of therapeutic approaches, including the use of neurotrophic factors, stem cell therapies, biomaterials, and electrical stimulation. Concurrently, additional clinical trials are necessary to test the safety and efficacy of these therapeutic methods and develop assessment tools for monitoring the recovery of patients. Furthermore, rehabilitation strategies should be refined, and professional education and training should be provided to enhance the understanding of CST regeneration treatments among both medical professionals and patients. The implementation of these strategies promises to enhance therapeutic outcomes and the quality of life of patients with spinal cord injury (SCI).
    Keywords:  CiteSpace; VOSviewer; Web of Science Core Collection; bibliometric analysis; corticospinal tract regeneration
    DOI:  https://doi.org/10.3389/fnins.2024.1509850
  19. Lasers Med Sci. 2025 Feb 14. 40(1): 88
    Global research trends and hotspots in the application of lasers for acne treatment from 1986 to 2022: bibliometric and visual analysis.
    Sa'ed H Zyoud, Sari Taha, Samer Zyoud, Moyad Shahwan, Ammar A Jairoun, Samah W Al-Jabi.
      Conventional acne treatments are associated with side effects from medication and antibiotic resistance, leading to the search for alternative therapeutic modes of action, such as lasers. The considered bibliometric and visual analysis was designed to present the research publications related to the application of lasers in the treatment of acne from 1986 to 2022, identifying the trends and foremost contributing countries, institutions, and journals. The Scopus database was used to explore publications related to the use of lasers for the treatment of acne. The publications were reviewed based on predefined criteria, including the year of publication, study type, country of origin, affiliated institutions, journals, and citation patterns, employing descriptive analysis. The data were subsequently entered into Microsoft Excel 2016. Furthermore, for the creation of visualization maps depicting international collaborations and research hotspots, we employed VOSviewer software version 1.6.20. A total of 469 documents were retrieved from the Scopus database for analysis. Of those, 74.41% were original articles, 12.15% were reviews, 3.84% were letters, and 9.59% were other forms of publications. Since 2003, the number of publications has shown a consistent positive trend, with a slight plateau between 2012 and 2019. The United States was the most contributing country (33.26%), followed by South Korea (10.23%) and China (10.02%). The emerging research hotspots were "fractional laser therapy and carbon dioxide (CO2) lasers", "types of laser therapy and combination therapies for acne treatment", and "the effectiveness of laser treatments". This study is the first bibliometric analysis of the use of lasers in acne management. These findings indicate an increasing interest in this emerging field, especially in exploring the efficacy of various types and combinations of lasers. This study can help researchers and policymakers understand research trends and gaps to guide future research, collaboration, and decision-making.
    Keywords:  Acne; Global research; Laser; Scopus; VOSviewer
    DOI:  https://doi.org/10.1007/s10103-025-04353-7
  20. Pak J Med Sci. 2025 Feb;41(2): 614-621
    Contribution from the SAARC Region to Ophthalmic Research: A Bibliometric Analysis.
    Yousaf Jamal Mahsood, Rima Khan, Hira Wakil, Saima Farooq, Rashid Zia.
       Objective: To review the contributions to the ophthalmic research from the SAARC region in the top twenty ophthalmology journals.
    Methods: This was a bibliometric study and the top 20 ophthalmology journals, as ranked by the Scimago Journal Rankings (SJR) from 2021 and 2022 (two years), were selected for analysis. Only original research articles were included in the analysis. Articles were analysed based on authorship, corresponding authorship, and research centres within the South Asian Association for Regional Cooperation (SAARC) region (Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka). The main research topics were also examined. This data was recorded on Microsoft excel sheet and then descriptive analysis were calculated.
    Results: Of the total 4952 articles reviewed, 208 (4.2%) had authorship from the SAARC region. Of the 38079 authors in total, 1133 (2.97%) were from the SAARC region and 715 (63.1%) were male. The authors from India contributed the most (n=1074, 94.8%) articles. Of the 155 corresponding authors from SAARC, 150 (96.78%) were from India. Research centres from India were the leading contributors, (n=166, 93.26%). Out of all the publications, medical retina accounted for 1546 (31.22%) of the total articles.
    Conclusions: Compared to its share of the world's population, the SAARC region's research contribution to the top twenty ophthalmology journals is nominal.
    Keywords:  Authorship; Bibliometric analysis; Ophthalmology; Peer Review; Publications; Research priority; South Asia
    DOI:  https://doi.org/10.12669/pjms.41.2.10581
  21. Sleep Breath. 2025 Feb 11. 29(1): 98
    The impact of social media on sleep journals: analyzing the correlation between altmetrics and citation count.
    Salman Hussain, Raisa Chowdhury, Yaqoub Sharhan, Hamad Almhanedi, Mohammed Alterki, Abdulmohsen Alterki, Mohamed Abdelwahab.
       PURPOSE: The assessment of scientific articles is essential for making informed decisions regarding promotion, tenure, and funding, as well as for identifying influential research within a specific field. Traditional metrics like citation count have been the standard for evaluating the reach and influence of publications, but they have limitations. A new web-based metric-the Altmetric Attention Score (AAS)-offers a dynamic analysis of online engagement through social media platforms, including X (Formerly Twitter), Facebook, and YouTube. This study primarily examines the role of X activity in shaping AAS and explores its correlation with traditional citation counts in sleep medicine journals.
    METHODS: The study included articles from the top 10 sleep journals ranked by impact factor, focusing on articles published in 2020 and 2021. Data on citation counts were extracted from Journal Citation Reports (JCR), while AAS data were retrieved from the Altmetrics website. The analysis primarily focused on X activity as a proxy for online engagement. Pearson's and Spearman's correlations were used to evaluate the relationship between AAS, citation counts, and X activity. Statistical analysis was conducted using R software.
    RESULTS: A total of 3,944 articles were analyzed. The average AAS was 20, with a median of 2. A weak but statistically significant positive correlation (r = 0.22, P < 0.001) was observed between AAS and citation counts. X activity showed a strong correlation with AAS (r = 0.65, P < 0.001), but only a weak correlation with citation counts (r = 0.16, P < 0.001).
    CONCLUSION: This study highlights the strong relationship between X activity and AAS, emphasizing X's role in influencing Altmetric scores. However, the weaker correlation between AAS and citation counts implies that while AAS may measure immediate online attention, it is not always a reliable predictor of long-term academic impact.
    Keywords:  Ent; Medicine; Sleep; Social media
    DOI:  https://doi.org/10.1007/s11325-025-03274-7
  22. Clin Transl Sci. 2025 Feb;18(2): e70157
    Global Trends in the Value of Author Order Across Medical Publications: A Cross-Sectional Bibliometric Study.
    Hidenori Hashimoto, Miwa Sekine, Yuji Nishizaki, David Aune, Atsushi Mizuno, Yasuhiro Homma, Yasuhiko Kiyama, Shoji Sanada, Shigeki Aoki.
      This study aimed to analyse the value of author order across countries, within the 'Medicine General Internal' and 'Surgery' fields, to enhance transparency and fairness in academic evaluations, particularly in international collaborative research. A cross-sectional bibliometric study was conducted using data from 2,845,748 papers published in 2022 across over 18,000 journals listed on Web of Science. The study focused on 124,736 papers from the 'Medicine General Internal' and 'Surgery' fields published in the top 19 countries. The analysis examined the position of the corresponding author relative to other co-authors by country and specialty. Hierarchical clustering was applied to identify patterns and group countries based on author order. Three distinct clusters were identified with regard to the corresponding author's position. In Cluster A (South Korea, China and Taiwan), the corresponding author was often the last author. In Cluster B (India, Japan, Italy, Türkiye and Spain), the corresponding author was frequently the second author. Cluster C (the United States, England and Germany) included countries where the corresponding author was typically the first author. The findings underscore the need for clear, internationally accepted author order standards. Establishing such standards is crucial for promoting fairness, transparency and efficiency in international collaborative research and for ensuring equitable scientific communication.
    Keywords:  author order; bibliometric analysis; corresponding author; hierarchical clustering
    DOI:  https://doi.org/10.1111/cts.70157
  23. F1000Res. 2023 ;12 76
    Online marketing and brand awareness for HEI: A review and bibliometric analysis.
    Sailaja Bohara, Vashali Bisht, Pradeep Suri, Diksha Panwar, Jyoti Sharma.
       Background: This study conducted a comprehensive bibliometric analysis to identify the gaps in the existing literature related to Online marketing and brand awareness strategies for HEI. It has evaluated the current state of the literature on the given topic showing the pivotal role of online marketing and brand awareness in higher education for enrollment.
    Methods: The study used a web-based application, Biblioshiny, which comes in the bibliometrix package. The study used the Scopus database to create the data set, given its conventional construction and quality of the sources. The analysis done is descriptive. By using the bibliometrix software, the study showed the authors name, articles, sources, citations, relevant journals and co-citation from the year 2017 to 2022. The time period selected by the study was five years which means that articles published from 2017 to 2022 have been taken for the study.
    Results: We found that HEI online marketing and brand awareness have not been explored much as it has not reached the stage of maturity. Most of the publication was done during the time of Covid-19. Also, the role of brand awareness in student enrollment decisions for HEI requires more investigation. Top most publications their sources and top authors are identified.
    Conclusions: Bibliometric analysis has provided valuable insights into the seminal work, emerging trends, and the gap in the study. This area of study has been explored but not as much as challenges, and the effectiveness of online marketing tools like seo, sem,ppc and more has not been measured. Further, this paper allows researchers to study by examining the pattern of publications by seeing the different authorships, co-authors, collaborations, relevant sources, and citations. The insights of this paper will help education policymakers devise more creative strategies to increase enrollment, ensuring sustained relevance and competitive advantage in higher education institutions .
    Keywords:  Bibliometrix; Brand awareness; Enrollment; Higher education institutions; Online marketing; Science mapping; Technology; analysis
    DOI:  https://doi.org/10.12688/f1000research.127026.2
  24. An Acad Bras Cienc. 2025 ;pii: S0001-37652025000100701. [Epub ahead of print]97(1): e20241035
    A general analysis of the impact of international collaboration on the citation indices of scientific publications from 60 institutions across five continents.
    Iraine Duarte, Hellen G G Santos, Marcio L Rodrigues.
      Several studies suggest that international collaboration increases the impact of science. In this study, we selected 50 universities and 10 research institutes to analyze whether publications produced over a 10-year period would gain more visibility through the occurrence of international collaboration. To address this question, we selected the top 10 ranked universities in the world (2023), along with the top-ranked universities in Africa, Asia, Latin America, and Oceania. Additionally, we included 10 research institutes from different areas of the globe in our analysis. The percentage of publications including international collaboration varied widely among these institutions. Analysis of the average number of citations per publication, in addition to the determination of the field-weighted citation impact, confirmed that international collaboration resulted in higher citation indices. Our study employed approaches to partially quantify the influence of international collaboration on the impact of science, which could serve as the basis for scientific policies aimed at stimulating international partnerships and increasing scientific visibility.
    DOI:  https://doi.org/10.1590/0001-3765202520241035
  25. Clin Exp Optom. 2025 Feb 11. 1-9
    In vivo confocal microscopy in ophthalmology: research trends from a bibliometric analysis.
    Bedia Kesimal, Sücattin İlker Kocamış.
       CLINICAL RELEVANCE: In vivo confocal microscopy (IVCM) is a pivotal imaging tool in ophthalmology, enabling the non-invasive, real-time visualisation of corneal microstructures. Its clinical importance lies in its ability to diagnose and monitor a wide range of corneal and ocular surface conditions at a cellular level, enhancing early detection and treatment outcomes.
    BACKGROUND: IVCM enables detailed visualisation of corneal structures and has broad applications in diagnosing and managing corneal and ocular surface diseases. Despite its widespread use, no global bibliometric analysis of IVCM research in ophthalmology has been conducted to date. This study aims to bridge this gap by identifying influential articles, authors, institutions, and emerging trends in IVCM research.
