bims-evares Biomed News
on Evaluation of research
Issue of 2024–11–24
77 papers selected by
Thomas Krichel, Open Library Society
  1. Essential Reads in Rhinology: A Bibliometric Analysis.
  2. Bibliometric analysis of microphthalmos and anophthalmos over 20 years: from 2004 to 2023.
  3. Bibliometric analysis of the Acta Orthopaedica et Traumatologica Turcica from 2013 to 2022.
  4. The 100 most-cited articles in hypothermic brain protection journals: a bibliometric and visualized analysis.
  5. A Study of Citations: Bibliometric Analysis of the 100 Top-cited Publications on Panic Disorder.
  6. Research trends of acupressure from 2004 to 2024: A bibliometric and visualization analysis.
  7. Mapping the Health and Medical Research Excellence in Nepal: A Study of High-Cited Papers During 1994-2023.
  8. A Comprehensive Bibliometric Analysis and Visualization of Publication Trends in Hip-Spine Syndrome.
  9. Top 100 most cited economic evaluation papers of preventive oral health programmes: A bibliometric analysis.
  10. Spiritual Leadership Research: Past, Present and Future Using Bibliometric Analysis.
  11. Visualize the time dynamics and research trends of macrophage associated periodontitis research from 2004 to 2023: Bibliometrix analysis.
  12. Global research landscape on antiphospholipid syndrome and systemic lupus erythematosus: Trends, collaborations, and future directions.
  13. Knowledge domain and trends in treatment-resistant schizophrenia (TRS) research based on CiteSpace bibliometrics analysis.
  14. Bibliometric and visualized analysis of 2014-2024 publications on therapy for diabetic peripheral neuropathy.
  15. Global trends and biological activity hotspots of D-limonene in essential oils: a 30-year bibliometric study.
  16. Focuses and Trends of Research on Platelet-Rich Fibrin: A Bibliometric and Visual Analysis.
  17. Research Hotspots and Trends in Global Cancer immunometabolism:A Bibliometric Analysis from 2000 to 2023.
  18. Immune checkpoint inhibitors: A bibliometric analysis of research trends and hotspots based on the most frequently cited clinical trials (2013 - 2021).
  19. Advancing understanding of autoimmune disease-related interstitial lung disease (AD-ILD): A global perspective on research focus and future directions.
  20. Panaroma of microglia in traumatic brain injury: a bibliometric analysis and visualization study during 2000-2023.
  21. Research frontiers and hotspots of coronary chronic total occlusion: A bibliometric analysis.
  22. Global trends and prospects related to macrophage in chronic kidney disease: a bibliometric analysis.
  23. Platelet-rich plasma: A bibliometric and visual analysis from 2000 to 2022.
  24. Worldwide Research Trends and Regional Differences in the Development of Precision Medicine Under Data-Driven Approach: A Bibliometric Analysis.
  25. Scientific Research Trend on Guided Tissue Regeneration: A Bibliometric Analysis.
  26. Research-Oriented Hospitals in China: A Bibliometric and Visualization Analysis Based CiteSpace.
  27. Research hotspots and trends related to pain in gouty arthritis from 2014 to 2024: A bibliometric analysis.
  28. Near-infrared spectroscopy in schizophrenia: A bibliometric perspective.
  29. Objective assessment of cognitive fatigue: a bibliometric analysis.
  30. Bibliometric analysis of scholarly publications related to family medicine in Thailand.
  31. Frontiers and hotspots evolution between air pollution and Alzheimer's disease: A bibliometric analysis from 2013 to 2023.
  32. Impact of scientific production of Italian scientists in exercises and sport sciences by measuring the author-weighted h-index.
  33. Global Trends and Perspectives on Dental Fragment Reattachment (1988-2024): A Bibliometric and Altmetric Review.
  34. Radiomics in precision medicine for colorectal cancer: a bibliometric analysis (2013-2023).
  35. Gender differences in representation, citations, and h-index: An empirical examination of the field of communication across the ten most productive countries.
  36. Mapping the scientific landscape and evolution of the international journal of surgery: A scientometric analysis (2004-2024).
  37. Natural mortality of fish: a review.
  38. Current status and hotspots in breast cancer patient self-management research: A bibliometric and visual analysis via CiteSpace.
  39. Comments on "Extraction, purification, characteristics, bioactivities, prospects, and toxicity of Lilium spp. polysaccharides by Li et al. (2024) in Int. J. Biol. Macromol."
  40. Artificial intelligence and big data from digital health applications: publication trends and analysis.
  41. A bibliometric study on clinical research in neonatal encephalopathy.
  42. Thematic trends and knowledge-map of tumor-infiltrating lymphocytes in breast cancer: a scientometric analysis.
  43. Bibliometric analysis of olaparib and pancreatic cancer from 2009 to 2022: A global perspective.
  44. Current Status and Global Research Trend Patterns of Insect Meal in Aquaculture From Scientometric Perspective: (2013-2022).
  45. Research focus and emerging trends of cancer-related fatigue in nursing arena: A bibliometric analysis from 2012 to 2021.
  46. Association of Unsafe Sexual Behavior with Head and Neck Cancer: A Bibliometric Analysis.
  47. Research on the global trends of COVID-19 associated acute kidney injury: an updated bibliometric analysis.
  48. Targeting ferroptosis reveals a new strategy for breast cancer treatment: a bibliometric study.
  49. What Are the Research Highlights of Periprosthetic Joint Infections From the 100 Most Cited Studies?
  50. From Thesis to Publication: Unveiling the Predictive Factors for Cardiology Research at a North African Faculty of Medicine (Tunisia).
  51. Debate on the relationship between Helicobacter pylori infection and inflammatory bowel disease: a bibliometric analysis.
  52. Yoga in Cancer Care: A Bibliometric Analysis of Systematic Reviews.
  53. Gender Disparity in Surgical Research: An Analysis of Authorship in Randomized Controlled Trials.
  54. Mapping epilepsy biomarkers: a bibliometric and content analysis.
  55. Global Trends of Mechanical Thrombectomy in Acute Ischemic Stroke Over the Past Decade: A Scientometric Analysis Based on WOSCC and GBD Database.
  56. A vivid study on corporate social responsibility and its internal perception: Bibliometric analysis approach.
  57. Survival Analysis of Glioblastoma: A Scientometric Perspective.
  58. Delusional Procreation Syndrome: A Citation Analysis and Review from the First 12 Years of Publication.
  59. Conilon coffee: A critical review and bibliometric analysis for the agri-food industry.
  60. Diversity in the editorial boards of medical journals: a perspective from the Middle East.
  61. Authorship and publication trends in the congenital hand surgery literature.
  62. Bridging the gap: advancing gender equality in medical research.
  63. Reply to "Refining search and keyword strategies in autoimmune ear disease bibliometric studies".
  64. Identifying the Next Generation of Academic Surgeons and Physician Leaders.
  65. Women authors in the first 50 years of DGE-contributions and research topics.
  66. A review of advancements in the theory and characterization of soil macropore structure.
  67. Strategic interventions in clinical randomized trials for metabolic dysfunction-associated steatotic liver disease (MASLD) and obesity in the pediatric population: a systematic review with meta-analysis and bibliometric analysis.
  68. "Dental and Medical Problems": Where we are and where we are going.
  69. Bibliometric analysis of myelomeningocele management: National disease burden versus publication volume.
  70. The Evolution of Calcium Alginate-Based Dressings in Wound Healing: A Comprehensive Bibliometric Review of the Top 100 Cited Studies.
  71. Oncofertility Research: A Review of the Literature.
  72. Leading Nature Index science cities in biological sciences: collaboration powers US research.
  73. Leading Nature Index science cities in Earth and environmental science: Research output gathers pace in China.
  74. Research trends, hotspots and future directions of tertiary lymphoid structures in cancer: a comprehensive informatics analysis and visualization study.
  75. Open-access journal eLife to lose 'impact factor'.
  76. China and the U.S. produce more impactful AI research when collaborating together.
  77. Half of the top 20 science cities are now in China - and regional city growth is the key.
  1. Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6): 5652-5665
    Essential Reads in Rhinology: A Bibliometric Analysis.
    Ariana L Shaari, Shreya Bhalla, Rebecca Ho, Anup Dupaguntla, Sylvia Zabielski, Wayne Hsueh, Jean Anderson Eloy, Andrey Filimonov.
       Aims: Rhinology is a progressive subspecialty within otolaryngology. Bibliometric analysis is a powerful method to survey the landscape of literature on a specific topic and identify publication trends. We aimed to analyze the 50 most impactful English-language rhinology manuscripts of all time to create a targeted reading list for otolaryngologists.
    Material and Methods: The Journal Citation Report within the Web of Science database was utilized to identify articles relating to rhinology. Web of Science Research categories were restricted to otolaryngology. The articles were then ranked by number of citations. The top 50 articles of all time ranked by number of citations were analyzed. The articles were analyzed for publication year, journal impact factor, citation density, first author (FA), and senior author (SA) name, country, and institution. Statistical analyses were performed.
    Results: Most articles were published in the 2000s (N = 22, 44%) and 1990s (N = 11, 22%). Male FA (N = 37, 74%) and SA (N = 43, 86%) published most articles. Most articles were clinical studies (N = 36, 72%) followed by clinical guidelines/expert opinions. Most articles were published in the United States (N = 28, 56%) and England (N = 9, 18%). There were more female FAs of guidelines/position papers than basic lab, reviews, and clinical studies. England had more female FAs than other countries, and the United States had more female SA. There was an average of 585.2 citations per study.
    Conclusion: This investigation highlights the most influential literature within rhinology. The most impactful studies are consensus statements, large multicenter studies, and technique studies. Significant gender disparities in authorship exist.
    Keywords:  Bibliometric analysis; Gender disparities; Otolaryngology; Rhinology; Surgical education
    DOI:  https://doi.org/10.1007/s12070-024-05055-2
  2. Int J Ophthalmol. 2024 ;17(11): 2120-2128
    Bibliometric analysis of microphthalmos and anophthalmos over 20 years: from 2004 to 2023.
    Ming-Hui Wang, Gong-Fei Li, Ju Zhang.
       AIM: To conduct a bibliometric analysis of studies on microphthalmos and anophthalmos (M/A), explore research hotspots, and provide information on future research interests in this field to benefit clinicians and researchers.
    METHODS: Totally 751 publications related to M/A from the year 2004 to 2023 were collected from the Web of Science Core Collection database. These publications consist of both original and review articles, that are composed in English. The contributions of different countries, institutions, journals, and authors were analyzed, and network analysis was conducted by using Microsoft Excel 2021, VOSviewer, and R Studio to visualize research hotspots.
    RESULTS: Among all publications included, the highest number of publications came from USA (218, 29.03%). China followed with 99 publications (13.18%), and England with 86 publications (11.45%). The publications from the USA had the highest frequency of citations, with 16 699 citations, and the highest H-index of 49. The American Journal of Medical Genetics Part A (43, 5.73%) published the largest number of papers, and the University of London had the most publications (41, 5.46%). The genetic and molecular mechanisms of M/A were still unclear and the clinical intervention for M/A had gained a lot of attention as an emerging area of interest.
    CONCLUSION: Data have been gathered on the yearly count of published materials and citations, as well as the rise in publication trends, the efficiency of regions or countries, authors, journals, and organizations, along with the high-cited publications in M/A. The recent trend of research has shifted from genetic mechanisms to different clinical phenotypes and corresponding clinical interventions, which can give direction to future research.
    Keywords:  anophthalmos; bibliometric analysis; microphthalmos; network analysis
    DOI:  https://doi.org/10.18240/ijo.2024.11.19
  3. Acta Orthop Traumatol Turc. 2024 Nov 08. 58(5): 255-262
    Bibliometric analysis of the Acta Orthopaedica et Traumatologica Turcica from 2013 to 2022.
    Necmettin Turgut, Salih Beyaz.
       Objective: This study aimed to analyze the original articles published in Acta Orthopaedica et Traumatologica Turcica (AOTT) between 2013 and 2022 using bibliometric methods to identify their characteristics and examine the changing trends over the last 10 years.
    Methods: The articles were analyzed in terms of publication year, authors, countries, affiliations, citations, study design, subspecialty of orthopedics, sample size, study outcome, presence of statistical methods, time elapsed from submission date to acceptance date, and presence of funding. Periods (2003-2012 and 2013-2022) were compared for trend analysis in the journal. Advanced bibliometric analysis was done using VOSviewer software (version 1.6.19).
    Results: A total of 976 articles were included in the analysis. The journal's self-citation rate was 2.94%. Retrospective observational studies remained the most frequently published article design, as observed over 2003-2012 (n=411, 42.1%). No review articles were published in the previous period, while 35 review articles were published in this period. Publications from countries outside Türkiye exhibited a significantly higher number of case reports and reviews (P = .001), whereas articles from Türkiye had a significantly greater number of basic science and cross-sectional studies (P = .007, P=.017, respectively). Trauma (n=207), general orthopedics (n=144), and spine (n=105) were identified as the most prominent subspecialties. Spine surgery and adult reconstruction/arthroplasty publications significantly increased, while hand and microsurgery publications significantly decreased (P < .001). Article types were compared regarding citation counts, revealing that case reports and technical notes had significantly lower citation counts (P = .001). There was a significant increase observed in the number of author affiliations (n=2.57 ± 1.40) (P < .001). Management" (n=83), "fixation" (n=78), and "surgery" (n=65) were the most occurring keywords. There was a significant increase in articles with 1 or 2 authors in the latter 2017-2022 period compared to 2013-2016 (P=.001). A significant increase was observed in publications from private clinics and other clinical facilities (P < .001).
    Conclusion: Acta Orthopaedica et Traumatologica Turcica (AOTT) has emerged as one of the leading journals in orthopedics, with a notable increase in international publications in the last decade. Being in the Science Citation Index Expanded (SCI-Expanded) database, increasing impact factor, and having low self-citation rates highlight its high standards and global impact. Acta Orthopaedica et Traumatologica Turcica (AOTT) is a valuable platform for researchers worldwide to share their work and advance orthopedic knowledge.
    Level of Evidence: N/A.
    Keywords:  General orthopaedics; Joint replacement surgery; Orthopaedic trauma; Orthopaedics and traumatology; Physical medicine and rehabilitation
    DOI:  https://doi.org/10.5152/j.aott.2024.23172
  4. Front Neurol. 2024 ;15 1433025
    The 100 most-cited articles in hypothermic brain protection journals: a bibliometric and visualized analysis.
    Liren Hu, Sirui Geli, Feiyu Long, Liang Nie, Jiali Wu, Jun Zhou, Maohua Wang, Yingxu Chen.
       Introduction: A bibliometric analysis is used to assess the impact of research in a particular field. However, a specialized bibliometric analysis focused on hypothermic brain protection has not yet been conducted. This study aimed to identify the 100 most-cited articles published in the field of hypothermic brain protection and analyze their bibliometric characteristics.
    Methods: After screening articles from the Web of Science citation database, complete bibliographic records were imported into Python for data extraction. The following parameters were analyzed: title, author's name and affiliation, country, publication year, publication date, first author, corresponding author, study design, language, number of citations, journal impact factors, keywords, Keywords Plus®, and research topic.
    Results: The 100 articles were published between 1990 and 2016. The citation frequency for each publication ranged from 86 to 470. Among the 100 articles, 73 were original articles, 18 were review articles, 8 were clinical articles, and 1 was editorial material. These papers were published in 37 journals, with the Journal of Cerebral Blood Flow and Metabolism being the most prolific with 15 papers. Eighteen countries contributed to the 100 publications, 51 of which were from United States institutions. In addition, the keywords in the Sankey plot indicated that research in the field of hypothermic brain protection is growing deeper and overlapping with other disciplines.
    Discussion: The results provide an overview of research on hypothermic brain protection, which may help researchers better understand classical research, historical developments, and new discoveries, as well as providing ideas for future research.
    Keywords:  bibliometric analysis; brain protection; citations highlights; hypothermia; surgery
    DOI:  https://doi.org/10.3389/fneur.2024.1433025
  5. Indian J Psychol Med. 2024 Aug 04. 02537176241259143
    A Study of Citations: Bibliometric Analysis of the 100 Top-cited Publications on Panic Disorder.
    Gayatri Bhatia, Vrinda Kabra, Anureet Kaur Chandi, Rahul Mathur.
       Background: The number of times a publication is cited in scientific research papers is often considered to estimate its contribution to biomedical literature. Although extensive research has been conducted on panic disorder over time, attempts at a citation analysis have yet to be made to the best of our knowledge.
    Aim: The aim of this study was to understand the trends of research on panic disorder from the top 100 most-cited publications worldwide.
    Materials and Methods: A citation analysis of the top 100 panic disorder publications was conducted, using Harzing's Publish or Perish to identify articles from Google Scholar. The study analyzed citation patterns, authorship, publication types, and themes. Exclusions comprised non-scientific materials. No ethics approval was needed as it involved published data, not human subjects.
