bims-evares Biomed News
on Evaluation of research
Issue of 2024–09–15
89 papers selected by
Thomas Krichel, Open Library Society
  1. Letter to the Editor regarding "Trends of impact factor contributors to the Injury Journal: A bibliometric analysis".
  2. Diffusion Magnetic Resonance Imaging and Human Reward System Research: A Bibliometric Analysis and Visualisation of Current Research Trends.
  3. Bibliometric and visualized analysis on hip fracture surgery and venous thromboembolism.
  4. Bibliometric analysis of ophthalmic OCT and OCT angiography research trends over the past 20 years.
  5. Emerging trends and hotspots in peptic ulcer from 2008 to 2023: A bibliometric analysis.
  6. Progressive multiple sclerosis: A bibliometric analysis.
  7. A bibliometric and visual analysis of the research status and hotspots of seborrheic dermatitis based on web of science.
  8. Bibliometric analysis of global research in palliative care for cervical cancer.
  9. Global hotspots and research trends of radiation-induced skin injury: a bibliometric analysis from 2004 to 2023.
  10. Global tendency and research trends of minimally invasive surgery for glaucoma from 1992 to 2023: A visual bibliometric analysis.
  11. Global hotspots and trends in Acanthosis nigricans research: A bibliometric and visualized analysis.
  12. Research status and hotspots in the field of endoplasmic reticulum stress and liver disease: A bibliometric study.
  13. The Most Influential Publications Regarding Hair Transplantation: A Bibliometric Review.
  14. Brain-computer interface for patients with spinal cord injury: A bibliometric study.
  15. Nanomedicine-based cancer immunotherapy: a bibliometric analysis of research progress and prospects.
  16. A bibliometric analysis of cystic fibrosis transmembrane conductance regulators.
  17. Artificial intelligence applications in bone fractures: A bibliometric and science mapping analysis.
  18. The 100 most cited articles about orofacial trauma in children and adolescents: bibliometric analysis.
  19. Immune-inflammatory process in nephrolithiasis: A bibliometric analysis (2000-2023).
  20. Global research trends in transcranial magnetic stimulation for stroke (1994-2023): promising, yet requiring further practice.
  21. Research trends and hotspots on osteoporosis: a decade-long bibliometric and visualization analysis from 2014 to 2023.
  22. Research trends on cancer neuroscience: a bibliometric and visualized analysis.
  23. A global overview of enamel microabrasion for white spot lesions: a bibliometric review.
  24. Global research trends of antibiotic-loaded bone cement: A bibliometric and visualized study.
  25. Scientific research in family medicine in Latin America: A bibliometric analysis.
  26. Research trends on nanomaterials in triple negative breast cancer (TNBC): a bibliometric analysis from 2010 to 2024.
  27. A bibliometric analysis of studies on death anxiety in patients with cancer.
  28. Application of neutrophil to lymphocyte ratio in ankylosing spondylitis: Based on bibliometric and visualization analysis.
  29. Analysis of international publication trends in artificial intelligence in skin cancer.
  30. Artificial intelligence and health information: A bibliometric analysis of three decades of research.
  31. A bibliometric review of Green Tide research between 1995-2023.
  32. Global hotspots and trends of nutritional supplements in sport and exercise from 2000 to 2024: a bibliometric analysis.
  33. Mapping the Nordic Research Landscape for the period 2016-2020: a comprehensive study of research outcomes, collaborations, and impact.
  34. Artificial Intelligence-Related Dental Research: Bibliometric and Altmetric Analysis.
  35. Artificial intelligence empowering rare diseases: a bibliometric perspective over the last two decades.
  36. Research trends on synchronous colorectal cancer with liver metastasis: A bibliometric analysis.
  37. Top 1000 Most Cited Papers in World Neurosurgery.
  38. Robotic surgery in gastric cancer: A bibliometric analysis.
  39. Spotlight on endoplasmic reticulum stress in acute kidney injury: A bibliometric analysis and visualization from 1997 to 2024.
  40. Global trends in acupuncture research: A scientometric analysis from 1980 to 2023.
  41. Association Between Statin Use and Dementia, and Related Mechanisms: A Bibliometric Analysis from 2007 to 2023.
  42. Letter to the Editor Regarding "Bibliometric Analysis of Publications From 2011-2020 in 6 Major Neurosurgical Journals (Part 1): Geographic, Demographic, and Article Type Trends".
  43. Exploring research trends and hotspots on oxidative stress and bronchopulmonary dysplasia: Insights from bibliometric and visualized study.
  44. Study of obesity research using machine learning methods: A bibliometric and visualization analysis from 2004 to 2023.
  45. Bibliometric and visual analyses of research on the links between stroke and exosomes from 2008 to 2023.
  46. Research trends related to emergence agitation in the post-anaesthesia care unit from 2001 to 2023: A bibliometric analysis.
  47. A global bibliometric and visual analysis of research on premature ovarian failure: Based on the perspective of stem cells.
  48. Worldwide research trends concerning operative competence in orthopaedics: A bibliometric and visualization study.
  49. Advancing Research on Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors: A Scientometric Analysis.
  50. Visual Analysis of Hot Topics and Trends in Nutrition for Decompensated Cirrhosis Between 1994 and 2024.
  51. The development of resilience research in critical infrastructure systems: A bibliometric perspective.
  52. Emerging insights into traditional Chinese medicine associated with neurodegenerative diseases: A bibliometric analysis.
  53. Research status and frontiers of renal denervation for hypertension: a bibliometric analysis from 2004 to 2023.
  54. Global trends and hotpots in standardised patients research in the last 30 years: A bibliometric analysis.
  55. Bibliometric analysis of research on spinal cord and sacral neuromodulation in spinal cord injury.
  56. Bibliometric analysis of beneficial cannabis research: Performance analysis and science mapping from 2012 to 2022 and focus on Morocco.
  57. Unlocking the potential of artificial intelligence in reproductive medicine: a bibliometric analysis from 1999 to 2024.
  58. Journal Metrics of the Journal of Craniofacial Surgery: An Analysis Based on the Journal Citation Report 2024.
  59. Bibliometric study of the advances made in clinical dermatological research in Spain from 2015 through 2021: update of the MaIND project and interactive online map.
  60. Research on ovarian cancer stem cells based on bibliometric analysis.
  61. Tracking the trajectory of frankia research through bibliometrics: Trends and future directions.
  62. The Top 20 Cited and Downloaded Red Journal Articles of 2023.
  63. Bibliometric Analyses: Do They Contribute to Knowledge?
  64. Assessing Functional Ankle Instability in Sport: A Critical Review and Bibliometric Analysis.
  65. The mechanisms and drug therapies of colorectal cancer and epigenetics: bibliometrics and visualized analysis.
  66. Sexual Affectivity in Autism Spectrum Disorder: Bibliometric Profile of Scientific Production.
  67. Advances in agar-based composites: A comprehensive review.
  68. Exploring the evolution of research connectivity and funding in global neurosurgical publications.
  69. PUREsuggest: Citation-based Literature Search and Visual Exploration with Keyword-controlled Rankings.
  70. A bibliometric analysis of IoT applications in logistics and supply chain management.
  71. The emerging field of Robo Advisor: A relational analysis.
  72. Current research status and emerging trends in wheat: An integrated scientometric analysis based on ploidy uncovers hidden footprints in the scientific landscape.
  73. A bibliometric review of waste management and innovation: Unveiling trends, knowledge structure and emerging research fronts.
  74. A brief assessment of the influence of Animal Science in the Impact Factor of the AABC.
  75. Intersecting evidence: Bibliometric analysis and clinical trials illuminate immunotherapy in KRAS-mutation cancer: A review.
  76. Content Analysis of the Top 25 Most Cited Articles of the Journal of Craniofacial Surgery With ChatGPT-4o.
  77. The global geography of artificial intelligence in life science research.
  78. The uptake of the international pressure ulcer/injury prevention and treatment guidelines: An updated systematic citation analysis.
  79. Bibliometric, taxonomic, and medicinal perspectives of Ganoderma neo-japonicum Imazeki: A mini review.
  80. Multispectral imaging in medicine: A bibliometric study.
  81. Editorial Commentary: Experts in Shoulder Surgery Do Not Consistently Detect Artificial Intelligence-Generated Scientific Abstracts.
  82. Publication patterns of graduates from a DNP program with submission of a manuscript as a degree requirement.
  83. Do infographics 'spin' the findings of health and medical research?
  84. Behavioral finance in a hundred keywords.
  85. University Rankings in Sport Science: A True Reflection of Excellence?
  86. Response to Letter to the Editor regarding, "The application of 3D printing in dentistry: A bibliometric analysis from 2012 to 2023 (J Prosthet Dent. 2024 Jul 1)".
  87. [Analysis of Clinical-Scientific Research on Diabetes Mellitus in Chile: A 13-Year Study].
  88. Antiviral therapy for COVID-19 virus: A narrative review and bibliometric analysis.
  89. National Institutes of Health Funding Among Society of Asian Academic Surgery Members.
  1. Injury. 2024 Aug 09. pii: S0020-1383(24)00501-1. [Epub ahead of print] 111795
    Letter to the Editor regarding "Trends of impact factor contributors to the Injury Journal: A bibliometric analysis".
    Jorge H Nuñez, Ernesto Guerra-Farfán, Berta Escudero.
      
    Keywords:  Bibliometric; Citation indicator; Impact factor contributor; Injury; Journal impact factor
    DOI:  https://doi.org/10.1016/j.injury.2024.111795
  2. Malays J Med Sci. 2024 Aug;31(4): 111-125
    Diffusion Magnetic Resonance Imaging and Human Reward System Research: A Bibliometric Analysis and Visualisation of Current Research Trends.
    Asma Hayati Ahmad, Siti Hajar Zabri, Siti Mariam Roslan, Nur Ayunie Ayob, Aini Ismafairus Abd Hamid, Nur Hartini Mohd Taib, Nasibah Mohamad, Zahiruddin Othman, Sofina Tamam, Aleya Aziz Marzuki, Rahimah Zakaria.
       Background: The human reward system has been extensively studied using neuroimaging. This bibliometric analysis aimed to determine the global trend in diffusion magnetic resonance imaging (dMRI) and human reward research in terms of the number of documents, the most active countries and their collaborating countries, the top journals and institutions, the most prominent authors and most cited articles, and research hotspots.
    Methods: The research datasets were acquired from the Scopus database. The search terms used were 'reward' AND 'human' AND 'diffusion imaging' OR 'diffusion tensor imaging' OR 'diffusion MRI' OR 'diffusion-weighted imaging' OR 'tractography' in the abstract, article title and keywords. A total of 336 publications were analysed using Harzing's Publish or Perish and VOSviewer software.
    Results: The results revealed an upward trend in the number of publications with the highest number of articles in 2020 and 2022. Most publications were limited to countries, authors, and institutions in the USA, China and Europe. Bracht, Coenen, Wiest, Federspiel and Feng were among the top authors from Switzerland, Germany and the UK. Neuroimage, Neuroimage Clinical, Frontiers in Human Neuroscience, Human Brain Mapping, and the Journal of Neuroscience were the top journals. Among the top articles, six were reviews and four were original articles, while the top keywords in human reward research were 'diffusion MRI', 'adolescence', 'depression' and 'reward-related brain areas'.
    Conclusion: These findings may serve as researchers' references to find collaborative authors, relevant journals, cooperative countries/institutions, and hot topics related to dMRI and reward research.
    Keywords:  bibliometrics; brain; diffusion magnetic resonance imaging; humans; reward
    DOI:  https://doi.org/10.21315/mjms2024.31.4.9
  3. Heliyon. 2024 Aug 30. 10(16): e36222
    Bibliometric and visualized analysis on hip fracture surgery and venous thromboembolism.
    Yiteng Wang, Xin Wang, Zhendong Xu, Zuohong Li.
       Background: Hip fractures primarily occur in older people and represent a significant public health issue due to their high incidence and mortality rate. The concurrent occurrence of venous thromboembolism (VTE) during the perioperative period exacerbates the threat to patient health.
    Methods: We retrieved all articles related to hip fracture surgery and venous VTE from the Web of Science core collection database from 2000 to 2023. For bibliometric analysis, we extracted relevant information, including year of publication, country, institution, journal, impact factor, title, author, category, reference, keywords, number of citations, average number of citations, and H-index.
    Results: A total of 1079 articles were retrieved, with 67 countries, 341 institutions, and 256 journals participating in research on hip fracture surgery and venous thromboembolism. The overall research showed an increasing trend. The United States, Harvard University, Injury-International Journal of The Care of The Injured, and Lassen MR are the leading country, institution, journal, and author respectively, in terms of publication. Research directions in this field mainly include the impact of preoperative anticoagulation on fracture surgery, intraoperative blood protection strategies, and postoperative prevention and treatment of VTE. Hotspots and trends in research include the relationship between direct oral anticoagulants and surgical timing, perioperative blood protection, intertrochanteric fractures, and geriatric traumatic fractures.
    Conclusions: This study constructed the knowledge structure of hip fracture surgery and VTE and identified research hotspots and trends. Future research should focus on developing a prediction system for VTE in hip fracture surgery to guide individualized prevention and treatment.
    Keywords:  Bibliometric analysis; Direct oral anticoagulant; Hip fracture surgery; Intertrochanteric fracture; Venous thromboembolism
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e36222
  4. Int Ophthalmol. 2024 Sep 09. 44(1): 374
    Bibliometric analysis of ophthalmic OCT and OCT angiography research trends over the past 20 years.
    Qian Qian, Jing Wang.
       PURPOSE: Optical coherence tomography (OCT) and OCT angiography (OCTA) are widely used in the diagnosis of ophthalmic diseases. This study aims to provide a comprehensive bibliometric analysis of ophthalmologic OCT and OCT angiography.
    METHODS: We retrieved publications on ophthalmic OCT and OCTA from 2003 to 2022 from the Web of Science Core Collection and used bibliometric tools to analyze and visualize the distribution, trend, and hotspots.
    RESULTS: In total, 20,817 articles written by 48,160 authors from 106 countries were selected. The number of publications has significantly increased. In the last two decades, the USA was the most productive country and received the highest citations. The most productive journal was Investigative Ophthalmology and Visual Science and received the highest number of citations. Moorfields Eye Hospital was the most productive institution. Bandello F published the most papers, while Spaide RF was the highest cited author. SPAIDE RF, 2011, AM J Ophthalmology was the most cited document. "OCT", "glaucoma" and "OCTA" were three hotspots in the last two decades. "Vessel density" and "deep learning" would be research hotspots in the future.
    CONCLUSION: The bibliometric analysis of ophthalmic OCT and OCTA research over the past two decades on keywords, authors, citations, hotspots and trends will provide global researchers with valuable information for future research and cooperation.
    Keywords:  Bibliometric analysis; Ophthalmology; Optical coherence tomography; Optical coherence tomography angiography; Research trend
    DOI:  https://doi.org/10.1007/s10792-024-03292-6
  5. Medicine (Baltimore). 2024 Sep 06. 103(36): e39557
    Emerging trends and hotspots in peptic ulcer from 2008 to 2023: A bibliometric analysis.
    Jiahui Li, Jiamei Jin, Xiaoyang Wang, Fugang Huang, Ke Sun, Menglin Li, Xiaogu Liu.
      Peptic ulcer (PU) is a common digestive disorder in the gastroduodenal. Although bibliometrics has become very popular in the medical field, a bibliometric analysis of research related to PU has yet to be reported. Therefore, this research aims to analyze the trends and hotspots of PU in the last 15 years. Literature data related to PU retrieved from the Web of Science Core Collection database from 2008 to 2023 were visualized and analyzed using CiteSpace 6.1.6.msi, VOSviewer 1.6.19, and SCImago Graphica Beta 1.0.35. Six thousand four hundred ninety-one papers were collected based on inclusion and exclusion criteria. The country with the highest number of publications was China. The institution with the highest number of publications was Baylor College of Medicine. The most prolific author was Yamaoka Yoshio. Malfertheiner Peter had the highest number of citations. The journal with the most publications is World Journal of Gastroenterology. The most cited Journal is Gastroenterology. The most cited reference was published by Marshall B. J. et al in 1984. The article with the highest burst strength was published in 2012 by Malfertheiner Peter. The keyword with the highest burst strength was "oxidative stress." Our research provides a bibliometric analysis of PU research to reveal the trends and hotspots of PU for 2008 to 2023. Our findings will help researchers to quickly understand the current state of research and provide a reference for in-depth studies in this area to foster the development of PU research.
    DOI:  https://doi.org/10.1097/MD.0000000000039557
  6. Medicine (Baltimore). 2024 Sep 06. 103(36): e39034
    Progressive multiple sclerosis: A bibliometric analysis.
    Mays Shawawrah, Saif Aldeen Alryalat.
       BACKGROUND: Progressive multiple sclerosis (MS) is a chronic immune-mediated disease with a poorly understood pathophysiology. This bibliometric analysis of the literature aims to gain an overview of the current state of research on progressive MS.
    METHODS: The Scopus database was searched using the terms "progressive" and "multiple sclerosis" in the title. The search was done till the 7th of January 2023. We analyzed annual trends, countries, institutions, authors, journals, articles, and keywords based primarily on the citation count.
    RESULTS: One thousand nine hundred ninety-one studies out of 1993 search results were included. The included studies had 65,788 citations with a mean of 33 citations per study. Most studies were published between the years 2016 and 2020 (n = 607) with a mean number of 20 citations. The United States of America had the highest number of publications (n = 547) and citations (n = 24,921). The top 3 authors were Thompson A.J., Miller D.H., and Filippi M., and Multiple Sclerosis Journal had the most publications (n = 227) and citations (n = 6849).
    CONCLUSION: To our knowledge, this is the first bibliometric study to address the topic of progressive MS in particular and potentially emphasize the direction of progressive MS research.
    DOI:  https://doi.org/10.1097/MD.0000000000039034
  7. Skin Res Technol. 2024 Sep;30(9): e70048
    A bibliometric and visual analysis of the research status and hotspots of seborrheic dermatitis based on web of science.
    Huixin Yan, Shaobo Zhang, Weichen Sun, Jingnan Li, Jing Xu, Yunpeng Bi, Xingquan Wu, Bailin Song.
       BACKGROUND: Seborrheic dermatitis (SD) is a common chronic inflammatory skin disease. In recent years, significant progress has been made in the field of SD, but there has been no bibliometric research yet. This study aims to use bibliometric methods to analyze the current research status and hot topics of SD, to understand further the research trends and future development prospects in this field.
    METHODS: Retrieve core literature on SD from the Web of Science database and conduct a detailed analysis using CiteSpace and VOSviewer software based on factors such as publication volume, countries (regions), research institutions, journals, authors, highly-cited papers, and keywords.
