bims-evares Biomed News
on Evaluation of research
Issue of 2025–02–02
105 papers selected by
Thomas Krichel, Open Library Society
  1. The Top 100 Cited Articles in Male Aesthetic Surgery: A Bibliometric Analysis.
  2. What Is the Current Status of Research on the Impact of Digitalization in Medicine? A Bibliometric Analysis.
  3. Research Tendency and Frontiers of Multifocal Lenses in Myopic Control in the Past Two Decades: A Bibliometric Analysis.
  4. Trends in Dehydration in Older People: Identifying Landmark Scientific Contributions.
  5. Bibliometric analysis of global research trends in vestibular neuritis (1980-2024).
  6. Bibliometric analysis in Scopus of scientific production on the relationship between periodontitis and gastrointestinal cancer (2014 - 2023).
  7. Global research trends of BRUE (brief resolved unexplained event) or formerly ALTE (apparent life-threatening event): A comprehensive visualization and bibliometric analysis from 1988 to 2024.
  8. Mapping Trends and Hotspots Regarding the Use of Lung Ultrasound in the Field of Anesthesiology: A Bibliometric Analysis of Global Research.
  9. Hotspots and global trends in research of host immune response in periodontitis: A bibliometric analysis.
  10. The literature on digital technologies for removable dental prostheses: A two-decade bibliometric analysis.
  11. Valvular heart disease and heart-related disease: a bibliometric and visual analysis from 2000 to 2023.
  12. Analysis of the Top Articles and Authors of the Journal of Orthopaedic Trauma and Bibliometric Comparison of Impact Factors of Orthopaedic Surgery Journals.
  13. Evolution of Artificial Intelligence in Medical Education From 2000 to 2024: Bibliometric Analysis.
  14. Global Research Hotspots and Trends in Advances of the Ilizarov Technique: A Bibliometric Mapping.
  15. Hotspots and trends in stem cell therapy for liver fibrosis and cirrhosis: A bibliometric analysis.
  16. A bibliometric analysis of the 50 most cited articles on acromioclavicular joint reconstruction.
  17. Bibliometric analysis of the scientific production of rheumatology departments in Spain during the 2013-2022 period.
  18. Minimally invasive pancreaticoduodenectomy: A bibliometric method applied to the top one hundred cited articles.
  19. A bibliometric study on the impact of gut microbiota on the efficacy of immune checkpoint inhibitors in cancer patients: analysis of the top 100 cited articles.
  20. Orofacial cleft research in Nigeria: a bibliometric analysis.
  21. Global research trends in music therapy for surgery: a bibliometric analysis (2009-2023).
  22. International youth football research developments: A CiteSpace-based bibliometric analysis.
  23. Global trends in surgically based treatment of anal fistula in Crohn's disease: a bibliometric and visualization analysis.
  24. Exploring the progress and trends of immunotherapy for type 1 diabetes: A comprehensive bibliometric analysis spanning nearly two decades.
  25. Top 100 most-cited articles on apoptosis of non-small cell lung cancer over the past two decades: a bibliometrics analysis.
  26. Research Hotspots of Interferon Gamma in the Treatment of Lung Cancer: A Bibliometric Analysis Based on CiteSpace.
  27. Research progresses and hotspots on glucose metabolic reprogramming in breast cancer: a bibliometric analysis over the past two decades.
  28. Bibliometric insights into astrocytic roles in depression and treatment.
  29. Bibliometric analysis of liposarcomas treatment from 2004 to 2023.
  30. Global research hotspots and trends in oxidative stress-related diabetic nephropathy: a bibliometric study.
  31. Opportunities and challenges of immuno-oncology: A bibliometric analysis from 2014 to 2023.
  32. A scientometric analysis of highly cited papers in Indian spine research (1995-2024): navigating the impact.
  33. The global research of magnetic resonance imaging in Alzheimer's disease: a bibliometric analysis from 2004 to 2023.
  34. Study based on bibliometric analysis: potential research trends in fluid management for sepsis.
  35. Bibliometric analysis of global research status and trends of circadian rhythms in cancer from 2004 to 2024.
  36. Ferroptosis in kidney disease: a bibliometric analysis from 2012 to 2024.
  37. Research hotspots and trends in gut microbiota and nonalcoholic fatty liver disease: A bibliometric study.
  38. Bibliometric Analysis of the Highest Cited Cosmetic Upper Facial Plastic Surgery Articles Over 50 Years.
  39. Top 75 most-cited articles in hand microsurgery: A bibliometric and visualised analysis.
  40. Bibliometric analysis of published works in ocular trauma: a growing focus on open globe injury.
  41. Biological function of d-tryptophan: a bibliometric analysis and review.
  42. Vegetable Fibers in Cement Composites: A Bibliometric Analysis, Current Status, and Future Outlooks.
  43. Exploring the landscape of exosomes in heart failure: a bibliometric analysis.
  44. Exploring the Research Landscape of Transcranial Direct Current Stimulation in Stroke: A Bibliometric Review.
  45. Global research hotspots and trends in DNA vaccine research: A bibliometric and visualization study from 2014 to 2024.
  46. Bibliometric analysis of photodynamic research in bladder cancer: trends and future directions.
  47. Seeing beyond words: nanotechnology in hepatocellular carcinoma - a bibliometric study.
  48. The top 100 cited papers on mental health and virtual reality: a bibliometric analysis.
  49. A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases.
  50. A bibliometric and visualized analysis of heartland virus.
  51. Letter to the Editor regarding "Global research trends and hotspots in gestational diabetes and long-term cardiovascular health: A bibliometric analysis."
  52. Community Integration of Disability: A Bibliometric and Knowledge-Map Analysis.
  53. Registered reports in psychology across scholarly citations and public dissemination: A comparative metaevaluation of more than a decade of practice.
  54. The 100 most-cited articles in WALANT hand surgery: A bibliometric and visualized analysis.
  55. Evolution of artificial intelligence in healthcare: a 30-year bibliometric study.
  56. Scientific mapping of the nexus between entrepreneurial orientation and environmental sustainability: bibliometric analysis.
  57. A Review on Blockchain Applications in Operational Technology for Food and Agriculture Critical Infrastructure.
  58. A retrospective analysis of medical student authorship in highest impact radiology journal publications.
  59. Trends in shoulder arthroplasty research over the decades.
  60. An Investigation of Gender Representation and Collaboration in Academic Plastic Surgery Research.
  61. An overview of radiography research and publication productivity in Denmark.
  62. Publication rates and features of abstracts presented at emergency medicine congresses in Türkiye: An analysis of 10,055 abstracts.
  63. Lack of transparency for Investigators in clinical trials: A bibliometric analysis of literature.
  64. Advances in gastrointestinal vascular bleeding disorders: Successful sirolimus treatment in colonic angioectasia.
  65. Oncolytic Virotherapy in Otorhinolaryngologic Neoplasms: A Scoping Review and Bibliometric Analysis.
  66. Gender influence on career trajectory as a shoulder and elbow surgeon.
  67. A trend of osteocalcin in diabetes mellitus research: bibliometric and visualization analysis.
  68. Research Trends of Traditional Chinese Medicine Therapies on Chronic Obstructive Pulmonary Disease: A Bibliometric Analysis.
  69. Bibliometric Analysis of Global Pediatric Research on Cow's Milk Protein Allergy.
  70. Linking citation and retraction data reveals the demographics of scientific retractions among highly cited authors.
  71. Global hotspots and trends on environmental exposure and cardiovascular disease from 1999 to 2022.
  72. Global Landscape of Knowledge Mapping and Research Trends in Hyaluronic Acid for Wound Healing: A Bibliometric and Visualization Analysis (1952-2023).
  73. Unveiling hotspots of emerging research in the miRNA-related mechanism underlying cancer through comprehensive bibliometric analysis with implications for precision medicine and non-invasive diagnostics.
  74. A scientometric study on research trends and characteristics of oral leukoplakia and oral lichen planus.
  75. The enigma of journal impact factors: determinants of impact factors for journals in General and Internal Medicine, Surgery, and Anaesthesiology.
  76. Current views and trends of nanomaterials as vectors for gene delivery since the 21st century: a bibliometric analysis.
  77. A Scientometric Exploration of the Socket-shield Technique in Oral Implantology: Trends and Spatiotemporal Dynamics.
  78. Vexatious and euphemistic affairs in retractions of scientific publications: A pilot study.
  79. Four Decades of Bacillus Biofertilizers: Advances and Future Prospects in Agriculture.
  80. Health insurance expansion and academic production: The case of Medicare Part D legislation.
  81. Revolutionizing medical education: Surgery takes the lead in virtual reality research.
  82. Sex and authorship in global cancer research.
  83. Patterns of diversity in biomedical coauthorships: An analysis across authors' ethnicity, gender, age, and expertise.
  84. A scientometric study on research trends and characteristics of discoid lupus erythematosus.
  85. A scientometric study of syphilis research by dermatologists and stomatologists: Underpinning their roles in public health.
  86. Landscape of Global Pediatric Oncology Publications: A Cross-Sectional Analysis.
  87. Vascularised Composite Allotransplantation - A guide to optimal dissemination of scientific outputs.
  88. Mechanistic and bibliometric insights into RpoS-mediated biofilm regulation and its strategic role in food safety applications.
  89. A comprehensive bibliographic study on mental illness.
  90. A Comprehensive Review of Psychosocial, Academic, and Psychological Issues Faced by University Students in India.
  91. Why does cardiology have many extreme publishing authors?
  92. Global advances and innovations in bacteria-based biosorption for heavy metal remediation: a bibliometric and analytical perspective.
  93. Reevaluating Gender Disparities in Academic Productivity in Plastic Surgery: Women Produce Impactful Research, Yet Their Output Falls Short.
  94. Beyond disability: A scientometric review of quality of life in developmental disabilities.
  95. The misalignment of incentives in academic publishing and implications for journal reform.
  96. Chitosan research progress for smart packaging applications: a literature review.
  97. [Health science students as RENACYT researchers at a peruvian university: A bibliometric study].
  98. SEMI-AUTOMATED EXTRACTION OF RESEARCH TOPICS AND TRENDS FROM NCI FUNDING IN RADIOLOGICAL SCIENCES FROM 2000-2020.
  99. Emerging trends and innovations in polysaccharide-derived EMI shielding materials: A comprehensive review of bibliometric and performance analysis.
  100. International Medical Graduates in Academic Cardiothoracic Surgery.
  101. A Multidisciplinary Multimodal Aligned Dataset for Academic Data Processing.
  102. Responding to: Rethinking Leadership in Academic Medicine: Embracing a Broader Definition of Success : Original article: Sticky Floor, Broken Ladder, and Glass Ceiling in Internal Medicine Academic Ranking, Leadership, and Research Productivity.
  103. Gender Representation Among Speakers and Chairs at the European Society for Vascular Surgery Annual Meetings.
  104. A bibliometric review on ghost fishing: Impacts on marine environment and governing measures.
  105. Bridging academia and public interest: the impact of Altmetrics on osteoporosis treatment research.
  1. Aesthetic Plast Surg. 2025 Jan 24.
    The Top 100 Cited Articles in Male Aesthetic Surgery: A Bibliometric Analysis.
    Andrew Hannoudi, Kinan Sawar, David J Pegouske, Guillermina Nava.
       BACKGROUND: In recent years, male aesthetic surgery has significantly risen in popularity, attributable to surgical technique advancements and societal changes. Research in this subject area has increased accordingly, underscoring the need to identify the most influential articles. This study evaluates the bibliometric characteristics of the top 100 most cited male aesthetic surgery articles published in the last 50 years.
    METHODS: The 100 most cited articles in male aesthetic surgery from 1974 to 2024 were identified using Web of Science. We examined key trends in authorship contribution, institutional affiliation, country affiliation, citation count, journal impact factor, eigenfactor score, article influence score, and funding agency contribution.
    RESULTS: As of June 2024, the top 100 articles were cited a total of 7,341 times, with individual citation counts ranging from 18 to 243. The top cited article was "A Review of Psychosocial Outcomes for Patients Seeking Cosmetic Surgery," published in 2004. Of the 100 articles, the top contributing authors were Dr. Joel E. Pessa (5%) and Dr. Rod J. Rohrich (4%). The top contributing organization was the University of Texas System (8%). The peak year for publications was 2008, accounting for 10% of articles. The USA contributed to 60 of 100 articles. Plastic and Reconstructive Surgery was the most prolific journal, publishing 33% of articles.
    CONCLUSION: Through a historical analysis of the field's development up to its present state, our findings serve as a valuable resource for those interested in advancing their understanding of male aesthetic surgery literature.
    LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors  www.springer.com/00266 .
    Keywords:  Aesthetic surgery; Bibliometric analysis; Cosmetic surgery; Male aesthetic surgery; Research trends
    DOI:  https://doi.org/10.1007/s00266-025-04693-3
  2. Healthcare (Basel). 2025 Jan 07. pii: 93. [Epub ahead of print]13(2):
    What Is the Current Status of Research on the Impact of Digitalization in Medicine? A Bibliometric Analysis.
    Gabriela Badareu, Silviu Cârstina, Felicia Militaru, Marian Ilie Siminică, Daniel Cîrciumaru.
      Objectives: This study conducts a bibliometric analysis to map key trends in the digitalization of medicine, a rapidly evolving field that incorporates advancements such as artificial intelligence, telemedicine, and Big Data. The analysis aims to identify the most prolific authors, highly cited works, leading countries, and contributions from research institutions, while also exploring emerging trends through keyword analysis. Methods: A dataset comprising 2606 scientific papers was retrieved from the Web of Science database. The analysis was performed using bibliometric techniques and VOSviewer software to evaluate citation patterns, author productivity, country activity, and institutional contributions. Results: The findings reveal a substantial increase in research activity on the digitalization of medicine, with notable contributions from Germany, the USA, and China. These countries host leading academic institutions actively driving the field. Keyword analysis highlights emerging trends in artificial intelligence, telemedicine, and Big Data. Extensive international collaborations further underscore the global nature of this research domain. This study provides a comprehensive overview of the evolution and current trends in the digitalization of medicine. Conclusions: It highlights the significant role of international collaboration and identifies key areas of development, offering valuable insights for future research directions in this dynamic sector.
    Keywords:  VOSviewer; bibliometric analysis; digitalization; medical research; medicine; trends
    DOI:  https://doi.org/10.3390/healthcare13020093
  3. Healthcare (Basel). 2025 Jan 20. pii: 204. [Epub ahead of print]13(2):
    Research Tendency and Frontiers of Multifocal Lenses in Myopic Control in the Past Two Decades: A Bibliometric Analysis.
    Lingli Jiang, Manrong Yu, Jiangxiong Cai, Yingying Wang, Hao Hu, Minjie Chen.
      Background: This study aimed to analyze the research progress on the use of a multifocal lens for myopic control throughout the 21st century, utilizing bibliometric analysis. Methods: Publications related to multifocal lenses from 2001 to 2024 were searched on the Web of Science core collection (WoSCC) database. VOSviewer (Version 1.6.19) and Bibliometrix package (Version 4.3.0) were used to perform the bibliometric analysis. Primary information including the publication number per year, country or region, journal, keyword, and title of the literature was extracted and analyzed. Results: A total of 234 articles from 31 countries were retrieved. The number of publications related to multifocal lenses had a rapid growth phase from 2016 to 2024. The United States, Australia, China, and Spain emerged as leading contributors to the research landscape. Ophthalmic and Physiological Optics was the most popular journal in this field, and the most frequently cited article was published in Optometry and Vision Science. Myopic progression was the main topic in this research field as well as the principal keywords of emerging research hotspots. Conclusions: Our bibliometric study provides a pioneering overview of the research trends and evolution in the application of a multifocal lens for myopic control. These findings provide a deep insight into current research frontiers and hot directions, offering a valuable reference for further research.
    Keywords:  CiteSpace; VOSviewer; bibliometric; children; contact lens; multifocal lenses; myopic control
    DOI:  https://doi.org/10.3390/healthcare13020204
  4. Nutrients. 2025 Jan 07. pii: 204. [Epub ahead of print]17(2):
    Trends in Dehydration in Older People: Identifying Landmark Scientific Contributions.
    Olga Masot, Alexandra Pascual, Judith García-Expósito, Jéssica Miranda, Carla Camí, Teresa Botigué.
       BACKGROUND: Dehydration and low fluid intake cause the most prevalent electrolyte imbalance in older adults and increase their morbi-mortality.
    OBJECTIVE: To analyse the scientific production on dehydration in older adults.
    METHODS: A bibliometric analysis was performed using the Web of Science Core Collection database. The data were analysed using two software programs, the Bibliometric package for RStudio version 4.2.2, and VOSviewer 1.6.18 for the analysis of the scientific production, authors, citations, countries and collaborations, journals, research areas, and keywords.
    RESULTS: A total of 205 articles were selected. An increase in the number of publications has been observed since 2012, with 2021 being the most productive year. With respect to scientific production, although the USA had the most publications, the two most prolific authors were affiliated with an institution located in the UK, with this country having the most collaborations with other countries in the development of the subject matter. The co-occurrence analysis indicated that the words with the highest occurrence were dehydration (n = 103), hydration (n = 39), prevalence (n = 30), mortality (n = 29), and thirst (n = 29).
    CONCLUSIONS: This is the first bibliometric analysis that shows the publication trends on dehydration in older adults. Although the number of publications is limited, they have increased in number in the last few years. The research trends are centred on the prevalence of dehydration and its related factors. More studies are needed that are centred on interventions to correct the problem, to help fight against the electrolyte imbalances that occur, and to reduce the morbi-mortality associated with this condition.
    Keywords:  bibliometrics; dehydration; fluid intake; older people
    DOI:  https://doi.org/10.3390/nu17020204
  5. Eur Arch Otorhinolaryngol. 2025 Jan 25.
    Bibliometric analysis of global research trends in vestibular neuritis (1980-2024).
    Mehmet Akif Dündar, Ahmet Avcı, Müşerref Arık, Ahmet Tayfur Akcan, Hasan Kazak.
       PURPOSE: Vestibular neuritis (VN) is a common cause of vertigo with significant impact on patients' quality of life. This study aimed to analyze global research trends in VN using bibliometric methods to identify key themes, influential authors, institutions, and countries contributing to the field.
    METHODS: We conducted a comprehensive search of the Web of Science Core Collection database for publications related to VN from 1980 to 2024. Bibliometric data including publication year, keywords, citations, authors, journals, institutions, and countries were extracted and analyzed using VOSviewer software.
    RESULTS: A total of 624 publications were identified, showing a steady increase in VN research output, particularly after 2003. South Korea and the USA were the most prolific countries, while Acta Oto-Laryngologica and Otology & Neurotology were the leading journals in terms of publication count. Michael Strupp emerged as the most productive author. Keyword analysis revealed prominent research themes including diagnosis, treatment (vestibular rehabilitation, pharmacological interventions), pathophysiology, and the impact of VN on vestibular function.
    CONCLUSIONS: This bibliometric analysis provides a comprehensive overview of global VN research. The findings highlight the growing research interest in VN, with a focus on improving diagnostic accuracy, optimizing treatment strategies, and understanding the underlying mechanisms. This study can serve as a valuable resource for researchers, clinicians, and policymakers interested in the field of VN.
    Keywords:  Bibliometric analysis; Research trend; Vertigo; Vestibular neuritis; Vestibular rehabilitation
    DOI:  https://doi.org/10.1007/s00405-024-09159-x
  6. Med Oral Patol Oral Cir Bucal. 2025 Jan 26. pii: 26969. [Epub ahead of print]
    Bibliometric analysis in Scopus of scientific production on the relationship between periodontitis and gastrointestinal cancer (2014 - 2023).
    A-S Asmat-Abanto, A Portocarrero-Reyes, R-E Espejo-Carrera, C-A Minchón-Medina, D-J Timaná-Palacios.
       BACKGROUND: Recent studies have suggested that some opportunistic periodontal pathobionts have oncogenic properties. However, few bibliometric studies investigate the relationship between periodontitis and gastrointestinal cancer. This bibliometric study aimed to analyze these epidemiological studies conducted between 2014 and 2023 to guide future research.
    MATERIAL AND METHODS: In March 2024, the Scopus database was explored. The articles selected were subjected to a bibliometric analysis of study designs, trends in annual scientific production, and networks of collaboration among countries. Furthermore, the most outstanding countries, academic institutions, authors and journals with the most significant number of publications and the top most cited articles were analyzed. For this purpose, Microsoft Excel, SPSS and VOSviewer 1.6.20 were used.
    RESULTS: A total of 123 documents were included for analysis. China contributed the most significant number of publications (33 articles) and the United States had the most significant number of citations (2709). Weimin Ye (h-index:81) and Dominique Michaud (h-index:73) were the most prolific authors (5 articles); Dominique Michaud also had the most citations (470). International Journal of Cancer was the journal with the highest number of articles published (6), in addition to being the publication that had the most citations of these articles (409). Tufts University in the United States had the highest number of citations.
    CONCLUSIONS: Between 2014 and 2023, 123 articles on the relationship between periodontitis and gastrointestinal cancer were published. The largest scientific production was found in China, and the most cited articles were those from the United States. Likewise, the research design most commonly used was the cross-sectional type.
    DOI:  https://doi.org/10.4317/medoral.26969
  7. Am J Emerg Med. 2025 Jan 20. pii: S0735-6757(25)00054-3. [Epub ahead of print]90 129-141
    Global research trends of BRUE (brief resolved unexplained event) or formerly ALTE (apparent life-threatening event): A comprehensive visualization and bibliometric analysis from 1988 to 2024.
    Derşan Onur, Murat Çetin.
       OBJECTIVE: This study aimed to conduct a comprehensive bibliometric analysis of the literature on Brief Resolved Unexplained Event (BRUE) and its predecessor, Apparent Life-Threatening Event (ALTE), from 1988 to 2024, in order to identify research trends, collaborative networks, and areas of focus in this field.
    METHODS: We analyzed articles indexed in Scopus and Web of Science using various bibliometric indicators. The visualization of bibliometric networks was performed using VOSviewer and bibliometrix. Publication trends, citation analysis, co-authorship networks, and keyword co-occurrence were examined.
    RESULTS: A total of 270 articles were analyzed, of which 85.56 % were research articles and 14.44 % were review articles. The number of publications showed a significant increase over time (r = 0.73, p < 0.001). The United States emerged as the leading contributor with strong international collaborations. The most prolific journals were Pediatrics, Pediatric Emergency Care, and Journal of Pediatrics. Keyword analysis revealed a shift from terms associated with life-threatening events (e.g., SIDS, sleep apnea syndrome) to more specific terminology (BRUE) and methodological keywords over time. However, the 2016 redefinition of ALTE to BRUE did not result in a corresponding increase in publications.
    CONCLUSION: This bibliometric analysis provides valuable insights into the evolution and current state of BRUE/ALTE research. The findings highlight the field's progression toward more precise, evidence-based approaches. The identified research trends and gaps, particularly the limited studies from developing countries, offer direction for future research. These results can inform clinical practice, guide research priorities, and support the development of standardized guidelines for BRUE/ALTE management.
    Keywords:  ALTE; BRUE; Bibliometric analysis; Emergency; Pediatrics
    DOI:  https://doi.org/10.1016/j.ajem.2025.01.045
  8. Med Devices (Auckl). 2025 ;18 53-62
    Mapping Trends and Hotspots Regarding the Use of Lung Ultrasound in the Field of Anesthesiology: A Bibliometric Analysis of Global Research.
