bims-evares Biomed News
on Evaluation of research
Issue of 2024–12–01
83 papers selected by
Thomas Krichel, Open Library Society



  1. Int Dent J. 2024 Nov 22. pii: S0020-6539(24)01547-8. [Epub ahead of print]
       OBJECTIVE: Burning mouth syndrome (BMS) is a common oral pain disorder characterised by a burning sensation without any oral mucosal lesions. The etiopathogenesis of BMS remains unclear. A number of psychogenic and molecular mechanisms have been proposed to explain BMS; however, no bibliometric analyses have compiled the knowledge of BMS. Thus, this study aimed to explore the BMS research hotspots and trends from a bibliometric analysis perspective.
    METHODS: A comprehensive search related to BMS publications within the Web of Science Core Collection database was conducted. CiteSpace and VOSviewer software were used to analyse the bibliometric characteristics of the BMS research from January 2003 to September 2023, visualising the country distribution; author and co-cited authors; journals and co-cited journals; references and co-cited references; keyword cluster analysis; and timelines. We also reviewed related articles to provide references for integrating research frameworks.
    RESULTS: A total of 1080 BMS articles were published in 466 journals, with 34121 citations from 1447 institutions in 75 countries. The USA has made significant contributions to this field, with Nihon University (Japan) and the Mayo Clinic (USA) publishing the most articles. Toyofuku Akira is the most active author. Oral Diseases is regarded as the most productive journal. The top 3 co-citation clusters were cytokines, chronic pain, and therapy. According to the keyword burst analysis, the strongest keywords include stomatodynia, symptoms, and anxiety.
    CONCLUSION: Over the last 2 decades, the number of BMS publications has gradually and significantly increased worldwide. In recent years, research in the field of BMS has focused on studying the cellular and molecular underpinnings. A bibliometric analysis helps develop a better understanding of the pathogenesis of BMS and innovate more targeted therapeutic interventions in this field.
    Keywords:  Bibliometric analysis; Burning mouth syndrome; CiteSpace; Neurological factors; Therapy
    DOI:  https://doi.org/10.1016/j.identj.2024.09.034
  2. Med Oral Patol Oral Cir Bucal. 2024 Nov 25. pii: 26845. [Epub ahead of print]
       BACKGROUND: This study aimed to identify and analyze the most influential Mouth Breathing (MB) articles in children and adolescents with the highest relative citation rates (RCRs), through bibliometric and altmetric analysis, from 2002 to 2021.
    MATERIAL AND METHODS: On March 27, 2023 a PubMed search was conducted to detect papers published about MB. From a total of 826 documents, the article data were downloaded from iCite database. The 100 articles with the highest RCRs were selected for analysis in terms of RCR, citations, altmetric attention score, year, journal, first author (name, institution, country), subfield and design of study. The key words were analyzed using Vosviewer.
    RESULTS: Among the 100 articles, there were no differences between the two periods analyzed for RCR and AAS values, yet 2002-11 was more cited than 2012-2021. There was no correlation between RCR and AAS; but there was with citations. Brazil was the most cited country (n=30). The articles were published in 48 journals pertaining to 8 categories, 44 corresponding to Dentistry. The most frequent study design was the cross-sectional (n=48). Although all subfields were well represented, the most frequent ones were "treatment", "sleep disorders" and "clinical characteristics/cephalometry". The most prominent keywords were "malocclusion" and "cephalometry".
    CONCLUSIONS: Using RCR, a time- and field-normalized metric, one can identify influential articles in MB, a multidisciplinary research field of great importance for orthodontics. Because this bibliometric approach reduces the time from publication to the detection of an article´s importance for readers, it could be a valid alternative to using citation counts.
    DOI:  https://doi.org/10.4317/medoral.26845
  3. Dermatol Reports. 2024 Sep 02. 16(3): 9886
      A substantial body of literature has been published on acne vulgaris (AV) in the past five decades. Bibliometric analysis (BA) is a scientific, statistical evaluation review of published articles, providing a quantitative assessment of past research. The Web of Science (webOS) citation indexing database was used on 11 June 2023 to identify the top 100 cited articles on AV. Articles were listed in descending order by their annual citation (AC). Data sets were then subdivided into senior author, year and age of publication, journal and its impact factor, the number of total citations according to the webOS, corresponding and senior author's affiliated institution, country of origin, manuscript type, study design, and research focus. The top 100 most cited articles were published between 1974 and 2020. The mean number of citations ranges between 82 and 688. The most cited paper was Guidelines of care for the management of Acne Vulgaris by Zaenglein, with an AC of 98.2. The largest number of manuscripts was published between 2001 and 2010 (n = 47). The British Journal of Dermatology had the highest number of published manuscripts (15). Of the original research papers, 28% were of a level of evidence 1, 56% focused on treatment, 19.5% on epidemiology, and 16.5% on pathogenesis. This analysis provides detailed bibliometric characteristics, highlighting the worldwide acne burden, with the hope that future researchers will explore the gaps in the AV literature.
    Keywords:  acne vulgaris; bibliometric analysis; citation
    DOI:  https://doi.org/10.4081/dr.2024.9886
  4. Matern Child Health J. 2024 Nov 25.
       OBJECTIVE: This systematic review and bibliometric analysis investigated the keywords appearing most in the pregnancy-related eye disease field to elucidate the current state and trends of pregnancy-related eye disease research.
    METHODS: A systematic literature analysis of pregnancy-related eye disease was performed using the Web of Science Core Collection (WOS) databases. We used the keywords "ocular" OR "eye*" and "pregnancy" OR "pregnant" OR "gestation" to search for articles published from 1999 to 2022. Study data were analyzed and visualized using VOSviewer and CiteSpace.
    RESULTS: We analyzed 929 articles published from 1999 to 2022. From 1999 to 2012, the article number increased slowly, with a marked acceleration in publication frequency after 2013, original papers accounted for 780 (84%) of the total number of articles published. David A. Mackey was the most prolific writer, and Margaret A. Honein contributed the most citations. The American Journal of Ophthalmology, PLOS One, and the European Journal of Ophthalmology published the most articles. The American Journal of Ophthalmology, Ophthalmology, British Journal of Ophthalmology, Investigative Ophthalmology and Visual Science were the four most commonly cited journals. The University of Western Australia, the University of Sao Paulo, and the University of Melbourne were highly prolific institutions. Five co-cited references had a citation burst up to 2022, analyzed by CiteSpace. Keyword analysis (VOSviewer) yielded recent key themes (pregnancy, women, eye, risks and diagnosis) and suggested future research directions.
    CONCLUSIONS: The current results laid the foundation of bibliometrics for scholars and identified researchers, scientific journals, countries, keyword clustering, hot topics, and trends in the literature. High-impact-factor journals contain the most keyword-clustering research and open new horizons for research in the pregnancy-related eye disease nursing field, providing research inspiration for investigators in this field.
    Keywords:  Bibliometrics; CiteSpace; Pregnancy-related eye disease; VOSviewer
    DOI:  https://doi.org/10.1007/s10995-024-04017-y
  5. Front Immunol. 2024 ;15 1497461
       Background: Metabolic reprogramming (MR) in cancer (CA) has been a focus of intense research in the recent two decades. This phenomenon has attracted great interest because it offers potential targets for cancer therapy. To capture the intellectual landscape of this field, we conducted a bibliometric analysis to assess the scientific output, major contributors, and trends in the MR/CA research.
    Methods: We performed a systematic search using the Web of Science to retrieve articles published on MR of cancer from 2006 until 2023. The bibliometric tools such as Biblioshiny, VOSviewer, and Microsoft Excel were used to identify the most prolific authors, institutions, citation patterns, and keywords. We also used co-citation analysis to map the conceptual structure of the field and identify influential publications. Furthermore, we examined the literature by analyzing publication years, citations, and research impact factors.
    Results: A total of 4,465 publications about MR/CA were retrieved. Publications on MR/CA increased rapidly from 2006 to 2023. Frontiers in Oncology published the most papers, while Cell Metabolism had the most citations. Highly cited papers were mainly published in Cancer Cell, Nature, Cell, Science and Cell Metabolism. China and the United States led the way in publications and contributed the most to MR/CA research. The University of Texas System, Chinese Academy of Sciences, and Fudan University were the most productive institutions. The profitable authors were Deberardinis Ralph J and Chiarugi Paola. The current topics included MR in tumorigenesis and progression of CA, MR of tumor cells and tumor microenvironment, the effect of MR on the CA treatment, the underlying mechanisms of MR (such as gene regulation, epigenetics, extracellular vesicles, and gut microbiota), and the modulation of MR. Some topics such as tumor microenvironment, lipid MR, circular RNA, long noncoding RNA, exosome, prognostic model, and immunotherapy may be the focus of MR/CA research in the next few years.
    Conclusion: This study evaluated the global scientific output in the field of MR/CA research, analyzing its quantitative characteristics. It identified some significant and distinguished papers and compiled information regarding the current status and evolving trends of MR/CA research.
    Keywords:  bibliometrics; cancer; high-cited papers; hotspots; metabolic reprogramming; scientometrics
    DOI:  https://doi.org/10.3389/fimmu.2024.1497461
  6. J Multidiscip Healthc. 2024 ;17 5407-5423
       Objective: This study aimed to examine the global scientific output of research on patient delay and explore the hotspots and frontiers from 2000 to 2023 through bibliometric analysis.
    Methods: Publications regarding patient delay published from 2000 to 2023 were extracted from the Web of Science Core Collection (WOSCC). Subsequently, CiteSpace, VOSviewer, and Bibliometrix Online Analysis Platform were used to analyze publications, countries, institutions, authors, journals, and keywords.
    Results: A total of 721 papers were included in the study. The publication output increased from 20 papers in 2000 to 64 papers in 2023, a remarkable 220.00% growth. The USA (138 papers) and University of California San Francisco (21 papers) were identified as the most productive country and institution, respectively. Moser (10 papers), and Dracup (10 papers) are the most productive authors. "BMC Public Health" (24 publications) is the most productive journal. "Patient Delay" was the most cited keyword, with high-frequency keywords such as "Prehospital Delay", "Symptoms", "Time", "Care", "Diagnosis", "Acute Myocardial-infarction", and "Mortality" signaling hot topics in Patient Delay.
    Conclusion: There are increasingly many papers on patient delay. However, there has been limited development of cooperation between countries and institutions. In the future, collaboration between countries and institutions should be strengthened. In addition, 3 hotspots and 3 frontiers are summarized in this study to provide researchers with future research directions.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; frontiers; hotspots; patient delay; web of science
    DOI:  https://doi.org/10.2147/JMDH.S495024
  7. Pathogens. 2024 Nov 14. pii: 996. [Epub ahead of print]13(11):
      The lung microbiome has emerged as a pivotal area of research in human health. Despite the increasing number of publications, there is a lack of research that comprehensively and objectively presents the current status of lung microbiome-related studies. Thus, this study aims to address this gap by examining over two decades of publications through bibliometric analysis. The original bibliographic data of this study were obtained from the Web of Science Core Collection, focusing on publications from 2003 to 2023. The analysis included the data extraction and examination of authors, affiliations, countries, institutions, abstracts, keywords, references, publication dates, journals, citations, H-indexes, and journal impact factors. A total of 845 publications were identified, showing an increasing trend in both publications and citations over the years, particularly in the last decade. The analysis highlighted the most productive authors, institutions, and countries/regions, and identified potential partners for interested researchers. Co-citation analysis revealed that lung microbiome- and infectious/pulmonary disease-related studies are at the forefront of the field. The hotspots and frontiers of the lung microbiome field have progressed from basic composition to exploring specific mechanisms and the clinical value of diseases. In conclusion, this study provides a comprehensive overview of the current research status and trends in the field of the lung microbiome over the past two decades and highlights the areas that need more attention and research efforts. It offers valuable insights for researchers and institutions and identifies key hotspots and frontiers, which can serve as references for related researchers and future research.
    Keywords:  CiteSpace; bibliometrics; lung; microbiome; visualization
    DOI:  https://doi.org/10.3390/pathogens13110996
  8. Clin Cardiol. 2024 Dec;47(12): e70051
       OBJECTIVES: To perform a bibliometric analysis of publications of arrhythmogenic right ventricular cardiomyopathy (ARVC) from 1981 to 2023 to summarize the current publications and explore frontiers on this topic.
    METHODS: We integrated the scientific publications on ARVC in the Web of Science (WOS) Core Collection database from January 1981 to September 2023, using the retrieval strategy of medical subject headings combined with keywords. We focused on articles and reviews that were published in English. Relevant information such as the journal and publisher, the title, authors, organizations, abstract, keywords, published date, and number of citations, were collected. Bibliometric analysis was performed and visualized by the R software and Microsoft Excel.
    RESULTS: The results revealed a total of 4792 records related to ARVC from the WOS database, and 2992 original articles or reviews which were selected for bibliometric analysis. There were 79 countries and regions, 3724 research institutions, and 12 157 scholars who have published in this topic. The number of scientific publications of ARVC increased year-by-year, with an annual growth rate of 12.12%. We also investigated the top 10 contributing countries, organizations with affiliations, most influential researchers, highest-cited articles, and highest-frequency keywords. In addition, the most active areas of research on ARVC included that of fatal complications, molecular pathological mechanisms, diagnosis, therapy, and prognosis respectively according to the keywords trend analysis.
    CONCLUSIONS: Our study reports the publication landscape of ARVC during the past four decades based on bibliometric analysis. This study provides a deeper understanding of the published literature on ARVC.
    Keywords:  arrhythmogenic right ventricular cardiomyopathy; bibliometric analysis; diagnosis; fatal complications; molecular mechanism; prognosis; therapy
    DOI:  https://doi.org/10.1002/clc.70051
  9. Neurol Res. 2024 Nov 27. 1-12
       BACKGROUND: Cerebral venous sinus thrombosis (CVST) is an uncommon form of cerebrovascular disease. Although our understanding of CVST has improved significantly over the past decades, there has been no bibliometric analysis of CVST until now. We aimed to examine and visualize the hotspots and trends of the research related to CVST using a bibliometric analysis based on Citespace and provide new insights for scholars in their future researches in this area.
    METHODS: The literature on CVST was collected from the Web of Science Core Collection database. Bibliometric analysis was performed using CiteSpace (6.2.R3) Advanced software.
    RESULTS: A total of 2396 articles were included in the analysis. Publications regarding CVST have increased over time. U.S.A. contributed the most articles. Ferro JM had the highest number of published papers. Stroke was the journal with the most publications and the most commonly cited journal. Nine out of the top 10 cited journals belong to Q1. The risk factors for CVST, emerging and current treatment of CVST, and CVST related to COVID-19 and COVID-19 vaccines are the major potential research hot spots and trends.
    CONCLUSIONS: CVST is a rapidly expanding research area and has received increasing attention by the researchers. Our study can provide researchers valuable information on the current status and trends in this area and guide for future studies.