    RESULTS: From 1996 to 2024, a total of 1436 publications were included in the bibliometric analysis. The number of publications has shown an increasing trend year by year. The USA is the leading country in this field of research. The University of California System is the primary research institution. The International Journal of Dermatology is the journal with the highest number of publications. The author Yang Won Lee has the highest number of publications, while the article "Seborrheic Dermatitis" (2004) by Gupta, A.K. has been cited the most. "Seborrheic dermatitis" is the most frequently occurring keyword. The main research hotspots and frontiers in SD are as follows: (1) The relationship between SD and other skin diseases is a popular research topic; (2) Malassezia and inflammation are current research hotspots in SD; and (3) Focusing on antifungal and anti-inflammatory treatments for SD is the current frontier direction in this field.
    CONCLUSION: This study is a summary of the current status and hot trends of SD research, which helps clinical doctors and researchers quickly understand the insights and valuable information of SD research and provides reference for clinical decision-making and finding future research directions.
    Keywords:  CiteSpace; VOSviewer; bibliometric; seborrheic dermatitis; visual analysis
    DOI:  https://doi.org/10.1111/srt.70048
  8. Front Oncol. 2024 ;14 1432805
    Bibliometric analysis of global research in palliative care for cervical cancer.
    Fhaied Almobarak.
       Objective: The present study aims to conduct a comprehensive bibliometric analysis of global research in palliative care for cervical cancer, providing insights into publication trends, authorship patterns, influential journals, and thematic concentrations.
    Methods: A bibliometric analysis approach was employed using metadata extracted from Scopus spanning 2000-2023. The search utilized main terms related to cervical cancer and palliative care. Data analysis and visualization were performed using the Bibliometrix R Package's web app Biblioshiny and VOSviewer software.
    Results: The study identified 2,492 publications on palliative care for cervical cancer, with a notable peak in 2021. The analysis revealed a diverse publication landscape, encompassing primarily articles. Citation analysis showed a staggering 63,994 citations. The most relevant journals were The Lancet Oncology, Gynecologic Oncology, and International Journal of Gynecological Cancer. The study also highlighted influential authors, institutions, and countries, with Harvard University, the University of Toronto, and the University of Texas MD Anderson Cancer Center leading in publications.
    Discussion: The findings reflected a growing interest in palliative care for cervical cancer, marked by increasing publications over the years. However, the analysis indicated limited international collaborations, with research efforts concentrated in high-income countries. Thematic areas include surgery, palliative care, chemotherapy, radiotherapy, and quality of life. Thus, further collaborations and research in developing countries are needed.
    Conclusion: This bibliometric analysis showcased a comprehensive overview of the global research landscape on palliative care for cervical cancer. The study identified trends, key contributors, and thematic concentrations, offering valuable insights for future research directions and enhancing palliative care services. Addressing the identified gaps, fostering international collaborations, and directing research efforts toward developing countries can contribute to the advancement of palliative care for cervical cancer globally.
    Keywords:  Bibliometrix R Package’s web app Biblioshiny; Scopus; VOSviewer; bibliometric analysis; cervical cancer; palliative care
    DOI:  https://doi.org/10.3389/fonc.2024.1432805
  9. Front Oncol. 2024 ;14 1430802
    Global hotspots and research trends of radiation-induced skin injury: a bibliometric analysis from 2004 to 2023.
    Yungang Hu, Lu Yu, Weili Du, Xiaohua Hu, Yuming Shen.
       Background: Radiation therapy has become an important treatment for many malignant tumours after surgery and for palliative tumour care. Although modern radiotherapy technology is constantly improving, radiation damage to normal tissues is often difficult to avoid, and radiation-induced skin injury (RSI) is a common complication, manifested as skin erythema, peeling, ulceration, and even bone and deep organ damage, seriously affect the quality of life for patients. Basic research and clinical trials related to RSI have achieved certain results, while no researchers have conducted comprehensive bibliometric studies.
    Objective: A comprehensive bibliometric analysis of publications on RSI published between 2004 and 2023 was conducted to identify current hotspots and future directions in this area of study.
    Methods: RSI-related publications published between January 1, 2004, and December 31, 2023, were retrieved from the Web of Science Core Collection (WoSCC) database for analysis using VOSviewer and CiteSpace analytics.
    Results: A total of 1009 publications on RSI from 2004 to 2023 were included in the WoSCC database. The United States had the highest productivity with 299 papers, accounting for 29.63% of the total production, followed by China with 193 papers (19.13%) and Japan with 111 papers (11.00%). In terms of research institutions and journals, the University of Toronto and Journal of Supportive Care in Cancer published the highest number of papers. Professor Edward Chow published the most articles, while Professor Shuyu Zhang was the most cited. The top ten most-cited papers focused on the pathogenesis, prevention, and management of RSI. Keyword co-occurrence analysis and the top 25 keywords with the strongest citation bursts suggest that current research focuses on the pathogenesis, prevention, and treatment management of RSI.
    Conclusion: This study conducted a systematic bibliometric analysis of RSI publications from 2004 to 2023; identified the trends in RSI publications, major research countries, major research institutions, major research journals, major research authors, and major research keywords; and revealed the future development direction and research hotspots of this field. This study provides a valuable reference for future RSI research.
    Keywords:  Citespace; VOSviewer; bibliometric analysis; radiation-induced skin injury; radiotherapy
    DOI:  https://doi.org/10.3389/fonc.2024.1430802
  10. Heliyon. 2024 Aug 30. 10(16): e36591
    Global tendency and research trends of minimally invasive surgery for glaucoma from 1992 to 2023: A visual bibliometric analysis.
    Ruyue Li, Hanruo Liu, Kaiwen Zhang, Zhecheng Lu, Ningli Wang.
       Background: Minimally invasive glaucoma surgery has become a popular research topic over the past decade. However, no published studies have provided a systematic overview for this field. A bibliometric analysis is urgently required to characterise current international trends and provide an intuitive description of past and emerging trends.
    Methods: This study analysed minimally invasive glaucoma surgery-related studies by searching the Web of Science for relevant articles published between 1992 and 2023. All the retrieved titles and abstracts were screened for eligibility, and only articles and reviews written in English were included in the analysis. CiteSpace (version 6.1.6), VOSviewer (version 1.6.19), and the bibliometric package in RStudio were used to construct and visualise the results.
    Results: A total of 1533 publications were included in the analysis with 26072 citations. A total of 4482 authors from 1191 organizations in 57 countries and regions published papers in 139 journals. After 2010, the number of publications increased significantly, with the highest annual productivity occurring in 2022 (n = 229, 15 %). Most of these studies were published in ophthalmology journals. The journal "Ophthalmology" ranked first with 30 papers and 5275 citations. Among the 10 most productive countries, the United States had the largest share of publications (n = 423, 36 %) and Switzerland had the highest proportion of multiple-country publications (70 %). Neodymium was the first keyword discovered, appearing in 1992 and continuing for 21 years. Kahook dual-blade, progression, gonioscopy-assisted transluminal trabeculotomy, efficacy, minimally invasive glaucoma surgery, cataract extraction, and primary open-angle glaucoma were the most recent keywords since 2020.
    Conclusions: This was the first bibliometric analysis of minimally invasive glaucoma surgery and provides an overview of the developments in this field. Our results identified outstanding studies, countries, institutions, journals, and authors in the field to point the way forward for scientific research and clinical applications of minimally invasive glaucoma surgery.
    Keywords:  Bibliometric analysis; Evolution; Glaucoma; Minimally invasive glaucoma surgery
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e36591
  11. Skin Res Technol. 2024 Sep;30(9): e70054
    Global hotspots and trends in Acanthosis nigricans research: A bibliometric and visualized analysis.
    Shaobo Zhang, Huixin Yan, Weichen Sun, Jingnan Li, Jing Xu, Di Cao, Bailin Song, Xingquan Wu.
       BACKGROUND: Acanthosis nigricans (AN) is a common skin disease characterized by clear pigmented patches on the folds of the skin. However, the AN research field lacks scientific and comprehensive bibliometric analysis. This article aims to use bibliometric methods to summarize and visualize the distribution patterns, research hotspots, and development trends of AN literature.
    METHODS: Literature from 1900 to 2024 was retrieved from the Web of Science Core Collection database through AN's thematic search. Using CiteSpace, VOSviewer, and Excel 2019, conduct a comprehensive analysis of the number of publications, countries/regions, institutions, authors, journals, highly cited literature, keywords, and so on, and sort out the hotspots and directions of AN.
    RESULTS: From 1900 to 2024, 1675 publications were included in the bibliometric analysis, showing a steady annual increase in the number of publications. The United States leads in this research field, with the University of Texas System being a key research institution. The Journal of Clinical Endocrinology & Metabolism has the highest number of published papers. The most cited article is "Syndromes of Insulin Resistance and Acanthosis Nigricans: Insulin-Receptor Disorders in Man" (1976). The author Taylor, SI, has published the most papers. "Acanthosis nigricans" is the most frequently occurring keyword. The main research hotspots and frontier areas in AN research are as follows: (1) The relationship between AN and other diseases is a popular research topic; (2) The connection between AN and insulin resistance (IR) is a current research focus; (3) Treatment of AN, with an emphasis on addressing the underlying causes and improving local skin conditions, represents the cutting edge of this field.
    CONCLUSION: This study summarizes the research trends and hotspots in the field of AN, offering valuable information and insights for scholars focused on AN scientific research, and providing a reference for future research directions.
    Keywords:  CiteSpace; VOSviewer; acanthosis nigricans; bibliometric; visual analysis
    DOI:  https://doi.org/10.1111/srt.70054
  12. Medicine (Baltimore). 2024 May 31. 103(22): e38450
    Research status and hotspots in the field of endoplasmic reticulum stress and liver disease: A bibliometric study.
    Ruiyu Wang, Shu Huang, Ping Wang, Xiaowei Tang, Huan Xu, Wei Zhang, Lei Shi, Xiaolin Zhong, Muhan Lü, Xian Zhou, Xiaomin Shi.
      Recently, the study of endoplasmic reticulum stress (ERS) and liver disease has attracted much attention, but bibliometric analysis on this field is scarce. Therefore, to address this gap, we conducted a bibliometric analysis to explore the research status, hotspots, and trends in this field. We searched the Web of Science Core Collection database for publications on ERS and liver disease from 2007 to 2022. Bibliometric online analysis platform, VOSviewer, and CiteSpace were used to perform bibliometric analysis. Two thousand seven hundred fifty-one publications were retrieved form the Web of Science Core Collection database. The USA was the most productive and influential country. Seoul National University, International Journal of Molecular Sciences, and Kaufman RJ were the most productive institution, journal, and author. "Endoplasmic reticulum stress," "nonalcoholic fatty liver disease," "inflammation," "oxidative stress" and "insulin resistance" were the high-frequency keywords, "necrosis factor alpha" was the keywords with the strongest citation bursts, and "nonalcoholic fatty liver," "fibrosis" and "lipid droplet" were the keywords that were still bursting in 2022. The number of publications on ERS and liver disease has increased over the past years. The USA was the most productive and influential country. China has become the country with the largest number of annual publications, but it still needs to work on the quality. ERS and nonalcoholic fatty liver disease, especially the insulin resistance and lipotoxicity in hepatocytes may be the research hotspots and trends in this field of ERS and liver disease.
    DOI:  https://doi.org/10.1097/MD.0000000000038450
  13. Aesthetic Plast Surg. 2024 Sep 13.
    The Most Influential Publications Regarding Hair Transplantation: A Bibliometric Review.
    Juan J Lizardi, Dylan Treger, Savannah C Braud, Tanya Boghosian, Rawan El Abd, Sinan K Jabori, Seth R Thaller.
       INTRODUCTION: This bibliometric review aims to assess the impact of significant publications within the field of hair transplantation. Citation counts will serve as a primary influence indicator.
    METHODS: An exhaustive search was conducted using Clarivate's Web of Science database, yielding 260 publications related to hair transplantation. These were evaluated and sorted based on citations, narrowing down to the 50 most highly cited works for analysis. Parameters including citation density, authorship, institutional affiliations, country of origin, year of publication, article topic, and the level of evidence for each publication were obtained.
    RESULTS: Analyzed publications were cited a total of 1341 times. Authorship analysis revealed that the most significant contributors regarding hair transplantation were Bernstein and Rassman. We also identified the leading institutions affiliated with these works, highlighting the primary academic and research centers driving the field. Geographical analysis exhibited the US' dominance in producing impactful publications. Most publications were also classified within Level IV and Level V according to the Oxford Levels of Evidence system.
    CONCLUSION: This review provides a comprehensive snapshot of the pivotal publications shaping hair transplantation. Our findings underscore significant contributions within this field and may assist researchers and clinicians in understanding the evolution and the current state of the hair transplantation literature. This bibliometric analysis can serve as a roadmap for those seeking to delve into this rapidly evolving field, facilitating the identification of research gaps and formulating future research directions.
    LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  Bibliometric review; Follicular unit extraction; Follicular unit transplant; Hair transplantation surgery
    DOI:  https://doi.org/10.1007/s00266-024-04049-3
  14. World Neurosurg. 2024 Sep 06. pii: S1878-8750(24)01532-8. [Epub ahead of print]
    Brain-computer interface for patients with spinal cord injury: A bibliometric study.
    Jingsheng Feng, Shutao Gao, Yukun Hu, Guangxu Sun, Weibin Sheng.
       BACKGROUND: Spinal cord injury (SCI) is a debilitating condition with profound implications on patients' quality of life (QOL). Recent advancements in brain-computer interface (BCI) technology have provided novel opportunities for individuals with paralysis due to SCI. Consequently, research on the application of BCI for treating SCI has received increasing attention from scholars worldwide. However, there is a lack of rigorous bibliometric studies on the evolution and trends in this field. Hence, the present study aimed to use bibliometric methods to investigate the current status and emerging trends in the field of applying BCI for treating SCI and thus identify novel therapeutic options for SCI.
    METHODS: We conducted a comprehensive review of the relevant literature on BCI application for treating SCI published between 2005 and 2024 by using the Web of Science Core Collection (WoSCC) database. To facilitate visualization and quantitative analysis of the published literature, we used VOSviewer and CiteSpace software tools. These tools enabled the assessment of co-authorships, co-occurrences, citations, and co-citations in the selected literature, thereby providing an overview of the current trends and predictive insights into the field.
    RESULTS: The literature search yielded 714 publications from the WoSCC database. The findings indicated a significant upward trend in the number of publications, yielding a total of 24,804 citations, with an average citation rate of 34.74 per publication and an H-index of 75. Research contributions were identified from 54 countries/regions, and the United States, China, and Germany emerged as the predominant contributors. A total of 1114 research institutions contributed to the retrieved literature, with Harvard Medical School, Brown University, and Northwestern University producing the highest number of publications. The published literature was predominantly distributed across 258 academic journals, and the Journal of Neural Engineering was the most frequently utilized publication source. Hochberg, Leigh, Henderson, Jaimie, and Collinger were the prominent authors in this field.
    CONCLUSION: In recent years, there has been a steep increase in research on the use of BCI for treating SCI. Existing research focuses on the application of BCI for improving rehabilitation and QOL of patients with SCI. Interdisciplinary collaboration is the current trend in this field.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; brain-computer interface; spinal cord injury
    DOI:  https://doi.org/10.1016/j.wneu.2024.08.163
  15. Front Immunol. 2024 ;15 1446532
    Nanomedicine-based cancer immunotherapy: a bibliometric analysis of research progress and prospects.
    Chaofan Chen, Pengfei Yuan, Zhiyun Zhang.
      Despite the increasing number of studies on nanomedicine-based cancer immunotherapy, the overall research trends in this field remain inadequately characterized. This study aims to evaluate the research trends and hotspots in nanomedicine-based cancer immunotherapy through a bibliometric analysis. As of March 31, 2024, relevant publications were retrieved from the Web of Science Core Collection. Analytical tools including VOSviewer, CiteSpace, and an online bibliometric analysis platform were employed. A total of 5,180 publications were analyzed. The study reveals geographical disparities in research output, with China and the United States being the leading contributors. Institutionally, the Chinese Academy of Sciences, University of Chinese Academy of Sciences, and Sichuan University are prominent contributors. Authorship analysis identifies key researchers, with Liu Zhuang being the most prolific author. "ACS Nano" and the "Journal of Controlled Release and Biomaterials" are identified as the leading journals in the field. Frequently occurring keywords include "cancer immunotherapy" and "drug delivery." Emerging frontiers in the field, such as "mRNA vaccine," "sonodynamic therapy," "oral squamous cell carcinoma," "STING pathway,"and "cGAS-STING pathway," are experiencing rapid growth. This study aims to provide new insights to advance scientific research and clinical applications in nanomedicine-based cancer immunotherapy.
    Keywords:  Citespace; VOSviewer; emerging research trends; nano-oncology immunotherapy; visualization analysis
    DOI:  https://doi.org/10.3389/fimmu.2024.1446532
  16. Monaldi Arch Chest Dis. 2024 Jul 24.
    A bibliometric analysis of cystic fibrosis transmembrane conductance regulators.
    Bashar Araiqat, Sebawe Syaj, Aseel Al-Khatib, Nour Al-Bzour, Narmine Hussein, Sarah Aqel, Jamil Ahmad.
      Cystic fibrosis (CF), a multisystem disease primarily affecting the lungs, arises due to pathogenic mutations in the CF transmembrane conductance regulator (CFTR) gene. This study embarked on a bibliometric analysis to survey the use of CFTR modulators in CF treatment. Utilizing the Scopus database, a comprehensive search was executed, incorporating terms related to CF and CFTR modulators. Various document types up to July 19, 2023, were included, with citation counts forming the basis of our analyses. Trends, contributor countries, leading institutions, top authors, journals, keywords, and annual citation trends were evaluated. Our search retrieved 2317 records, predominantly articles. The United States dominated in both publications and citations, followed by the United Kingdom. The University of Alabama, Birmingham, and Vertex Pharmaceuticals, Boston, were among the top institutions. Rowe S.M. was identified as a top-cited author. The Journal of Cystic Fibrosis emerged as the leading journal in terms of publication volume, while the New England Journal of Medicine had the highest citation count. The most-cited article addressed a CFTR potentiator's efficacy in patients with the G551D mutation. The keyword "Cystic fibrosis" appeared most frequently. This bibliometric analysis underscores the significant research focus on CF, especially concerning CFTR modulators. The results highlight the pivotal role of certain countries, institutions, authors, and journals in the progression of CF research, offering insights into current trends and future research directions.
    DOI:  https://doi.org/10.4081/monaldi.2024.3004
  17. Digit Health. 2024 Jan-Dec;10:10 20552076241279238
    Artificial intelligence applications in bone fractures: A bibliometric and science mapping analysis.
    Sen Zhong, Xiaobing Yin, Xiaolan Li, Chaobo Feng, Zhiqiang Gao, Xiang Liao, Sheng Yang, Shisheng He.
       Background: Bone fractures are a common medical issue worldwide, causing a serious economic burden on society. In recent years, the application of artificial intelligence (AI) in the field of fracture has developed rapidly, especially in fracture diagnosis, where AI has shown significant capabilities comparable to those of professional orthopedic surgeons. This study aimed to review the development process and applications of AI in the field of fracture using bibliometric analysis, while analyzing the research hotspots and future trends in the field.