    Results: Publications with more than 500 citations were 11, and those with more than 400 citations, known as citation classics, were 27. Fifty-nine publications were funded, of which 14 (23.8%) were clinical trials and 24 (40.7%) were observational studies. The maximum number of articles was published between 1990 and 1999 (n = 45), followed by 2000 and 2009 (n = 26). The h-index of the first author showed a significant positive correlation with the number of citations of the paper (Spearman's ρ = 0.480, P = 0.02). Among research papers, the maximum were observational studies (n = 44), followed by 19 randomized controlled trials (RCTs) and eight non-randomized clinical trials. Additionally, among RCTs (n = 19), 17 were focused on the management theme.
    Conclusion: This bibliometric analysis is an invaluable resource for scholars and students who might be interested in learning about the developments and patterns in the field of panic disorder research.
    Keywords:  Anxiety; citation classics; panic disorder; publications
    DOI:  https://doi.org/10.1177/02537176241259143
  6. Heliyon. 2024 Nov 15. 10(21): e38675
    Research trends of acupressure from 2004 to 2024: A bibliometric and visualization analysis.
    Zhi-Qiang Li, Mary Yue Jiang, Xue-Han Liu, Yi-Qing Cai, Chen-Lu Wang, Feng Cao, Jian-Ping Liu.
       Background: Acupressure has proven efficacy in symptoms management, making it valuable in clinical practice and patient care. Given the rising number of increasing publications on acupressure, we aimed to analyze the literature from the past 20 years and provided current trends and hotspot for future research directions.
    Methods: Publications on acupressure from January 1, 2004 through May 1, 2024 were retrieved from the Web of Science database. The extracted records underwent thorough analysis based on publication year, research area, journal, countries/regions, organization, authors, and keywords. The bibliometric analysis was conducted using Citespace and Microsoft Excel software.
    Results: Of the 1,929 screened records, 770 publications were identified. The annual number of acupressure has gradually increased, with the 45 % of the total publication occurring from 2020 to 2024. Among countries and institutions, China (252 articles) and Hong Kong Polytechnic University (41 articles) have the highest number of publications. Notably, USA and Hong Kong Polytechnic University exhibits the highest centrality score in cooperative network among countries/regions and institutions. Chao Hsing Yeh from the Cizik School of Nursing, University of Texas Health Science Center, was the most prolific author with 22 papers. Evidence-Based Comple Alt, with 53 articles, is the journal with the most publications. According to the keyword, timeline diagram and prominence mapping analysis, we believe that "insomnia", "labor", "waist circumference", "reliability" and "vagus nerve stimulation" related clusters may be new hotspots in the field of acupressure.
    Conclusion: This study presents the research trajectory of acupressure over the past 20 years, providing a foundation for future research and highlighting the significant contributions of nursing researchers. By analyzing research trends and hotsport, nursing professionals can integrate acupressure more effectively into holistic patient care, improving quality of life, and contributing to traditional Chinese medicine.
    Keywords:  Acupressure; Bibliometrics; Hot spot; Nursing; Research trends
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e38675
  7. J Nepal Health Res Counc. 2024 Oct 03. 22(2): 213-225
    Mapping the Health and Medical Research Excellence in Nepal: A Study of High-Cited Papers During 1994-2023.
    Raju Vaishya, Brij Mohan Gupta, Ghouse Modin Nabeesab Mamdapur, Ali K S, Abhishek Vaish, Pramod Joshi, Pawan Kumar Hamal.
       BACKGROUND: A bibliometric analysis was performed to map the current status and development trends in medical research in Nepal. It aims to visualize research hotspots within this field and provide effective guidance for future research directions.
    METHODS: A systematic search of the Scopus database was performed to identify high-cited papers (HCPs) on medical research in Nepal between January 1, 1994, and December 31, 2023. Bibliometrics techniques were applied to analyze the publication dates, countries, institutions, journals, authors, and research hotspots. Statistical analysis and visualization were carried output by MS-Excel and VOSviewer software.
    RESULTS: A total of 326 HCPs were identified that have received 100 to 10719 citations and registered 223.05 Citations Per Paper (CPP). The 47.54% and 95.40% share of the 326 HCPs have received external funding support and are involved in international collaboration, respectively. The 15892 (417 from Nepal) authors, affiliated to 12830 (177 from Nepal) organizations and published in 138 journals participated in 326 HCPs from Nepal. USA (60.45% share) and India. (51.45% share) were the most collaborative countries, while Spain (1609.15 CPP) and Mexico (1597.08 CPP) made the largest citation impact in collaboration with Nepal. C.L. Ranabhat (n=27) and B. Sathian (n=26) were the most productive authors, while D. Acharya (3652.29 and 16.5), and S. Bhattarai (2880.11 and 13.01) registered the highest citation impact (CPP and RCI). Tribhuvan University, Kathmandu (n=72) and Nepal Health Research Council, Kathmandu (n=34) were the most productive organizations, while Kathmandu University (3652.29 and 16.5) and Nepal Academy of Science and Technology, Lalitpur (2941.67 and 13.29) registered the highest citation impact (CPP and RCI). The Lancet (n=75) and British Medical Journal (n=11) were the most productive journals, while The Lancet Neurology (1749.5 CPP), and The Lancet (1371.13 CPP) registered the highest average citations impact. B. Basnyat has the most citation as first author in health and medical research.
    CONCLUSIONS: The present study offers an overview of research characteristics and trends of medical research output in Nepal. It identifies main contributors, core journals, and significant subject topics. The study hopes to assist researchers and practitioners in comprehending the development and trends of medical research in Nepal and discovering potential directions for future research.
    Keywords:  Bibliometric methods; citations; collaboration; high-cited papers; medical research.
    DOI:  https://doi.org/10.33314/jnhrc.v22i02.5225
  8. World Neurosurg. 2024 Nov 20. pii: S1878-8750(24)01899-0. [Epub ahead of print]
    A Comprehensive Bibliometric Analysis and Visualization of Publication Trends in Hip-Spine Syndrome.
    Hanmo Fang, Min Cui, Zhiming Zhao, Yong Feng, Xianlin Zeng, Cao Yang, Lin Xie.
       STUDY DESIGN: Bibliometric analysis.
    OBJECTIVE: Hip-Spine Syndrome (HSS) was first described in 1983 as a syndrome characterizing the concurrent symptoms of lumbar and hip joint degenerative disease. This study aims to elucidate the research trends, hot topics, and influential publications in HSS through bibliometric analysis.
    METHODS: The Web of Science database was used to search for all literature on HSS from 1983 to 2024. VOSviewer, CiteSpace and Scimago Graphica software were employed to analyze the data and generate visual knowledge maps. Analyses included annual publication trends, keywords, authors, citation bursts, co-citation situations, and research clustering hotspots.
    RESULTS: Of the 236 publications meeting the inclusion criteria, the volume on HSS has steadily increased over the past forty years. The United States leads in publication volume, followed by Australia and Japan. Total hip arthroplasty (THA), clinical significance, and disease classification have emerged as frontiers and hotspots. The journals with the highest publication volumes are the Journal of Arthroplasty, Spine, and European Spine Journal. Key papers have been identified as foundational works in the field. However, international, institutional and authorial collaboration remains limited.
    CONCLUSION: Over the past four decades, the volume of publications on HSS has steadily increased. The United States leads both in the quality and quantity of published articles. The most influential works have enhanced our understanding of the pathogenesis and surgical decision-making in HSS. This study provides a comprehensive review of the trends and influential research in HSS.
    Keywords:  Hip-Spine Syndrome; bibliometric analysis; research trends; visualization
    DOI:  https://doi.org/10.1016/j.wneu.2024.11.039
  9. J Oral Biol Craniofac Res. 2024 Nov-Dec;14(6):14(6): 802-807
    Top 100 most cited economic evaluation papers of preventive oral health programmes: A bibliometric analysis.
    Lekshmi Anand, P Gayathri, Vineetha Karuveettil, M Anjali.
       Objective: To identify the trends of the top 100 cited articles on economic evaluation in preventive oral health programs.
    Methods: Top 100 papers involving economic evaluation or cost analysis of preventive oral health programs were selected by querying Scopus and Web of Science databases. Bibliometric analysis was performed using the Bibliometrix tool in R Studio. Performance analysis and science mapping were performed for these 100 articles. Performance analysis included publication-related metrics, citation-related metrics, and citation-publication-related metrics. Science mapping provided information on citation analysis, co-citation analysis, bibliographic coupling, co-word analysis, and co-authorship details.
    Results: The total citation number of the top 100 most cited articles ranged from 4 to 98, with publication dates spanning from 1978 to 2023. The majority of articles (33.70 %) originated from the USA, while Community Dentistry and Oral Epidemiology stood out as the journal with the highest number of articles published in the top 100 (16 out of 100). Griffin PM emerged as the most cited author, based on the frequency measurement of the number of papers. Program data economic evaluation was the most commonly reported study design, and fluoridation programs were the most frequent topic. The most reported type of economic analysis performed in the articles was cost-effectiveness analysis.
    Conclusion: The bibliometric analysis of the top 100 most-cited articles on economic evaluation of preventive oral health programs revealed the lacunae in the research literature on this topic. Therefore, preventive oral health programs should be economically evaluated to eliminate the disparity in resource allocation particularly in upper middle income and low-income countries.
    Keywords:  Bibliometrics; Citation analysis; Cost-effectiveness; Economic evaluation; Preventive healthcare
    DOI:  https://doi.org/10.1016/j.jobcr.2024.10.012
  10. J Relig Health. 2024 Nov 18.
    Spiritual Leadership Research: Past, Present and Future Using Bibliometric Analysis.
    Rajni, Naval Garg, Stuti Jalan.
      Given a dearth of comprehensive assessments, this study provided a quantitative and scientific analysis of 286 articles on spiritual leadership (SL) published in Scopus-indexed journals. Citation, cluster and co-citation analysis were employed to highlight the key works, sketch the intellectual framework and identify the research gaps. The most influential documents, journals, authors/researchers, countries and universities were also determined using citation analysis. Besides author co-citation and journal co-citation, analysis were also performed to determine the intellectual structure of SL literature, followed by a thorough review of authors' keywords utilizing cluster analysis. Keyword co-occurrence cluster analysis led to the identification of five major clusters/streams: (a) spiritual leadership and well-being; (b) spiritual leadership and other types of leadership; (c) spiritual leadership and creativity; (d) spiritual leadership and employee-level outcomes; (e) spiritual leadership, sustainability and spirituality. Future research directions were suggested within each identified cluster. This study will assist regulators and academic scholars in understanding the nuts and bolts of spiritual leadership and identifying areas that require more research.
    Keywords:  Bibliometric analysis; Citation analysis; Cluster analysis; PRISMA; Spiritual leadership; Workplace spirituality
    DOI:  https://doi.org/10.1007/s10943-024-02178-2
  11. Medicine (Baltimore). 2024 Nov 15. 103(46): e40450
    Visualize the time dynamics and research trends of macrophage associated periodontitis research from 2004 to 2023: Bibliometrix analysis.
    Hu Zheng, Yuhang Cai, Keyi Liu, Junwei Xiang, Wenjia Han, Yuanyin Wang, Ran Chen.
       BACKGROUND: Macrophages play an important role in the symptoms and structural progression of periodontitis, and are receiving increasing attention. In recent years, research has shown significant progress in macrophage associated periodontitis. However, there is still lack of comprehensive and methodical bibliometric analysis in this domain. Therefore, this research aims to describe the state of the research and current research hotspots of macrophage associated periodontitis from the perspective of bibliometrics.
    METHODS: This study collected and screened a total of 1424 articles on macrophage associated periodontitis retrieved between 2004 and 2023 from Web of Science Core Collection database. Use Citespace (6.1. R6), Bibliometrix-R (4.1.3), VOSviewer (1.6.19), and Graphpad Prism8 software to analyze and plot countries/regions, institutions, journals, authors, literature, and keywords to explore the research hotspots and development trends of macrophage associated periodontitis.
    RESULT: After analysis, the amount of macrophage associated periodontitis publications has been rising consistently over time, with China having the most publications (29.32%). 3 countries accounted for 65.57% of the total publications: the United States, China, and Japan, occupying a dominant position in this research field. China publications have the fastest growth rate and played a driving role. The most productive institution is the Sichuan University in China. Journal of Periodontal Research is highly popular in the field of macrophage associated periodontitis, with the highest number of publications. Grenier, Daniel is the most prolific author. Inflammation and Bone Loss in Periodontal Disease are the most cited literature. "Biological pathogenic factors," "immune regulation," "mechanism research," "susceptibility factor research," "pathological processes and molecular correlation," "pathological characteristics," "inflammatory response" are the main keyword groups in this field.
    CONCLUSION: This study systematically analyzes and describes the development process, direction, and hotspots of macrophage associated periodontitis using bibliometric methods, providing a reference for future researchers who continue to study macrophage associated periodontitis.
    DOI:  https://doi.org/10.1097/MD.0000000000040450
  12. Autoimmun Rev. 2024 Nov 17. pii: S1568-9972(24)00187-3. [Epub ahead of print]24(1): 103696
    Global research landscape on antiphospholipid syndrome and systemic lupus erythematosus: Trends, collaborations, and future directions.
    Heng Bai, Jie Tian.
       BACKGROUND: Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are frequently studied together due to their close relationship. Despite significant research in this area, bibliometric studies addressing global research trends, key hotspots, and developmental trajectories are still lacking.
    METHODS: This study employs bibliometric analysis to examine 2233 publications on APS and SLE from 1989 to 2024, sourced from the Web of Science (WOS) database. Visualization tools, such as the bibliometrix R package, CiteSpace, and VOSviewer, were utilized.
    RESULTS: The analysis includes contributions from 9322 researchers across 2534 institutions in 91 countries, with publications spread across 585 journals. Research activity has increased substantially since 2015, reflecting the growing academic interest in the field. The United States led in publication volume, while Tel Aviv University produced the highest number of publications. Lupus had the highest number of both publications and citations. Yehuda Shoenfeld is the most prolific author, while Ronald A. Asherson is the most co-cited author. Keyword analysis revealed five major themes in APS and SLE research, covering thrombosis, cardiovascular diseases, immune response, pregnancy complications, and other connective tissue diseases. Thematic map emphasized the need for future research to focus on the immune mechanisms of antiphospholipid antibodies, thrombosis management, management of pregnancy complications, and interventions for neuropsychiatric symptoms.
    CONCLUSION: This study analyzes the literature on APS and SLE, revealing trends in the research of their immune mechanisms, thrombosis management, pregnancy complications, and neuropsychiatric symptoms, and providing strong guidance for future research directions.
    Keywords:  Antiphospholipid syndrome (APS); Bibliometric analysis; Frontier hotspots; Global research trends; Systemic lupus erythematosus (SLE)
    DOI:  https://doi.org/10.1016/j.autrev.2024.103696
  13. Front Pharmacol. 2024 ;15 1478625
    Knowledge domain and trends in treatment-resistant schizophrenia (TRS) research based on CiteSpace bibliometrics analysis.
    Haipeng Cai, Ruonan Du, Jianyi Zhang, Xin Wang, Wei Li, Kebing Yang, Zhiren Wang.
       Background: Although the number of studies on treatment-resistant schizophrenia (TRS) has been increasing, the global research hotspots and future research trends have not yet been established.
    Objective: This study identify the hotspots of TRS research and predict future research trends using a bibliometric analysis.
    Methods: The Web of Science Core Collection was searched using the keyword "TRS", econometric and co-occurrence analyses were conducted using CiteSpace and VOSviewer software, and the results were visualised. PRISMA reporting guidelines were used for this study.
    Results: In total, 912 publications were included in the analysis. The number of publications on TRS has shown an increasing trend over the past 20 years. The United States and University of London were the countries and institutions with the highest total number of publications, respectively. Schizophrenia Research was the journal with the highest number of articles. American Journal of Psychiatry was the most cited journal. Based on the results of this analysis, cognitive impairment, clozapine-resistant schizophrenia, early-onset schizophrenia, and early recognition of TRS will be hotspots for future research in this field.
    Conclusion: There has been an upward trend in the number of publications on TRS each year. However, issues such as how to use antipsychotics more efficiently to treat TRS and how to predict the emergence of TRS as early as possible are still in urgent need of research and are current challenges for clinicians. The results of this study not only predict and analyse future research hotspots but also help researchers identify appropriate research directions and partners.
    Keywords:  CiteSpace; bibliometrics analysis; clozapine; efficiency; global trends; treatment-resistant schizophrenia
    DOI:  https://doi.org/10.3389/fphar.2024.1478625
  14. Front Neurosci. 2024 ;18 1434756
    Bibliometric and visualized analysis of 2014-2024 publications on therapy for diabetic peripheral neuropathy.
    Baitian Fu, Ning Luo, Yichen Zeng, Yutian Chen, Low Je Wie, Jianqiao Fang.
       Background: This research aimed to examine the global developing patterns in the treatment of diabetic peripheral neuropathy (DPN) using a bibliometric analysis of published literature.
