bims-evares Biomed News
on Evaluation of research
Issue of 2024–08–25
93 papers selected by
Thomas Krichel, Open Library Society



  1. Sportverletz Sportschaden. 2024 Aug;38(3): 116-128
      Football is a popular sport on a global scale, and injuries sustained by football players have become a significant concern for sports physicians and researchers. Among these injuries, knee injuries are a commonly encountered problem in football players with long-term effects. This paper aims to perform a visual mapping and a bibliometric analysis of research on knee injuries in football, examining the current state and research trends. For this purpose, all publications from the Social Sciences Citation Index (SSCI), Science Citation Index Expanded (SCIE), Emerging Sources Citation Index (ESCI), and Arts & Humanities Citation Index (AHCI) within the Web of Science database were analysed. VOSviewer 1.6.18 was utilised for visualising bibliometric data. A total of 2159 publications were included in the study. The analysis covers publication year, authors, citation counts, and distributions among publishing journals. Authors, institutions, and international relationships were investigated, and keyword analysis, bibliometric coupling, and co-citation network analyses were conducted. The findings reveal that the United States and Australia are the countries with the highest number of publications. From 2018, there has been a noticeable increase in the number of publications. Citation and publication counts reached their peak in 2021. Turkey takes the 28th rank in terms of citation and centrality. The keywords "soccer," "football," "knee", and "anterior cruciate ligament" were found to be intensively used with high centrality. In conclusion, visual mapping through bibliometric analysis highlights the magnitude and diversity of research in the field of knee injuries in football. It emphasises the need for further studies in this area for future researchers, shedding light on important research areas. Moreover, it provides insights into the prevention of such injuries in football players and the development of effective treatment strategies by fostering more knowledge and understanding of knee injuries.
    DOI:  https://doi.org/10.1055/a-2337-5760
  2. J Prosthet Dent. 2024 Aug 15. pii: S0022-3913(24)00495-5. [Epub ahead of print]
       STATEMENT OF PROBLEM: Soft tissue integration helps prevent the bacterial invasion of dental implants, but bibliometric studies on the top 50 most cited articles in the field of soft tissue integration are lacking.
    PURPOSE: The purpose of this bibliometric study was to analyze the 50 most cited articles since 1999 to explore global trends and research hotspots.
    MATERIAL AND METHODS: A specific search strategy of the Science Citation Index Expanded (Web of Science) was devised, and relevant article-based, journal-based, and author-based parameters were analyzed. Correlation analysis was performed (α=.05).
    RESULTS: The number of citations ranged from 71 to 586. Clinical Oral Implants Research was the most cited journal (1722 citations). Berglundh, Tord was the author with the most publications (6 publications) and citations (957 citations). Dental implants and titanium were the keywords with the highest frequency. Switzerland was the country with the highest number of publications (12 publications). Correlation was found between the publication year and average annual citations (P<.001).
    CONCLUSIONS: This study determined the scientific progress in soft tissue integration. The surface design of dental implant materials is essential for the soft tissue integration of dental implants. Soft tissue integration has been a focus of interest in the past few years, but many experiments still need to be done to improve soft tissue compatibility with innovative materials.
    DOI:  https://doi.org/10.1016/j.prosdent.2024.07.013
  3. Front Pharmacol. 2024 ;15 1431958
       Background: Chondrosarcomas are common primary malignant bone tumors; however, comprehensive bibliometric analysis in this field has not yet been conducted. Therefore, this study aimed to explore the research hotspots and trends in the field of chondrosarcoma through bibliometric analysis to help researchers understand the current status and direction of research in the field.
    Methods: Articles and reviews related to chondrosarcoma published between 2003 and 2022 were retrieved from the Web of Science. Countries, institutions, authors, journals, references, and keywords in this field were visualized and analyzed using CtieSpace and VOSviewer software.
    Results: Between 2003 and 2022, 4,149 relevant articles were found. The number of articles published on chondrosarcoma has increased significantly annually, mainly from 569 institutions in China and the United States, and 81 in other countries. In total, 904 authors participated in the publication of studies related to chondrosarcomas. Over the past 20 years, articles on chondrosarcoma have been published in 958 academic journals, with Skeletal Radiology having the highest number of publications. Furthermore, keywords such as "gene expression," "radiotherapy," "experience," and "apoptosis" have been popular in recent years.
    Conclusion: Over the past 20 years, the global trend in chondrosarcoma research has primarily been clinical research, with basic research as a supplement. In the future, communication and exchange between countries and institutions should be strengthened. Further, the future main research hotspots in the field of chondrosarcoma include mutated genes and signaling pathways, precision surgical treatment, proton therapy, radiation therapy, chemotherapy, immunotherapy, and other aspects.
    Keywords:  3D printing; bibliometric analysis; bone tumor; cancer; chondrosarcoma
    DOI:  https://doi.org/10.3389/fphar.2024.1431958
  4. Front Neurosci. 2024 ;18 1409492
       Background: Transcranial alternating current stimulation (tACS) can apply currents of varying intensity to the scalp, modulating cortical excitability and brain activity. tACS is a relatively new neuromodulation intervention that is now widely used in clinical practice. Many papers related to tACS have been published in various journals. However, there are no articles that objectively and directly introduce the development trend and research hotspots of tACS. Therefore, the aim of this study is to use CiteSpace to visually analyze the recent tACS-related publications, systematically and in detail summarize the current research hotspots and trends in this field, and provide valuable information for future tACS-related research.
    Material and methods: The database Web of Science Core Collection Science Citation Index Expanded was used and searched from build to 4 August 2023. Using the CiteSpace to analyze the authors, institutions, countries, keywords, co-cited authors, journals, and references.
    Results: A total of 677 papers were obtained. From 2008 to 2023, the number of publications shows an increasing trend, albeit with some fluctuations. The most productive country in this field was Germany. The institution with the highest number of publications is Carl von Ossietzky University of Oldenburg (n = 50). According to Bradford's law, 7 journals are considered core journals in the field. Herrmann, CS was the author with the most publications (n = 40), while Antal, A was the author with the highest number of co-citations (n = 391) and betweenness centrality (n = 0.16). Disease, neural mechanisms of the brain and electric stimulation are the major research areas in the field. The effect of tACS in different diseases, multi-site stimulation, combined treatment and evaluation are the future research hotspots and trends.
    Conclusion: tACS has research value and research potential, and more and more researchers are paying attention to it. The findings of this bibliometric study provide the current status and trends in the clinical research of tACS and may help researchers to identify hotspots s and explore new research directions in this field.
    Keywords:  CiteSpace; bibliometrics; oscillations; transcranial alternating current stimulation; visual analysis
    DOI:  https://doi.org/10.3389/fnins.2024.1409492
  5. Front Surg. 2024 ;11 1435955
      Recent years have seen the publication of numerous papers on the application of three-dimensional (3D) printing in plastic surgery. Despite this growing interest, a comprehensive bibliometric analysis of the field has yet to be conducted. To address this gap, we undertook a bibliometric study to map out the knowledge structure and identify research hotspots related to 3D printing in plastic surgery. We analyzed publications from 1995 to 2024, found in the Web of Science Core Collection (WoSCC), utilizing tools such as VOSviewer, CiteSpace, and the R package "bibliometrix". Our analysis included 1,057 documents contributed by 5,545 authors from 1,620 organizations across 71 regions, and these were published in 400 journals. We observed a steady growth in annual publications, with Europe, Asia, North America, and Oceania leading in research output. Notably, Shanghai Jiao Tong University emerged as a primary research institution in this domain. The Journal of Craniofacial Surgery and Journal of Oral and Maxillofacial Surgery have made significant contributions to the field, with Thieringer, Florian M being the most prolific and frequently cited author. Key areas of focus include medical education and surgical procedures, with "3D printing", "virtual surgical planning" and "reconstructive/orthognathic surgery" highlighted as future research hotspots. Our study provides a detailed bibliometric analysis, revealing the evolution and progress of 3D printing technologies in plastic surgery. As these technologies continue to advance, their impact on clinical practice and patient lives is expected to be profound.
    Keywords:  augmented reality; bibliometric analysis; citation analysis; plastic surgery; three-dimensional (3D) printing
    DOI:  https://doi.org/10.3389/fsurg.2024.1435955
  6. Discov Oncol. 2024 Aug 19. 15(1): 359
       OBJECTIVE: Bibliometrics was employed in this study to determine the research trends in the worldwide application of 3D printing technology to treat bone tumors over the previous 10 years.
    METHODS: Published from 2013 to 2022, the papers related to bone tumors treated with 3D printing were located in Web of Science Core Collection (WoSCC), PubMed, and Scopus. The screened articles were included in this bibliometric study. From these papers in WoSCC, information on annual publications, journals, keywords, countries, authors, institutions, and cited references were extracted and visualized with CiteSpace (version 6.1.R6) software to investigate the state of bone tumor treatment using 3D printing as well as research hotspots. The Carrot2 online visualization tool and Vosviewer software (version 1.6.20) were employed to visualize the publications from PubMed and Scopus, respectively, in order to ascertain the most popular research topics from both databases.
    RESULTS: A total of 606, 233, and 364 publications were obtained from WoSCC, PubMed, and Scopus, respectively, between the years 2013 and 2022. In WoSCC, the peak number of publications was found in 2021, with 145 publications published. Acta Biomaterialia (11 publications) and World Neurosurgery (10 publications) were the most prolific journals, and Biomaterials was the journal cited the most (244 times). Yong Zhou was the most productive author with 14 publications, while Kwok-Chuen Wong (69 citations) and William F Enneking, (69 citations) possessed the most citations. The country with the largest quantity of publications was China (207). Among all institutions, Shanghai Jiao Tong University produced the most publications (29). Rapid prototyping was the keyword with the strongest citation burst (4.73). 'Reconstruction', 'surgery', 'resection', and 'design' caught the significant attention of researchers. 3D-printed materials, pelvic reconstruction, mandibular reconstruction, computer-assisted surgical techniques, photothermal therapy, and in vitro experiments were recognized as hot subjects and trends in current research. The most frequently occurring topics in Scopus are not significantly different from those found in WoSCC. The most prevalent research areas in PubMed encompass implant, patient-specific, bioceramic, models, and pelvic.
    Keywords:  3D printing; Bibliometric analysis; Bone tumor
    DOI:  https://doi.org/10.1007/s12672-024-01207-6
  7. Hosp Top. 2024 Aug 20. 1-13
      This study examines the concept of health advocacy and explores related scholarly material to understand its evolution from 1977 to 2021. The bibliometric analysis investigates the publication trends, most relevant authors, keywords-based clusters, research trends, author productivity, and future research areas in health advocacy. The relevant articles were extracted from the Scopus database and analyzed to identify and explore the most active authors, author-wise contribution to the sources, sub-research topics, core sources, top authors' production over time, global cited documents, thematic maps, word cloud, country-wise collaboration network and map, author keywords-based network, historiograph, and spectroscope. The study finds that health advocacy as a concept is under-explored and thus warrants a need for future research work. Limited authors have contributed to this theme, and the continuity of publication needs to be improved. The study highlights that there needs to be a robust framework to assess, evaluate, and implement health advocacy. The researchers are limited to only a few authors who have published in limited journals. The current study brings out the need for research and publications on health advocacy to develop a framework for assessing and implementing health advocacy. Also, the study highlights emerging themes of Coronavirus pandemic and emergency and disaster preparation. The niche themes that emerged during the survey highlight keywords such as agenda-setting and maternal health.
    Keywords:  Health advocacy; bibliometric analysis; equity; health policy
    DOI:  https://doi.org/10.1080/00185868.2024.2390956
  8. Adv Skin Wound Care. 2024 Sep 01. 37(9): 1-7
       OBJECTIVE: To review research on pressure injury (PI) prevention published between 2018 and 2023 using bibliometric analysis methods to identify trends in the field over the past 5 years.
    METHODS: The author queried the Web of Science database using the keywords "pressure injury or pressure ulcer and prevention" to access the bibliometric data of relevant studies. The program RStudio version 4.2.1 and the utility package Biblioshiny were used for data analysis.
    RESULTS: A total of 1,110 English-language studies that focused on PI prevention were analyzed, including articles, reviews, proceeding papers, and early access articles. Articles were published by 114 sources. The average publication age was 2.57 years, and the average number of citations per publication was 5.88. The average number of authors per publication was 4.63, with an international coauthorship rate of 19.46%. The most cited articles were prevalence and incidence studies, systematic reviews, and meta-analyses. An examination of journals with research related to PI prevention highlighted the Journal of Tissue Viability and Advances in Skin & Wound Care as prominent journals.
    CONCLUSIONS: Researchers and clinical nurses working in the field of PI prevention should research the identified trending topics (eg, COVID-19, intensive care, and classification) and aim to publish in journals with a high number of citations or substantive contributions in this area.
    DOI:  https://doi.org/10.1097/ASW.0000000000000203
  9. World J Psychiatry. 2024 Aug 19. 14(8): 1267-1284
       BACKGROUND: Overweight/obesity combined with depression among children and adolescents (ODCA) is a global concern. The bidirectional relationship between depression and overweight/obesity often leads to their comorbidity. Childhood and adolescence represent critical periods for physical and psychological development, during which the comorbidity of overweight/obesity and depression may increase the risk of adverse health outcomes.
    AIM: To evaluate the relationship between ODCA, we conduct a bibliometric analysis to aid in formulating prevention and treatment strategies.
    METHODS: From 2004 to 2023, articles related to ODCA were selected using the Science Citation Index Expanded from the Web of Science Core Collection. Bibliometric analysis of relevant publications, including countries/regions, institutions, authors, journals, references, and keywords, was conducted using the online bibliometric analysis platforms, CiteSpace, VOSviewer, and bibliometrix.
    RESULTS: Between 2004 and 2023, a total of 1573 articles were published on ODCA. The United States has made leading contributions in this field, with Harvard University emerging as the leading contributor in terms of research output, and Tanofsky being the most prolific author. The J Adolescent Health has shown significant activity in this domain. Based on the results of the keyword and reference analyses, inequality, adverse childhood experiences, and comorbidities have become hot topics in ODCA. Moreover, the impact of balanced-related behavior and exploration of the biological mechanisms, including the potential role of key adipocytokines and lipokines, as well as inflammation in ODCA, have emerged as frontier topics.
    CONCLUSION: The trend of a significant increase in ODCA publications is expected to continue. The research findings will contribute to elucidating the pathogenic mechanisms of ODCA and its prevention and treatment.
    Keywords:  Adolescents; Bibliometric analysis; Children; Depression; Obesity; Overweight; Research trends
    DOI:  https://doi.org/10.5498/wjp.v14.i8.1267
  10. Front Oncol. 2024 ;14 1439209
       Background: Bone metastases of lung cancer (BMLC) severely diminish patients' quality of life due to bone-related events, and the lack of clear guidelines globally regarding medical and surgical treatment significantly reduces patient survival. While knowledge about BMLC has grown exponentially over the past two decades, a comprehensive and objective bibliometric analysis remains absent.
    Methods: A comprehensive bibliometric analysis was conducted on relevant literature on BMLC extracted from the Web of Science database from 2004 to 2023 by Biblioshiny, VOSviewer, Scimago Graphica, CiteSpace, and Microsoft Office Excel Professional Plus 2016 software. 936 papers related to BMLC were extracted from the Web of Science Core Collection (WoSCC). The number of publications, countries, institutions, global collaborations, authors, journals, keywords, thematic trends, and cited references were then visualized. Finally, the research status and development direction in the last 20 years were analyzed.
    Results: This study included a total of 936 papers on BMLC from 2004 to 2023. There has been a steady increase in global publications each year, peaking in 2021. China had the highest number of publications, followed by Japan and the United States. Additionally, China had the most citations with an H-index of 35, while the US followed with an H-index of 34, highlighting their significant contributions to the field. "Frontiers in Oncology" had the highest number of publications. CiteSpace analysis identified "lung cancer," "bone metastasis," and "survival" as the top high-frequency keywords, encapsulating the core research focus. Keyword clustering analysis revealed six main clusters representing the primary research directions. Burst analysis of keywords showed that "skeletal complications" had the highest burst intensity from 2005 to 2013, while recent research trends include "immunotherapy" and "denosumab," with bursts from 2021 to 2023. Trend topic analysis indicated that "non-small cell lung cancer," "immunotherapy," and "immune checkpoint inhibitors" represent the cutting-edge research directions in this field.
    Conclusion: This article reveals the current status and trend of research on BMLC, which is increasing worldwide. China and the United States have contributed the most, but international cooperative research on BMLC should be strengthened. The pathogenesis, early prevention, and individualized treatment of BMLC need to be strengthened for further study, and immunotherapy is the next hotspot of lung cancer bone metastasis research.