    Materials and methods: Studies on AI and fracture were retrieved from the Web of Science Core Collections since 1990, a retrospective bibliometric and visualized study of the filtered data was conducted through CiteSpace and Bibliometrix R package.
    Results: A total of 1063 publications were included in the analysis, with the annual publication rapidly growing since 2017. China had the most publications, and the United States had the most citations. Technical University of Munich, Germany, had the most publications. Doornberg JN was the most productive author. Most research in this field was published in Scientific Reports. Doi K's 2007 review in Computerized Medical Imaging and Graphics was the most influential paper.
    Conclusion: AI application in fracture has achieved outstanding results and will continue to progress. In this study, we used a bibliometric analysis to assist researchers in understanding the basic knowledge structure, research hotspots, and future trends in this field, to further promote the development of AI applications in fracture.
    Keywords:  Artificial intelligence; CiteSpace; bibliometric; bibliometrix; bone fracture; research trends
    DOI:  https://doi.org/10.1177/20552076241279238
  18. Braz Oral Res. 2024 ;pii: S1806-83242024000105500. [Epub ahead of print]38 e080
    The 100 most cited articles about orofacial trauma in children and adolescents: bibliometric analysis.
    Priscila Seixas Mourão, Izabella Barbosa Fernandes, Gabrielly Fernandes Machado, Rodrigo Galo, Luna Chagas Clementino, Paulo Antônio Martins-Júnior, Maria Letícia Ramos-Jorge.
      This bibliometric study aimed to identify and analyze the 100 most cited articles about orofacial trauma in children and adolescents. The search was conducted in the Web of Science Core Collection (WoS-CC) using a combined search strategy. Two researchers collected the following data from each article: year of publication, country, journal, number and density of citations, author, institutions, study design, type of trauma, and keywords. The VOSviewer and SPSS version 22.0 softwares were used for data analyses. The articles were published from 1968 to 2012 and the number of citations ranged from 49 to 176. Europe was the continent with most articles (40 articles; 3,408 citations). Brazil was the country that made the largest contribution (20 articles; 1,741 citations) and the Universidade do Sul de Santa Catarina (Brazil) was the institution with most articles (5 articles; 492 citations). Marcenes W was the most productive author (8 articles; 968 citations). The cross-sectional study design was the most common (50 articles; 3,978 citations). The most frequent field was epidemiology (73 articles; 5,971 citations). The most widely used criteria for trauma diagnosis were the Andreasen (18 articles; 1,505 citations) and Le Fort (3 articles; 260 citations). Strong positive correlations were found in the number of citations between WoS-CC and Google Scholar (r = 0.929; p < 0.001), WoS-CC and Scopus (r = 0.976; p < 0.001), and Google Scholar and Scopus (r = 0.903; p < 0.001). The 100 most cited articles about orofacial trauma in children and adolescents were mainly cross-sectional studies published by Brazilian authors in epidemiology using Andreasen criteria. Dental Traumatology was the journal with the largest contribution.
    DOI:  https://doi.org/10.1590/1807-3107bor-2024.vol38.0080
  19. Heliyon. 2024 Aug 30. 10(16): e36604
    Immune-inflammatory process in nephrolithiasis: A bibliometric analysis (2000-2023).
    Yunhan Wang, Caitao Dong, Qinhong Jiang, Wenbiao Liao, Sixing Yang.
      The research on the mechanism of nephrolithiasis formation is of great importance due to the fact that the high incidence and recurrence rate of nephrolithiasis bring considerable economic burdens to patients and society. As an important component in the nephrolithiasis formation process, the immune-inflammatory process has been gradually valued by researchers in recent years. In this study, articles related to the immune-inflammatory process of nephrolithiasis published since 2000 were retrieved based on the Web of Science (WoS) database. Eventually, a total of 370 articles were selected for subsequent analyses. Besides, VOSviewer, CiteSpace, and Bibliometrix were employed to quantitatively analyze and visualize the data. The number of articles related to the immune-inflammatory process of nephrolithiasis has increased rapidly in the last five years. From the country level, most articles were contributed by China (n = 140) and the United States (n = 99) contributed the most documents. From the institution level, University of Florida (n = 36) and Nagoya City University (n = 21) had the most articles. From the journal level, Journal of Urology and Urolithiasis published the most articles in this field. Keywords mainly included inflammation, oxidative stress, calcium oxalate, osteopontin, and hyperoxaluria, which represented the research directions in this field. The most productive author was Khan SR (n = 33), whose articles obtained the highest number of citations (2086 times). These efforts may help researchers understand the current progress and status of research on the immune-inflammatory process of nephrolithiasis and identify future research hotspots and directions.
    Keywords:  Bibliometric analysis; Immune; Inflammation; Nephrolithiasis
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e36604
  20. Front Neurol. 2024 ;15 1424545
    Global research trends in transcranial magnetic stimulation for stroke (1994-2023): promising, yet requiring further practice.
    Xin-Yu Li, Rong Hu, Tian-Xiao Lou, Yang Liu, Ling Ding.
       Background: Scholars have been committed to investigating stroke rehabilitation strategies over many years. Since its invention, transcranial magnetic stimulation (TMS) has been increasingly employed in contemporary stroke rehabilitation research. Evidence has shown the significant potential of TMS in stroke research and treatment.
    Objective: This article reviews the research conducted on the use of TMS in stroke from 1994 to 2023. This study applied bibliometric analysis to delineate the current research landscape and to anticipate future research hotspots.
    Method: The study utilized the Web of Science Core Collection to retrieve and acquire literature data. Various software tools, including VOSviewer (version 1.6.19), CiteSpace (version 6.3.R1), Scimago Graphica (version 1.0.36), and WPS (version 11572), were used for data analysis and visualization. The review included analyses of countries, institutions, authors, journals, articles, and keywords.
    Results: A total of 3,425 articles were collected. The top three countries in terms of publication output were the United States (953 articles), China (546 articles), and Germany (424 articles). The United States also had the highest citation counts (56,764 citations), followed by Germany (35,211 citations) and the United Kingdom (32,383 citations). The top three institutions based on the number of publications were Harvard University with 138 articles, the University of Auckland with 81 articles, and University College London with 80 articles. The most prolific authors were Abo, Masahiro with 54 articles, Fregni, Felipe with 53 articles, and Pascual-Leone, Alvaro with 50 articles. The top three journals in terms of article count were Neurorehabilitation and Neural Repair with 139 articles, Clinical Neurophysiology with 128 articles, and Frontiers in Neurology with 110 articles. The most frequently occurring keywords were stroke (1,275 occurrences), transcranial magnetic stimulation (1,119 occurrences), and rehabilitation (420 occurrences).
    Conclusion: The application of TMS in stroke research is rapidly gaining momentum, with the USA leading in publications. Prominent institutions, such as Harvard University and University College London, show potential for collaborative research. The key areas of focus include post-stroke cognitive impairment, aphasia, and dysphagia, which are expected to remain significant hotspots in future research. Future research should involve large-scale, randomized, and controlled trials in these fields. Additionally, identifying more effective combined therapies with rTMS should be a priority.
    Keywords:  bibliometric analysis; cognitive impairment; dysphagia; hotspots; research trends; stroke; transcranial magnetic stimulation
    DOI:  https://doi.org/10.3389/fneur.2024.1424545
  21. Front Med (Lausanne). 2024 ;11 1436486
    Research trends and hotspots on osteoporosis: a decade-long bibliometric and visualization analysis from 2014 to 2023.
    Song Zhang, Ye Liu, Weifeng Yu, Xiyao Gu.
       Background: Osteoporosis is characterized by diminished bone density and quality, compromised bone microstructure, and increased bone fragility, culminating in a heightened risk of fracture. Relatively few attempts have been made to survey the breadth of osteoporosis research using bibliometric approaches. This study aims to delineate the current landscape of osteoporosis research, offering clarity and visualization, while also identifying potential future directions for investigation.
    Methods: We retrieved and filtered articles and reviews pertaining to osteoporosis from the Web of Science Core Collection database, specifically the Science Citation Index Expanded (SCI-E) edition, spanning the years 2014 to 2023. Informatics tools such as CiteSpace and VOSviewer were employed to dissect the intellectual framework, discern trends, and pinpoint focal points of interest within osteoporosis research.
    Results: Our dataset comprised 33,928 osteoporosis-related publications, with a notable surge in annual publication numbers throughout the last decade. China and the United States lead in terms of research output. The University of California System contributed substantially to this body of work, with Amgen demonstrating the highest degree of centrality within the network. Cooper Cyrus emerged as a pivotal figure in the field. An analysis of highly-cited studies, co-citation networks, and keyword co-occurrence revealed that recent years have predominantly concentrated on elucidating mechanisms underlying osteoporosis, as well as its diagnosis, prevention, and treatment strategies. Burst detection analyses of citations and keywords highlighted osteoblasts, sarcopenia, gut microbiota, and denosumab as contemporary hotspots within osteoporosis research.
    Conclusion: This bibliometric analysis has provided a visual representation of the fundamental knowledge structure, prevailing trends, and key focal areas within osteoporosis research. The identification of osteoblasts, sarcopenia, gut microbiota, and denosumab as current hotspots may guide future research endeavors. Continued efforts directed at understanding the mechanisms, fracture outcomes, diagnostics, and therapeutics related to osteoporosis are anticipated to deepen our comprehension of this complex disease.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; cited reference; osteoporosis
    DOI:  https://doi.org/10.3389/fmed.2024.1436486
  22. Front Neurosci. 2024 ;18 1408306
    Research trends on cancer neuroscience: a bibliometric and visualized analysis.
    Xinru Ma, Kun Deng, Yingnan Sun, Minghua Wu.
       Background: Recently, cancer neuroscience has become the focus for scientists. Interactions between the nervous system and cancer (both systemic and local) can regulate tumorigenesis, progression, treatment resistance, compromise of anti-cancer immunity, and provocation of tumor-promoting inflammation. We assessed the related research on cancer neuroscience through bibliometric analysis and explored the research status and hotspots from 2020 to 2024.
    Methods: Publications on cancer neuroscience retrieved from the Web of Science Core Collection. CiteSpace, VOSviewer, and Scimago Graphica were used to analyze and visualize the result.
    Results: A total of 744 publications were retrieved, with an upward trend in the overall number of articles published over the last 5 years. As it has the highest number of publications (n = 242) and citations (average 13.63 citations per article), the United States holds an absolute voice in the field of cancer neuroscience. The most productive organizations and journals were Shanghai Jiaotong University (n = 24) and Cancers (n = 45), respectively. Monje M (H-index = 53), Hondermarck H (H-index = 42), and Amit M (H-index = 39) were the three researchers who have contributed most to the field. From a global perspective, research hotspots in cancer neuroscience comprise nerve/neuron-tumor cell interactions, crosstalk between the nervous system and other components of the tumor microenvironment (such as immune cells), as well as the impact of tumors and tumor therapies on nervous system function.
    Conclusion: The United States and European countries are dominating the field of cancer neuroscience, while developing countries such as China are growing rapidly but with limited impact. The next focal point in this field is likely to be neurotrophic factors. Cancer neuroscience is still in its infancy, which means that many of the interactions and mechanisms between the nervous system and cancer are not yet fully understood. Further investigation is necessary to probe the interactions of the nervous system with cancer cell subpopulations and other components of the tumor microenvironment.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; cancer neuroscience; nervous system
    DOI:  https://doi.org/10.3389/fnins.2024.1408306
  23. Restor Dent Endod. 2024 Aug;49(3): e29
    A global overview of enamel microabrasion for white spot lesions: a bibliometric review.
    Aurélio de Oliveira Rocha, Karina Cardoso, Michely Cristina Goebel, Pablo Silveira Santos, Lucas Menezes Dos Anjos, Juliana Silva Ribeiro, Carla Miranda Santana, Mariane Cardoso.
      This study aimed to identify and analyze articles on enamel microabrasion for the treatment of white spot lesions. A search was conducted on the Web of Science. The following parameters were recorded and analyzed: number of citations, year, journal, impact factor, study design, theme, country and continent, institution, authors, and keywords. Data was analyzed using VOSviewer software. The initial search resulted in 1,126 documents, of which 94 articles were included. The highest number of citations an article received was 65. The oldest article was published in 1975, and the most recent in 2023. The most frequent study design was case report (n = 42). Regarding the themes, it was observed that the main objective of the studies was to evaluate the clinical performance of enamel microabrasion (n = 75), primarily using Opalustre (Ultradent Products Inc., South Jordan, UT, USA) (n = 37) for treating white stains caused by dental fluorosis (n = 41). Most articles originated from Latin America (n = 31), mainly from Brazil (n = 26). The most frequent author was Sundfeld RH (n = 10). This study reveals research trends in the field of enamel microabrasion. The publications were mainly case reports/series using Opalustre for the removal of fluorosis stains.
    Keywords:  Bibliometric analysis; Enamel microabrasion; Esthetic dentistry; Spot lesions
    DOI:  https://doi.org/10.5395/rde.2024.49.e29
  24. Heliyon. 2024 Sep 15. 10(17): e36720
    Global research trends of antibiotic-loaded bone cement: A bibliometric and visualized study.
    Peisheng Chen, Bin Chen, Nannan Liu, Xiaofeng Lin, Xiaojuan Wei, Bin Yu, Xing Teng, Fengfei Lin.
       Objective: Antibiotic-loaded bone cement (ALBC) plays an indispensable role in the treatment of infectious diseases of bone and joint. Here, we intended to analyze the research status, hot spots and frontiers in the field of ALBC, and to provide reference for future research ideas.
    Methods: The related English literature in the field of ALBC in the Web of Science Core Collection database was retrieved from January 1, 2009 to July 11, 2023. VOSviewer was used to extract the information of research constituents or bibliometric items such as authors, institutions, countries, and journals. CiteSpace was used to perform cluster analysis and frontier analysis of key words in ALBC research field.
    Results: A total of 1091 literatures related to ALBC research were retrieved, and the annual number of publications showed a steady upward trend in the past 15 years. The high-yield countries and regions are mainly represented by the United States, China (including Taiwan, China) and several European countries, such as Germany, England, Spain, Italy, the Netherlands, etc. The top three institutions with the highest number of publications were Shanghai Jiao Tong University, Chang Gung University and Chang Gung Memorial Hospital in China. Four of the top 10 influential scholars come from Germany, namely Konstantinos Anagnostakos, Volker Alt, Andrej Trampuz, and Bernd Fink. The top 10 high-yield journals had an average of 25 articles per journal and an average of 618.9 citations. The top 3 high-yield journals were Journal of Arthroplasty (57 articles, 1213 citations), Clinical Orthopaedics and Related Research (35 articles, 1119 times cited), and Journal of Orthopaedic Research (29 papers, 488 times cited). The keywords with high frequency were infection (266 times), vancomycin (239 times), bone-cement (219 times), gentamicin (216 times), antibiotics (168 times), osteomyelitis (163 times), etc. The clustering knowledge map of high-frequency keywords could be divided into 4 categories: (1) elution, release, mechanical and antibacterial properties of ALBC; (2) Application of ALBC in revision of prosthetic joint infections (PJIs); (3) Antibiotic types and application forms of ALBC; (4) Application of ALBC in the treatment of osteomyelitis. The keywords with the strongest citation bursts analysis revealed a core ("replacement/arthroplasty") and two stages of development in the field of ALBC research. The first stage (2009-2018) focused more on ALBC drug delivery, release, and infection prevention, while the second stage (2018-2023) mainly focused on ALBC drug elution, mechanical properties, and PJIs revision. Starting from 2018, the keyword with the strongest citation bursts had shifted from "acrylic bone cement" to "periprosthetic joint infection".
    Conclusion: ALBC research is steadily on the rise. Arthroplasty related applications continue to be the core of ALBC research. The research hotspot and trend are mainly the application in the prevention and treatment of bone and joint infectious diseases and the elution, release, mechanical and antibacterial properties of ALBC.
    Keywords:  Antibiotic-loaded bone cement; Bibliometrics; Fracture-related infections; Polymethylmethacrylate; Prosthetic joint infections; Visualized analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e36720
  25. Aten Primaria. 2024 Sep 12. pii: S0212-6567(24)00232-4. [Epub ahead of print]57(1): 103090
    Scientific research in family medicine in Latin America: A bibliometric analysis.
    Grupo de Investigación de Residentes de Medicina Familiar 2023 IUVA
      
    DOI:  https://doi.org/10.1016/j.aprim.2024.103090
  26. Drug Deliv Transl Res. 2024 Sep 06.
    Research trends on nanomaterials in triple negative breast cancer (TNBC): a bibliometric analysis from 2010 to 2024.
    Hongyi Liang, Guoliang Yin, Dandan Feng, Hanhan Chen, Xiaofei Liu, Jingwei Li.
      Breast cancer (BC) is an important cause of cancer-related death in the world. As a subtype of BC with the worst prognosis, triple-negative breast cancer (TNBC) is a serious threat to human life and health. In recent years, there has been an increasing amount of research aimed at designing and developing nanomaterials for the diagnosis and treatment of TNBC. The purpose of this study was to comprehensively evaluate the current status and trend of the application of nanomaterials in TNBC through bibliometric analysis. Studies focusing on nanomaterials and cancer were searched from the Web of Science core collection (WOSCC) database, and relevant literature meeting the inclusion criteria was selected for inclusion in the study. VOSviewer and CiteSpace were used to perform bibliometric and visual analysis of the included publications. A total of 2338 studies were included. Annual publications have increased from 2010 to 2024. China, the United States and India were the leading countries in the field, accounting for 66.1%, 11.5% and 7.2% of publications, respectively. The Chinese Academy of Sciences and Li Yaping were the most influential institutions and authors, respectively. Journal of Controlled Release was considered the most productive journal. Cancer Research was considered to be the most co-cited journal. Drug delivery and anti-cancer mechanisms related to nanomaterials were considered to be the most widely studied aspects, and green synthesis and anti-cancer mechanisms were also recent research hotspots. In this study, the characteristics of publications were summarized, and the most influential countries, institutions, authors, journals, hot spots and trends in the application of nanomaterials in cancer were identified. These findings provide valuable insights into the current state and future direction of this dynamic field.
    Keywords:  Bibliometric analysis; Breast cancer; Nanomaterials; Research trends; Triple negative
    DOI:  https://doi.org/10.1007/s13346-024-01704-9
  27. J Psychosoc Oncol. 2024 Sep 11. 1-28
    A bibliometric analysis of studies on death anxiety in patients with cancer.
    Wen Li, Hongli Li, Jingcheng Wen, Dong Pang, Yuhan Lu, Hong Yang.
      Purpose: This study evaluates the evolution and focal points of research on death anxiety among cancer patients over the last three decades, utilizing bibliometric analyses.
    Methods: We analyzed publications related to death anxiety among cancer patients from January 1994 to January 2024 using data from the Web of Science Core Collection. Bibliometric indicators such as the number of publications, leading countries, institutions, and research themes were examined.
    Results: A total of 2,602 papers from 286 institutions across 97 countries were identified. There has been a significant increase in research interest, particularly between 2014 and 2023, with a peak in 2022. The United States and Harvard University were found to be the most prolific contributors. Major research themes include quality of life, palliative care, mental health, and cancer-specific concerns.