    Methods: We extracted publication data from papers published between 2014 and 2024 using a specific topic search in the "Web of Science Core Collection" (WoSCC) database. Various metrics, such as the number of papers, citations, authors, countries, institutions, and references, were collected for analysis. To further explore the data, CiteSpace was employed to examine co-citation patterns among authors, identify collaborative efforts between countries and institutions, and uncover emerging trends using burst keywords and reference analysis.
    Results: The study encompassed 2,488 publications that exhibited an increasing trend in annual output. Notably, the journal PAIN, the United States, the Pfizer institution, and the author Feldman, EvaL emerged as the most prolific contributors to this research domain. The term "placebo-controlled trial" was the most prominent burst keyword from 2014 to 2017, whereas "spinal cord stimulation" held this distinction in the recent 5-year span. Furthermore, the publication titled "Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis-2015" demonstrated the highest burst in terms of references.
    Conclusion: This study is the first to objectively reveal the current hotspots and trends in DPN treatment. The results indicate that drug therapy remains the primary first-line treatment for DPN and that future research on DPN treatment will likely focus on "spinal cord stimulation" and "pain management." These findings provide valuable insights into DPN treatment.
    Keywords:  CiteSpace; bibliometric analysis; diabetic peripheral neuropathy; therapy; treatment
    DOI:  https://doi.org/10.3389/fnins.2024.1434756
  15. Naunyn Schmiedebergs Arch Pharmacol. 2024 Nov 21.
    Global trends and biological activity hotspots of D-limonene in essential oils: a 30-year bibliometric study.
    Haibin Wang, Qian Lu, Xiaochen Chen, Ying Qian, Biyun Qian, Hongsheng Tan.
      This study aims to conduct a comprehensive bibliometric analysis of global research trends and hotspots related to the biological activities of D-limonene, a prominent monoterpene compound found in essential oils, that warrant attention. We performed a bibliometric analysis of 1928 publications sourced from the Web of Science core database, covering the period from 1994 to 2024. Utilizing CiteSpace and VOSviewer software, we analyzed publication trends, collaboration networks among countries, institutions, and authors, and explored the evolution of research themes and current hotspots through keyword analysis. Our findings indicate a rapid increase in research on D-limonene activities since 2017, with China and Brazil leading in publication output. Italy and the USA play central roles within the collaboration network. Notably, a core group of authors has yet to emerge in this field. The biological activities of D-limonene, particularly its antibacterial, antioxidant, anti-inflammatory, and antitumor properties, are widely studied. Recent research hotspots focus on its neuroprotective effects and its potential role in inhibiting antibiotic resistance. The study highlights the growing interest in D-limonene and suggests that its use as an adjuvant to enhance therapeutic efficacy through synergistic interactions with other drugs may represent a significant research direction for the future. This analysis provides valuable insights for researchers and practitioners in pharmacology and related fields, emphasizing the importance of D-limonene in advancing health-related applications.
    Keywords:   d-Limonene; Bibliometric analysis; Biological activities; Global trends; Research hotspots
    DOI:  https://doi.org/10.1007/s00210-024-03607-5
  16. Indian J Plast Surg. 2024 Oct;57(5): 356-363
    Focuses and Trends of Research on Platelet-Rich Fibrin: A Bibliometric and Visual Analysis.
    Ying Zhao, Chen Dong, Liumeizi Fan, Ting Lei, Xin Ge, Zhou Yu, Sheng Hu.
      Background  A rapid expansion of study on platelet-rich fibrin (PRF) has gained more attention in the subject. In this study, bibliometrics were used to assess the outputs and trends of relevant PRF studies. An in-depth analysis of the publication patterns and progress in PRF research worldwide was conducted for the purpose of filling in this research gap. Materials and Methods  The analysis included 946 papers sourced from Web of Science that included 842 original articles and 104 reviews. A number of factors including country/region, institution, journal, and author were taken into account. Research on PRF development trends was mapped using the frequency of keywords. Results  In terms of the total number of publications, China ranked first with 199 papers, whereas the United States ranked first on the H-index with 37. PRF is an active research area in stomatology and craniomaxillofacial surgery. Keywords provided by the authors were designated to three clusters: red, green, and blue. "Growth factor," "platelet-rich plasma," and "bone regeneration" were the most frequent keywords in each cluster, which reflect the current interests in corresponding fields. Bone regeneration post-dental extractions is one of the main application directions in the field of oral and maxillofacial surgery. "Membrane," "injectable PRF (I-PRF)," "case report," and "advanced PRF (A-PRF)" were relative recent keywords in all clusters, indicating that manufacturing processes and new applications are promising research hotspots in the field. Conclusion  In the future, the applications of modified PRF, such as I-PRF, are promising research hotspots. Moreover, strict randomized controlled trials on PRF deserve more attention. The results of this analysis may be helpful for all scholars seeking to expand researches and innovations in the field of PRF.
    Keywords:  bibliometric analysis; bone regeneration; growth factor; injectable; membrane; platelet-rich fibrin
    DOI:  https://doi.org/10.1055/s-0044-1779478
  17. J Multidiscip Healthc. 2024 ;17 5117-5137
    Research Hotspots and Trends in Global Cancer immunometabolism:A Bibliometric Analysis from 2000 to 2023.
    Shupeng Chen, Jie Liu, Guilian He, Nana Tang, Yingjian Zeng.
       Background: Cancer poses a major global health challenge, and immunotherapy, known as the third revolution in cancer treatment, has brought new hope to patients. The emerging field of immunometabolism has further enhanced the safety and efficacy of immunotherapy. Over the past two decades, this field has rapidly evolved in oncology, leading to numerous significant findings. This review systematically examines the literature on immunometabolism in cancer, visualizing research trends and identifying future directions.
    Methods: A comprehensive literature search was conducted in the Web of Science, PubMed, and Scopus databases, covering publications from January 2000 to December 2023. We employed tools like Citespace, VOSviewer, and RStudio for visual analysis of publication trends, regional contributions, institutions, authors, journals, and keywords.
    Results: A total of 3320 articles were published by 8090 authors across 1738 institutions, involving 71 countries. Leading contributors were China (n=469), the United States (n=361), and Germany (n=82). Harvard University was the most influential institution, while Frontiers in Immunology had the highest number of publications. The top research areas included glucose, lipid, and amino acid metabolism, the tumor microenvironment, and immune cell regulation.
    Conclusion: International collaboration and interdisciplinary efforts are advancing the field of cancer immunometabolism. Future research will likely focus on the interplay between metabolism and immunity, metabolic markers, immune cell reprogramming, and tumor-immune metabolic competition.
    Keywords:  bibliometrics; immune evasion; immunity; metabolic reprogramming; metabolism; tumor
    DOI:  https://doi.org/10.2147/JMDH.S495330
  18. Int J Clin Pharmacol Ther. 2024 Nov 20.
    Immune checkpoint inhibitors: A bibliometric analysis of research trends and hotspots based on the most frequently cited clinical trials (2013 - 2021).
    Peixiang Wang, Liping Zhao, Lihua Jia, Li Wang.
       OBJECTIVE: To quantitatively and qualitatively evaluate research trends and hotspots for immune checkpoint inhibitors (ICIs), according to the most frequently cited clinical trials.
    BACKGROUND: Numerous clinical trials have been carried out using ICIs for activating anti-tumor immunity in cancer patients. The most frequently cited clinical trials have been used as a database for achieving the objectives of this analysis.
    MATERIALS AND METHODS: The most frequently cited articles on ICIs meeting the inclusion criteria were extracted from the Web of Science database. Citation report information including annual outputs, most relevant journals, and country of origin together with burst references, keywords, information on co-occurrence, citation networks, and cluster topics were analyzed using standard bibliometric procedures.
    RESULTS: A total of 112 most frequently cited articles on clinical trials of ICIs were retrieved for the period 2013 to 2021 of which the journal JAMA Oncology had the highest number of citations. Most studies originated in the U.S., and therefore studies from this country had a determinant effect of the results of the investigation. Burst reference topics included studies on ipilimumab for melanoma, anti-PD-L1 antibody in advanced cancer, anti-PD-1 antibody in cancer, nivolumab combined with ipilimumab or as monotherapy in untreated melanoma, and pembrolizumab for PD-L1 positive non-small-cell lung cancer. Nine clusters were grouped in the citation network. The topic/keywords "cancer", "immunotherapy", "PD-1 blockade", "PD-L1", "expression", "ipilimumab", "nivolumab", "pembrolizumab", and "safety" were the search priorities, whereas "multicenter", "resistance", "adverse events", and "renal-cell carcinoma" were seen as emerging topics in this specific field.
    CONCLUSION: The bibliometric analysis of the most frequently cited clinical trials with ICIs provided information on the characteristics of the studies evaluated as well as hotpots and trends in evolving immunopharmacotherapy research on ICIs.
    DOI:  https://doi.org/10.5414/CP204629
  19. Autoimmun Rev. 2024 Nov 18. pii: S1568-9972(24)00188-5. [Epub ahead of print] 103697
    Advancing understanding of autoimmune disease-related interstitial lung disease (AD-ILD): A global perspective on research focus and future directions.
    Ying-Xian Dong, Si-Cheng Zhou, Jie Tian.
       BACKGROUND: Interstitial lung disease (ILD), also known as autoimmune disease-associated ILD (AD-ILD), is a common complication of autoimmune diseases. Its rapid progression and worsening pulmonary fibrosis significantly increase the risk of mortality, leading to poor prognosis. Despite the considerable body of research in this field, there is a lack of bibliometric studies to address global research trends, key hotspots, and future directions.
    METHODS: This study employed bibliometric methods to analyze 6456 publications related to this field from 1980 to 2024, using data extracted from the Web of Science (WOS) database. Visualization was conducted using tools such as VOSviewer, CiteSpace, and the bibliometrix R package.
    RESULTS: The analysis encompassed contributions from 102 countries, 5957 institutions, and 25,003 researchers, published across 951 journals. Research output has surged since 2018, highlighting increased scholarly attention to the field. The United States produced the largest number of publications, with Mayo Clinic identified as the most prolific institution. The analysis revealed that Rheumatology and Annals of the Rheumatic Diseases had the highest publication volume and co-citation counts in the field, respectively. Dinesh Khanna was identified as the most prolific author, while V.D. Steen emerged as the most highly co-cited author. Keyword analysis highlighted that current AD-ILD research primarily focuses on optimizing diagnostic tools for specific autoimmune diseases, analyzing pathological types and risk factors, and exploring biomarkers and precision therapies. Thematic mapping underscored the need for future research to focus on AD-ILD mechanisms, specific antibodies, diagnostic markers, personalized treatments, and prognostic factors.
    CONCLUSION: This study provides a comprehensive bibliometric analysis of AD-ILD-related publications, uncovering global research trends and current hotspots while offering robust guidance for future research directions.
    Keywords:  Autoimmune disease-associated interstitial lung disease (AD-ILD); Bibliometric analysis; Frontier hotspots; Global research trends; Interstitial lung disease (ILD)
    DOI:  https://doi.org/10.1016/j.autrev.2024.103697
  20. Front Cell Neurosci. 2024 ;18 1495542
    Panaroma of microglia in traumatic brain injury: a bibliometric analysis and visualization study during 2000-2023.
    Yuhang Zhang, Tingzhen Deng, Xiao Ding, Xingyuan Ma, Yatao Wang, Haijun Yang, Ruiwen Ding, Dawen Wang, Haotian Li, Maohua Zheng.
       Background: Traumatic brain injury (TBI) is a critical global health concern characterized by elevated rates of both morbidity and mortality. The pathological and physiological changes after TBI are closely related to microglia. Microglia, the primary immune cells in the brain, are closely linked to the mechanisms and treatment of TBI. With increasing research in this area, this study employs bibliometric analysis to identify current research hotspots and predict future trends.
    Objective: We decided to perform a bibliometric analysis to provide a comprehensive overview of the advancements in microglia research related to traumatic brain injury. We aim to offer researchers insights into current trends and future research directions.
    Method: We collected all articles and reviews related to microglia and traumatic brain injury published between 2000 and 2023 from the Web of Science Core Collection. These records were analyzed using VOSviewer, CiteSpace, and the R package "bibliometrix".
    Results: We retrieved 665 publications from 25 countries, with the majority contributed by the United States and China. The number of publications on traumatic brain injury and microglia has been steadily increasing each year. Our analysis highlighted the Journal of Neurotrauma and the Journal of Neuroinflammation as the most influential journals in this field. Alan I. Faden and David J. Loane are recognized as leading contributors. Keyword analysis indicates that neuroinflammation, microglial polarization, and neurodegenerative diseases are pivotal areas for future research.
    Conclusion: In recent years, research on TBI-related microglia has proliferated, with current studies primarily focusing on microglial involvement in neuroinflammation, neurodegenerative changes, and microglial polarization following TBI. Since neuroinflammation and neurodegeneration are two hallmark features of TBI, targeting microglia in TBI treatment may become a central focus for future research.
    Keywords:  CiteSpace; TBI; VOSviewer; bibliometric analysis; microglia; traumatic brain injury
    DOI:  https://doi.org/10.3389/fncel.2024.1495542
  21. Medicine (Baltimore). 2024 Nov 15. 103(46): e40537
    Research frontiers and hotspots of coronary chronic total occlusion: A bibliometric analysis.
    Shudi Li, Menghe Zhang, Wenwen Li, Zhenhai Sun, Yunxiao Zhang, Yaoyao Zuo, Shouqiang Chen.
      By analyzing the relevant literature, we can accurately grasp the current status of diagnosis and treatment of chronic total occlusion of coronary artery, and clarify the development trend, research frontiers and hotspots of this disease. A literature search with "chronic total occlusion" as the title was performed in the Web of Science database. The title, author, abstract, keywords, institution, publication, country, reference, and other endnotes of the selected literature were exported in the form of text. The author, country, institution, and keywords of the literature were analyzed through Citespace and VOSviewer. The United States has the highest proportion of articles. The institution with the largest number of publications in this field is the Minneapolis Heart Institute Foundation. Brilakis Emmanouil S is the author with the most published articles. The journal system with the largest number of articles in this field is Cardiac Cardiovascular Systems. The keywords with the highest frequency are "chronic total occlusion," "percutaneous coronary intervention," "recanalization," and "revascularization." The burst detection analysis of hot keywords shows that "algorithm," "management," and "mortality" are the research hotspots in this field in recent years. At present, the research on this disease mainly focuses on the opening of occluded coronary arteries through various treatment methods. In the near future and the next few years, the research hotspots may be the scoring system algorithms for the treatment of chronic total occlusion of coronary artery and the management strategies for patients.
    DOI:  https://doi.org/10.1097/MD.0000000000040537
  22. Ren Fail. 2024 Dec;46(2): 2423846
    Global trends and prospects related to macrophage in chronic kidney disease: a bibliometric analysis.
    Yuxin Hu, Yaoxian Wang, Hanzhang Hong, Yexin Chen, Qinjie Zhou, Gegongming Zhu, Jingyi Tang, Weijing Liu, Lin Wang.
       BACKGROUND AND AIMS: Macrophages play a variety of widely concerned roles in the process of chronic kidney disease (CKD). To further understand the research hotspots and development trends regarding the relationship between macrophages and CKD, the role of macrophages in the occurrence and progression of CKD was summarized by bibliometrics in this study.
    MATERIAL AND METHODS: We collected the studies relevant the role of macrophages in CKD from the Web of Science Core Collection, which included 1332 relevant studies from Jan 1st, 2004 to Jul 6th, 2023 in WoSCC. CiteSpace, biblioshiny in R, VOSviewer and SCImago Graphica Beta were used for bibliometric analysis and visualization.
    RESULTS: Monash University from Australia is the most productive institution, while China and the USA are most productive countries. Anders HJ is the most cited author. In terms of the number of co-citations, the top one was "Macrophages: versatile players in renal inflammation and fibrosis" by Patrick Ming-Kuen Tang, published in Nature Reviews Nephrology in 2019. Important keywords of this research topic include inflammation, dendritic cell, oxidative stress, NF-κB, tgf-beta, interstitial fibrosis, glomerulonephritis, diabetic nephropathy. Future research hotspots may include molecular mechanism, acute kidney injury, macrophage polarization, kidney fibrosis.
    CONCLUSION: This study provides a systematic review of the role of macrophages in CKD and speculates that future research hotspots. Previous studies have focused on the immune function of macrophages and atypia, and metabolic factors (especially iron metabolism within macrophages) have attracted the attention of researchers in recent years and are the forefront of recent research.
    Keywords:  Chronic kidney disease; bibliometric analysis; diabetic nephropathy; fibrosis; macrophage; metabolic syndrome
    DOI:  https://doi.org/10.1080/0886022X.2024.2423846
  23. Medicine (Baltimore). 2024 Nov 15. 103(46): e40530
    Platelet-rich plasma: A bibliometric and visual analysis from 2000 to 2022.
    Kai Du, Ao Li, Chen-Yu Zhang, Ren Guo, Shu-Ming Li.
       BACKGROUND: Platelet-rich plasma (PRP) is an integral biotherapeutic modality with evolving significance in the medical domain. Despite its expanding applications, a comprehensive bibliometric evaluation is essential to understand its development and impact.