    METHODS: A bibliometric analysis was conducted using the Web of Science Core Collection database. Articles and reviews in the ophthalmology research area were identified by searching for 'confocal microscopy' within titles and author keywords. Sub-analyses focused on corneal nerves and immune cells. Data were visualised using VOSviewer to create overlay visualisation maps, highlighting research trends and connections.
    RESULTS: A total of 1,389 articles were identified, with 600 published in the last decade. Corneal nerve studies constituted 425 publications, with an h-index of 68 and 38.81 citations per article. Immune cell studies accounted for 182 publications, with an h-index of 36 and 25.79 citations per article. The United States, China, and Italy were the most productive countries, while Harvard Medical School and the Massachusetts Eye and Ear Department of Ophthalmology led institutional output. Emerging keywords included 'limbal stem cell deficiency', 'deep learning', and 'artificial intelligence'.
    CONCLUSIONS: This study underscores the increasing impact and versatility of IVCM in ophthalmology. The findings highlight key contributors and trends, providing a roadmap for future research. The integration of artificial intelligence and novel analytical techniques will likely drive further advancements, enhancing the diagnostic and therapeutic potential of IVCM.
    Keywords:  Artificial intelligence; bibliometric analysis; corneal nerves; immune cells; in vivo confocal microscopy; ocular surface diseases
    DOI:  https://doi.org/10.1080/08164622.2025.2459345
  26. Discov Oncol. 2025 Feb 10. 16(1): 146
    A bibliometric analysis of immune response in oral cancer.
    Rongrong Zhang, Runying Guo, Yuqi Xin, Qingkun Jiang, Jiaxuan Qiu.
       BACKGROUND: Oral squamous cell carcinoma (OSCC), a type of oral cancer, has a high mortality rate and unfavorable outcomes. Its tumor microenvironment (TME) is intricate and adaptable, with research frequently focusing on the immune reaction. Scholars are exploring ways to enhance survival by bolstering the immune response within the TME. However, a comprehensive trend analysis is lacking. Bibliometric analysis can address this by visualizing research patterns. This study aimed to map these trends in OSCC immunology from 2003 to 2023.
    METHODS: An immunology-focused search on OSCC was executed within the Web of Science Core Collection, spanning 2003 to 2023. Despite its narrow focus, the search offers a telling glimpse of current researches in this domain. Bibliometric analysis was performed using VOSviewer, Citespace, Scimago Graphica, and R software.
    RESULTS: From 2003 to 2023, the field has published 805 publications, predominantly from China and the United States. The most valuable contributing author is Friedman Jay, topping co-citation counts. The journal Oral Oncology is the leading journal with the highest publication volume. An analysis of keyword bursts indicated that research into nivolumab and chemotherapy is a prevalent area of interest within the clinical community. These findings suggest that neoadjuvant immunotherapy represents a promising avenue for future therapeutic development.
    CONCLUSIONS: This study presented a summary of the current trends and research frontiers in the field of immunological aspects of OSCC. This summary can serve as a valuable reference and a source of new insights into this area of research.
    Keywords:  Bibliometric analysis; Chemotherapy; Neoadjuvant immunotherapy; Nivolumab; OSCC (Oral squamous cell carcinoma); Oral cancer; Tumor microenvironment
    DOI:  https://doi.org/10.1007/s12672-025-01912-w
  27. Healthcare (Basel). 2025 Jan 21. pii: 209. [Epub ahead of print]13(3):
    Hotspots and Trends in Research on Mental Health of the Rural Elderly: A Bibliometric Analysis Using CiteSpace.
    Yinzhu Hao, Lei Yang.
       BACKGROUND: This study addresses the need for a systematic analysis of research trends and hotspots in the mental health of rural elderly populations, a field that has gained increasing attention due to the growing global aging population. The previous literature has explored specific issues such as loneliness, depression, and social support, and yet a comprehensive review of research development, key themes, and gaps remains lacking.
    METHODS: Using CiteSpace software (CiteSpace 6.3.R1), this study conducts a bibliometric analysis of 1545 articles from the Web of Science Core Collection and 1793 articles from the China National Knowledge Infrastructure. The analysis identifies key themes, collaboration networks, and the evolution of research focus over time.
    RESULTS: The results reveal that while Chinese research in this field is highly active and diverse, international collaboration is limited, underscoring the need for stronger global partnerships.
    CONCLUSIONS: Emerging research areas, such as the impact of socioeconomic factors, intergenerational support, and rural healthcare policies, are identified. These findings provide valuable insights into the current state of research and highlight opportunities for future studies and policy-making aimed at improving the mental health and quality of life of rural elderly populations worldwide.
    Keywords:  CiteSpace; bibliometric analysis; mental health; rural elderly
    DOI:  https://doi.org/10.3390/healthcare13030209
  28. Front Med (Lausanne). 2025 ;12 1515853
    Global research trends on gastrointestinal cancer and mental health (2004-2024): a bibliographic study.
    Wenjin Han, Tianmeng Wang, Zhiqiang He, Caihua Wang, Zhaozhao Hui, Shuangyan Lei, Nan Hao, Ning Li, Xiaoqin Wang.
       Background: Gastrointestinal (GI) cancers impose a significant burden on global public health. Patients often experience mental health challenges due to physical changes and treatment-related symptoms, which can worsen their condition or delay recovery. Although research is mounting in this field, visual bibliometric analysis has not yet been conducted. This study aims to reveal the research hotspots and frontiers in this field using bibliometrics to guide future research.
    Methods: The publications on GI cancer and mental health were retrieved in the Web of Science Core Collection from 2004 to 2024. VOS Viewer and CiteSpace, as commonly used bibliometric analysis tools, were employed to visualize the network structure of bibliometric data and uncover the evolving trends in scientific research fields. VOS Viewer was used to identify keyword co-occurrences, while CiteSpace was utilized to generate network visualizations, produce dual-map overlays of journals, and perform burst keyword analysis.
    Results: A total of 1,118 publications were included for analysis. China had the highest number of publications in this field (341, 30.5%), while the United States held a central position (centrality = 0.48). The most productive author and institution were Floortje Mols and Tilburg University, respectively. Keyword analysis highlighted that "quality of life" (QoL) is a prominent research topic in the field, while "complications," "cancer-related fatigue," (CRF) "chronic stress," and "epidemiology" have been identified as key areas for future research.
    Conclusion: Research interest in this field continues to grow. The research direction is mainly focused on personalized mental health interventions to improve QoL, as well as preoperative mental healthcare and ongoing care through internet-based multidisciplinary collaboration to reduce postoperative complications. More detailed clinical symptom assessment is needed to distinguish between CRF and mental health issues and to provide targeted intervention measures in the future. The mechanism of mental health effects on the occurrence and development of GI cancer will be a frontier.
    Keywords:  bibliometric analysis; frontiers; gastrointestinal cancer; mental health; visualization
    DOI:  https://doi.org/10.3389/fmed.2025.1515853
  29. Front Surg. 2024 ;11 1505155
    Current update on surgical management for spinal tuberculosis: a scientific mapping of worldwide publications.
    Romaniyanto Romaniyanto, Muhana Fawwazy Ilyas, Aldebaran Lado, Daffa Sadewa, Dykall Naf'an Dzikri, Enrico Ananda Budiono.
       Introduction: Spinal tuberculosis (TB), or Pott's disease, remains a significant global health issue, particularly in regions with high TB prevalence. Despite antitubercular drug therapy being the primary treatment, surgical intervention is often required in cases of spinal instability or neurological complications. This study aims to conduct a comprehensive bibliometric analysis of worldwide publications related to the surgical management of spinal TB and to compare contributions from orthopaedic surgery and neurosurgery in this field.
    Methods: A bibliometric analysis was performed using data from the Scopus database, covering publications from 1896 to 2024. The search strategy focused on terms related to spinal TB and surgical interventions. The analysis included 1,857 publications, which were examined for trends, key contributors, and the evolution of surgical techniques. Metrics such as the number of publications, leading authors, affiliations, countries, and funding sponsors were compared between orthopaedic surgery and neurosurgery.
    Results: This study identified a steady increase in the number of publications over time. Key topics evolved from basic surgical methods, including early spinal procedures, to integrating pharmacological approaches alongside surgical techniques, such as antitubercular drugs, advancing into imaging research and procedure research involving refined surgical methods like spinal fusion. The recent phase reflects a shift towards technology-driven approaches, including minimally invasive techniques, artificial intelligence, and machine learning. China emerged as the leading country with the most contributions based on author, affiliations, funding sponsors, and countries. Last, orthopaedic surgery had more publications (274) than neurosurgery (96).
    Discussion: In conclusion, spinal TB surgery has evolved significantly, with a notable shift towards advanced, technology-driven approaches. Orthopaedic surgery leads in research output compared to neurosurgery. This bibliometric analysis provides valuable insights into the global research landscape, guiding future studies in the management of spinal TB.
    Keywords:  bibliometrics; neurosurgery; operative; orthopaedics; scientific mapping; spinal fusion; spinal tuberculosis; surgery
    DOI:  https://doi.org/10.3389/fsurg.2024.1505155
  30. Animals (Basel). 2025 Jan 27. pii: 368. [Epub ahead of print]15(3):
    Trends in the Application of Citizen Science in Waterbird Conservation: A Bibliometric Analysis.
    Ruilin Wang, Keming Ma.
      Waterbirds serve as indicator species for the quality and health of wetland ecosystems, and their conservation is of critical significance for global biodiversity. Citizen science has gradually emerged in recent years, playing an increasingly positive role in scientific research, particularly in ornithological studies. However, a systematic description of the application of citizen science data in waterbird conservation remains lacking. Bibliometrics is an effective method for analyzing the development of scientific disciplines, exploring trends, and examining thematic evolution. This paper utilizes bibliometric analysis of citation data from the Web of Science database, covering the period from 1970 to September 2024. The analysis reveals that this research field has undergone three distinct developmental phases, with a significant increase in annual publication volume during the third phase. Research focus has shifted from specific species and types of waterbirds to key hotspots and ecological phenomena. Future research hotspots are expected to include migratory birds, China, citizen science, and biodiversity. Influential papers within the field emphasize that the primary focus of waterbird conservation is habitat protection and the construction of habitat networks. As the discipline has developed, there is growing recognition that increasing public awareness of waterbird conservation, starting with student education, plays a crucial role in the accumulation of citizen science data and the advancement of waterbird conservation efforts.
    Keywords:  bibliometric; citizen science; trends; waterbird conservation
    DOI:  https://doi.org/10.3390/ani15030368
  31. J Multidiscip Healthc. 2025 ;18 697-710
    Global Research Trends and Focus on the Link Between Heart Failure and NLRP3 Inflammasome: A Bibliometric Analysis From 2010 to 2024.
    YanJie Lian, Heyi Zhang, Wenlong Xing, Sinai Li, Xiaolei Lai, Sihan Jia, JuJu Shang, Hongxu Liu.
       Background: Heart failure (HF) is characterized by elevated morbidity, mortality, and rehospitalization frequencies. This condition imposes a considerable medical burden and fiscal strain on society. Inflammation plays a crucial role in the inception, advancement, and outcome of HF. Despite mounting evidence demonstrating the pivotal function of the NLRP3 inflammasome in HF, a thorough bibliometric examination of research focal points and trajectories in this domain has yet to be undertaken.
    Methods: Publications related to the NLRP3 inflammasome in HF were retrieved from the Web of Science database spanning 2010-2024. The acquired data were subsequently analyzed utilizing various visualization instruments, including Citespace, VOSviewer, Scimago Graphica, and Microsoft Office Excel 2021.
    Results: A total of 282 papers were included in the analysis, authored by 2,130 researchers from 500 institutions across 34 nations/regions. China emerged as a significant contributor to this field, producing the highest number of outputs. Antonio Abbate was identified as the most prolific author. Virginia Commonwealth University and Wuhan University were the institutions with the highest publication output. INTERNATIONAL IMMUNOPHARMACOLOGY was the periodical with the most numerous publications in this sphere. CIRCULATION, however, received the highest number of citations, indicating its substantial influence on investigations in this field. Contemporary research focal points primarily concentrate on the activation and inhibition pathways of the NLRP3 inflammasome, the exploration of novel HF targets, and the association between HF and mitochondrial function. Future research trajectories are likely to encompass investigations into the relationship between HF and pyroptosis, as well as clinical studies on pharmaceuticals targeting the NLRP3 inflammasome as a therapeutic approach for HF.