    Conclusion: The results highlight the rapid development in the field of death anxiety research among cancer patients, with an increase in publications and emerging research themes. However, there is limited international and institutional collaboration. The study underscores the need for enhanced cooperative efforts to advance understanding and research in this area, suggesting directions for future research.
    Keywords:  Bibliometric analysis; death anxiety; patients with cancer
    DOI:  https://doi.org/10.1080/07347332.2024.2398098
  28. Medicine (Baltimore). 2024 May 31. 103(22): e38364
    Application of neutrophil to lymphocyte ratio in ankylosing spondylitis: Based on bibliometric and visualization analysis.
    Cong Chengzhi, Liu Jian, Hu Yuedi, Li Yang, Chen Yiming, Huang Dan.
      Ankylosing spondylitis (AS) as a autoimmune disease involves inflammatory responses in the development of the disease, often causing changes in the neutrophil to lymphocyte ratio (NLR). In the past few decades, research on the relationship between NLR and AS has generally shown an upward trend. This study adopts the bibliometrics method to analyze the development trend, frontier, and hotspots of global research in this field in the past 2 decades. By searching for publications in the SCI-Expanded edition of the Web of Science Core Collection, the information of literature published between 2000 and 2023 is recorded. Based on the VOSviewer, CiteSpace and Excel, bibliometric analysis, and visualization analysis are conducted on the overall distribution of annual output, leading countries, active institutions, journals, authors, co-cited references, and keywords. Through retrieving and screening, a total of 1654 papers are obtained for analysis. In the past 2 decades, the number of publications related to this field has shown an increasing trend. The United States has the highest Hirsch index (H-index) and publication volume. The most productive institution is Harvard University, while the H-index of the University of Milan in Italy is far ahead. Frontiers in Immunology is the institution with the highest output. The H-index of the Annals of the Rheumatic holds the top position. This study has uncovered the main emphasis on NLR in AS research and has provided clarification regarding the value of NLR as a biomarker for immune inflammatory response in the diagnosis and prognosis of AS.
    DOI:  https://doi.org/10.1097/MD.0000000000038364
  29. Clin Dermatol. 2024 Sep 09. pii: S0738-081X(24)00181-0. [Epub ahead of print]
    Analysis of international publication trends in artificial intelligence in skin cancer.
    Lu Yuan, Kai Jin, An Shao, Jia Feng, Caiping Shi, Juan Ye, Andrzej Grzybowski.
      Bibliometric methods were used to analyze publications on artificial intelligence in skin cancer from 2010 to 2022, aiming to explore current publication trends and future directions. A comprehensive search using four terms - "artificial intelligence," "machine learning," "deep learning," and "skin cancer" was performed in the Web of Science database for original English-language publications on artificial intelligence in skin cancer from 2010 to 2022. We visually analyzed publication, citation, and coupling information, focusing on authors, countries and regions, publishing journals, institutions, and core keywords. The analysis of 989 publications revealed a consistent year-on-year increase in publications from 2010 to 2022 (0.51% vs. 33.57%). The USA, India, and China emerged as the leading contributors. IEEE Access was identified as the most prolific journal in this area. Key journals and influential authors were highlighted. Examination of the top 10 most cited publications highlights the significant potential of AI in oncology. Co-citation network analysis identified four primary categories of classical literature on AI in skin tumors. Keyword analysis indicated that "melanoma," "classification," and "deep learning" were the most prevalent keywords, suggesting that deep learning for melanoma diagnosis and grading is the current research focus. The term "pigmented skin lesions" showed the strongest burst and longest duration, while "texture" was the latest emerging keyword. AI represents a rapidly growing area of research in skin cancer with the potential to significantly improve skin cancer management. Future research is likely to focus on machine learning and deep learning technologies for screening and diagnostic purposes.
    Keywords:  artificial intelligence; bibliometric analysis; global publication trend; machine learning; skin cancer
    DOI:  https://doi.org/10.1016/j.clindermatol.2024.09.012
  30. Health Informatics J. 2024 Jul-Sep;30(3):30(3): 14604582241283969
    Artificial intelligence and health information: A bibliometric analysis of three decades of research.
    Elham Aldousari, Dennis Kithinji.
      Information on the application of artificial intelligence (AI) in healthcare is needed to align healthcare transformation efforts. This bibliometric analysis aims to establish the patterns of publication activities on the application of AI in health. A total of 1083 scholarly papers published between 1993 and 2023 were retrieved from the Web of Science and Scopus databases. R Studio and VOSviewer were applied to quantify and illustrate publication patterns and citation rates. Publication rates grew by an average rate of 13% yearly, with each document being cited averagely 12 times. The articles had a mean of five co-authors, with a global co-authorship rate of 10%. COVID-19, artificial intelligence, and machine learning dominated the publications. The US, China, UK, Canada, and India coordinated most of the collaborative research. AI-based health information research is growing steadily. International collaborations can be leveraged to ensure the spread and interoperability of AI-based healthcare innovations globally.
    Keywords:  advanced technologies; analysis; artificial intelligence; bibliometric; big data; deep learning; health informatics; health information; machine learning; publications
    DOI:  https://doi.org/10.1177/14604582241283969
  31. Mar Pollut Bull. 2024 Sep 11. pii: S0025-326X(24)00918-4. [Epub ahead of print]208 116941
    A bibliometric review of Green Tide research between 1995-2023.
    Guanbing Feng, Yinging Zeng, Jingwen Wang, Wei Dai, Fangling Bi, Peiming He, Jianheng Zhang.
      In recent years, the frequent occurrence of green tides has attracted attention from academia and industry. Despite some literature reviews, systematic bibliometric and visualization analyses are still lacking. The study employs CiteSpace and VOSviewer tools to conduct a bibliometric and visualization analysis of green tide-related literature from the Web of Science (1995 to 2023). The study identifies key countries, institutions, journals, disciplines, and authors, and maps out their collaborative networks. Co-citation analysis provides an initial overview of various aspects within the green tide field. Keyword analysis has reveals six core themes: remote sensing applications, eutrophication and green tides, phylogenetic analysis, the impact of climate change, green tide management and applications, and studies focused on green tides in the China Sea. Additionally, keyword burst analysis has revealed two emerging trends. This study provides a strategic framework for future research, serving as a navigational guide in the field of green tide studies.
    Keywords:  Bibliometric; CiteSpace; Green tide; VOSviewer; Visual analysis
    DOI:  https://doi.org/10.1016/j.marpolbul.2024.116941
  32. J Health Popul Nutr. 2024 Sep 12. 43(1): 146
    Global hotspots and trends of nutritional supplements in sport and exercise from 2000 to 2024: a bibliometric analysis.
    Te Fu, Haitao Liu, Chaofan Shi, Haichang Zhao, Feiyue Liu, Yingjian Xia.
       BACKGROUND: Nutritional supplements for sports and exercise (NSSE) can facilitate the exogenous replenishment of the body. This study provides the first extensive overview of NSSE research through bibliometric and visual analyses.
    METHODS: We searched the Web of Science Core Collection database for literature related to "NSSE" from 1st January 2000 to 8th March 2024. A total of 1744 articles were included. CiteSpace, VOSviewer, and Bibliometrix R package software were used to analyze the data.
    RESULTS: Research in the NSSE can be divided into steady growth, exponential growth, fluctuating stage, and surge stages. The United States is the most active country in this field. In recent years, the leading countries have been Croatia, Colombia, Slovenia, Chile, Egypt, China, and Thailand. The Australian Institute of Sports is the top research institution in terms of number of publications. Burke, LM from Australia published the most articles. Research in this area has primarily been published in Nutrients in Switzerland. The study population mainly consisted of men, and postmenopausal women were the main focus of the female group. Coronary heart and cardiovascular diseases continue to dominate research.
    CONCLUSION: Research on the NSSE is developing rapidly, with an annual growth trend. Insulin resistance, sports nutrition, inflammation, alpha-linolenic acid, limb strength performance, female sex, and gut microbiota are the focus of the current research and trends for future research. Future research should focus on improving the scientific training system for athletes and quality of training and life for the general public.
    Keywords:  Bibliometric analysis; Dietary supplements; Exercise; Nutritional supplements; Sport
    DOI:  https://doi.org/10.1186/s41043-024-00638-9
  33. F1000Res. 2024 ;13 71
    Mapping the Nordic Research Landscape for the period 2016-2020: a comprehensive study of research outcomes, collaborations, and impact.
    Aparna Narayan, Bharti Chogtu, Manthan Janodia, Raghu Radhakrishnan, Santhosh K Venkata.
       Background: This article aims to study the research outcomes of five Nordic countries in terms of research publications, spend on R&D, outcomes and collaborations as these are important parameters to understand research thrust of the countries/regions, in addition to their innovation capability.
    Methods: The research outcomes of the Nordic countries in terms of the total number of publications, coauthored publications, publications with corporate collaborators, citations, the Field Weighted Citation Index (FWCI) and publications in different subject areas were retrieved using Scopus and its associate SciVal. The research outcomes were extracted for five years from 2016-2020. In addition, total population, researcher population and research spend of these countries have been obtained from World Bank data available for the year 2021.
    Results: The analysis showed that Sweden has the highest population and the highest number of researchers in this region. All countries have the highest number of coauthored publications with the United States, followed by the United Kingdom, except Iceland, which has the second highest number of coauthored publications with Sweden. Denmark, followed by Iceland, stands prominent with reference to having publications with corporate collaborations. Denmark and Sweden have a high percentage of articles in first quartile journals, which is above the average for Nordic countries. Iceland stands at the top with the highest citations, which is depicted by high FWCI. Across subject areas, the Nordic countries have maximum publications in life sciences. Other prominent subject areas include technology and natural sciences.
    Conclusion: On analysing the research landscape of Nordic countries, maximum research output is in the field of life sciences and medicine, and most of the coauthored publications of these countries are with the United States. Denmark, with its exemplary research output, excels with maximum papers in top quartile journals and with maximum corporate collaborations and the highest FWCI.
    Keywords:  Bibliometric; Nordic countries; Research; Subject profile
    DOI:  https://doi.org/10.12688/f1000research.144036.2
  34. Int Dent J. 2024 Sep 11. pii: S0020-6539(24)01415-1. [Epub ahead of print]
    Artificial Intelligence-Related Dental Research: Bibliometric and Altmetric Analysis.
    Wei Lu, Xueqian Yu, Yueyang Li, Yi Cao, Yanning Chen, Fang Hua.
       BACKGROUND: Recent years have witnessed an explosive surge in dental research related to artificial intelligence (AI). These applications have optimised dental workflows, demonstrating significant clinical importance. Understanding the current landscape and trends of this topic is crucial for both clinicians and researchers to utilise and advance this technology. However, a comprehensive scientometric study regarding this field had yet to be performed.
    METHODS: A literature search was conducted in the Web of Science Core Collection database to identify eligible "research articles" and "reviews." Literature screening and exclusion were performed by 2 investigators. Thereafter, VOSviewer was utilised in co-occurrence analysis and CiteSpace in co-citation analysis. R package Bibliometrix was employed to automatically calculate scientific impacts, determining the core authors and journals. Altmetric data were described narratively and supplemented with Spearman correlation analysis.
    RESULTS: A total of 1558 research publications were included. During the past 5 years, AI-related dental publications drastically increased in number, from 36 to 581. Diagnostics and Scientific Reports published the most articles, whereas Journal of Dental Research received the highest number of citations per article. China, the US, and South Korea emerged as the most prolific countries, whilst Germany received the highest number of citations per article (23.29). Charité Universitätsmedizin Berlin was the institution with the highest number of publications and citations per article (29.16). Altmetric Attention Score was correlated with News Mentions (P < .001), and significant associations were observed amongst Dimension Citations, Mendeley Readers, and Web of Science Citations (P < .001).
    CONCLUSIONS: The publication numbers regarding AI-related dental research have been rising rapidly and may continue their upwards trend. China, the US, South Korea, and Germany had promoted the progress of AI-related dental research. Disease diagnosis, orthodontic applications, and morphology segmentation were current hotspots. Attention mechanism, explainable AI, multimodal data fusion, and AI-generated text assistants necessitate future research and exploration.
    Keywords:  Artificial intelligence; Bibliometrics; Deep learning; Dental research; Machine learning
    DOI:  https://doi.org/10.1016/j.identj.2024.08.004
  35. Orphanet J Rare Dis. 2024 Sep 13. 19(1): 345
    Artificial intelligence empowering rare diseases: a bibliometric perspective over the last two decades.
    Peiling Ou, Ru Wen, Linfeng Shi, Jian Wang, Chen Liu.
       OBJECTIVE: To conduct a comprehensive bibliometric analysis of the application of artificial intelligence (AI) in Rare diseases (RDs), with a focus on analyzing publication output, identifying leading contributors by country, assessing the extent of international collaboration, tracking the emergence of research hotspots, and detecting trends through keyword bursts.
    METHODS: In this bibliometric study, we identified and retrieved publications on AI applications in RDs spanning 2003 to 2023 from the Web of Science (WoS). We conducted a global research landscape analysis and utilized CiteSpace to perform keyword clustering and burst detection in this field.
    RESULTS: A total of 1501 publications were included in this study. The evolution of AI applications in RDs progressed through three stages: the start-up period (2003-2010), the steady development period (2011-2018), and the accelerated growth period (2019-2023), reflecting this field's increasing importance and impact at the time of the study. These studies originated from 85 countries, with the United States as the leading contributor. "Mutation", "Diagnosis", and "Management" were the top three keywords with high frequency. Keyword clustering analysis identified gene identification, effective management, and personalized treatment as three primary research areas of AI applications in RDs. Furthermore, the keyword burst detection indicated a growing interest in the areas of "biomarker", "predictive model", and "data mining", highlighting their potential to shape future research directions.
    CONCLUSIONS: Over two decades, research on the AI applications in RDs has made remarkable progress and shown promising results in the development. Advancing international transboundary cooperation is essential moving forward. Utilizing AI will play a more crucial role across the spectrum of RDs management, encompassing rapid diagnosis, personalized treatment, drug development, data integration and sharing, and continuous monitoring and care.
    Keywords:  Artificial intelligence; Bibliometric analysis; Medical informatics; Rare diseases
    DOI:  https://doi.org/10.1186/s13023-024-03352-1
  36. Asian J Surg. 2024 Sep 11. pii: S1015-9584(24)02046-3. [Epub ahead of print]
    Research trends on synchronous colorectal cancer with liver metastasis: A bibliometric analysis.
    HaoNan Kang, GuoYi Wen, Yang Xu, Xin Chen.
      
    Keywords:  Bibliometric analysis; Citespace; Synchronous colorectal cancer with liver metastasis; Vosviewer
    DOI:  https://doi.org/10.1016/j.asjsur.2024.07.354
  37. World Neurosurg. 2024 Sep 05. pii: S1878-8750(24)01530-4. [Epub ahead of print]
    Top 1000 Most Cited Papers in World Neurosurgery.
    Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Abdullah Farasani, Ahmed Ali Jerah, Saleh M Abdullah, Ieman A Aljahdali, Bassem Oraibi, Hassan Ahmad Alfaifi, Amal Hamdan Alzahrani, Omar Oraibi, Yasir Babiker, Waseem Hassan.
       BACKGROUND: Over the past 15 years, World Neurosurgery (WN) has emerged as a pivotal source in the neurosurgery field, reflecting remarkable growth and development. Originally published as Surgical Neurology from 1973 to 2009, the journal transitioned to its current title in 2010, significantly expanding its reach and influence.
    METHODS: A comprehensive bibliometric analysis of WN's publications from 1973 to 2023 was performed. The analysis focused on identifying the top authors, universities, countries, and sponsors in two periods: 1973-2009 and 2010-2023. Additionally, the study included a detailed examination of the top 1,000 most cited papers, and summary of top 10 most cited papers.
    RESULTS: The analysis revealed that during the Surgical Neurology period, 6,567 research documents were published, including 6,503 articles and 64 reviews. Since rebranding as World Neurosurgery, the journal has published an additional 17,663 documents, comprising 15,366 articles and 2,297 reviews up to 2023. The top contributors (authors, universities, and sponsors) were identified, and the study found that WN has successfully increased its foothold across various continents. The co-word analysis provided insights into the thematic focus of the top 1,000 most cited papers, categorizing them into 15 distinct areas.
    CONCLUSION: This study underscores World Neurosurgery's significant role in advancing neurosurgical research over the past five decades. The findings highlight the journal's evolution, its expanding global influence, and the key contributors to its success.
    Keywords:  Bibliometrics; Co-words analysis; Scopus; Top 1000 Most Cited Papers; World Neurosurgery
    DOI:  https://doi.org/10.1016/j.wneu.2024.08.161
  38. Asian J Surg. 2024 Sep 06. pii: S1015-9584(24)01864-5. [Epub ahead of print]
    Robotic surgery in gastric cancer: A bibliometric analysis.
    Jinpeng Yuan, Chanping Yang, Zixiang Chen, Jiarui Lin.
      
    Keywords:  Bibliometric analysis; Gastric cancer; Robotic surgery
    DOI:  https://doi.org/10.1016/j.asjsur.2024.08.124
  39. Medicine (Baltimore). 2024 Sep 06. 103(36): e39567
    Spotlight on endoplasmic reticulum stress in acute kidney injury: A bibliometric analysis and visualization from 1997 to 2024.
    Yuan Yang, Fang Yuan, Debiao Xiang, Pengkai Wang, Rui Yang, Xin Li.
       BACKGROUND: Endoplasmic reticulum (ER) stress, a protective stress response of body and play important role in maintain ER stability. Acute kidney injury (AKI) is a severe syndrome, and the molecular mechanisms of AKI has not been fully elucidated. With an increasing understanding of ER stress, ER stress has been investigated and considered a potential and novel therapeutic target in AKI. This study aims to employ a bibliometric approach to analyze research trends and focal points in ER stress associated with AKI over 3 decades.
    METHODS: Data were retrieved from the Web of Science Core Collection on April 15, 2024. CiteSpace and VOSviewer bibliometric software were mainly used to measure bibliometrics and analyze knowledge graphs to predict the latest research trends in the field.
    RESULTS: There were 452 "ER stress in AKI" articles in the Web of Science Core Collection. According to the report, China and the United States were the leading research drivers in this field. Central South University was the most active academic institution, contributing the most documents. In this field, Dong Zheng was the most prolific author. The American Journal of Physiology-Renal Physiology was the journal with the most records among all journals. The keywords "NLRP3 inflammasome," "redox signaling," and novel forms of cell death such as "ferroptosis" may represent current research trends and directions.
    CONCLUSION: The bibliometric analysis comprehensively examines the trends and hotspots on "ER stress and AKI." Studies on AKI related to stress in the ER are still in their infancy. Research should focus on understanding the relationship between ER stress and inflammasome, redox signal pathways and new forms of cell death such as ferroptosis.