    METHODS: The Web of Science core collection subject search identified articles pertinent to PRP applications. Analytical tools, including CiteSpace, VOSviewer, Bibliometrix (R-Tool for R-Studio), TBtools, SCImago Graphica, Origin, and Excel, facilitated the bibliometric scrutiny. This examination spanned dimensions ranging from geographical and institutional contributions to thematic shifts and keyword prevalence.
    RESULTS: A corpus of 5167 publications was analyzed, with the United States, particularly the Hospital for Special Surgery, emerging as major contributors. The American Journal of Sports Medicine was identified as the primary journal, and Anitua Eduardo as the leading author in the domain. Keyword analysis highlighted evolving research themes, with a shift from traditional applications in orthopedics and dentistry to emerging areas such as dermatology, aesthetics, and chronic pain management.
    CONCLUSION: The bibliometric analysis of PRP research reveals a multifaceted array of applications across various medical disciplines and highlights areas requiring further exploration, particularly in standardization, personalization, and safety. Future advancements in PRP research will necessitate innovative exploration, ethical considerations, and rigorous scientific validation to fully harness the therapeutic potential of PRP and related therapies.
    DOI:  https://doi.org/10.1097/MD.0000000000040530
  24. J Multidiscip Healthc. 2024 ;17 5259-5275
    Worldwide Research Trends and Regional Differences in the Development of Precision Medicine Under Data-Driven Approach: A Bibliometric Analysis.
    Heyuan Niu, Kai Yu Li, Tao Yu, Maorun Zhang, Zhe Ji, Ping Yu, Xianfu Yi, Gang Liu.
       Background: Precision medicine is an innovative approach that integrates genomics, clinical informatics, and proteomics to address both genetic and environmental factors in disease prevention and treatment. This bibliometric study analyzes research trends, collaboration patterns, and the unique characteristics of precision medicine across countries to inform future research directions.
    Methods: A comprehensive search was conducted in the Web of Science Core Collection (1999-2022) database to identify publications related to precision medicine. The analysis of publication patterns, collaborations, institutions, authors, and research hotspots was performed utilizing Microsoft PowerPoint 2019 in conjunction with the Bibliometrix package in R.
    Results: A total of 30,777 publications on precision medicine were identified. The United States and the United Kingdom were recognized as the primary contributors, while European countries exhibited substantial collaborative efforts. Harvard University and the University of California System have played pivotal roles in advancing the field. The keywords analysis showed that in the early 2000s, "gene expression" and "personalized outcomes" were key themes. Since 2015, there's been a significant shift towards advanced technologies like artificial intelligence, machine learning, liquid biopsy, highlighting their growing importance in precision medicine. Research topics across various countries exhibit certain global similarities. However, different nations exhibit distinct thematic research focuses. China emphasizes "Informatics", "Hepatocellular Carcinoma", "Photothermal Therapy", and "Lung Adenocarcinoma", while the United States prioritizes "Informatics", "Treatment Rules", and "Consortium Guidelines". Germany and France share similar interests in particular research domains.
    Conclusion: Precision medicine is rapidly globalizing, with significant contributions from multiple countries and emerging technologies acting as catalysts for further development. Greater international cooperation is essential to elevate the quality and impact of research. These advancements hold great potential for transforming personalized healthcare by integrating cutting-edge scientific disciplines.
    Keywords:  bibliometric analysis; international collaboration; precision medicine; research topic
    DOI:  https://doi.org/10.2147/JMDH.S482543
  25. Eur J Dent. 2024 Nov 21.
    Scientific Research Trend on Guided Tissue Regeneration: A Bibliometric Analysis.
    Abdul Kareem Abdullah Alhumaidan, Beenish Fatima Alam, Asim Alsuwaiyan, Eman Ahmed Aljoghaiman, Mohammad Helmi, Saqib Ali.
       OBJECTIVES:  Guided tissue regeneration (GTR) is a widely used technique in contemporary dentistry which helps achieve regeneration of periodontal tissues. This study aims to identify leading countries, authors, institutes, journals, scientific publications, and mostly used keyword regarding role of GTR in treatment for periodontal disease using the Scopus database.
    MATERIALS AND METHODS:  A well-curated search through Scopus database for significant literature related to GTR published between 1987 and 2023 was performed. Bibliographical data which comprised of abstracts, title, keywords, references, citations, and other relevant information were composed. The data was analyzed using MS Excel and VOSviewer.
    RESULTS:  Scientific literature on GTR was manually scrutinized, and 308 paper were analyzed using the Scopus database. The first paper on GTR was published in 1987. Journal of Periodontology was identified as the leading journal, while the United States and Italy were the top contributing countries. University of Sienna was the most productive organization. Roberto Pontoriero was identified as the highly cited author. A highly cited scientific paper was published by Pintippa Bunyaratavej in 2001.
    CONCLUSION:  The present bibliometric study gives useful information related to the total number of scientific articles published from 1987 to 2023. A rising trend of scientific publication was identified which continued followed by a notable decline after 2004. The analysis also recognized the United States and University of Sienna, from Italy as most active country and organizations, while the Journal of Periodontology as the leading journal.
    CLINICAL RELEVANCE:  This study may assist in continuing education and evidence-based practice for clinicians and new researchers by providing knowledge and aiding literature searches in the domain of GTR used in treatment for periodontal conditions.
    DOI:  https://doi.org/10.1055/s-0044-1791529
  26. J Multidiscip Healthc. 2024 ;17 5277-5297
    Research-Oriented Hospitals in China: A Bibliometric and Visualization Analysis Based CiteSpace.
    Yi Hu, Zhenyu Wang, Liqun Wu.
      Research-oriented hospitals represent the primary direction for the future development of large-scale, high-level hospitals in China. Research-oriented hospitals, increasingly highlighted in domestic policies, lacks a comprehensive analysis of existing research outcomes. Bibliometric evaluates scientific research endeavors and trends in disciplines by statistically analyzing literature data. Citespace is a widely used bibliometric software that helps researchers visualize research hotspots and trends in a specific field by measuring and modeling literature data from that area. This study employs CiteSpace software to conduct a bibliometric analysis and visualization analysis of the literature in the field of research-oriented hospitals, spanning publications from 2003 to 2023 and sourced from databases including the China National Knowledge Infrastructure (CNKI), Wanfang, and Weipu (VIP). Findings indicate rapid publication growth from 2010 to 2016, followed by fluctuations characterized by alternating declines and increases. In terms of the distribution of authors and institutions, the study observes a relatively modest level of collaboration among highly productive researchers and research institutions, suggesting room for enhanced interdisciplinary and institutional partnerships. Moreover, research hotspots in the field of research-oriented hospitals can be categorized into hospital development strategy, hospital management, and technological innovation. Considering the limitations of current research and the evolution of social needs, this study suggests that future research should focus more on clarifying the essence of research-oriented hospitals, developing targeted development strategies, and addressing the numerous obstacles faced during the hospital innovation process. In conclusion, this bibliometric analysis provides a snapshot of the current research status and trend. The insights gained from this research not only aim to inform future studies but also to inspire relevant stakeholders such as policy makers, hospital managers, and scholars to strengthen practical actions, enhance the construction and operation of research-oriented hospitals, thereby improving healthcare outcomes for populations.
    Keywords:  CiteSpace; bibliometric analysis; research-oriented hospital
    DOI:  https://doi.org/10.2147/JMDH.S494939
  27. Medicine (Baltimore). 2024 Nov 15. 103(46): e40525
    Research hotspots and trends related to pain in gouty arthritis from 2014 to 2024: A bibliometric analysis.
    Chengyin Lu, Yuxing Guo, Zhiqiang Luo, Xiaomei Hu, Hui Xiong, Yang Xiang, Yang Shu, Gonghui Jian.
       BACKGROUND: Gouty arthritis is a metabolic condition caused by disordered purine metabolism and elevated uric acid levels. This study adopts a bibliometric approach to analyze current research on pain in gouty arthritis and forecast future research trends.
    METHODS: Retrieve relevant research on gouty arthritis pain in the Web of Science core collection database, screen literature, and use visualization software such as CiteSpace, Vosviewers, and R package "Bibliometrix" for analysis.
    RESULTS: The total number of documents included was 1133, with 909 articles and 224 reviews. Between 2014 and 2024, there was an overall upward trend in the number of publications about pain in gouty arthritis, with the United States of America and China ranking first and second, respectively, in terms of publication volume. The UNIVERSITY OF ALABAMA BIRMINGHAM had the most publications, and Professor DALBETH N played a key role in this field. According to the keyword analysis, disease management and treatment, particularly methods for enhancing patients' quality of life and reducing symptoms, are research hotspots. For a deeper understanding, attention is also being paid to the epidemiology and pathological mechanisms of the disease. Emerging keywords such as "gut microbiota" and "urate-lowering therapies" indicate growing interest in the interrelationship between gut microbiota and gout, and the development of new treatment methods.
    CONCLUSION: This bibliometric study reveals that research on gouty arthritis pain is actively developing. Current hot topics reflect investigations into the deeper pathological mechanisms of gouty arthritis and the development of new treatment methods, including urate-lowering therapies. There is also increasing attention on the role of gut microbiota in the disease. Despite limitations such as the preliminary nature of research methods and insufficient interdisciplinary collaboration, future research directions aim to improve the rigor of research design, strengthen international cooperation, promote unified treatment guidelines, and optimize the diagnosis and treatment of gouty arthritis with new technologies like artificial intelligence, precision medicine, and nanomedicine. This will drive the field towards a deeper scientific understanding, more effective treatment methods, and more comprehensive disease management, ultimately improving patients' prognosis and quality of life.
    DOI:  https://doi.org/10.1097/MD.0000000000040525
  28. World J Psychiatry. 2024 Nov 19. 14(11): 1755-1765
    Near-infrared spectroscopy in schizophrenia: A bibliometric perspective.
    Xin-Xing Fei, Shi-Qi Wang, Ji-Yang Li, Zhang-Yu Xu, Jian-Xiong Wang, Ya-Qian Gao, Yue Hu.
       BACKGROUND: Compared with current methods used to assess schizophrenia, near-infrared spectroscopy (NIRS) has the advantages of providing noninvasive and real-time monitoring of functional activities of the brain and providing direct and objective assessment information.
    AIM: To explore the research field of NIRS in schizophrenia from the perspective of bibliometrics.
    METHODS: The Web of Science Core Collection was used as the search tool, and the last search date was April 21, 2024. Bibliometric indicators, such as the numbers of publications and citations, were recorded. Bibliometrix and VOS viewer were used for visualization analysis.
    RESULTS: A total of 355 articles from 105 journals were included in the analysis. The overall trend of the number of research publications increased. Schizophrenia Research was identified as an influential journal in the field. Kasai K was one of the most influential and productive authors in this area of research. The University of Tokyo and Japan had the highest scientific output for an institution and a country, respectively. The top ten keywords were "schizophrenia", "activation", "near-infrared spectroscopy", "verbal fluency task", "cortex", "brain, performance", "working-memory", "brain activation", and "prefrontal cortex".
    CONCLUSION: Our study reveals the evolution of knowledge and emerging trends in the field of NIRS in schizophrenia. the research focus is shifting from underlying disease characteristics to more in-depth studies of brain function and physiological mechanisms.
    Keywords:  Bibliometrics; Bibliometrix; Near-infrared spectroscopy; Schizophrenia; VOS viewer
    DOI:  https://doi.org/10.5498/wjp.v14.i11.1755
  29. Front Neurosci. 2024 ;18 1479793
    Objective assessment of cognitive fatigue: a bibliometric analysis.
    Jia-Cheng Han, Ke Bai, Chi Zhang, Na Liu, Guan Yang, Yu-Xuan Shang, Jia-Jie Song, Dan Su, Yan Hao, Xiu-Long Feng, Si-Rui Li, Wen Wang.
       Aim: The objective of this study was to gain insight into the nature of cognitive fatigue and to identify future trends of objective assessment techniques in this field.
    Methods: One thousand and eighty-five articles were retrieved from the Web of Science Core Collection database. R version 4.3.1, VOSviewer 1.6.20, CiteSpace 6.2.R4, and Microsoft Excel 2019 were used to perform the analysis.
    Results: A total of 704 institutes from 56 countries participated in the relevant research, while the People's Republic of China contributed 126 articles and was the leading country. The most productive institute was the University of Gothenburg. Johansson Birgitta from the University of Gothenburg has posted the most articles (n = 13). The PLOS ONE published most papers (n = 38). The Neurosciences covered the most citations (n = 1,094). A total of 3,116 keywords were extracted and those with high frequency were mental fatigue, performance, quality-of-life, etc. Keywords mapping analysis indicated that cognitive fatigue caused by continuous work and traumatic brain injury, as well as its rehabilitation, have become the current research trend. The most co-cited literature was published in Sports Medicine. The strongest citation burst was related to electroencephalogram (EEG) event-related potential and spectral power analysis.
    Conclusion: Publication information of related literature on the objective assessment of cognitive fatigue from 2007 to 2024 was summarized, including country and institute of origin, authors, and published journal, offering the current hotspots and novel directions in this field.
    Keywords:  assessment; bibliometric analysis; citation analysis; cognitive fatigue; detection; mental fatigue
    DOI:  https://doi.org/10.3389/fnins.2024.1479793
  30. Heliyon. 2024 Nov 15. 10(21): e40090
    Bibliometric analysis of scholarly publications related to family medicine in Thailand.
    Nutchar Wiwatkunupakarn, Sasiwimon Moonkayaow, Abigail Morse, Nida Buawangpong, Suphawita Pliannuom, Soe Sandi Tint, Apichai Wattanapisit, Chaisiri Angkurawaranon.
       Background: Family medicine has been recognized as a medical specialty in Thailand. However, there is a lack of information about scholarly publications. Bibliometric analysis is a valuable methodology for identifying research trends and knowledge gaps in this field. This study aims to analyze scholarly publications related to family medicine in Thailand.
    Method: This bibliometric analysis was conducted based on the PubMed search in March 2023. All relevant literature related to 'family medicine' and 'Thailand' was retrieved. Performance analysis examined the publication trends from 1963 to 2023, the top 10 journals publishing relevant articles, and the number of publications by research areas. Science mapping depicted clusters of co-occurring author keywords, their relationships, and the research themes' trend over two decades.
    Results: A total of 1483 publications were retrieved. The number of publications showed an upward trend, increasing from 61 before 2000 to 359 in 2020. The Journal of the Medical Association of Thailand was the leading journal, publishing 267 articles (18.0 %). Research areas were categorized into Basic Knowledge (n = 211), Clinical Problem Solving (n = 714), Health Service (n = 256), Health System (n = 254), and Medical Education (n = 48). Science mapping identified six clusters based on 106 co-occurrence keywords, including public health, health services, medical issues in older adults, healthcare access, epidemiology, and others. Research themes have shifted from infectious diseases and public health to primary care and non-communicable diseases.
    Conclusion: Future research should focus more on implementation at a population level and healthcare system, with more investigation into geriatric care and child and maternal health.
    Keywords:  Bibliometric analysis; Family medicine; Primary care; Thailand
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e40090
  31. J Alzheimers Dis. 2024 Nov;102(2): 257-274
    Frontiers and hotspots evolution between air pollution and Alzheimer's disease: A bibliometric analysis from 2013 to 2023.
    Zhirong Liu, BingShuang Hu, Ju Tang, XinLian Liu, BaoJing Cheng, Cui Jia, LuShun Zhang.
      In recent years, the study of air pollution has received increasing attention from researchers, but a summary of Alzheimer's disease (AD) and air pollution is missed. Through combing the documents in the core dataset of Web of Science, this study analyzes current research based on specific keywords. CiteSpace and VOSviewer perform statistical analysis of measurement metrics to visualize a network of relevant content elements. The research devotes discussion to the relationship between air pollution and AD. Keyword hotspots include AD, children, oxidative stress, and system inflammation. Overall, 304 documents on air pollution and AD from 2013 to 2023 were retrieved from Web of Science. One hundred twenty-two journals published relevant articles, and the number of articles has increased gradually since the past decade. Research and development in AD and air pollution are progressing rapidly, but there is still a need for more connections with multidisciplinary technologies to explore cutting-edge hotspots.
    Keywords:  Alzheimer's disease; air pollution; bibliometric; ozone; particulate matter
    DOI:  https://doi.org/10.1177/13872877241289381
  32. Front Res Metr Anal. 2024 ;9 1466811
    Impact of scientific production of Italian scientists in exercises and sport sciences by measuring the author-weighted h-index.
    Gaetano Raiola, Giovanni Esposito, Rosario Ceruso, Francesca D'Elia, Tiziana D'Isanto.