    Wencai Jiang, Kang Kang, Xinyu Zhou, Xuemeng Chen, Hai Yu, Xianjie Zhang.
       Purpose: Lung ultrasound (LUS) is increasingly utilized in the field of anesthesiology due to its focused, quick application and the advantage of not exposing patients to ionizing radiation. This study aims to analyze the status and trends in this area from a macroscopic perspective.
    Methods: A bibliometric analysis was conducted using the Web of Science (WoS) Core Collection. The analysis and visualization were performed using WoS, Excel, VOSviewer, and CiteSpace. Parameters such as publications, countries, institutions, journals, and keywords were analyzed.
    Results: A total of 133 articles published over the last 10 years were analyzed to clarify the current status and future trends on the use of LUS in anesthesiology. The number of publications increased markedly from May 1, 2014, to April 30, 2024. China is the highest productive country, while the USA had the highest number of citations. In the institution, Seoul National University in South Korea published the most articles and had the highest number of citations. Kim Jin-Tae emerged as the most prolific and influential author. BMC Anesthesiology and the Journal of Cardiothoracic and Vascular Anesthesia were identified as the most popular journals in the field. Keywords such as "atelectasis", "mechanical ventilation", and "pulmonary complications" were closely related to the use of LUS in anesthesiology.
    Conclusion: This study provides a comprehensive analysis of research on the use of LUS in anesthesiology, highlighting the growing interest in LUS and its relevance to pulmonary complications.
    Keywords:  anesthesiology; bibliometric analysis; lung ultrasound; mapping trends and hotspots
    DOI:  https://doi.org/10.2147/MDER.S492488
  9. J Periodontol. 2025 Jan 27.
    Hotspots and global trends in research of host immune response in periodontitis: A bibliometric analysis.
    Aldrin André Huamán-Mendoza, Fabiola Lucía Pantigozo-Morán, José Carlos da Silva, Casimira Valeria Chuquimez-Ventura, Marinella Holzhausen.
       BACKGROUND: The host immune response plays a major role in the pathogenesis of periodontitis. A bibliometric study can be crucial to understanding the different processes involved in this area; however, to our knowledge, it has not been published until now. Therefore, a bibliometric analysis was conducted to assess research hotspots and global trends in scientific articles about the immune response in periodontitis published between 1952 and 2023.
    METHODS: The search strategy was defined using keywords and Boolean operators. The Web of Science Core Collection database was used. In addition, the bibliometric analysis was performed using four tools: Python 3.12, VOSviewer 1.6.19, R-Bibliometrix, and CiteSpace.
    RESULTS: A total of 7696 articles were included, comprising 6691 regular articles and 1005 review articles. Data analysis revealed an increasing trend in the number of publications over the years in this field, with the most cited article written by Preshaw et al. (2012). Leading countries in article production include the United States, China, Japan, and Brazil. Regarding institutions, the University of Helsinki had the highest number of publications (N = 339), with one of its researchers being the author with the most publications (Dr. Sorsa, N = 143, H-index = 52). Concerning journals, the Journal of Periodontology was the most influential journal. Finally, recent trending topics in research were related to the influence of inflammation on dysbiosis, immune biomarkers, immunomodulation, and the impact of aging on immunocompetence.
    CONCLUSION: This bibliometric study demonstrated a growing interest and the emergence of new trends in research on host immune response in periodontitis.
    Keywords:  adaptive immunity; bibliometrics; immunity; innate; periodontal diseases; periodontitis
    DOI:  https://doi.org/10.1002/JPER.24-0473
  10. J Dent Sci. 2025 Jan;20(1): 170-177
    The literature on digital technologies for removable dental prostheses: A two-decade bibliometric analysis.
    Min-Hsun Hsu, Yu-Chao Chang.
       Background/Purpose: The advent of digital technologies has significantly transformed the current dentistry, particularly in the fabrication of removable dental prostheses. A bibliometric analysis of literature may provide a direction of research hotspots and future trends in this field.
    Materials and methods: Data were retrieved from Web of Science database for the analysis of literature on digital technologies for removable dental prostheses. Microsoft Excel was used for the descriptive statistics. VOSviewer was deployed for the analysis of published articles.
    Results: A total of 457 published documents were identified from 2004 to 2023. The most frequently published article type was original article (n = 262, 57.33%). The number of annual publications and citations significantly increased from 2004 to 2023, respectively (P for trend <0.001). In addition, the significant increased number of publications and citations pre year affected by COVID-19 pandemic were noted (P < 0.002). Most articles were published in Journal of Prosthetic Dentistry (n = 141, 30.85%). The computer-aided design (CAD)/computer-aided manufacturing (CAM) and 3D printing technique were the frequent emphasized keywords in digital technologies for removable dental prostheses.
    Conclusion: This bibliometric analysis revealed a growing research interest and technological progress in digital technologies for removable dental prostheses during past two decades. The enhancement of accuracy by CAD/CAM and 3D printing suggests a promising future for the application of these technologies in dental practice.
    Keywords:  Bibliometric analysis; Complete denture; Digital dentistry; Removable partial denture; Removable prostheses
    DOI:  https://doi.org/10.1016/j.jds.2024.08.015
  11. Acta Cardiol. 2025 Jan 28. 1-12
    Valvular heart disease and heart-related disease: a bibliometric and visual analysis from 2000 to 2023.
    Deshuang Zhao, Jing Bai.
       BACKGROUND: Previous studies have shown that valvular heart disease (VHD) is closely related to the development of heart-related disease (HRD). However, the current research for the relationship between VHD and HRD is complex and poorly targeted. Meanwhile, these studies lack the support of bibliometric analysis results.
    OBJECTIVE: Our study focused on a bibliometric analysis of published papers on the relationship between VHD and HRDs. The study also attempted to identify the primary authors, institutions and countries to analyse the status and trends of research on VHD and HRDs.
    METHODS: The PubMed database was searched for publications on VHD and HRD between 2000 and 2023. Python v3.10.8, R v4.2.2 and VOSviewer v1.6.18 software tools were utilised to perform this bibliometric analysis and visualisation.
    RESULTS: There were 4,235 qualified publications found in total, with the annual number of publications increasing. According to the analysis of the co-occurrence of keywords, we found that the main research directions are for age, gender, disease diagnosis and treatment. Newly emerging research mainly focuses on heart failure, which is relatively related to VHD.
    CONCLUSION: These results provided a useful perspective on current research and future prospects for the research on the link between VHD and HRD, which could help researchers to select partners and facilitate their research to elucidate the underlying molecular mechanisms of VHD and HRD, including the causes, prevention, and treatment.
    Keywords:  Valvular heart disease; bibliometric analysis; heart failure; heart-related disease; visual analysis
    DOI:  https://doi.org/10.1080/00015385.2025.2450983
  12. J Orthop Trauma. 2025 Jan 29.
    Analysis of the Top Articles and Authors of the Journal of Orthopaedic Trauma and Bibliometric Comparison of Impact Factors of Orthopaedic Surgery Journals.
    McKenna W Box, Troy Puga, Laurel Marsh, Wrangler Beal, Vinay Chandrasekaran, John T Riehl.
       OBJECTIVES: To determine the top 100 cited authors and the top 20 articles in the Journal of Orthopaedic Trauma (JOT) and compare its impact factor to orthopaedic and non-orthopaedic surgery literature.
    DESIGN: Review.
    METHODS: The Web of Science database was used to determine the top 100 cited authors and top 20 cited articles that originated in JOT from 1995 to the present. The total number of citations for each article and author in first, last, and any author position for publications in JOT, and the location of training and current place of work for each author were gathered. Each author's total number of citations as first author was tallied to determine the top 100 JOT first authors. The Journal Citation Reports database was searched to determine the impact factor (IF) of multiple orthopaedic and non-orthopaedic journals from 1997 to 2023. Yearly IF and yearly IF percent growth were calculated.
    RESULTS: The number of citations for the top 20 cited articles in JOT ranged from 302 to 787. Of the top 100 JOT first authors by citation number, 93 were orthopaedic surgeons. 65% of these completed a residency in the United States, 61% worked in the United States, and of the authors that work in the United States, 70.5% practice in an academic setting. From 1997 to 2023, JOT's mean yearly IF was 1.6, and the mean yearly IF percent growth was 6.1%. The mean IF for included comparison orthopaedic subspecialty journals was 2.3, with 5.6% mean yearly IF percent growth. JOT's median IF was 1.8 and was second to Injury (IF 1.9) within orthopaedic trauma journals evaluated.
    CONCLUSIONS: This bibliometric analysis shows that JOT's most cited authors are primarily U.S.-trained orthopaedic surgeons in academic environments. JOT has consistently experienced annual growth in its impact factor throughout its almost 30-year history and has one of the highest impact factors of measured orthopaedic trauma journals.
    LEVEL OF EVIDENCE: IV.
    DOI:  https://doi.org/10.1097/BOT.0000000000002964
  13. Interact J Med Res. 2025 Jan 30. 14 e63775
    Evolution of Artificial Intelligence in Medical Education From 2000 to 2024: Bibliometric Analysis.
    Rui Li, Tong Wu.
       BACKGROUND: Incorporating artificial intelligence (AI) into medical education has gained significant attention for its potential to enhance teaching and learning outcomes. However, it lacks a comprehensive study depicting the academic performance and status of AI in the medical education domain.
    OBJECTIVE: This study aims to analyze the social patterns, productive contributors, knowledge structure, and clusters since the 21st century.
    METHODS: Documents were retrieved from the Web of Science Core Collection database from 2000 to 2024. VOSviewer, Incites, and Citespace were used to analyze the bibliometric metrics, which were categorized by country, institution, authors, journals, and keywords. The variables analyzed encompassed counts, citations, H-index, impact factor, and collaboration metrics.
    RESULTS: Altogether, 7534 publications were initially retrieved and 2775 were included for analysis. The annual count and citation of papers exhibited exponential trends since 2018. The United States emerged as the lead contributor due to its high productivity and recognition levels. Stanford University, Johns Hopkins University, National University of Singapore, Mayo Clinic, University of Arizona, and University of Toronto were representative institutions in their respective fields. Cureus, JMIR Medical Education, Medical Teacher, and BMC Medical Education ranked as the top four most productive journals. The resulting heat map highlighted several high-frequency keywords, including performance, education, AI, and model. The citation burst time of terms revealed that AI technologies shifted from imaging processing (2000), augmented reality (2013), and virtual reality (2016) to decision-making (2020) and model (2021). Keywords such as mortality and robotic surgery persisted into 2023, suggesting the ongoing recognition and interest in these areas.
    CONCLUSIONS: This study provides valuable insights and guidance for researchers who are interested in educational technology, as well as recommendations for pioneering institutions and journal submissions. Along with the rapid growth of AI, medical education is expected to gain much more benefits.
    Keywords:  AI; Citespace; VOSviewer; academic pattern; artificial intelligence; bibliometric; citation trends; medical education
    DOI:  https://doi.org/10.2196/63775
  14. Orthop Surg. 2025 Jan 29.
    Global Research Hotspots and Trends in Advances of the Ilizarov Technique: A Bibliometric Mapping.
    Xinxin Wang, Fei Lu, Wenxia Wang, Xiaoyan Zhi.
       OBJECTIVE: An updated bibliometric analysis is needed to address the lack of comprehensive understanding of Ilizarov technique's research trends and hotspots, fostering collaboration and technology adoption. CiteSpace was utilized to perform co-citation analyzes on authors, countries, institutions, journals and cited journals, authors and cited literature, along with keywords. This approach aimed to identify leaders, collaborating institutions, and research hotspots associated with the Ilizarov technique, while also predicting future development trends.
    METHODS: Data relevant to Ilizarov technologies from 1994 to 2023 were extracted from Science Net's core collection. Excel was utilized to develop an exponential function for forecasting annual publication numbers. CiteSpace V5.5 was used to conduct co-citation analyzes, which included authors, countries (regions), institutions, journals, citation journals, authors, citations, and keywords. Burst detection algorithms were applied to analyze countries (regions), institutions, and keywords, with keyword clustering achieved using the logarithmic likelihood ratio.
    RESULTS: A total of 2030 studies were collected, with annual publications on the Ilizarov technique fitting an exponential model Y = 3E-37e0.0439x (R2 = 0.7979). Morasiewicz Piotr from the University of Opole in Poland emerged as the most prolific author. The leading countries included the USA and China, and notable institutions included the Egyptian Knowledge Bank and the Ilizarov National Scientific Center for Restorative Traumatology and Orthopaedic. Research outputs appeared primarily in orthopedics and surgery, with a focus on keywords such as management, the Ilizarov technique, external fixation, distraction osteogenesis, reconstruction, and the Ilizarov method.
    CONCLUSIONS: Based on current global trends, the number of publications in the Ilizarov field will continue to increase. Future studies will likely place more emphasis on advancing application concepts and device development.
    Keywords:  CiteSpace; Ilizarov; bibliometrics; visual analysis; web of science
    DOI:  https://doi.org/10.1111/os.14325
  15. World J Hepatol. 2025 Jan 27. 17(1): 96105
    Hotspots and trends in stem cell therapy for liver fibrosis and cirrhosis: A bibliometric analysis.
    Wen-Yan Zhu, Xiang Li, Jia-Ling Xie, Qin Lu, Ying-Jie Ma, Zhao-Jing Zhu, Juan Liu.
       BACKGROUND: Liver fibrosis and cirrhosis are global medical challenges that require safe and effective treatments. In the past two decades, there has been a surge in research on stem cell therapy for liver fibrosis and cirrhosis. This study aimed to conduct a comprehensive analysis of the research hotspots and trends in this field through bibliometrics.
    AIM: To conduct a bibliometric analysis on hotspots and trends in stem cell therapy for treatment of liver fibrosis and cirrhosis.
    METHODS: Publications on stem cell therapy for liver fibrosis and cirrhosis were retrieved from the Web of Science Core Collection database. The distribution and collaboration among literature, authors, countries, and institutions were analyzed visually using Excel, CiteSpace, Bibliometrix R-package, VOSviewer and Pajek software. Additionally, an investigation of keywords, burst keywords, and clusters was conducted.
    RESULTS: As of September 20, 2024, a total of 1935 documents were retrieved dating from 2004 to 2024, with 1186 strongly relevant publications obtained after screening. China, the United States, and Japan were the major contributors in this field. Cairo University, Zhejiang University and Yamaguchi University were the major institution in this field. The journal Stem Cell Research & Therapy published the most papers. There were 686 authors, with Shuji Terai, Isao Sakaida, Soon Koo Baik, and Lanjuan Li publishing the most papers. The research focused on alcoholic cirrhosis and nonalcoholic fatty liver disease. The emerging areas of interest were extracellular vesicles, exosomes, and their enriched microRNAs. The field is experiencing rapid growth due to the changing research trends and increasing literature.
    CONCLUSION: These findings provide a thorough overview of stem cell therapy in the field of liver fibrosis and cirrhosis.
    Keywords:  Bibliometrics; Cirrhosis; Exosomes; Extracellular vesicles; Liver fibrosis; Mesenchymal stromal cell; Stem cell therapy
    DOI:  https://doi.org/10.4254/wjh.v17.i1.96105
  16. Musculoskelet Surg. 2025 Jan 30.
    A bibliometric analysis of the 50 most cited articles on acromioclavicular joint reconstruction.
    L O'Dwyer, B Murphy, M S Davey, D Morrissey, J T Cassidy.
      The aim is to identify the 50 most cited papers and thus the most influential papers pertaining to ACJ reconstruction, and specifically, analysing the level of evidence (LOE), article content, journals occurring, and countries represented within the 50 most cited. A search of the Web of Science database was carried out using the following terms: "Acromioclavicular joint" OR "AC joint" (Topic) AND Reconstruction OR Repair (Topic). The top 50 relevant articles were analysed in relation to citations, citation density, geographic origin of the article, year published, and article type. The articles were cited a total of 6053 times. The most cited article was cited 347 times. The highest citation density was 20.02, with a mean citation density of 7.71 ± 4.13. Seventy per cent of the articles involved clinical research, 74% of which involved level IV evidence. Fifty-two per cent of the articles were published in the American Journal of Sports Medicine (AJSM). Most authors originated from USA (n = 26 or 52%), followed by Germany (n = 14 or 28%). This study revealed a paucity of articles with higher LOE among the most cited. Eight of the top 10 are either theoretical or biomechanical studies, and one reports an examination technique. Only two of the top 10 reported outcomes following surgical intervention and can thus directly guide treatment. Future research in the area of ACJ reconstruction should focus on generating high-quality interventional studies capable of informing/impacting patient care. Publishing in journals such as AJSM or Arthroscopy may lead to more citations.
    Keywords:  ACJ reconstruction; Bibliometric; Citation; Orthopaedic surgery; Shoulder surgery
    DOI:  https://doi.org/10.1007/s12306-025-00886-w
  17. Reumatol Clin (Engl Ed). 2025 Jan 23. pii: S2173-5743(25)00001-2. [Epub ahead of print] 101807
    Bibliometric analysis of the scientific production of rheumatology departments in Spain during the 2013-2022 period.
    Daniel Seoane-Mato, Fernando Sánchez-Alonso, Mercedes Guerra-Rodríguez, Enrique González-Dávila, Federico Díaz-González.
       BACKGROUND AND OBJECTIVE: Bibliometric studies of scientific production in Spanish Rheumatology are scarce. The aim of this study was to analyze the bibliographic production of Rheumatology Services in Spain over the period 2013-2022.
    MATERIALS AND METHODS: Original articles and reviews with the affiliation of the first or corresponding author to a Spanish rheumatology Service/Department/Section/Unit were identified in the Web of Science Core Collection and Scopus databases. Keywords and titles were used to classify articles by field (clinical, epidemiological or basic) and pathology. International collaborations and collaborations between Autonomous Communities (AC) were identified. Quantitative bibliometric indicators were obtained (number of articles published per year, pathology and AC) and impact indicators were obtained (based on the number of citations per article). The H-index was also calculated.
    RESULTS: The total number of publications was 2321, with an annual growth rate of 4.1% in the period analyzed. In 14.1% of the articles there were international collaborations, mainly with the United States and the United Kingdom, while between ACs the most numerous were between Madrid and Catalonia. The pathologies with the highest H-index were rheumatoid arthritis (RA), spondyloarthropathies (SpA), osteoarthritis and vasculitis (34, 32, 28 and 26, respectively). The H-index for the Spanish rheumatology services as a whole was 69.
    DISCUSSION AND CONCLUSIONS: The scientific production of rheumatology services/departments/sections/units in our country increased between 2013 and 2022. By pathology, the scientific production in RA and SpA stands out.
    Keywords:  Bibliometrics; Bibliometría; España; Produccion científica; Reumatología; Rheumatology; Scientific production; Spain
    DOI:  https://doi.org/10.1016/j.reumae.2025.101807
  18. World J Gastrointest Surg. 2025 Jan 27. 17(1): 100291
    Minimally invasive pancreaticoduodenectomy: A bibliometric method applied to the top one hundred cited articles.
    Jia-Jie Feng, Yi-Wen Zhao, Hong-Yin Liang, Ke-Xin Jiang, Rui-Wu Dai.
       BACKGROUND: Minimally invasive pancreaticoduodenectomy (MIPD) is considered one of the most complex procedures in general surgery. The number of articles on MIPD has been increasing annually. However, published reports often have complex research directions, and the focal points frequently change. Therefore, a comprehensive review and organization of the literature in this field is necessary.
    AIM: To summarize current research, predict future hotspots and trends, and provide insights for MIPD development.
    METHODS: To conduct the study, the Web of Science Core Collection was searched for relevant articles. The analysis focused on the top 100 articles in the field. Two widely used bibliometric tools, CiteSpace and VOSviewer, were used to examine various aspects, including research directions, authors, countries, institutions, journals, and keywords.
    RESULTS: The top 100 articles were published between 2005 and 2022, with the majority originating from the United States (n = 51). Among the contributing institutions, Pancreas Center of the University of Chicago and the Health System of the University of Chicago had the highest number of publications (n = 17). In terms of individual authors, "Zeh HJ" and "Zureikat AH" led with 13 articles each. The high-frequency keywords in the literature encompassed three main areas: Surgical modality, perioperative outcomes, and the learning curve. These keywords were further categorized into seven primary clusters, with the largest being "laparoscopic pancreaticoduodenectomy".
    CONCLUSION: The most influential studies predominantly originate from the United States, and there is growing interest in robotic surgery. Despite MIPD's potential benefits, further research is required to address technical challenges and improve outcomes.
    Keywords:  Bibliometric analysis; Citation analysis; Laparoscopic surgery; Minimally invasive pancreatoduodenectomy; Robotic surgery
    DOI:  https://doi.org/10.4240/wjgs.v17.i1.100291
  19. Front Immunol. 2024 ;15 1519498
    A bibliometric study on the impact of gut microbiota on the efficacy of immune checkpoint inhibitors in cancer patients: analysis of the top 100 cited articles.
    Ziqi Zhao, Kun Xu, Boqian Hu, Yizhuo Jiang, Xisheng Xu, Yuliang Liu.
       Background: Immune checkpoint inhibitors (ICIs) have transformed oncological treatment by modulating immune responses against tumors. However, their efficacy is subject to inter-patient variability and is associated with immune-related adverse events (irAEs). The human gut microbiota, a complex microbial ecosystem, is increasingly implicated in modulating responses to ICIs. This bibliometric analysis examines the 100 most-cited articles to elucidate trends and advancements in research concerning the gut microbiota's impact on ICI efficacy.
    Methods: A systematic literature retrieval was conducted within the Web of Science Core Collection (WoSCC), focusing on the 100 most-cited articles. VOSviewer and CiteSpace were utilized for bibliometric analysis, examining collaborative patterns and keyword co-occurrences. The relationship between citing and cited entities was analyzed, and burst ranking identified research hotspots based on citation frequency.
    Results: The 100 most-cited publications encompassed a range of disciplines, with a predominance of oncological research. The United States and China were leading in publication volume, with France and Canada also contributing significantly. French institutions, particularly INSERM and Université Paris Cite, were prolific. Routy, Bertrand and Zitvogel, Laurence were prominent among high-impact authors. Dominant keywords included "gut microbiota," "immunotherapy," "efficacy," and "cancer." The article by Routy et al. (2018) was the most frequently cited.
    Conclusions: This study highlights the significant role of the gut microbiota in ICI development and efficacy, emphasizing the necessity for international and interdisciplinary collaboration. The research is progressively focusing on managing immunotherapy side effects and optimizing treatment strategies. Challenges, including individual variability in gut microbiota composition, persist. Further research is imperative to exploit the potential of the gut microbiota in cancer therapy, advocating for personalized approaches and a more profound comprehension of the underlying mechanisms.
    Keywords:  bibliometrics analysis; cancer patients; gut microbiota; immune checkpoint inhibitors; immunotherapy
    DOI:  https://doi.org/10.3389/fimmu.2024.1519498
  20. Sudan J Paediatr. 2024 ;24(2): 114-124
    Orofacial cleft research in Nigeria: a bibliometric analysis.
    Kehinde Kazeem Kanmodi, Jacob Njideka Nwafor, Lawrence Achilles Nnyanzi, Afeez Abolarinwa Salami.