    Keywords:  Cerebral venous sinus thrombosis (CVST); CiteSpace; bibliometric analysis; cerebrovascular disease; venous sinus thrombosis
    DOI:  https://doi.org/10.1080/01616412.2024.2430999
  10. Clin Dermatol. 2024 Nov 26. pii: S0738-081X(24)00257-8. [Epub ahead of print]
      This study provides a comprehensive bibliometric analysis of Prurigo Nodularis (PN) literature, identifying influential studies, key contributors, and emerging trends to understand the evolution of research and guide future investigations. A total of 499 papers published between 1951 and October 2024, containing the term Prurigo Nodularis in their abstracts, were analyzed. Keyword analysis was conducted to determine the main themes across these publications. Additionally, the top 100 most cited PN papers from 1979 to 2023 were examined, involving 51 journals and sources. Metrics such as mean total citations per article (MeanTCperArt) and mean total citations per year (MeanTCperYear) were calculated for these top 100 papers. The analysis of the top 100 most cited papers revealed contributions from 453 authors. The number of publications, citations, h-index, g-index, m-index, HG composite, and Q2 index were calculated for each. We have illustrated the dynamics of top authors, universities, and countries, as well as their respective collaboration networks. The thematic evolution of PN research was assessed using co-word analysis, followed by a systematic discussion of the findings. This bibliometric analysis provides a comprehensive overview of the key contributors and research trends in PN literature, offering valuable insights for guiding future investigations.
    Keywords:  Prurigo Nodularis; bibliometric analysis; citation analysis; co-words analysis; collaboration networks; most cited papers; research trends; thematic evolution
    DOI:  https://doi.org/10.1016/j.clindermatol.2024.11.004
  11. Curr Probl Diagn Radiol. 2025 Jan-Feb;54(1):pii: S0363-0188(24)00204-4. [Epub ahead of print]54(1): 87-91
       INTRODUCTION: This study explores the evolution of authorship dynamics in Interventional Radiology over a fifteen-year period, with a focus on gender disparities. It aims to illuminate the representation of female authors in high-impact IR journals, highlighting ongoing challenges in achieving gender diversity, especially in leadership roles.
    METHODS: A bibliometric analysis was conducted on articles published from 2008 to 2023, systematically assessing trends in female first and last authorships, as well as their overall contribution to total authorship within prominent IR journals.
    RESULTS: The analysis revealed a fluctuating trajectory in female authorship. Female first authorship peaked in 2011, followed by a decline through 2012-2013, and subsequently rebounded by 2023. Female last authorship exhibited a similar non-linear pattern, with an initial decline from 2008 to 2013, before gradually increasing in recent years. Overall, the presence of female authors in IR publications has steadily grown, with a notable rise in the proportion of publications featuring female authors and an increase in the average number of female contributors per article by 2023.
    CONCLUSION: Despite the overall growth in female authorship, significant disparities persist, particularly in senior authorship positions. These findings highlight the need for sustained efforts to address gender inequities in IR, emphasizing the importance of robust policies and support systems to promote women's advancement within the field.
    Keywords:  Academic productivity; Authorship trends; Bias in academia; COVID-19 impact; Citation impact; Collaborative authorship; Diversity in research; Female leadership; Gender disparities; Gender equity; IR gender gap; Inclusive authorship; Mentorship gaps; Publishing trends; Senior authorship; Structural barriers; Women in IR
    DOI:  https://doi.org/10.1067/j.cpradiol.2024.10.032
  12. Acta Obstet Gynecol Scand. 2024 Nov 23.
       INTRODUCTION: Some women are unable to become pregnant because they do not have a functional uterus. Over the last decade, it has become possible for these women to get pregnant through uterus transplantation, which has been the subject of numerous research studies. Therefore, the purpose of this study is to review published articles in the uterus transplantation area.
    MATERIAL AND METHODS: We conducted a cross-sectional bibliometric review to study the 100 highly cited papers in the Web of Science and Scopus databases from 1960 to 2024. Our research applied bibliometric analysis to these top 100 highly cited papers. Document citation and co-occurrence analysis were used for the data study. VOSviewer along with Bibliometrix® software was used to design the maps.
    RESULTS: The trend of uterus transplantation publications increased exponentially after 2010. Sweden is the leading country, followed by the USA and Spain. Fertility and Sterility, Lancet, American Journal of Transplantation, and Human Reproduction were the highly cited journals. Collaboration among countries showed that the most collaboration took place between Sweden and Spain (18), Sweden and the USA (14), the USA and Spain (8), Sweden and Australia (6), and the USA and the United Kingdom (6). Furthermore, the results found that more than one-third of the highly cited papers were review papers (39%) and 27% were clinical trial studies.
    CONCLUSIONS: This bibliometric review provides a valuable contribution to the literature on uterine transplantation by synthesizing and analyzing existing research findings. It offers insights into current trends, key themes, geographic distribution, and potential areas for future research within this rapidly evolving field.
    Keywords:  Scopus database; Web of Science database; bibliometric; co‐occurrence analysis; highly cited; uterus transplantation
    DOI:  https://doi.org/10.1111/aogs.14977
  13. Bioengineering (Basel). 2024 Oct 24. pii: 1063. [Epub ahead of print]11(11):
      The relationship between gut microbiota and glaucoma has garnered significant interest, with emerging evidence suggesting that gut dysbiosis, inflammation, and immune mechanisms may contribute to glaucoma pathogenesis. Understanding these interactions through the gut-retina axis offers new insights into disease progression and potential therapeutic options. This study combines bibliometric analysis and literature review to evaluate research trends and key research areas related to gut microbiota's role in glaucoma. Our data were collected from the Web of Science Core Collection (WoSCC) and included the English original articles and reviews published between 1 January 2008, and 6 August 2024. Visual and statistical analyses were conducted using VOSviewer and CiteSpace. The analyses comprised 810 citations from leading journals, representing contributions from 23 countries/regions, 111 institutions, 40 journals, and 321 authors. Among the countries and regions involved, the USA and China were the leading contributors, publishing the most articles and being major research hubs. The Experimental Eye Research and Investigative Ophthalmology & Visual Science were the top journals in citation and co-citations that produced high-quality publications. The top 10 highly cited articles were published in high-ranking, top-quartile journals. The frequently occurring keywords were "glaucoma", "microbiota", "gut microbiota", "inflammation", "gut-retina axis", and "probiotics". Our study highlights the growing interest in the association between gut microbiota and glaucoma. It summarizes the possible ways gut microbiota dysbiosis, systemic and neuroinflammation, and autoimmune mechanisms contribute to glaucomatous pathogenesis. Future research should focus on mechanistic studies to elucidate the pathways linking gut microbiota to glaucoma development and progression.
    Keywords:  bibliometric analysis; glaucoma; gut microbiota; gut-retina axis; inflammation; microbiota dysbiosis
    DOI:  https://doi.org/10.3390/bioengineering11111063
  14. Clin Cosmet Investig Dermatol. 2024 ;17 2595-2613
       Aim: The application of bibliometric analysis gives insights into research trend and future perspectives. This paper aims to understand the current status of studies on traditional Chinese medicine (TCM) in the treatment of atopic dermatitis (AD), and to investigate the cooperation network, hotspots and trends in the field.
    Methods: The original data were retrieved from the Web of Science Core Collection by searching for the topic "atopic dermatitis" and "traditional Chinese medicine" with the time span of 2004-2023. Microsoft Excel was used to create statistical tables and charts, whereas CiteSpace and VOSViewer were applied for knowledge mapping.
    Results: In total, 252 publications were identified and downloaded. Current research on TCM treating AD is in the steady growth period. China has the largest number of publications, whereas the USA has the greatest international influence. Notably, the Arab Emirates, Malaysia, India and Bangladesh all have a high research impact but with a low amount of publications. Universities in Hong Kong China have the largest number of publications, but their interaction with other institutions is very poor. The top three most productive authors are all from Hong Kong, having a strong collaboration network with each other. The popular research topics in this field are "children" "cell" "activation" "nf kappa b" "inflammation" "asthma" "extract" "management" and "cytokine". According to the analysis of leading co-cited journals and authors, "J ETHNOPHARMACOL" has the largest amount of citations whilst "AM J CHINESE MED" the strongest academic influence. The largest number of co-cited authors comes from "Hon Karn-Lun Ellis", a well-known scholar from Hong Kong.
    Conclusion: TCM has been widely used in AD treatment, honored for its individualized therapeutic concepts of evidence-based treatment. The academic community must form a continuous and deep-going pattern to achieve higher international influence and a stronger research degree in this field.
    Keywords:  atopic dermatitis; bibliometrics; knowledge mapping; traditional Chinese medicine; visual analysis
    DOI:  https://doi.org/10.2147/CCID.S479632
  15. Front Med (Lausanne). 2024 ;11 1510463
       Background: The association between the gut microbiota and sepsis has garnered attention in the field of intestinal research in sepsis. This study utilizes bibliometric methods to visualize and analyze the literature on gut microbiota research in sepsis from 2011 to 2024, providing a scientific foundation for research directions and key issues in this domain.
    Methods: Original articles and reviews of gut microbiota research in sepsis, which published in English between 2011 and 2024, were obtained from the Web of Science Core Collection on June 21, 2024. Python, VOSviewer, and CiteSpace software were used for the visual analysis of the retrieved data.
    Results: A total of 1,031 articles were analyzed, originating from 72 countries or regions, 1,614 research institutions, and 6,541 authors. The articles were published in 434 different journals, covering 89 different research fields. The number of publications and citations in this research area showed a significant growth trend from 2011 to 2024, with China, the United States, and the United Kingdom being the main research forces. Asada Leelahavanichkul from Thailand was identified as the most prolific author, making him the most authoritative expert in this field. "Nutrients" had the highest number of publications, while "Frontiers in Cellular and Infection Microbiology," "Frontiers in Immunology" and "the International Journal of Molecular Sciences" have shown increasing attention to this field in the past 2 years. Author keywords appearing more than 100 times included "gut microbiota (GM)," "sepsis" and "microbiota." Finally, this study identified "lipopolysaccharides (LPS)," "short-chain fatty acids (SCFAs)," "probiotics," "fecal microbiota transplantation (FMT)" and "gut-liver axis" as the research hotspots and potential frontier directions in this field.
    Conclusion: This bibliometric study summarizes current important perspectives and offers comprehensive guidance between sepsis and intestinal microbiota, which may help researchers choose the most appropriate research directions.
    Keywords:  CiteSpace; VOSviewer; bibliometric; intestinal microbiota; sepsis
    DOI:  https://doi.org/10.3389/fmed.2024.1510463
  16. Int Urol Nephrol. 2024 Nov 26.
       BACKGROUND: There is a lack of bibliometric analysis in research regarding primary therapy for end-stage renal disease (ESRD). This study aims to analyze the literature on ESRD therapy published over the past decade to understand current conditions and study trends for future research.
    METHODS: Data were collected from the Web of Science Core Collection (WOSCC) database. Tools like CiteSpace 6.2.R4, 6.1.R6, VOSviewer 1.6.18, and Bibliometrix R4.1.1 were used to reveal research trends and hotspots. In addition, KEGG/GO analysis examined the probable functionalities of genes implicated in ESRD therapy to guide future research.
    RESULTS: The bibliometric analysis presented in this paper indicates that the number of publications has remained relatively stable since 2013. The level of international collaboration is notably high, with the United States serving as the dominant research hub in this field. The University of California system is the most prolific institution, and Transplantation Proceedings is the most frequently published journal in this area. Kalantar-Zadeh, Kamyar is recognized as the most published and cited author. Keywords such as "secondary hyperparathyroidism," "uremic toxins," "cyclosporine," "mycophenolate mofetil," and "biomarkers" have seen a surge in interest recently, reflecting emerging research trends. Furthermore, inflammation and stem cell research have been identified as promising new therapeutic avenues for ESRD.
    CONCLUSION: This study identifies major areas, frontiers, and trends in research on primary treatments for ESRD, providing significant implications for future research.
    Keywords:  Bibliometric analysis; End-stage renal disease; Renal replacement therapy; Research hotspots; Research trends
    DOI:  https://doi.org/10.1007/s11255-024-04290-4
  17. J Multidiscip Healthc. 2024 ;17 5473-5486
       Purpose: Colorectal cancer (CRC) is among the most prevalent malignancies worldwide, with rising incidence and mortality rates presenting substantial public health challenges. Traditional detection methods have inherent limitations, which has led to growing interest in liquid biopsy technologies for the identification of circulating tumor DNA (ctDNA). The aim of this study is to explore the developmental trends and future prospects of ctDNA in colorectal cancer through bibliometric analysis.
    Methods: This bibliometric analysis examines the literature on ctDNA in CRC from 2004 to 2024, utilizing the Web of Science Core Collection database to identify research trends, key areas of interest, and potential future directions. The R package "bibliometrix" and VOSviewer software were employed for bibliometric analysis and visualization. The analysis encompassed an evaluation of publication volume, contributing authors, influential journals, country and institutional contributions, and citation metrics.
    Results: The analysis encompassed a total of 1,054 publications, demonstrating a marked escalation in research activity since 2015. The journal "Cancers" has been identified as the most prolific publisher within this domain. Prominent researchers, including Bardelli A and Sartore-Bianchi A, have made substantial contributions to the field. The United States is the leading country in terms of both publication volume and citation frequency, followed by China and Italy. A keyword analysis identified seven conceptual clusters, with "circulating tumor DNA" and "liquid biopsy" emerging as predominant themes.
    Conclusion: This study emphasizes the evolving emphasis on the clinical applications of ctDNA, encompassing early detection, treatment monitoring, and prognostic assessment in CRC, thereby underscoring its potential as a non-invasive biomarker in oncology.
    Keywords:  bibliometric analysis; circulating tumor DNA; colorectal cancer
    DOI:  https://doi.org/10.2147/JMDH.S493863
  18. J Infect Public Health. 2024 Nov 22. pii: S1876-0341(24)00331-9. [Epub ahead of print]18(1): 102597
       BACKGROUND: With an ever growing and expanding body of literature on the newly developed vaccines against the COVID-19, there is an urgent need for a comprehensive analysis of the current state of research on vaccine effectiveness (VE). This study conducted a comprehensive bibliometric analysis to critically examine the productivity and impact of retrieved publications on COVID-19 VE and to predict the future directions of research in the field.
    METHODS: The global literature on COVID-19 VE from 2021 to 2024 was extracted from the VIEW-hub website. Using bibliometric analysis tools, specifically Microsoft Excel, the R package "bibliometrix, biblioshiny" and VOSviewer, we analyzed publications for trends in productivity, citations, and global collaboration. Key metrics assessed include publication and citation trends, influential authors, collaborative networks, and thematic evolution, offering a comprehensive view of the research landscape on COVID-19 VE.
    RESULTS: A total of 490 publications were authored by 5031 authors from 934 institutions and 78 countries and published in 119 journals. Most retrieved publications were original articles (99.6 %). The United States was the most productive country with 205 publications (41.8 %). Global research collaborations were mainly within developed countries. Analysis of the thematic evolution of the field illustrated changing research focus over three distinct time clusters. Throughout 2021, studies were focused on outlining infection prevention and control measures, as well as examining the efficacy of novel mRNA vaccines. In 2022, the linchpin of research was shifted towards dissecting the epidemiological correlates of the pandemic in light of the widespread use of vaccines. The final cluster showed special emphasis on the new variants of COVID-19 and the long-term outcomes of vaccines.
    CONCLUSION: Our study identified geopolitical disparities and weak engagement from developing countries in the ongoing efforts regarding COVID-19 VE. This study can inform researchers, policymakers, and funding agencies as they assess ongoing research and future directions in COVID-19 VE.