    Conclusion: This investigation provides a comprehensive bibliometric analysis and synopsis of NLRP3 inflammable-related studies in HF. The findings offer a conceptual foundation for further research on the NLRP3 inflammasome in HF and provide valuable guidance for future research directions in this domain.
    Keywords:  NLRP3; heart failure; inflammasome; visualization analysis
    DOI:  https://doi.org/10.2147/JMDH.S505356
  32. J Insect Physiol. 2025 Feb 09. pii: S0022-1910(25)00008-3. [Epub ahead of print] 104754
    Trends and emerging hotspots in RNAi-based arthropod pest control: A comprehensive bibliometric analysis.
    Wenbin Liu, Xinyu Wang, Anmo Zhou, Junyu Zhang, Xinyu Ge, Bernard Moussian, Chuncai Yan, Shaobo Gao, Yiwen Wang.
      RNA interference (RNAi)-based pest control has emerged as a cutting-edge and highly promising approach in pest control, especially for insect pests, due to its advantages of reduced environmental risk, degradability, and good selectivity. This study provides a bibliometric analysis of RNAi-based pest control, evaluating the global scientific output in this field from the Web of Science Core Collection (WoSCC) and PubMed. From 2007, when the first RNAi-based Arthropod pest control strategy suited for field application was published, to August 2024, 722 English research articles were identified, focusing only on dsRNA delivery modes including feeding, soaking, and spraying, which hold high potential for field application. Articles examining gene function and potential targets by dsRNA injection were excluded. The 722 eligible articles were published in 132 journals by 3112 authors from 563 institutions in fifty countries. Over these 17 years, the number of publications on RNAi-based pest control has shown a trend of accelerating growth. PEST MANAGEMENT SCIENCE published the most articles, followed by PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, SCIENTIFIC REPORTS. China produced most articles, followed by the United States. However, China is significantly behind the United States in developing commercial products in this field. Hot target insects in RNAi-based pest control research included Bemisia tabaci, Helicoverpa armigera, Aphis gossypii Glover, Leptinotarsa decemlineata, and Diabrotica virgifera virgifera. Frequently studied target genes included vATPaseA, CHS1, SNF7, EcR and β-actin, ect. In recent years, various advanced technologies for dsRNA delivery have been developed and utilized in RNAi-based pest control system, including nanoparticle-enabled, symbiont-mediated, and plant-mediated deliveries. This study represents the first comprehensive analysis based on bibliometric methods, aiming to investigate the forefront hotspots and research trends of RNAi-based pest control, providing valuable references for researchers and developers in this field.
    Keywords:  Bibliometric analysis; Delivery system; Insecticide targets; RNAi-based insecticides; RNAi-based pest control
    DOI:  https://doi.org/10.1016/j.jinsphys.2025.104754
  33. J Perianesth Nurs. 2025 Feb 12. pii: S1089-9472(24)00529-X. [Epub ahead of print]
    Postoperative Thirst in Surgical Patients: A Bibliometric Study.
    Hatice Özsoy, Askeri Çankaya, Esra Özkan, Meryem Yavuz van Giersbergen.
       PURPOSE: Thirst during surgical intervention is an important parameter that may affect the clinical course of patients. In this context, although there is a large body of knowledge in the existing literature on thirst during the surgical period, the lack of bibliometric analysis on this subject is striking. This study aims to systematically evaluate scientific publications on thirst during the surgical period, to fill the gaps in the literature, and to provide new perspectives that can guide clinical practice.
    DESIGN: Descriptive and bibliometric analyses were used.
    METHODS: The study universe consisted of 256 articles on postoperative thirst in the SCOPUS database. The study data were analyzed with Excel and they were visualized with VOSviewer and Bibliometrix Package in R software.
    FINDINGS: In the study, it was determined that the 256 articles identified were published in 181 different sources between 1969 and 2024, with a total of 1,194 authors contributing to these articles. In this research area, the top 3 publishing countries, China (111) has the highest productivity, followed by the United States (67) and Brazil (52). Most of the articles were published in "Journal of Perianesthesia Nursing," "British Journal of Anesthesia," and "Acta Anaesthesiologica Scandinavica."
    CONCLUSIONS: The year and forecast analysis show that the number of studies on thirst, which is an important problem among surgical patients, has increased and will increase in the coming years. The increasing interest in thirst as an important problem among surgical patients shows that the interest and demand for research in this field are increasing.
    Keywords:  bibliometrics; patient; postoperative period; surgery; thirst
    DOI:  https://doi.org/10.1016/j.jopan.2024.10.020
  34. Naunyn Schmiedebergs Arch Pharmacol. 2025 Feb 14.
    Research progress of TRPV4 in pain over the past 20 years: a bibliometric analysis.
    Lele Huang, Qiwen Xuan, Ying Li, Jinghui Huang, Fanfu Fang.
      This study aims to explore the research hotspots and future research trends of transient receptor potential vanilloid 4 (TRPV4) in pain over the past two decades, with the objective of gaining insight into the development direction and focus of this field. A total of 791 articles were included in this study by searching the Web of Science Core Collection (WOSCC) database. To enhance research quality and accuracy, keywords with similar meanings were combined to eliminate ambiguity. Data visualization analysis was conducted using CiteSpace and VOSviewer, encompassing the examination of countries, research institutions, authors, journals, keywords, references, and categories. Over the past 20 years, 791 scientific articles on TRPV4 and pain have been reviewed, originating from 52 countries, involving 885 research units, 4121 authors, and published in 332 journals. The United States, China, and Japan emerged as core contributors in this field. Prominent research institutions include Duke University (United States) and the University of California, San Francisco (United States). The most prolific researchers include Liedtke, Wolfgang (United States), Bunnett, Nigel W. (United States), and Yue, Shou-wei (China). Research on TRPV4 and pain predominantly focuses on the molecular mechanisms, role of pain models, drug development, and clinical applications, aimed at advancing pain treatment. This study provides a comprehensive overview of the literature on TRPV4 and pain over the past two decades, offering researchers and scholars fresh insights into the field's development trends and future directions.
    Keywords:  Bibliometric analysis; CiteSpace; Pain; TRPV4; VOSviewer
    DOI:  https://doi.org/10.1007/s00210-025-03846-0
  35. Nutrients. 2025 Jan 22. pii: 399. [Epub ahead of print]17(3):
    Mapping the Scientific Research on Nutrition and Mental Health: A Bibliometric Analysis.
    Ramona Hiltensperger, Jennifer Neher, Lea Böhm, Annabel Sandra Mueller-Stierlin.
       BACKGROUND/OBJECTIVES: The connection between nutrition and mental health has become a point of growing interest. In response, nutritional psychiatry research has emerged as a field dedicated to understanding these interactions. A bibliometric analysis was conducted to map the growth and trends in this area, providing insights into its evolving scope and key research contributions.
    METHODS: A literature search was conducted within the Web of Science Core Collection. Data analysis was performed using the result analysis and citation report options of Web of Science as well as the visualization software VOSviewer (Version 1.6.20).
    RESULTS: A total of 31,556 articles on nutrition and mental health were published from 2000 to 2024 across various WoS categories, mainly in "Psychiatry", "Public, Environmental & Occupational Health", and "Nutrition & Dietetics". The most prolific research groups are based in North America. Recent publications mainly cover seven clusters: (1) public health and social factors, (2) interventions and biological mechanisms, (3) the health of the elderly, (4) nutrition-related illnesses, (5) lifestyle behavior, (6) observational studies, and (7) pregnancy and the postpartum period.
    CONCLUSIONS: In view of the increasing research activities and growing allocation of resources in nutritional psychiatry research, it is important to define research priorities in close collaboration with service users and stakeholders. Research should be approached in a holistic manner through multidisciplinary research consortia to ensure comprehensive and impactful outcomes.
    Keywords:  bibliometric analysis; mental health; nutrition; psychiatry
    DOI:  https://doi.org/10.3390/nu17030399
  36. J Immunol Res. 2025 ;2025 3393342
    Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis.
    Jiaona Xu, Yinan Yu, Shijie Li, Fanghui Qiu.
      Amino acid metabolism in T cells determines the therapeutic efficacy of T-cell-targeting drugs. To assess the direction of amino acid metabolism in T cells and construct related knowledge structure, we performed a bibliometric analysis aiming at amino acid metabolism in T cells utilizing studies publicized in recent 15 years. Three hundred thirty-seven related studies were downloaded from the Web of Science Core Collection (WoSCC), and the information on countries, institutes, and authors was collected and analyzed. In addition, the present research status and future trends were explored according to the results yielded from the analysis of cited references and keywords. This study revealed that publications regarding amino acid metabolism in T cells gradually increased each year. The USA is the top producer and most influential country in this field. Recent research has focused on the correlation between the metabolism of several amino acids and regulatory T cells (Tregs) and CD8+ T cells. Overall, this research offers a comprehensive exhibition on the field of amino acid metabolism in T cells, which will help researchers to study this domain more effectively and intuitively.
    Keywords:  T lymphocytes; VOSviewer; amino acid metabolism; bibliometric; citespace
    DOI:  https://doi.org/10.1155/jimr/3393342
  37. Acta Psychol (Amst). 2025 Feb 11. pii: S0001-6918(25)00094-0. [Epub ahead of print]254 104781
    Research trends and hotspots in post-stroke speech rehabilitation: A bibliometric analysis.
    Nan Huang, Kang Zou, Fang Liu, Zhen Su, Long Chen, Yanbiao Zhong, Yun Luo, Maoyuan Wang, Li Xiao.
       BACKGROUND: With the global population aging, the incidence of stroke is rising, often resulting in motor dysfunction, speech disorders, and swallowing difficulties, significantly affecting daily life and social participation. Speech and language disorders notably impair communication and restrict social engagement, making speech rehabilitation a critical intervention. However, comprehensive bibliometric analyses on post-stroke language rehabilitation are limited, restricting understanding of progress in this field.
    OBJECTIVE: This study aimed to identify hotspots and trends in post-stroke speech rehabilitation research from 2003 to 2023 to guide future studies.
    METHODS: Articles on post-stroke speech rehabilitation from 2003 to 2023 were retrieved from the Web of Science Core Collection. Analyses included annual publications, key authors, countries, institutions, journals, co-citations, and keywords.
    RESULTS: Among 1077 articles, publication volume showed an upward trend, with the United States leading in contributions. The Aphasiology journal published the most articles, and prominent institutions like the University of Queensland demonstrated significant publication and citation impact. Key trends included "communication disorders," "functional connectivity," and "melodic intonation therapy," with "stroke" and "aphasia" emerging as central keywords.
    CONCLUSION: Research in post-stroke speech rehabilitation is increasing, with significant contributions from the United States and key institutions. Trends highlight the importance of communication-focused therapies and innovative techniques like melodic intonation therapy. This study provides insights into research directions.
    Keywords:  Aphasia; Bibliometrics; Rehabilitation; Speech rehabilitation; Stroke; Therapy
    DOI:  https://doi.org/10.1016/j.actpsy.2025.104781
  38. J Environ Manage. 2025 Feb 08. pii: S0301-4797(25)00423-2. [Epub ahead of print]376 124447
    Carbon reduction and green finance innovations: A scientometric analysis using bibliometrics and DTM model.
    Tian Xie, Chenpeng Yang, Yaoyao Wei, Guiye Dai.
      As an emerging financial concept and practice, green finance has the potential to effectively promote carbon reduction. This study proposes a four-stage systematic analysis framework which employs bibliometric theory, Dynamic Topic Models (DTM), and regression analysis. Based on 598 literature from the WOS core database, we comprehensively analyze green finance innovations triggered by carbon reduction. It identifies the basic data characteristics of scientific innovation in this field, the co-citation network of literature and the distribution of research hotspots, and it predicts important themes and directions for future research. The results show that there was a surge in the number of publications in recent years, indicating a new field of research on Carbon Reduction Triggered Green Finance (CRTGF) is gradually forming. China, the United States, and the United Kingdom are the top three countries in terms of publication volume, demonstrating their leading role in the green finance field and their significant contribution to global carbon reduction. The research hotspots and trends in the future mainly boiled down to three aspects: green finance technology innovation for carbon reduction, green finance policy innovation for carbon reduction, and green finance tool innovation for carbon reduction. This study offers a comprehensive overview of CRTGF research, providing researchers with a comprehensive understanding of the field and a framework for future research directions.