      Orofacial cleft (OC) is a group of heterogeneous congenital abnormalities affecting the orofacial region. All over the world, several studies have been conducted on OC. This study aims to analyze OC research outputs in Nigeria. A SCOPUS-based bibliometric analysis of OC research outputs in Nigeria was done. A total of 130 outputs, of which 90% were articles, published within a 5-2-year (1970-2022) interval were identified. These publications had a total of 1,145 citations with a h-index of 19. There was skewedness in the geopolitical distribution and ownership of Nigerian institutions engaged in OC research; the majority of which were owned by the federal government and situated in the southern parts of Nigeria. The University of Lagos was the Nigerian institution with the highest frequency (n = 52) of outputs on OC research. Adeyemo WL was the Nigerian researcher with the highest: number of publications on OC (n = 46), h-index (n = 11) and citations on OC publications (n = 474). Half of the top ten overseas institutions having researchers collaborating with OC researchers in Nigerian institutions were based in the USA. All the institutions funding OC research in Nigeria were foreign and predominantly in the USA. The majority of the 10 most-cited OC outputs from Nigerian institutions were first authored by foreign researchers. There is a need to locally strengthen OC research capacity in Nigeria, especially in the area of funding, and institutional strengthening.
    Keywords:  Bibliometric analysis; Nigeria; Orofacial cleft; Research
    DOI:  https://doi.org/10.24911/SJP.106-1653545752
  21. Perioper Med (Lond). 2025 Jan 30. 14(1): 12
    Global research trends in music therapy for surgery: a bibliometric analysis (2009-2023).
    Xiaoping Xu, Zhenglan Zhong, Yong Yi.
      Music therapy, known for its profound impact on human emotions and physiology, has gained increasing attention for its applications in medical settings, particularly in surgery. This study conducted a bibliometric analysis of publications on the application of music therapy in surgery from 2009 to 2023, utilizing the Web of Science Core Collection (WoSCC) as the primary database. A total of 479 publications were analyzed using VOSviewer, CiteSpace, Microsoft Excel, and online bibliometric tools. Findings indicate a steady increase in annual publications since 2009, peaking in 2021. The USA leads global research efforts with 31.7% of publications, followed by China (17.7%) and Italy (10%). Harvard University was identified as the top contributing institution, while the Journal of Perianesthesia Nursing was the primary publishing journal, and the Cochrane Database of Systematic Reviews was the highest co-cited journal. Cao Hua contributed the most publications, and Nilsson U was identified as the most co-cited author (n = 131). Keyword analysis highlighted anxiety, therapy, music therapy, and pain as primary research trends. This study provides valuable insights into the evolving landscape of music therapy research in surgical contexts. Future efforts should focus on expanding interdisciplinary collaborations, exploring advanced technologies for personalized interventions, and investigating optimal implementation strategies to enhance the integration of music therapy into surgical practice.
    Keywords:  Bibliometric analysis; CiteSpace; Music therapy; Surgery; VOSviewer
    DOI:  https://doi.org/10.1186/s13741-025-00496-x
  22. Heliyon. 2025 Jan 15. 11(1): e41663
    International youth football research developments: A CiteSpace-based bibliometric analysis.
    Wenlu Yu, Wengao Liao, Ya Zhong, Yishi Guan.
      With the vigorous development of football, research on youth football has garnered significant attention from scholars, leading to an increase in published findings. However, there is currently no comprehensive retrospective study that examines the status, hotspots, and trends of research in this field. This study employed Cite Space, a visual bibliometric software, to systematically review and analyze 1637 articles from the Web of Science (WOS) and China Knowledge Infrastructure Project (CNKI) databases up to January 2024. The primary objective was to examine the sources, authors, institutions, regions, citations, as well as keywords, and clustering of these articles to identify the global research hotspots and trends in youth football. The study concluded that the number of research articles in this field has been decreasing annually, and the research hotspots are exhibiting a gradual downward trend. The primary research institutions are comprehensive universities, supplemented by research centers and hospitals. The United States, the United Kingdom, Spain, and China have produced substantial research results in this area, and collaboration among researchers is relatively strong, indicating a positive development trajectory. Current research hotspots include sports monitoring and evaluation, sports injury and risk, talent identification and development, sports performance, the integration of sports and education, school football, and youth training systems. This finding provides a comprehensive overview of the research landscape in this field and presents opportunities for researchers to pursue further in-depth investigations.
    Keywords:  Bibliometrics; CiteSpace; Research dynamics; Youth football
    DOI:  https://doi.org/10.1016/j.heliyon.2025.e41663
  23. Int J Surg. 2025 Jan 24.
    Global trends in surgically based treatment of anal fistula in Crohn's disease: a bibliometric and visualization analysis.
    Xingtao Jin, Ye Han, Min Yang, Qianqian Ye, Qingming Wang, De Zheng, Zubing Mei.
       BACKGROUND: Crohn's disease (CD) is a chronic, recurrent gastrointestinal disorder characterized by a complex etiology. Among its perianal complications, anal fistulas represent a challenging comorbidity. With the increase of surgical options, a comprehensive bibliometric analysis was deemed necessary to consolidate the vast array of research in this field.
    METHODS: We extracted 1608 articles spanning from 1 January 1994, to 1 May 2024, from the Web of Science Core Collection. Using VOSviewer, CiteSpace, and Scimago Graphica for visual analytics, we synthesized key trends across multiple bibliometric indicators, encompassing geographic and institutional contributions, individual authorship, journal prominence, citation metrics, and thematic prevalence.
    RESULTS: From the delineated corpus, we identified publications from 325 countries and 5110 research institutions, with the US and UK at the forefront of publication volume and academic impact. The data indicated a leading role for institutions like the Cleveland Clinic and Imperial College London. "Diseases of the Colon and Rectum" emerged as a central journal due to its high publication and citation frequency. Distinctly, the analysis uncovered trending keywords, signifying the field's prioritization on surgical intervention, biologic therapy, imaging modalities, and emerging biological treatments.
    CONCLUSION: Our findings elucidate a trajectory toward prominent advancements in CD fistula research. This analysis underscores the field's shift towards integrative treatment strategies, spotlighting the pressing need for comprehensive comparative studies of surgical approaches. It underscores the imperative for robust clinical trials to standardize treatments and extend care to a broader CD patient population.
    DOI:  https://doi.org/10.1097/JS9.0000000000002238
  24. Obes Rev. 2025 Jan 28. e13888
    Exploring the progress and trends of immunotherapy for type 1 diabetes: A comprehensive bibliometric analysis spanning nearly two decades.
    Yixin Jiang, Zhou Xu, Yuting Wu, Xinglei Li, Jitao Ling, Yixuan Chen, Zicheng Zhu, Pingping Yang, Xiao Liu, Deju Zhang, Jianping Liu, Xiaoping Yin, Jing Zhang, Peng Yu.
       INTRODUCTION: Immunotherapy is a crucial treatment for type 1 diabetes (T1D), yet analyses focusing on research priorities and trends in this field are limited. Therefore, this study employs bibliometric methods to systematically explore the current research status of immunotherapy for T1D.
    METHODS: Based on the Web of Science Core Collection Database, 1573 articles and review articles related to immunotherapy for T1D published from 2004 to 2023 were screened for bibliometric analysis. VOSviewer, CiteSpace, and R software were applied to comprehensively analyze the number of publications, journals, countries, authors, institutions, keywords, and references.
    RESULTS: In the past two decades, the global annual publication rate has seen a significant increase of 238.24%. Almost 40% of all publications have appeared in the last 5 years, accounting for over 50% of total citations. Journals such as Diabetes, Journal of Autoimmunity and Frontiers in Immunology have exerted substantial influence. Collaboration across nations has been notably strong, with the United States leading the way. The University of Florida is the most productive institution. Terms like "nivolumab," "ipilimumab," "pembrolizumab," and "immune checkpoint inhibitor(s)" gain considerable traction. The majority of research has clustered around themes such as immunomodulation, autoimmune diseases, immune checkpoint inhibitors, mesenchymal stem cells, and cell therapy. Precision medicine, immune checkpoint inhibitors, and nanotechnology are trending focal points in contemporary research.
    CONCLUSION: The outcomes of the study are instrumental in enabling scholars to comprehend the evolving trajectory of immunotherapeutic approaches for T1D and facilitate the swift recognition of emerging research pathways.
    Keywords:  bibliometric analysis; immune checkpoint inhibitor; immunotherapy; type 1 diabetes; visualization
    DOI:  https://doi.org/10.1111/obr.13888
  25. Front Immunol. 2024 ;15 1512349
    Top 100 most-cited articles on apoptosis of non-small cell lung cancer over the past two decades: a bibliometrics analysis.
    Leshi Ma, Jing Zhang, Zi Dai, Pei Liao, Jieshan Guan, Zhijie Luo.
       Background: Recently there has been an increasing number of studies have explored apoptosis mechanisms in lung cancer (LC). However, no researchers have conducted a bibliometric analysis of the most cited articles in this field.
    Objective: To examine the top 100 most influential and cited publications on apoptosis in non-small cell lung cancer (NSCLC) from 2004 to 2023, summarizing research trends and key focus areas.
    Methods: This study utilized the Web of Science Core Database (WOSCC) to research NSCLC apoptosis from 2004 to 2023, using keyword selection and manual screening for article searches. Bibliometrix package of R software 4.3.1 was used to generate distribution statistics for the top ten institutions, journals and authors. Citespace6.2. R6 was used to create the visualization maps for keyword co-occurrence and clustering. VOSviewer1.6.19 was used to conduct cluster analysis of publishing countries (regions), with data exported to SCImago Graphica for geographic visualization and cooperation analysis. VOSviewer1.6.19 was used to produced co-citation maps of institutions, journals, authors, and references.
    Results: From 2004 to 2023, 13316 articles were retrieved, and the top 100 most cited were chosen. These were authored by 934 individuals from 269 institutions across 18 countries and appeared in 45 journals. Citations ranged from 150 to 1,389, with a median of 209.5. The most influential articles appeared in 2005 and 2007 (n=13). The leading countries (regions), institutions, journals and authors were identified as the United States (n=60), Harvard University (n=64), CANCER RESEARCH (n=15), SUN M and YANG JS (n=6). The top five keywords were "expression", "activation", "apoptosis", "pathway" and "gefitinib". This study indicates that enhancing apoptosis through circular RNA regulation and targeting the Nrf2 signaling pathway could become a key research focus in recent years.
    Conclusion: Apoptosis has been the subject of extensive research over many years, particularly in relation to its role in the pathogenesis, diagnosis, and treatment of NSCLC. This study aims to identify highly influential articles and forecast emerging research trends, thereby offering insights into novel therapeutic targets and strategies to overcome drug resistance. The findings are intended to serve as a valuable reference for scholars engaged in this field of study.
    Keywords:  apoptosis; bibliometrics; cited articles; non-small cell lung cancer; visual analysis
    DOI:  https://doi.org/10.3389/fimmu.2024.1512349
  26. J Interferon Cytokine Res. 2025 Jan 28.
    Research Hotspots of Interferon Gamma in the Treatment of Lung Cancer: A Bibliometric Analysis Based on CiteSpace.
    Zhen Lv, Jianjun Wu.
      Interferon-gamma (IFN-γ) is an important cytokine associated with antitumor immunity and has been implicated in the pathogenesis and progression of lung cancer. Nevertheless, no bibliometric analyses have been published in this field to date, and thus we aim to address this gap in knowledge. A search of the Web of Science (WOS) for literature related to the treatment of lung cancer with IFN-γ was conducted from 2002 to 2024. The extracted information from the included articles was subjected to visual analysis, and network diagrams were generated using software such as CiteSpace and VOSviewer. In total, 589 articles related to the treatment of lung cancer with IFN-γ were included in WOS between 2002 and 2024. The number of articles and citation frequency generally showed an increasing trend year by year. The United States and the University of California are the countries and institutions with the largest number of articles. The researcher who made the largest contribution to this field was Xin Cai from China (6). The Journal for ImmunoTherapy of Cancer published the largest number of relevant papers in the field (16 papers, IF = 12.469). The research hotspots in the field of immune escape in recent years have been IFN-γ, mechanism, immune checkpoints, and microtumor inhibitors. The field of IFN-γ treatment of lung cancer is evolving at a rapid pace. The current research focus within this field is on elucidating the mechanism of IFN-γ treatment of lung cancer, investigating the role of immune checkpoint inhibitors, and examining the tumor microenvironment and other pertinent topics.
    Keywords:  bibliometrics; interferon-gamma; lung cancer; research status CiteSpace; visualization analysis
    DOI:  https://doi.org/10.1089/jir.2024.0242
  27. Front Oncol. 2024 ;14 1493996
    Research progresses and hotspots on glucose metabolic reprogramming in breast cancer: a bibliometric analysis over the past two decades.
    Lei Huang, Wenyue Zhao, Lamei Sun, Dong Niu, Xiaodan Zhu, Chunhui Jin.
       Background: Abnormal energy metabolism is a prominent characteristic of cancers. Increasing evidence has suggested the involvement of glucose metabolism reprogramming in the progression of breast cancer (BC). This article aims to provide a comprehensive overview of glucose metabolism reprogramming in BC through a bibliometric analysis.
    Methods: Relevant literatures published from 2004 to 2024 were searched in the Web of Science Core Collection database, and a bibliometric analysis was conducted using VOSviewer, CiteSpace, and Bibliometrix.
    Results: In total, 957 publications reporting glucose metabolism reprogramming in BC were included, showing an increasing trend in the annual publication outputs. China ranked first in publication outputs, and the United States of America (USA) had a dominant place in citation counts. The research achievements of Thomas Jefferson University in the USA were at the forefront and widely cited. Lisanti, Michael P., and Sotgia, Federica were the most productive authors. Keyword analysis suggested that the mechanisms of glucose metabolism reprogramming in BC and related therapeutic strategies were the research hotspots.
    Conclusion: This study, for the first time, elucidated the progresses and hotspots of in the research on glucose metabolism reprogramming in BC, highlighting its potential role in treating BC. Considering that the glycolytic reprogramming of BC is a complex biological process, it is imperative for countries to enhance cooperation in the pursuit of effective antimetabolic therapies to overcome challenges in BC treatment.
    Keywords:  antimetabolic therapy; bibliometrics; breast cancer; glucose metabolism reprogramming; tumor microenvironment
    DOI:  https://doi.org/10.3389/fonc.2024.1493996
  28. Front Cell Neurosci. 2024 ;18 1521398
    Bibliometric insights into astrocytic roles in depression and treatment.
    Linsun Lin, Ziyi Guo, Zhuoyu Ren, Yanchen Feng, Peigang Fang, Tao Wang, Min Chen.
       Objective: Depression is a mental disorder that significantly impairs both physical and mental health. Recent studies have shown that reactive astrogliosis have gained significant attention for their involvement in the pathophysiology of depression. However, there is no bibliometric analysis in this research field. This study aims to provide a comprehensive overview of the knowledge structure and research hotspots regarding the role of astrocytes in the mechanisms and treatment of depression through bibliometric analysis. The scope of the literature review encompasses both basic and clinical research.
    Methods: Publications related to astrocytes in depression and treatment from 2014 to 2023 were searched in the Web of Science Core Collection (WoSCC) database. VOSviewer, CiteSpace, and the R package "bibliometrix" were used to conduct this bibliometric analysis.
    Results: From 2014 to 2023, a total of 1,502 documents from 78 countries on astrocytes in depression and treatment were analyzed from 169 journals, with the most co-cited journals being the Journal of Neuroscience and PNAS. China Medical University was the most productive institution. The analysis identified key authors like Verkhratsky Alexei and Baoman Li, and major co-cited references by Rajkowska and Liddelow. Keywords such as "synaptic plasticity," "astrocytes," and "neuroinflammation" revealed research trends focusing on molecular mechanisms, gut microbiota, and inflammation.
    Conclusion: This is the first bibliometric study to comprehensively summarize the research trends and advancements regarding astrocytes in depression and its treatment. Through this bibliometric analysis, we aim to enhance the understanding of the significance of astrocytes in depression research and provide new perspectives and insights for future investigations. We hope that this study will facilitate a broader integration of basic and clinical research, offering novel approaches for the treatment of depression.
    Keywords:  CiteSpace; VOSviewer; astrocyte; bibliometric; depression
    DOI:  https://doi.org/10.3389/fncel.2024.1521398
  29. J Cancer Res Clin Oncol. 2025 Jan 24. 151(2): 47
    Bibliometric analysis of liposarcomas treatment from 2004 to 2023.
    Xiaopeng Wang, Jingjing Ye, Daoning Liu, Liang Yan, Shuquan Li, Ang Lv, Chengpeng Li, Jianhui Wu, Hui Qiu, Chunyi Hao.
       BACKGROUND: Liposarcomas are mesenchymal malignant tumors characterized by varying degrees of adipocytic differentiation that comprises approximately 20% of soft tissue sarcomas. Despite advancements in this field, there remains a need for a comprehensive understanding of the mechanisms, diagnosis, and treatment of liposarcomas. Currently, there is a lack of bibliometric surveys on the development trajectory of liposarcomas treatment, research hotspots, and author and team collaboration.
    METHODS: In this study, we obtained publications from the Web of Science database from 2004 to 2023, with a specific focus on the treatment of liposarcomas. By utilizing bibliometric methods, the data were processed to facilitate visual analysis of various aspects, including authors, countries, institutions, cocitations, keywords, references, and gene characteristics.
    RESULTS: The number of publications on liposarcomas treatment has increased over the past two decades, from 39 in 2004 to 232 in 2023, with the United States of America contributing the most publications. Among the institutions, the Memorial Sloan Kettering Cancer Center had the highest volume of 87 publications. Notably, Alessandro Gronchi published 63 articles on the treatment of liposarcomas in the last 20 years. Cancers is the journal with the highest number of 57 publications. High-frequency keywords in these publications included "soft tissue sarcoma", "liposarcoma", "retroperitoneal sarcoma", "surgery", "dedifferentiated liposarcoma", "trabectedin" and "radiotherapy". Recent trends, identified through strong citation bursts from 2020 to 2023, include next-generation sequencing, radiotherapy, and patient-derived cell lines. High-frequency genes in the liposarcomas treatment field include TP53, MDM2, CDK4, DDIT3, and CD274.
    CONCLUSIONS: The treatment of liposarcomas has garnered increasing attention worldwide in the last 20 years. The treatment approach has shifted from surgical resection to multidisciplinary therapy. The molecular and biological characteristics of different tumor subtypes have attracted more research attention, providing an important reference for the choice of treatment. The findings of this study contribute to providing a comprehensive understanding of liposarcomas treatment among researchers. Moreover, they offer valuable perspectives that can guide future research.
    Keywords:  Bibliometric analysis; Liposarcomas; Treatment; Visualized analysis
    DOI:  https://doi.org/10.1007/s00432-025-06094-0
  30. Front Endocrinol (Lausanne). 2024 ;15 1451954
    Global research hotspots and trends in oxidative stress-related diabetic nephropathy: a bibliometric study.
    Xiao-Rong Wang, Zeng Wu, Tong-Tong He, Xiao-Han Chen, Xiao-Fei Jin, Chun-Yue Zuo, Shao-Ze Yang, Yu Gao, Xiao-Hong Zhou, Wei-Juan Gao.
       Background: Oxidative stress is widely acknowledged as a key pathogenic mechanism in diabetic nephropathy (DN). In recent years, the role of oxidative stress in DN has garnered increasing attention. However, no bibliometric analysis has yet been conducted on the relationship between oxidative stress and DN. This study aims to systematically analyze the relevant literature, identify trends in research, assess current hotspots, and predict future directions.
    Methods: We retrieved literature related to oxidative stress and DN from the Web of Science Core Collection database. We analyzed data on publication volume, countries/regions, institutions, journals, keywords, and other relevant metrics using VOSviewer, the Bibliometrix R package, and CiteSpace.
    Results: From 2014 to 2024, a total of 4076 publications related to oxidative stress and DN were published across 755 journals, showing a consistent upward trend each year. China and the United States are the leading contributors in this field and demonstrate close collaborative efforts. The top contributors by country, institution, journal, and author include: China (1919 publications), Jilin University and Central South University (69 publications each), BIOMEDICINE & PHARMACOTHERAPY (117 publications), and Prof. Sun Lin (33 publications). The most frequent keyword is "oxidative stress" (3683 occurrences). In the co-citation analysis, Alicic RZ's 2017 study was the most cited (144 citations). These findings highlight the critical importance of investigating the pathogenesis of DN from the oxidative stress perspective.
    Conclusion: This study demonstrates a steady increase in research on oxidative stress in DN since 2014, highlighting its central role in the pathogenesis of DN. Future research should focus on the molecular mechanisms of oxidative stress in DN and explore its therapeutic potential, to provide new strategies for the prevention and treatment of DN.
    Keywords:  Bibliometrix R package; CiteSpace; VOSviewer; diabetic nephropathy; oxidative stress
    DOI:  https://doi.org/10.3389/fendo.2024.1451954
  31. Hum Vaccin Immunother. 2025 Dec;21(1): 2440203
    Opportunities and challenges of immuno-oncology: A bibliometric analysis from 2014 to 2023.
    Siqi Zhang, Lina Miao, Xiaoxia Tian, Bingxu Yang, Baoping Luo.
      The emergence of immuno-oncology (IO) has led to revolutionary changes in the field of cancer treatment. Despite notable advancements in this field, a thorough exploration of its full depth and extent has yet to be performed. This study provides a comprehensive overview of publications pertaining to IO. Publications on IO from 2014 to 2023 were retrieved by searching the Web of Science Core Collection database (WoSCC). VOSviewer software and Citespace software were used for the visualized analysis. A total of 1,874 articles have been published in the IO domain. The number of publications and citations has been increasing annually. This study also examines the primary research directions within the field of IO. In conclusion, this study offers a comprehensive overview of the opportunities and challenges associated with IO, illuminating the current status of research and indicating potential future trajectories in this rapidly progressing field. This study provides a comprehensive survey of the current research status and hot spots within the field of IO. It will assist researchers in comprehending the current research emphasis and development trends in this field and offers guidance for future research directions.
    Keywords:  CiteSpace; Immuno-oncology; bibliometrics; immunotherapy; visual analysis
    DOI:  https://doi.org/10.1080/21645515.2024.2440203
  32. Int Orthop. 2025 Jan 30.
    A scientometric analysis of highly cited papers in Indian spine research (1995-2024): navigating the impact.
    Raju Vaishya, Shanmuganathan Rajasekaran, Brij Mohan Gupta, Ghouse Modin Mamdapur, Mallikarjun Kappi, Abhishek Vaish.
       PURPOSE: The spine research within India has seen significant advancement, yet detailed examinations of its impact and evolution still need to be made sparse. To conduct a comprehensive scientometric review of the most frequently cited papers in Indian spine research from 1995 to 2024, aiming to map the field's evolution and its global impact.
    METHODS: Utilizing the Scopus database, a search was performed with keywords related to spine research, identifying 105 highly cited papers. This study focused on trends in publications, document types, affiliations, collaboration networks, and citation patterns.
    RESULTS: The period between 2005 and 2014 saw a significant increase in publications, with a notable emphasis on international collaborations, especially with the United States and Canada. Clinical research, particularly on the lumbar spine and surgical advancements, emerged as the primary focus. The average citations per document stood at 102.37, with original research articles constituting 73.33% of the total. Collaboration spanned across 31 countries, with the United States being the foremost partner. Indian institutions like Ganga Hospital, Coimbatore, and the All India Institute of Medical Science, New Delhi, were among the top contributors. Indian authors, notably with S. Rajasekaran leading, followed by AK Jain.