    Keywords:  Bibliometrics; Biblioshiny; COVID-19; VOSviewer; Vaccine effectiveness
    DOI:  https://doi.org/10.1016/j.jiph.2024.102597
  19. Front Psychiatry. 2024 ;15 1457191
       Background: Non-suicidal self-injury(NSSI)is a widespread occurrence among adolescents, and this behavior can bring serious consequences. In recent years, the prevalence of NSSI continues to rise, which has attracted the attention of many researchers. But currently there is no research exploring the overall research distribution of NSSI in adolescents through quantitative analysis. Therefore, it is necessary to understand the status of development and main research hotspots of NSSI in adolescents via bibliometric analysis.
    Methods: We searched the relevant studies from the Web of Science Core Collection(WoSCC)from January 1, 2014 to December 31, 2023. Using CiteSpace and VOSviewer visual analysis tools, we analyzed studies from the perspectives of country, region, institution, journal, author, and keywords.
    Result: A total of 2177 studies related to NSSI in adolescents were included. USA and Harvard University were the leading country and institution in this research field. Penelope Hasking was the most prolific author. Frontiers in Psychiatry and the Journal of Affective Disorders were the most productive journals. The most high-frequency keywords were 'depression', 'mental health', 'emotion regulation' and 'borderline personality disorder'. 'mindfully', 'intervention', 'self-compassion' and 'ecological momentary assessment' were the emerging keywords.
    Conclusions: Exploring the relevant factors and mechanisms of comorbidities, identifying etiology and risk/protective factors, and finding the impact of NSSI on adolescents are the hot topics. Moreover, intervention measures and interdisciplinary collaborative research for NSSI in adolescents will emerge as frontiers in the future.
    Keywords:  NSSI; adolescent; bibliometrics; non-suicidal self-injury; visualization analysis
    DOI:  https://doi.org/10.3389/fpsyt.2024.1457191
  20. Front Cardiovasc Med. 2024 ;11 1448125
       Background: In recent years, the relationship between periodontal disease (PD) and atherosclerosis (AS) has garnered significant scholarly attention. Chronic inflammation induced by PD may promote the onset and progression of AS through multiple mechanisms. Given the increasing global incidence of both PD and AS, which adversely affects patients' quality of life and longevity, further investigation into the interplay between PD and AS is of substantial clinical importance. This study aims to conduct a comprehensive analysis of the association between PD and AS using bibliometric methods.
    Methods: Articles and reviews on the association between PD and AS were retrieved from the Web of Science Core Collection (WOSCC) on June 1, 2023. Bibliometric and knowledge mapping analyses were conducted using CiteSpace [6.3.R1 (64-bit) Advanced].
    Results: Through a bibliometric analysis of the literature published between 2000 and 2023 on the PD-AS relationship, we identified 1,572 relevant studies. The results show a steadily increasing number of studies on this topic annually, with a significant upward trend after 2002. Keyword analysis reveals "atherosclerosis," "periodontal disease," "cardiovascular disease," "Porphyromonas gingivalis," and "periodontal pathogens" as research hotspots. Collaboration network analysis highlights the United States as the primary contributor to research in this field. Co-citation analysis shows that J Periodontol, J Clin Periodontol, and Circulation are the most frequently cited journals, reflecting their support for research in this area. Document co-citation analysis identifies several high-impact studies focusing on how systemic inflammation induced by periodontitis promotes AS. This study uncovers development trends and research hotspots in the PD-AS relationship and emphasizes the role of international collaboration and high-impact journals in advancing this field. These insights provide valuable references and guidance for future research.
    Conclusion: PD and AS are global epidemics causing significant distress and imposing a substantial burden. Research on the PD-AS relationship is evolving rapidly and continues to be a critical focus. Elucidating the mechanisms linking PD and AS represents an emerging trend, providing valuable references for future studies.
    Keywords:  Porphyromonas gingivalis (P. gingivalis); atherosclerosis; bibliometrics; inflammation; mechanisms; periodontal disease (PD)
    DOI:  https://doi.org/10.3389/fcvm.2024.1448125
  21. Front Nutr. 2024 ;11 1496582
       Background: The prevalence of obesity and its related ailments is on the rise, posing a substantial challenge to public health. Tea, widely enjoyed for its flavors, has shown notable potential in mitigating obesity. Yet, there remains a lack of exhaustive bibliometric studies in this domain.
    Methods: We retrieved and analyzed multidimensional data concerning tea and obesity studies from January 2004 to June 2024, using the Web of Science Core Collection database. This bibliometric investigation utilized tools such as Bibliometrix, CiteSpace, and VOSviewer to gather and analyze data concerning geographical distribution, leading institutions, prolific authors, impactful journals, citation patterns, and prevalent keywords.
    Results: There has been a significant surge in publications relevant to this field within the last two decades. Notably, China, Hunan Agricultural University, and the journal Food and Function have emerged as leading contributors in terms of country, institution, and publication medium, respectively. Zhonghua Liu of Hunan Agricultural University has the distinction of most publications, whereas Joshua D. Lambert of The State University of New Jersey is the most cited author. Analyses of co-citations and frequently used keywords have identified critical focus areas within tea anti-obesity research. Current studies are primarily aimed at understanding the roles of tea components in regulating gut microbiota, boosting fat oxidation, and increasing metabolic rate. The research trajectory has progressed from preliminary mechanism studies and clinical trials to more sophisticated investigations into the mechanisms, particularly focusing on tea's regulatory effects on gut microbiota.
    Conclusion: This study offers an intricate overview of the prevailing conditions, principal focus areas, and developmental trends in the research of tea's role against obesity. It delivers a comprehensive summary and discourse on the recent progress in this field, emphasizing the study's core findings and pivotal insights. Highlighting tea's efficacy in obesity prevention and treatment, this study also points out the critical need for continued research in this area.
    Keywords:  bibliometric analysis; epigallocatechin gallate; gut microbiota; lipid metabolism; obesity; tea; tea polyphenols; tea polysaccharides
    DOI:  https://doi.org/10.3389/fnut.2024.1496582
  22. Clin Rheumatol. 2024 Nov 28.
       BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disorder, and a growing body of research has demonstrated the involvement and regulatory roles of microRNAs (miRNAs) in the pathogenesis of RA. Consequently, this study aims to evaluate the current status and emerging trends in miRNA research related to RA by employing bibliometric analyses from a comprehensive perspective.
    METHODS: Relevant literature pertaining to miRNA-related RA was systematically searched and screened from the Web of Science Core Collection (WOSCC) database, covering the period from January 1, 2010 to June 30, 2024. Subsequently, the data were subjected to visual analysis using CiteSpace, VOSviewer, the R package, and Bibliometric. This comprehensive approach aimed to elucidate the global state of research, as well as to identify prevailing trends and emerging hotspots within the field.
    RESULTS: A comprehensive analysis included 843 publications authored by 4451 researchers from 1096 institutions across 47 countries/regions, with relevant articles disseminated through 297 journals. China emerged as the leading contributor in terms of research output. Specifically, China Medical University and the researcher Chih-Hsin Tang were identified as the most influential institution and author, respectively. "Frontiers in Immunology" was recognized as the most prolific journal, whereas "Arthritis Research & Therapy" garnered the highest number of citations. Notably, Stanczyk's 2008 study published in "Arthritis & Rheumatism" received the highest citation count. Additionally, related research areas such as circular RNAs (circRNAs) and extracellular vesicles (EVs) have become new hotspots in the field.
    CONCLUSIONS: MiRNAs have garnered significant interest among researchers studying RA, as they show considerable potential for improving RA diagnosis and treatment. As research in this area advances, it is anticipated that scholars will allocate more resources to investigating circRNAs and EVs associated with miRNAs. This focus is expected to provide valuable insights for identifying novel therapeutic targets and drug delivery vectors for RA.
    Keywords:  Bibliometrics; Hotspots; MicroRNA; Rheumatoid arthritis; Visualization
    DOI:  https://doi.org/10.1007/s10067-024-07250-6
  23. Cardiorenal Med. 2024 Nov 23. 1-29
      Introduction This study endeavors to evaluate the distribution patterns and research frontiers within the international literature on the association between chronic kidney disease and cardiovascular diseases in the medical field, through bibliometric analysis and visualized information. Methods The Web of Science Core Collection database was selected as the data source from 2010 to 2023, and articles related to the association between chronic kidney disease and cardiovascular diseases were retrieved. The article data was analyzed through CiteSpace for bibliometric mapping, involving the examination of keywords, references, country/region distributions, and institutional contributions to identify and understand the evolving research dynamics and frontiers in this interdisciplinary field. Results A total of 2936 publications on the association between chronic kidney disease and cardiovascular diseases were included. The country with the most publications was USA (n=904), and the institution with the most publications was University of Pennsylvania (n=116). The most frequent keywords were chronic kidney disease (n=2194), cardiovascular disease (n=1188), and mortality (n=604). The top 20 keywords and top ten references that burst during 2010 to 2023 were listed. Conclusion The association between chronic kidney disease and cardiovascular diseases has sparked extensive research, particularly in high-prevalence areas. From 2010 to 2023, publications on the association between chronic kidney disease and cardiovascular diseases show a linear increase. Current research hotspots and frontiers are mainly in cardiovascular-kidney-metabolic syndrome; innovative therapies and drug impact; gut microbiome; mendelian randomization analysis. Overall, our study offers a comprehensive scientometric analysis of the association between chronic kidney disease and cardiovascular diseases, providing valuable insights for both researchers and healthcare professionals in the field.
    DOI:  https://doi.org/10.1159/000542441
  24. Clin Rheumatol. 2024 Nov 30.
       OBJECTIVE: To analyze the development status and trend of related research in the health management of hyperuricemia and provide a theoretical basis for clinical treatment.
    METHODS: A bibliometric analysis was conducted on hyperuricemia health management research data from 2000 to 2024 using the Web Science Core Collection database, PubMed, and SINOMED. A total of 789 articles were evaluated for specific characteristics, such as year of publication, journal, author, institution, country/region, reference, and keyword. The VOSviewer was used for co-author, co-occurrence, co-citation, and network visualization. Important sub-topics identified by bibliometric characteristics were discussed and reviewed.
    RESULTS: The number of articles published in the last 24 years has generally followed a year-on-year trend, and the total number of papers published is increasing. Over 200 affiliations from 70 countries and regions contributed papers, and PLOS ONE has the highest number of linked publications. Dalbeth N, is the author with the most publications, with an H-index of 17. Hyperuricemia, gout, management, prevalence, allopurinol, risk, and other keywords were often used. Researchers formed mature teams, and the teams' study directions intersect and are comparable. However, these teams demonstrated a lack of communication and coordination.
    CONCLUSIONS: This study highlights research hotspots, global cooperation models, and emerging frontiers in hyperuricemia, focusing on uric acid control, disease screening, health education, and epidemiological investigation in hyperuricemia-associated complications over the past two decades. However, there is still a lack of standardized management processes and systems, and the communication between research teams needs to be enhanced. Key Points • The study analyzed hyperuricemia health management research data from 2000 to 2024 using the Web Science Core Collection database, PubMed, and SINOMED, evaluating 789 articles and discussing key sub-topics using VOSviewer. • Over 200 articles from 70 countries, including PLOS ONE, have been published over the past 24 years, focusing on hyperuricemia, gout, management, prevalence, allopurinol risk, etc. • Our study outlines research hotspots, global cooperation models, and emerging hyperuricemia frontiers, emphasizing the need for standardized management processes and improved communication between research teams.
    Keywords:  Bibliometric; Health education; Health management; Hyperuricemia; VOSviewer
    DOI:  https://doi.org/10.1007/s10067-024-07247-1
  25. Medicine (Baltimore). 2024 Nov 29. 103(48): e40558
      To comprehensively review cardiorenal syndrome (CRS)-related research, this study analyzes its whole landscape and future trends from a bibliometric perspective. Using "cardiorenal syndrome" as the key word, a representative dataset of CRS was constructed in the Web of Science Core Collection (Science Citation Index Expanded) database up to November 2023. VOSviewer (version 1.6.18) and R-Studio (version 1.4) were used to visualize CRS-related author and national collaboration networks, hotspot distribution clustering and historical citation networks. The annual number of publications shows an upward trend, especially since 2009. The United States is the most active country and closely cooperates with European countries. Cardiorenal Medicine is the journal that publishes the most CRS-related research. Urology & Nephrology and Cardiovascular System & Cardiology are the most prominent areas of CRS literature output. The leaders in CRS-related research are Ronco C from Italy and Mccullough PA, from the United States. Combined with keyword co-occurrence, theme evolution, and strategic distribution analysis, it was found that centering on the mechanism of CRS (cardiovascular lesions, venous congestion, and fibrosis), prognosis (transplantation, dialysis, hospitalization, mortality) and cardiac function management (b-type natriuretic peptide, diastolic dysfunction, left ventricular hypertrophy) is a possible research direction for a long time to come. Although CRS has a relatively short history, it has received a lot of attention and is currently enjoying a high level of overall acceptance. In conclusion, this study explores the major research areas, frontiers and trends in CRS, which are important for future research.
    DOI:  https://doi.org/10.1097/MD.0000000000040558
  26. J Craniomaxillofac Surg. 2024 Nov 25. pii: S1010-5182(24)00315-9. [Epub ahead of print]
      Bibliometric analysis serves as a potent tool for deciphering the intricacies of scholarly communication and academic impact, contributing to an observable surge in publications of this nature. The objective of this study is to conduct a bibliometric analysis of self-citation in Maxillofacial Surgery (MFS) literature. The retrospective study adheres to the principles outlined in the Leiden Manifesto, utilizing Web of Science and Scopus databases for a robust analysis. Various bibliometric indicators, including H-index, MFS-related articles, and citing articles, are considered, with a focus on the impact of self-citation. The extensive bibliographic search retrieved 70,288 articles, allowing for the identification of 200 prolific authors from 25 countries in MFS literature. Despite potential limitations in sample size and retrospective nature, the study provides valuable insights. Notably, the self-citation rate stood at 46.94%, prompting a nicety examination of its impact on bibliometric indicators. Changes in H-index, exclusive MFS articles, and total publications exhibited low correlations with self-citation frequency, highlighting the complexity of this phenomenon. The study emphasizes the nuanced impact of self-citation on bibliometric indicators, cautioning against demonization and advocating for a balanced and individual perspective. The findings highlight the intricate link between self-citation, high productivity, expertise, and the specific dynamics of emerging research fields within MFS.
    Keywords:  Bibliometrics; Citations; Maxillofacial Injuries; Molar; Orthognathic surgery; Third
    DOI:  https://doi.org/10.1016/j.jcms.2024.11.013
  27. Front Med (Lausanne). 2024 ;11 1472413
       Objective: Sarcopenia is a significant healthcare challenge in the aging population. Oxidative stress (OS) is acknowledged to play a pivotal role in the pathological progression of sarcopenia. Numerous studies have demonstrated that mitigating or eliminating OS can ameliorate the pathological manifestations associated with sarcopenia. However, current clinical antioxidant therapies often fall short of anticipated outcomes. This bibliometric analysis aims to delineate prevailing research trends, thematic emphases, focal points, and developmental trajectories within the domain of OS in sarcopenia, while also endeavoring to explore prospective anti-oxidative stress strategies for future clinical interventions.
    Methods: Relevant publications were retrieved from the Web of Science (WOS) Core Collection database for the period 2000-2024. Citespace was employed for retrieving and analyzing trends and emerging topics.