    DOI:  https://doi.org/10.1097/MD.0000000000039567
  40. Medicine (Baltimore). 2024 Sep 06. 103(36): e39549
    Global trends in acupuncture research: A scientometric analysis from 1980 to 2023.
    Coşkun Öztekin, Aynure Öztekin.
      The objective of this study was to examine articles on acupuncture from past to present, revealing prevalent research trends, showcasing global productivity, identifying international collaborations, and highlighting influential publications and journals in the field. We acquired a comprehensive dataset comprising 9340 articles pertaining to acupuncture that were published within the time frame spanning from 1980 to 2023. These articles were sourced from the Web of Science and underwent rigorous analysis through a diverse set of bibliometric techniques. Our analytical approaches encompassed trend keyword analysis, thematic evolution analysis, conceptual structure analysis, factor analysis, citation and co-citation analyses, as well as an exploration of international collaboration patterns. The 3 most productive countries were China (n = 3357), the USA (n = 1351), and South Korea (n = 814). The 3 most productive journals were Acupuncture in Medicine (n = 440), Evidence Based Complementary and Alternative Medicine (n = 415), and Medical Acupuncture (n = 400). The 3 journals with the highest h-index on acupuncture were the Journal of Alternative and Complementary Medicine (h = 45), Pain (h = 41), and the American Journal of Chinese Medicine (h = 35). The most active author was Park Hi-Joon (n = 128). According to the findings of the factor analysis, acupuncture literature was grouped around 3 main subfactors. The primary factor encompassed topics related to the effectiveness/applicability of the treatment method for various medical conditions and general principles of acupuncture methods and points. The second factor covered topics related to mental health and quality of life. The third subfactor addressed the qualitative and quantitative analysis direction of acupuncture, such as meta-analysis and systematic reviews, and randomized controlled trials. From the past to the present, the most extensively researched main topics in acupuncture literature have covered a wide range of subjects. Prominent themes among these topics included acupuncture methods and applications, pain management, the nervous system and acupuncture, mental health and acupuncture, quality of life, and general health. In recent years, emerging trends in acupuncture research have focused on neurological health issues, oncology and cancer treatment, women's health and hormonal issues, sleep problems, digestive issues, and studies related to the quantitative and qualitative evaluation of acupuncture research.
    DOI:  https://doi.org/10.1097/MD.0000000000039549
  41. J Alzheimers Dis. 2024 Sep 11.
    Association Between Statin Use and Dementia, and Related Mechanisms: A Bibliometric Analysis from 2007 to 2023.
    Xian-Zheng Sang, Wen Chen, Xiao-Xiang Hou, Chun-Hui Wang, Dan-Feng Zhang, Li-Jun Hou.
       Background: Emerging evidence suggests the potential of hydroxymethylglutaryl-coenzyme A (HMG-CoA, statins) as a therapeutic option for dementia.
    Objective: The primary objective of this study is to assess the current state of research on statins use in dementia, with a focus on identifying pivotal questions within the field.
    Methods: A systemic search for publications on statin use in dementia between 2007 and 2023 was conducted, utilizing the Web of Science Core Collection. The scientific output was analyzed from various perspectives through VOSviewer, CiteSpace, and the bibliometrics website (https://bibliometric.com/).
    Results: 560 articles authored by 2,977 individuals and 999 institutions across 58 countries were included, which were published in 295 periodicals and cited 21,176 references from 16,424 authors. The annual publication output remained steady, while the number of citations increased consistently. The U.S. and Mayo Clinic emerged as the most significant country and institution, respectively. B. McGuinness and D.L. Sparks were the most eminent authors. Journal of Alzheimer's Disease was the most influential journal. Three sets of keywords and the top 10 references were identified, suggesting pivotal questions within the field.
    Conclusions: While statins show promising potential as a treatment option for dementia, their use remains uncertain due to the reported short-term cognitive impairment events and questionable long-term protective effects against dementia. The pivotal question is to ascertain the association between statins and cognition. The mechanisms underlying the effects of statins on cognition are multifaceted. This study provides insights into the current status within the field of statin use in dementia.
    Keywords:  Alzheimer’s disease; association; bibliometrics; dementia; hydroxymethylglutaryl-CoA reductase inhibitors; mechanism; statins; vascular dementia
    DOI:  https://doi.org/10.3233/JAD-240270
  42. World Neurosurg. 2024 Sep;pii: S1878-8750(24)00752-6. [Epub ahead of print]189 530-548
    Letter to the Editor Regarding "Bibliometric Analysis of Publications From 2011-2020 in 6 Major Neurosurgical Journals (Part 1): Geographic, Demographic, and Article Type Trends".
    Waseem Hassan, Mehreen Zafar, Maryam Jan, Antonia Eliene Duarte.
      
    DOI:  https://doi.org/10.1016/j.wneu.2024.04.178
  43. Pediatr Pulmonol. 2024 Sep 12.
    Exploring research trends and hotspots on oxidative stress and bronchopulmonary dysplasia: Insights from bibliometric and visualized study.
    Liyan Luo, Yuan Li, Zhi Long, Feng Jiang, Fang Wu, Qian Wang.
       BACKGROUND: Bronchopulmonary dysplasia (BPD) is a severe chronic lung disease primarily affecting premature infants, often resulting from prolonged mechanical ventilation and oxygen therapy. Oxidative stress plays a critical role in the pathogenesis of BPD, contributing to lung injury, inflammation, and impaired lung development. Despite extensive research, there is a need to systematically map out the research trends and hotspots in this field to inform future studies and therapeutic strategies.
    METHODS: This study utilized bibliometric and visualized analysis to explore global research trends and hotspots on oxidative stress and BPD from 2004 to 2024. A comprehensive literature search was conducted in the Web of Science Core Collection, focusing on publications related to oxidative stress and BPD. Tools such as VOSviewer, Citespace, and the R package Bibliometrix were employed to analyze Coauthorship, co-citation, and keyword co-occurrence networks, as well as to identify emerging research fronts and influential studies.
    RESULTS: The analysis identified 597 relevant publications, showing a steady increase in research output over the 20-year period, with a significant surge in the last decade. The United States led in research contributions, followed by China and Germany, with notable collaborations among these countries. Coauthorship analysis highlighted key research institutions, such as Harvard University and the University of California, as central nodes in the research network. Thematic clustering revealed five major research areas: antioxidant mechanisms, inflammation, molecular pathways, lung development, and therapeutic interventions. The keyword co-occurrence analysis showed a shift in research focus over time. Early studies concentrated on basic pathophysiological mechanisms, while recent research has increasingly focused on advanced molecular techniques, such as gene expression and targeted therapies. Notably, the study identified emerging research hotspots, including the role of extracellular vesicles and cellular senescence in BPD, as well as the potential therapeutic applications of antioxidants like superoxide dismutase mimetics.
    CONCLUSION: This bibliometric study provides a comprehensive overview of the research landscape on oxidative stress and BPD, identifying key trends, influential authors, and emerging research topics. The findings underscore the importance of continued research in this field, particularly in translating basic scientific insights into clinical applications to improve outcomes for infants affected by BPD. The study also highlights potential areas for future investigation, including the development of novel therapeutic strategies targeting oxidative stress in BPD.
    Keywords:  bibliometric analysis; bronchopulmonary dysplasia; citespace; oxidative stress; premature infants
    DOI:  https://doi.org/10.1002/ppul.27268
  44. Medicine (Baltimore). 2024 Sep 06. 103(36): e39610
    Study of obesity research using machine learning methods: A bibliometric and visualization analysis from 2004 to 2023.
    Xiao-Wei Gong, Si-Yu Bai, En-Ze Lei, Lian-Mei Lin, Yao Chen, Jian-Zhong Liu.
       BACKGROUND: Obesity, a multifactorial and complex health condition, has emerged as a significant global public health concern. Integrating machine learning techniques into obesity research offers great promise as an interdisciplinary field, particularly in the screening, diagnosis, and analysis of obesity. Nevertheless, the publications on using machine learning methods in obesity research have not been systematically evaluated. Hence, this study aimed to quantitatively examine, visualize, and analyze the publications concerning the use of machine learning methods in obesity research by means of bibliometrics.
    METHODS: The Web of Science core collection was the primary database source for this study, which collected publications on obesity research using machine learning methods over the last 20 years from January 1, 2004, to December 31, 2023. Only articles and reviews that fit the criteria were selected for bibliometric analysis, and in terms of language, only English was accepted. VOSviewer, CiteSpace, and Excel were the primary software utilized.
    RESULTS: Between 2004 and 2023, the number of publications on obesity research using machine learning methods increased exponentially. Eventually, 3286 publications that met the eligibility criteria were searched. According to the collaborative network analysis, the United States has the greatest volume of publications, indicating a significant influence on this research. coauthor's analysis showed the authoritative one in this field is Leo Breiman. Scientific Reports is the most widely published journal. The most referenced publication is "R: a language and environment for statistical computing." An analysis of keywords shows that deep learning, support vector machines, predictive models, gut microbiota, energy expenditure, and genome are hot topics in this field. Future research directions may include the relationship between obesity and its consequences, such as diabetic retinopathy, as well as the interaction between obesity and epidemiology, such as COVID-19.
    CONCLUSION: Utilizing bibliometrics as a research tool and methodology, this study, for the first time, reveals the intrinsic relationship and developmental pattern among obesity research using machine learning methods, which provides academic references for clinicians and researchers in understanding the hotspots and cutting-edge issues as well as the developmental trend in this field to detect patients' obesity problems early and develop personalized treatment plans.
    DOI:  https://doi.org/10.1097/MD.0000000000039610
  45. Medicine (Baltimore). 2024 Sep 06. 103(36): e39498
    Bibliometric and visual analyses of research on the links between stroke and exosomes from 2008 to 2023.
    Jiaqi Song, Kaihan Zhan, Jiayu Li, Saiqi Cheng, Xiaohong Li, Li Yu.
      Exosomes, which are extracellular vesicles secreted and released from specific cells, exist widely in cell culture supernatants and various body fluids. This study aimed to analyze the research status of exosomes in stroke, and predict developmental trends via bibliometric analyses. The related literature from January 1, 2008 to January 1, 2024 was searched in the Web of Science Core Collection and 943 articles were retrieved. VOSviewer was used to visualize national cooperation and institutional cooperation. Cluster analysis of keywords and Citespace were applied for mutation analysis. Results: The analysis of 943 works of literature showed that the number of published articles has been steadily increasing since 2015. It is predicted that nearly 211 articles will be published in 2024 and 220 annually by 2028. China has the largest number of publications (473), followed by the United States (234), and Germany (61). The institution with the most publications is Henry Ford Hospital (Detroit, MI). In the keyword cluster "Exosomes and the Mechanism of Stroke: Inflammation and Apoptosis," exosomes and inflammation were identified as hotspots. "Functional recovery" was a new trend in the keyword cluster of "Angiogenesis and Functional Recovery after Stroke." China and the United States are the main forces in this field, and both countries focusing on drug treatments. The studies have been published mainly in China and United States. The findings of our bibliometric analyses of the literature may enable researchers to choose appropriate institutions, collaborators, and journals.
    DOI:  https://doi.org/10.1097/MD.0000000000039498
  46. Open Med (Wars). 2024 ;19(1): 20241021
    Research trends related to emergence agitation in the post-anaesthesia care unit from 2001 to 2023: A bibliometric analysis.
    Lulu Cao, Yunhong Ren, Fang Wen, Juan Du, Mei He, Huaping Huang.
       Background: Emergence agitation (EA) is a behavioural disturbance encountered during the recovery phase of patients following general anaesthesia. It is characterised by restlessness, involuntary limb movements, and drainage tube withdrawal and may significantly harm patients and medical staff. The mechanism of EA has not been fully understood and is still a challenging subject for researchers.
    Methods: We extracted relevant publications published between 1 January 2001 and 31 December 2023 on the Web of Science Core Collection platform. VOSviewer software was utilised to analyse the retrieved literature and predict the development trends and hotspots in the field.
    Results: The results show that the number of publications grew annually, with China contributing the most, followed by the United States and South Korea. The co-occurrence of keywords "children," "propofol," "risk factors" are current research hotspots. Owing to its self-limiting and short-duration characteristics, EA lacks standardised clinical time guidelines and objective assessment tools, which may be the focus of future research in this field.
    Conclusions: Understanding the research hotspots and the latest progress in this field, this study will help to continuously improve the clinical understanding and management of EA, and help to timely identify environmental risk factors for EA in clinical practice.
    Keywords:  VOSviewer; Web of Science Core Collection; bibliometric analysis; emergence agitation; global trends
    DOI:  https://doi.org/10.1515/med-2024-1021
  47. Medicine (Baltimore). 2024 May 31. 103(22): e38399
    A global bibliometric and visual analysis of research on premature ovarian failure: Based on the perspective of stem cells.
    Zhiguo Xu, Yi Zhu, Lefeng Liu, Chao Liu, Zhilong Dong.
      Premature ovarian failure (POF), a condition influenced by genetic and immune factors, remains incurable despite years of intensive research and significant efforts. This persisting challenge underscores the urgency to address this escalating health concern. Fortunately, stem cell regenerative medicine has emerged as a promising avenue for developing therapeutic strategies and innovative treatments for POF. Bibliometric analysis, renowned for its objectivity, systematic approach, and comprehensive coverage of a given field, has yet to be applied to the study of stem cell research in POF. This study used CiteSpace software to assess contributions and co-occurrence relationships among various countries/regions, institutes, journals, and authors. This approach also allowed us to identify research hotspots and promising future trends within this field. Additionally, we generated visualizing maps utilizing the Web of Science Core Collection (WOSCC) and PubMed publications. By providing valuable information and references, we aim to enhance the understanding of the challenges involved in translating stem cell regeneration into clinical therapeutic potential for POF. Furthermore, our analysis and findings guide researchers and clinicians, facilitating future collaborative research and clinical intervention efforts.
    DOI:  https://doi.org/10.1097/MD.0000000000038399
  48. Asian J Surg. 2024 Sep 10. pii: S1015-9584(24)01872-4. [Epub ahead of print]
    Worldwide research trends concerning operative competence in orthopaedics: A bibliometric and visualization study.
    Xing Zhao, Shayom Debopadhaya, Paul Toogood, Meir T Marmor.
      
    Keywords:  Bibliometric analysis; Citations; Competence; Orthopaedics; Simulation; Training
    DOI:  https://doi.org/10.1016/j.asjsur.2024.08.132
  49. Malays J Med Sci. 2024 Aug;31(4): 14-34
    Advancing Research on Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors: A Scientometric Analysis.
    Abdul Matin, Gul-E-Saba Chaudhry, Mohamad Nor Azra, Mohamad Gazali, Yik Sung Yeong, Tengku Sifzizul Tengku Muhammad.
      Atherosclerosis is characterised by the accumulation of fatty deposits and plaque as a result of a continuously high level of low-density lipoprotein cholesterol (LDL-C) in the blood. The primary objective of this research is to assess the current status of knowledge, research endeavours and developmental trajectories about proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in correlation with atherosclerosis treatment. Additionally, this study aims to compile bibliometric and scientometric investigations within this domain through rigorous scientometric analysis. Analysing the bibliometric landscape and global research trends associated with PCSK9 inhibitors can contribute valuable insights into comprehending atherosclerosis. This is exemplified by examining publications within the Web of Science Core Collection (WOSCC) database from 2008 to 2022. Citespace was used for frequency, co-occurrence, co-citation, grouping and burst analysis, and Microsoft Excel was used to manage descriptive datasets. Eight hundred eighty-five publications available from WOSCC database between the years 2008 and 2022 were extracted and examined. Over the period, 3,138 collaborating institutions from 87 countries, a staggering 7,750 writers involved and 325 distinct journals published about PCSK9 inhibitors studies. Among authors, Sabatine et al. and the journal The New England Journal of Medicine has had the most significant impact. Lipid-lowering therapy and bempedoic acid are the most prominent topical clusters associated with PCSK9 inhibitors, and the most often used keywords are efficacy, safety and PCSK9 inhibitors. We believe this is the first comprehensive analysis of PCSK9 inhibitors research and publications conducted using Scientometric. These results demonstrate the nascence of PCSK9 inhibitors research. They may encourage a wide range of stakeholders, particularly early career researchers from various disciplines, to work together in the future.
    Keywords:  PCSK9; PCSK9 inhibitors; atherosclerosis; bempedoic acid; lipid-lowering therapy
    DOI:  https://doi.org/10.21315/mjms2024.31.4.2
  50. J Am Nutr Assoc. 2024 Sep 10. 1-13
    Visual Analysis of Hot Topics and Trends in Nutrition for Decompensated Cirrhosis Between 1994 and 2024.
    Lu Li, Shiyan Wu, Yuping Cao, Yumei He, Xiaoping Wu, Heng Xi, Liping Wu.
       OBJECTIVE: An updated summary of the research profile of nutrition for the last 30 years for decompensated cirrhosis is lacking. This study aimed to explore the literature on nutrition for decompensated cirrhosis, draw a visual network map to investigate the research trends, and provide suggestions for future research. The Web of Science database retrieves the literature on nutrition for decompensated cirrhosis between 1994 and 2024.
    METHODS: We used the cooperative, co-occurrence, and co-citation networks in the CiteSpace knowledge graph analysis tool to explore and visualize the relevant countries, institutions, authors, co-cited journals, keywords, and co-cited references.
    RESULTS: We identified 741 articles on nutrition for decompensated cirrhosis. The number of publications and research interests has generally increased. The USA contributed the largest number of publications and had the highest centrality. The University of London ranked first in the number of articles issued, followed by the University of Alberta and Mayo Clinic. TANDON P, a "core strength" researcher, is a central hub in the collaborative network. Of the cited journals, HEPATOLOGY had the highest output (540, 15.3%).
    CONCLUSIONS: Over the past three decades, the focus of research on nutrition in decompensated cirrhosis has shifted from "hepatic encephalopathy, intestinal failure, metabolic syndrome, and alcoholic hepatitis" to "sarcopenia and nutritional assessment." In the future, nutritional interventions for sarcopenia should be based on a multimodal approach to address various causative factors. Its targeted treatment is an emerging area that warrants further in-depth research.
    Keywords:  Decompensated cirrhosis; nutritional assessment; sarcopenia
    DOI:  https://doi.org/10.1080/27697061.2024.2401608
  51. Risk Anal. 2024 Sep 11.
    The development of resilience research in critical infrastructure systems: A bibliometric perspective.
    Feng Wang, Jin Tian, Zhengguo Xu.
      Critical infrastructure systems (CISs) are the cornerstone of modern cities. Substantial economic losses and social impacts are caused once natural disasters or man-made disruptions attack the CISs. As a "resilient city" has become an essential theme of communities' sustainable development, research on resilience and its practice in industries boost the CISs' capacity to respond and adapt to changing environments. From the Web of Science (WOS) Core Collection, this study screened 1,247 scientific articles related to resilience in CISs and conducted a bibliometric analysis to investigate the evolution and future potential in this field. Topic visualized networks were constructed for CIS resilience using CiteSpace, a dedicated tool for visualizing and analyzing trends and patterns in scientific literature. The results demonstrate collaborative research networks among countries, institutions, main scholar/group networks, and leading journals publishing CIS resilience work. This study also explained how the research interest evolved over the last 20 years and found the current frontiers pointing to "power systems resilience" and "supply chain resilience." The reasons were discussed subsequently from the perspectives of the influence that natural hazards (based on the EM-DAT data) and government policies have upon CISs' resilience work.