    CONCLUSION: The findings highlght the pivotal role of Indian spine research in contributing to the global knowledge base, highlighting significant areas of strength and opportunities for future research. The study offers valuable insights for researchers, policymakers, and healthcare planners, aiming to enhance spinal health care in India and internationally.
    Keywords:  Collaboration; Highly cited papers; India; Scientometrics; Spine research
    DOI:  https://doi.org/10.1007/s00264-025-06426-2
  33. Front Neurol. 2024 ;15 1510522
    The global research of magnetic resonance imaging in Alzheimer's disease: a bibliometric analysis from 2004 to 2023.
    Xiaoyu Sun, Jianghua Zhu, Ruowei Li, Yun Peng, Lianggeng Gong.
       Background: Alzheimer's disease (AD) is a common neurodegenerative disorder worldwide and the using of magnetic resonance imaging (MRI) in the management of AD is increasing. The present study aims to summarize MRI in AD researches via bibliometric analysis and predict future research hotspots.
    Methods: We searched for records related to MRI studies in AD patients from 2004 to 2023 in the Web of Science Core Collection (WoSCC) database. CiteSpace was applied to analyze institutions, references and keywords. VOSviewer was used for the analysis of countries, authors and journals.
    Results: A total of 13,659 articles were obtained in this study. The number of published articles showed overall exponential growth from 2004 to 2023. The top country and institution were the United States and the University of California System, accounting for 40.30% and 9.88% of the total studies, respectively. Jack CR from the United States was the most productive author. The most productive journal was the Journal of Alzheimers Disease. Keyword burst analysis revealed that "machine learning" and "deep learning" were the keywords that frequently appeared in the past 6 years. Timeline views of the references revealed that "#0 tau pathology" and "#1 deep learning" are currently the latest research focuses.
    Conclusion: This study provides an in-depth overview of publications on MRI studies in AD. The United States is the leading country in this field with a concentration of highly productive researchers and high-level institutions. The current research hotspot is deep learning, which is being applied to develop noninvasive diagnosis and safer treatment of AD.
    Keywords:  Alzheimer’s disease; CiteSpace; VOSviewer; bibliometric; magnetic resonance imaging
    DOI:  https://doi.org/10.3389/fneur.2024.1510522
  34. Front Med (Lausanne). 2024 ;11 1492396
    Study based on bibliometric analysis: potential research trends in fluid management for sepsis.
    Sihan Liu, Haoting Pei, Jing Wang, Lujun Qiao, Hao Wang.
       Objective: To investigate the potential and evolving trends in fluid management for patients with sepsis, utilizing a bibliometric approach.
    Methods: Scholarly articles pertaining to fluid therapy for sepsis patients were extracted from the Web of Science (WoS) database as of June 1, 2024. The R software package, "Bibliometrix," was utilized to scrutinize the primary bibliometric attributes and to construct a three-field plot to illustrate the relationships among institutions, nations, and keywords. The VOSviewer tool was employed for author analysis, keyword co-occurrence analysis, and data visualization. Additionally, CiteSpace was used to calculate citation bursts and keywords.
    Results: A comprehensive retrieval from the Web of Science (WoS) database yielded a total of 2,569 publications. The majority of these articles were predominantly published by two countries, namely the United States (US) and China. Among the myriad of journals, Critical Care and Journal for Intensive Care Medicine emerged as the most prolific. In terms of institutional contribution, the University of California System stood out as the most productive. Recent analysis of keywords revealed a significant citation burst for terms such as "balanced crystalloids" and "critically ill children".
    Conclusion: There is a growing focus on the connection between fluid management and the treatment of sepsis, with research in this area being at an advanced stage.
    Keywords:  CiteSpace; R software package; VOSviewer; bibliometric; fluid management; hotspots; sepsis
    DOI:  https://doi.org/10.3389/fmed.2024.1492396
  35. Chronobiol Int. 2025 Jan 31. 1-13
    Bibliometric analysis of global research status and trends of circadian rhythms in cancer from 2004 to 2024.
    Zhihong Chen, Shitao Jiang, Yaoge Liu, Ting Zhang, Han Zheng, Yunhan Mao, Lei Zhang, Yiyao Xu, Xin Lu.
      Research linking circadian dysregulation to cancer development has received increasing attention recently. However, a comprehensive understanding of research hotspots and trends in this area remains limited. International studies on the circadian rhythms in cancer were retrieved and downloaded from the Web of Science database. Bibliometric analysis and visualization were performed using VOSviewer, CiteSpace, and HistCite. Three thousand three hundred and eighteen English articles from 2004 to 2024 were screened and evaluated. The increase in publications and citations reflected the rapid expansion of the field. Scholars and institutions in the United States have relatively high academic productivity and impact. Chronobiology International is the most popular journal. Key clustering analysis identified six themes: biochemistry and molecular biology, physiology and immunomodulation, night shift work and health effects, physiological and mental health, tumor therapy research, and oxidative stress and cancer-related mechanisms. Keyword burst analysis identified the regulation of circadian rhythms on cells and tumor microenvironment as the research frontiers. The role of circadian rhythms in tumor immunotherapy was a current research hotspot identified by reference co-citation clustering analysis. This study reveals the current status of research on the circadian rhythms in cancer and predicts future trends. These findings provide new ideas for developing novel cancer prevention and treatment strategies.
    Keywords:  Circadian rhythm; CiteSpace; HistCite; VOSviewer; bibliometric analysis; cancer
    DOI:  https://doi.org/10.1080/07420528.2025.2456560
  36. Front Pharmacol. 2024 ;15 1507574
    Ferroptosis in kidney disease: a bibliometric analysis from 2012 to 2024.
    Yuxin Hu, Jingyi Tang, Hanzhang Hong, Yexin Chen, Beibei Ye, Ziheng Gao, Gegongming Zhu, Lin Wang, Weijing Liu, Yaoxian Wang.
       Background and aims: Ferroptosis, a novel concept of programmed cell death proposed in 2012, in kidney disease, has garnered significant attention based on evidence of abnormal iron deposition and lipid peroxidation damage in the kidney. Our study aim to examine the trends and future research directions in the field of ferroptosis in kidney disease, so as to further explore the target or treatment strategy for clinical treatment of kidney disease.
    Material and Methods: A thorough survey using the Web of Science Core Collection, focusing on literature published between 2012 and 2024 examining the interaction between kidney disease and ferroptosis was conducted. VOSviewer, CiteSpace, and Biblioshiny were used for in-depth scientometric and visualized analyses.
    Results: From 2012 to 2024, a total of 2,244 articles met the inclusion criteria for final analysis. The number of annual publications in this area of study showed a steady pattern at the beginning of the decade. The top 3 journals with the highest publication output were Renal Failure, Oxidative Medicine And Cellular Longevity, and Biomedicine & Pharmacotherapy. China and the United States had the highest number of publications. Central South University and Guangzhou Medical University as the most active and influential institutions. Documents and citation analysis suggested that Andreas Linkermann, Jolanta Malyszko, and Alberto Ortiz are active researchers, and the research by Scott J. Dixon and Jose Pedro Friedmann Angeli, as the most cited article, are more important drivers in the development of the field. Keywords associated with glutathione, lipid peroxidation, and nitric oxide had high frequency in the early studies. In recent years, however, there has been a shift towards biomarkers, inflammation and necrosis, which indicate current and future research directions in this area.
    Conclusion: The global landscape of the ferroptosis research in kidney disease from 2012 to 2024 was presented. Basic research and mechanism exploration for renal fibrosis and chronic kidney disease may be a hot spot in the future.
    Keywords:  bibliometric analysis; ferroptosis; hotspots; kidney; kidney disease; trends
    DOI:  https://doi.org/10.3389/fphar.2024.1507574
  37. World J Hepatol. 2025 Jan 27. 17(1): 102034
    Research hotspots and trends in gut microbiota and nonalcoholic fatty liver disease: A bibliometric study.
    Cai-Yun Huang, Zhong-Zhi Luo, Wei-Ping Huang, Li-Ping Lin, You-Ting Yao, Han-Xu Zhuang, Qiu-Yong Xu, Ya-Dong Lai.
       BACKGROUND: Recent research indicates that the intestinal microbial community, known as the gut microbiota, may play a crucial role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). To understand this relationship, this study used a comprehensive bibliometric analysis to explore and analyze the currently little-known connection between gut microbiota and NAFLD, as well as new findings and possible future pathways in this field.
    AIM: To provide an in-depth analysis of the current focus issues and research developments on the interaction between gut microbiota and NAFLD.
    METHODS: In this study, all data were collected from the Web of Science Core Collection, and the related searches were completed on one day (February 21, 2024). The data were stored in plain text format to facilitate subsequent analysis. VOSviewer 1.6.20 and CiteSpace 6.1R6 Basic were used for knowledge graph construction and bibliometric analysis.
    RESULTS: The study included a total of 1256 articles published from 2013 to 2023, and the number of published papers demonstrated an upward trend, reaching a peak in the last two years. The University of California, San Diego held the highest citation count, while Shanghai University of Traditional Chinese Medicine in China led in the number of published works. The journal "Nutrients" had the highest publication count, while "Hepatology" was the most frequently cited. South Korean author Suk Ki Tae was the most prolific researcher. The co-cited keyword cluster labels revealed ten major clusters, namely cortisol, endothelial dysfunction, carbohydrate metabolism, myocardial infarction, non-alcoholic steatohepatitis, lipotoxicity, glucagon-like peptide-1, non-islet dependent, ethnicity, and microRNA. Keyword outbreak analysis highlighted metabolic syndrome, hepatic steatosis, insulin resistance, hepatocellular carcinoma, cardiovascular disease, intestinal permeability, and intestinal bacterial overgrowth as prominent areas of intense research.
    CONCLUSION: Through the quantitative analysis of relevant literature, the current research focus and direction of gut microbiota and NAFLD can be more clearly understood, which helps us better understand the pathogenesis of NAFLD, and also opens up innovative solutions and strategies for the treatment of NAFLD.
    Keywords:  Bibliometric; Citespace; Gut microbiota; Knowledge maps; Nonalcoholic fatty liver disease; VOSviewer
    DOI:  https://doi.org/10.4254/wjh.v17.i1.102034
  38. Aesthet Surg J Open Forum. 2025 ;7 ojae123
    Bibliometric Analysis of the Highest Cited Cosmetic Upper Facial Plastic Surgery Articles Over 50 Years.
    Nitin Rangu, Evan Pistone, Jeremy Tan, Thai Do.
      In this bibliometric analysis, the authors analyze the top 100 (T100) most cited articles on cosmetic upper facial plastic surgery. Throughout this study, the objective of the authors is to delineate the trends in cosmetic upper facial surgeries to identify prevailing techniques, emerging trends, and potential areas of future investigation. The articles were indexed from the Web of Science database and were extracted in a double-blinded manner by 2 independent graders. The search phrase used covered a wide range of cosmetic upper facial plastic surgeries, of which a short sample is included: ("cosmetic*" AND "bleph*") OR ("cosmetic*" AND "upper eyelid blepharoplasty") OR ("cosmetic*" AND "lower eyelid blepharoplasty"). In their statistical analysis of the number of citations received in each article in the T100, the authors reveal an average of 55.1 citations (a standard deviation of 38.7). Surgical methods were the most commonly cited unique study area, with 30% of the T100, followed by botulinum toxin and complication management with 29% and 15% of the T100, respectively. The unique study area with the highest average citations received was botulinum toxin, with an average of 64.7 citations. Invasive procedures made up 55% of the T100 articles. The authors found that the late 1990s and 2000s were a burgeoning period of growth in this field and highlight the evolution of many contemporary popular cosmetic procedures over time. Particularly, a growth in minimally invasive procedures was noted, with noted impacts in aesthetics training and research focus.
    Level of Evidence 4 Therapeutic:
    DOI:  https://doi.org/10.1093/asjof/ojae123
  39. J Hand Microsurg. 2025 Mar;17(2): 100214
    Top 75 most-cited articles in hand microsurgery: A bibliometric and visualised analysis.
    Zhen Yu Wong, Oluwatobi Adegboye, Pegah Damavandi, Ryan Faderani, Muholan Kanapathy, Ben H Miranda, Dariush Nikkhah, Afshin Mosahebi.
       Introduction: Hand microsurgery is an important advancement of the speciality that has improved outcomes in hand trauma and hand surgical conditions. This bibliometric analysis aims to identify the 75 most cited hand microsurgery articles and explore their relevance to contemporary practice.
    Methods: The Web of Science core collection database was used to screen and identify the top 75 most-cited articles relevant to hand microsurgery. VOSviewer 1.6.18 and CiteSpace 6.2.R4 software were used to analyse and visualise occurrences, authorship, countries, institutions, journals, keywords, and Evidence Level (Oxford Centre for Evidence-Based Medicine).
    Results: The initial search identified 3024 articles. The top 75 most-cited articles were published between 1980 and 2018, with contributions from 291 authors. Professor Fu Chang Wei from Chang Gung Memorial Hospital, Taiwan, was the most prolific author. Articles originated from 14 countries, with the United States leading (29.3 %), followed by Taiwan (14.6 %), Italy (8.0 %), and Germany (8.0 %). The 75 most-cited articles were published in 22 journals, led by Plastic and Reconstructive Surgery, followed by the Journal of Hand Surgery (American Volume) and Microsurgery. A total of 345 keywords were analysed, with "Hand," "Defects," "Reconstruction," and "Regeneration" being the most frequent. Level of Evidence 4 was most common (40 %), followed by Levels 3 (25 %) and 5 (24 %).
    Conclusions: The top 75 most-cited hand microsurgery articles influence current surgical practice and teaching material. Understanding specific surgical techniques in hand microsurgery and examining their outcomes will benefit patients, surgeons, researchers and policymakers alike.
    Keywords:  Analysis; Bibliometric analysis; Defects; Digital amputation; Digital replantation; Hand microsurgery; Hand surgery; Microsurgery; Nerve injury; Replantation; Visual analysis
    DOI:  https://doi.org/10.1016/j.jham.2025.100214
  40. Int Ophthalmol. 2025 Jan 29. 45(1): 47
    Bibliometric analysis of published works in ocular trauma: a growing focus on open globe injury.
    Hassaam S Choudhry, Eric J Kuklinski, Allen Fu, Param Shukla, Matthew Montani, Fareeda Eraky, Marco A Zarbin, Paul D Langer, Neelakshi Bhagat.
       PURPOSE: The purpose of this study is to analyze the trends and characteristics of ocular trauma research published from 2000 to 2022 to delineate the trajectory of the field's research, provide information about the network of key contributors, and help determine future research strategies and direction.
    METHODS: Web of Science was queried for published works using a series of keywords relating to ocular trauma: "globe rupture", "ruptured globe", "globe injury", "ocular trauma", "intraocular foreign body", "eye trauma", "eye injury", and "traumatic endophthalmitis". All article information was compiled using the VOSviewer software. Article information analyzed included year of publication, publishing journal, author, institution, country, and keywords/key terms.
    RESULTS: A total of 3362 articles were identified. In the time period studied, there is a noticeable trend for an increase in the number of papers pertaining to ocular trauma to be published annually. The journal, Eye published the most, and the United States produced the most articles of any country. Important keywords other than "ocular trauma" included "epidemiology", "management", "children", "vitrectomy" and "endophthalmitis".
    CONCLUSION: Complications due to ocular trauma are seen worldwide. Many different institutions, journals, and countries have published research on ocular trauma with an increased frequency in recent years. This study provides valuable information on the status of scholarly investigation of ocular trauma in the last 2 decades and sheds light on the trajectory of recent research interest.
    Keywords:  Bibliometric analysis; Epidemiology; Ocular trauma; Open globe injury; Research trends
    DOI:  https://doi.org/10.1007/s10792-025-03417-5
  41. Front Microbiol. 2024 ;15 1455540
    Biological function of d-tryptophan: a bibliometric analysis and review.
    Fei Wang, Runyu Du, Yunxiao Shang.
       Background: d-Tryptophan is recognised for its unique physiological properties. In this study, we aimed to explore the dynamic trends and emerging topics in d-tryptophan research to offer fresh perspectives for future studies.
    Methods: Employing bibliometric analysis, we examined the literature on d-tryptophan indexed in the Web of Science Core Collection from January 1987 to December 2023. The "Bibliometrix" R package and CiteSpace were utilised for data processing.
    Results: Analyses of 865 publications revealed 2209 keywords, 4068 authors, 2094 institutions, and contributors from 302 regions. The USA was at the forefront of publications concerning d-tryptophan, but the European Journal of Pharmacology, Journal of Biological Chemistry, and Journal of Medicinal Chemistry were notable for their contributions, co-citations, and impact, respectively. This literature review reveals that since 1987, studies have developed from a focus on d-tryptophan metabolism to the exploration of its functions in organic and medicinal chemistry and food science. Recent findings highlight the potential of d-tryptophan as a non-nutritional sweetener and food preservative as well as its role in inhibiting the growth of bacterial biofilms. Additionally, its immunomodulatory properties are being investigated in relation to allergic diseases. Furthermore, d-tryptophan plays a role in the therapy of atherosclerosis, osteoporosis, tuberculosis, and cancer.
    Conclusion: The results of bibliometric analysis highlight that future research should focus on the biological functions of d-tryptophan as a food preservative and its use in immunomodulation and drug development, providing strong guidance for future research.
    Keywords:  bibliometric analysis; biological function; d-amino acids; d-tryptophan; literature review
    DOI:  https://doi.org/10.3389/fmicb.2024.1455540
  42. Materials (Basel). 2025 Jan 13. pii: 333. [Epub ahead of print]18(2):
    Vegetable Fibers in Cement Composites: A Bibliometric Analysis, Current Status, and Future Outlooks.
    A Arvizu-Montes, M J Martinez-Echevarria.
      The use of vegetable fibers (VFs) in cement-based composites has increased in recent years owing to their minimal environmental impact and notable particular properties. VFs have aroused interest within the scientific community because of their potential as a sustainable alternative for construction. This study presents a comprehensive bibliometric analysis of VFs in cement composites using data from the Scopus database and scientometric tools to explore publication trends, influential sources, and research directions. Key findings reveal a steady increase in publications, with Construction and Building Materials identified as a leading journal in the field and China and Brazil as prominent contributors in terms of publications and citations. The analysis highlights a strong focus on mechanical properties and durability, reflecting the interest of the scientific community in optimizing VF composites for construction. Furthermore, this study includes a revision of the most influential studies addressing VF classification, durability improvements, and advanced applications of VFs in building applications. Finally, future research opportunities are outlined, emphasizing Life Cycle Assessment (LCA), industry integration, CO2 absorption, and the application of machine learning techniques to advance the development of VF composites. This work provides a comprehensive overview of the field, suggesting future guidelines and promoting collaborative research.
    Keywords:  cement composites; durability; mechanical properties; scientometric analysis; vegetable fibers
    DOI:  https://doi.org/10.3390/ma18020333
  43. Int J Surg. 2025 Jan 24.
    Exploring the landscape of exosomes in heart failure: a bibliometric analysis.
    Hui Li, Zhitao Li, Qinghui Fu, Shuiqiao Fu, Tao Xiang.
       BACKGROUND: Exosomes, which carry bioactive RNAs, proteins, lipids, and metabolites, have emerged as novel diagnostic markers and therapeutic agents for heart failure (HF). This study aims to elucidate the trends, key contributors, and research hotspots of exosomes in HF.
    METHODS: We collected publications related to exosomes in HF from the Web of Science Core Collection. Using VOSviewer, CiteSpace, Excel, and SRplot software, we performed a visualization analysis of authors, countries, institutions, keywords, and references.
    RESULTS: The publications on exosomes in the field of HF (N = 2127) has grown rapidly. China (N = 245, 42.683%) and the United States (N = 170, 29.617%) are the leading contributors in this area. Wang L (N = 14, 2.443%) is the most prolific author in the field. Key areas of exosome research in HF include mesenchymal stem cells (MSCs), angiogenesis, and microRNAs. Additionally, keywords and references analysis reveal that exosome research in HF is primarily focused on the role of exosomes in intercellular communication in HF, the value of miRNAs in exosomes as diagnostic markers, and the therapeutic mechanisms of MSC-derived exosomes.
    CONCLUSION: Exosomes are receiving increasing attention in the field of HF. Mapping the development landscape of exosomes in HF will help researchers accelerate progress in this area.
    DOI:  https://doi.org/10.1097/JS9.0000000000002248
  44. Cureus. 2024 Dec;16(12): e76510
    Exploring the Research Landscape of Transcranial Direct Current Stimulation in Stroke: A Bibliometric Review.
    Ayesha Juhi, Rintu Kumar Gayen, Manul Das, Chanchal Goyal, Shreya Sharma, Md Asif Khan, Pritam Chaudhary, Himel Mondal.
      Transcranial direct current stimulation (tDCS) has gained significant attention as a potential therapeutic tool in stroke rehabilitation, promoting neuroplasticity and enhancing motor and cognitive recovery. Despite growing research, the field's evolution and key trends remain underexplored. This study aims to perform a bibliographic analysis of publications related to tDCS and stroke rehabilitation to assess the growth of the field. Published literature was searched in PubMed and Web of Science (WOS) on 10 December 2024. We used the keywords "transcranial direct current stimulation" and "stroke" to collect studies without any time limitation. Articles found in WOS were used to get trends, and a search from PubMed was used to analyze co-occurrences in VOSviewer, version 1.6.20 (Centre for Science and Technology Studies, Leiden University, the Netherlands). A total of 1,598 articles were found in WOS, and 1,300 were found in PubMed. As there was overlapping of subject categories, countries, and affiliations, the total number differed in calculating the percentages. The analysis revealed significant growth in publications on tDCS and stroke rehabilitation, peaking at 137 publications in 2022. Most studies focus on neuroscience (860, or 30.6%), clinical neurology (562, or 20%), and rehabilitation (244, or 8.68%). The United States leads contributions (519, or 22.4%), followed by Germany (249, or 10.7%) and China (179, or 7.7%). Publications are concentrated among major publishers like Elsevier (358, or 22.4%) and key journals such as Brain Stimulation and Frontiers in Human Neuroscience. English dominates as the primary language (1,572, or 98.37%). Research emphasizes tDCS's role in motor recovery and brain plasticity in stroke rehabilitation. This bibliometric analysis highlights a substantial and growing interest in tDCS for stroke rehabilitation, with a steady increase in publications. The focus of research predominantly lies in neuroscience, clinical neurology, and rehabilitation, reflecting the central role of tDCS in advancing stroke recovery and brain plasticity. The concentration of publications among major publishers and journals underscores the prominence of specific platforms in disseminating tDCS research. More research from developing countries is needed to achieve a balanced geographical diversity on this topic.
    Keywords:  bibliometric analysis; citation analysis; cognitive recovery; motor recovery; neuroplasticity; research trends; stroke rehabilitation; stroke therapy; tdcs; transcranial direct current stimulation
    DOI:  https://doi.org/10.7759/cureus.76510
  45. Hum Vaccin Immunother. 2025 Dec;21(1): 2457189
    Global research hotspots and trends in DNA vaccine research: A bibliometric and visualization study from 2014 to 2024.