      This study aimed to measure the consistency of the impact of scientific production, weighted by authorship, of Italian scientists in two academic disciplines (AD) of Exercise and Sports Sciences (ESS) from 2017 to 2022, with a specific focus on the subfield "Sport Sciences", using topic-specific keywords. Through the Scopus database, the scientific products of Italian ESS scientists associated with each keyword were identified. Subsequently, total and relative metric parameters from 2017 to 2022 were collected, including the total and relative number of citations. To evaluate the impact of the publications, the total and relative h-index were calculated, and weighted by considering different categories of authorship. Specific weights were attributed to each category: single author, first author, last author and co-author, following the classifications already in use on Scopus for each author. The trends of total and relative metrics, including citations and h-index, from 2017 to 2022 were analyzed using Spearman's correlation. Non-parametric linear regression analysis was used for the predictive analysis of these trends. Among the 83 identified ESS scientists, a detailed analysis revealed that 31.3% were full professors, 42.1% associate professors, and 26.6% researchers. Less than half of these scientists were directly affiliated with ESS. Despite minority representation, significant positive correlations emerge between total and relative citations from 2017 to 2022 (r = 0.687) and between the weighted total h-index and the weighted relative h-index (r = 0.965). Significant trends emerge in the metric parameters of the same scientists when analyzed separately by AD. The regression results indicate that variations in total citations and the weighted total and relative h-index can predict or explain the observed changes in 2017-2022 (p < 0.05). This result suggests that the production and impact of research in the field of ESS follow the same general trend as production and impact in the specific subfield.
    Keywords:  Scopus; citations; scientific disciplinary sectors; scientific production; sport sciences
    DOI:  https://doi.org/10.3389/frma.2024.1466811
  33. Dent Traumatol. 2024 Nov 21.
    Global Trends and Perspectives on Dental Fragment Reattachment (1988-2024): A Bibliometric and Altmetric Review.
    Julia Mulinari, Isadora Durante de Souza, Nicolle Silveira Pinho, Lucas Menezes Dos Anjos, Carla Miranda Santana, Mariane Cardoso, Aurélio de Oliveira Rocha.
      Fragment reattachment in traumatic injuries is notable for its excellent esthetic, morphological, and functional results. The aim of this study was to investigate the scientific history and trends in publications on dental fragment reattachment through a bibliometric and altmetric analysis. The search was conducted in October 2024 using Web of Science. Two researchers selected articles and extracted key study characteristics. Collaborative networks were generated using VOSviewer software. Dimensions was consulted to measure altmetric data. The Spearman correlation was used. A total of 129 articles were included. The most cited article received 160 citations. Studies were published between 1988 and 2024. The leading journal was Dental Traumatology (n = 55). Case reports (n = 63) were the most frequent study design. The majority of studies aimed at clinical case follow-up (n = 71), with coronal fractures being most commonly reported (n = 96). Young patients were most affected in the selected studies (n = 49). Tewari N stood out (n = 8). The All India Institute of Medical Sciences was prominent with seven articles. Brazil was the most prevalent country (n = 29), and Asia was the most frequent continent (n = 57). Vosviewer demonstrated collaborations among authors. According to Dimensions, significant mentions were identified on Mendeley, followed by X users. This bibliometric analysis provides a comprehensive description of the technique of fragments reattachment in traumatized teeth, which has been studied for over 36 years. Studies on this technique primarily rely on case reports describing follow-up in young patients. Intervention studies and systematic reviews are recommended. Additionally, more studies in Africa, Oceania, and North America are encouraged.
    Keywords:  altmetric analysis; bibliometric analysis; dental trauma; fragment reattachment
    DOI:  https://doi.org/10.1111/edt.13017
  34. Front Oncol. 2024 ;14 1464104
    Radiomics in precision medicine for colorectal cancer: a bibliometric analysis (2013-2023).
    Hao Li, Yupei Zhuang, Weichen Yuan, Yutian Gu, Xinyan Dai, Muhan Li, Haibin Chen, Hongguang Zhou.
       Background: The incidence and mortality of colorectal cancer (CRC) have been rising steadily. Early diagnosis and precise treatment are essential for improving patient survival outcomes. Over the past decade, the integration of artificial intelligence (AI) and medical imaging technologies has positioned radiomics as a critical area of research in the diagnosis, treatment, and prognosis of CRC.
    Methods: We conducted a comprehensive review of CRC-related radiomics literature published between 1 January 2013 and 31 December 2023 using the Web of Science Core Collection database. Bibliometric tools such as Bibliometrix, VOSviewer, and CiteSpace were employed to perform an in-depth bibliometric analysis.
    Results: Our search yielded 1,226 publications, revealing a consistent annual growth in CRC radiomics research, with a significant rise after 2019. China led in publication volume (406 papers), followed by the United States (263 papers), whereas the United States dominated in citation numbers. Notable institutions included General Electric, Harvard University, University of London, Maastricht University, and the Chinese Academy of Sciences. Prominent researchers in this field are Tian J from the Chinese Academy of Sciences, with the highest publication count, and Ganeshan B from the University of London, with the most citations. Journals leading in publication and citation counts are Frontiers in Oncology and Radiology. Keyword and citation analysis identified deep learning, texture analysis, rectal cancer, image analysis, and management as prevailing research themes. Additionally, recent trends indicate the growing importance of AI and multi-omics integration, with a focus on improving precision medicine applications in CRC. Emerging keywords such as deep learning and AI have shown rapid growth in citation bursts over the past 3 years, reflecting a shift toward more advanced technological applications.
    Conclusions: Radiomics plays a crucial role in the clinical management of CRC, providing valuable insights for precision medicine. It significantly contributes to predicting molecular biomarkers, assessing tumor aggressiveness, and monitoring treatment efficacy. Future research should prioritize advancing AI algorithms, enhancing multi-omics data integration, and further expanding radiomics applications in CRC precision medicine.
    Keywords:  bibliometric analysis; colorectal cancer; imaging biomarkers; precision medicine; radiomics
    DOI:  https://doi.org/10.3389/fonc.2024.1464104
  35. PLoS One. 2024 ;19(11): e0312731
    Gender differences in representation, citations, and h-index: An empirical examination of the field of communication across the ten most productive countries.
    Manuel Goyanes, Esperanza Herrero, Luis de-Marcos.
      Women researchers have been shown to be underrepresented in science, especially among the most productive scholars. This is especially relevant in the social sciences and humanities fields, where gender parity is closer, but disparities among top scholars are still pronounced. The gender gap in the field of communication has been explored from several approaches, but studies focusing on gender differences in representation, citations, and h-index are rather scarce. Drawing upon data retrieved from SciVal, we conducted a comparative study of the top 500 and top 100 most productive scholars (N = 5000) for each of the ten most productive countries in communication research in the 2019-2022 period: the United States, the United Kingdom, China, Spain, Germany, India, Australia, Canada, Italy, and the Netherlands. The results indicate a consistent underrepresentation of women, particularly among the top 500, across countries. Despite women being cited more frequently than men in some countries over shorter time frames, a gender bias persists favoring men, particularly when considering the h-index. All in all, our study shows that, despite hints of gender equality in citation patterns, the gender gap still constitutes a structural part of the field of communication when addressing gender representation in research productivity and long-term dynamics of research impact.
    DOI:  https://doi.org/10.1371/journal.pone.0312731
  36. Int J Surg. 2024 Oct 08.
    Mapping the scientific landscape and evolution of the international journal of surgery: A scientometric analysis (2004-2024).
    Chong Li, Jing Hu, Anqi He, Chengqi He, Weihua Zhuang.
       AIM: The purpose of this study was to analyze the publication characteristics and development of the International Journal of Surgery over its 20-year history.
    METHODS: This study included articles published in IJS during the 20 years from 2004 to 2024. The data were analyzed using the Citespace, VOS viewer, and the 'Bibliometrix' package in R software. We studied the dynamics and trend patterns of IJS literature production through descriptive bibliometrics and identified the most prolific authors, publications, institutions, and countries. Bibliometric maps were utilized to visualize published articles' content and identify the most prolific research terms and topics in IJS, as well as their evolution over time.
    RESULTS: A total of 5964 publications in the IJS from 2004 to 2023 and 356 publications in 2024 were included in the analysis. The study revealed a positive trend in literature production, although the number of articles published in IJS has slightly decreased recently. The most productive country was China (n=1,211), the most productive institution was Sichuan University (n=151), and the most prolific author was Wang Yang (n=87). The top 15 most cited articles focus primarily on research reporting standard guidelines for surgical studies. Research published in IJS mainly targeted middle-aged and older adults, emphasizing postoperative complications and treatment outcomes. The future research focus in IJS might center on integrating artificial intelligence and deep learning technologies to revolutionize surgical research and practice.
    CONCLUSIONS: The International Journal of Surgery significantly contributes to advances in surgical research. IJS prioritized enhancing patient outcomes and advancing surgical techniques, focusing on middle-aged and older adults, postoperative complications, and treatment outcomes. The journal emphasized robust evidence through retrospective, controlled, and cohort surgical studies. Integrating artificial intelligence and deep learning represented a significant frontier poised to revolutionize surgical care, shaping the future landscape of research and practice.
    DOI:  https://doi.org/10.1097/JS9.0000000000002107
  37. Braz J Biol. 2024 ;pii: S1519-69842024000100705. [Epub ahead of print]84 e288214
    Natural mortality of fish: a review.
    C P Campos, D O Inomata, S O Inomata, S Bitar, C E C Freitas.
      This paper analyzed the scientific production on natural mortality (M) in fish, in order to understand the existing methods and identify the most commonly used ones. Research was carried out in the Web of Science database (WoS), using bibliometric and systematic analysis methods to evaluate scientific production using the following indicators: relevance of scientific journals, scientific recognition of papers, relevance of authors and co-occurrence of keywords. The bibliographic portfolio was composed of the hundred most cited papers of the WoS. The most relevant papers are reviews on the topic studied, which justifies the number of citations. The most cited researchers were the authors of the main estimators of M. The keywords of greatest occurrence were: natural mortality, growth and age. Of the total papers, only 19 estimated M for 28 species. Of these papers, 58% studied population dynamics and 42% made assessments of fish stocks. The most commonly used estimators were Hoenig (1983) and Pauly (1980b). Given the results obtained, it is important to develop more sophisticated methods, taking into account new approaches, such as temperature variation within this estimator, which was not observed in any of the methods.
    DOI:  https://doi.org/10.1590/1519-6984.288214
  38. Medicine (Baltimore). 2024 Nov 15. 103(46): e39945
    Current status and hotspots in breast cancer patient self-management research: A bibliometric and visual analysis via CiteSpace.
    Xinyue Chen, Yan Cao, Shan Huang, Yanyan Chen, Cui-Ping Zhang.
       BACKGROUND: Breast cancer remains a leading cause of cancer-related mortality worldwide. Patient self-management plays a pivotal role in enhancing outcomes and quality of life for individuals affected by this disease. This study employed bibliometric and visual analysis techniques utilizing CiteSpace to elucidate the current status and research hotspots in breast cancer patient self-management from January 1, 2005, to August 31, 2023.
    METHODS: A comprehensive search was conducted in the Web of Science Core Collection (WoSCC). The retrieved literature was subjected to visualization and analysis using CiteSpace, focusing on publication timeline, article count, geographical distribution, institutional affiliations, journal sources, reference co-citation networks, and keyword analysis.
    RESULTS: The analysis encompassed 1413 English-language documents. The United States emerged as the most prolific contributor, while the University of Toronto demonstrated the highest institutional output. The two-map overlay revealed prominent citation paths, indicating strong interconnections between publications in "Medicine, Medicine, Clinical" and "Health, Nursing, Medicine," as well as "Psychology, Education, Health" and "Health, Nursing, Medicine." The most frequently co-cited reference was "Self-Management: Enabling and Empowering Patients Living with Cancer as a Chronic Illness." High-frequency keywords identified included quality of life, chronic disease, self-management, patient education, randomized controlled trials, education, and intervention. These keywords formed 11 distinct clusters related to intervention content, methodologies, outcome indicators, and emerging research trends. Keyword burst analysis predicted future research hotspots focusing on patient needs, psychological distress, Internet technology, and mobile applications.
    CONCLUSIONS: Research in breast cancer self-management is experiencing significant growth. Enhanced collaboration between countries, regions, and institutions is imperative. Further investigation is warranted, particularly in the domains of "quality of life," "patient education," and "mobile health." These findings provide valuable insights to guide future research directions in this critical field.
    DOI:  https://doi.org/10.1097/MD.0000000000039945
  39. Int J Biol Macromol. 2024 Nov 16. pii: S0141-8130(24)08580-5. [Epub ahead of print]283(Pt 2): 137770
    Comments on "Extraction, purification, characteristics, bioactivities, prospects, and toxicity of Lilium spp. polysaccharides by Li et al. (2024) in Int. J. Biol. Macromol."
    Armstrong Ighodalo Omoregie, Mansur Alhassan, Tariq Ouahbi.
      Lilium spp. polysaccharides (LSPs) are gaining significant attention for their diverse health benefits, including antioxidant, antitumor, and antibacterial properties. This paper critically analyzes a recent comprehensive review by Li et al., published in International Journal of Biological Macromolecules, focusing on LSP extraction, purification, and health benefits. While the original review offers valuable insights, this critique identifies opportunities to strengthen the bibliometric analysis section. This study employs a comprehensive search strategy in Scopus using specific keywords and covering a broader time frame (1975-2023), revealing 94 research articles on LSPs. The critique proposes improvements to enhance transparency and impact, such as specifying search queries and Boolean operators used across databases, detailing selection criteria, and incorporating advanced analyses. This article discusses author keyword analysis, co-citation analysis of cited authors, and bibliographic coupling analysis of documents using VOSviewer software. The global landscape mapping of LSP relationships involving authors, countries, and keywords was determined using RStudio software. These refinements will provide a more robust foundation for understanding the LSP research landscape and future research directions while also addressing common pitfalls and suggesting improvements in bibliometric analysis for future studies.
    DOI:  https://doi.org/10.1016/j.ijbiomac.2024.137770
  40. J Health Organ Manag. 2024 Nov 21.
    Artificial intelligence and big data from digital health applications: publication trends and analysis.
    Selma Arslantaş.
       PURPOSE: The integration of big data with artificial intelligence in the field of digital health has brought a new dimension to healthcare service delivery. AI technologies that provide value by using big data obtained in the provision of health services are being added to each passing day. There are also some problems related to the use of AI technologies in health service delivery. In this respect, it is aimed to understand the use of digital health, AI and big data technologies in healthcare services and to analyze the developments and trends in the sector.
    DESIGN/METHODOLOGY/APPROACH: In this research, 191 studies published between 2016 and 2023 on digital health, AI and its sub-branches and big data were analyzed using VOSviewer and Rstudio Bibliometrix programs for bibliometric analysis. We summarized the type, year, countries, journals and categories of publications; matched the most cited publications and authors; explored scientific collaborative relationships between authors and determined the evolution of research over the years through keyword analysis and factor analysis of publications. The content of the publications is briefly summarized.
    FINDINGS: The data obtained showed that significant progress has been made in studies on the use of AI technologies and big data in the field of health, but research in the field is still ongoing and has not yet reached saturation.
    RESEARCH LIMITATIONS/IMPLICATIONS: Although the bibliometric analysis study conducted has comprehensively covered the literature, a single database has been utilized and limited to some keywords in order to reach the most appropriate publications on the subject.
    PRACTICAL IMPLICATIONS: The analysis has addressed important issues regarding the use of developing digital technologies in health services and is thought to form a basis for future researchers.
    ORIGINALITY/VALUE: In today's world, where significant developments are taking place in the field of health, it is necessary to closely follow the development of digital technologies in the health sector and analyze the current situation in order to guide both stakeholders and those who will work in this field.
    Keywords:  Artificial intelligence; Bibliometric analysis; Big data; Citations; Digital health
    DOI:  https://doi.org/10.1108/JHOM-06-2024-0241
  41. Front Pediatr. 2024 ;12 1403671
    A bibliometric study on clinical research in neonatal encephalopathy.
    Shujun Tan, Gulizuohere Alimujiang, Nuerya Rejiafu.
      This research presents a comprehensive review of studies on neonatal encephalopathy conducted between 2005 and 2024, utilizing knowledge graph analysis through CiteSpace and VOSviewer software. A search of the Web of Science core database identified 893 articles, with the United States emerging as a prominent contributor in terms of publication volume. Key co-occurrence keywords identified include "Hypoxic-ischemic encephalopathy", "Neonatal encephalopathy", and "Therapeutic hypothermia". Notable contributors, such as Seetha Shankaran and Floris Groenendaal, have significantly advanced research in this area. Leading institutions in this field include the University of Washington, while the journal Pediatrics is recognized as a leading publication in the domain of neonatal encephalopathy. These findings provide a solid foundation for guiding future research endeavors.
    Keywords:  bibliometric; neonatal; neonatal encephalopathy; research trends; visualization
    DOI:  https://doi.org/10.3389/fped.2024.1403671
  42. Front Oncol. 2024 ;14 1438091
    Thematic trends and knowledge-map of tumor-infiltrating lymphocytes in breast cancer: a scientometric analysis.
    Jinan Shi, Lei Pan, Feixia Ma, Ganlu Zhang, Yin Duan.