    Keywords:  CiteSpace; EM‐DAT database; critical infrastructure systems (CISs); natural hazards; policies; resilience; science mapping
    DOI:  https://doi.org/10.1111/risa.17648
  52. J Ethnopharmacol. 2024 Sep 04. pii: S0378-8741(24)01084-5. [Epub ahead of print]337(Pt 1): 118785
    Emerging insights into traditional Chinese medicine associated with neurodegenerative diseases: A bibliometric analysis.
    Yijie Luo, Boqi Hu, Zhenjun Yuan, Houjia Bi, Jiaqi Yu, Qian Pan.
       ETHNOPHARMACOLOGICAL RELEVANCE: Research suggests that traditional Chinese medicine (TCM) holds promise in offering innovative approaches to tackle neurodegenerative disorders. In our endeavor, we conducted a comprehensive bibliometric analysis to delve into the landscape of TCM research within the realm of neurodegenerative diseases, aiming to uncover the present scenario, breadth, and trends in this field. This analysis presents potentially valuable insights for the clinical application of traditional Chinese medicine and provides compelling evidence supporting its efficacy in the treatment of neurodegenerative conditions.
    AIM OF THE STUDY: The incidence of neurodegenerative diseases is on the rise, yet effective treatments are still lacking. Research indicates that TCM could offer novel perspectives for addressing neurodegenerative conditions. Nonetheless, the literature on this topic is intricate and multifaceted, with existing reviews offering only limited coverage. To gain a thorough understanding of TCM research in neurodegenerative diseases, we undertook a bibliometric analysis to explore the current status, scope, and trends in this area.
    MATERIALS AND METHODS: A literature search was carried out on April 1, 2024, utilizing the Web of Science Core Collection (WoSCC). Visualization and quantitative analyses were then performed with the assistance of CiteSpace, VOSviewer, and R software.
    RESULTS: A total of 6856 articles were retrieved in the search. Research on TCM for neurodegenerative diseases commenced in 1989 and has exhibited a notable overall growth since then. Main research contributors include East Asian countries like China, as well as the United States. Through our analysis, we identified 15 highly productive authors, 10 top-tier journals, 13 citation clusters, 11 influential articles, and observed a progression in keyword evolution across 4 distinct categories. In 2020, there was a significant upsurge in the knowledge base, collaboration efforts, and publication output within the field. This field is interdisciplinary: network pharmacology emerges as the cutting-edge paradigm in TCM research, while Alzheimer's disease remains a prominent focus among neurodegenerative conditions due to its evolving etiology. A burst detection analysis unveils that in 2024, the focal points of research convergence between TCM and neurodegenerative diseases lie in two key biological processes or mechanisms: autophagy and microbiota.
    CONCLUSIONS: For the first time, this study quantitatively and visually captures the evolution of TCM in addressing neurodegenerative diseases, showcasing a notable acceleration in recent years. Our findings underscore the pivotal role of interdisciplinary collaboration and the necessity for increased global partnerships. Network pharmacology, leveraging the advancements of the big data era, embraces a holistic and systematic approach as a novel paradigm in exploring traditional Chinese medicine and unraveling their fundamental mechanisms. Three ethnomedical plants-Tianma, Renshen, and Wuweizi-demonstrate the promise of their bioactive compounds in treating neurodegenerative disorders, bolstered by their extensive historical usage for such ailments. Moreover, our intricate analysis of the evolutionary trajectories of key themes such as targets and biomarkers substantially enriches our comprehension of the underlying mechanisms involved.
    Keywords:  Alzheimer's disease(5); Amyloid beta (aβ) (PubChem CID: 57339250); Aucubin (AUC) (PubChem CID: 91458); Baicalin (PubChem CID: 64982); Bilobalide (PubChem CID: 73581); Gastrodin (PubChem CID: 115067); Ginkgolides (PubChem CID: 11973122); Ginsenoside Rg1 (PubChem CID: 441923); Gintonin (PubChem CID: 44559009); Network pharmacology(4); Neurodegenerative disease(2); Traditional Chinese medicine(1); autophagy(6); bibliometrics(3)
    DOI:  https://doi.org/10.1016/j.jep.2024.118785
  53. J Health Popul Nutr. 2024 Sep 09. 43(1): 142
    Research status and frontiers of renal denervation for hypertension: a bibliometric analysis from 2004 to 2023.
    Jiaran Li, Xiaohan Zhang, Yuchen Jiang, Huan Wang, Xiongyi Gao, Yuanhui Hu, Bai Du.
       BACKGROUND: Renal Denervation (RDN) is a novel non-pharmacological technique to treat hypertension. This technique lowers blood pressure by blocking the sympathetic nerve fibers around the renal artery, then causing a decrease in system sympathetic nerve excitability. This study aimed to visualize and analyze research hotspots and development trends in the field of RDN for hypertension through bibliometric analysis.
    METHODS: In total, 1479 studies were retrieved on the Web of Science Core Collection (WoSCC) database from 2004 to 2023. Using CiteSpace (6.2.R4) and VOSviewer (1.6.18), visualization maps were generated by relevant literature in the field of RDN for hypertension to demonstrate the research status and frontiers.
    RESULTS: The number of publications was found to be generally increasing. Europe and the United States were the first countries to carry out research on different techniques and related RDN clinical trials. The efficacy and safety of RDN have been repeatedly verified and gained increasing attention. The study involves multiple disciplines, including the cardiovascular system, peripheral vascular disease, and physiological pathology, among others. Research hotspots focus on elucidating the mechanism of RDN in the treatment of hypertension and the advantages of RDN in appliance therapy. Additionally, the research frontiers include improvement of RDN instruments and techniques, as well as exploration of the therapeutic effects of RDN in diseases with increased sympathetic nerve activity.
    CONCLUSION: The research hotspots and frontiers reflect the status and development trend of RDN in hypertension. In the future, it is necessary to strengthen international collaboration and cooperation, conduct long-term clinical studies with a large sample size, and continuously improve RDN technology and devices. These measures will provide new options for more patients with hypertension, thereby improving their quality of life.
    Keywords:  CiteSpace; Hypertension; Knowledge mapping; Renal denervation; VOSviewer
    DOI:  https://doi.org/10.1186/s41043-024-00626-z
  54. Heliyon. 2024 Sep 15. 10(17): e36701
    Global trends and hotpots in standardised patients research in the last 30 years: A bibliometric analysis.
    Beilei Lin, Yujia Jin, Yunjing Qiu, Jing Chen, Zhiguang Ping, Lanlan Zhang.
       Background: The research trends regarding standardised patients(SPs) in the education of health professions students have not been systematically studied.
    Methods: All published literature on SPs from January 1994 to January 2024 in Web of Science was screened by two reviewers. Bibliometric analysis and knowledge mapping visualisation analysis were performed using Cite Space software. The country, institution, journal, keyword co-occurrence, and keyword emergence were visualised.
    Result: A total of 3259 records were analysed. The amount of relevant literature in the past 30 years showed an upward trend involving 109 disciplinary categories, with the United States dominating. The five central research teams were from the United States and Canada. Nursing education is increasingly using SPs, especially in advanced nursing practice. As for the hotspot and trend analysis, the results indicate that there is still continuous attention to the impact of applying standardised patients on improving the communication ability, competence and performance of medical students. Additionally, there is a growing interest in exploring the application of visual simulation or artificial intelligence in standardised patient-related research.
    Conclusions: Research on SPs' has received continued attention. To cater to the diverse requirements of education and clinical context, there is a need for further exploration of SPs utilisation. AI-relevant SPs might be a new alternative for various scenarios in the future.
    Keywords:  Bibliometric analysis; Medical education; Nursing; Standardized patients
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e36701
  55. Spinal Cord. 2024 Sep 09.
    Bibliometric analysis of research on spinal cord and sacral neuromodulation in spinal cord injury.
    Jishi Ye, Jingli Chen, Juan Wang, Juan Ren, Yifan Jia, Zhongyuan Xia.
       STUDY DESIGN: Qualitative studies.
    OBJECTIVES: Spinal cord injury (SCI) is one of the most devastating injuries to the central nervous system that places a major burden on society. Neuromodulation technology involving spinal cord stimulation (SCS) and sacral nerve modulation (SNM) is a promising technique for patients with SCI. However, there has been no bibliometric analysis of research in this field to date.
    SETTING: Not applicable.
    METHODS: Systematic analyses of countries, institutions, authors, journals, co-cited documents, keywords, genes and diseases were performed. Related gene and disease data from the citexs platform were also reviewed. A total of 7437 articles on SCS and SNM in SCI were retrieved from the Web of Science database. The search time was limited to 1985-01-01 to 2022-12-31.
    RESULTS: We identified a significant increase in research output on SCS and SNM in SCI in recent years, with a concentrated period of high publication activity. Multiple publications were identified on neuropathic pain, electronic stimulation, TNF, BDNF and STAT3 gene expression, indicating that complications and potential therapeutic strategies for SCI are a key focus in the field.
    CONCLUSION: Our study provides insights that may help to advance scientific research and potentially improve outcomes in patients with SCI.
    DOI:  https://doi.org/10.1038/s41393-024-01029-x
  56. Toxicol Rep. 2024 Dec;13 101713
    Bibliometric analysis of beneficial cannabis research: Performance analysis and science mapping from 2012 to 2022 and focus on Morocco.
    Fatima-Zahrae Laaboudi, Mohamed Rejdali, Amin Salhi, Abedellah Elyoussfi, Abdelmonaem Talhaoui, Hassan Amhamdi, M'hamed Ahari.
      Beneficial cannabis use has sparked growing interest among researchers, leading to an increase in empirical studies exploring its phytochemistry and applications. However, understanding the overall research orientation remains limited. This study aims to bridge this gap by conducting a bibliometric analysis of 7841 documents published from 2012 to 2022. The analysis reveals an annual growth rate of 16.83 %, with a focus on medicine, pharmacology, toxicology, pharmaceutics, biochemistry, genetics, molecular biology, and neuroscience. Performance analysis highlights metrics of sources, countries, affiliations, and authors, while science mapping identifies keywords, thematic evolution, and citation/co-authorship patterns. Notably, Morocco, despite its limited initial contributions, has shown recent steady growth in cannabis research, with an annual growth rate of 14.31 % and a 51.72 % international collaborative rate. This study provides valuable insights into established fields and potential research directions in cannabis research, paving the way for a deeper understanding among the audience. With the changing legal status of cannabis, research is rapidly expanding, focusing on the plant's bioactive compounds, pharmacological properties, and therapeutic applications. The dominant subject areas are medicine, pharmacology, toxicology, pharmaceutics, biochemistry, genetics, molecular biology, and neuroscience, covering nearly 76 % of the studied papers. Despite limited initial contributions from African countries like Morocco due to legal restrictions, beneficial cannabis research is gaining interest. Future research should prioritize in-depth exploration of specific compounds, comparative studies of cannabis-based products, and rigorous clinical trials. Fostering international collaborations and bridging the gap between research and policymakers are crucial for harnessing the full potential of cannabis while mitigating potential risks. This study serves as a reference for researchers to identify current orientations, blind areas, and gaps in cannabis research, offering suggestions for future studies.
    Keywords:  Bibliometric analysis; Bioactive cannabis; Cannabis; Medical marijuana; Performance analysis; Science mapping
    DOI:  https://doi.org/10.1016/j.toxrep.2024.101713
  57. J Assist Reprod Genet. 2024 Sep 12.
    Unlocking the potential of artificial intelligence in reproductive medicine: a bibliometric analysis from 1999 to 2024.
    Yi Wang, Yanggang Hong.
      
    DOI:  https://doi.org/10.1007/s10815-024-03251-1
  58. J Craniofac Surg. 2024 Sep 12.
    Journal Metrics of the Journal of Craniofacial Surgery: An Analysis Based on the Journal Citation Report 2024.
    Mustafa Said Tekin, Yusuf M Durna, İlhan Bahşi.
       OBJECTIVES: This study aims the analysis of the journal metrics of Journal of Craniofacial Surgery based on 2024 Journal Citation Reports (JCR) data.
    METHODS: In the Journal Citation Reports 2024, shared by Clarivate Analytics on June 20, 2024, the journal metrics of the Journal of Craniofacial Surgery were examined in detail.
    RESULTS: According to the reports published by Clarivate Analytics in 2024, the journal's impact factor in 2023 was determined as 1.0 and the impact factor excluding self-citations was calculated as 0.8. These values show that the impact factor of the journal has increased in recent years. Also, it is seen that the Journal of Craniofacial Surgery, which has been in the fourth quartile (Q4) among the journals in the "Surgery" category for the last 10 years, has risen to the third quartile (Q3) this year.
    CONCLUSIONS: The increase in the impact factor and ranking of the Journal of Craniofacial Surgery shows that the journal has strengthened its position in the scientific field and is moving toward higher levels. However, it is suggested that other metrics should be taken into consideration in addition to the impact factor.
    DOI:  https://doi.org/10.1097/SCS.0000000000010633
  59. Actas Dermosifiliogr. 2024 Sep 09. pii: S0001-7310(24)00711-7. [Epub ahead of print]
    Bibliometric study of the advances made in clinical dermatological research in Spain from 2015 through 2021: update of the MaIND project and interactive online map.
    A Ayén-Rodríguez, M Sánchez-Díaz, M Grau-Pérez, I García-Doval, M Á Descalzo.
       INTRODUCTION: A clinical dermatological research was conducted in Spain from 2005 through 2014 as part of the MaIND project with the provinces or centers with the highest number of published articles. However, a low level of evidence in scientific production was confirmed as the overall result. The aim of this study is to update the Spanish clinical dermatological research in bibliometric terms from 2015 through 2021 with comparisons between both periods of time.
    MATERIAL AND METHODS: We conducted a bibliometric study to replicate the methodology used in the article to be updated. We included articles whose corresponding authors' affiliation was a Spanish dermatological center, which met the criteria for clinical research in dermatology, including a level of evidence ≤ 4.
    RESULTS: A total of 1674 out of the 10199 articles met the inclusion criteria. An interactive map representing quantitative and qualitative indicators calculated for the 2005-2021 is presented here. In the study period, we found an increasing trend both in the number of published articles (p < 0.002) and in the mean number of citation-years per article (p < 0.01). A total of 22 of the articles had a level of evidence > 4, with a positive trend towards more articles having a higher level of evidence (p < 0.03). Actas Dermosifilográficas still maintains its position as the journal with the highest number of articles received (18%, a total of 302 articles).
    CONCLUSIONS: The results of this study show that, in Spain, the scientific production of dermatology represents an upward trend in quantity, impact, and level of evidence.
    Keywords:  Bibliometrics; Bibliometría; Biomedical Research; Clinical research; Dermatología Española; Evidence-based Medicine; Evidencia científica; Investigación biomédica; Investigación clínica; Medicina basada en la evidencia; Scientific evidence; Spanish dermatology
    DOI:  https://doi.org/10.1016/j.ad.2024.09.012
  60. Asian J Surg. 2024 Sep 12. pii: S1015-9584(24)01909-2. [Epub ahead of print]
    Research on ovarian cancer stem cells based on bibliometric analysis.
    Mei Liu, Lu Zhou, Huili Zhu.
      
    Keywords:  Bibliometrics analysis; CiteSpace; Ovarian cancer; Tumor stem cells; VOSviewer
    DOI:  https://doi.org/10.1016/j.asjsur.2024.08.168
  61. Can J Microbiol. 2024 Sep 10.
    Tracking the trajectory of frankia research through bibliometrics: Trends and future directions.
    Ridha Mhamdi, Maher Gtari.
      Frankia represent a unique group of filamentous, sporangia-forming bacteria, renowned for their exceptional capacity to establish symbiotic partnerships with actinorhizal plants. The objective of this paper is to offer quantitative insights into the current state of frankia research and its future potential. A comprehensive bibliometric analysis of two decades (2000-2022) was conducted using Scopus and SciVal. A steady increase in annual publication and international collaboration was observed, particularly since 2013. Research performance metrics for the last five years (2018-2022) indicate China and India as leaders with high FWCI scores. This analysis highlighted prominent authors, research groups, and the evolving research landscape, suggesting an increasing focus on molecular and genomic aspects. The genomic era has transformed our understanding of frankia biology, highlighting their significance in diverse ecological and agricultural contexts. This study comprehensively maps the evolving landscape of frankia research, emphasizing key milestones that have catalysed international interest in frankia-actinorhizal research, expanding our perception of frankia's capabilities beyond its traditional symbiotic role. As research in this field progresses, a deeper comprehension of frankia-plant interactions, symbiotic signalling, and the intricacies of metabolic pathways holds the promise of revealing innovative techniques for optimizing nitrogen fixation and broadening the spectrum of host plants.
    DOI:  https://doi.org/10.1139/cjm-2024-0030
  62. Int J Radiat Oncol Biol Phys. 2024 Oct 01. pii: S0360-3016(24)03150-X. [Epub ahead of print]120(2): 306-308
    The Top 20 Cited and Downloaded Red Journal Articles of 2023.
    Sue S Yom.
      
    DOI:  https://doi.org/10.1016/j.ijrobp.2024.08.001
  63. J Clin Nurs. 2024 Sep 11.
    Bibliometric Analyses: Do They Contribute to Knowledge?
    Roger Watson, Mark Hayter.
      
    DOI:  https://doi.org/10.1111/jocn.17423
  64. Healthcare (Basel). 2024 Aug 30. pii: 1733. [Epub ahead of print]12(17):
    Assessing Functional Ankle Instability in Sport: A Critical Review and Bibliometric Analysis.
    Élio Alexandre, Diogo Monteiro, Ricardo SottoMayor, Miguel Jacinto, Fernanda M Silva, Luis Cid, Pedro Duarte-Mendes.
      Functional Ankle Instability (FAI) is the subject of extensive research in sports and other environments. Given the importance of accurately measuring this latent construct, it is imperative to carry out a careful assessment of the available tools. In this context, the aim of this review was to take an in-depth look at the six most cited measurement tools to assess FAI, with a specific focus on patient-reported outcome measures related to ankle and foot. Four electronic databases (Web of Science, Scopus, Pubmed, and SportDiscus) were searched (up to November 2022) to identify the six most cited questionnaires for assessing FAI. Our analysis showed that the most cited questionnaires are the following: the Lower Extremity Functional Scale (LEFS), the Foot Function Index (FFI), the Foot and Ankle Ability Measure (FAAM), the Foot and Ankle Outcome Score (FAOS), the Olerud and Molander Ankle Score (OMAS), and the Cumberland Ankle Instability Tool (CAIT). Each questionnaire was thoroughly assessed and discussed in three sections: Development, Reliability, and Summaries. In addition, bibliometric data were calculated to analyze the relevance of each questionnaire. Despite variations in terms of validity and reliability, conceptualization, structure, and usefulness, the six questionnaires proved to be robust from a psychometric point of view, being widely supported in the literature. The bibliometric analyses suggested that the FAOS ranks first and the FFI ranks sixth in the weighted average of the impact factors of their original publications.