    Results: In the field of OS in sarcopenia, the number of publications has significantly increased from 2000 to 2024. The United States and China are the primary contributors to global publication output. The most productive research institution is INRAE. The most prolific author is Holly Van Remmen from the United States, while the most frequently cited author is Cruz-Jentoft AJ from Spain. Experimental Gerontology is the journal with the highest volume of published articles, whereas the Journal of Gerontology Series A: Biological Sciences and Medical Sciences holds the record for the highest number of citations. The research keywords in this field can be categorized into eight domains: "Physiology and anatomy", "Physiological mechanisms", "Pathology associations", "Experimental studies", "Nutrition and metabolism", "Sports and physical activities", "Age" and "Oxidation and antioxidation". Moreover, recent years have seen the emergence of "TNF-α," "insulin resistance", "mitochondrial autophagy", "signal pathways", and "mechanisms" as focal points in the realm of OS in sarcopenia, encompassing related fundamental research and clinical translation.
    Conclusion: This bibliometric and visualization provides a comprehensive analysis of the global research landscape in the field of OS in sarcopenia, identifies priorities, summarizes the current research status and suggests possible future research priorities. In addition, in order to benefit more sarcopenia patients, strengthening cooperation and communication between institutions and research teams is the key to the future development of this field. Given the expectation that research on OS in sarcopenia will remain a prominent area of interest in the future, this article could serve as a valuable resource for scholars seeking to shape future studies through an understanding of influential scholarly contributions and key research findings.
    Systematic review registration: https://www.crd.york.ac.uk, identifier CRD42024528628.
    Keywords:  CiteSpace; bibliometric; bibliometric analysis; oxidative stress; sarcopenia
    DOI:  https://doi.org/10.3389/fmed.2024.1472413
  28. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2429893
      Immune checkpoint inhibitors (ICIs) are revolutionizing cancer treatment, and Artificial Intelligence (AI) is a key player in this field. A comprehensive analysis of AI's impact on these inhibitors was lacking, but this study addresses that by analyzing literature for trends and future predictions. It reveals rapid growth and international collaboration. We utilized analytical tools such as CiteSpace, VOSviewer, and PlotDB to analyze 774 documents from the Web of Science Core Collection from 2018 to May 2024, discovering a steady increase in annual publications, with China and the United States leading the way. Sun Yat Sen University and researchers like Ock Chan-young, Zhang Hao, and Newman AM are prominent. The most productive journal is Frontiers in Immunology, while the New England Journal of Medicine has the highest citation rate. The most cited reference is Newman, AM's 2019 article in Nature Biotechnology. Keywords like "immunotherapy," "pembrolizumab," "cancer," "machine learning," and "expression" are central to the discourse. Research focuses on the application of inhibitors in non-small cell lung cancer, bioinformatics, and cancer immunotherapy, showing AI's potential to improve oncology precision medicine. Although AI's application in ICIs shows promise, significant challenges still demand exploration and resolution. Continued investment in AI research in this context could lead to significant advancements in cancer treatment. Global collaboration is needed to overcome these challenges and fully leverage AI's potential. This study provides a foundation for future research and interdisciplinary collaboration in this critical field.
    Keywords:  CiteSpace; Immune checkpoint inhibitors; VOSviewer; artificial intelligence; bibliometrics; immunotherapy
    DOI:  https://doi.org/10.1080/21645515.2024.2429893
  29. Medicine (Baltimore). 2024 Nov 29. 103(48): e40552
      Repeated and prolonged exposure to pain can impair neurodevelopmental, behavioral, and cognitive outcomes in newborns. Effective pain management of newborns is essential, but there is no comprehensive analysis of the status of neonatal pain non-pharmacologic management research. Original publications related to the non-pharmacological management of neonatal pain were obtained from the Web of Science Core Collection (WOSCC) between 1989 and 2024. CiteSpace and VOSviewer were used to extract information about countries/regions, institutions, authors, keywords, and references to identify and analyze the research hotspots and trends in this field. 1331 authors from 51 countries and 548 institutions published studies on the non-pharmacological management of neonatal pain between 1989 and 2024, with the number of publications showing an overall upward trend. Canada emerged as the leading country in terms of publication volume, with the University of Toronto and The Hospital for Sick Children identified as key research institutions. High-frequency keywords included "procedural pain," "management," "sucrose," "analgesia," and "preterm infant," resulting in 11 clusters. Keyword emergence analysis revealed that "neonatal pain," "analgesia," "oral sucrose," and "oral glucose" were research hotpots. Analysis of highly cited papers showed that the most referenced articles were published in the Clinical Journal of Pain. Researchers' interest in neonatal procedural pain has increased significantly over the past 30 years. This article can serve as a theoretical reference for future research on mild to moderate pain in neonates and infants, and it can provide ideas for exploring novel and secure pain management strategies.
    DOI:  https://doi.org/10.1097/MD.0000000000040552
  30. J Pediatr Urol. 2024 Nov 18. pii: S1477-5131(24)00606-5. [Epub ahead of print]
       BACKGROUND: Historically, word of mouth, total citation count, H-index, and expert opinion were some of the primary metrics used to identify the most influential papers. This method is subject to significant bias. The disruption score was initially created with the intent of measuring the degree to which a publication introduces a new idea, is repeatedly referenced and may be used as an additional publication evaluation metric.
    OBJECTIVE: To use disruptive score, a novel bibliometric index to identify influential papers in pediatric urology.
    METHODS: A customized search was executed using PubMed to identify papers from NEJM, JAMA, European Urology, Journal of Urology, Urology, Journal of Pediatric Urology, and Journal of Pediatric Surgery between 1954 to 2022 to identify pediatric urology related publications. Once accrued, all papers collected were run through a validated data set to identify a disruption score, where the 50 most disruptive papers were identified. The disruption score ranged from 1 to -1, with a positive score representing papers that are disruptive (challenge current knowledge), whereas a negative score represents developmental papers (help support previous publications). The 50 most disruptive papers were then cross referenced with the NIH iCite tool to identify how many times the article was cited and then the most disruptive articles and the most cited articles were compared.
    RESULTS: In total, 12,085 articles were identified and included. The database for analysis of disruption score included articles published from 1954 to 2014, leaving a total of 6544 of the papers for which a disruption score was calculated. Most of the articles identified were published in the Journal of Urology (n = 32) and Journal of Pediatric Surgery (n = 15). Fourteen of the top 50 papers were published prior to 1980 and 7 after 2000. Of the 35 total articles with iCite data available, only 8 articles had greater than 100 total citations.
    DISCUSSION: Many of the most disruptive articles identified did not have a large number of citations, highlighting the need to look beyond citation counts when assessing article importance. While this method was able to highlight some lesser-known articles, it does not appear that these citations are all highly impactful, which may be due to the relative youth of the field.
    CONCLUSION: Disruption score provides a new way to assess the impact of publications within the field of pediatric urology. While novel, we feel this metric should be used with caution in pediatric urology at this time.
    Keywords:  Bibliometric; Pediatric; Urology
    DOI:  https://doi.org/10.1016/j.jpurol.2024.11.011
  31. Front Microbiol. 2024 ;15 1479703
       Introduction: In recent years, an increasing body of research has illustrated a strong correlation between gut microbiota and depression. However, there has yet to be a comprehensive discussion or summary of the latest advancements and trends in this field.
    Methods: We retrieved research articles focused on gut microbiota and depression through the WOS database from 2020 to 2024, using visual text analysis tools such as CiteSpace and VOSviewer.
    Results: The literature on the relationship between gut microbiota and depression surged from 396 papers in 2020 to 711 by 2024. During this period, the journal with the highest publication rate was Nutrients. China led the countries in contributions, while University College Cork topped the institutions. Kenji Hashimoto emerged as the most prolific author. The most cited paper was authored by Cryan JF et al., published in 2019 in Physiol Rev. The keywords "gut microbiota," "depression," and "anxiety" appeared most frequently, while recent years saw explosive increases in terms such as "growth performance," "receptors," "depression-like phenotypes," "stress response," "gastrointestinal symptoms," "reliability," and "neurogenesis."
    Discussion: Our article displayed the overview of the relationship between the gut microbiome and depression from 2020 to 2024 using bibliometric methods, providing perspectives and research hotspots for studies exploring the correlation between the gut microbiome and depression.
    Keywords:  authors; bibliometric analysis; depression; gut microbiota; publication
    DOI:  https://doi.org/10.3389/fmicb.2024.1479703
  32. Medicine (Baltimore). 2024 Nov 29. 103(48): e40729
       BACKGROUND: Diabetic nephropathy (DN) is a common complication of diabetes, which is prone to develop into end-stage renal disease, and early diagnosis and treatment is the key to effective management of DN. Biomarkers have important clinical significance in the diagnosis and treatment of DN and have attracted extensive attention from researchers in recent years. The aim of this study was to visualize the field of biomarker research in DN through bibliometric analysis, to summarize the current status and predict future trends of this field, with a view to providing valuable insights for scholars and policy makers.
    METHODS: Literature search and data collection from Web of Science Core Collection. Calculations and visualizations were performed using Microsoft Excel, VOSviewer, Bibliometrix R-package, and CiteSpace.
    RESULTS: We identified 1274 publications about biomarker research in DN from 1995 to November 01, 2023, with a steady increase in annual publications. China, Steno Diabetes Center in Denmark, and Frontiers in Endocrinology were the most productive country, institution, and journal, respectively; Mischak, Harald was both the most productive and highly cited author, and Kidney International was the most cited journal. The high frequency keywords were "albuminuria," "chronic kidney disease" and "expression." In addition, "macrophage," "fibrosis" and "omics" are potentially promising topics.
    CONCLUSION: Our study comprehensively and visually summarized the important findings of global biomarker research in DN and revealed the structure, hotspots, and evolutionary trends in this field. It would inspire subsequent studies from a macroscopic perspective and provide a basis for rational allocation of resources and identification of collaborations among researchers.
    DOI:  https://doi.org/10.1097/MD.0000000000040729
  33. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2429237
      Immunotherapy has emerged as a crucial advancement in pulmonary carcinoma treatment. Nevertheless, its unique side effects not only reduce patients' quality of life but also affect treatment efficacy, with severe cases potentially endangering the patient's life. This study uses bibliometric analysis to perform a comprehensive bibliometric analysis literature on IRAEs in lung cancer from 1991 to 2023, retrieved from the Web of Science database. The dataset was analyzed using VOSviewer and CiteSpace to identify trends, key contributors, and emerging research areas. A total of 124 publications were analyzed, revealing a notable increase in research activity post-2015, with China and the USA contributing over 50% of the studies. This research highlights the importance of understanding IRAEs and suggests future investigations into the pulmonary microbiota and tumor microenvironment.
    Keywords:  Bibliometrics; Pulmonary carcinoma; adverse events; immune; visualization analysis
    DOI:  https://doi.org/10.1080/21645515.2024.2429237
  34. Front Immunol. 2024 ;15 1442694
       Background: Multiple sclerosis (MS) is a chronic, progressive autoimmune disease, with increasing attention on the role of B cells in its pathogenesis. Despite this growing interest, a comprehensive analysis of research trends and emerging foci on B cells in MS is currently lacking. In this research, we utilize a bibliometric approach to visualize and analyze research trends and focal points in this field, offering a valuable reference for future mechanistic studies in MS.
    Methods: We retrieved bibliometric data from the Web of Science Core Collection (WOSCC) for articles published between 2014 and 2023. VOSviewer 1.6.18 and CiteSpace 5.7R3 were used for co-authorship, co-occurrence, and citation analyses to identify key researchers, institutions, countries, and emerging themes in B cell research related to MS.
    Results: The analysis examined 5,578 articles published in 1,041 journals by 5,337 institutions globally. The United States leads in publication output, with Amit Bar-Or identified as the most influential author, and Frontiers in Immunology as the top journal in the field. Research has increasingly focused on the complex role of B cells in MS, particularly their involvement in the central nervous system (CNS) and mechanisms of anti-B cell therapy. Recent trends point to a growing focus on meningeal inflammation, kinase inhibitors, and Epstein-Barr virus, signaling a shift in research priorities.
    Conclusion: This bibliometric analysis highlights pivotal research trends, key contributors, and emerging areas of interest in B cell research in MS from 2013 to 2024. The findings underscore the growing recognition of the multifaceted role of B cells in MS pathogenesis, particularly their involvement in the CNS compartment and the potential of targeted therapies. The study identifies meningeal inflammation, Epstein-Barr virus infection, and kinase inhibitors as promising avenues for future research. The analyses driving the in-depth exploration of B cell mechanisms in MS and the development of novel diagnostic and therapeutic strategies provide researchers in the MS field with a comprehensive and objective perspective, serving as a valuable reference for accelerating the translation of basic research findings into clinical applications.
    Keywords:  B cells; CiteSpace; VOSviewer; multiple sclerosis; neurodegeneration
    DOI:  https://doi.org/10.3389/fimmu.2024.1442694
  35. J Sport Rehabil. 2024 Nov 26. 1-9
       CONTEXT: The rehabilitation of disabled athletes is a critical area of research aimed at improving athletes' performance and well-being. This bibliometric analysis examines scientific studies related to the rehabilitation of disabled athletes, focusing on trends, authors, publications and interdisciplinary collaborations.
    OBJECTIVE: This study seeks to provide quantitative and qualitative insights into the trends, interdisciplinary collaborations, and significant contributions in the rehabilitation of disabled athletes.
    DESIGN: Bibliometric analysis of 660 scientific publications related to the rehabilitation of disabled athletes, from 1975 to 2023.
    SETTING: The analysis reveals that research in this field is multidisciplinary, encompassing sports, medicine, rehabilitation and education. Studies focused on disabled athletes and their rehabilitation.
    INTERVENTION: Rehabilitation plays a vital role in disabled athletes' lives, aiding in injury recovery and enhancing overall health and performance.
    RESULTS: The United States leads in research output. Collaborative networks among authors are evident, indicating joint research efforts. Identification of research trends, prominent authors  Bartosz Molik and Natalia Morgulec-Adamowicz), collaborative networks and common keywords (e.g., adaptive sports, disability, rehabilitation). Keywords such as adaptive sports, disability and rehabilitation are frequently mentioned, reflecting the focus of research.
    CONCLUSIONS: The rehabilitation of disabled athletes is a growing field with significant contributions from researchers worldwide. Collaborative efforts and interdisciplinary approaches are essential for advancing knowledge and improving the lives of disabled athletes.
    Keywords:  adaptive sports; collaboration; interdisciplinary
    DOI:  https://doi.org/10.1123/jsr.2024-0112
  36. Front Oncol. 2024 ;14 1428307
      In recent years, the integration of immunotherapy in the treatment of lung cancer has marked a significant evolution in the field. This is evidenced by the surge in the volume of scientific publications, reflecting rapid advances over time. This paper presents a bibliometric analysis of lung cancer and immunotherapy research from January 2012 to December 2022, drawing on the Web of Science literature database and using the citexs data analysis platform to examine the shifts in topic hotspots over the decade. A total of 8,722 publications were retrieved, with annual publication numbers soaring from 79 in 2012 to 2,112 in 2021. The most prolific country in terms of publication volume was China (n = 3,363, 38.56%), with The University of Texas MD Anderson Cancer Center making the most significant institutional contribution (n = 156, 1.79%). Notably, the most productive authors in this domain were Benjamin Besse and Marina Chiara Garassino, who have collectively published 35 articles to date. Predominant research themes include PD1/PDL1, clinical trials, pembrolizumab, nivolumab, and immune checkpoint inhibitors. Moreover, this paper visualizes the analysis of journals, keywords, key genes and targets, and associated diseases, aiming to provide a systematic review and a forward-looking perspective on research in lung cancer and immunotherapy. By exploring current research dynamics and hotspots and identifying areas for improvement, this study seeks to provide valuable insights for future investigations in this burgeoning field.