    Keywords:  bibliometrics; bone metastasis; current state; lung cancer; research
    DOI:  https://doi.org/10.3389/fonc.2024.1439209
  11. Heliyon. 2024 Aug 15. 10(15): e35212
       Background: Various factors play crucial roles in aneurysm development and prognosis. Macrophages have recently emerged as a major research focus. Despite the numerous studies on the role and function of macrophages in aneurysm pathogenesis, no bibliometric analyses have focused on this topic.
    Objective: This study aimed to analyze articles related to macrophages and aneurysms to reveal trends, hotspots, and new frontiers in macrophage-related aneurysm research.
    Methods: We retrieved and incorporated 1211 articles from the Science Citation Index Expanded database of the Web of Science Core Collection between 1999 and 2022. The data were analyzed and visualized using CiteSpace and VOSviewer, and Microsoft Excel 2019 was used to plot the data.
    Results: The most influential articles were published between 1999 and 2022, with a total citation count of 43870. This study encompassed a comprehensive analysis of 74 research directions. The year with the highest number of publications was 2021 when 109 articles were published. 'ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY' journal has made significant contributions by publishing the highest number of articles (99 articles), while funding support primarily came from the National Institutes of Health and United States Department of Health and Human Services. The United States exerted a substantial influence within this field, with a total publication count of 453 publications and the highest centrality value (0.63). Recent studies have focused on understanding the developmental processes underlying aneurysms and devising preventive measures to effectively impede disease progression.
    Conclusions: Our analysis demonstrates the rapid growth in research exploring the relationship between macrophages and aneurysms over the past two decades. Continued exploration and collaboration among different specialties and manufacturers will facilitate innovative approaches for effective management strategies that target patients with diverse forms of aneurysms.
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35212
  12. Heliyon. 2024 Aug 15. 10(15): e35107
       Background: The resilience of healthcare workers has gained increasing attention, yet comprehensive studies focusing on recent trends and developments are scarce. We conducted an extensive bibliometric analysis from inception to 2023 to address this gap.
    Methods: Publications on healthcare workers' resilience were extracted from the Web of Science Core Collection database. Bibliometric analysis was conducted with CiteSpace, VOSviewer, and Scimago Graphica, focusing on annual publications, country/region, institution, journal, author, keyword analysis, and reference co-citation analysis related to resilience in healthcare workers.
    Results: The analysis included 750 documents, revealing a general upward trend in publications across 67 countries/regions, 1,251 institutions, and 3,166 authors. The USA and China emerged as the top contributors, with 192 and 168 publications, respectively. Based on keyword analysis and reference co-citation analysis, the focus areas include the Resilience Scale, the impact of the COVID-19 pandemic on HCWs and their resilience, and nurse resilience.
    Conclusion: This study highlights the growing interest in healthcare workers' resilience by using bibliometric and visualization techniques for effective analysis. This paper will enhance scholars' understanding of the dynamic evolution of healthcare workers' resilience and identify emerging research topics.
    Keywords:  Bibliometric; CiteSpace; Healthcare workers; Resilience; VOSviewer
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35107
  13. Heliyon. 2024 Aug 15. 10(15): e35446
       Background and objective: Biologics have revolutionized the management of plaque psoriasis and are flourishing. We aimed to construct a knowledge structure in this field through bibliometrics, analyze research trends and cutting-edge hotspots to inspire future research directions, and provide valuable references for clinical decisions.
    Methods: Publications on biologics for plaque psoriasis in the Web of Science database core collection from 2004 to 2023 were searched. Bibliometric analysis and scientific knowledge mapping were performed with R, CiteSpace, and VOSviewer software.
    Results: 2,672 articles written by 9,474 authors from 67 countries were included in the study. The number of annual publications has steadily increased over the last 20 years. The most prolific countries, institutions, and authors were the United States, Novartis, and Prof. Reick K., respectively. Reference analysis categorized the research base of the field into 10 main clusters. "Efficacy" and "safety" were the most frequent keywords, and cluster analysis categorized the research in this area into four groups. Burst detection captured current hot keywords including interleukin (IL)-17 inhibitors, IL-23 inhibitors, "drug survival," "discontinuation," "Covid-19," "real-world," and "clinical features."
    Conclusion: Global publications on biologics research in plaque psoriasis have grown steadily and rapidly over the past two decades. Efficacy and safety are the highest topics of concern for researchers, and IL-17 inhibitors, IL-23 inhibitors, real-world studies, efficacy prediction, and retreatment after biologics failure or discontinuation are current research hotspots.
    Keywords:  Bibliometrics; Biologics; Plaque psoriasis; Research hotspots; Visualization analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35446
  14. ARYA Atheroscler. 2024 Mar-Apr;20(2):20(2): 17-30
       BACKGROUND: The present study was conducted to investigate the scientific contributions of Iranians in the field of cardiovascular research, as indexed in the Scopus database, using bibliometric and altmetric methods.
    METHODS: This applied study was conducted with a scientometric approach, utilizing bibliometric and altmetric indicators. The research population consisted of the scientific works of Iranian researchers in the field of cardiovascular diseases, indexed in the Scopus database over a period of 47 years. For bibliometric analysis and the generation of co-citation, co-occurrence, and co-authorship maps, the authors employed VOS Viewer software and the bibliometrix package in the R programming language. In the final stage, articles mentioned on social media were analyzed and evaluated using an altmetric approach.
    RESULTS: The results indicated that the commencement point for the publication of documents was 1975, and there has been a steep increase in recent years. Moreover, the documents were primarily research articles out of 6853 retrieved documents, and a limited number of documents were single-authored. Other findings also revealed the co-authorship map of authors and the co-occurrence of words, highly cited authors and institutions, and highly frequent keywords, signifying the scientific collaboration of Iranian researchers with the United States and England. Altmetric analysis also demonstrated that 43.41% of documents were shared at least once on social media and had an Altmetric Attention score. Furthermore, the analysis of altmetric indices showed that Mendeley, Twitter, and News had the highest share of document mentions on social media, respectively.
    CONCLUSION: The findings of the study can offer valuable information to researchers, managers, and policy makers to become aware of the current state of research in the field of cardiovascular diseases and implement the necessary policies to inform society and enhance public health status.
    Keywords:  Altmetric; Bibliometrics; Cardiovascular Diseases; Publications; Scientometrics; Social Media
    DOI:  https://doi.org/10.48305/arya.2024.42080.2918
  15. World J Gastrointest Oncol. 2024 Aug 15. 16(8): 3705-3715
       BACKGROUND: Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related death. Over the past two decades, numerous researchers have provided important evidence regarding the role of tight junction (TJ) proteins in the occurrence and progression of CRC. The causal relationship between the presence of specific TJ proteins and the development of CRC has also been confirmed. Despite the large number of publications in this field, a bibliometric study to review the current state of research and highlight the research trends and hotspots in this field has not yet been performed.
    AIM: To analyze research on TJs and CRC, summarize the field's history and current status, and predict future research directions.
    METHODS: We searched the Science Citation Index Expanded database for all literature on CRC and TJs from 2001-2023. We used bibliometrics to analyze the data of these papers, such as the authors, countries, institutions, and references. Co-authorship, co-citation, and co-occurrence analyses were the main methods of analysis. CiteSpace and VOSviewer were used to visualize the results.
    RESULTS: A total of 205 studies were ultimately identified. The number of publications on this topic has steadily increased since 2007. China and the United States have made the largest contributions to this field. Anticancer Research was the most prolific journal, publishing 8 articles, while the journal Oncogene had the highest average citation rate (68.33). Professor Dhawan P was the most prolific and cited author in this field. Co-occurrence analysis of keywords revealed that "tight junction protein expression", "colorectal cancer", "intestinal microbiota", and "inflammatory bowel disease" had the highest frequency of occurrence, revealing the research hotspots and trends in this field.
    CONCLUSION: This bibliometric analysis evaluated the scope and trends of TJ proteins in CRC, providing valuable research perspectives and future directions for studying the connection between the two. It is recommended to focus on emerging research hotspots, such as the correlations among intestinal microbiota, inflammatory bowel disease, TJ protein expression, and CRC.
    Keywords:  Bibliometric analysis; Colorectal cancer; Hot spots; Research trends; Tight junctions
    DOI:  https://doi.org/10.4251/wjgo.v16.i8.3705
  16. World J Gastrointest Oncol. 2024 Aug 15. 16(8): 3732-3737
      The primary aim of this study was to analyze the evolving trends and key focal points in research on cellular metabolism of colorectal cancer (CRC). Relevant publications on cellular metabolism in CRC were sourced from the Science Citation Index Expanded within the Web of Science Core Collection database. Bibliometric analysis and visualization were conducted using VOSviewer (version 1.6.18) software and CiteSpace 6.1.R6 (64-bit) Basic. A comprehensive compilation of 4722 English-language publications, covering the period from January 1, 1991 to December 31, 2022, was carefully identified and included in the analysis. Among the authors, "Ogino, Shuji" contributed the most publications in this field, while "Giovannucci, E" garnered the highest number of citations. The journal "Cancer Research" ranked first in both publication volume and citations. Institutionally, "Shanghai Jiao Tong University" emerged as the top contributor in terms of published articles, while "Harvard University" led in citation impact. In country-based analysis, the United States held the top position in both publication output and citations, closely followed by China. The increasing recognition of the significance of cellular metabolism in CRC underscores its potential for novel therapeutic approaches aimed at improving CRC management and prognosis.
    Keywords:  Bibliometric analysis; Cellular metabolism; Colorectal cancer; Metabolic reprogramming
    DOI:  https://doi.org/10.4251/wjgo.v16.i8.3732
  17. J Cancer Res Clin Oncol. 2024 Aug 22. 150(8): 393
       BACKGROUND/OBJECTIVE: Omics technology has become a widely applied biological science that can be used to study the etiology, pathogenesis, and treatment of osteosarcoma(OS). Bibliometric analysis is still blank in this field.This study aimed to access the trends and hotspots of omics in OS research through the bibliometric analysis method.
    METHODS: Relevant articles and reviews from 1999 to 2023 were retrieved from the Web of Science Core Collection. The data were processed with CiteSpace, and some graphs were generated with Graphpad, VOSviewer, Scimago Graphica, Bibliometrix and R Studio.
    RESULTS: A total of 1581 papers were included. China (569, 36.0%) and the United States (523, 33.1%) took the dominant position in the number of published papers, and the links between countries most frequently occurred between North America and East Asia, and between Australia and Europe. Top institutions with the highest number of publications were almost located in the United States, with The University of Texas MD Anderson Cancer Center contributing the most (44, 2.78%). Among the researchers in this field, Cleton-Jansen AM was the author with the highest number of articles in the field (20, 1.27%). According to the keyword cluster analysis, most studies focused on the "comparative genomic hybridization" before 2012. The latest surge words "tumor microenvironment" and "immune infiltration" in the keyword heatmap indicate future research directions.
    CONCLUSION: Our study provided the current status of the omics research in OS on a global level and the hottest directions. The field of omics in OS was developing rapidly, and the main focuses of research were revealing the characteristics of tumor microenvironment of OS and how to activate the immune system to fight cancer cells. Research on the immune microenvironment and its relationship with genetic aberrations of OS will be a priority in the future.
    Keywords:  Bibliometrics; Immune microenvironment; Omics; Osteosarcoma
    DOI:  https://doi.org/10.1007/s00432-024-05898-w
  18. Front Oncol. 2024 ;14 1361530
       Background: Glioblastoma (GBM) is one of the common malignant tumors of the central nervous system (CNS), characterized by rapid proliferation, heterogeneity, aggressiveness, proneness to recurrence after surgery, and poor prognosis. There is increasing evidence that tumorigenesis is inextricably linked to immune escape, and immunotherapy is undoubtedly an important complement to clinical treatment options for GBM, and will be a focus and hot topic in GBM treatment research. The purpose of this study was to visualize and analyze the scientific results and research trends of immunotherapy for GBM.
    Methods: Publications concerning immunotherapy for GBM were retrieved from the Web of Science Core Collection (WOScc) database. Bibliometric and visual analysis was performed mainly using CiteSpace and R software, and the Online Analysis Platform of Literature Metrology (https://bibliometric.com/app) for countries/regions, authors, journals, references and keywords related to publications in the field.
    Results: Among totally 3491 publications retrieved in this field, 1613 publications were finally obtained according to the screening criteria, including 1007 articles (62.43%) and 606 reviews (37.57%). The number of publications increased year by year, with an average growth rate (AGR) of 17.41%. Such a number was the largest in the USA (717, 44.45%), followed by China (283, 17.55%), and the USA showed the strongest international collaboration. Among the research institutions, Duke Univ (94, 5.83%) was the largest publisher in the field, followed by Harvard Med Sch (70, 4.34%). In addition, the most prolific authors in this field were OHN H SAMPSON (51) and MICHAEL LIM (43), and the degree of collaboration (DC) between authors was 98.26%. Among the co-cited authors, STUPP R (805) was the most cited author, followed by REARDON DA (448). The journal with the most published publications was FRONTIERS IN IMMUNOLOGY (75), and the most cited journal in terms of co-citation was CLIN CANCER RES (1322), followed by CANCER RES (1230). The high-frequency keyword included glioblastoma (672) and immunotherapy (377). Cluster analysis was performed on the basis of keyword co-occurrence analysis, yielding 17 clusters, based on which the current research status and future trends in the field of immunotherapy for GBM were identified.
    Conclusion: Immunotherapy is currently a novel treatment strategy for GBM that has attracted much attention. In the future, it is necessary to strengthen cooperation and exchanges between countries and institutions towards relevant research to promote the development of this field. Immunotherapy is expected to be an important part of the future treatment strategy for GBM, and it has already become a hot spot of current research and will be the key focus of future research.
    Keywords:  CiteSpace; bibliometrics; glioblastoma; immunotherapy; research hotspots
    DOI:  https://doi.org/10.3389/fonc.2024.1361530
  19. Front Psychiatry. 2024 ;15 1432792
       Background: Depression is a chronic psychiatric condition that places significant burdens on individuals, families, and societies. The rapid evolution of non-invasive brain stimulation techniques has facilitated the extensive clinical use of Transcranial Magnetic Stimulation (TMS) for depression treatment. In light of the substantial recent increase in related research, this study aims to employ bibliometric methods to systematically review the global research status and trends of TMS in depression, providing a reference and guiding future studies in this field.
    Methods: We retrieved literature on TMS and depression published between 1999 and 2023 from the Science Citation Index Expanded (SCIE) and Social Science Citation Index (SSCI) databases within the Web of Science Core Collection (WoSCC). Bibliometric analysis was performed using VOSviewer and CiteSpace software to analyze data on countries, institutions, authors, journals, keywords, citations, and to generate visual maps.
    Results: A total of 5,046 publications were extracted covering the period from 1999 to 2023 in the field of TMS and depression. The publication output exhibited an overall exponential growth trend. These articles were published across 804 different journals, BRAIN STIMULATION is the platform that receives the most articles in this area. The literature involved contributions from over 16,000 authors affiliated with 4,573 institutions across 77 countries. The United States contributed the largest number of publications, with the University of Toronto and Daskalakis ZJ leading as the most prolific institution and author, respectively. Keywords such as "Default Mode Network," "Functional Connectivity," and "Theta Burst" have recently garnered significant attention. Research in this field primarily focuses on TMS stimulation patterns, their therapeutic efficacy and safety, brain region and network mechanisms under combined brain imaging technologies, and the modulation effects of TMS on brain-derived neurotrophic factor (BDNF) and neurotransmitter levels.
    Conclusion: In recent years, TMS therapy has demonstrated extensive potential applications and significant implications for the treatment of depression. Research in the field of TMS for depression has achieved notable progress. Particularly, the development of novel TMS stimulation patterns and the integration of TMS therapy with multimodal techniques and machine learning algorithms for precision treatment and investigation of brain network mechanisms have emerged as current research hotspots.