    Keywords:  Bibliometrics; Carbon reduction; CiteSpace; DTM; Green finance
    DOI:  https://doi.org/10.1016/j.jenvman.2025.124447
  39. Infection. 2025 Feb 11.
    Panoramic quantitative and visualization-based bibliometric analysis of Mycoplasma pneumoniae.
    Jun Wang, Mo Wu, Mei Liu, Wenbin Tuo, Yu Shang, Yuxuan Tao, Tian Chen, Cong Yao, Zhen Xie, Yun Xiang, Qinzhen Cai, Chunhui Yuan.
       PURPOSE: Severe pneumonia, refractory pneumonia and extrapulmonary complications caused by mycoplasma pneumoniae infection were increasing, posing a serious threat to health. This study aimed to explore a breakthrough for further investigations in further.
    METHODS: The Web of Science Core Collection was queried using the search term TS = "mycoplasma pneumoniae" for articles from January 1, 2009, to September 24, 2024. Bibliometric indicators were analyzed using VOSviewer, Pajek, and Scimago Graphica, while CiteSpace was utilized for visual analyses, including the contributions of different countries/regions, institutions, authorship patterns, journals, co-citations, keywords, and genes.
    RESULTS: 3,093 articles were collected and showed an increase interest in MPP research. China was the most prolific contributor, and the USA demonstrated the strongest collaboration willingness. The USA and China had the highest cooperation frequency and closest research relationship. The UK had the highest single-article citation count. Fudan University had the greatest total link strength. The top keywords were "Mycoplasma Pneumoniae" and "community-acquired pneumonia", with "children" being particularly prominent throughout the literatures. "risk factors" and "plastic bronchitis" may represent emerging hotspots in MPP research. Antibiotic therapy, herpes simplex virus infections, and serology detection were the high interest surrounding topics over past decade. mNGS, severe community-acquired pneumonia, co-infections of adenovirus or RSV may become focal points in future. CRP and IL-17 A represented significant genes among MP infection. Positive regulation of cytokine production played a critical role in MP infection.
    CONCLUSION: This bibliometric analysis provides insights into its status, frontiers, and hotspots, offering essential guidance to address challenges in MP.
    Keywords:  Bibliometric analysis; Co-infection; Community-acquired pneumonia; IL-17A; Mycoplasma pneumoniae
    DOI:  https://doi.org/10.1007/s15010-025-02482-3
  40. Animals (Basel). 2025 Jan 30. pii: 390. [Epub ahead of print]15(3):
    Assessing Gender Equality in Italian Animal Science: A Case Study on Academic Careers and Research Outcomes.
    Anna Sandrucci, Lucia Bailoni, Paola Crepaldi.
      This paper focuses on gender issues within the Italian Animal Science and Production Association (ASPA), which includes both academic and non-academic researchers involved in animal sciences. Data from the association's archives in 2023 and bibliometric data obtained from Scopus and Web of Science were used. This study highlighted how within the ASPA and in that part of the academic realm falling within the field of animal science, a noticeable gender gap still exists, albeit decreasing over time at a very slow pace. There is clear vertical segregation, with a minority of women occupying full professor positions, and horizontal segregation with a low percentage of women involved in animal science disciplines closer to STEM fields, such as "Animal breeding and genetics". At the bibliometric level, gender differences in bibliometric indicators are observed, favouring men, although these differences are not significant when considering the academic position, scientific sector, and age. In the official journal of the ASPA (Italian Journal of Animal Science), women are under-represented in prestigious positions such as first, last, and corresponding authors. Scientific societies, academic institutions, and research organizations are called upon to do their part to accelerate the process of overcoming these inequalities.
    Keywords:  academic careers; authorship; bibliometrics; gender gap; segregation
    DOI:  https://doi.org/10.3390/ani15030390
  41. Recent Adv Inflamm Allergy Drug Discov. 2025 Feb 07.
    A Bibliometric Analysis on Urticaria: Roles of Oxidative Stress, Inflammation, Immunity, and Treatment Modalities.
    Hafiz Muhammad Zeeshan, Md Belal Bin Heyat, Arshiya Sultana, Mohd Ammar Bin Hayat, Eram Sayeed, Faijan Akhtar, Nouhayla Benkmil, Rashid Abbasi, Asmaa Sayed Abdelgeliel.
      This study provides a comprehensive bibliometric analysis of global research on urticaria, aiming to chart its progression, assess its relevance, and explore the roles of oxidative stress, inflammation, and immunity in its pathogenesis. Additionally, by analyzing data from PubMed and Scopus, we mapped research trends, identified leading authors and institutions, and examined global collaboration patterns. We also evaluated the impact of oxidative stress, inflammation, and immunity on urticaria and assessed the roles of both conventional and traditional medicine in its management. The results highlight the evolution of urticaria research, key contributors, thematic developments, and collaborative networks. This study offers a detailed bibliometric profile and thematic map, including insights into effective authors, prominent keywords, and significant research patterns. The findings are valuable for medical researchers, providing an updated overview of current themes and gaps, and are also beneficial for healthcare decision-makers by summarizing relevant information for strategic planning and fostering new collaborations. Additionally, the study integrates biological aspects related to urticaria with insights into traditional treatments, contributing to both research and practical management strategies.
    Keywords:  Etiopathogenesis; ROS; immunity; inflammation; management; oxidative stress; pubMed; scopus.; skin; treatment; unani medicine
    DOI:  https://doi.org/10.2174/0127722708352247250121110712
  42. Heliyon. 2025 Feb 15. 11(3): e42242
    Global research landscape and hotspots for ferroptosis in glioma: A comprehensive bibliometric and visual analysis.
    Xinyue Zheng, Mengyao Diao, Shan Tong, Shuo Yang, Jing Lin, Shenghua Zhuo, Ting Wang, Jian Dai, Shenbo Chen, Kai Wang.
      Studying ferroptosis is crucial for understanding the mechanisms underlying the onset and progression of glioblastoma, identifying therapeutic targets, and improving prognosis assessment and diagnostic methods. While recent research has explored the link between ferroptosis and glioblastoma, there is a lack of comprehensive bibliometric analyses specifically addressing this relationship and its connection to glioblastoma. To address this gap, we conducted a thorough analysis of 225 relevant articles on glioma and ferroptosis obtained from the Web of Science database covering the period from 2012 to 2023, employing rigorous exclusion criteria. Visual and statistical analyses were performed using CiteSpace, VOSviewer, R Studio Plotting, and Scimago Graphica Beta. Our findings revealed a significant exponential growth in the number of studies during the last decade. China, the United States, and Germany made the most substantial contributions to research in this field, collectively accounting for 76.2 % of the total research output. Notably, Central South University, Shandong University, and Zhejiang University emerged as leaders in both literature production and research collaboration. Frontiers in Oncology stood out as the most prolific journal, encompassing a wide array of topics from molecular mechanisms to potential therapeutic strategies. Visual keyword analysis highlighted "tumor biology" "cell death mechanisms" and "gene expression and metabolic processes" as central themes in the research network. This study offers a comprehensive visual perspective on the global publication landscape of ferroptosis in glioma, providing valuable insights for researchers seeking to understand the current state of the field and identify potential directions for future studies.
    Keywords:  Bibliometric analysis; Ferroptosis; Glioma; Visualization analysis; Web of science
    DOI:  https://doi.org/10.1016/j.heliyon.2025.e42242
  43. Brain Res Bull. 2025 Feb 11. pii: S0361-9230(25)00058-9. [Epub ahead of print]222 111246
    Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis.
    Donghai Wu, Siying Qu, Haiju Sun, Shuting Zhou, Xinyuan Qu, Yutian Chen, Hantong Hu, Xiaoyu Li.
      Depression is a common but serious mental health illness affected human's physiology and psychology. In contemporary times, neurophysiological research on depression has emerged as a prominent area of investigation, yet there remains a paucity of review elucidating the central mechanisms of depression in the brain. Consequently, we undertook a bibliometric analysis and visualization assessment to underscore recent advancements in research pertaining to the neural underpinnings of depression. By employing these methods, we have collected articles spanning the period from 2013 to 2024, shedding light on the latest insights into the brain mechanisms associated with depression. Bibliometric analysis found 16327 research papers in the field of brain mechanism underlying depression, overall showing a sustained growth trend. Through meticulous analysis of collected data on institutions and countries, authors, co-cited literature, keywords, etc., this paper humbly aims to tentatively identify future research hotspots and frontiers, hoping to modestly contribute to and stimulate further scholarly progress in the field.
    Keywords:  Bibliometric analysis; Brain mechanism; Citespace; Depression; VOSviewer
    DOI:  https://doi.org/10.1016/j.brainresbull.2025.111246
  44. Tissue Eng Part C Methods. 2025 Feb;31(2): 85-100
    Research Trends and Hot Topics of Nanozymes in Wound Care: A Bibliometric Analysis.
    Shuilan Bao, Yiren Wang, Yuxin Zhong, Shouying Chen, Li Yao, Yamei Luo, Ping Zhou, Yun Zhou.
      Nanozymes, as innovative enzyme mimics, hold significant promise for wound care, including antibacterial properties and tissue regeneration. Given their potential to transform wound management, this study utilizes advanced bibliometric tools to provide a comprehensive analysis of the nanozyme research landscape. The analysis covers various aspects, including publication trends, institutional contributions, journal coverage, and author involvement, offering a holistic view of research dynamics. It reveals the evolution of nanozyme research across different phases of wound healing by examining keyword co-occurrence frequencies and timeline developments. In addition, the study identifies emerging research clusters within these phases, focusing on three key areas: enhancing nanozyme performance, integrating them with hydrogel matrices, and developing responsiveness to external stimuli. These clusters highlight the increasing sophistication and diversity of nanozyme-based solutions for wound care. Furthermore, the study explores the intersection of nanozyme research with artificial intelligence (AI) and wearable sensors. This integration presents unprecedented opportunities for real-time monitoring, personalized treatment plans, and predictive analytics in wound care. The findings indicate a growing interest in this interdisciplinary field, pinpointing research frontiers centered around AI-driven wound assessment, continuous monitoring through wearable technologies, and the application of AI algorithms in nanozyme-based wound dressings. In summary, this bibliometric study provides a comprehensive global overview of research trends, key literature, hotspots, and emerging frontiers in nanozyme-based wound care. By investigating the synergy between AI, wearable sensors, and nanozymes, it elucidates the potential for novel and personalized treatment strategies in this rapidly advancing field.
    Keywords:  bibliometrics; citespace; nanomaterials; nanozymes; visualization; vosviewer; wound care
    DOI:  https://doi.org/10.1089/ten.tec.2024.0329
  45. J Neurosurg. 2025 Feb 14. 1-8
    Quantity versus quality: analysis of research publications in the 2023 neurosurgery match.
    Alexander F Wang, Ethan A Wetzel, Timothy R West, Logan Muzyka, Andreas C Runde, Ali M Nasser, Uyanga Batsaikhan, Ganesh M Shankar, Bryan D Choi, Brian V Nahed.
       OBJECTIVE: Prematch research productivity is a heavily utilized metric in evaluating neurosurgery residency applicants. With the rise in research output by successfully matched candidates and the so-called publication arms race, there is a growing interest in understanding the quality and impact of the research conducted by medical students who secure neurosurgery residency positions. This study aimed to characterize the research output of medical students who matched into neurosurgery in 2023, identify predictors of research productivity, and explore the implications of research output on match outcomes.
    METHODS: First-year neurosurgery residents from the 2023 match were identified via program websites. Research output data were collected from the PubMed and Scopus databases, excluding publications released after the 2023 National Resident Matching Program deadline. Predictive analyses were conducted using multiple linear regression models.