    Keywords:  CiteSpace; bibliometric analysis; immunotherapy; lung cancer; visual analysis
    DOI:  https://doi.org/10.3389/fonc.2024.1428307
  37. Front Nutr. 2024 ;11 1480856
       Objective: The Mediterranean diet (MedDiet) has been found to have benefits for diabetes mellitus (DM), but a bibliometric analysis of its association with DM has yet to be conducted. This paper aims to explore the current status and research hotspots on the connection between the Mediterranean diet and DM from 2014 to 2024, providing a reference for future studies.
    Methods: We retrieved articles published between 2014 and 2024 from the Web of Science database and analyzed them using R software, VOSviewer, and CiteSpace.
    Results: A total of 2,806 articles were included in this study. Research on the relationship between the MedDiet and DM showed a steady increase in publication volume from 2014 to 2019, followed by a sharp rise from 2020 to 2023. Spain was the leading country in terms of publication volume, followed by Italy, the United States, China, and Greece. Spain also led in international collaborations, with CIBER-Centro de Investigación Biomédica en Red and Harvard University being the most prominent collaboration centers. Nutrients was the most frequently published and cited journal in this field. Common keywords in this literature included components such as olive oil, legumes, and red wine. Mechanisms studied in this field primarily focused on antioxidant effects, improvements in insulin sensitivity and secretion, regulation of lipid metabolism, and modulation of gut microbiota.
    Conclusion: Research on the beneficial effects of the MedDiet on DM patients has garnered significant attention from researchers worldwide, and it is expected to become a major focus for future DM prevention and treatment. This study provides a comprehensive analysis of the current status and research hotspots regarding the relationship between the MedDiet and DM, offering valuable references for future research.
    Keywords:  antioxidant; bibliometric analysis; chronic disease prevention; gut microbiota; insulin sensitivity
    DOI:  https://doi.org/10.3389/fnut.2024.1480856
  38. Clin Spine Surg. 2024 Dec 01. 37(10): E512-E521
       STUDY DESIGN: Bibliometric analysis.
    OBJECTIVE: This study explored the current research status, hotspots, and trends in the application of endoscopic techniques for treating lumbar disc herniation (LDH).
    BACKGROUND: Endoscopic techniques are widely used to treat LDH, but there are no bibliometric studies on endoscopic technology and LDH.
    METHODS: The Web of Science Core Collection database was used as the data source. Based on the principles of bibliometrics, we apply VOSviewer and CiteSpace software to conduct the data statistics and visual analysis.
    RESULTS: A total of 965 studies were included, with 11893 citations (12.32 per study). The top 3 countries with the largest number of papers published are China (529), South Korea (164), and the United States (108). Yong Ahn and Jin-Sung Kim are prolific authors in this field. Representative academic journals are World Neuroscience, Pain Physician, and BioMed Research International. The results of keyword cooccurrence analysis indicate that the research topics in this field in the past decade have mainly focused on microdiscectomy, complications, percutaneous endoscopic lumbar discectomy, decompression, and the learning curve. Keyword burst analysis suggested that endoscopic drug injection and the identification of risk factors for LDH are the frontiers and trends for future research.
    CONCLUSION: The application of endoscopic techniques for LDH has received widespread attention from researchers, and research in this field has focused on percutaneous endoscopic lumbar discectomy, endoscopic decompression, complications, and the learning curve of endoscopic techniques. Future research trends will focus on the efficacy of endoscopic drug injection therapy for LDH and the identification of risk factors for LDH treatment failure.
    DOI:  https://doi.org/10.1097/BSD.0000000000001648
  39. J Multidiscip Healthc. 2024 ;17 5375-5406
      This study offers new insights into college students' health education (CSHE) regarding its research status, hot spots, and trends by conducting a comprehensive bibliometric analysis of this field in the past decade (2014 to 2024). Specifically, we analyzed publication trends and used the bibliometric method with CiteSpace software to explore collaborative networks, detailed co-citation status, and co-occurrence dynamics based on 1358 Web of Science Core Collection articles. Our results indicate increased relevant publications and the collaboration networks show complex institutional and regional partnerships. At the same time, co-citation and co-occurrence analyses highlight interdisciplinary research themes that encompass public health. The study particularly underscores the emerging importance of mental health, global health, and innovative educational approaches. These findings reveal trends in CSHE research and provide crucial insights for future studies, stressing the need for interdisciplinary collaboration and creative strategies to tackle student health challenges. Moreover, in practice, this study contributes to promoting and practicing targeted health intervention policies and countermeasures aimed at enhancing student well-being, such as establishing dedicated health education courses, providing specialized training for teachers, conducting regular health assessments, and providing funding for CSHE.
    Keywords:  CiteSpace; college student; global health; health education; systematic review
    DOI:  https://doi.org/10.2147/JMDH.S479983
  40. Front Oncol. 2024 ;14 1399486
       Objective: Dermatofibrosarcoma protuberans (DFSP) is a moderately malignant soft tissue sarcoma with localized infiltrative growth. The extensive surgical scope and high recurrence rate of DFSP brings dysfunctional, aesthetic, psychological and economic problems to patients. The aim of this study is to explore the global publication characteristics, research hotspots and future trends of DFSP over the past 32 years via an intuitive visualized way.
    Methods: The Web of Science Core Collection (WoSCC) database was searched for papers related to DFSP published from 1990 to 2022. Then bibliometric analysis of these publications was performed, including collaborative networks, co-citation analysis of journals and references, and cluster analysis of keywords.
    Results: A total of 1588 papers were retrieved between 1990-2022. The United States was the most prolific country, followed by China. The article Imatinib Mesylate in Advanced Dermatofibrosarcoma Protuberans: Pooled Analysis of Two Phase II Clinical Trials, received most citations. Research hotspots and future trends are mainly focused on disease diagnosis, COL1A1-PDGFB fusion gene, drug and surgical treatment, fibrosarcomatous transformation, and immunotherapy.
    Conclusion: The research on DFSP faces several clinical challenges. This study provides novel insights into future research directions and scientific decisions for DFSP.
    Keywords:  bibliometric analysis; dermatofibrosarcoma protuberans; fibrosarcomatous transformation; fusion gene; immunotherapy; tumor microenvironment
    DOI:  https://doi.org/10.3389/fonc.2024.1399486
  41. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2024 Nov 20. 42(11): 831-837
      Objective: To use CiteSpace and VOSviewer software to perform visualization analysis on research literature on sudden poisoning incidents in China from 2013 to 2022, in order to grasp the research hotspots and priorities, current research development status and trend of sudden poisoning incidents, and provide reference and ideas for subsequent research. Methods: In October 2023, literature related to sudden poisoning incidents was searched using the China National Knowledge Infrastructure and Wanfang databases. The bibliometric analysis software CiteSpace 6.1.R2 and VOSviewer 1.6.19 were used to visually analyze factors such as authors, institutions, journals, regions, and keywords in the relevant literature. Results: A total of 2578 valid literatures were included, and the overall number of published literatures showed a discontinuous downward trend in recent 10 years. The relevant literature was distributed in 310 journals. Among the top 10 institutions with the highest number of publications, 8 were centers for disease control and prevention at all levels, and the institution with the highest number of publications was the Chinese Center for Disease Control and Prevention (208 articles), but the cooperation between institutions was not obvious. The 2578 articles involved a total of 6549 authors (a total of 8572 appearances, with an average of 1.31 times per person), with a collaboration rate of 2.54 (6549/2578) and 2153 co-authored articles (with 2 or more authors in the literature), with a co-authorship rate of 83.51%. 643 articles (24.94%) received funding support. The region with the highest number of publications was Guangdong Province, with a total of 380 articles (14.74%). Keyword highlighting analysis showed that the research heat of pesticide poisoning, toxic mushrooms, disease characteristics, outbreak events, traceability analysis, outbreaks, and occupational diseases continued to 2022. Conclusion: There are many literatures on sudden poisoning incidents in China, so it is necessary to strengthen the cooperation and communication between institutions and authors. In practical work, the ability of prevention, control, and detection of poisons should be continuously improved to reduce the incidence and degree of harm caused by sudden poisoning incidents.
    Keywords:  Bibliometrics; CiteSpace; Poisoning; Sudden poisoning incidents; VOSviewer; Visualization analysis
    DOI:  https://doi.org/10.3760/cma.j.cn121094-20231130-00140
  42. Int J Gen Med. 2024 ;17 5397-5414
       Background: Integrating Traditional Chinese Medicine (TCM) knowledge with modern technology, especially machine learning (ML), has shown immense potential in enhancing TCM diagnostics and treatment. This study aims to systematically review and analyze the trends and developments in ML applications in TCM through a bibliometric analysis.
    Methods: Data for this study were sourced from the Web of Science Core Collection. Data were analyzed and visualized using Microsoft Office Excel, Bibliometrix, and VOSviewer.
    Results: 474 documents were identified. The analysis revealed a significant increase in research output from 2000 to 2023, with China leading in both the number of publications and research impact. Key research institutions include the Shanghai University of Traditional Chinese Medicine and the China Academy of Chinese Medical Sciences. Major research hotspots identified include ML applications in TCM diagnosis, network pharmacology, and tongue diagnosis. Additionally, chemometrics with ML are highlighted for their roles in quality control and authentication of TCM products.
    Conclusion: This study provides a comprehensive overview of ML applications' development trends and research landscape in TCM. The integration of ML has led to significant advancements in TCM diagnostics, personalized medicine, and quality control, paving the way for the modernization and internationalization of TCM practices. Future research should focus on improving model interpretability, fostering international collaborations, and standardized reporting protocols.
    Keywords:  artificial intelligence; bibliometric; machine learning; review; traditional Chinese medicine
    DOI:  https://doi.org/10.2147/IJGM.S495663
  43. J Pediatr Nurs. 2024 Nov 28. pii: S0882-5963(24)00432-9. [Epub ahead of print]80 100-107
       PROBLEM: The present study explores research on family resilience in the context of children and adolescents, as well as studies covering all family members, and examines the conceptual, intellectual, and social structures of the research through bibliometric analysis.
    MATERIALS AND METHODS: We carried out the search procedure on the abstracts of papers indexed to Social Science Citation Index (SSCI), Science Citation Index Expanded (SCI-E), Emerging Sources Citation Index (ESCI), and Arts & Humanities Citation Index (AHCI) within the Web of Science (WoS) database.
    RESULTS: We could access 407 papers since 1994 pertaining to the topic of family resilience in the context of children and adolescents. These records are distributed across 245 sources, and we calculated the annual growth rate of the research to be 14.49. The United States of America seems to lead the research field, followed by China and Canada. Moreover, we present findings regarding the conceptual, intellectual, and social structures of the selected research.
    CONCLUSION: We conclude that family resilience is an important issue in the context of children and adolescents. In this sense, our findings would provide a foundation for further investigation into family resilience in the mentioned context. Finally, we anticipate that our results will contribute to evidence-based policies concerning family resilience in the context of children and adolescents.
    PRACTICAL IMPLICATIONS: The study offers a comprehensive view of family resilience in the context of children and adolescents, particularly in the domain of health. Furthermore, it provides insights into bibliometric analysis.
    Keywords:  Bibliometric analysis; Family resilience; Resilience in family
    DOI:  https://doi.org/10.1016/j.pedn.2024.11.014
  44. Vector Borne Zoonotic Dis. 2024 Nov 25.
      Background: The global burden of mosquito-borne diseases transmitted by Aedes aegypti and Aedes albopictus mosquitoes has become a pressing public health concern. This study sought to quantify and evaluate about eight decades of publication data on the global epidemiological trend of the diseases transmitted by A. aegypti and A. albopictus. Methods: A comprehensive bibliographic review of literature was performed on A. aegypti and A. albopictus transmitted diseases, focusing on disease transmission, epidemiological trends, vector control strategies, surveillance and monitoring, and international collaborations and initiatives. Extensive data were collected from the Web of Science database and analyzed for citation network analysis (CNA) using VoSviewer software. Data were collected from the Web of Science database encompassing various aspects of Aedes-borne diseases. The bibliographic CNA was performed to quantify and analyze the 77 years of data on A. aegypti and A. albopictus transmitted diseases. Results: The analysis included 4149 publications contributed by 13,416 authors from 149 countries. These articles comprised research articles (91.01%), review articles (6.267%), proceeding papers (1.76%), and book chapters (0.92%). The results revealed a cumulative h-index of 134, indicating the impact of the scientific output in this field. Conclusion: This review contributes to the ongoing efforts to mitigate the impact of Aedes-borne diseases and protect public health worldwide. By synthesizing current knowledge and evidence-based practices, the study provides all information related to publications, citations, co-citations, top journal trends, high-impact publications, and collaborations among authors in one place among the data published in the past eight decades on Aedes-borne diseases.
    Keywords:  Aedes aegypti; Aedes albopictus; Zika; chikungunya; citation network analysis; dengue; yellow fever
    DOI:  https://doi.org/10.1089/vbz.2024.0081
  45. Front Med (Lausanne). 2024 ;11 1501652
       Background: Radiomics, which involves the conversion of digital images into high-dimensional data, has been used in oncological studies since 2012. We analyzed the publications that had been conducted on this subject using bibliometric and visual methods to expound the hotpots and future trends regarding radiomics in evaluating lymph node status in oncology.
    Methods: Documents published between 2012 and 2023, updated to August 1, 2024, were searched using the Scopus database. VOSviewer, R Package, and Microsoft Excel were used for visualization.
    Results: A total of 898 original articles and reviews written in English and be related to radiomics for evaluating lymph node status in oncology, published between 2015 and 2023, were retrieved. A significant increase in the number of publications was observed, with an annual growth rate of 100.77%. The publications predominantly originated from three countries, with China leading in the number of publications and citations. Fudan University was the most contributing affiliation, followed by Sun Yat-sen University and Southern Medical University, all of which were from China. Tian J. from the Chinese Academy of Sciences contributed the most within 5885 authors. In addition, Frontiers in Oncology had the most publications and transcended other journals in recent 4 years. Moreover, the keywords co-occurrence suggested that the interplay of "radiomics" and "lymph node metastasis," as well as "major clinical study" were the predominant topics, furthermore, the focused topics shifted from revealing the diagnosis of cancers to exploring the deep learning-based prediction of lymph node metastasis, suggesting the combination of artificial intelligence research would develop in the future.
    Conclusion: The present bibliometric and visual analysis described an approximately continuous trend of increasing publications related to radiomics in evaluating lymph node status in oncology and revealed that it could serve as an efficient tool for personalized diagnosis and treatment guidance in clinical patients, and combined artificial intelligence should be further considered in the future.