    Juan Zhang, Haiguo Zhang, Cuicui Yao, Lihua Gu, Shasha Dong, Yamei Wu, Lele Miao.
      This bibliometric and visualization study provides a comprehensive analysis of global research hotspots and trends in DNA vaccine research from 2014 to 2024. By employing data sourced from the Web of Science Core Collection, we identified a total of 3,600 articles. Our analysis reveals a declining trend in annual publications. Active countries, institutions, journals, and authors were identified, with China, the Pasteur Network, the Vaccine Journal, and David B Weiner being the most prolific contributors. Keywords cluster analysis distinguished four major research directions: infectious disease and immunity, viral challenge and vaccine development, optimization of DNA vaccine delivery systems, and cancer and immunotherapy research. The literature co-citation analysis revealed four major research hotspots, including DNA vaccines for Zika virus, human papillomavirus (HPV), and COVID-19, as well as safety, efficacy, and immunogenicity studies of DNA vaccines. Concurrently, the burst citation analysis identified emerging themes, including the development of DNA vaccines for COVID-19, Ebola, and MERS-CoV, as well as innovations in antigen design and delivery technologies. This study offers valuable insights into the evolution and future directions of DNA vaccine research, emphasizing its importance for global public health and the potential to address current and future health challenges.
    Keywords:  DNA vaccine; bibliometric; emerging topics; hotspots; visualization
    DOI:  https://doi.org/10.1080/21645515.2025.2457189
  46. Photodiagnosis Photodyn Ther. 2025 Jan 22. pii: S1572-1000(25)00024-9. [Epub ahead of print] 104494
    Bibliometric analysis of photodynamic research in bladder cancer: trends and future directions.
    Xi Xu, Jinshan Xu, Hongliang Gao, Zhaoyang Sheng, Yang Xu, Shuxiong Zeng, Guanghua Chen, Zhensheng Zhang.
       BACKGROUND: Recent years have seen the use of photodynamic technologies concerning the detection and therapy of bladder cancer (BC) due to their rapid development and well-established therapeutic impact. However, a thorough analysis and bibliometric assessment of photodynamic technologies publishing trends in BC has not been completed yet.
    METHODS: Retrieving bibliographies from the Web of Science Core Collection limited the publication date to December 31, 2023, from January 1, 2004. We used VOSviewer (Version 1.6.19) and CiteSpace (Version 6.4 R1) for both statistical and visualization analysis.
    RESULTS: We selected a total of 870 documents for analysis. The yearly publication findings show notable upward patterns over the last two decades. The Kochi Medical School in Japan was the most productive school, while the USA was the most productive nation. Japanese researcher Inoue Keiji published the highest number of photodynamic -related articles in BC. The most quoted and prolific journals were the Photodynamic Therapy and Photodiagnosis. According to the keyword analysis, the terms "cystoscopy," "carcinoma in situ," "drug delivery," "follow-up," "hexaminolevulinate," and "impact" are all relatively recent and hot field.
    CONCLUSIONS: Our investigation produced a bibliometric outcome for the field, potentially opening up new research opportunities. We suggest that future research concentrate on in-situ carcinoma identification, photosensitizer invention, medication delivery enhancement, and photodynamic technology follow-up in BC.
    Keywords:  Bibliometric; Bladder cancer; Cystoscopy; Diagnosis; Drug delivery; Photodynamic technology
    DOI:  https://doi.org/10.1016/j.pdpdt.2025.104494
  47. Front Oncol. 2024 ;14 1487198
    Seeing beyond words: nanotechnology in hepatocellular carcinoma - a bibliometric study.
    Talaiti Tuergan, Aimitaji Abulaiti, Alimu Tulahong, Ruiqing Zhang, Zhongdian Yuan, Yanze Lin, Yingmei Shao, Tuerganaili Aji.
       Background: Nanotechnology has increasingly been applied in the diagnosis and treatment of hepatocellular carcinoma (HCC) over the past two decades. This study aims to explore the utilization of nanotechnology in HCC through a bibliometric analysis, identifying key themes, trends, and contributions in this field.
    Methods: The study utilized VOSviewer and CiteSpace software to perform a bibliometric analysis, evaluating scholarly contributions related to nanotechnology in HCC. The analysis focused on co-occurrence network relationships, publications, citations, and contributions from various entities and authors.
    Results: The analysis revealed a total of 2,968 articles, with China and the USA being the most prominent contributors in terms of publications and citations. Notable contributions were made by the Chinese Academy of Sciences and authors Gao Jie and Li Yan. LLOVET JM emerged as the most co-cited author, indicating a leadership role in the field. The "International Journal of Nanomedicine" was identified as the leading publisher, while "Biomaterials" ranked highest in citations. The research mainly focused on drug delivery systems and apoptosis, highlighting significant advancements in utilizing nanotechnology for HCC treatment.
    Conclusion: This bibliometric study underscores the critical role of nanotechnology in advancing the diagnosis and treatment of hepatocellular carcinoma, with a particular emphasis on drug delivery and apoptosis. The findings highlight the contributions of key countries, institutions, and authors, reflecting the global effort and collaboration in this rapidly evolving field.
    Keywords:  apoptosis; bibliometrics; drug delivery; hepatocellular carcinoma; nanotechnology
    DOI:  https://doi.org/10.3389/fonc.2024.1487198
  48. Psychol Health Med. 2025 Jan 31. 1-17
    The top 100 cited papers on mental health and virtual reality: a bibliometric analysis.
    Yimin Guan, Yaqing Wang, Dongmei Zhuang, Wenzhuo Wei, Lijun Ma, He Du, Chuan Fan, Xiaoming Li.
      Virtual reality technology has been widely applied in the field of mental health research. However, to date, no study has employed bibliometric methods to systematically analyze the application of virtual reality in mental health. By searching the Web of Science Core Collection, we have summarized the top 100 cited papers in this field and conducted the first bibliometric study on mental health and virtual reality using CiteSpace. The results indicate that this area has received considerable attention. The United States stands out as the most influential country. The University of London and Emory University are the leading contributing institutions. Rothbaum BO is the most productive author, and Cyberpsychology, Behavior, And Social Networking, is the journal with the most publications in this area. The primary focus of research in this domain is on virtual reality therapy for mental disorders, especially virtual reality exposure therapy for anxiety disorders. These findings may help researchers understand the current state and future trends in the field of mental health and virtual reality.
    Keywords:  Mental health; bibliometric analysis; virtual reality
    DOI:  https://doi.org/10.1080/13548506.2025.2460336
  49. Front Med (Lausanne). 2024 ;11 1487981
    A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases.
    Fushen Zhang, Weiye Xu, Zejun Deng, Jufang Huang.
      Electrochemical biosensors can provide an economical, accurate and rapid method for early screening of disease biomarkers in clinical medicine due to their high sensitivity, selectivity, portability, low cost and easy manufacturing, and multiplexing capability. Tear, a fluid naturally secreted by the human body, is not only easily accessible but also contains a great deal of biological information. However, no bibliometric studies focus on applying electrochemical sensors in tear/eye diseases. Therefore, we utilized VOSviewer and CiteSpace, to perform a detailed bibliometric analysis of 114 papers in the field of research on the application of tear in electrochemical biosensors screened from Web of Science with the combination of Scimago Graphica and Microsoft Excel for visualization to show the current research hotspots and future trends. The results show that the research in this field started in 2008 and experienced an emerging period in recent years. Researchers from China and the United States mainly contributed to the thriving research areas, with 41 and 29 articles published, respectively. Joseph Wang from the University of California San Diego is the most influential author in the field, and Biosensors & Bioelectronics is the journal with the most published research and the most cited journal. The highest appearance keywords were "biosensor" and "tear glucose," while the most recent booming keywords "diagnosis" and "in-vivo" were. In conclusion, this study elucidates current trends, hotspots, and emerging frontiers, and provides future biomarkers of ocular and systemic diseases by electrochemical sensors in tear with new ideas and opinions.
    Keywords:  Bibliometrics; CiteSpace; VOSviewer; electrochemical biosensors; eye diseases; tears
    DOI:  https://doi.org/10.3389/fmed.2024.1487981
  50. Front Microbiol. 2024 ;15 1509749
    A bibliometric and visualized analysis of heartland virus.
    Huiying Zhang, Leiliang Zhang.
       Background: Heartland virus (HRTV) is an emerging tick-borne bunyavirus first detected in 2009. The purpose of this study was to utilize bibliometric analysis to assess the research trends, key foci, and progress of HRTV. This analysis aims to provide valuable references and insights for future basic research and prevention and control of HRTV to promote the progress and development of related fields.
    Methods: The Web of Science Core Collection (WOSCC) was used to extract global publications on the HRTV from 2013 to 2024. VOSviewer, CiteSpace, Scimago Graphica, and Bibliometrix were used to process the data and visualize the results.
    Results: A stable trend in publication numbers was observed, with 82 articles from 17 countries. The United States led in publications, with significant contributions from the Centers for Disease Control and Prevention-USA. Keywords indicated research emphasis on "Heartland virus" and "severe fever."
    Conclusion: HRTV research is in a phase of continuous and progressive growth, with a steady literature output over the past decade, indicating this field's wide interest and importance in the research community. Currently, researchers are focusing on pathogenesis, immune response, vector relationships, and epidemiology, providing valuable insights for future studies.
    Keywords:  CiteSpace; HRTV; VOSviewer; bibliometric; heartland virus
    DOI:  https://doi.org/10.3389/fmicb.2024.1509749
  51. Diabetes Metab Syndr. 2025 Jan 16. pii: S1871-4021(25)00007-4. [Epub ahead of print]19(2): 103190
    Letter to the Editor regarding "Global research trends and hotspots in gestational diabetes and long-term cardiovascular health: A bibliometric analysis."
    Hao-Han Rao, Feng Guo, Jie Tian.
      
    Keywords:  Bibliometric analysis; Cardiovascular health; Gestational diabetes; Search strategy
    DOI:  https://doi.org/10.1016/j.dsx.2025.103190
  52. J Multidiscip Healthc. 2025 ;18 339-353
    Community Integration of Disability: A Bibliometric and Knowledge-Map Analysis.
    Shuaiyou Wang, Dingding Li, Chenjun Liu, Xueting Sun, Yage Shi, Hongru Wang, Huimin Zhang.
       Background: Community integration (CI) is the ultimate goal of rehabilitation for individuals with disabilities. It plays a significant role in restoring their social functioning and facilitating their reintegration into community and family life. However, no studies have utilized bibliometric methods to explore community integration.
    Objective: To conduct a review about community integration of disabilities and to clarify the knowledge, hotspots, and trends through the bibliometric method.
    Methods: Studies on community integration from 1990 to 2023 were retrieved from the Web of Science Core Collection (WOSCC). CiteSpace 6.2.R4 and Microsoft Office Excel 2019 were applied. The CiteSpace node types involved in this study include keyword, reference, cited author, cited Journal, and the dual-map overlay of journals. CiteSpace presented the keyword cluster map, keywords timeline view map, keywords bursts map, and overlay map of journals. Microsoft Office Excel 2019 was used to present the trend of annual publications and draw up related tables and figures.
    Results: A total of 2239 hits were included. The number of publications related to community integration is increasing gradually. The three most frequent keywords is Brain Injury (571, 13%), Individuals (488, 11%), Quality of Life (434, 10%). Keyword cluster map and timeline map with eight clusters were obtained, and the current strongest citation burst keywords are social participation, substance use, experiences, interventions, and Afghanistan. Willer is the author with the most citations. McColl has the largest centrality in the first ten cited authors. The most cited reference is published by the World Health Organization (WHO). Archives of Physical Medicine and Rehabilitation is the journal with the highest co-citation frequency. The overlay map of journals presented four distinct paths: the journals in "psychology education, health" and "neurology, sports, ophthalmology" often cite journals in "health, nursing, medicine" and "psychology, education, social".
    Conclusion: Community integration for individuals with disabilities is gradually becoming a hot topic. Research on community integration related to traumatic brain injury (TBI), stroke, children, and spinal cord injuries is current focus of community integration. Future research should explore the experiences and feelings of different groups of disabilities regarding community integration and develop more effective interventions for their community integration. Community integration is complex, and future research on community integration for individuals with disabilities needs to be explored more specifically.
    Keywords:  CiteSpace; bibliometric; community integration; community reintegration; disability; quality of life; rehabilitation
    DOI:  https://doi.org/10.2147/JMDH.S494130
  53. Am Psychol. 2025 Jan 30.
    Registered reports in psychology across scholarly citations and public dissemination: A comparative metaevaluation of more than a decade of practice.
    Zheng Liu, X T XiaoTian Wang, Zhonghan Wang, Weijin Yan, Mengzhen Hu.
      After more than a decade of practice, registered reports (RRs) are widely adopted in psychology. However, the acceptance of RRs in terms of postpublication academic recognition and public dissemination, compared with nonregistered reports (non-RR), remained largely unexplored. This matched meta-evaluation identified and analyzed 119 pairs of original research articles (RR vs. non-RR) from 33 psychology journals, matched for the journal of publication, time of publication, and research topic. The exploratory results show that RRs significantly reduced publication bias against null results and improved method and data transparency. However, RRs had lower citation counts than non-RRs, with a small effect size when controlling for days since publication. Additional exploratory analyses found that this effect remained significant after controlling for null-result reporting, transparency, the number of studies in an article and length of method and result sections, article title perception, open access, and authorship metrics (including the number of authors, the h-index of the first or corresponding authors). The overall public impact indexed by Altmetric attention scores and the number of Twitter posts were not significantly different between RRs and non-RRs. However, Twitter posts, but not citations and Altmetric attention scores, were moderated by journal reputation, with RRs receiving more attention in lower impact journals (5-year impact factor below 4.5). These exploratory findings help generate testable hypotheses about the potential differential effects of RRs on academic recognition and public attention, informing future directions for open science practice. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
    DOI:  https://doi.org/10.1037/amp0001503
  54. J Hand Surg Eur Vol. 2025 Jan 25. 17531934241313205
    The 100 most-cited articles in WALANT hand surgery: A bibliometric and visualized analysis.
    Zhen Yu Wong, Oluwatobi Adegboye, Muholan Kanapathy, Dariush Nikkhah, Afshin Mosahebi, Ben H Miranda.
      This bibliometric analysis aimed to define important topics and developments across wide awake local anaesthesia no tourniquet (WALANT) hand surgery, an innovative ambulatory technique that gained popularity during the COVID-19 pandemic. Articles were searched and screened using the Web of Science core collection database. VOSviewer 1.6.18 and bibliometrix were used for analysis. In the initial search 419 articles were found. Between 1990 and 2023, 333 writers contributed to the top 100 most-cited articles published. The country with the highest number of published articles (20%) was Canada, followed by the USA (18%) and China (12%). Most articles were published in Plastic and Reconstructive Surgery (15%), Hand Clinics (14%) and the European and American volumes of The Journal of Hand Surgery (9% each). Eighty-two percent of articles had a Level of Evidence of III or V. High-quality randomized controlled trials and systematic reviews of WALANT are needed to broaden and enhance clinical practice and research.Level of evidence: V.
    Keywords:  WALANT; bibliometric; hand surgery; tourniquet; visualisation; wide awake local anaesthesia no tourniquet
    DOI:  https://doi.org/10.1177/17531934241313205
  55. Front Med (Lausanne). 2024 ;11 1505692
    Evolution of artificial intelligence in healthcare: a 30-year bibliometric study.
    Yaojue Xie, Yuansheng Zhai, Guihua Lu.
       Introduction: In recent years, the development of artificial intelligence (AI) technologies, including machine learning, deep learning, and large language models, has significantly supported clinical work. Concurrently, the integration of artificial intelligence with the medical field has garnered increasing attention from medical experts. This study undertakes a dynamic and longitudinal bibliometric analysis of AI publications within the healthcare sector over the past three decades to investigate the current status and trends of the fusion between medicine and artificial intelligence.
    Methods: Following a search on the Web of Science, researchers retrieved all reviews and original articles concerning artificial intelligence in healthcare published between January 1993 and December 2023. The analysis employed Bibliometrix, Biblioshiny, and Microsoft Excel, incorporating the bibliometrix R package for data mining and analysis, and visualized the observed trends in bibliometrics.
    Results: A total of 22,950 documents were collected in this study. From 1993 to 2023, there was a discernible upward trajectory in scientific output within bibliometrics. The United States and China emerged as primary contributors to medical artificial intelligence research, with Harvard University leading in publication volume among institutions. Notably, the rapid expansion of emerging topics such as COVID-19 and new drug discovery in recent years is noteworthy. Furthermore, the top five most cited papers in 2023 were all pertinent to the theme of ChatGPT.
    Conclusion: This study reveals a sustained explosive growth trend in AI technologies within the healthcare sector in recent years, with increasingly profound applications in medicine. Additionally, medical artificial intelligence research is dynamically evolving with the advent of new technologies. Moving forward, concerted efforts to bolster international collaboration and enhance comprehension and utilization of AI technologies are imperative for fostering novel innovations in healthcare.
    Keywords:  ChatGPT; artificial intelligence; bibliometric study; health care; medicine
    DOI:  https://doi.org/10.3389/fmed.2024.1505692
  56. Front Sociol. 2024 ;9 1461840
    Scientific mapping of the nexus between entrepreneurial orientation and environmental sustainability: bibliometric analysis.
    Tadesse Weyuma Bulto, Abdella Kosa Chebo, Hailu Fufa Regassa, Birhanu Chalchisa Werku, Helmut Kloos.
      Entrepreneurial orientation (EO) and environmental sustainability (ES) has recently become the subject of extensive research. The objective of this paper is to comprehensively analyze of EO and ES by conducting a bibliometric network and systematic review analysis of over ten years of publications. A total of 390 articles were identified using the Scopus and Mendeley search engines. One hundred-eighteen articles published in 53 journals between 2012 and 2021 were identified for analysis. Association analysis was conducted by author, co-author, and keyword, as well as keyword analysis by title and abstract fields, abstract field, and title field words with the highest frequency and highest relevance score under the binary counting approach. Performance, entrepreneurial orientation, relationship, entrepreneurship, entrepreneur, and business keywords were the most dominant occurrences in the abstracts. Key topics included models for entrepreneurial orientation; environmental sustainability was potentially more comprehensive in understanding the review work. This comprehensive review holds substantial theoretical significance for advancing the agenda of ecological entrepreneurial orientation and environmental sustainability. The findings of the study will help academics and researchers to identify future research directions and subject areas.
    Keywords:  Scopus; bibliometric analyses; entrepreneur; entrepreneurial orientation; environmental sustainability
    DOI:  https://doi.org/10.3389/fsoc.2024.1461840
  57. Foods. 2025 Jan 14. pii: 251. [Epub ahead of print]14(2):
    A Review on Blockchain Applications in Operational Technology for Food and Agriculture Critical Infrastructure.
    Chengliang Zheng, Xiangzhen Peng, Ziyue Wang, Tianyu Ma, Jiajia Lu, Leiyang Chen, Liang Dong, Long Wang, Xiaohui Cui, Zhidong Shen.
      The food and agriculture sector is a cornerstone of critical infrastructure (CI), underpinning global food security, public health, and economic stability. However, the increasing digitalization and connectivity of operational technologies (OTs) in this sector expose it to significant cybersecurity risks. Blockchain technology (BT) has emerged as a transformative solution for addressing these challenges by enhancing network security, traceability, and system resilience. This study presents a comprehensive review of BT applications in OT security for food and agriculture CI, employing bibliometric and content analysis methods. A total of 124 relevant articles were identified from six databases, including the Web of Science Core Collection and MEDLINE®. Bibliometric analysis was conducted across five dimensions: publication year, literature type, journal distribution, country contributions, and keyword trends. The findings are meticulously organized through tables, charts, and graphs. The year 2018 marked a surge in research within this domain, with the IEEE Internet of Things Journal and IEEE ACESS emerging as the most prolific journals, each boasting nine publications. The United States, China, and India are at the forefront in terms of journal citation counts. Our analysis determined that a reference count of 37 serves as an appropriate threshold. Otoum Safa stands out as the author with the highest number of published articles, totaling four. Keywords such as "blockchain", "internet of things", "smart contract", "security", and "critical infrastructure" appear with significant frequency. The statistics, trends, and insights gleaned from this bibliometric analysis can guide researchers in the OTCI field to forge a coherent and logical research trajectory. Content analysis further identified six key research areas within this domain: identity authentication and data verification, secure access control, attack detection and perception, data security and protection, data backup and recovery, and attack assessment and attribution. Based on these insights, a general framework is proposed to guide future research and practical applications of BT in securing OT within food and agriculture CI. This study systematically analyzes the current research landscape, challenges, and opportunities for BT in securing the OT critical to food and agriculture CI. By bridging the gap between blockchain innovations and the operational needs of the food and agriculture sector, this work contributes to advancing strategic implementation and improving the security of CI systems.
    Keywords:  bibliometric analysis; blockchain technology; critical infrastructure; cybersecurity; food and agriculture
    DOI:  https://doi.org/10.3390/foods14020251
  58. Curr Probl Diagn Radiol. 2025 Jan 27. pii: S0363-0188(25)00009-X. [Epub ahead of print]
    A retrospective analysis of medical student authorship in highest impact radiology journal publications.
    Aiman Shahid, Rooshi Parikh, Muhammad Ebrahim Shahid, Aleena Malik, Sonali Sharma, Faisal Khosa.
       OBJECTIVES: To assess medical student authorship in radiology research, focusing on the prevalence and impact of student articles, demographic trends, and potential barriers and opportunities for involvement.
    METHODS: We retrospectively assessed original research and review papers from 2018 to 2022 in the top five radiology journals based on their 2022 Impact Factor. Three reviewers manually validated and classified articles by medical student (MS) and non-MS authorship. Data collected included publication and authorship metrics. Thematic analysis of articles was performed from keywords and SCOPUS topic clusters. Significant associations were identified using chi-squared and two-tailed z-tests.
    RESULTS: Of the 2533 publications from all five journals, only 0.47 % were MS-authored, of which 83.3 % had a Field Weighted Citation Impact (FWCI) > 1. Of the 19 MS authors, 68.42 % had prior publications, with the same proportion holding prior first authorship. Female students averaged a higher FWCI (2.47 ± 2.31) but comprised only 26.32 % of all students. Only 16.67 % of MS articles had a female senior author (SA). This was consistent in non-MS articles, with females representing 19.9 % to 25.2 % of SAs across all journals. Of the 2521 non-MS articles, 92 % were classified into themes, revealing that 47.89 % of publications primarily focused on machine learning, while another 42.26 % incorporated some machine learning concepts.
    CONCLUSION: Compared to non-medical student publications in radiology, those by medical students were disproportionately limited but impactful. Both demographic and academic factors hinder student engagement in publishing. Hence promoting, supporting, and sponsoring student involvement in research is pivotal for the discipline.
    Keywords:  Artificial Intelligence; Authorship; Demographics; Journal Impact Factor; Medical Student
    DOI:  https://doi.org/10.1067/j.cpradiol.2025.01.007
  59. J Clin Orthop Trauma. 2025 Mar;62 102882
    Trends in shoulder arthroplasty research over the decades.
    Leanne Dupley, Yousif Atwan, Aparna Viswanath.
       Introduction: The aim of this study is to analyse the most cited articles in shoulder arthroplasty surgery and identify trends in topics by decade.