    Keywords:  bibliometrics; brain mechanisms; depressive disorder; efficacy; transcranial magnetic stimulation; visualization analysis
    DOI:  https://doi.org/10.3389/fpsyt.2024.1432792
  20. Cureus. 2024 Jul;16(7): e64785
      Survey research enables the gathering of information on individual perspectives in a large cohort. It can be epidemiological, attitude or knowledge focussed. Assessment of survey studies sampling neurosurgeons is currently lacking in the literature. This study aimed to highlight the characteristics, quality, and citation predictors of the most influential survey research studies published in the neurosurgical literature. Using PubMed and Google Scholar, the 50 most cited survey research publications were identified and reviewed. Data relating to the characteristics of the articles, participants and questionnaires were retrieved. The studies' quality and citation patterns were assessed. The median articles' age and publishing journal impact factor (IF) were 15.5 years and 2.82, respectively. Thirty-two (64%) articles were first authored by researchers from the USA while 28(56%) studies were focussed on specific disease management. The median number of participants and response rates were 222 and 51%, respectively. A full version of the questionnaire was provided in 18 (36%) articles. Only four (8%) articles reported validation of the questionnaire. The overall quality of reporting of the surveys was considered fair (based on good grading in five parameters, fair grading in one parameter, and poor grading in four parameters). The median citation number was 111. The citation analysis showed that the participant number, article age (≥15.5 years), and questionnaire category (surgical complications) were significant predictors of citation numbers. The citation rates were not influenced by the response rates or the journal's IF. In conclusion, high-impact survey publications in the neurosurgical literature were moderately cited and of fair quality. Their citation numbers were not affected by response rates but were positively influenced by the publication age, number of participants, and by novel data or the questions raised in the survey category. Surveys are valuable forms of research that require extensive planning, time, and effort in order to produce meaningful results. Increasing awareness of the factors that could affect citations may be useful to those who wish to undertake survey research.
    Keywords:  bibliometrics; citation rates; neurosurgical journals; publication trends; pubmed; spine journals; survey questionnaire
    DOI:  https://doi.org/10.7759/cureus.64785
  21. Front Psychiatry. 2024 ;15 1436906
       Background: Schizophrenia is a chronic mental illness that affects millions of individuals worldwide. The etiological origin of schizophrenia is heterogeneous, but it has been shown to be associated with dysfunction in serotonin activity, serotonin receptors, and serotonin metabolism in the brain. Bibliometric analysis is a tool used to scrutinise and analyse research activities and evidence in a specific research area. No existing bibliometric analyses have considered both serotonin and schizophrenia.
    Methods: We conducted a bibliometric analysis including 12,027 studies related to the schizophrenia-serotonin link published from the inception of the study to 2023 and available in the Scopus database. We used VOSviewer software to identify global trends, analyse the author and editors keywords, the most cited articles and author, as well as the most productive institutes and journals publishing research on schizophrenia-serotonin link.
    Results: Most publications related to the link between schizophrenia and serotonin are focused on adult humans and examine topics such as antipsychotic agents, depression, and serotonin uptake inhibitors. The Journal of Clinical Psychiatry has published the most papers on the schizophrenia-serotonin relationship. Among nations, the United States is the leader in publications. King's College London is the institution with the highest number of publications, and H. Y. Meltzer is the most influential author. Growing trends in schizophrenia-serotonin research are personalised medicine, alternative medicine, transcranial magnetic stimulation, artificial intelligence, nervous system inflammation, brain-gut axis, and the gut microbiome.
    Conclusion: Since 1950, there have been several fluctuations in the number of published studies related to schizophrenia and serotonin. We believe that the development of novel medications and treatments for schizophrenia will be increased in the future, as well as research into genetic risks, psychological factors, and cranial neuroimaging components. Future schizophrenia and serotonin research is likely to focus on personalised medicine, alternative therapies, novel pathogenesis of schizophrenia, and the use of emerging technologies such as artificial intelligence.
    Keywords:  VOSviewer; bibliometric analysis; schizophrenia; scopus; serotonin
    DOI:  https://doi.org/10.3389/fpsyt.2024.1436906
  22. Cancer Rep (Hoboken). 2024 Aug;7(8): e2146
       BACKGROUND: Despite considerable progress in cancer immunotherapy, it is not available for many patients. Resistance to immune checkpoint blockers arises from the intricate interactions between cancer and its microenvironment. Metabolic reprogramming in tumor and immune cells in the tumor microenvironment (TME) influences anti-tumor immune responses by remodeling the immune microenvironment. Metabolic reprogramming has emerged as an important hallmark of tumorigenesis. However, few studies have focused on the TME and metabolic reprogramming. Therefore, we aimed to explore the current research status and popular topics in TME-related metabolic reprogramming over a 20 years using a bibliometric approach.
    METHODS: Studies focusing on metabolic reprogramming and TME were searched using the Web of Science Core Collection database. Bibliometric and visual analyses of the articles and reviews were performed using Bibliometrix, VOSviewer, and CiteSpace.
    RESULTS: In total, 4726 articles published between 2003 and 2022 were selected. The number of publications and citations has increased annually. Cooperation network analysis indicated that the United States holds the foremost position in metabolic reprogramming and TME research with the highest volume of publications and citations, thus exerting the greatest influence. Among these institutions, Fudan University displayed the highest level of productivity. Frontiers in Immunology showed the highest degree of productivity in this field. Ho Ping-Chih made the most article contributions, and Pearce Edward J. was the most co-cited author. Four clusters were obtained after a cluster analysis of the authors' keywords: TME, metabolic reprogramming, immunometabolism, and immunity. Immunometabolism, glycolysis, immune cells, and tumor-associated macrophages are relatively recent keywords that have attracted increasing attention.
    CONCLUSIONS: A comprehensive landscape of advancements in metabolic reprogramming and the TME was evaluated, which provided crucial information for scholars to further advance this promising field. Further research should explore new topics related to immunometabolism in the TME using a transdisciplinary approach.
    Keywords:  bibliometric analysis; immunotherapy; metabolic reprogramming; tumor microenvironment; tumor‐infiltrating immune cells
    DOI:  https://doi.org/10.1002/cnr2.2146
  23. Discov Oncol. 2024 Aug 22. 15(1): 364
       BACKGROUND: Radiation-induced brain injury (RIBI) is a debilitating sequela after cranial radiotherapy. Research on the topic of RIBI has gradually entered the public eye, with more innovations and applications of evidence-based research and biological mechanism research in the field of that. This was the first bibliometric analysis on RIBI, assessing brain injury related to radiation articles that were published during 1998-2023, to provide an emerging theoretical basis for the future development of RIBI.
    METHODS: Literature were obtained from the Web of Science Core Collection (WOSCC) from its inception to December 31, 2023. The column of publications, author details, affiliated institutions and countries, publication year, and keywords were also recorded.
    RESULTS: A total of 2543 journal articles were selected. The annual publications on RIBI fluctuated within a certain range. Journal of Neuro-oncology was the most published journal and Radiation Oncology was the most impactful one. LIMOLI CL was the most prolific author with 37 articles and shared the highest h-index with BARNETT GH. The top one country and institutions were the USA and the University of California System, respectively. Clusters analysis of co-keywords demonstrated that the temporal research trends in this field primarily focused on imaging examination and therapy for RIBI.
    CONCLUSION: This study collects, visualizes, and analyzes the literature within the field of RIBI over the last 25 years to map the development process, research frontiers and hotspots, and cutting-edge directions in clinical practice and mechanisms related to RIBI.
    Keywords:  Bibliometric analysis; Clinical practice; Hotspots; Mechanisms; Radiation-induced brain injury
    DOI:  https://doi.org/10.1007/s12672-024-01223-6
  24. PLoS One. 2024 ;19(8): e0308713
      Using bibliometric analysis of large-scale publication data is a simple approach to exploring gender-related trends, especially gender equality in academic publishing. The aim of this study is to investigate gender trends in the fields of bio-economy and rural development sciences in two under develop regions as Latin America and Africa. This study examines gender differences in these fields in order to: (1) recognize the contribution of female researchers in bioeconomy and rural development, (2) explore the relational structure of gender aspects in academic publications, (3) identify trends in female authorship in these scientific research fields over time, and finally (4) identify gender potentials for women to become more visible in these fields of study. To achieve these objectives, we used bibliometric tools to analyses 1891 publication records in bioeconomy and rural development. After cleaning the database of full names of authors of academic publications relevant to the field studies, we performed a series of statistical analyses in R and SPSS software, such as Lotkas distribution, network analysis, co-authorship analysis and spatial distribution of authors in the study. The results show that the number of male authors is almost three times higher than the number of female authors, suggesting that women are under-represented in the fields studied. Men occupy the most important position of authorship in scientific articles; publications with corresponding male authors were found in 1389 out of 1891 publications related to the bio-economy and rural development. In terms of geographical regions, publications with female authors were more prevalent in European and North American areas, with a small exception in some developing countries such as Argentina and South Africa. In terms of research networks, from the total number of authors evaluated, only 23% are female authors on the map of research influence. This indicates that there is a significant gap to be filled in the promotion of scholarly impact through the sharing of knowledge and expertise among authors.
    DOI:  https://doi.org/10.1371/journal.pone.0308713
  25. Clin Exp Med. 2024 Aug 23. 24(1): 196
      The utilization of artificial intelligence (AI) in rheumatic diseases has enhanced the diagnostic accuracy of rheumatic diseases, enabled the prediction of patient outcomes, expanded treatment options, and facilitated the provision of individualized medical solutions. The research in this field has been progressively growing in recent years. Consequently, there is a need for bibliometric analysis to elucidate the current state of advancement and predominant research foci in AI applications within rheumatic diseases. Additionally, it is crucial to identify key contributors and their interrelations in this field. This study aimed to conduct a bibliometric analysis to investigate the current research hotspots and collaborative networks in the application of AI in rheumatic disease in recent years. A comprehensive search was conducted in Web of Science for articles on artificial intelligence in rheumatic diseases, published in SSCI and SCI-EXPANDED until January 1, 2024. Utilizing software tools like VOSviewers and CiteSpace, we analyzed various parameters including publication year, journal, country, institution, and authorship. This analysis extended to examining cited authors, generating reference and citation network graphs, and creating co-citation network and keyword maps. Additionally, research hotspots and trends in this domain were evaluated. As of January 1, 2024, a total of 3508 articles have been published on the application of artificial intelligence (AI) in rheumatic disease, exhibiting a steady rise in both the annual publication frequency and rate. "Scientific Reports" emerged as the leading journal in terms of relevant publications. The United States stood out as the predominant country in terms of the volume of published papers, with the University of California, San Francisco (UCSF) being the most prolific and frequently cited institution. Among authors, Young Ho Lee and Valentina Pedoia were noted for their significant contributions, with Pedoia achieving the highest average citation count per publication. Machine learning emerged as a prominent and central keyword. The trend indicates a growing interest in AI research within rheumatologic diseases, with its role expected to become increasingly pivotal in the field. This study presents a comprehensive summary of research trends and developments in the application of artificial intelligence (AI) in rheumatic diseases. It offers insights into potential collaborations and prospects for future research, clarifying the research frontiers and emerging directions in recent years. The findings of this study serve as a valuable reference for scholars studying rheumatology and immunology.
    Keywords:  Artificial intelligence; Bibliometrics; CiteSpace; Machine learning; Rheumatic diseases; VOS viewers
    DOI:  https://doi.org/10.1007/s10238-024-01453-6
  26. Cureus. 2024 Jul;16(7): e65184
      The autoimmune/inflammatory syndrome induced by adjuvants (ASIA) encompasses various autoimmune conditions triggered by exposure to substances with adjuvant activity. Despite its potential relevance to public health, global scientific production on ASIA syndrome is significantly limited. This knowledge gap underscores the need for a comprehensive bibliometric assessment to understand global research in this field. Therefore, this article aims to conduct a bibliometric analysis to identify and evaluate research trends related to ASIA syndrome worldwide. A Scopus search identified scientific documents published between 2010 and 2022. A total of 2,133 articles meeting inclusion criteria were selected and analyzed for scientific production, authors, and institutions. Two-hundred fifty six documents were analyzed, mostly journal articles with multiple authors. The year with the highest publications was 2023, marking a notable increase since 2021. Italy and Israel had the most documents and citations, correlating with authors Yehuda Shoenfeld (Israel) and Carlo Perricone (Italy). Standout journals are "The Journal of Immunologic Research" and "Lupus." Relevant affiliations include Tel-Aviv University and the National Autonomous University of Mexico. This article identifies and analyzes scientific trends associated with ASIA syndrome. Despite increased publications, this field remains controversial and lacks full acceptance within the medical and scientific community, as evidenced by limited scientific production compared to other pathologies. These findings may motivate researchers to generate impactful publications, contributing to the global knowledge expansion on this syndrome.
    Keywords:  adjuvant-induced autoimmune syndrome (asia); asia syndrome; bibliometrics; scopus; shoenfeld's syndrome
    DOI:  https://doi.org/10.7759/cureus.65184
  27. Indian J Orthop. 2024 Sep;58(9): 1213-1223
       Background: Research and clinical studies on multiligamentous knee injuries (MLKI) have recently gained interest with several clinical studies reported recently. This study aims to identify, visualize, and characterize the MLKI research, to analyze the knowledge structure of MLKI during 2008-2023 and to identify the emerging research trends from a bibliometric perspective.
    Methods: All articles reporting MLKI from 2008 to 2023 were curated from the Scopus database, on 1st January 2024. VOS viewer and Microsoft Excel were used to analyze the publications including the participating countries, authors, organizations, journals and research focus. These data were used to generate visual knowledge maps of the outputs.
    Results: 406 papers on MLKI were published in 115 journals by 483 authors. There has been a slow publication growth in the past 16 years. The United States had more than 50% share in global publications. Knee Surgery Sports Traumatology Arthroscopy, Orthopaedic Journal of Sports Medicine and American Journal of Sports Medicine published the most papers. The three USA institutions, namely Mayo Clinic, Hospital for Special Surgery-New York and Twin Cities Orthopedics contributed the largest number of publications. B.A. Levy (Mayo Clinic, USA) (n = 66) and M.J. Stuart (Mayo Clinic, USA) (n = 63) have registered the highest collaborative links with other authors.
    Conclusions: This study is the first comprehensive bibliometric study to analyze MLKI. The findings shed light on the growth trajectory of publications, the extent of international collaborations, the influence of highly cited articles, and the key countries, institutions, journals, and authors contributing to the field.
    Graphical Abstract:
    Supplementary Information: The online version contains supplementary material available at 10.1007/s43465-024-01149-9.
    Keywords:  Bibliometrics; Knee dislocation; Knee injuries; Knee joint; Ligament; Magnetic Resonance Imaging
    DOI:  https://doi.org/10.1007/s43465-024-01149-9
  28. Heliyon. 2024 Aug 15. 10(15): e35686
       Background: Lung cancer is a highly prevalent cancer on a global scale and its oncogenic process is driven by the accumulation of multiple pathological events. Epigenetics has gained significant recognition in recent years as a crucial contributor to the development of lung cancer. Epigenetics include processes such as DNA methylation, histone modification, chromatin remodeling, and RNA modification. These pathways lead to enduring alterations in genetic phenotypes, which are crucial in the advancement and growth of lung cancer. However, the specific mechanisms and roles of epigenetics in lung cancer still need to be further elucidated.
    Methods: We obtained publications from the Web of Science databases and applied a rigorous search method to filter them. Ultimately, we gathered high-quality publications that had received the highest 100 number of citations. The data were processed and visualized by various bibliometric tools.
    Results: The 100 papers had varying numbers of citations, with the lowest being 491 and the most being 6316. On average, each work received 1119 citations. A total of 1056 co-authors were involved in publishing these papers in 59 journals from 185 institutions in 27 countries. The majority of high-caliber research in the subject of lung cancer epigenetics is conducted in advanced countries, with the United States taking the lead in terms of both the quantity of articles produced and their academic influence. The study of DNA methylation has been a longstanding research priority in the discipline. With the development of next-generation sequencing technology in recent years, research related to non-coding RNA has become a research hotspot. Future research directions may focus more on exploring the mechanisms of action of messenger RNA and circular RNA and developing targeted treatment strategies based on non-coding RNA drugs.
    Conclusion: We analyzed 100 top lung cancer and epigenetics documents through various bibliometric analysis tools. This study provides a concise overview of the findings from prior research, anticipates future research directions, and offers potential avenues for additional investigation.
    Keywords:  Bibliometric analysis; DNA methylation; Epigenetics; Lung cancer; Non-coding RNA
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35686
  29. JMIR Diabetes. 2024 Aug 22. 9 e52196
       BACKGROUND: The widespread use of mobile technologies in health care (mobile health; mHealth) has facilitated disease management, especially for chronic illnesses such as diabetes. mHealth for diabetes is an attractive alternative to reduce costs and overcome geographical and temporal barriers to improve patients' conditions.
    OBJECTIVE: This study aims to reveal the dynamics of scientific publications on mHealth for diabetes to gain insights into who are the most prominent authors, countries, institutions, and journals and what are the most cited documents and current hot spots.