    Keywords:  artificial intelligence; bibliometric analysis; lymph node; oncology; radiomics
    DOI:  https://doi.org/10.3389/fmed.2024.1501652
  46. Int J Environ Res Public Health. 2024 Oct 24. pii: 1405. [Epub ahead of print]21(11):
      Gestational diabetes mellitus (GDM) represents a significant medical complication during pregnancy, with a global prevalence ranging from 2% to 26% and increasing by over 30% in recent decades. Therefore, the aim of our study is to assess the trends and distribution of published studies, as well as the contributions of countries, institutions, journals, and authors to the development of primary care for pregnant women with gestational diabetes. In this bibliometric analysis, we examine the role of primary health care in GDM from 1991 to 2024. The data were sourced from Scopus and Web of Science, encompassing 276 articles from 150 sources and involving 1375 authors. The analysis reveals a steady increase in publications, with a 4.29% annual growth rate. This study identifies the USA and UK as leading countries in GDM research, and there are significant international collaborations, with the USA having 17 joint articles with other countries. The University of Eastern Finland, Ohio State University, and Harvard University are noted as the most prolific institutions, with 23, 17, and 16 articles, respectively. Additionally, the journal Diabetes Care published the highest number of articles, totaling 635. Prominent authors such as Bernstein J. and McCloskey L., with seven articles each, have made substantial contributions to the field. Our work highlights the need to pay special attention to primary care for gestational diabetes, as many negative consequences of the disease can be prevented at this stage. Innovative approaches to screening for GDM can significantly improve treatment outcomes and reduce health risks, which will have long-term positive effects both for individual patients and society as a whole.
    Keywords:  bibliometric analysis; gestational diabetes; primary health care
    DOI:  https://doi.org/10.3390/ijerph21111405
  47. Med Oral Patol Oral Cir Bucal. 2024 Nov 25. pii: 26582. [Epub ahead of print]
       BACKGROUND: Chronic obstructive pulmonary disease (COPD) and periodontitis are common chronic diseases. The presence of either of the two diseases increases the risk of the other, whereas managing one reduces the risk of the other. This study aimed to summarize the current state of research and trends in this field using bibliometric analysis and visualization.
    MATERIAL AND METHODS: We used PubMed to search and download all periodontal disease- and COPD-related studies published until August 20, 2023. We further performed bibliometric analysis on the text R and Python software and visualized the results using Gephi and VOSviewer to construct latent Dirichlet allocation models that summarize idiosyncratic research themes.
    RESULTS: A total of 2, 109 publications were analyzed, with recent ones focusing on risk factors and pandemics. The country that produced the most publications was the United States with 427 publications. The most cited article was by Prof. Wang Zuomin. International Journal of Chronic Obstructive Pulmonary Disease ranked first in publications. Keywords were focused on Risk Factors and Pandemics. In addition, COVID- 19, SARS-CoV-2 and coronavirus infections have become a research hotspot since 2020. However, little attention has been paid to environmental contamination and biological mechanisms.
    CONCLUSIONS: Research on periodontitis and COPD is expanding, and it currently focused on exploring risk factors and conducting clinical epidemiological studies. This exhaustive study provides a comprehensive summary of trends in this field and has important clinical implications for the screening and treatment of patients with COPD and periodontitis.
    DOI:  https://doi.org/10.4317/medoral.26582
  48. J Multidiscip Healthc. 2024 ;17 5445-5455
       Introduction: Cardiovascular diseases (CVDs) stand as the foremost global cause of mortality, accounting for 32% of total deaths in 2019, with 85% attributed to heart attacks and strokes. Individuals with Type 2 Diabetes Mellitus (T2DM) exhibit an elevated susceptibility to coronary heart disease (CHD). In numerous studies, it has been established that genetic polymorphism of genes influences the onset, progression, and complications of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM). The aims of this study are to employ bibliometric analysis methods for mapping the array of research on genome variability concerning the development of coronary heart disease in individuals with type 2 diabetes mellitus.
    Methods: We derived the data from the Web of Science (WoS) Core Collection database and Scopus on January 6, 2023. All publications from 1987 to 2023 are exported in plain text format for WoS-CC and BibTeX format for Scopus, containing bibliographic information, keywords, and citation information. RStudio v.4.1.2 software (RStudio, PBC, Boston, MA, USA) was used for conducting bibliometric analysis.
    Results: Our analysis of 241 articles published between 1987 and 2023 revealed a consistent increase in research output, especially after 2004, highlighting a growing academic focus on genome variability's role in coronary heart disease (CHD) development among Type 2 Diabetes Mellitus (T2DM) patients. Key contributing journals include The Lancet and Nature Genetics, indicating high-impact interest in this domain. The United States leads in research productivity and collaboration, with China also emerging as a notable contributor in recent years. Prominent authors such as S. Humphries have significantly shaped the field, contributing to a cumulative knowledge base that underscores the role of genetic factors in CHD among T2DM patients.
    Discussion: Our findings underscore the value of bibliometric studies in guiding future research directions. This increasing scholarly attention to genome variability in CHD and T2DM may encourage deeper investigation into specific genetic polymorphisms and their mechanistic roles in disease progression. Additionally, these insights can help prioritize collaboration across leading research hubs and potentially drive innovation in therapeutic interventions targeting genetic risk factors in CHD and T2DM. Future research could build on these trends by focusing on comparative studies across populations, advancing precision medicine approaches for at-risk individuals with T2DM.
    Keywords:  Bibliometric Analysis; Coronary Heart Disease; Genome Variability; Research Hotspots; Type 2 Diabetes Mellitus
    DOI:  https://doi.org/10.2147/JMDH.S471606
  49. Front Oncol. 2024 ;14 1450675
       Background: Late diagnosis and patient relapse, mainly due to chemoresistance, are the key reasons for the high mortality rate of ovarian cancer patients. Hence, the search for biomarkers of high predictive value within the phenomenon of chemoresistance is vital. This study performs a bibliometric analysis of the scientific literature concerning biomarkers of drug resistance in ovarian cancer, considering the period from 2017 to 2022.
    Methods: The terms "drug resistance biomarker" and "ovarian cancer" were linked by the Boolean operator "AND". The search was done in PubMed, selecting documents published over the last 5 years (2017-2022), which were analyzed with the open-source tool Bibliometrix developed in the R package. The language of the publications was restricted to English. Several types of papers such as case reports, clinical trials, comparative studies, and original articles were considered.
    Results: A total of 335 scientific articles were analyzed. The United States and China were the leading contributors and established the largest number of scientific collaborations. The Huazhong University of Science and Technology and the University of Texas MD Anderson Cancer Center were the most influential institutions. The Journal of Ovarian Research, International Journal of Molecular Science, and Scientific Reports are among the most relevant journals. The study identified high-profile, relevant thematic niches and important descriptors that indicate topics of interest, including studies on women, cell lines, solid tumors, and gene expression regulation. As well as studies involving middle-aged and adult participants, and those focusing on prognosis evaluation. Descriptors such as "drug resistance," "neoplasm," "genetics," "biomarker," "gene expression profile," and "drug therapy" would indicate new research trends. In addition, we propose that BCL-2, CHRF, SNAIL, miR-363, iASPP, ALDH1, Fzd7, and EZH2 are potential biomarkers of drug resistance.
    Conclusions: This paper contributes to the global analysis of the scientific investigation related to drug resistance biomarkers in ovarian cancer to facilitate further studies and collaborative networks, which may lead to future improvements in therapy for this lethal disease.
    Keywords:  bibliometric analysis; bibliometrix; biblioshiny; biomarkers; chemoresistance; descriptor; drug resistance; ovarian cancer
    DOI:  https://doi.org/10.3389/fonc.2024.1450675
  50. Can J Respir Ther. 2024 ;60 173-175
      
    Keywords:  Allied health personnel; Bibliometrics; Journal Impact Factor; Respiratory Therapy
    DOI:  https://doi.org/10.29390/001c.125457
  51. Cell Mol Biol (Noisy-le-grand). 2024 Nov 24. 70(10): 182-192
      Artificial intelligence (AI) and microbiome have emerged in recent years as transformative fields with far-reaching implications for various biomedical domains. This paper presents a comprehensive bibliometric analysis examining the intersection of AI and the microbiome (AIM). The study aims to provide information on this interdisciplinary field's research landscape, trends, and emerging topics. Using a systematic approach, data-driven studies were extracted from the Scopus database on 23 November 2023 and analyzed using the VOSviewer and Bibliometrix applications. The regression coefficient of 0.94 and the yearly growth rate of 7.46% in AIM production indicate a consistent increase over time. Identification of essential contributors, organizations, and nations illuminated cooperative networks and research hotspots. The trend themes are the gut microbiome, disease prediction, machine learning, transfer learning, categorization, big data, artificial neural networks, chronic rhinosinusitis, epidemiology, COPD, and bronchoalveolar lavage. These hot issues in AIM reflect the present emphasis on research and developments in our knowledge of the microbiome's function in health, sickness, and individualized treatment. The findings give researchers, policymakers, and industry experts a thorough picture of the research environment and guide future paths in AIM's fascinating and promising subject.
    DOI:  https://doi.org/10.14715/cmb/2024.70.10.24
  52. Curr Probl Diagn Radiol. 2025 Jan-Feb;54(1):pii: S0363-0188(24)00190-7. [Epub ahead of print]54(1): 75-80
       PURPOSE: This study aimed to evaluate the degree of gender disparity in leadership positions at the top 25 medical schools in North America compared to their affiliated radiology departments.
    METHODS: The academic rank and leadership appointment of medical school and radiology faculty were obtained from publicly available official websites between June-November 2022. Gender was determined using self-identified pronouns on website biographies. Alternatively, gender API software was used. Finally, SCOPUS Elsevier was used to extract research output metrics including publication counts, citations, and h-indices. Statistical analysis was conducted using the IBM SPSS Statistics version 25 software.
    RESULTS: 2216 individuals across 25 medical schools were included in this study. 1301 (58.7 %) were part of the medical school and 915 (41.3 %) were part of the affiliated radiology departments. Additionally, 1575 (71.1 %) were identified as men and 641 (28.9 %) as women. Rank biserial correlations showed a significant association between higher academic rank and male gender (rpb = 0.143, p < 0.001) regardless of affiliation (medical school leadership versus radiology faculty); this disparity was largest at the highest academic ranks. Male gender was associated with higher research productivity relative to female gender regardless of affiliation (p < 0.001). There were minimal statistical differences in leadership positions between genders, however the proportion of men holding the position of dean was two times higher than women.
    CONCLUSION: The underrepresentation of women in academic medicine is prevalent in the top-ranking medical institutions in North America and disproportionately involves senior academic ranks and leadership positions.
    Keywords:  Academic radiology; Gender disparity; Gender inequity; Leadership positions; Medical schools
    DOI:  https://doi.org/10.1067/j.cpradiol.2024.10.028
  53. Open Res Eur. 2024 ;4 191
      An unprecedented surge in digital payments has had a profound effect on the economic development of developing nations. This transition has enabled greater financial inclusion through the provision of banking services to populations that were previously marginalised. In addition, it has reduced reliance on physical currency, thereby improving security and transparency. This bibliometric analysis examines the research on digital payments in Malaysia and Poland, providing a comparative perspective on research patterns and contributions in these two countries. Furthermore, this study offers a comprehensive examination of the research environment in Malaysia and Poland, elucidating the distinct approaches, methodology, and areas of emphasis in each nation. These findings provide useful insights for those interested in championing digital payment initiatives, as well as contributing to a more robust and resilient digital payment framework. As digital payment ecosystems mature, their significance in altering the economic landscape of emerging countries is likely to become more evident in facilitating cross-border knowledge exchange and collaboration.
    Keywords:  Malaysia; Poland; VOSviewer; bibliometric analysis; digital payment
    DOI:  https://doi.org/10.12688/openreseurope.18248.1
  54. Sensors (Basel). 2024 Nov 06. pii: 7125. [Epub ahead of print]24(22):
      EEG-based Brain-Computer Interfaces (BCIs) have gained significant attention in rehabilitation due to their non-invasive, accessible ability to capture brain activity and restore neurological functions in patients with conditions such as stroke and spinal cord injuries. This study offers a comprehensive bibliometric analysis of global EEG-based BCI research in rehabilitation from 2013 to 2023. It focuses on primary research and review articles addressing technological innovations, effectiveness, and system advancements in clinical rehabilitation. Data were sourced from databases like Web of Science, and bibliometric tools (bibliometrix R) were used to analyze publication trends, geographic distribution, keyword co-occurrences, and collaboration networks. The results reveal a rapid increase in EEG-BCI research, peaking in 2022, with a primary focus on motor and sensory rehabilitation. EEG remains the most commonly used method, with significant contributions from Asia, Europe, and North America. Additionally, there is growing interest in applying BCIs to mental health, as well as integrating artificial intelligence (AI), particularly machine learning, to enhance system accuracy and adaptability. However, challenges remain, such as system inefficiencies and slow learning curves. These could be addressed by incorporating multi-modal approaches and advanced neuroimaging technologies. Further research is needed to validate the applicability of EEG-BCI advancements in both cognitive and motor rehabilitation, especially considering the high global prevalence of cerebrovascular diseases. To advance the field, expanding global participation, particularly in underrepresented regions like Latin America, is essential. Improving system efficiency through multi-modal approaches and AI integration is also critical. Ethical considerations, including data privacy, transparency, and equitable access to BCI technologies, must be prioritized to ensure the inclusive development and use of these technologies across diverse socioeconomic groups.
    Keywords:  Brain-Computer Interface (BCI); EEG-BCI trends; bibliometric analysis; cognitive rehabilitation; electroencephalography (EEG); motor rehabilitation; neurorehabilitation; rehabilitation
    DOI:  https://doi.org/10.3390/s24227125
  55. Front Artif Intell. 2024 ;7 1473872
       Introduction: The adoption of artificial intelligence (AI) in the workplace is changing the way organizations function, and profoundly affecting employees. These organizational changes raise crucial questions about the employee's future and well-being. Our study aims to explore the intersection between artificial intelligence and employee well-being through a bibliometric review and a contextual analysis.
    Methodology: Carried out in May 2024, our study is divided into two phases. The first phase, dedicated to bibliometric review, was conducted using the PRISMA method, and explored the Scopus and Web of Science databases for the period from 2015 to 2024. A total of 92 articles were selected for quantitative analysis using VOSviewer software. The second phase is based on an in-depth systematic analysis of 25 articles selected from those previously identified. These articles were selected on the basis of their relevance to the research question, and were subjected to in-depth thematic analysis using NVivo software.
    Results: The bibliometric analysis results reveal a significant increase in publications starting from the year 2020, highlighting advancements in research, primarily in the United States and China. The co-occurrence analysis identifies four main clusters: ethics, work autonomy, employee stress, and mental health, thus illustrating the dynamics created by artificial intelligence in the professional environment. Furthermore, the systematic analysis has brought to light theoretical gaps and under-explored areas, such as the need to conduct empirical studies in non-Western cultural contexts and among diverse target groups, including older adults, individuals of different sexes, people with low education levels, and participants from various sectors, including primary and secondary industries, small manufacturing businesses, call centers, as well as public and private healthcare sectors.
    Conclusion: Existing literature emphasize the importance for organizations to implement supportive strategies aimed at mitigating the potential adverse effects of AI on employee well-being, while also leveraging its benefits to enhance workplace autonomy and satisfaction and promote AI-enabled innovation through employee creativity and self-efficacy.
    Keywords:  artificial intelligence; bibliometric review; employee well-being; systematic review; workplace stress
    DOI:  https://doi.org/10.3389/frai.2024.1473872
  56. MycoKeys. 2024 ;110 273-285
      Journal impact factors were devised to qualify and compare university library holdings but are frequently repurposed for use in ranking applications, research papers, and even individual applicants in mycology and beyond. The widely held assumption that mycological studies published in journals with high impact factors add more to systematic mycology than studies published in journals without high impact factors nevertheless lacks evidential underpinning. The present study uses the species hypothesis system of the UNITE database for molecular identification of fungi and other eukaryotes to trace the publication history and impact factor of sequences uncovering new fungal species hypotheses. The data show that journal impact factors are poor predictors of discovery potential in systematic mycology. There is no clear relationship between journal impact factor and the discovery of new species hypotheses for the years 2000-2021. On the contrary, we found journals with low, and even no, impact factor to account for substantial parts of the species hypothesis landscape, often discovering new fungal taxa that are only later picked up by journals with high impact factors. Funding agencies and hiring committees that insist on upholding journal impact factors as a central funding and recruitment criterion in systematic mycology should consider using indicators such as research quality, productivity, outreach activities, review services for scientific journals, and teaching ability directly rather than using publication in high impact factor journals as a proxy for these indicators.