       Background: Tumor-infiltrating lymphocytes (TILs), essential for the anti-tumor response, are now recognized as promising and cost-effective biomarkers with both prognostic and predictive value. They are crucial in the precision treatment of breast cancer, particularly for predicting clinical outcomes and identifying candidates for immunotherapy. This study aims to encapsulate the current knowledge of TILs in breast cancer research while evaluating research trends both qualitatively and quantitatively.
    Methods: Publications on TILs in breast cancer studies from January 1, 2004, to December 31, 2023, were extracted from the Web of Science Core Collection. Co-occurrence and collaboration analyses among countries/regions, institutions, authors, and keywords were performed with Bibliometrix R packages and VOSviewer software. CiteSpace was used for reference and keyword burst detection, while high-frequency keyword layouts were generated using BICOMB. gCLUTO was employed for biclustering analysis of the binary co-keyword matrix.
    Results: A total of 2,066 articles on TILs in breast cancer were identified. Between 2004 and 2023, the USA and Milan University led productivity in terms of country/region and institution, respectively. The journals "CANCERS," "Breast Cancer Research and Treatment," and "Frontiers in Oncology" published the most articles on this topic. Loi S was the leading author, with the highest number of publications and co-citations. Co-keyword analysis revealed six research hotspots related to TILs in breast cancer. The pathological assessment of TILs using artificial intelligence (AI) remains in its early stages but is a key focus. Burst detection of keywords indicated significant activity in "immune cell infiltration", "immune checkpoint inhibitors", and "hormone receptor" over the past three years.
    Conclusion: This study reviews recent advancements and trends in TILs research in breast cancer using scientometric analysis. The findings offer valuable insights for funding decisions and developing innovative strategies in TILs research, highlighting current research frontiers and trends.
    Keywords:  Bibliometrix; breast cancer; co-word analysis; hotspot; scientometric analysis; tumor-infiltrating lymphocytes
    DOI:  https://doi.org/10.3389/fonc.2024.1438091
  43. World J Gastrointest Oncol. 2024 Nov 15. 16(11): 4489-4505
    Bibliometric analysis of olaparib and pancreatic cancer from 2009 to 2022: A global perspective.
    Xu Feng, Yi-Han Chai, Ke-Xin Jiang, Wen-Bin Jiang, Wen-Chao Chen, Yu Pan.
       BACKGROUND: Genetic screening for breast cancer gene 1 (BRCA)1/2 mutations can inform breast/ovarian/pancreatic cancer patients of suitable therapeutic interventions. Four to seven percent of pancreatic cancer patients have germline BRCA mutations. BRCA genes aid in DNA repair, especially homologous recombination, which impacts genomic stability and cancer cell growth. BRCA1 regulates the cell cycle, ubiquitination, and chromatin remodeling, whereas BRCA2 stimulates the immune response. They predict the efficacy of platinum chemotherapy or polymerase (PARP) inhibitors such as olaparib.
    AIM: To determine the trends and future directions in the use of olaparib for pancreatic cancer treatment.
    METHODS: To evaluate the trends in how olaparib works in pancreatic cancer, we performed a bibliometric analysis. One hundred and ninety-six related publications were accessed from the Web of Science Core Collection and were published between 2009 and 2022. The analytic parameters included publications, related citations, productive countries and institutes, influential authors, and keyword development.
    RESULTS: This study visualizes and discusses the current research, including the present global trends and future directions in olaparib and pancreatic cancer. Overall, this study sheds light on optimizing the use of olaparib in pancreatic cancer treatment, offering valuable guidance for researchers in this field.
    CONCLUSION: Our findings identified trends in olaparib and pancreatic cancer, with China and the USA leading and with global cooperation tightening. O'Reilly EM's team and Memorial Sloan-Kettering had the highest output. The Journal of Clinical Oncology was the most cited journal. More PARP inhibitors are emerging, and combination therapy is suggested for future therapeutic trends.
    Keywords:  Bibliometric analysis; Breast cancer susceptibility gene; Olaparib; Pancreatic cancer; Poly (adenosine diphosphate–ribose) polymerase
    DOI:  https://doi.org/10.4251/wjgo.v16.i11.4489
  44. Aquac Nutr. 2024 ;2024 5466604
    Current Status and Global Research Trend Patterns of Insect Meal in Aquaculture From Scientometric Perspective: (2013-2022).
    Raghuvaran N, Tincy Varghese, Prasanta Jana, Angela Brighty R J, Muthiah Sethupathy A, Sudarshan S, Yahya Bin Abdullah Alrashdi, Adel Ehab Ibrahim, Sami El Deeb.
      In the past decade, insect meal has gained popularity in the animal feed industry, particularly in aquafeed, due to rising costs and decreased availability of fish meal (FM) and fish oil. Initially met with skepticism, insect meal is now seen as a promising ingredient because of its high nutrient profile. Research worldwide is exploring its potential as a FM replacement. Insects are abundant, nutritious, and environmentally friendly, as they can be reared on organic waste, minimizing the need for land, water, and energy. This research aims at obtaining a comprehensive and in-depth understanding of the current status and research trend patterns in this research field. To achieve this goal, this study conducts a mini systematic review and scientometric analysis of the global research published from 2013 to 2022 on the usage of insect meal in aquaculture. In the scientometric analysis, a total of 354 papers published by 1800 authors in 124 different journals from the Web of Science (WoS) core collection were analyzed, evaluating the number of publications, most relevant authors, organizations, top cited countries, most globally cited publications, and trending research themes in this field. The result showed that the University of Turin was the leading organization in insect meal research, whereas aquaculture was the leading journal, and author Laura Gasco was the prominent researcher in this field in the studied time frame (2013-2022). Italy was the leading country in Europe, while China dominated Asia in terms of the number of publications. The annual growth rate in insect meal research was found to be positive (23.11%), with 36.95 average citations per document. This study helps practitioners and scholars understand the current state of insect meal in aquaculture and identifies research requirements that can benefit both academia and industry.
    Keywords:  aquaculture; global research; insect meal; scientometric
    DOI:  https://doi.org/10.1155/2024/5466604
  45. Medicine (Baltimore). 2024 Nov 15. 103(46): e40405
    Research focus and emerging trends of cancer-related fatigue in nursing arena: A bibliometric analysis from 2012 to 2021.
    Rong Zheng, Xi Chen, Xiuzhi Xu, Yongxia Song, Xiaodi Ju, Wenru Wang, Jingfang Hong.
       BACKGROUND: To explore distributed characteristics and identify research focus and emerging trends related to cancer-related fatigue (CRF) in the nursing field.
    METHODS: Data were collected from the Web of Science Core Collection database between January 2012 and December 2021 using an advanced search strategy. Data were extracted and analyzed using CiteSpace and Microsoft Excel.
    RESULTS: A total of 967 articles were included in this study. The number of published nursing studies on CRF has increased with slight fluctuations. Keyword co-occurrence analysis and timeline view indicated that CRF is closely related to quality of life, and there is a correlation between CRF and other symptoms. Moreover, increasing attention has been paid to CRF nursing interventions. The assessment tools and their different language versions, risk factors and reviews of CRF were the research frontiers in recent years with citation bursts.
    CONCLUSIONS: In the field of nursing, the focus of CRF research is still on risk factors, adverse outcomes and nursing management. Assessment tools will continue to be developed and additional risk factors will be studied in the future.
    DOI:  https://doi.org/10.1097/MD.0000000000040405
  46. Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6): 5154-5169
    Association of Unsafe Sexual Behavior with Head and Neck Cancer: A Bibliometric Analysis.
    Burnis Raju, Uday Venkat Mateti, Revathi Raghunath Peecee, Prakash Patil, Pukar Khanal, Deepthi Avvaru, Vijith Vittal Shetty, Raushan Kumar Chaudhary.
      Inappropriate sexual practice like oral sex has been linked with head and neck cancer (HNC). The recent data revealed that about 20% oropharyngeal caner among Indians are associated with oral sex. Thus, we aimed to comprehensively assess the trend of research in oral sex associated with HNC and to predict the research frontiers and potential hotspots in the near future. The publications related to oral sex and HNC were retrieved from Scopus database via systematic search strategy (till 15th July 2023). VOSviewer version 1.6.19 and Biblioshiny software were used to identify the trends and research hotspots. A total of 2,179 original articles has been identified of which United States had the highest number of articles (837) followed by United Kingdom (155) and India (140). The number of articles in the area of oral sex and HNC has been increased significantly over decades (highest in 2022: 169 articles) which suggests the trend of the research. Most of the studies were from the National Cancer Institute and most of the studies were published in oral oncology journal (76) along with the 3231 citations. HNC, Human papilloma virus (HPV), oropharyngeal cancer and oral cancer are the enriched keywords which suggests that the individual practicing oral sex are prone to HPV infection which results into HNC. HPV infection mediated via oral sex might be the reason behind the surge of HNC which needs to be addressed via spreading awareness, proper counseling and integrating sex education in study curriculum.
    Keywords:  Bibliometrics; Head and neck cancer; Human papillioma virus; Oral sex; VOSviewer
    DOI:  https://doi.org/10.1007/s12070-024-04917-z
  47. Ren Fail. 2024 Dec;46(2): 2429690
    Research on the global trends of COVID-19 associated acute kidney injury: an updated bibliometric analysis.
    Heng Bai, Si-Yang Liu, Jie Tian, Yu Li.
      
    DOI:  https://doi.org/10.1080/0886022X.2024.2429690
  48. Discov Oncol. 2024 Nov 19. 15(1): 679
    Targeting ferroptosis reveals a new strategy for breast cancer treatment: a bibliometric study.
    Junlin Liu, Rong Tang, Jie Zheng, Ke Luo.
       BACKGROUND: Studies exploring the role of ferroptosis in the pathogenesis of breast cancer have proliferated over the past decade, especially in 2023, with a staggering 217 publications in related studies. However, there are still significant gaps in comprehensive scientometric analysis and mapping of scientific studies, especially in terms of temporal and study area tracking, principal investigators, and the emergence of new hotspots.
    OBJECTIVE: This study aims to summarize the role of ferroptosis in the development of breast cancer and the latest research results on the ferroptosis-targeted treatment of breast cancer and to use bibliometric methods to draw a visual map to explore future research trends.
    METHODS: On May 11, 2024, this study updated the research progress related to ferroptosis and breast cancer over the past 11 years by retrieving data from January 1, 2014, to May 1, 2024, from the Web of Science database. In this research, many scientific analysis software including VOSviewer, chorddiag R Language Pack, Scimago Graphica, Citespace 6.3.R1, Cluster Profiler, enrichplot, ggplot2 R Language Pack, Cytoscape, and STRING online platform are used to make in-depth scientific analysis and visualization of the measurement results.
    RESULTS: Statistical analysis of these data showed that China accounted for 74.43% of the total publications, highlighting China's dominant role in research on the relationship between ferroptosis and breast cancer. Several research institutions, including Sun Yat-sen University, Zhejiang University, and Shanghai Jiao Tong University, have achieved impressive results. Efferth, Thomas is the most prominent author in this field and has the highest number of publications in the subfield of oncology. This study clearly shows that ferroptosis plays a crucial role in the development of triple-negative breast cancer, hepatocellular carcinoma, glioma, leukemia, mitochondrial disease, lymphoma, bladder tumors, lung adenocarcinoma, and esophageal tumors.
    CONCLUSION: This study provides a comprehensive bibliometric evaluation that deepens our understanding of the role of ferroptosis in the pathogenesis of breast cancer and the current status of targeting ferroptosis for treating breast cancer. Thus, it helps researchers in related fields explore new research directions by comprehensively extracting important information and research hotspots.
    Keywords:  Bibliometrics; Breast cancer; Citespace; Ferroptosis; Measurement analysis
    DOI:  https://doi.org/10.1007/s12672-024-01569-x
  49. Arthroplast Today. 2024 Dec;30 101564
    What Are the Research Highlights of Periprosthetic Joint Infections From the 100 Most Cited Studies?
    Marcos R Gonzalez, Jose I Acosta, Joshua Davis, Felipe Larios, Adam S Olsen, Antonia F Chen.
       Background: Periprosthetic joint infections (PJIs) are a serious complication after total joint arthroplasty. Our study aimed to analyze the characteristics and research highlights of the top 100 most cited studies on PJI from an orthopaedic standpoint. Moreover, we sought to assess whether there has been a change in the level of evidence (LOE) throughout time.
    Methods: We conducted a search of the PubMed, Embase, and Web of Science databases to identify the top 100 studies primarily focusing on PJI. Study characteristics assessed included publication year, LOE, journal of publication, and type of study. Research highlights of the included studies were classified into 6 sections. Linear regression was employed to assess correlation between LOE and publication year.
    Results: The aggregated citation count of all studies was 19,558 and the median citation number was 129.5. While cohort studies were the most prevalent, articles focusing on analysis of costs associated with PJI care or PJI definition garnered the highest yearly citation counts. The bulk of included studies were concentrated in 3 orthopaedic journals and published in the 2010s. The majority of studies had a LOE II (30%) or III (34%). On regression analysis, LOE was not correlated with publication year (Pearson's r = 0.013, P = .61).
    Conclusions: The most cited PJI articles assessed the definition of PJI and PJI cost. Despite growing interest in PJI, the majority of studies had LOE II or III, highlighting the difficulty of conducting prospective randomized controlled trials in PJI patients.
    Level of evidence: IV.
    Keywords:  Periprosthetic joint infection; Prosthetic joint infection; Total hip arthroplasty; Total knee arthroplasty
    DOI:  https://doi.org/10.1016/j.artd.2024.101564
  50. Tunis Med. 2024 Nov 05. 102(11): 858-865
    From Thesis to Publication: Unveiling the Predictive Factors for Cardiology Research at a North African Faculty of Medicine (Tunisia).
    Faten Yahia, Hamza Gazzeh, Fares Ben Mansour, Youssef Zanina, Elyes Neffati, Ahmed Ben Abdelaziz.
       INTRODUCTION: The benchmark of a medical thesis' success is often its acceptance for publication in an indexed journal.
    AIM: To determine the publication rate of practice theses in the field of Cardiology at the Faculty of Medicine of Sousse (FMSo) in Tunisia and to identify predictive factors for successful publication.
    METHODS: We conducted a descriptive bibliometric analysis of Cardiology theses defended at FMSo from 2000 to 2019. Data were extracted from the theses' cover pages, abstracts, and conclusions. The publication status was ascertained via searches in "MEDLINE", "Scopus", and "Google Scholar". Predictive factors for publication were identified using multivariate analysis with a 90% Confidence Interval (CI).
    RESULTS: Of the 111 Cardiology theses defended at FMSo between 2000 and 2019, 36 were published yielding 42 scientific articles (publication rate of 32%). Notably, 86% of these articles were indexed in "MEDLINE" and/or "Scopus". In 79% of cases, doctoral candidates were co-authors of the resultant publications. Publication was significantly influenced by three factors: scientific mentorship by an Assistant or Associate Professor (aOR=3.021; 90%CI: 1.06-10.14; p=0.082), a prospective study design (aOR=2.536; 90%CI: 1.07-6.02; p=0.076), and a satisfactory quality of writing (aOR=2.384; 90%CI: 1.11-5.11; p=0.061).
    CONCLUSION: The publication of Cardiology theses at FMSo was found to be associated with the prospective design of the study and the quality of writing. Thus, it is imperative to enhance the research methodology and scientific communication skills of medical thesis candidates and their mentors to facilitate the transition from academic dissertations to medical articles.
    Keywords:  Academic dissertation; Bibliometrics; Medical Writing; Medicine; Publications; Schools; Tunisia
    DOI:  https://doi.org/10.62438/tunismed.v102i11.5230
  51. Front Microbiol. 2024 ;15 1479941
    Debate on the relationship between Helicobacter pylori infection and inflammatory bowel disease: a bibliometric analysis.
    Ziye Wang, Shiqing Zhao, Xiaotian Zhong, Yi Su, Yahan Song, Jun Li, Yanyan Shi.
       Background: Inflammatory bowel diseases (IBD) are chronic inflammation conditions affecting the gastrointestinal tract. Studies point out an association between Helicobacter pylori (H. pylori) infection and IBD. This study aims to visually assess the research trends and hotspots in the field of H. pylori infection and IBD, review mainstream perspectives in this field, and provide a foundation for future research and treatment.
    Methods: We searched the Web of Science Core Collection Database for literature related to H. pylori and IBD, using VOS viewer to generate visual charts.
    Results: A total of 246 publications were included, with articles being the predominant type of document. A significant increase in the number of publications was observed after 2011. China contributed the most of researches. Keyword clusters revealed that the researches primarily focused on immune mechanism, gut microbiome, diagnosis and treatment of IBD. Time trend results indicated that current researches centered on gut microbiota and immune mechanisms.
    Conclusion: H. pylori infection may have a protective effect on IBD. The exact mechanisms remain unclear and may involve immunomodulation and changes of gut microbiota. Further researches are necessary for better understanding this relationship and its implications for clinical practice. Further researches and clinical practice should pay attention to this topic.