    Methods: Journal Citation Index Web of Science (WoS) was searched to find articles using the search terms "shoulder arthroplasty", "shoulder hemiarthroplasty", "shoulder replacement" and "shoulder prosthesis". All articles were ranked according to most cited overall and most cited between 2022 and 2023, and then further analysed to find the most cited articles per decade. Articles were studies for topic, study type, evidence level and number of subjects. A second search was performed using Google Scholar (GS) with the same search terms.
    Results: All the most cited articles were published in 4 orthopaedic journals. Citation counts were higher for GS searches than WoS for every article, by an average of 1.92 times. Each decade's most cited articles seemed to fit into a few broad topics, showing trends in that decade. The highest cited papers were generally low-level evidence studies.
    Conclusion: Shoulder arthroplasty literature appears to follow trends throughout the decade. High quality evidence is lacking in the highest cited papers, but this study highlights the importance and value of these lower-evidence breakthrough studies, which have shaped shoulder arthroplasty surgery.
    Keywords:  Most cited; Shoulder arthroplasty; Shoulder hemiarthroplasty; Shoulder replacement; Shoulder trends
    DOI:  https://doi.org/10.1016/j.jcot.2024.102882
  60. Plast Surg (Oakv). 2025 Feb;33(1): 186-192
    An Investigation of Gender Representation and Collaboration in Academic Plastic Surgery Research.
    Sahil Chawla, Janani Rajendra, Thanansayan Dhivagaran, Jeffrey Ding, Kathryn V Isaac, Faisal Khosa.
      Background: Gender disparities in academic leadership positions may be influenced by several factors, including research productivity. We aimed to describe the publication gender gap in major plastic surgery journals, assess gender-related and gender-neutral research publications, and identify any potential gender disparities associated with publication characteristics. Methods: For this cross-sectional study, we reviewed all original research publications in Plastic and Reconstructive Surgery, JAMA Facial Plastic Surgery, and Aesthetic Surgery Journal from 2014 through 2018. Genderize.io was used to identify the gender of all authors. Each publication was classified as either gender-neutral, transgender health, women's health, or men's health-related based on the article's content. Results: Of the 12,718 authors across 2234 publications analysed, females were first authors in 30%, last authors in 17%, and all authors in 27%. Among the publications, 1782 (79.8%) were focused on gender-neutral, 419 (18.8%) on women's health, 18 (0.8%) on transgender health, and 15 (0.7%) on men's health. Male first authors were more likely to be associated with women's and transgender health articles (OR [95% CI]  =  1.4 [1.1-1.8] and OR [95% CI]  =  51.0 [47-55], p < .001) and had a higher mean number of citations compared to gender-neutral articles (p < .001). Male first authors were more likely to be associated with women's and transgender health articles (OR [95% CI]  =  1.4 [1.1-1.8] and OR [95% CI]  =  51.0 [47-55], p < .001) and had a higher mean number of citations compared to gender-neutral articles (p < .001). Conclusion: The publication gender gap persists in academic plastic surgery. The academic community should continue to prioritize addressing gender disparity from the perspective of research productivity.
    Keywords:  author gender; authorship; gender disparities; plastic surgery; publication
    DOI:  https://doi.org/10.1177/22925503231190928
  61. Radiography (Lond). 2025 Jan 29. pii: S1078-8174(25)00018-5. [Epub ahead of print]
    An overview of radiography research and publication productivity in Denmark.
    J Jensen, P B Andersen, F Skjøth, M R V Pedersen.
       OBJECTIVES: This paper presents the progress of publications with Danish radiographers in scientific journals. The objective was to gain an overview of research in radiography in Denmark by exploring how publications with radiographer involvement have evolved over time in Denmark. We conducted a literature search on February 20th 2024 to identify papers authored or co-authored by Danish radiographers over the past thirteen years. The papers were screened by two authors (JJ & MRVP) using the online tool Covidence. All identified authors affiliated to a Danish Department of Radiology were searched in the Danish healthcare authorization register. Articles with authors, who were registered as a radiographer, were included in the study. Information on publication year, title, journal, and impact factor, citations, and nationality of co-authors were extracted.
    KEY FINDINGS: In total, 243 paper who had one or more Danish radiographers affiliated as an author were included encompassing 97 different Danish radiographers. The majority of the radiographers, 89, had published between 1 and 10 articles and the remainder 8 authors between 11 and 43 publications. We observed an increase in publications over time, indicating an increasing interest for involvement in research.
    CONCLUSION: We found that the number of peer-review publications with involvement of at least one radiographer has increased markedly during the last decade although the majority of the publications were made by a small group of radiographers. The radiography research in Denmark is wide-ranging and provides impact within and outside radiology journals.
    IMPLICATION FOR PRACTICE: The study demonstrates that professional development is on the rise in Denmark. However, it also underscores the need for a continued focus on the sustainability of radiographer-led research, as the majority of publications come from the contributions of eight radiographers.
    Keywords:  Advanced practice; Career path; Radiography; Research
    DOI:  https://doi.org/10.1016/j.radi.2025.01.012
  62. Turk J Emerg Med. 2025 Jan-Mar;25(1):25(1): 41-46
    Publication rates and features of abstracts presented at emergency medicine congresses in Türkiye: An analysis of 10,055 abstracts.
    Sinan Karacabey, Erkman Sanrı, Emre Kudu, Emir Ünal, Melis Efeoğlu Saçak, Mehmet Birkan Korgan.
       OBJECTIVES: The domain of emergency medicine (EM) is not only rapidly evolving but also witnessing a significant surge in research publications, particularly in Türkiye. In this context, this study aimed to investigate the publication outcomes of abstracts presented at national EM conferences and evaluate the quality of these publications, thereby contributing to the understanding of the evolving landscape of EM research in Türkiye.
    METHODS: To ensure the accuracy and reliability of our findings, we meticulously examined abstracts presented at the annual conferences organized by the EM Association of Türkiye and Emergency Physicians Association of Türkiye from January 2015 to December 2021. We screened public databases such as Web of Science, SCOPUS, PubMed, Google Scholar, and ULAKBIM to identify any subsequent publications of these abstracts. The data on publication dates, and journal impact factors were thoroughly analyzed.
    RESULTS: The study included 10,055 abstracts, comprising 3794 (37.7%) oral presentations and 6261 (62.3%) poster presentations. Of these, 829 abstracts (8.2%) were later published as full publications in journals indexed in at least one major database. Among the published articles, 36 (4.3%) appeared in Q1 journals, while 346 (41.6%) were published in journals without quartile rankings. The median duration until publication was observed to be 12 months.
    CONCLUSION: The publication rate for abstracts presented at EM conferences was 8%, with most articles published within 2 years. Oral presentations had a higher publication rate than poster presentations, indicating higher quality. The authors' affiliations and the studies' designs emerged as pivotal factors influencing the success of publication.
    Keywords:  Abstracts; bibliometrics; congress; emergency medicine; publications; research
    DOI:  https://doi.org/10.4103/tjem.tjem_90_24
  63. Perspect Clin Res. 2025 Jan-Mar;16(1):16(1): 54-55
    Lack of transparency for Investigators in clinical trials: A bibliometric analysis of literature.
    Rohit Prasad.
      
    DOI:  https://doi.org/10.4103/picr.picr_12_24
  64. World J Gastroenterol. 2025 Jan 28. 31(4): 100718
    Advances in gastrointestinal vascular bleeding disorders: Successful sirolimus treatment in colonic angioectasia.
    Qi Sun, Xiao-Ying Wang, Dong-Hao Li, Bai-Rong Li, Xin-Zhuo Tu, Zhi-Meng Jiang, Shou-Bin Ning, Tao Sun.
       BACKGROUND: Gastrointestinal (GI) vascular bleeding disorders pose significant clinical challenges due to their complex pathogenesis and varied treatment responses. Despite advancements in diagnostic and therapeutic techniques, optimal management strategies remain elusive, necessitating further research.
    AIM: To assess research trends and clinical advancements in GI vascular bleeding disorders, highlighting key themes and therapeutic progress.
    METHODS: A bibliometric analysis was conducted using the Web of Science Core Collection database, reviewing publications from 2000 to 2024 to identify trends, high-frequency keywords, and key contributions from leading research institutions. In addition, a case study highlighted the effective application of sirolimus in managing colonic angioectasia in a patient with recurrent GI bleeding who had not responded to previous treatments.
    RESULTS: The analysis reviewed 470 scholarly articles from 203 countries, involving 2817 authors across 1502 institutions. The United States led in publication contributions, with strong collaborations with countries like China, England, and Germany. A significant trend was observed in the shift from traditional endoscopic interventions to pharmacological therapies, particularly highlighting the successful use of sirolimus in treating colonic angioectasia. High-frequency keywords such as "angiodysplasia", "colon", and "management" were identified, indicating key research themes. The study also noted a growing interest in drug therapies, as evidenced by the increasing prominence of keywords like "thalidomide" since 2018.
    CONCLUSION: This study links bibliometric analysis and clinical insights, highlighting the shift to pharmacological management in GI vascular bleeding disorders to improve patient outcomes.
    Keywords:  Angioectasia; Gastrointestinal bleeding; Pharmacological; Sirolimus; Vascular anomalies
    DOI:  https://doi.org/10.3748/wjg.v31.i4.100718
  65. Am J Ther. 2025 Jan 28.
    Oncolytic Virotherapy in Otorhinolaryngologic Neoplasms: A Scoping Review and Bibliometric Analysis.
    Amin Sharifan.
      
    DOI:  https://doi.org/10.1097/MJT.0000000000001876
  66. Shoulder Elbow. 2025 Jan 24. 17585732241310513
    Gender influence on career trajectory as a shoulder and elbow surgeon.
    Christopher W Haff, Justin T Childers, Jessica M Forbes, Benjamin T Lack, Garrett R Jackson, Vani J Sabesan.
       Background: Women continue to make up a minority of orthopedic surgeons, especially shoulder and elbow surgeons. There exists no study that investigates the effect of gender on one's academic career as a shoulder and elbow orthopedic surgeon, which was the purpose of this cross-sectional study.
    Methods: The American Shoulder and Elbow Surgeons website was used to identify surgeons. Demographics, education, and current professional roles were obtained using the websites of institutions, hospital employers, physicians, LinkedIn, and Doximity. Research productivity metrics were obtained using SCOPUS and Google Scholar. Outcome measures included current academic/leadership roles, and research productivity. Statistical analysis was performed using the Chi-squared test and Mann-Whitney U test.
    Results: Totally, 893 surgeons were identified, 60 being female (6.7%). Males had a significantly higher average h-index (P = 0.003), total number of publications (P = 0.019), citations (P = 0.03) and ASES membership ranks than female surgeons (P = 0.037; P = 0.004). There were no significant differences between genders in current professional or leadership roles.
    Discussion: Female surgeons had a significantly lower number of citations, publications, and h-index but equal leadership positions such as fellowship director, residency director, chief of service, and department chair compared to their male counterparts.
    Level of evidence: Level III, cross-sectional study.
    Keywords:  academic rank; career advancement; elbow; gender; research productivity; shoulder
    DOI:  https://doi.org/10.1177/17585732241310513
  67. Front Endocrinol (Lausanne). 2024 ;15 1475214
    A trend of osteocalcin in diabetes mellitus research: bibliometric and visualization analysis.
    Zixu Liu, Yuchen Mao, Kangping Yang, Shukai Wang, Fang Zou.
       Background: Osteocalcin has attracted attention for its potential role in diabetes management. However, there has been no bibliometric assessment of scientific progress in this field.
    Methods: We analysed 1680 articles retrieved from the Web of Science Core Collection (WoSCC) between 1 January 1986 and 10 May 2024 using various online tools.
    Result: These papers accumulated 42,714 citations,with an average of 25.43 citations per paper. Publication output increased sharply from 1991 onwards. The United States and China are at the forefront of this research area.
    Discussion: The keywords were grouped into four clusters: 'Differential and functional osteocalcin genes', 'Differential expression of osteocalcin genes in relation to diabetes mellitus', 'Role of osteocalcin in the assessment of osteoporosis and diabetes mellitus', and 'Indirect involvement of osteocalcin in metabolic processes'. Analysis using the VoS viewer suggests a shift in research focus towards the correlation between osteocalcin levels and diabetic complications, the clinical efficacy of therapeutic agents or vitamins in the treatment of osteoporosis in diabetic patients, and the mechanisms by which osteocalcin modulates insulin action. The proposed focus areas are "osteocalcin genes", "insulin regulation and osteoporosis ", "different populations", "diabetes-related complications" and "type 2 diabetes mellitus","effect of osteocalcin expression on insulin sensitivity as well as secretion","osteocalcin expression in different populations of diabetic patients and treatment-related studies".
    Keywords:  VOSviewer; bibliometric analysis; diabetes mellitus; osteocalcin; visualization
    DOI:  https://doi.org/10.3389/fendo.2024.1475214
  68. Complement Med Res. 2025 Jan 27. 1
    Research Trends of Traditional Chinese Medicine Therapies on Chronic Obstructive Pulmonary Disease: A Bibliometric Analysis.
    Chunyan Yang, Qiying He, Liuyang Huang, Hao Tian, Qin Luo, Guixing Xu, Mingsheng Sun, Sha Yang, Fanrong Liang, Pan Litao.
       BACKGROUND: Traditional Chinese Medicine (TCM) therapies have shown great improvement in chronic obstructive pulmonary disease (COPD) patients, yet no bibliometric analysis on TCM therapies for COPD exists.
    SUMMARY: A comprehensive literature search was conducted on TCM therapies for COPD within the past decade, utilizing the Web of Science (WOS) Core Collection and China National Knowledge Infrastructure (CNKI) databases. To analyze collaborative patterns among countries/regions, institutions, and authors, as well as identify influential references and emerging research trends, CiteSpace and VOSviewer software were employed. The dataset comprised 625 articles from WOS and 5,641 from CNKI, revealing a consistent growth in COPD-related TCM research over the past 10 years. China emerged as the leading contributor, with a predominant focus on TCM Universities. The American Journal of Respiratory and Critical Care Medicine was the most cited journal, while Medicine published the highest number of articles. Li, JS was the most prolific author, and Barnes, PJ was the most frequently cited researcher. Key studies by Leung RWM: Eur Respir J. 2013;41(5):1051-7, Li SY: BMC Complement Altern Med. 2012;12:197, and Polkey MI: Chest. 2018;153(5):1116-24 garnered significant attention. Keyword analysis highlighted the prominence of Tai Chi, Chinese herbal medicine, acupoint sticking, acupuncture, lung function, quality of life, and inflammation as core research themes.
    KEY MESSAGES: Research on TCM therapies for COPD has gained growing attention over the past decade. Among the most commonly studied TCM interventions are Tai Chi, Chinese herbal medicine, acupoint sticking, and acupuncture. Lung function, quality of life, and inflammation have emerged as key areas of investigation and are likely to remain focal points for future research endeavors.
    Keywords:  Bibliometric analysis; Bibliometrische Analyse; Chronic obstructive pulmonary disease; Chronisch-obstruktive Lungenerkrankung; CiteSpace; TCM-Therapien; Traditional Chinese Medicine therapies; VOSviewer
    DOI:  https://doi.org/10.1159/000541020
  69. J Asthma Allergy. 2025 ;18 85-100
    Bibliometric Analysis of Global Pediatric Research on Cow's Milk Protein Allergy.
    Xiaolan Lin, Yifan Chen, Weidong Lin.
       Background: Cow's milk protein allergy (CMPA) is a prevalent food allergy in early childhood, significantly impacting the quality of life for affected children. Current palliative measures, such as specialized formula milk, offer temporary relief but are costly and fail to address the underlying issue. Thus, there is a critical need to better understand CMPA and explore new treatment options.
    Methods: This study employed bibliometric methods to analyze global pediatric CMPA research and identify future directions for the first time. Visual analyses were conducted using VOS Viewer and CiteSpace software.
    Results: A total of 2040 articles published between 2000 and 2023 showed increasing annual publications. In this field of research, the Icahn School of Medicine at Mount Sinai has made significant contributions, with the most influential articles published in the Journal of Allergy and Clinical Immunology. Current research emphasizes personalized therapy, probiotics, and gut microbiota in CMPA.
    Conclusion: Future research will focus on microbiota-related personalized treatments, promising effective clinical interventions.
    Keywords:  Bibliometric analysis; Cow’s milk protein allergy; Gut microbiota; Pediatric
    DOI:  https://doi.org/10.2147/JAA.S487698
  70. PLoS Biol. 2025 Jan;23(1): e3002999
    Linking citation and retraction data reveals the demographics of scientific retractions among highly cited authors.
    John P A Ioannidis, Angelo Maria Pezzullo, Antonio Cristiano, Stefania Boccia, Jeroen Baas.
      Retractions are becoming increasingly common but still account for a small minority of published papers. It would be useful to generate databases where the presence of retractions can be linked to impact metrics of each scientist. We have thus incorporated retraction data in an updated Scopus-based database of highly cited scientists (top 2% in each scientific subfield according to a composite citation indicator). Using data from the Retraction Watch database (RWDB), retraction records were linked to Scopus citation data. Of 55,237 items in RWDB as of August 15, 2024, we excluded non-retractions, retractions clearly not due to any author error, retractions where the paper had been republished, and items not linkable to Scopus records. Eventually, 39,468 eligible retractions were linked to Scopus. Among 217,097 top-cited scientists in career-long impact and 223,152 in single recent year (2023) impact, 7,083 (3.3%) and 8,747 (4.0%), respectively, had at least 1 retraction. Scientists with retracted publications had younger publication age, higher self-citation rates, and larger publication volume than those without any retracted publications. Retractions were more common in the life sciences and rare or nonexistent in several other disciplines. In several developing countries, very high proportions of top-cited scientists had retractions (highest in Senegal (66.7%), Ecuador (28.6%), and Pakistan (27.8%) in career-long citation impact lists). Variability in retraction rates across fields and countries suggests differences in research practices, scrutiny, and ease of retraction. Addition of retraction data enhances the granularity of top-cited scientists' profiles, aiding in responsible research evaluation. However, caution is needed when interpreting retractions, as they do not always signify misconduct; further analysis on a case-by-case basis is essential. The database should hopefully provide a resource for meta-research and deeper insights into scientific practices.
    DOI:  https://doi.org/10.1371/journal.pbio.3002999
  71. World J Cardiol. 2025 Jan 26. 17(1): 102409
    Global hotspots and trends on environmental exposure and cardiovascular disease from 1999 to 2022.
    Xin-Jie Zhang, Qing Tan, Zheng-Yu Xu, Song Wen, Shu-Bo Chen.
       BACKGROUND: The increasing risk of cardiovascular disease (CVD) associated with worsening environmental exposure is a critical health concern garnering global research attention.
    AIM: To systematically assess the scope and characteristics of research on the relationship between environmental exposure and CVD.
    METHODS: A thorough examination of publications on the relationship between environmental exposure and CVD from 1999 to 2022 was carried out by extensively screening the literature using the Web of Science Core Collection. The language of the selected publications was standardized to English. Afterward, different academic tools such as CiteSpace, VOSviewer, HistCite, Python, Matplotlib, and Bibliometrix were utilized to examine the research trends in this field.
    RESULTS: The study's findings indicated a steady increase in scientific publications among the 1640 analyzed documents, peaking in 2022 with 197 publications. The United States emerged as the leading nation regarding high-quality publications and international collaboration. Harvard University was identified as the most prolific institution. "Environmental research" was the most frequently contributing journal, and Muenzel T was recognized as the top contributor. Current research hotspots are primarily concentrated on themes such as "cardiovascular disease", "exposure", "risk", "mortality", and "air pollution".
    CONCLUSION: This study highlights increasing research on the link between environmental exposure and CVD, identifying key exposures and diseases while emphasizing the need for further investigation into underlying mechanisms.
    Keywords:  Bibliometrics; Cardiovascular disease; CiteSpace; Environmental exposure; VOSviewer; Web of Science
    DOI:  https://doi.org/10.4330/wjc.v17.i1.102409
  72. Aesthetic Plast Surg. 2025 Jan 27.
    Global Landscape of Knowledge Mapping and Research Trends in Hyaluronic Acid for Wound Healing: A Bibliometric and Visualization Analysis (1952-2023).
    Sa'ed H Zyoud, Moyad Shahwan, Ammar A Jairoun.
      
    DOI:  https://doi.org/10.1007/s00266-025-04700-7
  73. Front Oncol. 2024 ;14 1521251
    Unveiling hotspots of emerging research in the miRNA-related mechanism underlying cancer through comprehensive bibliometric analysis with implications for precision medicine and non-invasive diagnostics.
    Zhirui Zhang, Wenhuan Song, Wenyu Chen, Wenze Cui, Wenyi Chen, Qinheng Zhang, Wenwen Ji, Yinglin Wang, Jiayi Wang, Wenhao Yu, Mingkun Yu, Tao Hao, Hong Jiang.
       Background and objective: MicroRNAs (miRNAs) are implicated in cancer by exerting roles in tumor growth, metastasis, and even drug resistance. The general trends of miRNA research in diverse cancers are not fully understood. In this work, miRNA-related research in colorectal cancer, prostate cancer, leukemia, and brain tumors was analyzed in search of key research trends with clinical potential.
    Methods: A bibliometric analysis of articles, spanning from 2014 to 2024, was carried out with the major focus laid on four types of cancers. The Co-citation network analysis, keyword bursts, and the collaborative pattern were done in VOSviewer and CiteSpace, respectively.
    Results: Colorectal cancer had the highest publication volume, with research primarily focusing on gene expression, extracellular vesicles, and non-coding RNAs. Prostate cancer showed a shift toward clinical applications, while leukemia and brain tumor research, though less extensive, highlighted miRNA's potential in early diagnosis and treatment. Co-citation analysis identified emerging research collaborations and key contributors.
    Conclusion: miRNA plays a pivotal role in cancer diagnosis, biomarker development, and therapeutic interventions. With advancements in non-invasive diagnostics and personalized medicine, miRNA offers significant potential for clinical applications. Future research should focus on miRNA's role in drug resistance and combination therapies to accelerate its clinical translation.
    Keywords:  bibliometric analysis; cancer diagnosis; microRNA; non-invasive diagnostics; personalized medicine
    DOI:  https://doi.org/10.3389/fonc.2024.1521251
  74. J Dent Sci. 2025 Jan;20(1): 672-677
    A scientometric study on research trends and characteristics of oral leukoplakia and oral lichen planus.
    Wei Liu, Xuemin Shen, Zhengyu Shen.
       Background/purpose: Oral leukoplakia (OLK) and oral lichen planus (OLP) represent two common oral potentially malignant disorders. It would be interesting to know scientific output and characteristics of studies on OLK and OLP.
    Materials and methods: This study aimed to investigate and compare scientometric characteristics of articles on OLK and OLP in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern.
    Results: A total of 1,191 and 2,288 papers on OLK and OLP were retrieved in the Scopus database, respectively. The total citation count was 31,859 and the h index was 75 for articles on OLK, and the total count was 55,491 and the h index was 93 for articles on OLP. For OLK research, oral cancer-related cancer risk, cancer diagnosis, carcinogenesis, prognosis, tumor marker, e.g. protein P53 and Ki-67, risk assessment, e.g. tongue site, tobacco and alcohol consumption were distinctive frequent keywords. For OLP research, drug efficacy, immunosuppressive agents, e.g. corticosteroid, triamcinolone acetonide, tacrolimus, and glucocorticoids, inflammation-related T lymphocyte, lymphocytic infiltration, cytokines, e.g. gamma interferon, tumor necrosis factor, and interleukin 6, complication, e.g. hepatitis C and diabetes mellitus, and scoring system-related visual analog scale, pain, anxiety, quality of life, depression, and questionnaire were distinctive keywords.