    Keywords:  Bibliometrics; impact factor; mycology; systematics; taxonomy
    DOI:  https://doi.org/10.3897/mycokeys.110.136048
  57. Scott Geogr J. 2024 ;140(3-4): 375-398
      This paper contributes to geographic literature on the effects of inequity in citational practice and politics, focusing in particular on onto-epistemological diversity (or lack thereof) in animal geographies' citational structures. Through a bibliometric analysis of journal articles in Anglophone animal geographies (as a subdiscipline of human geography), we examine the intersections between citational trends, the contours of knowledge in the field and everyday academic lives. Our goal in this paper is to highlight some of the ways in which citational inequities are fueled. Specifically, our analysis shows that within Anglophone animal geographies, citational esteem can accrue through institutional networks and shared onto-epistemologies, which often go along with ethical and political orientations that refrain from explicitly contesting the status-quo of anthropocentrism. We ground our analysis with a reflective discussion of everyday academic practice to understand the multi-scalar dynamics and implications of citational politics and prompt heightened reflexivity among geographers concerning how animal and other geographies are constructed and reproduced - and how these reproductions can be contested.
    Keywords:  Citation politics; animal geographies; anthropocentrism; diversity and inclusion; equity; onto-epistemological trends
    DOI:  https://doi.org/10.1080/14702541.2024.2374375
  58. Ecol Evol. 2024 Nov;14(11): e70614
      Bats exhibit a greater capacity to tolerate diverse viruses than other terrestrial mammals. To address these questions, we utilized evolutionary and bibliometric analyses to explore the immunological characteristics of bats and identify contemporary research hotspots in bat immunity. To investigate the historical interactions between bats and viral infections, we used tBLASTn software to identify the integrated endogenous retroviruses within the genomes of nine bat species and seven other mammals. To elucidate the immune characteristics of bats, we used the OrthoFinder, CAFE, and Gene Ontology analyses to identify the phylogenetic trees and homologous genes, expanded/contracted gene families, and associated signaling pathways of 28 mammalian genomes. We also used a bibliometric analysis of the "immune system of bats" to identify research hotspots and deepen our understanding of the immune mechanisms in bats. Significant integrations of Gammaretroviruses, Spumaretroviruses, and Deltaretroviruses were observed within bat genomes. Notable expansions in gene families included Type III interferon, heat-shock protein 90 (HSP90), and members of the tumor necrosis factor receptor superfamily (TNFRSF). These expanded gene families are involved in signaling pathways related to "transcription and replication of influenza virus RNA," "COVID-19-related pathways," and "positive regulation of protein phosphorylation." Notable contractions were observed in the "type I interferon" and "antibody-related gene families." Bibliometric analysis further underscored the several significance of critical immune genes, such as HSP90, Type I interferon, Type III interferon, and TNF. The exploration of research hotspots revealed two predominant themes: "efficient and varied antiviral responses" and "dampened inflammation to prevent excessive inflammatory reactions," thereby elucidating the mechanisms underlying the immune adaptations of bats. Through the evolutionary and bibliometric analyses, we identified several critical immune genes and signaling pathways related to bat immunity. Currently, research on the immune system of bats primarily focuses on the themes of "efficient antiviral responses" and "inflammation suppression."
    Keywords:  bats (Chiroptera); immune; scientometric analysis; visualization analysis
    DOI:  https://doi.org/10.1002/ece3.70614
  59. An Acad Bras Cienc. 2024 ;pii: S0001-37652024000701303. [Epub ahead of print]96(suppl 3): e20231178
      In 2000, the first draft of PhyloCode was made public, an alternative naming code that does not follow Linnaean rankings and is based on the phylogenetic relationships of taxa in cladograms. In this study, the impact of the PhyloCode on scientific literature was analyzed from its first appearance in the literature to 2021. We investigated the areas that have most assimilated the proposal, the criticisms that have arisen over time, and whether there has been growing adherence to it up to the present day. The analyzed data were obtained from the Clarivate Analytics Web of Science database, where 121 articles that used or discussed the PhyloCode were found. Initially, there was an increase in publications, but in mid-2004, there was a downward trend, which was more noticeable after 2008. Results suggest that despite the criticisms, the proposal has been used in research in several areas, mainly in Zoology and Botany, as an alternative to the Linnaean ranking system. Most articles have been published in Systematics and Taxonomy and discuss the functionality of the proposed code. Despite the proposal's potential, its acceptance can be considered relatively low and it still generates discussions, just like any scientific novelty.
    DOI:  https://doi.org/10.1590/0001-3765202420231178
  60. J Infect Public Health. 2024 Nov 15. pii: S1876-0341(24)00327-7. [Epub ahead of print]18(1): 102593
      The current study aims to identify research hotspots and trends in Monkeypox (MPX). A total of 2655 MPX-related articles published from 1961 to 2023 were extracted from the Scopus database. Data were analyzed using Scopus Analytics, Microsoft Excel, Bibliometrix, and VOSviewer. The number of MPX papers has been increasing annually, particularly since the most recent outbreak. The United States and India have been productive in this area. The most cited and productive scholar in the field is Inger K. Damon. The MPX research theme map shows clusters with various centralities and densities, focusing on deep learning, molecular docking, and orthopoxviruses. Over the last decade, key terms include "transmission," "pandemic," "deep learning," "docking," "Democratic Republic of Congo," "Ebola," "virulence," "modified vaccinia Ankara," and "orthopoxvirus." Researchers can utilize existing findings to steer future research on this illness, prepare for potential pandemics, and address bioterrorist threats.
    Keywords:  Bibliometrics; Knowloedge structure and dynamics; Monkeypox; VOSviewer program
    DOI:  https://doi.org/10.1016/j.jiph.2024.102593
  61. Regen Ther. 2024 Jun;26 1099-1116
      The introduction of three-dimensional (3D) printing scaffolds has emerged as an effective approach to achieving satisfactory revascularization for bone tissue engineering (BTE). However, there is a notable absence of analytical and descriptive investigations concerning the trajectory, essential research directions, current research scenario, pivotal investigative focuses, and forthcoming perspectives. Hence, the objective of this research is to offer a thorough overview of the advancements achieved in 3D printing structures for vascularized BTE within the last 10 years. Information extracted from the Web of Science repository spans from January 1, 2014, to April 1, 2024. Utilizing advanced analytical instruments, we conducted comprehensive scientometric and visual analyses. The findings underscore the predominant influence of China, representing 59.62 % of the overall publications and playing a pivotal role in shaping research within this field. Notable productivity was evident at various institutions, including Shanghai Jiao Tong University, Chinese Academy of Sciences, and Sichuan University. Wang Jinwu and Wu Chengtie stand out as the most prolific contributors in this domain. The highest number of publications in this area was contributed by the journal Advanced Healthcare Materials. In this study, osteogenesis imperfecta, osteosarcoma, fractures, osteonecrosis, and cartilage diseases were identified as the most significant disorders investigated in this research area. By providing a comprehensive scientometric assessment, this study benefits both experienced researchers and newcomers alike, offering prompt access to essential information and fostering the extraction of innovative concepts within this specific field.
    Keywords:  3D printing scaffolds; Angiogenesis; Bone tissue engineering; Scientometrics; Visualization analysis
    DOI:  https://doi.org/10.1016/j.reth.2024.10.013
  62. Urology. 2024 Nov 26. pii: S0090-4295(24)01087-2. [Epub ahead of print]
       OBJECTIVE: To identify the current rate of achieving publication and time to publication of abstracts presented at Societies for Pediatric Urology (SPU) meetings.
    METHODS: Fall SPU poster and podium presentations from 2017 - 2019 and 2021 were identified and reviewed for authorship (academic position), institutional (presence of pediatric urology fellowship), and publication (date of publication, journal, impact factor, and changes in authorship) details.
    RESULTS: Of the 688 abstracts presented at the annual fall SPU meeting, 311 (45.2%) were published, with an average time to publication of 12.3 months (standard deviation 10.8 months). The academic position of first authors was distributed among medical students (7.5%), residents (20.2%), fellows (28.5%), attendings (28.8%), and others (PhD, RN, etc.) (15%), while last authorship was dominated by attending physicians (90.2%). There were no significant author or institutional factors associated with achieving publication or time to publication. However, abstracts presented in 2021, after the cancelled 2020 meeting, were published in an average of 6.7 months, compared to 14.6 months from 2017-2019 (p < 0.001).
    CONCLUSIONS: While the annual SPU meeting is an important venue for presenting new information, the follow-through to publication is an area for improvement, which may limit dissemination of important new research. It does not appear that any author-specific factors or the affiliation with a fellowship program is associated with ultimate publication of presented abstracts.
    DOI:  https://doi.org/10.1016/j.urology.2024.11.040
  63. Acta Trop. 2024 Nov 26. pii: S0001-706X(24)00362-0. [Epub ahead of print] 107481
      The coronavirus disease 2019 pandemic highlighted the necessity and limitations of scientific collaboration and equitable and effective international research partnerships. The spread of mosquito-borne diseases (MBDs) presents severe public health challenges, particularly in Southeast Asia. Addressing these threats requires establishing regional priorities, bridging research gaps, and strengthening long-term international collaboration. We propose a practical approach to multifaceted perspectives to enhance collaboration across Asia. This study examines MBD-related scientific publications from nine Southeast Asian countries between January 2017 and June 2024, utilizing bibliometric analysis and data visualization to identify research trends, research capacities, key institutions, and international collaborative partners. Thailand and Singapore led the dengue research, followed by Malaysia and Indonesia. Vietnam and the Philippines demonstrated moderate research capabilities, whereas Cambodia, Laos, and Myanmar had lower capacities. Relationships with high-income countries drove international collaboration, whereas intra-regional collaboration in Southeast Asia increased. Furthermore, we identified directions for cooperative opportunities between South Korea and other Southeast Asian countries by analyzing their relative research capacities for infectious MBDs. We propose a practical approach to bridge research-capacity gaps and strengthen collaboration between low- and middle-income countries. These findings provide fundamental information for developing future infectious-disease-response strategies and international-collaboration research partnerships and facilitate the implementation of effective global public health preparedness policies and evidence-based decision-making, such as knowledge-transfer and resource-sharing.
    Keywords:  Collaboration; Mosquito-borne diseases; Practical Approach; Research Priority; South Korea; Southeast Asia
    DOI:  https://doi.org/10.1016/j.actatropica.2024.107481
  64. Gac Sanit. 2024 Nov 27. pii: S0213-9111(24)00090-6. [Epub ahead of print]38 102432
       OBJECTIVE: Understanding and targeting cancer stem cells (CSC) are areas of active research in oncology and further dissemination of scientific results is urgently needed to accelerate the comprehension of their involvement in tumor heterogeneity, resistance to conventional therapies and metastasis. In the context of open science, open access and data sharing, the aim of this study is to assess the current practices of cancer researchers in terms of publications and dissemination of research data.
    METHOD: A bibliometric study was conducted based on a bibliographic search using the Web of Science, and CSC articles with at least one Spanish affiliation were retrieved. A comparative study of the openness criteria of the journals was carried out, as well as an analysis of the associated data attached to the articles as supplementary material or deposited in repositories.
    RESULTS: 708 documents from 282 journals were retrieved. 303 articles contained associated research data, mostly published in Q1 journals, demonstrating a correlation between impact journals and their commitment to quality improvement. Supplementary material was the preferred method of data sharing, being pdf the most used file type. Only 69 articles mentioned datasets deposited in repositories, mainly from genomic nature. The main cancers studied were digestive and gastrointestinal, neurological, breast, hematological and respiratory, which coincided with the tumor types with the highest incidence and mortality, and in which the presence of CSC has been described.
    CONCLUSIONS: Researchers and publishers have become more aware of open science practices, but there is still a need for data quality according to the FAIR principles.
    Keywords:  Acceso abierto; Cancer stem cells; Ciencia abierta; Células madre cancerosas; Data sharing; Open access; Open science; Resistencia a terapias; Therapy resistance; Uso compartido de datos
    DOI:  https://doi.org/10.1016/j.gaceta.2024.102432
  65. Front Pharmacol. 2024 ;15 1498464
       Introduction: The use of infliximab to treat Crohn's disease patients has been evaluated for decades. The current work aimed to identify the historical roots of this research topic.
    Methods: The literature database Web of Science Core Collection was searched to identify relevant papers. Cited reference analysis on the identified literature set was performed using CRExplorer, a dedicated bibliometric software. The disruption index was computed with an automated routine described by Leydesdorff and Bornmann, which is freely available online. Based on data from citation count and reference list, the disruption index can range from -1 to +1, with -1 meaning a continuity from existing research and +1 meaning a disruption.
    Results: This analysis successfully identified key references dealing with infliximab use on Crohn's disease patients, such as the original report that introduced the Crohn's Disease Activity Index (CDAI) in 1976, the first case series reporting a favourable outcome of infliximab infusion on 10 patients published in 1995, the first randomized controlled trial published in 1997, the ACCENT I and ACCENT II trials published in 1999 and 2002, and a couple of European consensus guidelines on the diagnosis and management of Crohn's disease.
    Conclusion: Cited reference analysis could reveal the historical origins of the use of infliximab in treating Crohn's disease. Highly cited references included CDAI, important early clinical studies, and European consensus guidelines. The important cited references identified by the analysis provided solid foundation to support subsequent research.
    Keywords:  ACCENT I; CDAI; Crohn’s disease; cited reference analysis; infliximab
    DOI:  https://doi.org/10.3389/fphar.2024.1498464
  66. J Imaging. 2024 Oct 26. pii: 272. [Epub ahead of print]10(11):
      The application of image recognition techniques in the realm of cultural heritage represents a significant advancement in preservation and analysis. However, existing scholarship on this topic has largely concentrated on specific methodologies and narrow categories, leaving a notable gap in broader understanding. This study aims to address this deficiency through a thorough bibliometric analysis of the Web of Science (WoS) literature from 1995 to 2024, integrating both qualitative and quantitative approaches to elucidate the macro-level evolution of the field. Our analysis reveals that the integration of artificial intelligence, particularly deep learning, has significantly enhanced digital documentation, artifact identification, and overall cultural heritage management. Looking forward, it is imperative that research endeavors expand the application of these techniques into multidisciplinary domains, including ecological monitoring and social policy. Additionally, this paper examines non-invasive identification methods for material classification and damage detection, highlighting the role of advanced modeling in optimizing the management of heritage sites. The emergence of keywords such as 'ecosystem services', 'models', and 'energy' in the recent literature underscores a shift toward sustainable practices in cultural heritage conservation. This trend reflects a growing recognition of the interconnectedness between heritage preservation and environmental sciences. The heightened awareness of environmental crises has, in turn, spurred the development of image recognition technologies tailored for cultural heritage applications. Prospective research in this field is anticipated to witness rapid advancements, particularly in real-time monitoring and community engagement, leading to the creation of more holistic tools for heritage conservation.