    RESULTS: Data were obtained for 242 1st-year neurosurgery residents and 2519 PubMed-indexed publications. The median numbers of total and first author publications were 7 (range 0-73) and 2 (range 0-25), respectively. The median number of citations was 28 (range 0-1010), with a median impact factor of 3.1 (range 0-30.43). Most publications represented retrospective clinical research (n = 839). Of the neurosurgery-related publications, spine-related research was most common (n = 410), while peripheral nerve research was the least common (n = 20). Factors associated with higher publication output included attending a top 20-ranked U.S. News & World Report medical school (p = 0.00044), international medical graduate status (p = 1.95e-6), and obtaining a doctor of philosophy degree (p = 0.00582). Applicants who published more than 30 papers averaged 4.16 citations per paper, whereas residents who published fewer than 30 papers averaged 8.34 citations per paper (p = 0.0006).
    CONCLUSIONS: This study characterizes the research output of successfully matched neurosurgery applicants and identifies medical school ranking and degree status as predictors of research productivity. Interestingly, only the rank of the medical school attended predicted better match outcomes despite an overall shift to utilizing research as a metric of merit in residency applications in reaction to an increase in pass/fail medical school curriculums and changes in United States Medical Licensing Examination Step 1 grading systems. These findings also demonstrate that residents who published the most papers published the lowest-impact research, which aligns with the notion that there is an increased emphasis on publication quantity rather than publication quality.
    Keywords:  arms race; medical education; neurosurgery; neurosurgical education; residency match
    DOI:  https://doi.org/10.3171/2024.10.JNS242070
  46. J Pak Med Assoc. 2025 Feb;75(2): 265-274
    Bibliometric analysis of the impacts of COVID-19 on the mental health of college students.
    Jianxiang Tian, Huilin Khan, Linshu Luo, Libo Dai, Junyu Pan.
      The current narrative review was planned to summarise research on the effects of coronavirus disease-2019 on the mental health of college students. A total of 1,695 studies from the Web of Science Core Collections database were accessed using VOSviewer software. China and the United States jointly contributed almost half of the overall publications, while the United States and the United Kingdom demonstrated the strongest collaborative network, and the University of Toronto was the research institution with the highest number of publications; 34(2%) papers and 2,330 citations. The current hotspots could be categorised into four areas, with stress, anxiety and depression being the most prominent. Those effects varied based on their academic major, gender, learning status and social support. The findings underscored the immediate need to cultivate international collaboration and interdisciplinary authorship, alongside the implementation of tailored preventive measures.
    Keywords:  Depression, Mental health, Pandemic, COVID-19, Bibliometrics, Anxiety.
    DOI:  https://doi.org/10.47391/JPMA.11284
  47. J Pharm Bioallied Sci. 2024 Dec;16(Suppl 4): S4114-S4116
    A Step-By-Step Guide of Bibliometric Study for Healthcare and Allied Research.
    Mukesh Kumar, Sommya Kumari, Sowmya Sree Guntipally, Ajay Chhabra, Ashok Kumar, Pankaj Kumar.
      Initially started in the arena of business research and management studies, bibliometric analysis has become increasingly popular in the speciality of medical and dental research recently. Bibliometric analysis is proven to be a precious tool in unraveling and visualizing the collective knowledge of scientific literatures and developmental details of recognized fields through the systematic interpretation of extensive amounts of unstructured data. It provides scholars with the ability to obtain a comprehensive overview, pinpoint areas lacking in knowledge, generate novel research philosophies, and apply planned outcomes within the field. Well-executed bibliometric studies can provide scholars with valuable insights, including a broad outline of the research field of interest, identification of research gaps, generation of new research philosophies, and positioning of their contributions. A notable gap exists in the availability of a comprehensive guiding principle for bibliometric analysis in medical/dental research, presenting a notable problem for researchers eager to enhance their understanding of this methodology.
    Keywords:  Analysis; bibliometry; research
    DOI:  https://doi.org/10.4103/jpbs.jpbs_1347_24
  48. Healthcare (Basel). 2025 Feb 02. pii: 305. [Epub ahead of print]13(3):
    A Bibliometric Analysis of Healthcare Intervention-Related Studies Reporting Patient and Public Involvement and Engagement.
    Wenze Lu, Yan Li, Jed Montayre, Mengqi Li, Ka Yan Ho, Jiaying Li, Janelle Yorke.
       BACKGROUND/OBJECTIVES: Patient and public involvement and engagement (PPIE) has gained global recognition as an innovative healthcare research practice. PPIE engages end-users throughout the research process, improving intervention effectiveness, resource efficiency, and user satisfaction. Despite its increasing inclusion in studies, comprehensive bibliometric reviews of healthcare intervention-related studies reporting PPIE are scarce. This study aims to conduct a bibliometric analysis of healthcare intervention-related studies reporting PPIE in recent decades to identify key worldwide bibliometric features, themes, and trends.
    METHODS: The analysis includes 10,624 relevant English articles published in the Web of Science (WoS) Core Collection up to 26 November 2024. Search terms were selected based on PPIE conceptualization, interventional types, and related healthcare terms. Using WoS descriptive analysis and CiteSpace, we examined bibliometric features and identified major international themes and trends.
    RESULTS: There has been a significant increase in the number of healthcare intervention-related studies reporting PPIE over the past five years, especially from the United States and the United Kingdom, with a recent rise in Asia. However, cross-national collaboration remains limited. Key research themes identified include "community participation", "health equity", "coronary heart disease", "web-based patient empowerment", "mental illness", and "obesity prevention", with growing interest in "mobile health" and "digital health".
    CONCLUSIONS: This study provides a comprehensive and up-to-date overview of the bibliometric characteristics and evolving trends in healthcare intervention-related studies reporting PPIE. It highlights global regions with limited PPIE implementation, suggests pathways for further development, and identifies key research themes. The study offers researchers and practitioners valuable insights into tracking PPIE trends in healthcare interventions and fostering collaborations on evidence-based PPIE studies with leading scholars and institutions worldwide. Additionally, the findings drive innovations aimed at improving patient and public healthcare outcomes.
    Keywords:  bibliometric review; healthcare; intervention; patient and public involvement and engagement; themes; trends
    DOI:  https://doi.org/10.3390/healthcare13030305
  49. J Infect Public Health. 2025 Jan 07. pii: S1876-0341(24)00381-2. [Epub ahead of print]18(4): 102647
    Scientometric analysis of research trends in hemorrhagic fever with renal syndrome: A historical review and network visualization.
    Bing Xu, Qian Yin, Danfeng Ren, Shaocong Mo, Tianzhi Ni, Shan Fu, Ze Zhang, Taotao Yan, Yingren Zhao, Jinfeng Liu, Yingli He.
       BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) research has undergone significant global transformation over the past decades. A comprehensive scientometric overview of research trends and scholarly cooperation in HFRS is absent. This study employs scientometric analysis to map the evolution of research themes, identify widely and scarcely explored areas, and anticipate future research directions.
    METHODS: We searched Web of Science Core Collection from inception until July 31, 2023, identifying 3908 HFRS-related studies published for analysis. Utilizing CiteSpace, VOSviewer, and Bibliometrix, we performed co-authorship, co-occurrence, and co-citation analyses, and visualized research networks.
    RESULTS: Our analysis revealed a consistent upward trend in HFRS publications since 1980, with an average growth rate of 11.34 %. The United States led in publication and citation counts, followed by China, Finland, Germany, and Sweden. Through co-occurrence analysis, we categorized keywords into eight clusters and 24 sub-clusters, revealing six predominant research themes: Clinical Features, Epidemiology, Mechanisms, Virus, Evolution, and Host. Notably, while themes such as Virus and Pathogenesis have been extensively studied, others, including certain aspects of Host research and Environmental Factors, remain less explored.
    CONCLUSION: This scientometric synthesis provides a global perspective on the breadth and depth of HFRS research, highlighting well-trodden and understudied areas. It offers a roadmap for researchers to navigate the evolving landscape of HFRS studies and prioritize areas ripe for future investigation.
    Keywords:  Hantavirus; Hemorrhagic fever with renal syndrome; Hotspot; Scientometric analysis; Visualization
    DOI:  https://doi.org/10.1016/j.jiph.2024.102647
  50. ACS Omega. 2025 Feb 04. 10(4): 3282-3303
    Recent Progress and Perspectives on Functional Materials and Technologies for Renewable Hydrogen Production.
    Mona Lisa M Oliveira, Camila M A C Alves, Carla F Andrade, Diana C S de Azevedo, Fernanda L Lobo, Araceli Fuerte, Paloma Ferreira-Aparicio, Concepción Caravaca, Rita X Valenzuela.
      Scientists worldwide have been inspecting hydrogen production routes and showing the importance of developing new functional materials in this domain. Numerous research articles have been published in the past few years, which require records and analysis for a comprehensive bibliometric and bibliographic review of low-carbon hydrogen production. Hence, a data set of 297 publications was selected after filtering journal papers published since 2010. The search keywords in the Scopus Database were "green hydrogen" and "low carbon hydrogen production and materials". The data were analyzed using the R Bibliometrix package. This analysis made it possible to determine the total annual publication rate and to segregate it by country, author, journal, and research institution. With a general upward trend in the total number of publications, China was identified as the leading country in research on the subject, followed by Germany and Korea. Keyword analysis and the chronological evolution of several important publications related to the topic showed the focus was on water splitting for low-carbon H2 production. Finally, this review provides future directions for technologies and functional materials for low-carbon hydrogen production.
    DOI:  https://doi.org/10.1021/acsomega.4c10407
  51. J Prosthet Dent. 2025 Feb 08. pii: S0022-3913(25)00003-4. [Epub ahead of print]
    Knowledge mapping and trends in implant-supported removable partial dentures.
    Isabela Reginaldo, Luciano José Pereira, Adriana Pinto Bezerra, Isabela Kendra Rodrigues Oliveira, Gabriella Reis, Bruno Manoel Medeiros E Silva, Luiz Otávio de Oliveira Pala, Thais Marques Simek Vega Gonçalves.
       STATEMENT OF PROBLEM: Implant-supported removable partial dentures (RPDs) are an effective treatment, but an overview of publication trends on this topic is lacking.
    PURPOSE: The purpose of this publication overview of implant-supported RPDs, focusing on study design, citations trends, journals impact factor, and literature gaps.
    MATERIAL AND METHODS: Data were retrieved from the Web of Science (WoSCC) until November 2024. Articles reporting clinical trials, case reports, in vitro studies, and reviews were included. Quantitative differences in impact factor and citations for retentive component and study designs were analyzed with 2-way ANOVA followed by Tukey HSD. Factors influencing citation counts were also considered with a Poisson regression model (α=.05).
    RESULTS: A total of 155 articles published from 1974 to 2024 were analyzed, showing a significant publication rise in the last decade (n=112; 72.3%). The impact factor ranged from 1.7 to 4.8, with prospective (n=49) and in vitro (n=40) studies the majority. Japan led in contributions (n=24), and the Journal of Prosthetic Dentistry (n=19) had the most articles. The citations number was influenced by study type and retentive component, with prospective and RCT studies and frictional components receiving the highest citations. No significant differences were found in impact factor (P>.05).
    CONCLUSIONS: Gaps exist regarding the long-term performance, function, and cost-benefit of implant-supported RPDs and more randomized clinical studies involving periodontal health, prosthesis complications, digital manufacturing, and treatment patients with Kennedy Classes III and IV are needed.
    DOI:  https://doi.org/10.1016/j.prosdent.2024.12.024
  52. JMIR Ment Health. 2025 Feb 10. 12 e64445
    Use of Digital Health Technologies for Dementia Care: Bibliometric Analysis and Report.
    Hebatullah Abdulazeem, Israel Júnior Borges do Nascimento, Ishanka Weerasekara, Amin Sharifan, Victor Grandi Bianco, Ciara Cunningham, Indunil Kularathne, Genevieve Deeken, Jerome de Barros, Brijesh Sathian, Lasse Østengaard, Frederique Lamontagne-Godwin, Joost van Hoof, Ledia Lazeri, Cassie Redlich, Hannah R Marston, Ryan Alistair Dos Santos, Natasha Azzopardi-Muscat, Yongjie Yon, David Novillo-Ortiz.