    METHODS: A scientometric analysis based on a competitive technology intelligence methodology was conducted. An innovative 8-step methodology supported by experts was executed considering scientific documents published between 1998 and 2021 in the Science Citation Index Expanded database. Publication language, publication output characteristics, journals, countries and institutions, authors, and most cited and most impactful articles were identified.
    RESULTS: The insights obtained show that a total of 1574 scientific articles were published by 7922 authors from 90 countries, with an average of 15 (SD 38) citations and 6.5 (SD 4.4) authors per article. These documents were published in 491 journals and 92 Web of Science categories. The most productive country was the United States, followed by the United Kingdom, China, Australia, and South Korea, and the top 3 most productive institutions came from the United States, whereas the top 3 most cited articles were published in 2016, 2009, and 2017 and the top 3 most impactful articles were published in 2016 and 2017.
    CONCLUSIONS: This approach provides a comprehensive knowledge panorama of research productivity in mHealth for diabetes, identifying new insights and opportunities for research and development and innovation, including collaboration with other entities, new areas of specialization, and human resource development. The findings obtained are useful for decision-making in policy planning, resource allocation, and identification of research opportunities, benefiting researchers, health professionals, and decision makers in their efforts to make significant contributions to the advancement of diabetes science.
    Keywords:  competitive technology intelligence; diabetes; digital health care; mHealth; mobile health; mobile phone; scientometrics
    DOI:  https://doi.org/10.2196/52196
  30. Tob Induc Dis. 2024 ;22
       INTRODUCTION: The use rate of electronic cigarettes (e-cigarettes) among adolescents is continuously rising globally, posing new challenges to public health and negatively impacting adolescent health. This study employs bibliometric methods to systematically present the current state and evolving trends in global research on adolescent e-cigarette use.
    METHODS: This study uses CiteSpace to conduct a bibliometric analysis of articles related to adolescent e-cigarette use from the Web of Science (WoS) Core Collection database. Firstly, performance analysis and collaboration network analysis were utilized to clarify the basic publication status, main knowledge producers, and knowledge collaboration networks in adolescent e-cigarette use research. Secondly, a co-citation network analysis was performed to visually analyze the disciplinary characteristics and 'hot topics' in this field. Finally, keyword burst detection and clustering techniques were employed to further explain the development trends and frontiers of research on adolescent e-cigarette use.
    RESULTS: A total of 2063 research articles and review articles were included in this study. Research on adolescent e-cigarette use has significantly increased from 2002 to 2024. The United States, the United Kingdom and Canada are the main contributors, with their institutions and researchers playing key roles in the international collaborative network. Current research increasingly adopts interdisciplinary approaches. Keyword co-occurrence and burst identified current research 'hotspots' including vaping, substance use, public policy, prevention, advertising, and cessation. Co-citation cluster analysis revealed promising research areas such as attractiveness, environment and health, accessibility and smoking behavior, and mental health.
    CONCLUSIONS: Through data mining and visualization techniques, this study provides a comprehensive bibliometric analysis of published work on e-cigarettes and adolescence. The results of this work offer references for researchers in future investigations.
    Keywords:  adolescents; bibliometric analysis; electronic cigarette
    DOI:  https://doi.org/10.18332/tid/191761
  31. Front Psychol. 2024 ;15 1414528
       Background: Malignant tumors of the digestive system pose a serious threat to human health due to their highly malignant nature. Depression, as the most common psychiatric symptom of digestive system tumors, has attracted much attention regarding its potential relationship with these tumors. A thorough investigation into the connection between digestive system tumors and depression is extremely important for strengthening patients' quality of life and treatment outcomes.
    Methods: From 2014 to 2023, we conducted a literature search using specific keywords in the Web of Science Core Collection (WoSCC) and performed visual analysis of the selected literature using Microsoft Excel, CiteSpace, and VOSviewer software. In this study, we analyzed countries, institutions, authors, journals, and keywords.
    Results: A total of 384 research articles on the relationship between digestive system tumors and depression were identified. The number of publications showed a gradual increase over time. In terms of disciplinary distribution, Oncology, Health Care Sciences Services, and Medicine General Internal ranked top in terms of publication volume. In terms of geographical distribution, China and the United States were the countries contributing the most publications. Additionally, Maastricht University contributed the most publications. Regarding authors, Beekman, Aartjan T.F. and Dekker, Joost had the highest number of publications, while Zigmond, A.S. had the most citations. It is worth mentioning that Supportive Care in Cancer was the journal with the most publications in this field. In terms of keyword analysis, research mainly focused on mechanisms and treatment strategies related to the relationship between digestive system tumors and depression.
    Conclusion: The relationship between digestive system tumors and depression has become a new research hotspot in recent years, offering new directions for future research. This research reveals novel perspectives on comprehending the connection between the two, which can guide future research and practice.
    Keywords:  Web of Science; bibliometrics; depression; digestive system tumors; visualization
    DOI:  https://doi.org/10.3389/fpsyg.2024.1414528
  32. Front Psychiatry. 2024 ;15 1431215
       Background: Rising anxiety and depression in primary school students adversely affect their development and academics, burdening families and schools. This trend necessitates urgent, focused research within this young demographic. This alarming trend calls for a systematic bibliometric analysis to develop effective preventative and remedial strategies.
    Objectives: This study aims to identify and analyze the prevailing research hotspots and emerging trends concerning anxiety and depression in primary school students, thereby furnishing a foundational reference for future academic endeavors in this area.
    Methods: This study uses the Web of Science (WOS) Core Collection database as the data source, focusing on literature published between 2013 and 2023 concerning anxiety and depression in primary school students. An initial search identified 1852 articles, which were then manually screened to exclude duplicates, conferences, announcements, and unrelated literature, resulting in 1791 relevant articles. The analysis, executed on December 31, 2023, employed CiteSpace and Vosviewer tools to assess various bibliometric indicators including authorship, country, institutional affiliations, publication trends, keyword frequency, and citation analysis.
    Results: The analysis revealed a corpus of 1,791 English-language articles, with a discernible upward trend in publications over the decade. The USA and China were the leading countries in this field, with 482and 272 papers, respectively. The research predominantly addresses the etiological factors of anxiety and depression, various intervention strategies, and the comorbidities associated with these conditions in the target population. Key research focuses have been identified in areas such as suicidal thoughts, bullying in schools, the impact of COVID-19, mindfulness interventions, and anxiety related to mathematics. Future research is projected to increasingly focus on the effects of mathematics anxiety on the psychological and behavioral outcomes in students.
    Conclusion: This study provides a critical visual and analytical overview of the key research areas and trends in the field of anxiety and depression among primary school students. It underscores the necessity of concentrating on the underlying causes and potential interventions. Such focused research is imperative for mitigating the mental health challenges faced by young students and enhancing their educational and developmental outcomes.
    Keywords:  CiteSpace; VOSviewer; anxiety; bibliometrics; depression; primary school students
    DOI:  https://doi.org/10.3389/fpsyt.2024.1431215
  33. Orthopedics. 2024 Aug 19. 1-5
       BACKGROUND: Altmetric Attention Score (AAS) captures online attention received by a research article in addition to traditional bibliometrics. We present a comprehensive bibliometric analysis of high AAS articles and identify predictors of AAS in orthopedics.
    MATERIALS AND METHODS: The top 30 articles with highest AAS were selected from orthopedic journals using the Dimensions App. Multilevel mixed-effects linear regression was used to address clustering in articles from the same journal, with journals as the leveling variable.
    RESULTS: A total of 750 articles from 25 journals were included. In the final multivariable model, the funding source (none, industry, government, foundation, university, or multiple), findings (positive, negative, neutral, or not applicable), and the journal's impact factor were significant at P<.05.
    CONCLUSION: Predictors of AAS are similar to predictors of traditional bibliometrics. Future studies need prospective dynamic data to further elucidate the AAS. [Orthopedics. 20XX;4X(X):XXX-XXX.].
    DOI:  https://doi.org/10.3928/01477447-20240809-03
  34. Orthop J Sports Med. 2024 Aug;12(8): 23259671241260049
       Background: Citation analysis reflects the influence a work has on a field of research and can be used to identify "classic" works and their qualities in medical specialties. By analyzing the characteristics of these works, we intended to determine what qualities make for a highly cited work in pediatric orthopaedic sports medicine.
    Purpose: To identify the top 25 most cited articles in the field of pediatric orthopaedic sports medicine.
    Study Design: Cross-sectional study.
    Methods: The Science Citation Index Expanded feature within the Web of Science database was searched using a Boolean string, generating 2008 pediatric orthopaedic sports medicine articles arranged by number of citations. The top 25 most cited articles were reviewed for authors, year of publication, source journal, country of origin, region of origin, diagnosis or condition of focus, and level of evidence (LOE).
    Results: Most of the articles were published in the 2000s (range, 1992-2016). The mean number of citations was 166 (range, 119-329), and the mean citation density was 13.25 (range, 4.25-29.57). There were 18 of 25 studies performed in the United States. A plurality of the articles were published in the American Journal of Sports Medicine. The LOE ranged from 2 to 4, with the most common being level 2 (11/25). Anterior cruciate ligament (ACL) injury management (14/25) and epidemiological studies on the incidence of various sports injuries (6/25) were the most represented topics of study. Since the 1990s, the mean citation density for articles related to ACL injuries in young athletes and the epidemiology of sports injuries has been increasing.
    Conclusion: This evaluation demonstrated that ACL injuries and the epidemiology of sports injuries had the highest citation density of the most influential studies in pediatric orthopaedic sports medicine. We identified attributes such as country of publication, journal of publication, and LOE that make for a highly cited pediatric orthopaedic sports medicine article. Overall, citation density in pediatric sports medicine is increasing. Nonetheless, the most represented LOE in the most cited works is level 2, with no level 1 studies being represented in the top 25. In terms of both topics and LOE, this study allows surgeons to identify deficiencies in the existing literature and meaningfully design future studies to improve on these.
    Keywords:  citation density; classic works; most cited; pediatric sports medicine
    DOI:  https://doi.org/10.1177/23259671241260049
  35. Front Neurol. 2024 ;15 1420402
       Objective: To use bibliometric methods to analyze the research hotspots and future development trends regarding the application of mesenchymal stem cells in peripheral nerve injury and regeneration.
    Methods: Articles published from January 1, 2013, to December 31, 2023, were meticulously screened using the MeSH terms: TS = ("Mesenchymal stem cells" AND "Peripheral nerve injury") OR TS = ("Mesenchymal stem cells" AND "Peripheral nerve regeneration") within the Web of Science database. The compiled data was then subjected to in-depth analysis with the aid of VOSviewer and Cite Space software, which facilitated the identification of the most productive countries, organizations, authors, and the predominant keywords prevalent within this research domain.
    Results: An extensive search of the Web of Science database yielded 350 relevant publications. These scholarly works were authored by 2,049 collaborative researchers representing 41 countries and affiliated with 585 diverse academic and research institutions. The findings from this research were disseminated across 167 various journals, and the publications collectively cited 21,064 references from 3,339 distinct journals.
    Conclusion: Over the past decade, there has been a consistent upward trajectory in the number of publications and citations pertaining to the use of mesenchymal stem cells in the realm of peripheral nerve injury and regeneration. The domain of stem cell therapy for nerve injury has emerged as a prime focus of research, with mesenchymal stem cell therapy taking center stage due to its considerable promise in the treatment of nerve injuries. This therapeutic approach holds the potential to significantly enhance treatment options and rehabilitation prospects for patients suffering from such injuries.
    Keywords:  Schwann cells; bibliometrics; mesenchymal stem cells; neural regeneration; peripheral nerve injury
    DOI:  https://doi.org/10.3389/fneur.2024.1420402
  36. Heliyon. 2024 Aug 15. 10(15): e35471
      This study analyzes 1643 documents related to skiing from 1974 to 2023 using the Web of Science Core Collection database, employing CiteSpace and VOSviewer for quantitative analysis. Findings reveal a growing literature output, with the past five years contributing to 36.2 % of publications. Norway leads in total publications and collaboration intensity, with the University of Salzburg and the Norwegian University of Science and Technology as prominent institutions. The research spans a wide range of disciplines such as Sport Sciences, Physiology, etc., and interdisciplinary intersections with engineering, computer science, etc. have become a future research trend. The research focuses on the analysis of skiers' sports performance, the analysis of skiing-induced sports injuries, the biomechanical analysis of skiers' postures, and the analysis of skiing-induced respiratory diseases. The study highlights the evolution of research focus from skiing injuries to injury prevention and sports performance enhancement. This comprehensive overview aids scholars in understanding skiing research hotspots and future trends efficiently.
    Keywords:  Bibliometrics; CiteSpace; Development trend; Skiing; VOSviewer
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35471
  37. Heliyon. 2024 Aug 15. 10(15): e35088
      Luteal phase defect (LPD) is a common female reproductive endocrine defect,which is associated not only with certain diseases but also with the menstrual cycle and fertility in women. With the development of assisted reproductive technology (ART) in recent years, the incidence of luteal phase defect is high among patients using assisted reproductive technology. The aim of this study was to evaluate worldwide research on luteal phase defects using bibliometric analysis. A total of 631 documents related to the study of luteal phase defect were identified over the last 52 years. The current status and trend of globalization can be comprehended by analyzing the annual number of publications, institutions, authors, countries and regions of corresponding authors, journals, influential luteal phase defect publications (which were highly cited), highly cited references in luteal phase defect publications (cocitation analysis) and keywords. The study results provide a comprehensive overview of the development of scientific literature and are of great significance for the future development of the field,especially infertility and early pregnancy loss.
    Keywords:  Bibliometric analysis; Hotspots; Luteal phase defect; Research trends; VOSviewer; Web of science
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35088
  38. J Int Adv Otol. 2024 May 23. 20(3): 261-271
      This article evaluated the current status and focus areas in benign paroxysmal positional vertigo (BPPV) research in the world and to predict the direction of future research. Web of Science Core Collection were searched from January 1, 2002, to December 31, 2021. Bibliometric and statistical analysis were conducted to generate the basic information of the publications. A total of 1255 publications were identified, with an increasing trend in the number of annual number of publications from 2019 to 2021. Otology & Neurotology was the most productive journal. Kim J, Kim C, and Lee J from South Korea were the top 3 productive authors. Seoul National University is the most influential institution. The top 5 cited burst keywords include recurrence, osteoporosis, bone mineral density, vitamin D deficiency, and BPPV. The annual number of publications would continue to grow. The future research of BPPV will concentrate on osteoporosis and recurrence.
    DOI:  https://doi.org/10.5152/iao.2024.231290
  39. Anaesthesiol Intensive Ther. 2024 ;pii: 54444. [Epub ahead of print]56(2): 129-140
       INTRODUCTION: In the era of problems with resistant bacteria strains, pharmacokinetic (PK) modelling offers ways to optimise antibiotic therapy and minimise the risk of resistance development. This bibliometric study aimed to investigate trends in PK modelling stu-dies. The goal was to provide researchers with comprehensive insight and identify future needs.
    MATERIAL AND METHODS: We used Bibliometrix, VOSviewer, and CiteSpace to analyse Web of Science articles on antibiotic PK modelling from 1983 to March 2023.
    RESULTS: We analysed 968 papers following the inclusion criteria and built a keywords co-occurrence map and timeline. The average annual growth rate of subject-related publications was 35.56% between 1983 and 2022, maintaining a continuous upward trend. Roberts J.A., Lipman J., and Wallis S.C. are the three most productive and impactful authors (82, 57, 34 articles, and h-index of 30, 25, 15, respectively). The United States leads in this field of research (29.13% of papers). The most relevant affiliations are the University of Queensland, Royal Brisbane and Women's Hospital, and Monash University. The top three most productive and impactful journals are Antimicrobial Agents and Chemotherapy, Journal of Antimicrobial Chemotherapy, and International Journal of Antimicrobial Agents (181, 83, 47 articles and h-index of 42, 30, 18, respectively). Most articles by keyword clustered on meropenem, vancomycin, and amikacin. Moreover, therapeutic drug monitoring, resistance, antibiotic dosing, target attainment, the intensive care unit, and paediatrics are the most trending aspects.
    CONCLUSIONS: Given the results of this study, we expect to see a steady increase in interest in exploiting the potential of PK modelling for optimising antibiotic therapy.
    Keywords:   Monte Carlo simulations; PK modelling; antibiotic therapy; bacterial resistance; pharmacometrics; bibliometrics
    DOI:  https://doi.org/10.5114/ait.2024.141332
  40. Asian J Surg. 2024 Aug 15. pii: S1015-9584(24)01672-5. [Epub ahead of print]
      
    Keywords:  Bibliometric analysis; Diabetic retinopathy; Emotional distress; Endocrine disease
    DOI:  https://doi.org/10.1016/j.asjsur.2024.07.299
  41. Heliyon. 2024 Aug 15. 10(15): e35499
       Aim of the study: To analyze the progress in Mongolian medicine and medicinal materials and to highlight its development process, emerging trends, and hotspots.