    Keywords:  artificial intelligence; cultural heritage; deep learning; image recognition
    DOI:  https://doi.org/10.3390/jimaging10110272
  67. Cell Res. 2024 Nov 26.
    Cell Research Editorial Team
      
    DOI:  https://doi.org/10.1038/s41422-024-01056-6
  68. Cureus. 2024 Oct;16(10): e72569
      The National Resident Matching Program (NRMP), which is responsible for matching medical students with residency programs in the United States, quantifies an applicant's research by aggregating their total number of publications, presentations, and abstracts (PPA). However, the program does not differentiate between peer-reviewed publications, which are typically academic studies evaluated by peers in the field, and other types of research output. While several studies have examined the peer-reviewed publications of matriculants in specific specialties, none have compared these specialties to identify trends across the residency match. Comparing peer-reviewed publications across specialties helps the NRMP, medical schools, and applicants identify evolving research expectations and align efforts with specialty-specific benchmarks. Therefore, this scoping review aimed to comprehensively synthesize studies that investigated the peer-reviewed publications of matched medical students. A systematic literature search was performed in September 2023 to identify and extract bibliometric variables from studies analyzing the peer-reviewed publications of matriculated medical students. Of 164 articles screened, 18 studies across 10 specialties were included. Neurosurgery matriculants had the most publications (4.67), whereas ophthalmology had the least (1.23). The proportion of students with zero peer-reviewed publications at application ranged from 22% (neurosurgery) to 47% (orthopedic surgery) and decreased over time for orthopedic and plastic surgery. Publications increased over time for nearly all reported specialties. Higher publication quantity and author H-index were associated with matching into higher-tiered residency programs across all analyzed specialties. The quantity and quality of medical student peer-reviewed publications continue to increase, and higher quality and quantity are associated with matching into higher-tiered programs. Given these trends, medical schools/advisors should continue fostering research mentorship, and students should prioritize both research quantity and quality to optimally prepare for the match. Simultaneously, residency selection committees and policymakers should critically assess whether strong research backgrounds are an optimal method to stratify future physicians and whether there are other avenues to prevent a growing research arms race.
    Keywords:  bibliometric analyses; electronic residency applications; medical education; medical student research; residency match
    DOI:  https://doi.org/10.7759/cureus.72569
  69. Foods. 2024 Nov 07. pii: 3561. [Epub ahead of print]13(22):
      Global wine production has grown, resulting in an increase in waste within the industry. This has raised concerns among producers and scientists worldwide, prompting them to seek solutions for its management. The aim is to explore the latest advancements in using grape seed oil as a byproduct and its applications within the food industry. To achieve this, a bibliometric analysis was conducted using the Scopus database covering the period from 1990 to 2023. Additionally, a comprehensive literature review was conducted on extraction techniques, compositions, properties, and innovative applications in food. A bibliometric analysis revealed that interest in grape seed oil has grown over the past fifteen years. The majority of research on this grape byproduct is concentrated in Asian countries. Grape seed oil is a rich source of lipophilic compounds, including fatty acids, phytosterols, and vitamin E, which provide antioxidant and antimicrobial properties. The literature indicates that only oil obtained through pressing is used in food products, such as meat products, dairy drinks, and chocolates, either directly or in emulsions. These findings suggest that further research and innovation are needed to explore how this waste can be used in new food sources, particularly in countries with high wine production.
    Keywords:  Vitis vinifera; byproducts; food additive; traditional and alternative extraction methods; vegetable oil
    DOI:  https://doi.org/10.3390/foods13223561
  70. An Acad Bras Cienc. 2024 ;pii: S0001-37652024000601502. [Epub ahead of print]96(4): e20240340
      In this paper, we looked at the effect of mobility by students, post-doctorates and professors on science in Brazil. We analysed CAPES, CNPq, FAPESP and Incites data to examine the number of scholarships and their impact on posterior publishing. Decision trees, including the region of the country, length of stay by student and Professor, as well as institution abroad, were evaluated, along with logistic regressions. The number of incoming professionals to Brazil is still incipient. The number of undergrad students was not crucial in forming scientific ties, but the number of postgraduates (> 180 days) and professor stays (>90 days) was important. The highest impact factor of publications shows a greater probability of higher impact with more than six postgraduate students going to institutions in the global north region and professors staying for more than 90 days. Looking only at doctors and professors (Mobility after training), the country of most interest was the United States, followed by France and England, which are similar regarding professors. France had a greater emphasis on postdoctoral studies. Databases need to be improved to include factors such as gender and color/race as well as the origin of scholars from abroad.
    DOI:  https://doi.org/10.1590/0001-3765202420240340
  71. Front Immunol. 2024 ;15 1480596
      The study provides a thorough examination of literature from 2013 to 2023, delving into the intricate relationship between mitochondrial function and colorectal cancer (CRC). It offers a concise overview of the current landscape and emerging trends in this rapidly evolving research area. The findings indicate a consistent rise in annual publications, reflecting growing interest and significant potential in the field. China emerges as the leading contributor, followed by the United States and India. However, despite China's dominance in output, its average citation rate is lower than that of the US, which leads in citations per publication, highlighting a noticeable disparity. In the realm of research institutions, Shanghai Jiao Tong University and China Medical University are identified as major contributors, yet the potential for inter-institutional collaboration remains largely untapped, suggesting avenues for future synergy. Internationally, China-US collaborations are particularly robust, fostering cross-border knowledge exchange. Hyun Jin Won and Li Wei are recognized as prolific authors, while Ahmedin Jemal is an influential co-cited scholar, noted for his seminal contributions. Keyword analysis reveals research focus areas, such as the complex CRC tumor microenvironment, molecular mechanisms of oxidative stress, and key multidrug resistance pathways. It also highlights the promising potential of mitochondria-targeted therapies and nanomolecular technologies in clinical practice, signaling their growing significance in addressing complex health challenges. The study underscores the imperative to validate complex mitochondrial mechanisms and signaling pathways in CRC, with a particular emphasis on translating these insights into drug targets for clinical trials. Advancing this research is expected to refine and enhance CRC treatment strategies. Additionally, it highlights the urgency of validating mitochondrial complexities in CRC, advocating for collaborative efforts to link these mechanisms with tailored therapeutic interventions for clinical testing. This integrated approach promises significant advancements in developing effective, targeted CRC treatments, ultimately improving patient outcomes.
    Keywords:  apoptosis; colorectal cancer; mitochondria; mitochondrial metabolism; oxidative stress; tumor immunology; tumor microenvironment
    DOI:  https://doi.org/10.3389/fimmu.2024.1480596
  72. Arq Neuropsiquiatr. 2024 Nov;82(11): 1-11
       BACKGROUND:  Several studies have sought to investigate the trajectory of scholarly publications on dementia. Yet, there has been limited attention to contributions from Latin America.
    OBJECTIVE:  To provide a comprehensive overview of the literature output on dementia in Brazil.
    METHODS:  We conducted a Scopus-based literature search (2010-2021) for publications by authors affiliated with Brazil.
    RESULTS:  Out of 5,534 reports, 2,528 met the inclusion criteria. The annual growth rate of publications on dementia (9.9%, SD = 15.5) closely paralleled that of general health-related literature (6.7%, SD = 4.9). Most publications were categorized into the areas of diagnosis (33.4%) and disease mechanisms, origins, and models (32.7%). Epidemiological studies (4%), clinical trials (1%), and economic analyses (0.3%) are scarce. Based on the first affiliation of Brazil-affiliated authors, 89.3% of dementia output stemmed from Southeast (68.4%) and South (20.9%) of Brazil. Nonetheless, the state of São Paulo alone accounted for 41.1%, contributing to 60.1% of the Southeast. First and second authorships were predominantly held by female researchers, whereas male researchers occupied most of the second-to-last and last authorships. Overall, 1,812 (71.7%) were published in 346 foreign journals and 716 (28.3%) in 43 Brazilian journals. Notably, nearly half of the reports published in Brazil are concentrated in two journals: Dementia e Neuropsychologia (31.4%) and Arquivos de Neuro-Psiquiatria (15.2%).
    CONCLUSION:  There is a pressing need for more studies in dementia epidemiology and economic cost, in addition to more research across all Brazilian regions.
    DOI:  https://doi.org/10.1055/s-0044-1792095
  73. Dent Med Probl. 2024 Nov-Dec;61(6):61(6): 807-808
      The important thing is not to stop questioning. Curiosity has its own reason for existence. One cannot help but be in awe when he contemplates the mysteries of eternity, of life, of the marvelous structure of reality. It is enough if one tries merely to comprehend a little of this mystery each day.Albert Einstein.
    Keywords:  Dental and Medical Problems; Journal Impact Factor; article; citation; publication
    DOI:  https://doi.org/10.17219/dmp/194670
  74. World J Clin Cases. 2024 Nov 26. 12(33): 6655-6659
      By critically examining the work, we conducted a comprehensive bibliometric analysis on the role of nuclear factor erythroid 2-related factor 2 (NRF2) in nervous system diseases. We also proposed suggestions for future bibliometric studies, including the integration of multiple websites, analytical tools, and analytical approaches, The findings presented provide compelling evidence that ferroptosis is closely associated with the therapeutic challenges of nervous system diseases. Targeted modulation of NRF2 to regulate ferroptosis holds substantial potential for effectively treating these diseases. Future NRF2-related research should not only focus on discovering new drugs but also on designing rational drug delivery systems. In particular, nanocarriers offer substantial potential for facilitating the clinical translation of NRF2 research and addressing existing issues related to NRF2-related drugs.
    Keywords:  Bibliometric; Ferroptosis; Nervous system diseases; Nuclear factor erythroid 2-related factor 2; Target
    DOI:  https://doi.org/10.12998/wjcc.v12.i33.6655
  75. Curr Probl Diagn Radiol. 2025 Jan-Feb;54(1):pii: S0363-0188(24)00198-1. [Epub ahead of print]54(1): 97-101
      Despite women's early involvement in and contributions to the field of radiology, such as Marie Curie's work in radiation physics and chemistry, women have long remained lacking in their representation among radiologists, including in academics. While many other medical specialties have gradually become more proportionate or even equalized in their gender distribution, radiology continues to exist as a predominately male specialty. In this special topics issue, we aim to explore the landscape of female representation in academic radiology over time, not only in number, but in research productivity, recognition and accolades, and grant and funding reception. We discuss the progress that has been made and factors that have influenced that progress, as well as the crucial role that women currently hold in the field of academic radiology.
    Keywords:  Academic Radiology; Education; Gender
    DOI:  https://doi.org/10.1067/j.cpradiol.2024.10.029
  76. BMC Oral Health. 2024 Nov 23. 24(1): 1431
       BACKGROUND: Open Science Practices (OSPs) are essential when assessing research integrity and quality of Randomised Clinical Trials (RCTs). As dental caries represents a significant oral health burden, our objective was to identify and analyse the adoption of OSPs within RCTs focused on addressing this disease.
    METHODS: We searched PubMed to retrieve RCTs related to dental caries published from January 2000 to March 2022. Two independent researchers assessed a random sample of these articles to evaluate their eligibility until reaching the minimum sample size. Then, the same examiners reviewed the included texts regarding the OSPs adopted in the articles. The collected variables related to OSPs were reporting guidelines, protocol registration, detailed methodology available, open-source software, statistical analysis code sharing, statistical analysis plan, data sharing, open peer review, and open access. Association analyses using logistic regression were conducted considering the publication year, the continent of the first author, impact factor and open-access policy of the journals (explanatory variables), and adoption of at least one OSP or one OSP other than open access (outcomes). The recommendations for adopting OSPs were assessed by reviewing the "Instructions for Authors" section of the most frequently used journals where the included papers were published.
    RESULTS: 64.8% of the articles (95% Confidence Interval = 59.3-70.1%) adopted at least one OSP. However, no individual OSP was adopted by more than 50% of the articles. The most adopted practices were protocol registration (37.1%), the use of reporting guidelines (33.1%) and publishing open access (37.3%). These are also the OSPs most often recommended by journals in the Instructions for Authors. A few articles adopted other practices. Older articles presented a lower frequency of adopting these practices, and articles published in higher impact factor journals were positively associated with both outcomes.
    CONCLUSION: The RCTs published on dental caries demonstrate a low frequency of adoption of most OSPs. However, a trend toward increased adoption of these practices has been notable in recent years.
    Keywords:  Data sharing; Dental caries; Open access; Open science; Randomized clinical trials; Research integrity
    DOI:  https://doi.org/10.1186/s12903-024-05218-1
  77. Dent Clin North Am. 2025 Jan;pii: S0011-8532(24)00054-5. [Epub ahead of print]69(1): 29-38
      Dentistry has traditionally been male-dominated in North America, although "primary care" dentistry disciplines, including dental public health (DPH), have greater gender equity than other areas. However, gender gaps are likely to persist, specifically in academia. As an example of the measurement of inclusion, we sought to identify gender equity in authorship in publications in DPH and epidemiology over six years. We found that while women occupied first and second authorship positions, men dominated the senior author position. Evaluating gender in authorship provides valuable information on inclusion and the movement toward achieving gender equity in dental public health.
    Keywords:  Dentistry; Diversity; Equity; Gender; Inclusion; Men; United States; Women
    DOI:  https://doi.org/10.1016/j.cden.2024.08.002
  78. Zhonghua Kou Qiang Yi Xue Za Zhi. 2024 Nov 21. 59(12): 1185-1193
      Chinese Journal of Stomatology has had eighty papers on Chinese stomatology history issued for seventy years. According to three stages of the journal,statistics of the quantity and themes of the issued papers are compiled: the number of issued papers increases while the theme shifts from Chinese stomatology history before 1912 to Chinese contemporary stomatology history. Research methods shifts from the comparatively scanty approach of summary and induction on literature and cultural relics materials to multidisciplinary approaches. Early researches saw the senior scholars such as Zhou Dacheng and Mao Xiejun play the role in the field while recent years research teams represented by colleges and research institutions have published varied research topics. As the research deepens, platforms for issuing stomatology papers have been expanded, more subjects have been cross-disciplined and some academic monographs on stomatology history and stomatology education history have been published, among which Zhou Dacheng's Historic textual research of Chinese stomatology can be regarded as a milestone in the field. Comparing with other fields in the stomatology, current research on stomatology history still has much more gap to fill. The academic community should put more emphasis on talent training, discipline construction, research approaches, museum construction and cooperation between Chinese and western medical sciences so that to assist in the long-term development of the research.
    DOI:  https://doi.org/10.3760/cma.j.cn112144-20241023-00395
  79. Foods. 2024 Nov 11. pii: 3607. [Epub ahead of print]13(22):
      The United Arab Emirates (UAE) faces obstacles in guaranteeing food security because of its desert climate, restricted arable land, and significant reliance on food imports. Establishing a robust and transparent food supply chain is crucial. This study investigates the crucial functions of blockchain technology in protecting and improving food security in the UAE. Using bibliographic and co-citation network analyses, this study examines 143 research articles that provide a thorough review of the current status of blockchain technology in relation to food security. We examine the interrelationships among studies, highlighting significant themes and identifying three emerging food security patterns in the incorporation of blockchain into the food security domain. This study enhances the understanding of how blockchain technology can transform the food security dimensions of availability, accessibility, utilization, and stability in the UAE and worldwide.
    Keywords:  blockchain; food security; food supply chain; food trust; literature review
    DOI:  https://doi.org/10.3390/foods13223607