       BACKGROUND: Dementia is a syndrome that compromises neurocognitive functions of the individual and that is affecting 55 million individuals globally, as well as global health care systems, national economic systems, and family members.
    OBJECTIVE: This study aimed to determine the status quo of scientific production on use of digital health technologies (DHTs) to support (older) people living with dementia, their families, and care partners. In addition, our study aimed to map the current landscape of global research initiatives on DHTs on the prevention, diagnosis, treatment, and support of people living with dementia and their caregivers.
    METHODS: A bibliometric analysis was performed as part of a systematic review protocol using MEDLINE, Embase, Scopus, Epistemonikos, the Cochrane Database of Systematic Reviews, and Google Scholar for systematic and scoping reviews on DHTs and dementia up to February 21, 2024. Search terms included various forms of dementia and DHTs. Two independent reviewers conducted a 2-stage screening process with disagreements resolved by a third reviewer. Eligible reviews were then subjected to a bibliometric analysis using VOSviewer to evaluate document types, authorship, countries, institutions, journal sources, references, and keywords, creating social network maps to visualize emergent research trends.
    RESULTS: A total of 704 records met the inclusion criteria for bibliometric analysis. Most reviews were systematic, with a substantial number covering mobile health, telehealth, and computer-based cognitive interventions. Bibliometric analysis revealed that the Journal of Medical Internet Research had the highest number of reviews and citations. Researchers from 66 countries contributed, with the United Kingdom and the United States as the most prolific. Overall, the number of publications covering the intersection of DHTs and dementia has increased steadily over time. However, the diversity of reviews conducted on a single topic has resulted in duplicated scientific efforts. Our assessment of contributions from countries, institutions, and key stakeholders reveals significant trends and knowledge gaps, particularly highlighting the dominance of high-income countries in this research domain. Furthermore, our findings emphasize the critical importance of interdisciplinary, collaborative teams and offer clear directions for future research, especially in underrepresented regions.
    CONCLUSIONS: Our study shows a steady increase in dementia- and DHT-related publications, particularly in areas such as mobile health, virtual reality, artificial intelligence, and sensor-based technologies interventions. This increase underscores the importance of systematic approaches and interdisciplinary collaborations, while identifying knowledge gaps, especially in lower-income regions. It is crucial that researchers worldwide adhere to evidence-based medicine principles to avoid duplication of efforts. This analysis offers a valuable foundation for policy makers and academics, emphasizing the need for an international collaborative task force to address knowledge gaps and advance dementia care globally.
    TRIAL REGISTRATION: PROSPERO CRD42024511241; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=511241.
    Keywords:  bibliometric analysis; digital health technologies; evidence-based medicine; people living with dementia
    DOI:  https://doi.org/10.2196/64445
  53. Healthcare (Basel). 2025 Feb 01. pii: 298. [Epub ahead of print]13(3):
    Long COVID Research, 2020-2024: A PubMed-Based Bibliometric Analysis.
    Cristina Honorato-Cia, Elena Cacho-Asenjo, Antonio Martinez-Simon, Irene Aquerreta, Jorge M Núñez-Córdoba.
      Long COVID is a SARS-CoV-2 infection-associated chronic condition with great potential to impact health and socioeconomic outcomes. The research efforts to face the challenges related to long COVID have resulted in a substantial amount of publications, which warrants the need for bibliometric profiling. This is a large-scale PubMed-based bibliometric analysis of more than 390,000 COVID-19 publications. The overall aim was to update the profile of long COVID publications in comparison with the rest of the COVID-19 scientific literature through December 2024. The estimated proportion of long COVID publications was relatively low (2.3% of all COVID-19 publications), although the cumulative frequency (n = 8928) continues to pose a challenge for proper information management. Currently, "treatment" and "mechanism" appear to be the most predominant research topics in the long COVID literature. Interestingly, this evaluation revealed a distinctive profile of the long COVID literature, with a clear preponderance of "case report" and "mechanism" research topics when compared with other COVID-19 publications. This evaluation also identified and ranked the most prolific scientific journals in the production of long COVID-related publications. This study may improve the visibility of long COVID research and contribute to the management of the growing scientific knowledge on long COVID.
    Keywords:  COVID-19; SARS-CoV-2; bibliometrics; chronic COVID-19; long COVID; post COVID-19; post-acute sequelae; research profile
    DOI:  https://doi.org/10.3390/healthcare13030298
  54. Sensors (Basel). 2025 Jan 22. pii: 632. [Epub ahead of print]25(3):
    Exploring Trends and Clusters in Human Posture Recognition Research: An Analysis Using CiteSpace.
    Lichuan Yan, You Du.
      This study delves into interdisciplinary research directions in human posture recognition, covering vision-based and non-vision-based methods. Visually analyzing 3066 core research papers published from 2011 to 2024 with CiteSpace software reveals knowledge structures, research topics, key documents, trends, and institutional contributions. In-depth citation analysis identified 1200 articles and five significant research clusters. Findings show that in recent years, deep learning and sensor-based methods have dominated, significantly improving recognition accuracy, like the deep learning-based posture recognition method achieving 99.7% verification set accuracy with a 20-ms delay in a controlled environment. Logarithmic growth analysis of annual publications, supported by logistic model fitting, indicates the field's maturation since 2011, with a shift from early simple applications of traditional and deep learning algorithms to integrating interdisciplinary approaches for problem-solving as the field matures and a predicted decline in future breakthroughs. By integrating indicators like citation bursts, degree centrality, and sigma, the research identifies interdisciplinary trends and key innovation directions, showing a transition from traditional to deep learning and multi-sensor data fusion methods. The integration of biomechanics principles with engineering technologies highlights new research paths. Overall, this study offers a systematic overview to identify gaps, trends, and innovation directions, facilitating future research and providing a roadmap for innovation in human posture recognition.
    Keywords:  CiteSpace; human activity recognition (HAR); human posture recognition; inertial measurement unit (IMU); knowledge graph; visual analysis
    DOI:  https://doi.org/10.3390/s25030632
  55. Transl Pediatr. 2025 Jan 24. 14(1): 139-152
    Global trends and challenges in childhood caries: a 20-year bibliometric review.
    Liyun Zhai, Jiaxin Kong, Chaonan Zhao, Yang Xu, Xiaoxue Sang, Weiguang Zhu, Ning Yao.
      Childhood caries is a prevalent condition affecting nearly 50% of children globally across various age groups under 12 years, posing serious implications for their health and development. Understanding global research trends is essential for identifying knowledge gaps and guiding future studies aimed at developing effective intervention strategies. This study provides a comprehensive bibliometric review of childhood caries research from 2003 to 2023. Using CiteSpace, we analyzed 2,178 publications from the Web of Science (WOS) to map research trends, identify key challenges, and examine collaborative networks. The analysis revealed a threefold increase in research output, with the United States and Brazil leading contributions. Key challenges include persistent socioeconomic disparities influencing caries prevalence, limited access to effective treatments like silver diamine fluoride, and the complex role of the oral microbiome. International collaborations across 108 countries indicate a growing global effort to address these issues. Despite advancements, significant disparities in disease burden persist, especially in low- and middle-income countries, highlighting the urgent need to translate research into practice and develop targeted interventions. This review highlights the steady increase in research output on childhood caries over the past two decades, with the United States and Brazil leading contributions. Persistent disparities in disease burden and limited access to effective treatments remain critical challenges, particularly in low- and middle-income countries. These findings underscore the need for targeted research and policy efforts to address these inequities.
    Keywords:  Childhood caries; bibliometric analysis; global trends; intervention strategies
    DOI:  https://doi.org/10.21037/tp-24-415
  56. Materials (Basel). 2025 Jan 29. pii: 607. [Epub ahead of print]18(3):
    A Bibliometric and Systematic Review of the Use of Recycled Composite Materials with an Emphasis on the Mechanical Performance of Structures.
    Cristina Veres, Maria Tănase.
      The paper provides a bibliometric and systematic review of the utilization of recycled composite materials, focusing on their mechanical performance in structural applications. Analyzing 1525 publications from the Web of Science database using VOSviewer, the study identifies trends, key topics, and collaboration networks. Findings show that recycled fiber-reinforced polymers (FRPs) maintain up to 93% of their virgin tensile strength under optimal pyrolysis conditions, while mechanical recycling can reduce tensile properties by up to 29%. Advances in hybrid composites and recycling technologies have facilitated sustainable applications in the construction, transportation, and energy sectors. China is a dominant contributor to research on recycled composites, with the USA making strong contributions as well. Other countries, including England, India, and Germany, have active research communities, while nations such as Saudi Arabia, the Republic of Korea, and Spain demonstrate growing global participation in this field. The bibliometric analysis highlights a significant increase in global research activity, with key trends focusing on additive manufacturing, circular economy practices, and sustainability. Despite these advancements, challenges persist, including high operational costs and variability in recycled material quality. This review underscores the need for standardized protocols and improved lifecycle assessments to accelerate the adoption of recycled composites in engineering practices.
    Keywords:  VOSviewer; advanced recycling technologies; bibliometric analysis; composite materials; fiber-reinforced polymers; hybrid composites; mechanical properties; recycled
    DOI:  https://doi.org/10.3390/ma18030607
  57. JAMA Netw Open. 2025 Feb 03. 8(2): e2459371
    Research Domain Criteria in NIMH Grants Characterized Using Large Language Models.
    Roy H Perlis.
       Importance: Over the past decade, the leadership of the National Institute of Mental Health (NIMH) has emphasized the importance of a transdiagnostic approach to psychiatric investigation using Research Domain Criteria (RDoC) mapping more closely to neurobiology.
    Objective: To investigate whether research support from the NIMH for individual RDoC domains and for transdiagnostic investigation has changed over time and has had differential impact in terms of publication, citations, or patent filings.
    Design, Setting, and Participants: In this longitudinal cohort study, all R01, R21, and R03 studies funded by the NIMH between January 2003 and December 2023 were identified via the National Institutes of Health RePORTER database. Their abstracts were characterized in terms of RDoC domains (negative valence, positive valence, cognition, social, arousal, and sensorimotor) using a large language model.
    Main Outcomes and Measures: Primary outcomes were publications, citation impact estimated at 5 years from the index year of funding, and patents, examined using regression models adjusted for other grant characteristics.
    Results: Among 8897 R01, R03, and R21 projects, reflecting $17.7 billion of investment, abstracts of 3141 (35.3%) reflected negative valence; 1344 (15.1%), positive valence; 2781 (31.3%), cognition; 1607 (18.1%), social; 343 (3.9%), arousal; and 571 (6.4%), sensorimotor domains. A total of 1793 (20.2%) incorporated a transdiagnostic perspective. Positive and social domains were associated with fewer publications (difference, -1.13 [95% CI, -2.11 to -0.15] and -2.23 [95% CI, -3.15 to -1.30], respectively) and lesser citation impact (difference, -0.47 [95% CI, -0.75 to -0.18] and -1.19 [95% CI, -1.46 to -0.91], respectively) at 5 years. Social (adjusted odds ratio [AOR], 0.11; 95% CI, 0.04-0.23) and cognitive (AOR, 0.66; 95% CI, 0.48-0.89) domains and transdiagnostic proposals (AOR, 0.37; 95% CI, 0.21-0.60) were associated with lower likelihood of patent filing.
    Conclusions and Relevance: In this study of NIMH funding, grants reflecting different RDoC domains differed substantially in their scientific impact in terms of publications, citations, and patent generation. The findings suggest that large language models represent a promising approach to characterizing research proposals at scale, which may be useful in guiding resource allocation to maximize scientific return on investment.
    DOI:  https://doi.org/10.1001/jamanetworkopen.2024.59371
  58. J Food Sci. 2025 Feb;90(2): e70053
    Research trends 2024-2025.
      
    DOI:  https://doi.org/10.1111/1750-3841.70053
  59. Front Plant Sci. 2024 ;15 1542793
    Comprehensive review of mapping climate change impacts on tea cultivation: bibliometric and content analysis of trends, influences, adaptation strategies, and future directions.