    Keywords:  ankle; functional instability; questionnaire
    DOI:  https://doi.org/10.3390/healthcare12171733
  65. Front Pharmacol. 2024 ;15 1466156
    The mechanisms and drug therapies of colorectal cancer and epigenetics: bibliometrics and visualized analysis.
    Siyu Tian, Min Chen.
       Background: Numerous studies have demonstrated a link between epigenetics and CRC. However, there has been no systematic analysis or visualization of relevant publications using bibliometrics.
    Methods: 839 publications obtained from the Web of Science Core (WoSCC) were systematically analyzed using CiteSpace and VOSviewer software.
    Results: The results show that the countries, institutions, and authors with the most published articles are the United States, Harvard University, and Ogino and Shuji, respectively. SEPT9 is a blood test for the early detection of colorectal cancer. Vitamin D and gut microbiota mediate colorectal cancer and epigenetics, and probiotics may reduce colorectal cancer-related symptoms. We summarize the specific epigenetic mechanisms of CRC and the current existence and potential epigenetic drugs associated with these mechanisms. It is closely integrated with clinical practice, and the possible research directions and challenges in the future are proposed.
    Conclusion: This study reviews the current research trends and hotspots in CRC and epigenetics, which can promote the development of this field and provide references for researchers in this field.
    Keywords:  bibliometrics; colorectal cancer; drug therapies; epigenetics; mechanisms
    DOI:  https://doi.org/10.3389/fphar.2024.1466156
  66. Arch Sex Behav. 2024 Sep 13.
    Sexual Affectivity in Autism Spectrum Disorder: Bibliometric Profile of Scientific Production.
    Jordi Torralbas-Ortega, Victòria Valls-Ibáñez, Judith Roca, Carme Campoy-Guerrero, Meritxell Sastre-Rus, Judith García-Expósito.
      The aim of the present study was to describe the scientific production on sexuality and affectivity of autistic people. The inclusion criteria were articles published in all languages from the year 2000 to 2023, excluding reviews, proceedings, and other works not considered original. The search was performed in the Web of Science Core Collection and RStudio was utilized to analyze the records, with the "Bibliometrix 4.1.0" package and the VOSviewer software. A total of 314 articles were included, from the USA, Australia, and parts of Europe. The production peak was found in the year 2020, the most cited articles referred to the children's population, and the most important journals were specialized on the subject. As for the thematic content, 29 keywords emerged that were grouped into three clusters. In the first group, children associated with vulnerability and victimization were underlined, in which multifocal interventions were needed to prevent risk; in the second, we found adolescents and the need for sex education that is adapted and comprehensive; and lastly, adults who must be able to perform an adequate transition that eases the adaptation of neurodivergent individuals.
    Keywords:  Affective symptoms; Autism spectrum disorder; Bibliometrics; Sexual behavior; Sexuality
    DOI:  https://doi.org/10.1007/s10508-024-02996-1
  67. Carbohydr Polym. 2024 Dec 15. pii: S0144-8617(24)00845-2. [Epub ahead of print]346 122619
    Advances in agar-based composites: A comprehensive review.
    Muffarih Shah, Abdul Hameed, Muhammad Kashif, Noor Majeed, Javariya Muhammad, Nasrullah Shah, Touseef Rehan, Abbas Khan, Jalal Uddin, Ajmal Khan, Hamdy Kashtoh.
      This review article explores the developments and applications in agar-based composites (ABCs), emphasizing various constituents such as metals, clay/ceramic, graphene, and polymers across diversified fields like wastewater treatment, drug delivery, food packaging, the energy sector, biomedical engineering, bioplastics, agriculture, and cosmetics. The focus is on agar as a sustainable and versatile biodegradable polysaccharide, highlighting research that has advanced the technology of ABCs. A bibliometric analysis is conducted using the Web of Science database, covering publications from January 2020 to March 2024, processed through VOSviewer Software Version 1.6.2. This analysis assesses evolving trends and scopes in the literature, visualizing co-words and themes that underscore the growing importance and potential of ABCs in various applications. This review paper contributes by showcasing the existing state-of-the-art knowledge and motivating further development in this promising field.
    Keywords:  Agar; Agar-based composites; Bibliometric analysis; Biomedical engineering; Food packaging; Waste water treatment
    DOI:  https://doi.org/10.1016/j.carbpol.2024.122619
  68. World Neurosurg. 2024 Sep 11. pii: S1878-8750(24)01571-7. [Epub ahead of print]
    Exploring the evolution of research connectivity and funding in global neurosurgical publications.
    Andreas Seas, Liming Qiu, Emma Paradie, Jasmine Hughes, Pranav I Warman, Romaric Waguia-Kouam, Nathan A Shlobin, Kennedy Carpenter, Megan von Isenburg, Michael M Haglund, Anthony T Fuller, Alvan-Emeka K Ukachukwu.
       BACKGROUND AND OBJECTIVES: There are critical disparities in the neurosurgical care provided around the globe due to challenges in resource allocation, training, and infrastructure. Global neurosurgical collaborations have replaced classical mission trips to address these disparities. However, the development of these collaborations and the impact of research funding on their growth has not yet been systematically studied. In this article, we use a graph theoretical approach to investigate trends in funding and co-authorship between and among authors from high-income countries (HICs) and authors from low- and middle-income countries (LMICs).
    METHODS: A bibliometric search of the global neurosurgical literature returned 307 articles between 1985 and 2020. A connectivity analysis was conducted to compute the number of co-authorships between HIC-HIC, LMIC-HIC, and LMIC-LMIC authors. The number of connections, summarized as either a global sum of connections or an average number of connections per manuscript, were analyzed in the context of time and funding through parametric statistical tests.
    RESULTS: An exponential increase in co-authorship collaboration was observed over time, especially after 2015. Notably, LMIC-LMIC collaborations appear to be rising at over twice the rate of other collaboration types. The presence of funding, in general, was associated with increased co-authorship of manuscripts by LMIC and HIC authors together (p = 0.033). A significant majority of the funding associated with LMIC-HIC co-authorships was supplied through charitable organizations and government grants (p = 0.034, p = 0.009, respectively). Most LMIC-LMIC co-authorships had no funding.
    CONCLUSION: This work shows significant and rapid growth in international neurosurgical partnerships, especially in HIC-LMIC and LMIC-LMIC collaborations. Also, a significant positive relationship exists between research funding and LMIC-HIC co-authorship trends. This work encourages us as a community to continue to expand our translational collaborations with LMIC neurosurgeons and establish funding mechanisms independent of HIC authors.
    Keywords:  Collaborations; Connectivity; Funding; Global Health Research; Global Neurosurgery; Networks
    DOI:  https://doi.org/10.1016/j.wneu.2024.09.029
  69. IEEE Trans Vis Comput Graph. 2024 Sep 10. PP
    PUREsuggest: Citation-based Literature Search and Visual Exploration with Keyword-controlled Rankings.
    Fabian Beck.
      Citations allow quickly identifying related research. If multiple publications are selected as seeds, specifc suggestions for related literature can be made based on the number of incoming and outgoing citation links to this selection. Interactively adding recommended publications to the selection refnes the next suggestion and incrementally builds a relevant collection of publications. Following this approach, the paper presents a search and foraging approach, PUREsuggest, which combines citation-based suggestions with augmented visualizations of the citation network. The focus and novelty of the approach is, frst, the transparency of how the rankings are explained visually and, second, that the process can be steered through user-defned keywords, which refect topics of interests. The system can be used to build new literature collections, to update and assess existing ones, as well as to use the collected literature for identifying relevant experts in the feld. We evaluated the recommendation approach through simulated sessions and performed a user study investigating search strategies and usage patterns supported by the interface.
    DOI:  https://doi.org/10.1109/TVCG.2024.3456199
  70. Heliyon. 2024 Aug 30. 10(16): e36578
    A bibliometric analysis of IoT applications in logistics and supply chain management.
    Imen Zrelli, Abderahman Rejeb.
      The rapid integration of the Internet of Things (IoT) into logistics and supply chain management (SCM) marks a significant transformation towards enhanced efficiencies, security, and sustainability. Through a comprehensive bibliometric analysis of 2680 publications from the Scopus database, this study charts the evolution of IoT within logistics and SCM and reveals a shift from foundational explorations to mature implementations. The research unfolds a complex thematic structure, highlighting the revolutionary impacts of IoT and related technologies such as RFID, the synergy of Industry 4.0 with SCM through Artificial Intelligence (AI) and the Industrial Internet of Things (IIoT), the strategic role of blockchain for enhanced traceability and security, and the advent of novel communication and encryption technologies for secure data exchanges. Further, the analysis categorizes the scholarly discourse into critical areas including big data and IoT optimization in SCM, IoT-driven innovation in the food supply chain, applications of blockchain and smart contracts, digital transformation through Industry 4.0, security advancements with intelligent systems, and the exploration of advanced technologies for Industry 4.0 and 5.0. This review not only delineates the intellectual landscape of IoT applications in logistics and SCM but also identifies emerging research areas such as blockchain integration, 5G potential, and AI-driven optimizations, suggesting pathways for future research to broaden the understanding in this dynamically evolving field. It serves as an essential resource for academics and practitioners, providing insights into the transformative role of IoT in logistics and SCM and proposing directions for future technological and academic endeavors.
    Keywords:  Bibliometrics; Industry 4.0; Internet of things; Logistics; Supply chain management
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e36578
  71. Heliyon. 2024 Aug 30. 10(16): e35946
    The emerging field of Robo Advisor: A relational analysis.
    Mar Arenas-Parra, Héctor Rico-Pérez, Raquel Quiroga-Garcia.
      Robo advising is an emerging business model that aims to popularize investment advisory services by automating all the activities involved. The robo-advisor (RA) stream of research is relatively new, yet it has started to attract the attention of numerous scholars. This manuscript aims to analyze the academic literature on RA based on its impact on the different phases that make up the investment advice process. Our aim is to investigate which phases of the investment advice service prove of most interest to scholars. Since selecting relevant and precise keywords increases the visibility, accessibility, and indexing of a research paper, we explore the RA research landscape using keyword relational analysis. We analyze metadata from 195 identified papers combining the Scopus and Web of Science databases until May 2022. The analysis unfolds in two parts. First, we examine the relationships and associations of keywords in titles, abstracts, and author keywords to extract knowledge patterns from said associations. As a novelty, a specific dictionary of RA-synonyms formed by 19 disjoint families of concepts is obtained. The second part presents the RA's conceptual and relational structure. For this, five clusters are determined to identify and organize those studies dealing with similar topics. The results of our study suggest that research is more interested in aspects related to the human factor, namely, those with phases requiring more direct contact with the client or investor. The most relevant research interests include the automation of client profiling functions and client response to the latter automation.
    Keywords:  Investment advice service; Relational analysis; Robo Advisor
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35946
  72. Heliyon. 2024 Aug 30. 10(16): e36375
    Current research status and emerging trends in wheat: An integrated scientometric analysis based on ploidy uncovers hidden footprints in the scientific landscape.
    Tilak Chandra, Jagajjit Sahu, Sarika Jaiswal, Mir Asif Iquebal, Dinesh Kumar.
      Wheat, a highly versatile staple crop cultivated extensively for its grains on a global scale, is poised to experience increased demand to sustain the burgeoning population, owing to its superior nutritional potential. Modern wheat, a hexaploid species, has evolved through the introgression of numerous preceding ploidies, including Einkorn, Emmer, Aegilops, and others, each possessing distinct qualitative and quantitative traits. Scientometric and topical analyses serve as effective tools to quantitatively evaluate scientific research by measuring the knowledge expressed in scientific publications and keywords. Thus, comprehending the research status regarding wheat domestication events within primary, secondary, and tertiary gene pools is paramount for enhancing wheat production. In this study, we analyze data retrieved from PubMed to elucidate the research status and identify bottlenecks across different ploidy of genomic pools of wheat. The publication trends on wheat have experienced exponential growth over the past three decades, with China emerging as a leading center for publications. In contrast to the publication frequency observed in hexaploid common wheat, scholarly output concerning Einkorn and Aegilops is approximately tenfold lesser, with emmer trailing behind at three times fewer publications. This discrepancy underscores the prioritization of expedited research initiatives targeting these species, aimed at elucidating latent biological characteristics and optimizing their breeding capabilities. Keywords such as "stress," "GWAS," and "gene" are prominent, reflecting the challenges posed by climatic factors on wheat production and their mitigation through molecular breeding and gene manipulation. Notably, the keyword "einkorn" highlights its potential as a donor for fine-tuning traits related to wheat adaptation processes and quality, crucial for modern wheat's survivability under adverse climates. Conversely, higher publication rates on emmer are primarily associated with Italy, possibly due to its favorable Mediterranean climate for tetraploid wheat. Keywords like "Pasta" and "Ochratoxin, DON" are prevalent, with the former being derived from durum wheat and the latter being reported in higher amounts in durum compared to other wheat species, rendering it less suitable for consumption. Enriched keywords such as "genome" and "resistance" underscore the critical characteristics of Aegilops. Other significant keywords like "Aceria tosichella" possibly indicate multiple stages of resistance conferred by Aegilops, while the presence of the grain softness protein "puroindoline" enhances its acceptability for donation by Aegilops. Spelt, a close relative of common wheat, exhibits a research trend with thousands of annual publications and enriched keywords such as "stress" and "yield" reflect the current scientific emphasis on wheat research. Furthermore, hierarchical keywords like "bio-control" and "celiac disease" merit consideration for future research on hexaploid wheat.
    Keywords:  China; Natural language processing; Polyploidy; PubMed; Scientometrics; Topical analysis; Wheat
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e36375
  73. Waste Manag Res. 2024 Sep 10. 734242X241270930
    A bibliometric review of waste management and innovation: Unveiling trends, knowledge structure and emerging research fronts.
    Ana Maria Ortega Alvarez, Karolína Malá, Maribel Serna Rodriguez.
      The pressing challenges in waste management have motivated this comprehensive study examining prior research and contemporary trends concerning innovation and waste management. A meticulous investigation of 2264 documents (1968-2024) was conducted using bibliometrix R-tool to analyse Scopus and Web of Science databases, offering a holistic global perspective. Heightened societal concern about waste management, driven by soaring waste production from consumption patterns, requires urgent exploration of effective waste elimination and transformation systems. This study provides a comprehensive summary of the topic, delving deeply into its complexities. Through thorough analysis of global trends, it constitutes a significant stride towards identifying effective solutions, offering valuable contributions to both scientific understanding and practical applications. This research pioneers a comprehensive synthesis of innovation and waste management issues, showcasing originality and substantial contributions. The identified collaborative networks expose a lack of transnational cooperation, potentially hindering waste management innovation. Future research around waste management innovation should focus on synergies among competitors within the same industry and across industries to minimize waste and maximize resource utilization, 4.0 technologies, global waste chain impacts and challenges along with solutions for developing countries.
    Keywords:  JEL codes; Scopus; Waste management; Web of Science; bibliometrix R-Tool; innovation; literature review; network analysis
    DOI:  https://doi.org/10.1177/0734242X241270930
  74. An Acad Bras Cienc. 2024 Sep 06. pii: S0001-37652024000500101. [Epub ahead of print]96(3): e2024963
    A brief assessment of the influence of Animal Science in the Impact Factor of the AABC.
    Alexander W A Kellner.
      
    DOI:  https://doi.org/10.1590/0001-376520242024963
  75. Medicine (Baltimore). 2024 Sep 06. 103(36): e39334
    Intersecting evidence: Bibliometric analysis and clinical trials illuminate immunotherapy in KRAS-mutation cancer: A review.
    Hongyang Liu, Min Qiang, Ying Zhang, Hong Wang, Yang Xing, Rui Guo.
      KRAS mutations play a critical role in the development and progression of several cancers, including non-small cell lung cancer and pancreatic cancer. Despite advancements in targeted therapies, the management of KRAS-mutant tumors remains challenging. This study leverages bibliometric analysis and a comprehensive review of clinical trials to identify emerging immunotherapies and potential treatments for KRAS-related cancers. Using the Web of Science Core Collection and Citespace, we analyzed publications from January 2008 to March 2023 alongside 52 clinical trials from ClinicalTrials.gov and WHO's registry, concentrating on immune checkpoint blockades (ICBs) and novel therapies. Our study highlights an increased focus on the tumor immune microenvironment and precision therapy. Clinical trials reveal the effectiveness of ICBs and the promising potential of T-cell receptor T-cell therapy and vaccines in treating KRAS-mutant cancers. ICBs, particularly in combination therapies, stand out in managing KRAS-mutant tumors. Identifying the tumor microenvironment and gene co-mutation profiles as key research areas, our findings advocate for multidisciplinary approaches to advance personalized cancer treatment. Future research should integrate genetic, immunological, and computational studies to unveil new therapeutic targets and refine treatment strategies for KRAS-mutant cancers.
    DOI:  https://doi.org/10.1097/MD.0000000000039334
  76. J Craniofac Surg. 2024 Sep 12.
    Content Analysis of the Top 25 Most Cited Articles of the Journal of Craniofacial Surgery With ChatGPT-4o.
    Yusuf Muhammed Durna, Mustafa Said Teki N, Yaşar Kemal Duymaz, Ahmet Mahmut Teki N, İlhan Bahşi.
       OBJECTIVE: Since 1990, the Journal of Craniofacial Surgery has been an important resource for clinicians and basic scientists. The journal addresses clinical practice, surgical innovations, and educational issues. This study aims to evaluate the contribution of these articles to clinical practice innovations and surgical procedures by analyzing the content of the 25 most cited articles published in the journal. It also aims to demonstrate the potential of artificial intelligence tools in academic content analysis.
    METHODS: All articles published in the Journal of Craniofacial Surgery on June 13, 2024, were searched using the Web of Science Database, and the 25 most cited articles were identified. The full texts of these articles were saved in PDF format and metadata were saved as plain text files. Content analysis of these 25 articles was performed using ChatGPT-4o.
    RESULTS: As a result of the analysis, some articles stood out in terms of clinical importance. It also appeared that ChatGPT could be used to compare multiple articles.
    CONCLUSION: In this study, the authors analyzed the content of the 25 most cited articles published in the Journal of Craniofacial Surgery using ChatGPT-4o. These articles were evaluated according to the criteria of innovations in clinical practice and compliance with surgical procedures. This study presents interesting findings in terms of the use of artificial intelligence tools in academic content analysis. The authors thought that this study could be a source of inspiration for future studies.
    DOI:  https://doi.org/10.1097/SCS.0000000000010619
  77. Nat Commun. 2024 Sep 12. 15(1): 7527
    The global geography of artificial intelligence in life science research.
    Leo Schmallenbach, Till W Bärnighausen, Marc J Lerchenmueller.