    Materials and methods: Papers on Mongolian medicine and medicinal materials from January 2000 to May 2022 were retrieved from the China National Knowledge Infrastructure (CNKI) database. Using the collaboration network analysis of CiteSpace V and VOSviewer software, the cooperation among individuals and institutions in the field of scientific research was analyzed. The functions of frequency analysis, cluster analysis, and burst analysis were employed to conduct bibliometric analysis on research hotspots and trends in the field of Mongolian medicine research. Furthermore, the data visualization function was utilized to clearly display data trends and changes.
    Results: A total of 8362 papers on Mongolian medicine medicinal materials from CNKI were identified and analyzed.The research on Mongolian medicine has gone through three stages: the initial stage, the exploratory stage, and the developmental stage. The top two institutions in the number of papers are Inner Mongolia Medical University and Inner Mongolia University for Nationalities. Bagenna from Inner Mongolia Medical University is the author with the most papers. "clinical efficacy", "clinical research", and "quality standards" were the most frequently used keywords. Research in the field of Mongolian medicine has focused on several diseases, including skeletal system disorders, cardiovascular diseases, and digestive system disorders.
    Conclusion: Since 2000, there have been growing attention and efforts made in the field of Mongolian medicine and medicinal materials. The research in the field of Mongolian medicine had undergone three stages, namely the initial stage, the exploratory stage, and the developmental stage. The focus shifted from basic research such as the analysis of medicinal ingredients in Mongolian herbs to the application-oriented directions of traditional treatment techniques and advantageous diseases in Mongolian medicine. To make breakthroughs in this field, further research is needed to improve the persuasiveness and authority of Mongolian medicine and medicinal materials in terms of mechanism, standardization, and safety, to promote the development of Mongolian medicine and medicinal materials.
    Keywords:  Bibliometrics; Citespace; Mongolian medicine and medicinal materials; VOSviewer; Visualization analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35499
  42. J Robot Surg. 2024 Aug 17. 18(1): 324
      Simulation-based robotic surgery training may help surgeons gain operative skills and experience in the simulation environment. This bibliometric analysis examined the development of simulation-based training for robotic surgical education. Articles pertaining to robotic surgical simulation training that were included in the Web of Science Core Collection up to April 25, 2024, were included. The temporal patterns in published paper numbers were evaluated using Microsoft Excel software, and the data regarding co-authorship and keyword co-occurrence were analyzed and visualized using the VOSviewer and SCImago Graphica tools. A total of 594 papers on simulation-based training for robotic surgical education were evaluated in this study. The United States and United Kingdom were the leading contributors in this field. The most published authors were Professor Ahmed Kamran (23 publications) and Prokar Dasgupta (22 publications). The highest number of papers was published in the journal titled "Surgical Endoscopy and Other Interventional Techniques." The most common keywords were "virtual reality," "curriculum," "robotic surgery simulator," "assessment," and "learning curve." Our study offers a detailed overview of international research on simulation-based training for robotic surgical education, including the publishing countries, institutions, authors, journals, and research hotspots. It also methodically summarizes the state of knowledge in the area, and provides definite directions and concepts for further in-depth analysis.
    Keywords:  Bibliometric; Robotics; Simulation; Training; Visualization
    DOI:  https://doi.org/10.1007/s11701-024-02076-5
  43. Heliyon. 2024 Aug 15. 10(15): e35767
       Background: Africa has a high double burden of infectious and non-communicable diseases underscoring the critical need for robust scientific research. However, it is also associated with low scientific research productivity. Mozambique, which gained independence in 1975, serves as a poignant example. However, there remains a notable scarcity of evidence evaluating the country's trajectory in scientific and academic development. This study aims to evaluate 43 years of health-related scientific knowledge production through bibliometric analysis, focusing on key indicators. Additionally, it seeks to characterize the higher education institutions within the country.
    Methods: The data was retrieved from the Web of Science Core Collection using an advanced search tool with Boolean research strategies, covering the period from 1976 to 2022 for all PALOP and 1976 to 2019 for Mozambique. To map Mozambican higher institutions, information was sourced from the Ministry of Science Technology and Higher Education database. Descriptive statistics were employed to summarize the findings, while the VOSviewer program version 1.6.19 was utilized to visualize distance-based bibliometric networks, focusing on co-authorship among institutions and keyword co-occurrence.
    Results: Portuguese-speaking African countries (PALOP) contribute 2.5 % (10,933 out of 442,309) to Africa's total scientific output, with Mozambique leading at 63.6 % (6,951 publications) followed by Angola at 16.6 % (1,811 publications). All PALOP countries experienced decreased scientific productivity during the third year of the COVID-19 pandemic. In Mozambique, over 70 % (1,710 out of 2,380) of health-related publications from 2011 to 2019 were concentrated in this period. Key journals for health sciences include PLOS ONE, Malaria Journal, and Tropical Medicine & International Health, focusing on HIV, malaria, and tuberculosis. Higher education institutions in Mozambique show regional disparities, with 67.9 % in the South and only 8.9 % in the North, indicating significant inequality in their distribution across the country.
    Conclusion: This study highlights Mozambique's significant progress in health research productivity over 43 years, establishing it as a leader among PALOP countries. The substantial increase in publications, particularly after 2008, underscores the nation's growing research capacity and commitment to addressing critical health challenges such as HIV, malaria, and tuberculosis. However, regional disparities in higher education access and limited research contributions from private universities remain high in Mozambique.
    Keywords:  Bibliometric; Health science research; Higher education institutions; Mozambique; PALOP; Productivity
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35767
  44. Fa Yi Xue Za Zhi. 2024 Jun 25. pii: 1004-5619(2024)03-0245-09. [Epub ahead of print]40(3): 245-253
       OBJECTIVES: To describe the current state of research and future research hotspots through a metrological analysis of the literature in the field of forensic anthropological remains identification research.
    METHODS: The data retrieved and extracted from the Web of Science Core Collection (WoSCC), the core database of the Web of Science information service platform (hereinafter referred to as "WoS"), was used to analyze the trends and topic changes in research on forensic identification of human remains from 1991 to 2022. Network visualisation of publication trends, countries (regions), institutions, authors and topics related to the identification of remains in forensic anthropology was analysed using python 3.9.2 and Gephi 0.10.
    RESULTS: A total of 873 papers written in English in the field of forensic anthropological remains identification research were obtained. The journal with the largest number of publications was Forensic Science International (164 articles). The country (region) with the largest number of published papers was China (90 articles). Katholieke Univ Leuven (Netherlands, 21 articles) was the institution with the largest number of publications. Topic analysis revealed that the focus of forensic anthropological remains identification research was sex estimation and age estimation, and the most commonly studied remains were teeth.
    CONCLUSIONS: The volume of publications in the field of forensic anthropological remains identification research has a distinct phasing. However, the scope of both international and domestic collaborations remains limited. Traditionally, human remains identification has primarily relied on key areas such as the pelvis, skull, and teeth. Looking ahead, future research will likely focus on the more accurate and efficient identification of multiple skeletal remains through the use of machine learning and deep learning techniques.
    Keywords:  Gephi; Web of Science; betweenness centrality; bibliometrics; eigenvector centrality; forensic anthropological; network visualization; remains
    DOI:  https://doi.org/10.12116/j.issn.1004-5619.2023.430803
  45. Int J Ophthalmol. 2024 ;17(8): 1501-1509
       AIM: To analyze the changes in scientific output relating to Leber congenital amaurosis (LCA) and forecast the study trends in this field.
    METHODS: All of the publications in the field of LCA from 2002 to 2022 were collected from Web of Science (WOS) database. We analyzed the quantity (number of publications), quality (citation and H-index) and development trends (relative research interest, RRI) of published LCA research over the last two decades. Moreover, VOSviewer software was applied to define the co-occurrence network of keywords in this field.
    RESULTS: A total of 2158 publications were ultimately examined. We found that the focus on LCA kept rising and peaked in 2015 and 2018, which is consistent with the development trend of gene therapy. The USA has contributed most to this field with 1162 publications, 56 674 citations and the highest H-index value (116). The keywords analysis was divided into five clusters to show the hotspots in the field of LCA, namely mechanism-related, genotype-related, local phenotype-related, system phenotype-related, and therapy-related. We also identified gene therapy and anti-retinal degeneration therapy as a major focus in recent years.
    CONCLUSION: Our study illustrates historical research process and future development trends in LCA field. This may help to guide the orientation for further clinical diagnosis, treatment and scientific research.
    Keywords:  Leber congenital amaurosis; VOSviewer; bibliometrics; gene therapy; hotpots
    DOI:  https://doi.org/10.18240/ijo.2024.08.17
  46. Heliyon. 2024 Aug 15. 10(15): e35185
       Background: Surgical pain affects postoperative sleep quality, and they jointly form a vicious cycle of mutual influence. The cycle of postoperative pain and sleep disorders could lead to delirium, cardiovascular disease, and hyperalgesia, which significantly affect patients' postoperative recovery. Thus, exploring this phenomenon is of great importance for surgical patients, and warrants further investigation.
    Objective: By employing bibliometric methods, this study systematically analyzes the publications on postoperative pain-sleep disorders, identifies research trends and field dynamics, and ultimately provides insights for further progress in this research area.
    Methods: In this study, we searched the Web of Science database for studies on postoperative pain and sleep disorders from 2013 to 2023, and analyzed the number of publications, journals, authors, institutions, country regions, and keywords by utilizing CiteSpace, VOSviewer, and Bibliometrix.
    Results: The 1894 retrieved publications showed a trend of increasing number of publications and correlations between postoperative pain and sleep disorders from 2013 to 2023. The top countries for publications included the USA, China, etc., establishing a global collaborative network centered around the USA, China, and Europe. The top institutions for publications included University of California System, Harvard University, etc. The top authors include Christine Miaskowski, Steven M. Paul, Qiuling Shi, etc. These publications involved multiple disciplines including surgery, neurology, and anesthesiology, and various research funds including NIH, HHS, NSFC, etc. The top journals for publications included the European Archives of Oto-Rhino-Laryngology, etc. Keywords that appear most frequently in this field include "pain", "surgery", "quality of life", "sleep", "depression", and "outcomes". The thematic map indicated that the hot topics in this area include obstructive sleep apnea, tonsillectomy, children, pain, quality of life, and sleep. The undeveloped topics with research potential included postoperative pain, analgesia and dexmedetomidine, breast cancer, fatigue, and lung cancer.
    Conclusion: The increased number of publications and correlations between postoperative pain and sleep disorders, and the collaborative network across the USA, China, and Europe indicate a growing global interest in this area. This study also provides valuable insights into the trend of hot topics and frontiers and shows that this is an evolving and dynamic research area.
    Keywords:  Bibliometric analysis; Cycle; Postoperative pain; Recovery; Sleep disorders
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35185
  47. Life Sci. 2024 Aug 19. pii: S0024-3205(24)00590-3. [Epub ahead of print] 123000
       BACKGROUND: Lung ischemia-reperfusion injury (LIRI) poses a significant challenge in various clinical scenarios. Despite extensive research on the pathogenesis and potential treatments of LIRI, there is a notable absence of bibliometric analysis.
    MATERIALS AND METHODS: We summarized the results of LIRI research through two searches on the Web of Science, covering data from 1979 to 2023 with topic words "lung" and "reperfusion injury". The collected data were analyzed and visualized based on country, author(s), and keywords by bibliometric software. The keyword "programmed cell death" was further added to explore the hotspot of the LIRI research field.
    RESULTS: The initial analysis of 1648 research articles showed a total of 40 countries and 7031 researchers were involved in the publications, with America being the most productive country in the research field of LIRI. Keyword analysis revealed that the evolving focus of LIRI research has progressively transitioned from, lung transplantation, primary graft dysfunction, inflammation, oxidative stress, and ex vivo lung perfusion to cell death. Subsequently, 212 publications specifically addressing programmed cell death (PCD) in LIRI were identified, which clarified the recent hotspot of the LIRI field.
    CONCLUSION: With closer international cooperation and increasing research scale, the LIRI research focused mainly on the pathogenesis and potential therapeutic interventions for LIRI. PCD in LIRI is becoming a trending topic and will continue to be a hotspot in this field. Our study may offer valuable guidance for future research endeavors concerning LIRI.
    Keywords:  Bibliometric analysis; Lung ischemia-reperfusion injury; Lung transplantation; Programmed cell death; Research progression
    DOI:  https://doi.org/10.1016/j.lfs.2024.123000
  48. Medicine (Baltimore). 2024 Aug 16. 103(33): e39370
      With the rapid development of emerging information technologies such as artificial intelligence, cloud computing, and the Internet of Things, the world has entered the era of big data. In the face of growing medical big data, research on the privacy protection of personal information has attracted more and more attention, but few studies have analyzed and forecasted the research hotspots and future development trends on the privacy protection. Presently, to systematically and comprehensively summarize the relevant privacy protection literature in the context of big healthcare data, a bibliometric analysis was conducted to clarify the spatial and temporal distribution and research hotspots of privacy protection using the information visualization software CiteSpace. The literature papers related to privacy protection in the Web of Science were collected from 2012 to 2023. Through analysis of the time, author and countries distribution of relevant publications, we found that after 2013, research on the privacy protection has received increasing attention and the core institution of privacy protection research is the university, but the countries show weak cooperation. Additionally, keywords like privacy, big data, internet, challenge, care, and information have high centralities and frequency, indicating the research hotspots and research trends in the field of the privacy protection. All the findings will provide a comprehensive privacy protection research knowledge structure for scholars in the field of privacy protection research under the background of health big data, which can help them quickly grasp the research hotspots and choose future research projects.
    DOI:  https://doi.org/10.1097/MD.0000000000039370
  49. Heliyon. 2024 Aug 15. 10(15): e34933
       Research purpose: This study aims to outline the fundamental status of the German academic community's research in the field of renewable energy and to foster collaboration between China and Germany in this area.
    Research methods: This study examines documents published by German scholars from 2008 to 2023, which are part of the "Web of Science (WOS) Core Collection" database and related to renewable energy issues, using the bibliometric visualization tool CiteSpace 6.2.R6.
    Research conclusions: The study examines the co-occurrence and burst of keywords, changes in publication volume, international collaboration networks, research institution collaboration networks, and researcher collaboration networks. It concluded that: (1) German academic research in the field of renewable energy can be divided into three phases: nascent (2008-2014), surge (2015-2021), and decline (2022-2023). (2) The Helmholtz Association and Reinhard Madlener, among other prominent institutions and academicians, are responsible for the close cooperation among personnel and institutions, the significant leading effect, and the emphasis on cutting-edge topics. Research in this field notably focuses on cutting-edge issues like life cycle assessment and developing countries. The study observes a transition in research concentration from macro to micro perspectives. In the context of a global collective response to climate change, the analysis of the German academic community's overall situation will enhance the collaboration between the two countries in the field of renewable energy research.
    Keywords:  Bibliometric analysis; CiteSpace; Germany; New energy; Renewable energy; Visualization map
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e34933
  50. Heliyon. 2024 Aug 15. 10(15): e35627
       Background: Simulation-based medical education (SBME) is a widely used method in medical education. This study aims to analyze publications on SBME in terms of countries, institutions, journals, authors, and keyword co-occurrence, as well as to identify trends in SBME research.
    Methods: We retrieved the Publications on SBME from the Web of Science Core Collection (WoSCC) database from its inception to January 27, 2024. Microsoft Excel 2019, CiteSpace, and VOSviewer were used to identify the distribution of countries, journals, and authors, as well as to determine the research hotspots.
    Results: We retrieved a total of 11272 publications from WoSCC. The number of documents published in 2022 was the highest in the last few decades. The USA, the UK, and Canada were three key contributors to this field. The University of Toronto, Stanford University, and Harvard Medical School were the top major institutions with a larger number of publications. Konge, Lars was the most productive author, while McGaghie, William C was the highest cited author. BMC Medical Education has the highest number of publications among journals. The foundational themes of SBME are "Patient simulation," "extending reality," and "surgical skills."
    Conclusions: SBME has attracted considerable attention in medical education. The research hotspot is gradually shifting from traditional simulations with real people or mannequins to virtual, digitally-based simulations and online education. Further studies will be conducted to elucidate the mechanisms of SBME. The utilization of SBME will be more rationalized.