    Altyeb Ali Abaker Omer, Chun-Hua Zhang, Jie Liu, Zhi-Guo Shan.
      Climate change has a profound impact on tea cultivation, posing significant challenges to yield, quality, and sustainability due to stressors such as drought, temperature fluctuations, and elevated CO₂ levels. This study aims to address these challenges by identifying and synthesizing key themes, influential contributions, and effective adaptation strategies for mitigating the impacts of climate change on tea production. A systematic bibliometric and content analysis was conducted on 328 peer-reviewed documents (2004-2023), following the PRISMA methodology. Performance analysis using Bibliometrix examined trends in publication output, leading contributors, and geographical distribution, while science mapping with VOSviewer revealed collaboration networks and thematic clusters. A detailed review of highly cited studies highlighted the primary climate variables affecting tea cultivation and identified innovative adaptation strategies, as well as critical knowledge gaps. The results show significant progress in understanding the physiological, biochemical, and molecular responses of tea plants to climate-induced stressors, including antioxidant mechanisms, secondary metabolite regulation, and genomic adaptations. Despite these advancements, challenges remain, particularly regarding the combined effects of multiple stressors, long-term adaptation strategies, and the socioeconomic implications of climate change. The findings underscore the need for interdisciplinary approaches that integrate molecular, ecological, and socioeconomic research to address these issues. This study provides a solid foundation for guiding future research, fostering innovative adaptation strategies, and informing policy interventions to ensure sustainable tea production in a changing climate.
    Keywords:  adaptation strategies; antioxidants; climate change; secondary metabolites; socioeconomic impacts; sustainability; tea cultivation; tea quality
    DOI:  https://doi.org/10.3389/fpls.2024.1542793
  60. PLoS One. 2025 ;20(2): e0317673
    Human capital, gender, institutional environment and research funding: Determinants of research productivity in German psychology.
    Martin Schröder, Isabel M Habicht, Mark Lutter.
      Which academics are more productive? The "sacred spark" theory predicts that some researchers are innately more productive than others, while the theory of cumulative advantage argues that small initial inequalities accumulate to large differences in productivity over time. Using a virtually complete panel dataset of all academic psychologists found in German universities in 2019, including their career information and publications, we examine under what conditions male and female psychologists publish more peer-reviewed articles. The strongest predictor of this is prior experience in publishing peer reviewed journal articles, irrespective of other prior endowments. This relationship between earlier and later productivity is not strongly confounded by career stage, affiliation with elite institutions, receipt of third-party funding, or parenthood. The effect of prior publications on current productivity explains why female academic psychologists publish less than men do. While female psychologists publish 34% less than their male counterparts, this gap diminishes to 17% after controlling for prior publication experience. This lends supports to the theory of cumulative advantage, which explains overall differences in productivity over entire careers by the accumulation of minor initial inequalities to large outcome differences over time.
    DOI:  https://doi.org/10.1371/journal.pone.0317673
  61. J Control Release. 2025 Feb 06. pii: S0168-3659(25)00055-0. [Epub ahead of print]
    Research trends in the use of nanobodies for cancer therapy.
    Jun Hou, Kejiang Du, Jinling Li, Zhenghui Li, Shaorui Cao, Shilin Zhang, Wenxing Huang, Heng Liu, Xiaomei Yang, Shuyang Sun, Shanzhao Mo, Tianyu Qin, Xilei Zhang, Shihua Yin, Xinyu Nie, Xiaoling Lu.
      Although there are many challenges in using nanobodies for treating various complex tumor diseases, including rapid renal clearance and the complex blood-brain barrier environment, nanobodies have shown great potential due to their high antigen affinity, excellent tumor penetration ability, and favorable safety profile. Since the discovery of the variable domain (VHH) of camelid heavy-chain antibodies in 1993, nanobodies have been progressively applied to various cancer therapy platforms, such as antagonistic drugs and targeting agents for effector domains. In recent years, several nanobody-based drugs, including Caplacizumab, KN-035, and Ozoralizumab, have been approved for clinical use. Among them, KN-035 is used for treating advanced solid tumors, and these advancements have propelled nanobody development to new heights. Currently, nanobodies are being rapidly applied to the treatment of a wide range of diseases, from viral infections to cancer, demonstrating strong advantages in areas such as targeted protein degradation, bioimaging, nanobody-drug conjugation, bispecific T-cell engagers, and vaccine applications. Bibliometric tools, including CiteSpace, HisCite Pro, and Alluvial Generator, were employed to trace the historical development of nanobodies in cancer research. The contributions of authors, countries, and institutions in this field were analyzed, and research hotspots and emerging trends were identified through keyword analysis and influential articles. Future trends were also predicted. This study provides a unique, comprehensive, and objective perspective on the use of nanobodies in tumor research, laying a foundation for future research directions and offering valuable insights for researchers in the field.
    Keywords:  Bibliometric; Cancer therapy; Nanobody; Nanobody-based immunotherapy; Visual analysis
    DOI:  https://doi.org/10.1016/j.jconrel.2025.01.045
  62. Front Nutr. 2025 ;12 1497207
    Global hotspots and trends of nutritional supplements for sick populations from 2000 to 2024.
    Chaofan Shi, Haitao Liu, Te Fu, Yuanquan Li, Haichang Zhao, Feiyue Liu.
       Background: Nutritional supplements (NS) can help patients by providing various nutrients such as essential vitamins and minerals, helping to prevent and recover from diseases. This study provides a broad overview of the field of NS for sick people through bibliometrics and visualization analysis, to analyze the status and development dynamics, explore the popular research questions and directions, and reveal the development trends and research frontiers.
    Methods: We searched the Web of Science Core Collection databases for literature related to NS for diseased populations from 2000 to 2024. A total of 1,550 articles were included in the analysis after screening. Analyses performed using CiteSpace and VOSviewer software.
    Results: The field of NS for the sick population has witnessed an overall rapid growth in the number of publications, which is divided into three phases: 2000-2008 was the exploratory phase, 2009-2017 was the sustained development phase, and 2018 to date is in the rapid development phase. Research focuses on dietary supplementation, oxidative stress, in vitro injections, development, antioxidant activity, double-blind trials, lipid supplements, functional foods, the health of diseased populations, and the risks of NS.
    Conclusion: Different supplements each possess unique benefits and should be chosen according to the type of disease to ensure they contain the corresponding nutrients. Vitamin supplements are widely mentioned among patient populations across the globe. Future trends may focus on applying nutritional supplements in gut microbiota and bioactive compounds. Researchers frequently mention the application of NS in women, infants, and children. It should continue to be monitored and optimized in the future to enhance its therapeutic effects, thereby accelerating patients' recovery and improving their quality of life.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; malnutrition; nutritional supplements; sick people
    DOI:  https://doi.org/10.3389/fnut.2025.1497207
  63. Molecules. 2025 Jan 26. pii: 563. [Epub ahead of print]30(3):
    CO2 Capture: A Comprehensive Review and Bibliometric Analysis of Scalable Materials and Sustainable Solutions.
    Domingo Cesar Carrascal-Hernández, Carlos David Grande-Tovar, Maximiliano Mendez-Lopez, Daniel Insuasty, Samira García-Freites, Marco Sanjuan, Edgar Márquez.
      The greenhouse effect and global warming, driven by the accumulation of pollutants, such as sulfur oxides (SOx), nitrogen oxides (NOx), and CO2, are primarily caused by the combustion of fossil fuels and volcanic eruptions. These phenomena represent an international crisis that negatively impacts human health and the environment. Several studies have reported novel carbon capture, utilization, and storage (CCUS) technologies, promising solutions. Notable methods include chemical absorption using solvents, and the development of functionalized porous materials, such as MCM-41, impregnated with amines like polyethyleneimine. These technologies have demonstrated high capture capacity and thermal stability; however, they face challenges related to recyclability and high operating costs. In parallel, biodegradable polymers and hydrogels present sustainable alternatives with a lower environmental impact, although their industrial scalability remains limited. This review comprehensively analyzes CO2 capture methods, focusing on silica-based porous supports, polymers, hydrogels, and emerging techniques, like CCUS and MOFs, while including traditional methods and a bibliometric analysis to update the field's scientific dynamics. With increasing investigations focused on developing new CCUS technologies, this study highlights a growing interest in eco-friendly alternatives. A bibliometric analysis of 903 articles published between 2010 and 2024 provides an overview of current research on environmentally friendly carbon capture technologies. Countries such as the United States, the United Kingdom, and India are leading research efforts in this field, emphasizing the importance of scientific collaboration. Despite these advancements, implementing these technologies in industrial sectors with high greenhouse gas emissions remains scarce. This underscores the need for public policies and financing to promote their development and application in these sectors. Future research should prioritize materials with high capture capacity, efficient transformation, and valorization of CO2 while promoting circular economy approaches and decarbonizing challenging sectors, such as energy and transportation. Integrating environmentally friendly materials, energy optimization, and sustainable strategies is essential to position these technologies as key tools in the fight against climate change.
    Keywords:  CO2; absorption; adsorption; carbon capture; climate change; utilization and storage
    DOI:  https://doi.org/10.3390/molecules30030563
  64. Ned Tijdschr Geneeskd. 2025 Feb 11. pii: D8413. [Epub ahead of print]169
    [Gender differences in career paths in medical academia: a nationwide study in the Netherlands].
    Silvan Licher, Daphne L van Helden, Margot M Weggemans, Coen B J van Deursen, Bas Holverda, Michiel van der Vaart, Miranda Wijdenes, Meike W Vernooij, Frank J Wolters.
       OBJECTIVE: To determine gender differences in career progression of physicians.
    DESIGN: Retrospective cohort study.
    METHOD: We examined career progression until 2023 of 715 physicians who received their PhD in the Netherlands in 2007/2008. We also pooled data from 7 national grant programs from 2005 up until Jan 1, 2023.
    RESULTS: Fifteen years after their PhD defence, 43% of physicians worked in academia, similar for men and women. Men published more than women (9[3-27] vs. 6[2-15] publications; p=0.001), especially in academia. Women were less likely than men to be appointed full professor (10/330 vs. 27/385; odds ratio[95% CI]: 0.41[0.20-0.87]), which was mediated for 55% by their number of scientific publications. Women increasingly applied for research grants over time, with an equal number of women and men receiving 'early career' grants since 2015. More men applied for 'established investigator' grants, without any gender differences in award rates.
    CONCLUSION: Career perspectives in the early phase after obtaining a PhD, including grant allocation, are similar for male and female physicians. Differences in their later career phase were partly related to a higher number of scientific publications by men, compared to women.
  65. PLoS One. 2025 ;20(2): e0316013
    Exploring the science and data foundation for Federal public lands decisions.
    Alison C Foster, Andrew T Canchola, Travis S Haby, Sarah K Carter.
      Public lands provide diverse resources, values, and services worldwide. Laws and policies typically require consideration of science in public lands decisions, and resource managers are committed to science-informed decision-making. However, it can be challenging for managers to use, and document the use of, science and data in their decisions. To better understand science and data use in Federal public lands decisions in the United States, we assessed the number, type, and age of documents cited in 70 Environmental Assessments (EAs) completed by the Bureau of Land Management (BLM) in Colorado from 2015-2019. We focused on the BLM, as they manage the largest area of public lands in the United States. We selected Colorado as our study area, as actions proposed on BLM lands in Colorado are representative of those across the nation. Fifty percent of citations were categorized as science and 23% as data. EAs contained an average of 17 citations (range 0-111), with documents analyzing effects of oil and gas development and recreation actions including the highest and lowest mean number of citations (41 and 6, respectively). Of individual resource analysis sections within EAs, 24% contained ≥1 science citation and 21% contained ≥1 data citation. Journal articles were the most cited type of document (26% of citations) followed by non-BLM inventories (13%). Forty-seven percent of citations were relatively recent (2010 or later); the oldest citation was from 1927. Commonly analyzed resources with the highest mean number of citations were socioeconomics, mineral resources, and noise. Fourteen of 33 commonly analyzed resources included <1 citation on average. Actions and resources with no or few citations represent opportunities for strengthening the transparent use of science and data in public lands decision-making.