      Artificial intelligence (AI) promises to transform medicine, but the geographic concentration of AI expertize may hinder its equitable application. We analyze 397,967 AI life science research publications from 2000 to 2022 and 14.5 million associated citations, creating a global atlas that distinguishes productivity (i.e., publications), quality-adjusted productivity (i.e., publications stratified by field-normalized rankings of publishing outlets), and relevance (i.e., citations). While Asia leads in total publications, Northern America and Europe contribute most of the AI research appearing in high-ranking outlets, generating up to 50% more citations than other regions. At the global level, international collaborations produce more impactful research, but have stagnated relative to national research efforts. Our findings suggest that greater integration of global expertize could help AI deliver on its promise and contribute to better global health.
    DOI:  https://doi.org/10.1038/s41467-024-51714-x
  78. Int Wound J. 2024 Sep;21(9): e70036
    The uptake of the international pressure ulcer/injury prevention and treatment guidelines: An updated systematic citation analysis.
    Monira El Genedy-Kalyoncu, Jan Kottner.
      The European Pressure Ulcer Advisory Panel, National Pressure Injury Advisory Panel, and Pan Pacific Pressure Injury Alliance collaboratively developed three editions of the International Clinical Practice Guidelines for preventing and treating pressure ulcers/injuries in 2009, 2014, and 2019. Dissemination and uptake of these guidelines are important to improve care. The aim of this work was to provide an updated and expanded citation analysis of the three published guidelines. Referencing formats, citation counts, and global distribution of citations of the 2009, 2014, and 2019 guidelines were searched in the citation database Scopus from 2009 to 2023. Duplicates were removed manually. The search identified 330 referencing formats with 2887 citations from 2009 to 2023 for the three guideline editions. Citations displayed geographical diversity, with citation peaks observed approximately 4 years after each edition's release and ongoing citations to the present. The International Clinical Practice Guidelines for preventing and treating pressure ulcers/injuries updated since 2009 were cited more than 2800 times in the scientific literature exceeding the thresholds of highly cited papers in the field of clinical medicine. This indicates successful dissemination worldwide.
    Keywords:  information dissemination; practice guideline; pressure injury; pressure ulcer; skin
    DOI:  https://doi.org/10.1111/iwj.70036
  79. Mycology. 2024 ;15(3): 360-373
    Bibliometric, taxonomic, and medicinal perspectives of Ganoderma neo-japonicum Imazeki: A mini review.
    Meng Fei Lau, Chia Wei Phan, Vikineswary Sabaratnam, Umah Rani Kuppusamy.
      Ganoderma, a traditional medicine in Asian countries, has been used to prevent and treat various ailments for centuries. Ganoderma neo-japonicum (synonym Ganoderma bambusicola), also known as purple Lingzhi, is a species that is currently underutilised when compared to Ganoderma lucidum (Lingzhi). However, in recent decades, this mushroom has garnered significant attention due to its ethnomedicinal uses, especially in Southeast Asia regions like Malaysia. The taxonomy and nomenclature of this mushroom have been extensively studied. Numerous publications have reported that G. neo-japonicum displays a variety of medicinal properties, including antioxidation, anticancer, anti-hyperglycaemic, genoprotective, hepatoprotective, neuritogenic, and antidiabetic effects, both in vitro and in vivo. With the surge of research findings on this mushroom, this review aims to provide a systematic bibliometric analysis of G. neo-japonicum, published between 1991 to 2021. Additionally, the taxonomic description of this mushroom is discussed in detail. Our review reveals that G. neo-japonicum contains polysaccharides (α/β-D-glucans), triterpenoids, and sterols/ergosterol. However, the existing literature suggests that these active compounds have not yet been explored to their full potential as drug candidates. Moreover, most of the studies are preclinical and have several drawbacks. In conclusion, G. neo-japonicum possesses valuable pharmacological activities that merit further exploration.
    Keywords:  Ganoderma bambusicola; Ganoderma neo-japonicum; anticancer; bibliometric analysis; domestication; purple reishi; taxonomy
    DOI:  https://doi.org/10.1080/21501203.2024.2302028
  80. Heliyon. 2024 Aug 30. 10(16): e36389
    Multispectral imaging in medicine: A bibliometric study.
    Zexu Lin, Xiheng Hu, Yuancheng Liu, Sicen Lai, Lingjia Hao, Yihao Peng, Yixin Li, Zirui Zhu, Xing Huang, Kai Huang, Mi Zhang.
      Multispectral Imaging has been used in many fields. In the medical field, Multispectral Imaging is still in its infancy. However, due to its excellent potential, it will also become one of the most important medical imaging in the future. This paper is the first bibliometric study in this field. The study comprehensively searched all relevant documents in Web of Science Core Collection from Jan 1, 1999 to Dec 31, 2022, systematically sorted out the author, journal, country and institution in this field, and analyzed the keywords. Based on this, the study suggests that researchers and healthcare workers should strengthen cooperation to apply Multispectral Imaging to more medical fields while further developing related technologies. At the same time, in the future, this field should focus on non-ex vivo tissue detection and the combination of Multispectral Imaging and artificial intelligence.
    Keywords:  Artificial intelligence; Multispectral imaging; Multispectral optoacoustic tomography; Photodynamic therapy
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e36389
  81. Arthroscopy. 2024 Sep 05. pii: S0749-8063(24)00641-8. [Epub ahead of print]
    Editorial Commentary: Experts in Shoulder Surgery Do Not Consistently Detect Artificial Intelligence-Generated Scientific Abstracts.
    Mikalyn T DeFoor, Andrew J Sheean.
      There has been an exponential growth in the number of artificial intelligence (AI) and machine learning (ML)-related publications in recent years. For example, in shoulder and elbow surgery, there was a 6-fold increase in the number of publications between 2018 and 2021. AI shows potential to improve diagnostic precision, generate precise surgical templates, direct personalized treatment plans, and reduce administrative costs. However, while AI and ML technologies have the ability to positively impact biomedical research, it should be closely monitored and used with extreme caution in the realm of research and scientific writing. Of concern, current large language models raise concerns regarding veracity of AI-generated content, copyright and ownership infringement, fabricated references, lack of in-text citation, plagiarism, and questions of authorship. Recent research shows that even the most experienced surgeons are unable to consistently detect AI-generated scientific writing. Of note, AI detection software is more adept in this role. AI should be used with caution in the development and production of scholarly work.
    DOI:  https://doi.org/10.1016/j.arthro.2024.08.038
  82. J Prof Nurs. 2024 Sep-Oct;54:pii: S8755-7223(24)00115-7. [Epub ahead of print]54 194-197
    Publication patterns of graduates from a DNP program with submission of a manuscript as a degree requirement.
    Julee Briscoe Waldrop, Marion E Broome.
       BACKGROUND: Nurses who earn a Doctor of Nursing Practice (DNP) degree are expected to make essential contributions to the scholarship of practice and the improvement of health care outcomes. The DNP program at Duke University School of Nursing requires that students demonstrate scholarship competence by writing a manuscript based on their DNP project and submitting it for publication.
    PURPOSE: The purpose of this article is to share an evaluation of the effectiveness of this approach.
    METHODS: The authors used a bibliometric study design.
    RESULTS: This study demonstrates that manuscripts authored by students based on the DNP projects they conduct while earning their DNP degree can be published and are cited by other scholars. Additionally, the majority of these authors continue to publish scholarly work in the nursing and broader health-focused literature after they graduate.
    CONCLUSION: Nurses who developed and submit manuscripts for publication based on their DNP project contribute to the literature and evidence base for practice.
    Keywords:  Citations; Doctor of nursing practice; Graduate nursing education; Publication; Scholarship; Writing
    DOI:  https://doi.org/10.1016/j.profnurs.2024.06.021
  83. BMJ Evid Based Med. 2024 Sep 12. pii: bmjebm-2024-113033. [Epub ahead of print]
    Do infographics 'spin' the findings of health and medical research?
    Ryan Muller, Giovanni Ferreira, Geronimo Bejarano, Andrew R Gamble, James Kirk, James Sindone, Joshua R Zadro.
       OBJECTIVE: To compare the prevalence of 'spin', and specific reporting strategies for spin, between infographics, abstracts and full texts of randomised controlled trials (RCTs) reporting non-significant findings in the field of health and medicine and to assess factors associated with the presence of spin.
    DESIGN: Cross-sectional observational study.
    DATA SOURCE: Publications in top quintile health and medical journals from August 2018 to October 2020 (Journal Citation Reports database).
    ELIGIBILITY CRITERIA: Infographics, abstracts and full texts of RCTs with non-significant results for a primary outcome.
    MAIN OUTCOMES AND MEASURES: Presence of spin (any spin and spin in the results and conclusions of infographics, abstracts and full texts).
    EXPOSURES: Conflicts of interest, industry sponsorship, trial registration, journal impact factor, spin in the abstract, spin in the full text.
    RESULTS: 119 studies from 40 journals were included. One-third (33%) of infographics contained spin. Infographics were not more likely to contain any spin than abstracts (33% vs 26%, OR 1.4; 95% CI 0.8 to 2.4) or full texts (33% vs 26%, OR 1.4; 95% CI 0.8 to 2.4). Higher journal impact factor was associated with slightly lower odds of spin in infographics and full texts, but not abstracts. Infographics, but not abstracts or full texts, were less likely to contain spin if the trial was prospectively registered. No other significant associations were found.
    CONCLUSIONS: Nearly one-third of infographics spin the findings of RCTs with non-significant results for a primary outcome, but the prevalence of spin is not higher than in abstracts and full texts. Given the increasing popularity of infographics to disseminate research findings, there is an urgent need to improve the reporting of research in infographics.
    Keywords:  Health; Methods; Publishing
    DOI:  https://doi.org/10.1136/bmjebm-2024-113033
  84. Heliyon. 2024 Aug 30. 10(16): e35979
    Behavioral finance in a hundred keywords.
    Teresa Corzo, Ramón Hernán, Guillermo Pedrosa.
      We analyze leading journals in behavioral finance to identify the most-used keywords in the area and how they have evolved. Using keyword analysis of data between 2000 and 2020 as well as data mapping and visualization tools, a dynamic map of the discipline was constructed. This study assesses the state-of-the-art of the field, main topics of discussion, relationships that arise between the concepts discussed, and emerging issues of interest. The sample comprises 3876 pieces, including 15859 keywords from journals responsible for the growth of the discipline, namely the Journal of Behavioral and Experimental Economics, Journal of Behavioral and Experimental Finance, Journal of Economic Psychology, Journal of Behavioral Finance, and Review of Behavioral Finance. During the period analyzed, our results depict a lively area and highlight the prominent role that experiments play in the field. Two related but different streams of behavioral finance research are revealed.
    Keywords:  Behavioral finance; Co-word; Data mapping; Data visualization; Keywords analysis; Top journal
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35979
  85. Int J Sports Physiol Perform. 2024 Sep 13. 1-5
    University Rankings in Sport Science: A True Reflection of Excellence?
    Ivana Matic Girard, Olivier Girard.
       BACKGROUND: University rankings often serve as benchmarks for excellence in academic evaluation. For example, ShanghaiRanking data from 2016 to 2023 for the Global Ranking of Sport Science Schools and Departments reveal consistent dominance by Australia (23.1%), Canada (18.0%), and the United States (12.0%), collectively counting over half of the top 50 universities worldwide. Nevertheless, there is uncertainty about how the methodology behind these rankings shapes a reality as much as it reflects one.
    PURPOSE: Our intention is to discuss the complexity of university rankings, using ShanghaiRanking as an example, to highlight how these rankings reflect academic excellence within the field of sport science. Current Evidence: When ranking universities in sport science, several aspects of academic excellence could be considered in addition to research metrics currently considered in ShanghaiRanking (publication, citation, citations per publication, top 25% journal publications, and internationally collaborated publications). These aspects may include (1) teaching quality, (2) practical training, (3) industry links and employability, (4) support services, (5) facilities and equipment, (6) international network, (7) community engagement, (8) sustainability and ethical practices, and (9) interdisciplinary approach. Altogether, they could provide a more comprehensive view of the quality and effectiveness of a sport-science program.
    CONCLUSIONS: The ranking of sport-science institutions poses a complex challenge due to diverse factors influencing academic excellence. Engaging in a broader dialogue and refining internationally relevant evaluation methodologies are crucial. These steps enable comparability between countries and provide a holistic understanding of the multidimensional nature of academic excellence in sport science.
    Keywords:  academic excellence; evaluation methodologies; research impact
    DOI:  https://doi.org/10.1123/ijspp.2024-0109
  86. J Prosthet Dent. 2024 Sep 05. pii: S0022-3913(24)00557-2. [Epub ahead of print]
    Response to Letter to the Editor regarding, "The application of 3D printing in dentistry: A bibliometric analysis from 2012 to 2023 (J Prosthet Dent. 2024 Jul 1)".
    Guangwei Chen, Jingkun Zhang, Jianfeng He, Yongqi Li, Chengwei Li, Zhiyan Lin, Huilin Wu, Libin Zhou.
      
    DOI:  https://doi.org/10.1016/j.prosdent.2024.07.041
  87. Rev Med Chil. 2023 Dec;pii: S0034-98872023001201604. [Epub ahead of print]151(12): 1604-1612
    [Analysis of Clinical-Scientific Research on Diabetes Mellitus in Chile: A 13-Year Study].
    Astrid Von Oetinger G, Luz María Trujillo G, Nestor Soto I.
       INTRODUCTION: Chile has one of the highest prevalences of Diabetes Mellitus (DM) in Latin America. Therefore, it is relevant to conduct a scientific analysis to identify national scientific productivity in this field objectively and determine if the research efforts are directed toward clinical priorities.
    MATERIALS AND METHODS: A systematic review of research conducted on DM in Chile was designed. Scientific evidence from the years 2010 to 2022 was considered. The scientific search was conducted in four databases (PubMed, EMBASE, Scopus, and Scielo) and guided by the PRISMA statement (Preferred Reporting Items for Systematic Review and Meta-Analysis) executed through the COVIDENCE® platform.
    RESULTS: Out of the 1,953 articles identified in the bibliographic search, 1,542 were discarded. After full-text analysis, 411 articles were obtained involving over 75,000 subjects. The articles were categorized into fourteen themes. The total scientific productivity showed a constant increase between 2010 and 2016 and an exponential increase between 2017-2022. However, there is a downward trend in the years 2021-2022. The international and national prevalence explains the number of studies associated with type 2 diabetes (DM2), followed by gestational and type 1 diabetes. When analyzing the complications of DM in Chile, its prevalence is not reflected in the number of articles published for each.
    CONCLUSIONS: These results highlight the need to promote research in academic and/or clinical institutions, emphasizing reducing the incidence of DM2 due to the low number of articles with this type of design and the more prevalent complications.
    DOI:  https://doi.org/10.4067/s0034-98872023001201604
  88. Am J Emerg Med. 2024 Sep 04. pii: S0735-6757(24)00442-X. [Epub ahead of print]85 98-107
    Antiviral therapy for COVID-19 virus: A narrative review and bibliometric analysis.
    Saeid Mezail Mawazi, Nousheen Fathima, Syed Mahmood, Sinan Mohammed Abdullah Al-Mahmood.
      The COVID-19 epidemic has become a major international health emergency. Millions of people have died as a result of this phenomenon since it began. Has there been any successful pharmacological treatment for COVID-19 since the initial report on the virus? How many searches are undertaken to address the impact of the infection? What is the number of drugs that have undergone investigation? What are the mechanisms of action and adverse effects associated with the investigated pharmaceuticals used to treat COVID-19? Has the Food and Drug Administration (FDA) approved any medication to treat COVID-19? To date, our understanding is based on a restricted corpus of published investigations into the treatment of COVID-19. It is important to note that no single study comprehensively encompasses all pharmacological interventions for COVID-19. This paper provides an introductory summary of a bibliometric analysis conducted on the data about COVID-19, sourced explicitly from two platforms, namely PubMed and ScienceDirect. The analysis encompasses the period spanning from 2019 to 2022. Furthermore, this study examines the published literature about the pharmacological interventions for the novel coronavirus disease 2019 (COVID-19), explicitly focusing on the safety and effectiveness of different medications such as Remdesivir (marketed as Veklury®), Lopinavir/Ritonavir (commercially known as Kaletra® or Aluvia®), Ribavirin, Favipiravir (marketed as Avigan®), Ivermectin, Casirivimab and Imdevimab (branded as Ronapreve®), Sotrovimab (marketed as Xevudy®), Anakinra, Molnupiravir, Nirmatrelvir/Ritonavir (marketed as Paxlovid®), and Galidesivir. Findings indicate that while Remdesivir and Nirmatrelvir/Ritonavir show significant efficacy in reducing hospitalization and severe outcomes, drugs like Lopinavir/Ritonavir and Ivermectin have inconsistent results. Our insights suggest a multifaceted approach incorporating these therapies can significantly improve patient outcomes. Repurposing drugs has been critical in rapidly responding to COVID-19, allowing existing medications to be used in new ways to combat the virus. Combination therapies and further research are essential to optimize treatment strategies.
    Keywords:  COVID-19; Coronavirus; Pharmacology; SARS-CoV-2; Treatment
    DOI:  https://doi.org/10.1016/j.ajem.2024.09.001
  89. J Surg Res. 2024 Sep 06. pii: S0022-4804(24)00407-4. [Epub ahead of print]302 845-849
    National Institutes of Health Funding Among Society of Asian Academic Surgery Members.
    Ramsha Akhund, Ashba Allahwasaya, Christopher Wu, Rongzhi Wang, Daniel I Chu, Herbert Chen, Jessica Liu McMullin.
       INTRODUCTION: External funding is fundamental to surgeon-scientists and many Society of Asian Academic Surgeons (SAAS) members have received funding through National Institutes of Health (NIH) grants. The amount of funding through NIH awards amongst SAAS members has yet to be evaluated. Our objective was to quantify the amount and type of NIH funding among SAAS members.
    METHODS: A list of all active SAAS members was compiled. The NIH Research Portfolio Online Reporting Tool's Expenditure and Results was queried to identify NIH funding among active members.
    RESULTS: Among 585 active SAAS members, 165 (28%) received NIH funding during their career. Of these, 110 members (66.6%) were male and 55 members (33.3%) were female. A total of 420 NIH grants have been awarded totaling $518.7 million in funding. There are currently 47 active grants totaling $34.1 million in funding. When analyzing by type, there were 226 R research grants, 63 K career development awards, 53 T and F research training and fellowships awards, and 78 other awards. Of the 63 members who received a K award, 35 members (55%) have subsequently received an R award.
    CONCLUSIONS: SAAS members are highly funded with 28% of members having received NIH funding totaling $518.7 million. SAAS' mission is to foster the personal and professional development of academic surgeons and we found that many SAAS members have the experience to mentor other surgeon-scientists through the process of obtaining NIH funding. Participation in organizations like SAAS can help nurture the success of future generations of surgeon-scientists.
    Keywords:  Academic surgery; Mentorship; National Institutes of Health (NIH) funding; Surgical societies
    DOI:  https://doi.org/10.1016/j.jss.2024.07.025
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