    Keywords:  Bibliometrics; Clinical training; Medical education; Simulation; Visualization analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35627
  51. World J Clin Cases. 2024 Aug 16. 12(23): 5382-5403
       BACKGROUND: Intracranial aneurysms (IAs) pose significant health risks, attributable to their potential for sudden rupture, which can result in severe outcomes such as stroke and death. Despite extensive research, the variability of aneurysm behavior, with some remaining stable for years while others rupture unexpectedly, remains poorly understood.
    AIM: To employ bibliometric analysis to map the research landscape concerning risk factors associated with IAs rupture.
    METHODS: A systematic literature review of publications from 2004 to 2023 was conducted, analyzing 3804 documents from the Web of Science Core Collection database, with a focus on full-text articles and reviews in English. The analysis encompassed citation and co-citation networks, keyword bursts, and temporal trends to delineate the evolution of research themes and collaboration patterns. Advanced software tools, CiteSpace and VOSviewer, were utilized for comprehensive data visualization and trend analysis.
    RESULTS: Analysis uncovered a total of 3804 publications on IA rupture risk factors between 2006 and 2023. Research interest surged after 2013, peaking in 2023. The United States led with 28.97% of publications, garnering 37706 citations. Notable United States-China collaborations were observed. Capital Medical University produced 184 publications, while Utrecht University boasted a citation average of 69.62 per publication. "World Neurosurgery" published the most papers, contrasting with "Stroke", the most cited journal. The PHASES score from "Lancet Neurology" emerged as a vital rupture risk prediction tool. Early research favored endovascular therapy, transitioning to magnetic resonance imaging and flow diverters. "Subarachnoid hemorrhage" stood out as a recurrent keyword.
    CONCLUSION: This study assesses global IA research trends and highlights crucial gaps, guiding future investigations to improve preventive and therapeutic approaches.
    Keywords:  Bibliometric; CiteSpace; Intracranial aneurysm; Risk factor; VOSviewer
    DOI:  https://doi.org/10.12998/wjcc.v12.i23.5382
  52. Heliyon. 2024 Aug 15. 10(15): e35067
       Background: In the study of atrial fibrillation (AF), a prevalent cardiac arrhythmia, the utilization of artificial intelligence (AI) in diagnostic and therapeutic strategies holds the potential to address existing limitations. This research employs bibliometrics to objectively investigate research hotspots, development trends, and existing issues in the application of AI within the AF field, aiming to provide targeted recommendations for relevant researchers.
    Methods: Relevant publications on the application of AI in AF field were retrieved from the Web of Science Core Collection (WoSCC) database from 2013 to 2023. The bibliometric analysis was conducted by the R (4.2.2) "bibliometrix" package and VOSviewer(1.6.19).
    Results: Analysis of 912 publications reveals that the field of AI in AF is currently experiencing rapid development. The United States, China, and the United Kingdom have made outstanding contributions to this field. Acharya UR is a notable contributor and pioneer in the area. The following topics have been elucidated: AI's application in managing the risk of AF complications is a hot mature topic; AI-electrocardiograph for AF diagnosis and AI-assisted catheter ablation surgery are the emerging and booming topics; smart wearables for real-time AF monitoring and AI for individualized AF medication are niche and well-developed topics.
    Conclusion: This study offers comprehensive analysis of the origin, current status, and future trends of AI applications in AF, aiming to advance the development of the field.
    Keywords:  Artificial intelligence; Atrial fibrillation; Bibliometric analysis; Bibliometrix; Machine learning; VOSviewer
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35067
  53. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2392961
      Dendritic cells, which are crucial for inducing T-cell responses, are pivotal in current immunotherapy strategies aiming to replenish depleted T cells within the tumor microenvironment to combat tumors. Consequently, dendritic cell vaccine-based cancer therapies have garnered significant attention. Through bibliometric analysis, we examined research trends in this field. We searched the Web of Science core database and identified 16,476 articles on dendritic cell-based vaccines published from January 1, 2009, to December 30, 2023. The United States leads in this research domain, with Emory University being a prominent collaborator. The Journal of Immunology is the primary publication outlet, and Banchereau, J emerges as the most influential author. Recent hot keywords include nanoparticle, delivery, cancer vaccine, and clinical trial, indicating that cancer immunotherapy research, especially dendritic cell-based vaccines, is poised to become a future trend and hotspot.
    Keywords:  Bibliometric analysis; CiteSpace; VOSviewer; dendritic cell-based vaccines; hot topic
    DOI:  https://doi.org/10.1080/21645515.2024.2392961
  54. Front Oncol. 2024 ;14 1429885
       Background: Implant-based breast reconstruction (IBR), following mastectomy, significantly impacts patients' quality of life (QoL), necessitating accurate measurement through psychometrically robust patient-reported outcome measure (PROM) tools. This bibliometric analysis aims to discern trends, identify gaps, and evaluate the use of such tools in the IBR literature.
    Methods: The 100 most cited publications regarding QoL in implant-based reconstruction were identified on Web of Science, across all available journal years (from 1977 to 2024) on 10 March 2024. Study details, including the citation count, main content focus, outcome measures, and usage of psychological questionnaires, were extracted and tabulated from each publication. The Oxford Centre for Evidence-Based Medicine (OCEBM) levels of evidence (LOE) of each study were assessed.
    Results: The 100 most cited publications on QoL in implant-based reconstruction were identified, encompassing 64,192 patients and 28,114 reconstructed breasts. Citations per publication ranged from 62 to 457 (mean, 124.95 ± 73.05), with the highest-cited study being authored by Al-Ghazal (n = 457). The vast majority of publications were LOE II (n = 52), representative of prospective cohort studies, systematic reviews of non-randomised studies, and systematic review and meta-analysis. The number of publications for LOE V, IV, III, and I was 0, 7, 41, and 0, respectively. The main content focus was "quality of life" in 83 publications, with significant utilisation of the BREAST-Q questionnaire. A total of 80 publications used validated questionnaires with psychometric development.
    Conclusions: This analysis demonstrates that the research methodologies within IBR mostly consist of moderate-quality publications; however, notably, there was a lack of LOE I studies, underscoring a gap in high-quality research within the field. Moreover, only 62/100 used validated PROM tools. Future IBR research studies should be focussed on most robust methodologies, incorporating validated PROM tools, to optimise shared-decision making and informed consent.
    Keywords:  BREAST-Q; Web of Science; breast implants; breast reconstruction; patient satisfaction; patient-reported outcome; psychological wellbeing; quality of life
    DOI:  https://doi.org/10.3389/fonc.2024.1429885
  55. Heliyon. 2024 Aug 15. 10(15): e34720
       Background: The global incidence of neurological diseases has been on the rise, creating an urgent need for a validated marker. Neurofilament Light Chain (NfL) holds promise as such a marker and has garnered significant attention in the field of neurological diseases over the past decades.
    Methods: Corresponding articles from 2013 to 2023 were collected from the Web of Science database, and data were analyzed by CiteSpace and VOSviewer software.
    Results: A total of 1350 articles were collected from 296 countries/regions, involving 7246 research organizations. Since 2013, among the top ten institutions and authors with the highest number of published papers, the most are from the US and the UK. The United States leads in the number of published papers, but England holds a more momentous position, because it has higher IF. Henrik Zetterberg is the most influential scholar in the field.
    Conclusions: The output of papers mainly relies on researchers from developed countries, and scholars from the United States and England have contributed the largest number of papers. Until now, the importance of NfL in neurological diseases has attracted global attention. In addition, NfL contributes to the potential diagnosis of various neurological disorders and can be used to improve the accuracy of differential diagnosis and prognostic assessment as well as predict the response to treatments. More and more in-depth studies are highly needed in the future.
    Keywords:  Bibliometrics; Biomarkers; Neurologic diseases; NfL; Visualization
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e34720
  56. J Oral Pathol Med. 2024 Aug 21.
       BACKGROUND: Salivary biomarkers play an important role in the preventive strategy for oral cancer detection at an early stage. The aim of this study was to carry out a comparative quantitative analysis of the research material on the topic in one established database, Scopus and another emerging database, Dimensions.
    METHOD: An electronic search was performed in Scopus and Dimensions in April 2024 with the search subjects "Saliva," "Biomarkers," "Diagnosis," and "Oral Cancer." The retrieved data were analyzed using Biblioshiny for RStudio and MS Excel.
    RESULT: The search yielded 229 and 158 documents in Scopus and Dimensions, respectively. The data were studied to understand the coverage, concentration, and diversion of research articles. The analysis revealed high singularity index for Scopus and low overlap percentage between the two databases. Scopus was found to have higher citation count per article, however, the citation correlation between Scopus and Dimensions was found to be strong. Author productivity was found to be low in both the databases.
    CONCLUSION: Scopus and Dimensions vary in their scope, volume of data, and coverage policies. Both the databases have complimentary coverage on salivary biomarkers for oral cancer diagnosis. However, Scopus has a greater number of articles, sources, and citations resulting in better coverage of the topic.
    Keywords:  bibliometrics; biomarkers; early detection of cancer; mouth neoplasms; saliva
    DOI:  https://doi.org/10.1111/jop.13575
  57. World J Gastrointest Oncol. 2024 Aug 15. 16(8): 3687-3704
       BACKGROUND: Depression is strongly associated with colorectal cancer (CRC). Few bibliometric analyses have systematically summarized the research focus and recent progress in this field.
    AIM: To determine the research status and hotspots by bibliometric analysis of relevant publications on the relationship between CRC and depression.
    METHODS: Articles on depression in CRC patients were collected from the Web of Science Core Collection. CiteSpace and VOSviewer software were used to visualize bibliometric networks.
    RESULTS: From 2001 to 2022, Supportive Care in Cancer, the United States, Tilburg University, and Mols were the most productive and influential journal, country, institution, and author name. Co-occurrence cluster analysis of keywords placed quality of life, anxiety, and psychological stress in the center of the visual network diagram. Further clustering was performed for the clusters with studies of the relevant mechanism of action, which showed that: (1) Cytokines have a role essential for the occurrence and development of depressive disorders in CRC; (2) MicroRNAs have a role essential for the development of depressive disorders in CRC; (3) Some anticancer drugs have pro-depressant activity; and (4) Selective serotonin reuptake inhibitors have both antitumor and antidepressant activity.
    CONCLUSION: Life quality and psychological nursing of the cancer population were key topics. The roles of cytokines and microRNAs, the pro-depression activity of anticancer drugs and their antitumor properties deserve in-depth study.
    Keywords:  Bibliometric analysis; Colorectal cancer; Cytokines; Depression; Drugs; Mechanism
    DOI:  https://doi.org/10.4251/wjgo.v16.i8.3687
  58. Int Wound J. 2024 Aug;21(8): e14913
      The disturbance of the inflammatory microenvironment is a frequent pathological trait of diabetic wounds, contributing to the emergence of numerous chronic illnesses. This is crucial in both the development and recovery of wounds caused by diabetes. This study aims to perform a bibliometric analysis of research on the inflammatory microenvironment within the domain of diabetic wounds (DW) over the past 10 years. The objective is to map out the current global research landscape, pinpoint the most significant areas of study and offer guidance for future research avenues. Our research involved querying the Web of Science Core Collection (WoSCC) database for all pertinent studies on the inflammatory microenvironment in diabetic wounds (DW). We utilized bibliometric tools such as CiteSpace, VOSviewer and R (version 4.3.1) to identify and highlight the most impactful studies in the field. The study encompassed a review of 1454 articles published from 2014 to 2023, highlighting China and the United States as pivotal nations in the research of the inflammatory microenvironment in diabetic wounds (DW). Within this sphere, the University of Michigan and Harvard University in the United States, along with Shanghai Jiaotong University in China, emerged as the most prolific institutions. WANG Y from China was identified as the most productive author, while KUNKEL SL from the United States received the most citations. The research primarily focuses on topics such as wound healing, repair processes, angiogenesis, oxidative stress and macrophage activity. Additionally, "macrophage" and "delivery" were pinpointed as the leading subjects with promising research potential in this area. Research on the inflammatory microenvironment of diabetic wounds is rapidly advancing through active international collaboration. The study of new mechanisms related to the inflammatory microenvironment and the development of novel materials for repair based on this microenvironment represent emerging fields of future research, particularly in terms of translational applications. This may offer guidance and novel perspectives for further research in the area of the diabetic wound inflammatory microenvironment.
    Keywords:  bibliometric analysis; diabetic wound; immunity; inflammatory microenvironment; visualization
    DOI:  https://doi.org/10.1111/iwj.14913
  59. Front Neurol. 2024 ;15 1442145
       Background: Exploration of the benefits and timing of surgical decompression in spinal cord injury (SCI) has been a research hotspot. However, despite the higher volume and increasing emphasis on quality there remains no bibliometric view on SCI and surgical decompression. In this study, we aimed to perform bibliometric analysis to reveal the core countries, affiliations, journals, authors, and developmental trends in SCI and surgical decompression across the past 50 years.
    Methods: Articles and reviews were retrieved from web of science core collection between 1975 and 2024. The bibliometrix package in R was used for data analysis and visualizing.
    Results: A total of 8,688 documents were investigated, indicating an ascending trend in annual publications. The USA and China played as the leaders in scientific productivity. The University of Toronto led in institutional productions. Core authors, such as Michael G. Fehlings, showed high productivity, and occasional authors showed widespread interests. Core journals like Spine and Spinal Cord served as beacons in this field. The interaction of core authors and international collaboration accentuated the cross-disciplinary feature of the field. Prominent documents emphasized the clinical significance of early decompression in 24 h post SCI.
    Conclusion: Based on comprehensive bibliometric analysis and literature review, we identified the hotspots and future directions of this field: (1) further investigation into the molecular and cellular mechanisms to provide pre-clinical evidence for biological effects of early surgical decompression in SCI animal models; (2) further evaluation and validation of the optimal time window of surgical decompression based on large cohort, considering the inherent heterogeneity of subpopulations in complicated immune responses post SCI; (3) further exploration on the benefits of early decompression on the neurological, functional, and clinical outcomes in acute SCI; (4) evaluation of the optimal surgical methods and related outcomes; (5) applications of artificial intelligence-based technologies in spinal surgical decompression.
    Keywords:  bibliometric analysis; bibliometrix; functional recovery; spinal cord injury; surgical decompression
    DOI:  https://doi.org/10.3389/fneur.2024.1442145
  60. Nurs Res Pract. 2024 ;2024 6191008
      Succession planning is a commonly employed term in business strategy, referring to the systematic process of transferring leadership responsibilities to another employee to ensure the seamless continuity of an organization's operations. Today, this concept has acquired importance in various industries, including healthcare, with a specific focus on nursing. Several factors led nurse managers to consider preparing potential leaders for primary leadership roles due to the shortage of nurses, significantly impacting healthcare services and patient safety. Because of the importance of this topic, this present bibliometric analysis aims to analyze research studies conducted on succession planning and leadership development in nursing from 2000 to 2023 to identify research trends, key themes, and the evolution of research during this period. The Elsevier Scopus database was utilized for this analysis. This methodology identified (n = 326) journal studies based on the predefined keywords and timeframe. The data derived from this bibliometric analysis offers a robust foundation for conducting a systematic review, enabling a comprehensive synthesis and evaluation of the evidence in this significant field of study.
    DOI:  https://doi.org/10.1155/2024/6191008
  61. Skin Res Technol. 2024 Aug;30(8): e70017
       BACKGROUND: Melanoma is an aggressive malignancy primarily impacting the skin, mucous membranes, and pigment epithelium. The tumor microbial microenvironment encompasses both the microorganisms inhabiting the tumor vicinity and the environmental factors influencing their interactions. Emerging evidence highlights the pivotal role of the microbial immune microenvironment in melanoma.
    METHODS: We conducted an extensive review of scholarly works published from 2012 to 2022, utilizing The Web of Science Core Collection. Subsequently, we employed analytical tools such as VOSviewer, CiteSpace, and the R programming language to scrutinize prevailing research patterns within this domain.
    RESULTS: A sum of 513 articles were pinpointed, with notable input coming from the United States and China. Harvard University stood out as the top-contributing institution, while the journal Science received the most citations. Current research within this sphere chiefly focuses on two principal domains: the gut microbiota and the PD-L1 pathway concerning melanoma treatment.
    CONCLUSION: The study offers an extensive analysis and overview of the worldwide research landscape concerning the immune microenvironment with a focus on microbes in melanoma. It underscores the promising prospects for harnessing the microbial immune microenvironment's potential in melanoma. These findings furnish valuable insights and guidance for advancing scientific inquiry and refining clinical approaches within this dynamic field.