    Conclusion: This study elucidated the comprehensive identification and recognition of the important and relevant research topics concerned, and encouraged more studies in the field of OLK and OLP to refine management strategies of these diseases.
    Keywords:  Bibliometrics; Oral cancer development; Oral leukoplakia; Oral lichen planus; Research characteristics
    DOI:  https://doi.org/10.1016/j.jds.2024.08.025
  75. Br J Anaesth. 2025 Jan 30. pii: S0007-0912(25)00014-5. [Epub ahead of print]
    The enigma of journal impact factors: determinants of impact factors for journals in General and Internal Medicine, Surgery, and Anaesthesiology.
    Dileep N Lobo, Keith R Neal.
      
    Keywords:  Clarivate; bibliometrics; citation count; determinants; journal citation reports; journal impact factor; limitations
    DOI:  https://doi.org/10.1016/j.bja.2024.12.035
  76. Nanomedicine (Lond). 2025 Jan 29. 1-16
    Current views and trends of nanomaterials as vectors for gene delivery since the 21st century: a bibliometric analysis.
    Xiao Xiao, Sheng Yang, Ge Jiang, Shisheng He.
       BACKGROUND: Gene therapy is garnering increasing support due to its potential for a "once-delivered, lifelong benefit." The limitations of traditional gene delivery methods have spurred the advancement of bionanomaterials. Despite this progress, a thorough analysis of the evolution, current state, key contributors, focal studies, and future directions of nanomaterials in gene delivery remains absent.
    METHODS: This study scrutinizes articles from the Web of Science, spanning 1 January 2 000, to 31 December 2023, employing various online tools for analysis and visualization.
    RESULTS: The 21st century has witnessed consistent growth in scholarly work in this domain globally, with notable contributions from China and the US. At the same time, the Chinese Academy of Sciences (CAS), Harvard University, and Massachusetts Institute of Technology (MIT) have emerged as the most productive institutions, with CAS's academician Weihong Tan becoming the field's leading author. While drug delivery and nanoparticles (NPs) have been central themes for two decades, the research focus has shifted from modifying NPs and ultrafine particles to exploring polymer-hybrid NPs, mRNA vaccines, immune responses, green synthesis, and CRISPR/Cas tools.
    CONCLUSIONS: This shift marks the transition from nanomaterials to bionanomaterials. The insights provided by this research offer a comprehensive overview of the field and valuable guidance for future investigations.
    Keywords:  Nanomaterials; bibliometrics; gene delivery; global research trends; vectors
    DOI:  https://doi.org/10.1080/17435889.2025.2457781
  77. J Contemp Dent Pract. 2024 Oct 01. 25(10): 941-949
    A Scientometric Exploration of the Socket-shield Technique in Oral Implantology: Trends and Spatiotemporal Dynamics.
    Carla Buchelli-Ramirez, Randy Samillán-Arbulú, Fran Espinoza-Carhuancho, Frank Mayta-Tovalino.
       AIM: The socket-shield technique arises from the efforts to stop the dimensional changes of the bone crest and gingival tissues. This technique consists of leaving a vestibular fragment of a naturally attached root with the purpose of keeping the crestal bone nourished through the periodontium. The aim of this research was to perform a scientometric analysis of the scientific production on the socket-shield technique in oral implantology.
    MATERIALS AND METHODS: A descriptive, observational study was carried out with a scientometric approach. A specialized search was performed, with variants of the keywords extracted from the Medical Subject Heading (MeSH) thesaurus of PubMed and the Embase thesaurus. For Web of Science (WOS) data, including only documents as original articles, reviews, and as sources corresponding to the subject. Production, trends, and impact indicators were performed.
    RESULTS: During the study period 2000-2023, the scientific production of research increased in the last 3 years. The journal with the highest scientific production of research was "Clinical Oral Implant Research", and the USA was found to be the dominant country in scientific production. Initially, the development of the research topic of interest was "tooth extraction and socket" between 2000 and 2015, and "dental implants and alveolar ridge preservation" between 2015 and 2023.
    CONCLUSION: The socket-shield technique in oral implantology is a growing field of research, with extensive international collaboration and significant impact in terms of citations. As this growth continues, we are likely to see even more advances and discoveries in this field.
    CLINICAL SIGNIFICANCE: The study on the socket-shield technique in oral implantology highlights its clinical importance by demonstrating that this technique can preserve crestal bone and gingival tissues, improving the stability, and esthetics of dental implants. In addition, its growing research and international collaboration underscore its relevance and potential for future innovations in the field. How to cite this article: Buchelli-Ramirez C, Samillán-Arbulú R, Espinoza-Carhuancho F, et al. A Scientometric Exploration of the Socket-shield Technique in Oral Implantology: Trends and Spatiotemporal Dynamics. J Contemp Dent Pract 2024;25(10):941-949.
    Keywords:  Bibliometrics; Dental implant Socket-shield.
    DOI:  https://doi.org/10.5005/jp-journals-10024-3768
  78. Med J Armed Forces India. 2025 Jan-Feb;81(1):81(1): 32-38
    Vexatious and euphemistic affairs in retractions of scientific publications: A pilot study.
    Jyotindu Debnath, Debjyoti Debnath, Seema Patrikar.
       Background: An increasing number of retractions have been published in the recent past which may be conforming to the large number publications being added on a daily basis. Concerns have been flagged time and again regarding comprehensiveness and utility of retraction notices.
    Methods: Retraction notices published in PubMed in Jan 23 were analyzed for journal, publisher, article, country affiliation of authors, month of publication, who raised concern, main and additional reason for retraction, completeness of retraction notice, editors/authors requesting for retraction, agreement between authors and editors, and the number of citations received.
    Results: A total of 295 retraction notices published in PubMed in Jan 2023 by 110 journals (which included 24 publishers and 9 standalone journals) were analyzed. Sixty-four percent of journals published single retraction notice. The highest number of retractions by a single journal was 70. Only 31% of retraction notices gave complete details. Editors requested for retraction in 88% cases. Eighty-four percent of the articles received at least one citation. In 71% of cases, it is not known who raised the concern. Reasons for retraction were compromised peer review (37%), plagiarism (20%), image manipulation (13%), data reliability (8%), authorship dispute (6%), methodology issues (4%), and so on. Twenty-seven percent of cases had more than one reason. Plagiarism of figures constituted 84% of total plagiarism cases. Fifty-eight of 59 plagiarism cases were described indirectly despite clear evidence. Authors and editors agreed for retraction in 25% of cases, and no information was available in 36% cases.
    Conclusion: A substantial number of retraction notices are incomplete, vague, and euphemistic. Plagiarism of figures/images is an emerging threat.
    Keywords:  Characteristics; Euphemism; Retraction notices; Scientific publications
    DOI:  https://doi.org/10.1016/j.mjafi.2023.07.005
  79. Microorganisms. 2025 Jan 17. pii: 187. [Epub ahead of print]13(1):
    Four Decades of Bacillus Biofertilizers: Advances and Future Prospects in Agriculture.
    Xinmai Wu, Yan Liu, Baolei Jia, Lili Tao, Han Li, Jingbang Wang, Ziqi Yuan, Xiaobao Sun, Yanlai Yao.
      Over the past four decades, Bacillus biofertilizers, which are microbial formulations based on Bacillus species, have significantly contributed to sustainable agriculture by enhancing crop growth, improving soil health, and reducing the dependency on chemical fertilizers. Bacillus species, particularly known for their ability to promote plant growth, fix nitrogen, solubilize phosphorus, and produce growth-promoting substances such as phytohormones and antibiotics, have emerged as key players in the development of eco-friendly agricultural solutions. This research utilizes bibliometric analysis based on 3,242 documents sourced from the Web of Science database to map the development, key contributions, and innovation within the field from 1985 to 2023. This study identifies exponential growth in research output, particularly from 2003 onwards, indicating a robust interest and expanding research base predominantly in China, India, and the United States. We segmented the research timeline into three distinct phases, each marked by varying growth rates and research foci. This paper presents novel insights into the geographical and institutional distributions of research, highlighting the predominant role of developing countries in advancing Bacillus-based technologies. Key research hotspots have evolved from basic applications to complex interactions involving synthetic microbial communities and advanced multi-omics techniques. Our findings demonstrate a trend towards more strategic and technologically integrated approaches to developing Bacillus biofertilizers, reflecting broader shifts towards more sustainable agricultural systems. This study not only charts historical progress, but also proposes future research trajectories aimed at enhancing the application and effectiveness of microbial fertilizers across diverse ecosystems.
    Keywords:  Bacillus-based microbial fertilizers; PGPR; bibliometric; multi-omics; sustainable agriculture; synthetic microbial communities
    DOI:  https://doi.org/10.3390/microorganisms13010187
  80. Soc Sci Med. 2025 Jan 13. pii: S0277-9536(25)00025-5. [Epub ahead of print]367 117696
    Health insurance expansion and academic production: The case of Medicare Part D legislation.
    Guanting Yi.
      Understanding how market demand influences academic research is crucial for comprehending the innovation process and informing policy decisions. This study examines the impact of the 2003 Medicare Part D legislation on biomedical journal article production across diseases. Using a difference-in-differences framework, together with a sample of over 2 million original research articles published between 1987 and 2015 sourced from PubMed database, I find a relatively 18.5% increase in academic publications on diseases more common among Medicare beneficiaries, indicating responsiveness to market demand. Further analysis shows that non-government funding significantly contributed to this increase. However, these additional publications tend to be of lower quality, as measured by citations, patent citations, and journal impact factors. This suggests a trade-off between the quantity and quality of research outputs. Overall, this paper highlights how market demand influences academic production, demonstrating that healthcare policy changes, such as Medicare Part D, can spur academic research output and reshape research focus. Policymakers should consider these spillover effects to balance research quantity and quality while ensuring equitable benefits.
    Keywords:  Academic production; Market demand; Medicare Part D; Research publication
    DOI:  https://doi.org/10.1016/j.socscimed.2025.117696
  81. Surg Open Sci. 2024 Aug;20 151-155
    Revolutionizing medical education: Surgery takes the lead in virtual reality research.
    M A Wolf, M Mergen, P Winter, S Landgraeber, P Orth.
       Objectives: Advancements in technology have spurred a transformative shift in medical education, with virtual reality (VR) emerging as a powerful tool for enhancing the learning experience. This study analyses the publications of VR in medical education, focusing on differences within different medical specialties.
    Design: Using specific search terms, all studies published on VR in medical education listed in the Web of Science databases were included. All identified publications were analysed in order to draw comparative conclusions regarding their qualitative and quantitative scientific merit.
    Results: Since the first publication in 1993 and until the year 2022, there have been 1534 publications on VR in medical education. Over the years, the annual publication rate has increased almost exponentially. The studies have in total been cited 42,655 times (average 27.64 citations/publication). The leading medical field was surgery (415 publications), followed by internal medicine (117 publications), neurology (77 publications) and radiology and nuclear medicine (75 publications). Internationally, the United States (560 publications), the United Kingdom (179 publications), Canada (156 publications), Germany (139 publications) and China (100 publications) are the leading countries in this field. 37.1 % of the publications reported having received funding. Among the 100 organizations with the highest number of grants, only 8 were private companies.
    Conclusion: During the last 30 years, there has been a consistent rise in publications, with a notable surge observed in 2016 and 2020. The majority of the studies centered on surgical concerns. However, only a small proportion received financial support, which was particularly evident for funding originating from the private sector.
    Keywords:  Digital; Medical education; Surgery; VR; Virtual reality
    DOI:  https://doi.org/10.1016/j.sopen.2024.06.013
  82. BMJ Oncol. 2024 ;3(1): e000200
    Sex and authorship in global cancer research.
    Miriam Mutebi, Grant Lewison, Deborah Mukherji, Nazik Hammad, Verna Vanderpuye, Erica Liebermann, Winnie K W So, Julie Torode, Richard Sullivan, Ophira Ginsburg.
       Introduction: Research is an essential pillar of cancer control and key in shaping regional cancer control agendas. Imbalances in science and technology in terms of lack of female participation have been well documented. However, there is little evidence about country-level female participation in cancer research.
    Methodology: Through a complex filter, cancer research papers were identified and grouped by countries and sex of the first and last authors of each paper and analysed by the percentage of females in these positions alongside other parameters.
    Results: Our analysis of 56 countries' outputs, in 2009, revealed that females were the first authors in 37.2% and last authors in 23.3% of papers. In 2019, females were the first author in 41.6% and last author in 29.4% of papers. Females increased as first authors by 26%, and as last authors by 12% between these two time periods. The top performing countries in terms female/male parity for first or last authorship were in Eastern and Southern Europe as well as Latin American countries.From 2009 to 2019, the highest proportion of females as first and last authors were from low-income and middle-income countries in Latin America and Eastern Europe.Females were more likely to publish in lower impact journals and were less likely to be cited compared to males.
    Conclusions: Globally, progress in female's authorship in oncology research has been uneven. More research is needed to understand the reasons behind this. Advancing diversity and equity in research leadership and authorship will be essential to address the complex challenges of cancer globally.
    Keywords:  Health economics; Medical oncology
    DOI:  https://doi.org/10.1136/bmjonc-2023-000200
  83. PLoS One. 2025 ;20(1): e0316890
    Patterns of diversity in biomedical coauthorships: An analysis across authors' ethnicity, gender, age, and expertise.
    Apratim Mishra, Haejin Lee, Sullam Jeoung, Vetle I Torvik, Jana Diesner.
      Multiple studies have linked diversity in scientific collaborations to innovative and impactful research. Here, we explore how different diversity indices-ethnicity, gender, academic age, and topical expertise-interact and thereby influence scientific impact. Leveraging nearly 900,000 biomedical journal articles from PubMed, published in major journals between 1991 and 2014, we investigate the nuanced relationships among these diversity indices and their collective influence on research outcomes. By systematically varying model parametrizations, we assess the robustness of the observed relationships and examine multiple methodological choices. Our findings reveal a consistent pattern of demographic homophily, where scientists tend to collaborate with others who share similar ethnic and gender backgrounds. While each diversity index correlates significantly with impact when considered individually, gender diversity and topical expertise emerge as the strongest positive predictors of impact after accounting for key covariates. However, the association between diversity and impact is moderated by the number of collaborating authors, with larger teams sometimes showing opposite trends due to interactions between the computed diversity indices and team size. Despite this complexity, the practical drivers of scientific impact for an article remain the journal of publication, authors' prior citation rate, and the number of co-authors. On further examining expertise diversity through three separate dimensions: variety, balance, and disparity, our findings indicate that impactful teams balance a wide range of subject matter expertise while maintaining a focused connection on closely related topics. These findings highlight the importance of strategic team composition and underline the significance of team diversity in scientific research.
    DOI:  https://doi.org/10.1371/journal.pone.0316890
  84. J Dent Sci. 2025 Jan;20(1): 667-671
    A scientometric study on research trends and characteristics of discoid lupus erythematosus.
    Yun Wang, Yuhan Zhu, Chenping Zhang, Wei Liu.
       Background/purpose: Discoid lupus erythematosus (DLE) serves as an interdisciplinary disease involved in dermatology and stomatology in many cases. The purpose of this study was to analyze the scientometric characteristics and research trends of DLE.
    Materials and methods: All the papers on DLE were comprehensively retrieved from the Scopus database. Discipline comparison (dermatology versus others) and chronological comparison (before 2005 versus 2005-2024) were performed, so that the number of papers can be to some extent compared in the analysis.
    Results: Among all the 1239 papers on DLE, 738 (59.6 %) were published by dermatologists. Diagnosis aspect, skin manifestation, facial dermatoses, scar formation, hair loss, epiluminescence microscopy, dermoepidermal junction, arthralgia, anamnesis, young adult, Ro antibody, and dermoscopy were distinctive keywords for dermatologists; While Mouth mucosa, mouth diseases, lip neoplasms, eyelid disease, blepharitis, conjunctivitis, autoantibody, blood, neutrophil, fever, sex difference, preschool child were distinctive keywords for other scholars. Treatment response, dapsone, etretin, clobetasol, mycophenolate mofetil, glucocorticoid, triamcinolone, and drug safety were therapeutic keywords for dermatologists. Whereas quinacrine, alpha tocopherol, hydrocortisone, adverse drug reaction were therapeutic keywords for other scholars. The trend has changed to complication, disease duration, young adult, dermatitis, pruritus, antibody titer, Ro antibody, anamnesis, dermoscopy, arthralgia, dermoepidermal junction, keratosis, and African American, drug withdrawal, tacrolimus, mycophenolate mofetil, etretin, clobetasol, cyclophosphamide, and drug safety after 2005.
    Conclusion: This scientometric study elucidated the current scenario and research trends of DLE, and would help in improving in reciprocal collaboration and communication for investigations on this disease.
    Keywords:  Bibliometrics; Dermatologists; Discoid lupus erythematosus; Drug therapy; Research characteristics
    DOI:  https://doi.org/10.1016/j.jds.2024.10.003
  85. J Dent Sci. 2025 Jan;20(1): 254-260
    A scientometric study of syphilis research by dermatologists and stomatologists: Underpinning their roles in public health.
    Yeqiang Li, Chenxi Li, Xuemin Shen, Zhengyu Shen, Wei Liu.
       Background/Purpose: The Lancet Infectious Diseases launched a call to action for dermatologists in the rise of syphilis. In practice, dermatologists and stomatologists perform early diagnoses of syphilis and refer patients to adequate treatment.
    Materials and methods: This scientometric study aimed to investigate and compare research trends and characteristics of syphilis publications by dermatologists and stomatologists in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern.
    Results: Among 18,120 papers on syphilis, 1981 (10.9%) and 201 (1.1%) were published by dermatologists and stomatologists, respectively. The total citation count was 18,629 and 2,376 with an h index of 52 and 25 for publications by dermatologists and stomatologists, respectively. Common keywords in papers by both dermatologists and stomatologists included male, Treponema pallidum, benzathine penicillin, differential diagnosis, human immunodeficiency virus, secondary syphilis, syphilis serology, cutaneous syphilis, neurosyphilis, congenital syphilis, lymphadenopathy, chancre, gonorrhea, rash, erythema, and papule. Distinctive keywords used by dermatologists included infant, pregnancy complications, lymphocytic infiltration, spirochete, and genetics. Keywords that included questionnaire, awareness, infection risk, attitude to health, sexual health, oral sex, and unprotected sex were used by stomatologists.
    Conclusion: In the modern context, both dermatologists and stomatologists play important roles in providing early recognition and timely diagnosis of syphilis, advocating for public health campaigns aimed at increasing awareness, and improving access to care for at-risk patient populations.
    Keywords:  Bibliometrics; Cutaneous; Oral mucosa; Research trends; Sexually transmitted diseases; Syphilis
    DOI:  https://doi.org/10.1016/j.jds.2024.08.001
  86. JCO Glob Oncol. 2025 Jan;11 e2400320
    Landscape of Global Pediatric Oncology Publications: A Cross-Sectional Analysis.
    María Fernanda García Garza, Oscar Gutiérrez Treviño, Saman K Hashmi, Carlos Rodríguez-Galindo, Daniel C Moreira.
       PURPOSE: The academic field of global pediatric oncology is expanding as cancer becomes increasingly recognized as a global health priority for children and adolescents. Here, we aimed to explore the representation of authors, the geographic distribution of research, and the research approaches being used in global pediatric oncology.
    METHODS: Articles published in JCO Global Oncology (JCO GO) and Pediatric Blood and Cancer on the topic of global pediatric oncology were analyzed. For each article, data were collected on the study design, the research location, and the authorship demographics. Descriptive frequencies were reported for all items.
    RESULTS: Overall, 296 studies met the inclusion criteria to be considered relevant for global pediatric oncology. Of these, 259 (87.5%) were research articles. Of the research articles, 228 (88.0%) were observational and 117 (51.3%) were retrospective cohort analyses. Thirty-eight studies (12.8%) had a global focus or were unrelated to a geographic context, 54 (18.2%) were regional, and 204 (68.9%) were specific to a single country. Females represented 163 (55.8%) of first authors, 138 (46.6%) of senior authors, and 159 (53.7%) of corresponding authors. Furthermore, 121 (41.4%) first authors, 163 (55.1%) last authors, and 142 (48.0%) senior authors were from high-income countries (HICs). The United States (n = 81) and India (n = 40) had the most corresponding authors. Thirty-six (17.6%) articles had research conducted in low- and middle-income countries (LMICs), and the first, senior, and corresponding authors were from HICs.
    CONCLUSION: Our analysis shows that researchers from LMICs are under-represented as authors of global pediatric oncology publications. Further studies are needed to evaluate the factors that contribute to inequalities in global pediatric oncology research.
    DOI:  https://doi.org/10.1200/GO-24-00320
  87. J Hand Microsurg. 2025 Jan;17(1): 100161
    Vascularised Composite Allotransplantation - A guide to optimal dissemination of scientific outputs.
    C M Hehir, G P Dowling, G G Calpin, M O'Connor, L Kelly, C S Honeyman, H L Stark, R T Dolan.
       Purpose: The impact of academic research is not just important within the clinical domain but within society as a whole. Altmetric Attention Score (AAS) offers a means of assessing how scholarly outputs are interacted with online. Vascularised Composite Allotransplantation (VCA) is a modern but rapidly evolving topic which encompasses a broad range of complex and clinically significant surgical interventions. Primarily VCA is utilised in the reconstruction of complex, composite tissue defects, including limb and face transplantation. There is also a growing interest in the role of VCA as an early means of real-time immuno-monitoring, in sentinel skin flap transplant (SSF).
    Materials & methods: In July 2024, a search was conducted using the Altmetric Explorer (AE) database using the search term 'vascular-composite' AND 'allograft' OR 'allotransplant'. A simultaneous literature search was carried out using Web of Science (WoS) database utilising the same search terms with extraction of traditional citation-based metrics as well as relevant 'meso' and 'micro' subject headings. Corresponding citation-based metrics were extracted utilising SCImago. Data was compiled and analysed using a linear regression model with level of significance set at p < 0.05.
    Results: The Top 100 (T100) performing articles relating to VCA displayed a mean Altmetric Attention Score (AAS) of 3.31. All T100 papers were published in the English language. Sixty percent (n = 60) of T100 papers were published in Q1 Journals. News outlet mentions (r = 6.95), blog mentions (r = 6.20), and Twitter/X mentions (r = 0.52) demonstrated the greatest positive impact on AAS upon application of a linear regression model (p < 0.05).
    Conclusion: Altmetric Scores offer a means of appraising the impact of research outputs in both academic and societal domains. Such modern metrics are useful in evolving topics such as VCA as AAS is not dependent on citation counts. Publishing of outputs in high quartile, open access journals with timely utilisation of news and social media outlets should be utilised by researchers aiming to maximise dissemination of research outputs in the field of VCA.