    DOI:  https://doi.org/10.1371/journal.pone.0316013
  66. Recenti Prog Med. 2025 Feb;116(2): 65-68
    [Beyond quantity: rethinking quality and integrity in scientific research.]
    Luca De Fiore.
      Scientific publications have been suffering from a credibility crisis for years. This is the consequence of an excess of quantity in the production of articles produced for the sole purpose of advancing one's career and acquiring new funding to produce new studies and, consequently, new publications. To the problems of quantity are added those of quality: useless research results in scientific literature of little value. The preventive filter - entrusted to the peer review system - continues to prove insufficient to prevent the publication of useless or, increasingly, fraudulent articles. The method of critical review process should be radically reconsidered, as should the tools for measuring the impact of scientific articles: impact factors and other citation indices have proved incapable of giving an insight into the quality of what is published. The increased attention being paid to the scientific publication crisis can be a useful deterrent to improve quality and limit fraudulent behaviour. New generations of clinicians and researchers must be educated to respect the rules, and stricter and more timely penalties are needed for those who do not meet the standards that the scientific community has established over the years. More generally, the assessment of the quality of scientific production, and not its quantity, should inspire the evaluation of professional profiles when allocating new funding and selecting candidates for academic positions. Finally, journalism schools and masters' degrees in science communication must train new professionals capable of carrying out investigative journalism, which must be intensified in order to bring to light opportunistic and fraudulent behaviour.
    DOI:  https://doi.org/10.1701/4450.44436
  67. BMC Vet Res. 2025 Feb 08. 21(1): 59
    The inaccurate citation of the "Universal Declaration of Animal Rights" (UDAR) in the scientific literature: a scoping review.
    Alexandre Azevedo, Martin Whiting, Manuel Magalhães-Sant'Ana.
       BACKGROUND: The Universal Declaration of Animal Rights (UDAR), adopted in 1977 by an international NGO inspired by the Universal Declaration of Human Rights and made public the following year, aimed to establish a universal code for human conduct toward animals. The declaration was revised twice, in 1989 and 2018, but it failed to be internationally recognised or adopted. While its global influence remained limited, misinterpretations of its scope and context have proliferated in legal and veterinary documents. To gauge its impact on scientific literature, a scoping review across three databases (Scopus, Web of Science Core Collection, and Google Scholar) was conducted for publications citing the UDAR from 1979 to 2022.
    RESULTS: In terms of research field, the UDAR is mostly cited in the fields of law (27%), philosophy, ethics, and religion (17%), clinical medicine (17%), and basic medicine (11%). The 1978 UDAR version was most often cited. Among 305 screened publications, 47.9% contained erroneous or misleading claims about the UDAR. Common errors included linking the UDAR to UNESCO (34.8%) and conferring it universal endorsement or legally binding value (10.2%). More than half (57%, 59/103) of the mentions in the ethics section contained errors, namely confusing UDAR with other animal protection texts. Regarding the type of animal use, most misleading claims were found in scientific publications focusing on the use of animals in research.
    CONCLUSIONS: The misappropriation of the UDAR risks providing a false sense of legitimacy and moral compass to editors, reviewers, and readers regarding animal use and highlights that the authors are unaware of ethical or regulatory frameworks governing the proper use of animals in science. This is particularly relevant because the 1978 version, which is antithetical to animal use in science, was most often cited, raising concerns about the governance of animal research in some institutions and the efficacy of the peer review process in detecting these errors. Finally, UDAR mentions grew more than the estimated growth of scientific publications worldwide, thus suggesting an increase in its influence.
    Keywords:  Animal rights; Animal welfare; Bioethics; Citation error; Research ethics
    DOI:  https://doi.org/10.1186/s12917-025-04470-z
  68. J Surg Res. 2025 Jan;pii: S0022-4804(24)00765-0. [Epub ahead of print]305 286-294
    A Cross-Sectional Public Data Study of Female Leaders in Surgical Critical Care Fellowships.
    Sin Lei Pui, Penelope N Halkiadakis, Andrew H Tran, Nuala Spillane, Allison Mo, Avanti Badrinathan, Prerna Ladha, Vanessa P Ho.
       INTRODUCTION: Female leadership in surgery has been associated with improved gender parity in staffing and stronger focus on wellness. The aim of this study was to examine the gender distribution of leaders in Surgical Critical Care (SCC) training programs. We hypothesize that male and female leaders would have different levels of scholarly achievements, and that programs led by women would be more likely to emphasize wellness initiatives in public-facing websites.
    METHODS: We analyzed SCC programs from 2018 to 2022, and identified leaders in the roles of Fellowship Program Director (PD), Division Chief, and Department Chair were from department websites. Program information, characteristics of leaders such as additional degrees and academic productivity, and wellness initiatives were collected. Academic productivity was approximated using the H-index.
    RESULTS: Data from 126 SCC program showed that women were underrepresented (female faculty = 33%, female leaders = 27%). Most female leaders were PDs (61.3%) rather than division chief or chair. Male and female leaders had similar H-index and additional degrees (all P > 0.05). Female leadership correlated with higher female faculty representation (P < 0.001). Programs with female PDs were more likely to emphasize wellness in public-facing platforms (odds ratio 3.34, P = 0.03).
    CONCLUSIONS: Female leadership in SCC is associated with greater female representation and a stronger emphasis on wellness initiatives. This study reinforces importance of inclusive leadership in Acute Care Surgery.
    Keywords:  Female leadership; H-index; Program director; Surgery; Surgical critical care; Wellness
    DOI:  https://doi.org/10.1016/j.jss.2024.11.023
  69. J Ayurveda Integr Med. 2025 Feb 08. pii: S0975-9476(24)00193-1. [Epub ahead of print]16(2): 101078
    Research status of traditional & complementary medicine systems across the world.
    Vedvati Bhapkar, Vallari Nisargand, Pawankumar Godatwar, Supriya Bhalerao.
       BACKGROUND: Despite strong presence of biomedicine, traditional and complementary medicine (T & CM) systems have sustained with their multidimensional connect with people. However, their scientific acceptance and mainstreaming falls short due to inadequacies in research. Also, available reports in this regard scarcely focus on their individuality and present them as a consolidated entity.
    OBJECTIVES: The present study was carried out to elucidate individual research status of certain WHO- acknowledged T & CM systems in a customized framework of indirect indicators.
    MATERIAL AND METHODS: The research status of selected systems was assessed on basis of quantitative indicators viz., research dissemination outcomes concerned with scientific documents and researchers, contribution in COVID-19 prevention and management, and patents profile.
    RESULTS: Systems such as Traditional Chinese Medicine and Acupuncture fare better than most others. The number of documents in multidisciplinary SCOPUS database was larger than those in PubMed, a healthcare database for almost all systems. Out of 28 lead authors, half belonged to developed countries, viz., USA and Germany. Highest citation count was recorded for TCM (n = 2238). Of the 105 journals analyzed, 40 were not dedicated to specific T & CM system. Most number of discretely dedicated journals (n = 20) mentioned TCM as primary scope. Cochrane systematic reviews (n = 142) and protocols (n = 33) were highest for Acupuncture, while many systems had zero presence. Maximum COVID-19 related clinical studies were registered for TCM (n = 335), followed by Ayurveda (n = 112). TCM related patents were also highest among all.
    CONCLUSION: There is a huge variation in the research status of different T & CM systems. The stakeholders of these systems need to establish a strong evidence base at par with biomedicine. United efforts at global level through organizations such as WHO-Global Traditional Medicine Centre (GTMC) might be helpful in this regard.
    Keywords:  Ayurveda; Conventional medicine; Research translation; TCM; Traditional medicine
    DOI:  https://doi.org/10.1016/j.jaim.2024.101078
  70. PLoS One. 2025 ;20(2): e0305666
    Publication bias in the social sciences since 1959: Application of a regression discontinuity framework.
    Julia Jerke, Antonia Velicu, Fabian Winter, Heiko Rauhut.
      While publication bias has been widely documented in the social sciences, it is unclear whether the problem aggravated over the last decades due to an increasing pressure to publish. We provide an in-depth analysis of publication bias over time by creating a unique data set, consisting of 12340 test statistics extracted from 571 papers published in 1959-2018 in the Quarterly Journal of Economics. We, further, develop a new methodology to test for discontinuities at the thresholds of significance. Our findings reveal, that, first, in contrast to our expectations, publication bias was already present many decades ago, but that, second, bias patterns notably changed over time. As such, we observe a transition from bias at the 10 percent to bias at the 5 percent significance level. We conclude that these changes are influenced by increasing computational possibilities as well as changes in the acceptance rates of scientific top journals.
    DOI:  https://doi.org/10.1371/journal.pone.0305666
  71. Environ Sci Pollut Res Int. 2025 Feb 13.
    Comments on "Research trends on the relationship between air pollution and cardiovascular diseases in 2013-2022 - A scientometric analysis".
    Daifallah M Alrazeeni, Fateha Tuj Johra, Fazila Akter, Muhammad Join Uddin, Silvia Ferdousi, Mst Rina Parvin, Moustaq Karim Khan Rony.
      
    DOI:  https://doi.org/10.1007/s11356-025-36084-1
  72. J Clin Epidemiol. 2025 Feb 11. pii: S0895-4356(25)00052-6. [Epub ahead of print] 111719
    Cochrane Reviews' authorship has become more gender-diverse but remains geographically concentrated: A meta-research study.
    Ahmad Sofi-Mahmudi, Jana Stojanova, Elpida Vounzoulaki, Eve Tomlinson, Ana Beatriz Pizarro, Sahar Khademioore, Etienne Ngeh, Amin Sharifan, Lucy Elauteri Mrema, Alexis Ceecee Britten-Jones, Santiago Castiello de Obeso, Vivian A Welch, Lawrence Mbuagbaw, Peter Tugwell.
       OBJECTIVE: The aim of this study was to examine the distribution of country, region, language, and gender diversity in the authorship of Cochrane reviews and compare it to non-Cochrane systematic reviews.
    STUDY DESIGN AND SETTING: We retrieved all published articles from the Cochrane Library (until November 6, 2023) using a web crawling technique that extracted pre-specified data fields, including publication date, review category, and author affiliations. For comparison, non-Cochrane systematic reviews were identified through PubMed using E-utility calls. We determined the country, region of affiliations and gender of the first, corresponding, and last authors for Cochrane reviews; the same fields were determined for first authors only for non-Cochrane reviews due to data availability. Trends in geographical and gender diversity over time were evaluated using logistic regression. Fisher's exact test was used for comparisons. Diversity trends between Cochrane and non-Cochrane reviews were explored through visual presentation, Pearson's product-moment correlation, and the Granger Causality Test.
    RESULTS: This comprehensive analysis included 22,681 Cochrane reviews and 224,484 non-Cochrane reviews. Cochrane reviews showed increasing diversity in several areas: representation of first authors from non-English speaking countries rose substantially (from 16.7% in 1996 to 42.8% in 2023), and female first authorship more than tripled (from 15.0% in 1996 to 55.6% in 2023). Representation from LMICs in Cochrane reviews has declined recently (from a peak of 23.2% in 2012 to 18.4% in 2023). Among Cochrane Review Groups, diversity varied notably, with Sexually Transmitted Infections achieving the highest representation from LMICs (68.1% of first authors). In 2023, non-Cochrane reviews showed higher representation from non-English speaking countries (56.9%) and LMICs (50.8%) compared to Cochrane reviews. The patterns of gender diversity between Cochrane and non-Cochrane reviews showed strong correlations for female first authorship (r=0.829, P<0.001), suggesting parallel evolution over time.
    CONCLUSION: Both Cochrane and non-Cochrane reviews demonstrate important progress in author diversity, particularly in gender representation and inclusion of authors from non-English speaking countries. While non-Cochrane reviews show stronger representation from LMICs, both review sources reflect the evolving landscape of global evidence synthesis.
    Keywords:  Authorship; Cochrane; Diversity; Equity; Inclusion; Publications; Review
    DOI:  https://doi.org/10.1016/j.jclinepi.2025.111719
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