    Keywords:  immune microenvironment; melanoma; microbes; microbial microenvironment; tumor immunotherapy
    DOI:  https://doi.org/10.1111/srt.70017
  62. Oral Dis. 2024 Aug 20.
       OBJECTIVES: To analyze gender inequities and trends in the authorship of articles published in high-impact factor journals of the field of Oral Medicine and Pathology.
    METHODS: The gender and country of first and last authors were retrieved from original articles published between 2000 and 2022. Poisson regression models and classification and regression tree (CART) analysis were performed.
    RESULTS: A total of 6595 studies were analyzed for first authorship, and 6627 for last authorship. Only 39.2% (CI 95% 38.0-40.3) of the first authors and 24.1% (CI 95% 23.1-25.1) of the last authors were females. Females consistently faced underrepresentation throughout the 23-year evaluation. The only region where female first authors are not a minority is Latin America. Having a female as the last author increased the prevalence of females in the first author position by 42% (PR = 1.42, CI 95% [1.30-1.54]). The most important discriminant variable by CART was the first author region.
    CONCLUSION: Although a slight decrease in underrepresentation was noted over the period, after 2020, the gender gap tended to widen for both first and last authors. It is crucial to implement measures aimed at attracting, retaining, and advancing women in the field of science, while also actively monitoring advancements toward achieving gender equity.
    Keywords:  authorship; gender equity; oral medicine; oral pathology; woman dentist
    DOI:  https://doi.org/10.1111/odi.15105
  63. Front Med (Lausanne). 2024 ;11 1356825
      Idiopathic pulmonary fibrosis (IPF) garners considerable attention due to its high fatality rate and profound impact on quality of life. Our study conducts a comprehensive literature review on IPF using bibliometric analysis to explore existing hot research topics, and identifies novel diagnostic and therapeutic targets for IPF using bioinformatics analysis. Publications related to IPF from 2013 to 2023 were searched on the Web of Science Core Collection (WoSCC) database. Data analysis and visualization were conducted using CiteSpace and VOSviewer software primarily. The gene expression profiles GSE24206 and GSE53845 were employed as the training dataset. The GSE110147 dataset was employed as the validation dataset. We identified differentially expressed genes (DEGs) and differentially expressed genes related to oxidative stress (DEOSGs) between IPF and normal samples. Then, we conducted Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. The hub genes were screened by protein-protein interaction (PPI) networks and machine learning algorithms. The CIBERSORT was used to analyze the immune infiltration of 22 kinds of immune cells. Finally, we conducted the expression and validation of hub genes. The diagnostic efficacy of hub genes was evaluated by employing Receiver Operating Characteristic (ROC) curves and the associations between hub genes and immune cells were analyzed. A total of 6,500 articles were identified, and the annual number of articles exhibited an upward trend. The United States emerged as the leading contributor in terms of publication count, institutional affiliations, highly cited articles, and prolific authorship. According to co-occurrence analysis, oxidative stress and inflammation are hot topics in IPF research. A total of 1,140 DEGs were identified, and 72 genes were classified as DEOSGs. By employing PPI network analysis and machine learning algorithms, PON2 and TLR4 were identified as hub genes. A total of 10 immune cells exhibited significant differences between IPF and normal samples. PON2 and TLR4, as oxidative stress-related genes, not only exhibit high diagnostic efficacy but also show close associations with immune cells. In summary, our study highlights oxidative stress and inflammation are hot topics in IPF research. Oxidative stress and immune cells play a vital role in the pathogenesis of IPF. Our findings suggest the potential of PON2 and TLR4 as novel diagnostic and therapeutic targets for IPF.
    Keywords:  bibliometrics; bioinformatics; idiopathic pulmonary fibrosis; immune infiltration; oxidative stress
    DOI:  https://doi.org/10.3389/fmed.2024.1356825
  64. Heliyon. 2024 Aug 15. 10(15): e35469
       Objective: To explore the research progress and trends on mineral elements and depression.
    Methods: After querying the MeSH database and referring to the search rules, the search terms were selected and optimized to obtain the target literature collection. We analyzed the general characteristics of the literature, conducted network clustering and co-occurrence analysis, and carried out a narrative review of crucial literature.
    Results: Bipolar disorder was a dominant topic in the retrieved literature, which saw a significant increase in 2010 and 2019-2020. Most studies focused on mineral elements, including lithium, calcium, magnesium, zinc, and copper. The majority of journals and disciplines were in the fields of psychiatry, neuropsychology, neuropharmacology, nutrition, medical informatics, chemistry, and public health. The United States had the highest proportion in terms of paper sources, most-cited articles, high-frequency citations, frontier citations, and high centrality citation. Regarding the influence of academic institutions, the top five were King's College London, the Chinese Academy of Sciences, University of Barcelona, INSERM, and Heidelberg University. Frontier keywords included bipolar disorder, drinking water, (neuro)inflammation, gut microbiota, and systematic analysis. Research on lithium response, magnesium supplementation, and treatment-resistant unipolar depression increased significantly after 2013.
    Conclusion: Global adverse events may have indirectly driven the progress in related research. Although the literature from the United States represents an absolute majority, its influence on academic institutions is relatively weaker. Multiple pieces of evidence support the efficacy of lithium in treating bipolar disorder (BD). A series of key discoveries have led to a paradigm shift in research, leading to increasingly detailed studies on the role of magnesium, calcium, zinc, and copper in the treatment of depression. Most studies on mineral elements remain diverse and inconclusive. The potential toxicity and side effects of some elements warrant careful attention.
    Keywords:  Bibliometric analyses; CiteSpace; Depression; Mineral elements; Status quo
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35469
  65. J Shoulder Elbow Surg. 2024 Aug 19. pii: S1058-2746(24)00582-2. [Epub ahead of print]
       BACKGROUND: As orthopedic surgery becomes increasingly competitive, orthopedic surgeons are now pursuing advanced degrees more frequently to enhance their resumes or gain additional expertise. The specific impact of this additional training and education on a surgeon's career trajectory is not well defined. The purpose of this study was to understand the impact of an advanced degree on the academic career of orthopedic shoulder and elbow surgeons.
    METHODS: Orthopedic shoulder and elbow fellowship-trained surgeons were identified using the directory listed on the American Shoulder and Elbow Surgeons website. Demographics, education, and current professional roles were obtained. Research productivity was obtained using SCOPUS and Google Scholar. Advanced degrees were defined as those additional to the primary medical degree (Doctor of Medicine [MD] or Doctor of Osteopathic Medicine [DO]). Outcome measures collected included timing of advanced degree obtainment, current academic and leadership roles, leadership on journal editorial boards, and research productivity. Statistical analysis was performed using the chi-square test and Mann-Whitney U test to determine the association of advanced degrees on outcome measures.
    RESULTS: In total, 893 orthopedic shoulder and elbow surgeons were identified, of whom 129 had advanced degrees. Most common advanced degrees included Master of Science (MS/MSc; 43%), Master of Business Administration (MBA; 23%), and Doctor of Philosophy (PhD; 13%). The most common period of degree obtainment was before medical school (35%) with the least common times being after medical school/before residency (0.9%) and between residency and fellowship training (0.9%). Surgeons who held advanced degrees demonstrated greater research productivity, with a higher h-index (p < 0.001), a greater number of citations (p < 0.001), and more publications (p < 0.001). Of the 523 shoulder and elbow surgeons who worked at an academic institution, those holding advanced degrees were more likely to serve as orthopedic department chair (p < 0.001) and serve an editorial board position (< 0.001).
    CONCLUSION: This study found that having an advanced degree as an orthopedic shoulder and elbow surgeon was linked to higher research impact and productivity and an increased likelihood of becoming a department chair and holding an editorial position. These significant findings can help future trainees and department leadership in understanding the importance and impact of additional training on career trajectories for academic faculty.
    Keywords:  Shoulder; advanced degree; dual degree; elbow; orthopedic career advancement; research productivity
    DOI:  https://doi.org/10.1016/j.jse.2024.07.010
  66. Cureus. 2024 Jul;16(7): e65135
      Geriatric trauma is a critical area of research owing to the increasing elderly population and the unique challenges associated with their injuries. This study aimed to explore the intellectual structure, growth, spatial analysis, seminal publications, most frequent keywords, trending topics, conceptual structure, and thematic evolution of geriatric trauma research (GTR). A comprehensive analysis was conducted using VOSviewer (Centre for Science and Technology Studies, Leiden University, The Netherlands) and Biblioshiny (K-Synth Srl, University of Naples Federico II, Italy) to examine a corpus of scholarly publications (N = 682) related to GTR (2004-2024). Bibliographic data were collected from the Scopus database and analyzed to highlight the key findings and trends. The analysis revealed the leading contributors to GTR. Over the years, there has been an increased interest in geriatric trauma, as demonstrated by the increasing trend in research publications. Collaboration patterns among nations were determined through spatial analysis, and insights into significant topics and their influence were offered by influential publications. Keywords used frequently as well as current issues formed part of this study's findings, which give insight into what was most focused on within the GTR. Themes and their development over time were made explicit by revealing their conceptual structures and thematic evolutions. GTR has increased significantly. Interdisciplinary approaches are suggested for future research. Furthermore, gaps need to be addressed using technological advancements that will help improve geriatric trauma management and lead to better patient outcomes.
    Keywords:  bibliometrics; conceptual mapping; geriatric trauma; hotspots; trending topics
    DOI:  https://doi.org/10.7759/cureus.65135
  67. Front Pharmacol. 2024 ;15 1438227
      Introduction: Silver nanoparticles (AgNPs) have gained significant attention in biomedical applications due to their unique physicochemical properties. This review focuses on the roles of AgNPs in antimicrobial activity, anticancer therapy, and wound healing, highlighting their potential to address critical health challenges. Methods: A bibliometric analysis was conducted using publications from the Scopus database, covering research from 2002 to 2024. The study included keyword frequency, citation patterns, and authorship networks. Data was curated with Zotero and analyzed using Bibliometrix R and VOSviewer for network visualizations. Results: The study revealed an increasing trend in research on AgNPs, particularly in antimicrobial applications, leading to 8,668 publications. Anticancer and wound healing applications followed, with significant contributions from India and China. The analysis showed a growing focus on "green synthesis" methods, highlighting a shift towards sustainable production. Key findings indicated the effectiveness of AgNPs in combating multidrug-resistant bacteria, inducing apoptosis in cancer cells, and promoting tissue regeneration in wound healing. Discussion: The widespread research and applications of AgNPs underscore their versatility in medical interventions. The study emphasizes the need for sustainable synthesis methods and highlights the potential risks, such as long-term toxicity and environmental impacts. Future research should focus on optimizing AgNP formulations for clinical use and further understanding their mechanisms of action. Conclusion: AgNPs play a pivotal role in modern medicine, particularly in addressing antimicrobial resistance, cancer treatment, and wound management. Ongoing research and international collaboration are crucial for advancing the safe and effective use of AgNPs in healthcare.
    Keywords:  antimicrobial resistance; cancer nano therapy; silver nanoparticles; sustainable synthesis methods and bibliometric trend analysis; wound healing innovations
    DOI:  https://doi.org/10.3389/fphar.2024.1438227
  68. Chemosphere. 2024 Aug 16. pii: S0045-6535(24)02016-2. [Epub ahead of print]364 143119
      The pollution resulting from the emergence of the contaminant perchlorate is anticipated to have a substantial effect on the water environment in the foreseeable future. Considerable research efforts have been devoted to investigating treatment technologies for addressing perchlorate contamination, garnering widespread international interest in recent decades. A systematic review was conducted utilizing the Web of Science, Scopus, and Science Direct databases to identify pertinent articles published from 2000 to 2024. A total of 551 articles were chosen for in-depth examination utilizing VOS viewer. Bibliometric analysis indicated that countries such as China, the United States, Chile, India, Japan, and Korea have been prominent contributors to the research on this topic. The order of ClO4- occurrence was as follows: surface water > groundwater > drinking water. Various remediation methods for perchlorate contamination, such as adsorption, ion-exchange, membrane filtration, chemical reduction, and biological reduction, have been suggested. Furthermore, the research critically evaluated the strengths and weaknesses of each approach and offered recommendations for addressing their limitations. Advanced technologies have shown the potential to achieve notably enhanced removal of perchlorate and co-contaminants from water sources. However, the low concentration of perchlorate in natural water sources and the high energy consumption related to these technologies need to be solved in order to effectively remove perchlorate from water.
    Keywords:  Bibliometric analysis; Occurrence; Perchlorate; Treatment; Water environment
    DOI:  https://doi.org/10.1016/j.chemosphere.2024.143119
  69. Front Sports Act Living. 2024 ;6 1410923
      Maintenance and improvement of an individual's overall well-being require a multidisciplinary approach that encompasses everything from oral health care to regular physical exercise. The notion that poor oral health can influence general health and athletic performance has sparked an interest in this relationship. This study offers an overview of relevant research and a knowledge map,and discusses publication metrics and key topics concerning the relationship between physical activity or exercise and oral diseases. We searched the Web of Science database for articles published in the 21st century that addressed the relationship between physical activity and oral diseases. Under the stipulated inclusion criteria, a rigorous selection process yielded 276 from 3,883 retrieved articles. The articles were classified by what was assessed as follows: occurrence of oral diseases in athletes or sports enthusiasts (n = 174); impact of physical activity or exercise on the oral cavity (n = 59); effects of oral changes on sports performance and physical fitness (n = 31); and the connection between oral health status, physical activity or exercise, and systemic conditions (n = 12). Orofacial trauma has received the most attention among all investigated oral diseases. However, there is a need for greater attention of dysfunctional habits that can contribute to premature tooth wear, as well as oral inflammatory diseases that can have systemic implications. This mapping can encourage the development of new primary research.
    Keywords:  athletic performance; exercise; oral health; sports medicine; stomatognathic system
    DOI:  https://doi.org/10.3389/fspor.2024.1410923
  70. Heliyon. 2024 Aug 15. 10(15): e35299
      Lipophagy is defined as the autophagic degradation of lipid droplets. It is a selective autophagy process that can continuously circulate and redistribute metabolites to maintain the body's energy balance. Over the last ten years, there has been a significant increase in the amount of literature on lipophagy, making it more challenging to track the field's advancement using conventional techniques. The data from the lipophagy literature published in the last ten years was converted into visual representations with the use of bibliometric tools. An increasing number of countries and institutions are delving further into lipophagy research with the support of visualization technologies. The five main illnesses of cancer, atherosclerosis, fatty liver, hyperlipidemia, and neurodegenerative diseases have become study opportunities, as have the mechanisms of macroautophagy, microautophagy, and chaperone-mediated autophagy.
    Keywords:  Atherosclerosis5; Bibliometric2; Cancer6; Fatty liver4; Lipid metabolism3; Lipophagy1
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35299
  71. Eur J Orthod. 2024 Oct 01. pii: cjae042. [Epub ahead of print]46(5):
       BACKGROUND: The published literature represents the fundamental basis of any academic specialty, including orthodontics. Orthodontic research outputs provide useful insight into clinical and research priorities, which can help inform future research efforts and resource outputs. In recent years, the need for more patient-reported outcomes in orthodontic research has been highlighted.
    OBJECTIVES: To identify the most common reported research subjects in orthodontics between 2013-23; (2) identify the main outcomes and types of study design associated with this research, including study design related to patient-reported outcomes; and (3) identify trends in this research activity based upon these findings.
    MATERIAL AND METHODS: A literature search was performed in a single electronic database (Scopus) to return all indexed publications with relevance to orthodontics published from 2013 to 2023. The 50 most-cited publications per year were then identified. Publication characteristics were extracted using a data collection sheet. Descriptive statistics including frequency distributions were calculated.
    RESULTS: A total of 14 397 publications were identified. Publications on orthodontic bonding made up 7.02% of all output, followed by materials (5.88%) and tooth movement (5.42%). Subsequent analysis of the most-cited publications per year revealed the most frequently published subjects were aligners (12.5%), orthodontic tooth movement (9.45%), and digital workflow (9.09%), and the most common study designs were in vitro (19.09%) and retrospective observational studies (15.45%). The most common outcome type was morphological features of malocclusion (26.9%). Conversely, patient-focused measures were only reported in 12.7% of studies.
    CONCLUSIONS: Orthodontic research outputs are dynamic but do show consistent research interest in certain subjects. There is a predilection for the reporting of clinician-focused outcomes; whilst these have some value, more efforts should be focused on conducting rigorous and robust studies that include patient-reported outcomes.