    Keywords:  Crohn’s disease; H. pylori; immune modulation; inflammatory bowel disease; intestinal microbiota; ulcerative colitis
    DOI:  https://doi.org/10.3389/fmicb.2024.1479941
  52. Cureus. 2024 Oct;16(10): e71829
    Yoga in Cancer Care: A Bibliometric Analysis of Systematic Reviews.
    Selvaraj Giridharan, Soni Soumian, Nagaraj V Kumar.
      Yoga has gained recognition as a complementary intervention for managing the physical and psychological challenges faced by patients with cancer. Systematic reviews of yoga interventions have provided valuable insights into their roles in cancer care. This bibliometric analysis aimed to map the trends, contributors, and thematic focus of systematic reviews on yoga interventions in oncology. A comprehensive search was conducted across major databases, including PubMed, Scopus, and Web of Science, to identify systematic reviews and meta-analyses focusing on yoga interventions in cancer patients. Studies published between the inception of each database and July 2024 were included. Key data, such as authorship, year of publication, cancer type, outcomes assessed, and geographical distribution, were extracted and analysed. A total of 42 systematic reviews and meta-analyses were included in the final analysis. Most studies have focused on psychological outcomes including quality of life, stress reduction, and fatigue management, with a predominant focus on breast cancer. The majority of the research was led by authors from China and the United States, reflecting a growing global interest in yoga as an integrative cancer therapy. This analysis highlights the increasing research interest in yoga for cancer care, particularly regarding psychological outcomes. Future research should focus on underrepresented cancer types and physiological outcomes, and expand studies to low- and middle-income countries to optimise yoga's role in global cancer care.
    Keywords:  bibliometric analysis; cancer care; integrative oncology; systematic reviews; yoga interventions
    DOI:  https://doi.org/10.7759/cureus.71829
  53. J Surg Res. 2024 Nov 19. pii: S0022-4804(24)00686-3. [Epub ahead of print]304 232-236
    Gender Disparity in Surgical Research: An Analysis of Authorship in Randomized Controlled Trials.
    Giulia Becherucci, Alessandro De Cassai, Giulia Capelli, Stefania Ferrari, Ilaria Govoni, Gaya Spolverato.
       INTRODUCTION: Despite increasing female representation in medical fields, women remain underrepresented in high-impact authorship positions. This study examines gender disparities in authorship of randomized controlled trials in general surgery journals over the past 20 y.
    METHODS: Utilizing PubMed and the Journal Citation Reports (Clarivate, 2023), we identified 8810 randomized controlled trials from 117 surgery journals, filtering down to 5694 studies for final analysis. Gender identification was performed using Genderize.io.
    RESULTS: Results indicate that women accounted for 26.4% of first authorships and 18.7% of last authorships. Logistic regression revealed that a male last author significantly increases the likelihood of a male first author (odds ratio 2.68; 95% confidence interval 2.18-3.32). Over time, there is a positive trend in female authorship, with high correlation coefficients for both first (Spearman's correlation coefficient 0.916, P < 0.005) and last (Spearman's correlation coefficient 0.878, P < 0.005) authors. Interestingly, journal quartiles did not significantly influence the gender of first authors.
    CONCLUSIONS: These findings suggest persistent gender inequity in surgical research authorship, influenced by mentorship dynamics. The study underscores the need for strategies to enhance female representation in academic leadership to foster a more equitable scholarly environment. Limitations include reliance on Genderize.io for gender determination and the focus on general surgery journals, which may omit relevant studies from other domains. Overall, this research highlights incremental progress toward gender equality in surgical academia, advocating for continued efforts to close the gender gap.
    Keywords:  Authorship; Gender gap; Randomized controlled trials; Scientometric
    DOI:  https://doi.org/10.1016/j.jss.2024.10.033
  54. Drug Discov Today. 2024 Nov 19. pii: S1359-6446(24)00372-6. [Epub ahead of print] 104247
    Mapping epilepsy biomarkers: a bibliometric and content analysis.
    Irma Wati Ngadimon, Mohd Farooq Shaikh, Devi Mohan, Wing Loong Cheong, Ching Soong Khoo.
      Epilepsy, a complex global neurological disorder, has spurred extensive research efforts focused on enhancing diagnostic and therapeutic strategies, with a growing emphasis on the identification of biomarkers. This bibliometric study examines 1,774 publications from 2000 to 2023, revealing a notable increase in research activity, particularly in the past decade. The US, China, and the UK lead contributions, with Asian countries exhibiting growing potential. Keyword co-occurrence analysis reveals a shift towards investigations of neuroinflammatory and genetic biomarkers, as well as emerging areas such as artificial intelligence and epigenetics. Content analysis links specific epilepsy aetiologies to biomarkers, offering promising possibilities for personalised diagnostics and treatments. These findings yield valuable insights into current trends, guiding future research and informing the development of targeted approaches for the diagnosis and treatment of epilepsy.
    Keywords:  VOSviewer; biomarker; epilepsy; predictor; scientometric; seizure
    DOI:  https://doi.org/10.1016/j.drudis.2024.104247
  55. World Neurosurg. 2024 Nov 20. pii: S1878-8750(24)01905-3. [Epub ahead of print]
    Global Trends of Mechanical Thrombectomy in Acute Ischemic Stroke Over the Past Decade: A Scientometric Analysis Based on WOSCC and GBD Database.
    Mingfen Wu, Zijun He, Kefu Yu, Luofei Zhang, Zhigang Zhao, Bin Zhu.
       OBJECTIVE: To present a global overview of the current research landscape and emerging trends in mechanical thrombectomy (MT) for acute ischemic stroke (AIS) over the past decade.
    METHODS: A thorough search was conducted on the Web of Science on May 20, 2024, focusing on original articles and reviews in English. Bibliometric tools were employed to make a network analysis and visual representation. Additionally, data on disability-adjusted life years (DALYs), prevalence, and incidence of ischemic strokes were extracted from the Global Burden of Disease database.
    RESULTS: 7776 papers were included, indicating a steady increase from 169 to 1311 between 2014 and 2023. The United States led in core publications with 2887 papers. The incidence and DALYs of ischemic stroke have continued to rise in Asia but have recently declined in North America and European countries. The University of Calgary emerged as the leading institution and Goyal M was the most prolific author. Neurointerventional Surgery was the top-contributing journal with 790 articles. The analysis identified 6,332 keywords forming 5 clusters, with 'mechanical thrombectomy' serving as the largest cluster, focusing mainly on interventional thrombectomy techniques for AIS. The term 'tissue plasminogen activator' exhibited strong burst strength of 46.58. Keywords such as 'injury', 'diagnosis', 'posterior circulation', and 'severity' burst in 2020 and lasted until 2024.
    CONCLUSION: Interest in MT for AIS was progressively increasing. Future research directions may include minimizing intraoperative injuries, refining diagnostic techniques, investigating interventions for posterior circulation, and tailoring thrombectomy strategies based on stroke severity and LVO etiology.
    Keywords:  acute ischemic stroke; arterial thrombectomy; endovascular treatment; large vessel occlusion; mechanical thrombectomy
    DOI:  https://doi.org/10.1016/j.wneu.2024.11.045
  56. Acta Psychol (Amst). 2024 Nov 21. pii: S0001-6918(24)00489-X. [Epub ahead of print]251 104611
    A vivid study on corporate social responsibility and its internal perception: Bibliometric analysis approach.
    Suong Huynh Thi Thu, Anh Le Xuan Quynh.
      Corporate Social Responsibility (CSR) is growing as a strategic tool creating a completive edge for any organizations. Together with CSR, employees are a fundamental driving force as they are responsible for achieving the business's objectives. This article primarily aims to provide directions for researchers in developing a theoretical framework and to assist new scholars exploring CSR-employee research by identifying key themes, publication trends, journals and authors relevant to this field. The authors used bibliographic coupling to scrutinize 399 articles on Scopus between 2013 and 2023. It is considered the rare study using bibliometric approach to review publications related to CSR and its internal perception review. The bibliographic coupling analysis identified five themes in CSR-employee relationship. These include CSR and Organization-related Employee Attitudes and Behaviors; CSR, Workplace Green Behavior and well-being; CSR and work perceptions; CSR and Employees' Behavioral Dynamics; CSR and Employee Volunteerism. Subsequently, this study offers insights into the most significant and current contributions to the field regarding the evolving landscape of research in the CSR-employee domain, identifying cutting-edge thematic topics in this area and enhancing understanding of its current state.
    Keywords:  Bibliographic coupling; CSR- employee; Corporate social responsibility; Employee's outcome; Internal CSR conceptualization
    DOI:  https://doi.org/10.1016/j.actpsy.2024.104611
  57. World Neurosurg. 2024 Nov 20. pii: S1878-8750(24)01919-3. [Epub ahead of print]
    Survival Analysis of Glioblastoma: A Scientometric Perspective.
    Zahra Alirezaei, Alireza Amouheidari, Reza BasirianJahromi, Shohreh Seyyedhosseini, Ali Hamidi.
      Glioblastoma is the most aggressive primary brain tumor, and the outlook for patients is usually pessimistic. Numerous ongoing studies have focused on enhancing the survival rate of glioblastoma patients. This study aims to analyze the research trends surrounding glioblastoma survival and facilitate studying recent topics to provide insight into the perspective, research fields, and international collaborations. Data were collected from the Web of Science database documents published from 1980 to 2022 and analyzed using Citespace and Biblioshiny software. After analyzing the data, we visualized the co-occurrence and co-authorship networks. . Eighteen main clusters were formed by drawing a document co-citation network. The result indicates that Prognostic biomarkers, treating field, T cell, radiomic feature, and 5-aminolevulinic acid were trending topics for researchers. The most active countries in this field are the United States, followed by China, Germany, and Italy, respectively. Considering the significance of monitoring the studies in glioblastoma patients, the current research has shown promising results in stratifying patient survival as a valuable tool for prognosis and prediction and eventually guiding treatment decisions. Using the results of this study, glioblastoma researchers can identify their potential colleagues and research gaps in this field.
    Keywords:  Biblioshiny; Citespace; Data visualization; Glioblastoma; Scientific network; Scientometric; survival
    DOI:  https://doi.org/10.1016/j.wneu.2024.11.059
  58. Indian J Psychol Med. 2024 May 29. 02537176241251616
    Delusional Procreation Syndrome: A Citation Analysis and Review from the First 12 Years of Publication.
    Anil Kumar M Nagaraj, Rashmi Vishwanath, Narayana Manjunatha.
       Background: Delusional procreation syndrome (DPS) consists of sequential delusions related to human procreation. It was first coined in a case series in 2010. The most common delusion among DPS is related to pregnancy. It will be interesting to look into its further research and impact on the scientific community.
    Aim and methodology: We performed a citation analysis using the search term "delusional procreation syndrome." For the citation, we searched Google Scholar, Web of Science, and Scopus.
    Results and conclusion: Citation analysis found that 12 other articles have cited the original publication in different contexts and were published on all continents except South America. Apart from the primary article, the subsequent citations reported the delusion of delivery, the delusions of polygamy in proxy, twin delivery, and triplet pregnancy. Thus, DPS remains an interesting and active area of research.
    Keywords:  Delusional procreation syndrome; citation analysis; delusion of pregnancy
    DOI:  https://doi.org/10.1177/02537176241251616
  59. Food Res Int. 2024 Dec;pii: S0963-9969(24)01354-1. [Epub ahead of print]197(Pt 2): 115284
    Conilon coffee: A critical review and bibliometric analysis for the agri-food industry.
    Rafael Fernandes, Fernando Oliveira Souza, Dhayna Oliveira Sobral, Taís Letícia Oliveira Dos Santos, Maria Angela A Meireles, Eduardo Augusto Caldas Batista, Alexandra Mara Goulart Nunes Mamede.
      This study includes a bibliometric analysis and literature review on Conilon coffee and its relevant aspects for the food industry, focusing on its chemical constituents, the application of fermentation as a processing method, and the reuse of waste generated during processing. Relevant articles were selected through a bibliometric analysis of titles indexed in the Web of Science (WoS) and Google Scholar databases. Conilon coffee cultivation, especially in the Brazilian states of Espírito Santo, Rondônia and Bahia, has played a growing role in the global economy, with research focused on strategies to increase productivity, reduce costs and improve nutritional and bioactive quality. The use of agricultural waste as substrates for seedlings and genetic manipulation to develop clonal cultivars are showing promise, although some options may increase the heavy metal content in plants. This review enabled the identification of the main chemical constituents of Conilon coffee and an assessment of their contributions to the product's sensory attributes and bioactive properties. It was clear that the choice of fermentation conditions changes the sensory characterization of coffee, potentially benefiting the overall rating of the beverage. This review also suggests that Conilon coffee residues contain volatile compounds of considerable commercial value, so they should be subjected to extraction methods and subsequently preserved. Acid hydrolysis and microencapsulation can be alternatives for extracting and preserving compounds of interest from Conilon coffee. This work contributes to deepening knowledge about the challenges faced by Conilon coffee and the search for alternatives to increase its market value.
    Keywords:  Chemical constituents; Coffea canephora Pierre ex A. Froehner; Fermentation; Reuse of waste
    DOI:  https://doi.org/10.1016/j.foodres.2024.115284
  60. Ther Adv Cardiovasc Dis. 2024 Jan-Dec;18:18 17539447241300022
    Diversity in the editorial boards of medical journals: a perspective from the Middle East.
    Zainab Atiyah Dakhil, Mohammed Dheyaa Marsool Marsool, Mohammed Saad Qasim, May Saad Al-Jorani.
      Despite the significant increase in women in academic medicine over the last 50 years, women are still under-represented in leadership positions in academia. However, there is a lack of data on the diversity of editorial boards in Middle Eastern medical journals. So, we aim to portray the diversity of editorial boards of Iraqi medical journals by conducting a cross-sectional analysis of the editorial boards' members of all Iraqi medical journals. Gender, affiliation and specialty were extracted from the journals' websites and/or from the professional profiles of the editorial board members. Twenty-five journals and 446 editorial board members were analysed. More than half of editorial board members specialized in basic science, while 39.76% specialized in clinical specialties. Approximately, 20.18% of editorial board members (regardless their role) were women. Four percent of editor-in-chief were women. There were significant differences in editorial role according to gender (p < 0.0001), yet residency (p = 0.688) and specialty (p = 0.190) did not differ according to their gender. Most editorial board members were affiliated with Baghdad. So, we can conclude that there is a significant under-representation of women across all roles on the editorial board of medical journals especially in the leading positions. All stakeholders, publishers, authors and academics should commit to ensure the diversity of editorial boards.
    Keywords:  academia; diversity; equity; gender; geography; inclusion; sex; women
    DOI:  https://doi.org/10.1177/17539447241300022
  61. J Hand Surg Eur Vol. 2024 Nov 22. 17531934241297508
    Authorship and publication trends in the congenital hand surgery literature.
    Ayush D Shah, Caroline H Hu, Ann E Van Heest, Deborah C Bohn.
      This study assessed authorship and publication trends in congenital upper limb difference literature. Congenital upper limb difference literature is widely distributed across multiple journals; no single journal published a clear majority. Female authorship was more likely, though reasons for this remain unclear.
    Keywords:  Authorship trends; bibliometrics; congenital hand; congenital upper limb differences; paediatric hand
    DOI:  https://doi.org/10.1177/17531934241297508
  62. Postgrad Med J. 2024 Nov 21. pii: qgae161. [Epub ahead of print]
    Bridging the gap: advancing gender equality in medical research.
    Yang Wang, Jiale Li, Xu Ou-Yang, Mingzhong Wan, Yan Wang, Guochao Zhang, Hang Yi.
       INTRODUCTION: Gender inequality in medical research persists globally, hindering scientific innovation and social equity. Despite incremental progress, women remain underrepresented in authorship, funding, and leadership roles. This review explores the extent of gender disparities, their impact, and strategies to advance equity in the field.
    METHODS: We conducted a narrative review of studies retrieved from PubMed, Web of Science, and Google Scholar, focusing on gender disparities in authorship, research funding, leadership, and editorial representation across regions and disciplines.
    RESULTS: Women are consistently underrepresented in medical research, with disparities in publication rates, grant awards, and conference participation. Key barriers include implicit biases, structural inequities, and socio-cultural norms. Promising interventions, such as targeted funding policies and mentorship programs, show potential but require broader adoption and evaluation.
    CONCLUSION: Addressing gender inequality in medical research demands comprehensive reforms in academic evaluation, funding systems, and institutional policies, alongside sustained efforts to challenge societal biases.
    Keywords:  academic publishing; career advancement; editorial representation; gender equality; research funding
    DOI:  https://doi.org/10.1093/postmj/qgae161
  63. Autoimmun Rev. 2024 Nov 17. pii: S1568-9972(24)00180-0. [Epub ahead of print]24(1): 103689
    Reply to "Refining search and keyword strategies in autoimmune ear disease bibliometric studies".
    Yu-Chen Liu, Yi-Pin Yang, Yan-Xun Han, Bing-Yu Liang, Hai-Feng Pan, Ye-Hai Liu.