    Keywords:  Altmetric analysis; Sentinel skin flap; Transplant; Vascularised composite allograft
    DOI:  https://doi.org/10.1016/j.jham.2024.100161
  88. Crit Rev Food Sci Nutr. 2025 Jan 29. 1-15
    Mechanistic and bibliometric insights into RpoS-mediated biofilm regulation and its strategic role in food safety applications.
    Shirin Akter, Md Ashikur Rahman, Md Ashrafudoulla, A G M Sofi Uddin Mahamud, Md Anamul Hasan Chowdhury, Sang-Do Ha.
      Biofilm, complex structures formed by microorganisms within an extracellular polymeric matrix, pose significant challenges in the sector by harboring dangerous pathogens and complicating decontamination, thereby increasing the risk of foodborne illnesses. This article provides a comprehensive review of the sigma factor, rpoS's role in biofilm development, specifically in gram-negative bacteria, and how the genetic, environmental, and regulatory elements influence rpoS activity with its critical role in bacterial stress responses. Our findings reveal that rpoS is a pivotal regulator of biofilm formation, enhancing bacterial survival in adverse conditions. Key factors affecting rpoS activity include oxidative and osmotic stress and nutrient availability. Understanding rpoS-mediated regulatory pathways is essential for developing targeted biofilm management strategies to improve food quality and safety. Furthermore, a bibliometric analysis highlights significant research trends and gaps in the literature, guiding future research directions. Future research should focus on detailed mechanistic studies of rpoS-mediated biofilm regulation, the development of specific rpoS inhibitors, and innovative approaches like biofilm-resistant surface coatings. This knowledge can lead to more effective contamination prevention and overall food safety enhancements.
    Keywords:  Biofilm; RpoS; bibliometric analysis; food industries; sigma factor
    DOI:  https://doi.org/10.1080/10408398.2025.2458755
  89. Acta Neuropsychiatr. 2025 Jan 30. 37 e7
    A comprehensive bibliographic study on mental illness.
    Yuanzhao Ding, Shan Chen.
      This study presents a comprehensive analysis of recent mental illness research by utilizing an advanced bibliographic method capable of analyzing up to 12,965 papers indexed in the Web of Science database, overcoming the limitations of traditional tools like VOSviewer, which typically analyze fewer than 1,000 papers. By examining a vast dataset, this study identifies key trends, significant keywords, and prominent contributors, including leading researchers, universities, and countries/regions, in the field of mental illness research. Additionally, the study highlights eight major contributors to mental health problems, offering critical insights into the field’s current state. The findings underscore the importance of advanced bibliographic methods in providing a more detailed and accurate overview of mental illness research. This analysis not only enhances the understanding of young scholars entering the field but also uncovers significant trends and identifies notable gaps in the literature. The study advocates for continued innovation and interdisciplinary collaboration to deepen understanding and address unresolved challenges in mental health research.
    Keywords:  Mental illness; Web of Science; bibliographic study; mental health research; psychological disorders
    DOI:  https://doi.org/10.1017/neu.2024.64
  90. Ann Neurosci. 2025 Jan 25. 09727531241306571
    A Comprehensive Review of Psychosocial, Academic, and Psychological Issues Faced by University Students in India.
    Mubashir Gull, Navneet Kaur, Wael M F Abuhasan, Suneetha Kandi, Sidharth Murali Nair.
       Background: University students confront a wide range of issues during their pursuit of education. Understanding these issues is essential for developing effective treatments and support systems.
    Purpose: This study aims to delineate the landscape of scholarly literature pertaining to psychosocial, academic, and psychological issues among university students. It further identifies key journals and publishing trends within the fields, thereby significantly contributing to this domain. Additionally, this study outlines the scientific field networks that offer theoretical and conceptual foundations for exploring the psychosocial, academic, and psychological challenges faced by university students. Furthermore, it also intends to systematically categorise various types of problems encountered by university students in India.
    Methods: To systematically gather and investigate the problems encountered by students in higher education, this study utilises bibliometric analysis, highlighting topics related to mental health. Data were extracted from Scopus and Web of Sciences databases.
    Results: The analysis of the literature yielded 12 overarching categories related to challenges faced by university students: stress, academic stress, depression, anxiety, internet/ smartphone addiction/ gaming disorder, low self-esteem, loneliness, insomnia, suicidal ideations, eating disorders, drug addiction, adjustment issues.
    Conclusion: Academic institutions should prioritise student mental health, as it affects academic performance and can lead to psychological disorders. Universities need Guidance and Counselling Cells staffed with professionals to help students manage psychosocial, academic, and psychological challenges.
    Keywords:  Distress; India; anxiety; social dysfunction; suicide; youth
    DOI:  https://doi.org/10.1177/09727531241306571
  91. Hellenic J Cardiol. 2025 Jan 24. pii: S1109-9666(25)00005-3. [Epub ahead of print]
    Why does cardiology have many extreme publishing authors?
    John P A Ioannidis.
      Under diverse contributing factors in different scientific micro-environments, the number of authors who publish extreme numbers of full articles in a single year has increased. Cardiology is the subfield that has the largest share of authors with extreme publishing behavior than any other subfield in science (outside physics). Between 2000 and 2022, 137 authors in the subfield of Cardiovascular System (CVS, Science-Metrix classification) have published over 60 full articles in at least one calendar year and are also highly-cited. The majority (70/137) are from Europe. All 7 countries with the highest prevalence of CVS extreme publishing authors per million population are European countries. Issues of massive authorship of papers by administrative leaders are discussed, including the arguments in favor of sustaining this practice - and a refutation of these arguments. Other major contributors to the phenomenon are publications from clinical trials and epidemiological studies and massive authorship of highly-cited guidelines. Micro-environments are instrumental in creating extreme publishing behavior in both developed and less developed countries. Listing of contributions does not solve the problem since contributions are also gamed; metrics that probe gaming are nevertheless available. Eventually, authorship carries both credit and accountability. Number of publications is a metric that can be heavily gamed. Emphasis should be given to what makes major impact on science and human lives.
    DOI:  https://doi.org/10.1016/j.hjc.2025.01.005
  92. Integr Environ Assess Manag. 2025 Jan 06. pii: vjae050. [Epub ahead of print]
    Global advances and innovations in bacteria-based biosorption for heavy metal remediation: a bibliometric and analytical perspective.
    Syarifuddin Syarifuddin, Sri Suryani, Dahlang Tahir.
      Industrialization and urbanization have significantly escalated the discharge of heavy metals into aquatic environments, posing serious ecological and public health risks. This study explores the global research landscape of bacterial biosorption for heavy metal removal, emphasizing advancements in methodologies and technologies that have redefined this field. A bibliometric analysis of 298 publications (1987-2024) was conducted to identify key trends, collaboration networks, and innovations. Notable advancements include the integration of nanotechnology, which has enhanced adsorption efficiency and selectivity for specific metals, and genetic engineering approaches that optimize bacterial strains for higher adsorption capacity. Furthermore, these developments have transformed traditional remediation strategies by providing cost-effective, sustainable, and scalable solutions for industries such as textiles, mining, and energy production. This study underscores the practical relevance of bacterial biosorption in wastewater treatment, achieving removal efficiencies exceeding 99% in some cases, as demonstrated by Aspergillus versicolor and Shewanella oneidensis MR-1. By bridging scientific innovation with environmental sustainability, this research highlights bacterial biosorption as a pivotal green technology, offering actionable insights for industrial applications and global sustainability goals.
    Keywords:  bacterial biosorption; genetic engineering; heavy metal remediation; nanotechnology; sustainable wastewater treatment
    DOI:  https://doi.org/10.1093/inteam/vjae050
  93. J Surg Res. 2025 Jan 28. pii: S0022-4804(25)00019-8. [Epub ahead of print]
    Reevaluating Gender Disparities in Academic Productivity in Plastic Surgery: Women Produce Impactful Research, Yet Their Output Falls Short.
    Georgios Karamitros, Gregory A Lamaris, Michael P Grant, Heather J Furnas.
      
    DOI:  https://doi.org/10.1016/j.jss.2024.12.057
  94. Res Dev Disabil. 2025 Jan 25. pii: S0891-4222(25)00003-4. [Epub ahead of print]158 104919
    Beyond disability: A scientometric review of quality of life in developmental disabilities.
    Riccardo Cavallaro, Alessandro Carollo, Giulia Balboni, Laura E Gómez, Dagmara Dimitriou, Gianluca Esposito.
      Quality of Life (QoL) is a crucial concept that pertains to an individual's perception of their position in life. In the context of developmental disabilities, QoL is pivotal for improving evidence-based practices, providing support and organizing services for individuals, thereby enabling them to achieve their potential with dignity and equality. Despite its importance, QoL has often not been the primary focus in many studies on developmental disabilities and remains less developed compared to other research areas. This study aims to provide a comprehensive understanding of the existing knowledge in this thematic area. A document co-citation analysis was conducted to identify the most impactful publications and main thematic domains of research in the literature (N = 2141 documents and their 97,547 citations). A total of 21 impactful documents were identified, most of which focused on issues related to the conceptualization and assessment of QoL. Nine major thematic domains of research were outlined. In line with the impactful publications, some research themes focused on conceptual issues (e.g., self-reported QoL and QoL reported from others) and assessment approaches. Furthermore, the literature has transitioned towards broadening the QoL perspective in the context of family and social systems. The study provides an overview of how QoL has been studied in the context of developmental disabilities, highlighting the interdependence of individuals, families, and communities in ensuring a fulfilling life through the lens of QoL.
    Keywords:  Developmental disabilities; Intellectual disabilities; Quality of life; Quality of life support models; Scientometrics; Social services
    DOI:  https://doi.org/10.1016/j.ridd.2025.104919
  95. Proc Natl Acad Sci U S A. 2025 Feb 04. 122(5): e2401231121
    The misalignment of incentives in academic publishing and implications for journal reform.
    Jennifer S Trueblood, David B Allison, Sarahanne M Field, Ayelet Fishbach, Stefan D M Gaillard, Gerd Gigerenzer, William R Holmes, Stephan Lewandowsky, Dora Matzke, Mary C Murphy, Sebastian Musslick, Vencislav Popov, Adina L Roskies, Judith Ter Schure, Andrei R Teodorescu.
      For most researchers, academic publishing serves two goals that are often misaligned-knowledge dissemination and establishing scientific credentials. While both goals can encourage research with significant depth and scope, the latter can also pressure scholars to maximize publication metrics. Commercial publishing companies have capitalized on the centrality of publishing to the scientific enterprises of knowledge dissemination and academic recognition to extract large profits from academia by leveraging unpaid services from reviewers, creating financial barriers to research dissemination, and imposing substantial fees for open access. We present a set of perspectives exploring alternative models for communicating and disseminating scientific research. Acknowledging that the success of new publishing models depends on their impact on existing approaches for assigning academic credit that often prioritize prestigious publications and metrics such as citations and impact factors, we also provide various viewpoints on reforming academic evaluation.
    Keywords:  academic journals; academic prestige economy; alternative publishing models; publication bias; publish or perish culture
    DOI:  https://doi.org/10.1073/pnas.2401231121
  96. J Food Sci Technol. 2025 Feb;62(2): 240-253
    Chitosan research progress for smart packaging applications: a literature review.
    Dahlang Tahir, Inayatul Mutmainna, Heryanto Heryanto, Paulus Lobo Gareso, Sri Suryani, Bualkar Abdullah.
      The environmental crisis was brought on by composites made of synthetic materials that are not biodegradable. Eco-friendly replacement materials for non-biodegradable composites is biodegradable composites. The poisonous remnants are avoided because of how the environment breaks them down. Biodegradable polymers are quickly broken down by bacterial breakdown. Smart packaging has been created to enable consumers to comprehend food conditions in real-time due to the growth of new technologies and consumer desire for wholesome and safe foods. This review highlights and discusses the development, type, and direction of research progress of chitosan research in the application of smart packaging, using bibliometric analysis with time intervals from 2006 to 2023. In 2006, this research began to be developed with India, China, the United States, Iran, and Egypt as the five most influential countries. From the results of keyword analysis, it was found that in addition to studying the general characteristics of smart packaging, there are currently many developments related to smart packaging materials and the effect of adding other materials to the film. The keyword analysis also revealed the current trends and future directions of chitosan research in smart packaging applications, providing valuable insights for researchers and professionals.
    Keywords:  Bioplastic; Chitosan; Smart packaging; pH
    DOI:  https://doi.org/10.1007/s13197-024-06135-5
  97. Aten Primaria. 2025 Jan 25. pii: S0212-6567(24)00259-2. [Epub ahead of print]57(5): 103117
    [Health science students as RENACYT researchers at a peruvian university: A bibliometric study].
    Gustavo Canales Sermeño, Marisel Roxana Valenzuela Ramos, Margarita Medaly Barrios Sayritupac, César Jesús Eras Lévano.
      
    DOI:  https://doi.org/10.1016/j.aprim.2024.103117
  98. Int J Radiat Oncol Biol Phys. 2025 Jan 25. pii: S0360-3016(25)00056-2. [Epub ahead of print]
    SEMI-AUTOMATED EXTRACTION OF RESEARCH TOPICS AND TRENDS FROM NCI FUNDING IN RADIOLOGICAL SCIENCES FROM 2000-2020.
    Mark H Nguyen, Peter G Beidler, Joseph Tsai, August Anderson, Daniel Chen, Paul E Kinahan, John Kang.
       BACKGROUND: Investigators and funding organizations desire knowledge on topics and trends in publicly funded research but current efforts for manual categorization have been limited in breadth and depth of understanding.
    PURPOSE: We present a semi-automated analysis of 21 years of R-type National Cancer Institute (NCI) grants to departments of radiation oncology and radiology using natural language processing (NLP).
    METHODS: We selected all non-education R-type NCI grants from 2000 to 2020 awarded to departments of radiation oncology/radiology with affiliated schools of medicine. We used pre-trained word embedding vectors to represent each grant abstract. A sequential clustering algorithm assigned each grant to one of 60 clusters representing research topics; we repeated the same workflow for 15 clusters for comparison. Each cluster was then manually named using the top words and closest documents to each cluster centroid. The interpretability of document embeddings was evaluated by projecting them onto 2 dimensions. Changes in clusters over time were used to examine temporal funding trends.
    RESULTS: We included 5,874 grants totaling 1.9 billion dollars of NCI funding over 21 years. The human-model agreement was similar to the human interrater agreement. Two-dimensional projections of grant clusters showed two dominant axes: physics-biology and therapeutic-diagnostic. Therapeutic and physics clusters have grown faster over time than diagnostic and biology clusters. The three topics with largest funding increase were Imaging biomarkers, Informatics, and Radiopharmaceuticals, which all had a mean annual growth of >$218,000. The three topics with largest funding decrease were Cellular stress response, Advanced imaging hardware technology, and Improving performance of breast cancer computer-aided detection (CAD), which all had a mean decrease of >$110,000.
    CONCLUSION: We developed a semi-automated NLP approach to analyze research topics and funding trends. We applied this approach to NCI funding in the radiological sciences to extract both domains of research being funded and temporal trends.
    Keywords:  clustering; funding trends; machine learning; natural language processing; research funding; topic modeling
    DOI:  https://doi.org/10.1016/j.ijrobp.2025.01.009
  99. Int J Biol Macromol. 2025 Jan 24. pii: S0141-8130(25)00850-5. [Epub ahead of print] 140301
    Emerging trends and innovations in polysaccharide-derived EMI shielding materials: A comprehensive review of bibliometric and performance analysis.
    Gerald Hendrik Tamuntuan, Ardiansyah Ardiansyah, Hanny Frans Sangian, Dolfie P Pandara, Darmawati Darwis, Dahlang Tahir.
      The increasing reliance on electronic devices has created a pressing demand for high-performance and sustainable electromagnetic interference shielding materials. While conventional materials, such as metals and carbon-based composites, offer excellent shielding capabilities, they are hindered by high costs, environmental concerns, and limitations in scalability. Polysaccharide-based materials, including cellulose, chitosan, and alginate, represent a promising alternative due to their biodegradability, renewability, and versatility. These materials, when combined with advanced fillers such as MXene, graphene, silver nanowires (AgNW), carbon nanotubes (CNTs), and magnetic nanoparticles like Fe3O4, exhibit exceptional shielding performance, often exceeding 100 dB, alongside lightweight and flexible characteristics. A detailed bibliometric analysis reveals a rapid growth in global research, with China leading in publication output and international collaborations. Advances in composite design, such as multilayered, gradient, and hybrid architectures, have significantly enhanced the functional capabilities of these materials, including improved absorption-reflection mechanisms, thermal management, and mechanical robustness. Despite these achievements, key challenges persist in optimizing filler dispersion, balancing electrical and mechanical properties, and developing scalable production methods. This review offers critical insights into the untapped potential of underexplored polysaccharides, such as starch and gums, and highlights their suitability for next-generation EMI shielding applications. By exploring the synergy between various fillers and polysaccharide matrices, the article outlines transformative pathways for creating high-performance, sustainable materials. Readers are equipped with actionable perspectives on innovative composite designs, material optimization strategies, and scalable fabrication techniques to address the evolving demands of advanced electronics and environmental sustainability.
    Keywords:  Bibliometric analysis; EMI shielding; Polysaccharide
    DOI:  https://doi.org/10.1016/j.ijbiomac.2025.140301
  100. Ann Surg. 2025 Jan 31.
    International Medical Graduates in Academic Cardiothoracic Surgery.
    Simar S Bajaj, Hanjay Wang, Kiah M Williams, Jack H Boyd.
       OBJECTIVE: To assess the research productivity, career advancement, grant funding, and scholarly impact of international medical graduates (IMGs) in academic cardiothoracic surgery.
    SUMMARY BACKGROUND DATA: Physician shortages undermine patient care and risk exacerbating inequities, especially in cardiothoracic surgery, which may lose a quarter of its workforce by 2050-the most substantial reduction in surgery. IMGs could help alleviate these shortages, but there is limited data about their academic experiences.
    METHODS: All cardiothoracic surgeons (n=1065) at accredited United States cardiothoracic surgery training centers in 2020 were included. IMGs were defined as surgeons who completed medical school outside the US and Canada, per the Association of American Medical Colleges. Educational and professional backgrounds were recorded from publicly available sources.
    RESULTS: 24.0% of academic cardiothoracic surgeons were IMGs. These surgeons started as attendings in later years (2012 vs. 2005, P<0.001) than non-IMGs. In unadjusted analyses, IMGs had lower publication counts and H-index, as well as reduced likelihood of R01 funding and full professor attainment. To match for attending start year, propensity score analysis created two groups of 254 surgeons: both IMGs and non-IMGs had similar publication counts (45.0 vs. 45.0, P=0.98), H-index (10.5 vs. 11.0, P=0.61), R01 funding rates (4.3% vs. 5.1%, P=0.83), and full professor attainment (24.8% vs. 20.5%, P=0.45).
    CONCLUSIONS: IMGs represent a more junior cohort of surgeons but contribute significantly to the cardiothoracic surgery workforce, with comparable academic success. Policy efforts to streamline IMGs' path toward US practice could help alleviate surgical shortages, while enhancing diversity and strengthening academia.
    DOI:  https://doi.org/10.1097/SLA.0000000000006646
  101. Sci Data. 2025 Jan 29. 12(1): 172
    A Multidisciplinary Multimodal Aligned Dataset for Academic Data Processing.
    Haitao Song, Hongyi Xu, Zikai Wang, Yifan Wang, Jiajia Li.
      Academic data processing is crucial in scientometrics and bibliometrics, such as research trending analysis and citation recommendation. Existing datasets in this domain have predominantly concentrated on textual data, overlooking the importance of visual elements. To bridge this gap, we introduce a multidisciplinary multimodal aligned dataset (MMAD) specifically designed for academic data processing. This dataset encompasses over 1.1 million peer-reviewed scholarly articles, enhanced with metadata and visuals that are aligned with the text. We assess the representativeness of MMAD by comparing its country/region distribution against benchmarks from SCImago. Furthermore, we propose an innovative quality validation method for MMAD, leveraging Language Model-based techniques. Utilizing carefully crafted prompts, this approach enhances multimodal processing capabilities to evaluate the accuracy of text-to-visual alignments. We also outline prospective applications for MMAD, providing the way for novel research endeavors, including automated caption generation and analysis of trends in figures. Thus, this work signals new research prospects and provides a fertile ground for advances in academic data processing.
    DOI:  https://doi.org/10.1038/s41597-025-04415-z
  102. J Gen Intern Med. 2025 Jan 27.
    Responding to: Rethinking Leadership in Academic Medicine: Embracing a Broader Definition of Success : Original article: Sticky Floor, Broken Ladder, and Glass Ceiling in Internal Medicine Academic Ranking, Leadership, and Research Productivity.
    Ali Khatib, Sonali Sharma, Aakar Chatha, Faisal Khosa.
      
    DOI:  https://doi.org/10.1007/s11606-025-09389-7
  103. Eur J Vasc Endovasc Surg. 2025 Jan 24. pii: S1078-5884(25)00105-4. [Epub ahead of print]
    Gender Representation Among Speakers and Chairs at the European Society for Vascular Surgery Annual Meetings.
    Jana Hammoud, Jennifer Canonge, Slaomé Kuntz, Justine Mougin, Marine Bordet, Jean N Sénémaud.
      
    Keywords:  Academic path; ESVS; Gender equity; Gender gap; Gender representation; Vascular surgery
    DOI:  https://doi.org/10.1016/j.ejvs.2025.01.034
  104. Mar Pollut Bull. 2025 Jan 28. pii: S0025-326X(25)00079-7. [Epub ahead of print]212 117604
    A bibliometric review on ghost fishing: Impacts on marine environment and governing measures.
    Suhas Wasave, Sushil Kamble, Tousif Kazi, Sangita Wasave, Sreekanth G B, Arpita Sharma.
      Ghost fishing, the phenomenon of abandoned, lost, or discarded fishing gear (ALDFG) that continues to trap and kill marine life, represents a significant environmental and economic threat to marine ecosystems and fisheries worldwide. This review aims to provide a comprehensive understanding of ghost fishing, examining its direct and indirect impacts on the marine environment and exploring the strategies employed to mitigate its effects. A total of 627 records from academic journals, government publications, research articles, and relevant online databases were screened using approved search engines. Following PRISMA guidelines, 87 documents were selected for meta-analysis. The results highlight the wide-ranging consequences of ghost fishing, including biodiversity loss, habitat destruction, economic losses, environmental degradation, and threats to fishery sustainability. Additionally, this paper reviews current efforts to reduce ghost fishing, including the development of sustainable fishing practices and policy interventions. By synthesizing the existing literature, policy documents, and community-based initiatives, this review aims to raise awareness of ghost fishing, enhance understanding of its ecological and economic impacts, and promote conservation efforts aimed at protecting marine ecosystems through more responsible fishing practices.
    Keywords:  Bibliometric; Ecosystem; Ghost fishing; Impacts; Marine; Mitigation measures
    DOI:  https://doi.org/10.1016/j.marpolbul.2025.117604
  105. Arch Osteoporos. 2025 Jan 28. 20(1): 13
    Bridging academia and public interest: the impact of Altmetrics on osteoporosis treatment research.
    Özge Özpolat Bulut, Bülent Alyanak, Burak Tayyip Dede, Mustafa Hüseyin Temel, Mustafa Turgut Yıldızgören, Fatih Bağcıer.
      
    DOI:  https://doi.org/10.1007/s11657-025-01500-z
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