      
    Keywords:  Autoimmune diseases; Bibliometric analysis; Hearing loss; Mechanisms of co-morbidity
    DOI:  https://doi.org/10.1016/j.autrev.2024.103689
  64. J Surg Educ. 2024 Nov 16. pii: S1931-7204(24)00494-X. [Epub ahead of print]82(1): 103346
    Identifying the Next Generation of Academic Surgeons and Physician Leaders.
    Nicole Russell, Jennifer L Grant.
      Many highly competitive academic general surgery residency programs share the mission of training the next generation of academic surgeons. There is a widely held belief that encouraging publications throughout residency will promote sustained research productivity and facilitate a pathway into an academic career. Consequently, the total number of publications is one of the strongest predictors for resident selection among top ranked general surgery programs. However, there is currently a lack of evidence supporting the assumptions that preresidency productivity will be sustained or predictive of an academic career. With an increasingly competitive applicant pool and recent paradigm shifts in the evaluation of applicants, it is becoming increasingly important for program directors to identify meaningful metrics to predict sustained academic success and successful academic surgeons. We discuss current trends in the evaluation of applicants' research, limitations of these methods, potential implications, and alternatives.
    Keywords:  Academic; General surgery; Medical students; Publication trends; Residents; Undergraduate medical education
    DOI:  https://doi.org/10.1016/j.jsurg.2024.103346
  65. Dev Genes Evol. 2024 Nov 16.
    Women authors in the first 50 years of DGE-contributions and research topics.
    Volker Hartenstein, Tamara Franz-Odendaal, Angelika Stollewerk.
      Wilhelm Roux promoted the newly emerged field of developmental mechanics by establishing the journal 'Archiv für Entwicklungsmechanik', currently known as 'Development, Genes and Evolution'. The founder and supporters of the journal were all men, as were the authors in the first 3 years of the journal's existence. We therefore addressed the question-in what ways did women scientists contribute to this new research field and what impact did they have. By investigating the careers and research environment of women authors in the first 50 years of the journal, we show that women contributed to all research areas of developmental mechanics and shaped its future direction.
    Keywords:  Developmental mechanics; Research environment; Scientific careers; Women researchers
    DOI:  https://doi.org/10.1007/s00427-024-00724-2
  66. PeerJ. 2024 ;12 e18442
    A review of advancements in the theory and characterization of soil macropore structure.
    Yanwen Cao, Kai Zhang, Shuyu Liu, Yilin Wang.
      Soil has an intricate pore structure, with the macropore structure serving as a pivotal component of gas exchange, liquid flow, and solute transport within the soil matrix. Scientifically understanding the macropore structure is important for the exploration of soil ecological functions. Drawing upon research literature from diverse nations, this study presents a comprehensive summary of past research findings, thoroughly examining the definition and taxonomy of soil macropores. Additionally, we delve into the factors that affect macropore structure, the effects of macropores on soil ecological functions, and the indicators that describe the nature of macropores. Furthermore, the principles, suitability conditions, benefits, and limitations of the widely utilized techniques for characterizing soil macropore structure were outlined, including staining observation, soil water retention curve, mercury intrusion porosimetry, gas adsorption, nuclear magnetic resonance, scanning electron microscopy, and computed tomography (CT). A comparative analysis was conducted to assist scholars in comprehending the theory of soil macropores, facilitating the selection of suitable macropore structure characterization techniques, and enabling the development of collaborative application modes among these techniques. Using the Web of Science core collection database, bibliometric software such as VOSviewer and CiteSpace were employed to explore the research hotspots and trends in CT, which is currently the most popular technique for characterizing soil macropore structure. This analysis offers insights into the future prospects of CT in the field of soil macropore structure characterization techniques. This article is of particular interest to readers engaged in the characterization of soil macropores.
    Keywords:  Bibliometric analysis; Computed tomography; Mercury intrusion porosimetry; Pore structure characterization; Quantification; Soil macropore
    DOI:  https://doi.org/10.7717/peerj.18442
  67. BMC Med. 2024 Nov 21. 22(1): 548
    Strategic interventions in clinical randomized trials for metabolic dysfunction-associated steatotic liver disease (MASLD) and obesity in the pediatric population: a systematic review with meta-analysis and bibliometric analysis.
    Isabel Omaña-Guzmán, Marisol Rosas-Diaz, Yoscelina Estrella Martínez-López, L Monserrat Perez-Navarro, Alvaro Diaz-Badillo, Anthony Alanis, Alejandra Bustamante, Octelina Castillo-Ruiz, Noemi Del Toro-Cisneros, Diego Armando Esquivel-Hernandez, Gloria Garcia-Villalobos, Nayely Garibay-Nieto, Esperanza Milagros Garcia-Oropesa, Juan Carlos Hernandez-Martinez, Elena Beatriz Lopez-Sosa, Carlos Maldonado, David Martinez, Joshua Membreno, Oscar Omar Moctezuma-Chavez, Claudia X Munguia-Cisneros, Edna J Nava-González, Adriana L Perales-Torres, Adolfo Pérez-García, Hector Rivera-Marrero, Alisha Valdez, Alfonso Alejandro Vázquez-Chávez, Carlos Ramirez-Pfeiffer, Kathleen V Carter, Beatriz Tapia, Leonel Vela, Juan Carlos Lopez-Alvarenga.
       BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is a prevalent hepatic condition linked to metabolic alterations. It gradually causes liver damage and potentially progresses to cirrhosis. Despite its significance, research, especially in the pediatric population, is limited, leading to contradictory findings in diagnosis and treatment. This meta-analysis aims to synthesize existing literature on therapeutic interventions for MASLD in children and adolescents.
    METHODS: A comprehensive search of randomized controlled clinical trials yielded 634 entries from PubMed, Scopus, and Web of Science up to 2023. Interventions included medications, behavioral modifications, dietary changes, probiotics, supplements, surgical procedures, or combinations. The analysis focused on studies with treatment duration of at least 3 months, employing a random-effects REML meta-analysis model. Treatment effects on anthropometric measurements and biochemical components were examined and adjusted for heterogeneity factors analysis. A bibliometric analysis for insights into research contributors was performed.
    RESULTS: The systematic review incorporated 31 clinical trials, with 24 meeting criteria for meta-analysis. These comprised 3 medication studies, 20 with supplements, 4 focusing on lifestyle, and 4 centered on diets. Significant overall treatment effects were observed for ALT, AST, BMI, and HOMA-IR mainly by supplements and lifestyle. Meta-regression identified age, BMI changes, and treatment duration as factors modifying ALT concentrations. Bibliometric analysis involving 31 linked studies highlighted contributions from 13 countries, with the USA, Spain, and Chile being the most influential.
    CONCLUSIONS: We conclude that supplementation and lifestyle changes can effectively impact ALT and AST levels, which can help address liver issues in obese children. However, the evaluation of risk bias, the high heterogeneity, and the bibliometric analysis emphasize the need for more high-quality studies and broader inclusion of diverse child populations to provide better therapeutic recommendations.
    TRIAL REGISTRATION: PROSPERO, CRD42023393952. Registered on January 25, 2023.
    Keywords:  Liver enzymes; MASLD (metabolic dysfunction-associated steatotic liver disease); Meta-analysis; Pediatric NAFLD; Randomized controlled trials; Therapeutic interventions
    DOI:  https://doi.org/10.1186/s12916-024-03744-x
  68. Dent Med Probl. 2024 Nov-Dec;61(6):61(6): 807-808
    "Dental and Medical Problems": Where we are and where we are going.
    Mieszko Więckiewicz, Helena Martynowicz.
      The important thing is not to stop questioning. Curiosity has its own reason for existence. One cannot help but be in awe when he contemplates the mysteries of eternity, of life, of the marvelous structure of reality. It is enough if one tries merely to comprehend a little of this mystery each day.Albert Einstein.
    Keywords:  Dental and Medical Problems; Journal Impact Factor; article; citation; publication
    DOI:  https://doi.org/10.17219/dmp/194670
  69. World Neurosurg. 2024 Nov 19. pii: S1878-8750(24)01886-2. [Epub ahead of print]
    Bibliometric analysis of myelomeningocele management: National disease burden versus publication volume.
    Belinda Shao, Alphadenti Harlyjoy, Olivia A Kozel, Megan Eh Still, Setyo Bp Widodo, Chibueze Agwu, Emilija Sagaityte, Christian Schroeder, Hannah E Gilder, Radzi Hamzah, Felicia W Sun, Joshua R Feler, Santos Santos, Kelsey Sawyer, Konstantina A Svokos, Petra M Klinge, Walter Johnson, Ronnie E Baticulon, Kee B Park.
       BACKGROUND AND OBJECTIVES: Myelomeningocele (MMC) disproportionately affects low-resource areas and regions without mandatory folic acid fortification. No specific literature exists on the distribution of research output regarding neurosurgical management of myelomeningocele worldwide in relation to regional disease burden. We aimed to examine the country of origin and patient population of published papers on myelomeningocele and topics related to neurosurgical management of MMC, to determine whether these were proportionate to disease burden.
    METHOD: A systematic literature search was conducted on neurosurgical aspects of myelomeningocele care. The geographic distribution of neurosurgical MMC research output was examined against the national burden of disease. Bibliometric analysis quantified author and patient country affiliations stratified by World Bank income group classification and folic acid fortification status, juxtaposed with disease burden.
    RESULTS: From 9,692 titles, 1,843 were included, representing 107,446 patients and 2,650 authorship instances. High-income countries (HICs) comprised 3% of 2019's global NTD births, 74% of authorships, and 83% of patients represented. Upper-middle-income countries (UMICs) represented 9% of NTD births, 16% of authorships, and 9% of published patients. Lower-middle-income countries (LMICs) represented 55% of NTD births but only 8.6% of authorships and 7% of patients. Low-income countries (LICs) shouldered 32% of NTD births and contributed 1.3% of authorships and 1.6% of patients. Countries with mandatory folic acid fortification represented 75% of patients and 54% of authorships. Postnatal repair, hydrocephalus, and postoperative complications were the most frequently studied topics.
    CONCLUSION: The global literature concerning neurosurgical management of myelomeningocele originates predominantly from HICs. Published experiences of myelomeningocele patients from LICs/LMICs are scarce, even though they comprise the majority of the affected population. Neurosurgeons and other health professionals must address this mismatch between disease burden and publication volume in order to inform practice, policy, and advocacy for myelomeningocele care worldwide.
    Keywords:  Global pediatric neurousurgery; fetal repair of myelomeningocele; myelomeningocele
    DOI:  https://doi.org/10.1016/j.wneu.2024.11.027
  70. Clin Dermatol. 2024 Nov 19. pii: S0738-081X(24)00247-5. [Epub ahead of print]
    The Evolution of Calcium Alginate-Based Dressings in Wound Healing: A Comprehensive Bibliometric Review of the Top 100 Cited Studies.
    Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Abdullah Farasani, Ahmed Ali Jerah, Saleh M Abdullah, Bassem Oraibi, Yasir Babiker, Hassan Ahmad Alfaifi, Amal Hamdan Alzahrani, Ahmed S Alamer, Tawfeeq Altherwi, Ibrahim Abdel Aziz Ibrahim, Waseem Hassan.
      
    DOI:  https://doi.org/10.1016/j.clindermatol.2024.11.002
  71. J Womens Health (Larchmt). 2024 Nov 18.
    Oncofertility Research: A Review of the Literature.
    Andreea I Dinicu, Emily H Frisch, Hanna Kim, Camilla Yu, Lindsey Beffa, Elliott G Richards.
      Objective: To examine publication trends pertaining to fertility-sparing management in patients of reproductive age with gynecological malignancies. Methods: Ovid MEDLINE was used to aggregate all publications on gynecological cancers and fertility between 1946 and 2022. Original research, reviews, case series/reports, and editorials were included. Publication information was extracted from Ovid MEDLINE. Individual authors' subspecialty credentials were individually reviewed and confirmed. Descriptive statistics were generated. Results: The initial query generated 2,057 publications. Of these, 1,057 (51.4%) publications met search criteria, with the first study being published in 1991 and with 16.6% published in the last 2 years. Only 34 (5.5%) studies were published with collaboration between reproductive endocrinology and infertility (REI) and gynecological oncology physicians in the United States. Gynecological oncologists comprised most senior authors (50.9%), followed by REI specialists (18.6%). Topics of the publications centered on fertility-sparing surgical management (43.1%), medical management of gynecological malignancies (11.3%), and oocyte/ovarian tissue preservation (6.0%). Most publications focused on ovarian malignancies (349, 33.3%), followed by cervical cancer (299, 28.5%), and uterine/endometrial cancer (258, 24.6%). While the number of publications regarding fertility-sparing management has increased over the last 30 years, the majority are retrospective studies and case reports/series. In the last 10 years, only five studies were randomized controlled trials. Conclusions: There is an urgent need for more prospective research in oncofertility. While fertility care in the setting of gynecological cancer is a collaborative effort between the specialties of gynecological oncology and REI, this partnership is not reflected in the authorship of current literature.
    Keywords:  cervical cancer; endometrial cancer; fertility-sparing surgery; fertility-sparing treatment; oncofertility; ovarian cancer; uterine cancer
    DOI:  https://doi.org/10.1089/jwh.2024.0235
  72. Nature. 2024 Nov 20.
    Leading Nature Index science cities in biological sciences: collaboration powers US research.
    Alexia Austin.
      
    Keywords:  Institutions; Publishing; Research data
    DOI:  https://doi.org/10.1038/d41586-024-03526-8
  73. Nature. 2024 Nov 20.
    Leading Nature Index science cities in Earth and environmental science: Research output gathers pace in China.
    Alexia Austin.
      
    Keywords:  Environmental sciences; Institutions; Publishing; Research data
    DOI:  https://doi.org/10.1038/d41586-024-03527-7
  74. Discov Oncol. 2024 Nov 16. 15(1): 665
    Research trends, hotspots and future directions of tertiary lymphoid structures in cancer: a comprehensive informatics analysis and visualization study.
    Chengdong Yu, Jiawei Xu, Siyi Xu, Lei Tang, Qinyuan Han, Zhengkui Sun.
      Many studies have reported the presence of tertiary lymphoid structures (TLSs) in cancer, but the research progress of TLSs in cancer has not been systematically analyzed. Therefore, we analyzed the global scientific knowledge in the field using informatics methods. The results showed that TLSs in cancer have received increasing attention since the 21st century, with an annual publication growth rate of 27.86%. Unsupervised hierarchical clustering based on machine learning further categorized the research features into four clusters, with the cluster related to immunotherapy being considered an emerging cluster. TLSs and immunotherapy were identified as the top two hotspots with the highest occurrence frequency and total link strength. The Walktrap algorithm indicated that "TLSs, carcinoma, prognostic value" and "high endothelial venules, germinal-centers, node-like structures" are important to TLSs but remain underexplored, representing promising research directions. These findings suggest that cancer-related TLSs have brought new insights into antitumor immunity, and targeting TLSs has the potential to transform the landscape of antitumor immunotherapy.
    Keywords:  Cancer; Informatics; Tertiary lymphoid structures; Visualization
    DOI:  https://doi.org/10.1007/s12672-024-01556-2
  75. Science. 2024 Nov 22. 386(6724): 839
    Open-access journal eLife to lose 'impact factor'.
    Jeffrey Brainard.
      Web of Science index pulls metric because of the publisher's unusual peer-review model.
    DOI:  https://doi.org/10.1126/science.adu7465
  76. Sci Rep. 2024 11 19. 14(1): 28576
    China and the U.S. produce more impactful AI research when collaborating together.
    Bedoor AlShebli, Shahan Ali Memon, James A Evans, Talal Rahwan.
      Artificial Intelligence (AI) has become a disruptive technology, promising to grant a significant economic and strategic advantage to nations that harness its power. China, with its recent push towards AI adoption, is challenging the U.S.'s position as the global leader in this field. Given AI's massive potential, as well as the fierce geopolitical tensions between China and the U.S., several recent policies have been put in place to discourage AI scientists from migrating to, or collaborating with, the other nation. Nevertheless, the extent of talent migration and cross-border collaboration are not fully understood. Here, we analyze a dataset of over 350,000 AI scientists and 5,000,000 AI papers. We find that since 2000, China and the U.S. have led the field in terms of impact, novelty, productivity, and workforce. Most AI scientists who move to China come from the U.S., and most who move to the U.S. come from China, highlighting a notable bidirectional talent migration. Moreover, the vast majority of those moving in either direction have Asian ancestry. Upon moving, those scientists continue to collaborate frequently with those in the origin country. Although the number of collaborations between the two countries has increased since the dawn of the millennium, such collaborations continue to be relatively rare. A matching experiment reveals that the two countries have always been more impactful when collaborating than when each works without the other. These findings suggest that instead of suppressing cross-border migration and collaboration between the two nations, the science could benefit from promoting such activities.
    DOI:  https://doi.org/10.1038/s41598-024-79863-5
  77. Nature. 2024 Nov 20.
    Half of the top 20 science cities are now in China - and regional city growth is the key.
    Simon Baker.
      
    Keywords:  Institutions; Publishing; Research data
    DOI:  https://doi.org/10.1038/d41586-024-03521-z
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