    Keywords:  metrics; orthodontics; research outcomes
    DOI:  https://doi.org/10.1093/ejo/cjae042
  72. Heliyon. 2024 Aug 15. 10(15): e35227
      Based on the China National Knowledge Infrastructure (CNKI) and Web of Science (WOS) databases, this article analyzes the deductive context, cooperation network, and research hotspots of land development rights (LDR) research in the Chinese and international literature by using CiteSpace software, and it also explores the implications of this research for the theory and practice of national territory spatial planning (NTSP) in China. The results show that (1) the literature on LDR in Chinese and international journal articles initially appeared in 1995 and 1973, respectively, researches in China experienced three stages: embryonic fluctuating development, rapid growth and stable development, and wave development, while international researches experienced two stages: embryonic fluctuating and a gradually increasing development. (2) Among these scholars and research institutions, there is no obvious difference between Chinese and international scholars, while the Renmin University of China and the State University System of Florida are the research institutions with the largest number of Chinese and international journal articles, respectively. (3) In terms of publishing journals, international journals mainly focus on land policy, cities, and resource fields, while Chinese journals mainly focus on the agricultural economy, civil and commercial law, economic systems, and macroeconomic management fields. (4) The direction and scale of thematic research vary greatly, with Chinese research mainly conducted from the perspectives of rights attribution and benefits distribution, while international research mainly focuses on the operation of the right-to-development system and its impact on the environment. In the future, studies focus on China's need to strengthen the research and institutional practice of LDR at the legal level, value level, and extension level following national conditions, formulate a land value-added benefit distribution system with efficiency and fairness, and strengthen the practice of LDR in China's NTSP based on the differences between urban and rural development.
    Keywords:  China's national territory spatial planning; CiteSpace; Hotspot research; Land development rights; Land value-added benefits; Visual analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35227
  73. An Acad Bras Cienc. 2024 ;pii: S0001-37652024000501317. [Epub ahead of print]96(3): e20231171
      A scientometric analysis of the Neotropical Otter is essential to establish the progress in studies with the species, in order to improve its conservation status. This study aimed to identify, categorize, and evaluate published scientific papers on Lontra longicaudis. Quantitative data was analyzed through absolute and relative frequencies, represented by tables and maps. The results showed that the publications on the Neotropical Otter increased since 1993 and have been primarily published in a specific journal (IUCN Otter Spec. Group Bull.) on the subfamily Lutrinae. Most authors reside in countries such as Brazil, Mexico, and Colombia, and publish predominantly in English. The majority of studies were conducted with free-living specimens, notably in the Brazilian state of Rio Grande do Sul and in Mexico. The most commonly used keywords match the most frequent subjects: "place of occurrence" and "diet". Despite the increase in publications, research on the Neotropical Otter is still largely limited to Brazil, Mexico, and sites near research institutions. Gaps on essential information for the species conservation, such as its biology, ecology, and behavior, were identified. The need for further studies on the Neotropical Otter in all the territory it inhabits is evident.
    DOI:  https://doi.org/10.1590/0001-3765202420231171
  74. J Multidiscip Healthc. 2024 ;17 4023-4041
       Introduction: Stroke is one of the leading causes of death and disability globally, and low-income countries such as Malawi bear a heavy burden. Tailored, high-quality research is essential for bridging existing gaps and improving the healthcare provided in low-resource settings while maximizing available resources.
    Aim: This mapping study aimed to synthesize the current state of stroke research in Malawi.
    Methods: Six databases were thoroughly searched: CINAHL complete, Ovid MEDLINE and EMBASE, Web of Science Core Collection, PubMed, and Google Scholar.
    Results: The search retrieved 598 references and identified 20 studies published between 2005 and 2023. Of these, 70% were conducted at Queen Elizabeth Central Hospital only; open-access journals published 95% of the studies. Cross-sectional studies were the most common (50%), followed by case-control studies (20%). The Malawi-Liverpool-Wellcome Trust Clinical Research Program authors contributed the most articles as main authors (25%). The number of citations per article ranged from 0 to 168 on Google Scholar, and the number of authors per article ranged from 1 to 15. Authors from thirty-five different institutions from 11 other countries partnered with Malawi on stroke articles, and England contributed 45.7% of the institutions. Most articles focused on pathophysiology (30%), followed by diagnosis (20%) and stroke management (15%). The highest number of participants included in the analysis was 739 and the highest number of stroke participants was 222. The identified challenges included the need for more infrastructure and under-utilization of available services. The Wellcome Trust has emerged as the primary funding agency for stroke research in Malawi.
    Conclusion: The study found limited collaboration among local institutions in Malawi, with most research focused in Blantyre District. There is a critical need for increased interdisciplinary teamwork to boost nationwide research.
    Keywords:  corroboration; distribution; methods; output
    DOI:  https://doi.org/10.2147/JMDH.S476012
  75. J Am Vet Med Assoc. 2024 Sep 01. 262(9): 1146
      
    DOI:  https://doi.org/10.2460/javma.262.9.1146
  76. Heliyon. 2024 Aug 15. 10(15): e35324
      Microalgae are being recognized as the key contributor to sustainability in many sectors, starting from energy up to food industries. The microorganism has also been utilized as environmental remediator, capable of converting organic compounds into economically valuable biomass. To optimize the use of microalgae in these sectors, researchers have explored various approaches, of which is the use of bacteria. The interaction between bacteria and microalgae can potentially be harnessed, but its complexity requires extensive research. Herein, we present the bibliometric analysis on microalgal-bacterial interactions. The metadata of published literature was collected through Scopus database on August 4, 2023. The downloaded.csv file was uploaded to VOSViewer and biblioshiny for network visualization. We found that the research has gained a lot of attention from researchers since 2012 with an exponential increase of the publication number. The United States and China are leading the research with a strong collaboration. Based on the research sub-topic clusters, the interaction is mostly studied for wastewater treatment, biomass production, and algal bloom control. Updated reviews on this topic reveal that researchers are now focus on optimizing the efficacy of microalgae-bacteria system, investigating the modes of actions, and identifying challenges in its real-world implementation. The microalgal-bacterial interaction is a promising approach for microalgae utilization in wastewater treatment, biomass production, and algal bloom control.
    Keywords:  Algacidal; Bacteria; Bibliometric; Flocculation; Microalgae
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35324
  77. Farm Comunitarios. 2024 Jan 15. 16(1): 3-4
      The reason for existence of a scientific journal is to disseminate knowledge of science. The objective is a continuous improvement in the quality of what is published and an increase in the number of readers. In this sense, the impact factor is an indicator that helps us visualize the improvement in the quality of our journal. To improve this impact factor, indexing in the most used databases is very important.Farmacéuticos Comunitarios is indexed in several index journals but we were missing the most used ones. In this last year we have requested indexing in the most important ones, SCOPUS and Medline. In November we received SCOPUS approval and are close to getting it on Medline. In September we were approved by the editorial criteria and in December by the scientists. We only need the technical criteria to be able to appear in Medline and in its online version PubMed. We are working on it and it is very likely that within a year we will be indexed in PubMed.
    Keywords:  Community Pharmacy; Indexing,; Medline; PubMed; SCOPUS; Scientific journals
    DOI:  https://doi.org/10.33620/FC.2173-9218.(2024).01
  78. Cureus. 2024 Jul;16(7): e64787
      Background The publication of scholarly work in peer-reviewed journals is a well-established method for disseminating knowledge and findings to a global audience. However, the publishing process is constantly evolving and encountering various obstacles that hinder progress. Despite a significant increase in the number of research projects undertaken, there are few studies evaluating the challenges faced by investigators in publishing their research. This study aims to identify the factors and elements that influence the publication process after the completion of research. Methods This study included 759 projects approved by the Institutional Ethics Committee (IEC) from 2016 to 2021 at a tertiary care centre in South India. A list of these approved projects was analysed for overall output in terms of publication and completion. Investigators were contacted and interviewed using a validated, 15-question survey to identify various factors influencing scientific publications. Results A total of 759 projects approved by the IEC from 2016 to 2021 were analyzed. It was found that only 36.72% of studies were completed by faculty members, and the publication conversion rate was 34.24%. A single-point analysis showed a statistically significant lower conversion rate for resident articles (p = 0.032). The 15-point analysis detailed the factors influencing publication conversion, revealing that the majority of researchers publish based on academic and research interests (68.89% and 72.12%, respectively). Various deterrents to publication, such as study design, statistical analysis, journal selection, and knowledge about journal submission, were identified. Notably, 98.4% of researchers expressed a desire to publish more in the future, highlighting the importance of this study. Conclusion The study highlights areas that require attention to facilitate and augment research. It identifies the real gaps in the publication process and suggests points of intervention needed to enhance the research environment, increase publication rates, and establish demand-based research support units in the medical education sector.
    Keywords:  academics; journals; medical education; publications; research
    DOI:  https://doi.org/10.7759/cureus.64787
  79. An Acad Bras Cienc. 2024 ;pii: S0001-37652024000501804. [Epub ahead of print]96(3): e20230942
      In this paper, we looked at the collaboration publishing patterns for groups of Global South countries (Latin America, Africa, ASEAN, Asian, BRICS), as well as publishing parameters. We looked at financing and the relationships between these groups and the Global North. Data from 2002 to 2021 was collected from InCites ® (Web of Science, Clarivate Analytics) and SciVal® (Scopus Elsevier). The impact was lower for BRICS, while Latin America and Asean countries tended to have a higher Field Weighted Citation Impact. Good Health and well-being (SDG 3) dominates South-South Collaborations. Asian countries showed a higher percentage of Affordable and Clean Energy (SDG7), while Africa and Latin America had a higher rate of Zero Hunger (SDG1). Each region shows different production profiles, but collaboration with the Global North is necessary for all regions. Intra-regional shows a lower impact than inter-regional financing, calling attention to the increasing influence of China in all regions, except for Latin America. The data analysed can be used for orienting South-South scientific Collaboration programs, focusing on pre-existent synergies and on where policy changes and results can be maximised.
    DOI:  https://doi.org/10.1590/0001-3765202420230942
  80. J Shoulder Elbow Surg. 2024 Aug 14. pii: S1058-2746(24)00575-5. [Epub ahead of print]
       INTRODUCTION: Division Chiefs (DCs) and department leadership play an integral role within the service, and in the department as a whole. The goal of this study was to assess the demographics and academic characteristics of the leadership in orthopedic shoulder and elbow services across academic centers in the United States and comment on the diversity within these leadership positions.
    METHODS: Academic medical centers were identified using the FRIEDA database. DCs were identified using the hospitals' respective websites where data such as sex, race/ethnicity, academic rank, fellowship institution, and time since graduating fellowship. Scopus database was used to determine individual h-indices.
    RESULTS: Of 198 academic programs identified, 49 were found to have a DC of the orthopedic shoulder and elbow division. An additional 26 programs were noted to have a shoulder and elbow division, but were not found to have a DC of the division. These DCs were mostly White (n=43, 87.8%), with only 6 identified DCs with a different ethnicity. Forty-five of the DCs (91.8%) were male and 4 were female (8.2%). The average time out of fellowship was 20.7 years and the average h-index was 18.9. More than 20% of the DCs trained at Columbia's Neer shoulder and elbow Fellowship. Six DCs were current or past president of ASES and 5 DCs completed the ASES traveling fellowship.
    CONCLUSIONS: There is a paucity of available research on demographic and leadership characteristics in academic orthopedic shoulder and elbow. Shoulder and elbow DC had average h-index of 18.9 and 20% trained at one fellowship. There also opportunities for increased gender/racial/ethnic diversity among the leadership of shoulder and elbow divisions.
    Keywords:  Diversity; Division Chief; Leadership; Shoulder and Elbow
    DOI:  https://doi.org/10.1016/j.jse.2024.07.004
  81. J Plast Reconstr Aesthet Surg. 2024 Jul 31. pii: S1748-6815(24)00420-0. [Epub ahead of print]97 124-132
       BACKGROUND: The patient-reported outcomes measurement information system (PROMIS) was developed by investigators funded by the National Institutes of Health as a standardized means of directly assessing the patients' perspectives across domains. PROMIS domains include physical function, pain, fatigue, emotional distress, and social health. Various studies have reported increased utilization of PROMIS in research articles in specific specialties; however, the extent to which PROMIS has been employed in the field of plastic and reconstructive surgery remains unclear. The goal of the present study was to characterize the prevalence and trends of PROMIS within plastic and reconstructive surgery articles.
    METHODS: Literature search was conducted across multiple databases for PROMIS studies within plastic surgery literature. We identified 136 articles and the following data were extracted: author name, journal, impact factor, country of origin, year of publication, publication type, subspecialty, study size, and PROMIS measures used.
    RESULTS: In this study, 136 studies met the inclusion criteria. There was an overall increasing trend in the number of PROMIS studies published. The most common subspecialties that used PROMIS measures were general reconstruction (n = 24), hand (n = 9), and burn (n = 5). The most used PROMIS measures were the pain interference (n = 26), pain intensity (n = 15), and depression (n = 13). A total of 24 journals included PROMIS studies with a mean impact factor of 3.73 (SD = 3.2). The most common country of origin was the United States (n = 42).
    CONCLUSION: The data demonstrated an increasing use of PROMIS within plastic surgery across a wide variety of subspecialities and study designs. The characterization of these trends allows researchers and clinicians alike to gain a greater understanding of this powerful tool in measuring patient care.
    Keywords:  Outcome measures; PROMIS; Patient-reported outcomes; Plastic surgery; Reconstructive surgery
    DOI:  https://doi.org/10.1016/j.bjps.2024.07.049
  82. Tob Use Insights. 2024 ;17 1179173X241271566
       Introduction: Tobacco companies conduct and fund research. They are not always interested in open-ended research. They promote their interests through public relations campaigns. It's a proven fact that they influence the scientific community by impairing scientific reputation, especially in the case of health-related research.
    Methods: To obtain a comprehensive picture of research and funding activities of the tobacco industry as well as studies about the tobacco industry, respective scientific articles were analyzed in terms of temporal aspects, research areas, networking, and funding sources using established and advanced bibliometric methods.
    Results: We found the foci of publications with tobacco industry involvement or funding were mainly in chemistry, toxicology, pharmacology, and agricultural sciences. Health-related scopes occurred much less frequently. In contrast, health and medical sciences were the main focus of publications on the tobacco industry. The Chinese state-owned CNTC was the most research-involved tobacco company and often networked with Chinese academic institutions. Whereas, Western universities, on the other hand, collaborated with tobacco companies to a much lesser extent.
    Conclusion: Conflicts of interest of researchers or academic institutions with the tobacco industry occur repeatedly. That is highly problematic and should not be ignored by the scientific community. The science and the public should be skeptical about tobacco industry-supported research.
    Keywords:  big tobacco; conflicts of interest; funding; interest-led research support; research output; tobacco companies
    DOI:  https://doi.org/10.1177/1179173X241271566
  83. Heliyon. 2024 Aug 15. 10(15): e35460
      The retraction of publications is a crucial aspect of scientific integrity; it aims to correct the literature and alert scholars and the general public by identifying and labelling articles that contain erroneous data, unreliable findings, or flawed conclusions. Identifying and characterizing retracted articles within the scientific literature is thus very important. The aims of this article were to characterize retracted articles in the ophthalmological literature. One hundred and fifty-one retracted articles published between 1966 and 2023 were retrieved. The number of retracted articles showed an upward trend from 2020 onwards. Ocular oncology (n = 37, 24.5 %) was the most frequently represented subspeciality in the retracted articles, despite retina and uveitis being the most published. The most frequent reason for retraction was fake data (n = 62, 38 %). The labelling of retracted articles on some websites was unsatisfactory, especially on the free-access illegal platform Sci-Hub. On the other hand, platforms such as Dimensions, Scite and Retraction Watch exhibit promising accuracy. Improving the labelling of retractions is needed to reduce the citation of articles after they have been retracted. Solutions to reach this goal are discussed in this article.
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e35460
  84. Front Physiol. 2024 ;15 1427038
      Physical inactivity can lead to frailty and negative health outcomes in middle-aged to older adults. Sedentary individuals have double the risk of death compared to those who engage in high levels of physical activity (PA). The advantages of practicing PA in older age are significant, with regular, moderate-intensity activity (150 min per week)being consistently linked with a decreased risk of chronic disease, cognitive decline, and mortality. Therefore, the study aimed to carry out a bibliometric review related to the terms "Physical activity," "Functional capacity" and "Aging" including all the documents published in the Web of Science Core Collection until 31st December 2023. The sample was made up of 231 studies related to the topic. The results reported that the first document was published in 1994. However, there was no continuity in the publication of the documents till 1998, which was the first year with at least one document published. Considering 1998 as the first year, it is observed an exponential growth of 77.4%, between the oldest (1997-2008) and contemporaneous studies (2008-2023), in which "Geriatric Gerontology" was the Web of Science category with the highest number of documents (n = 59). The journal "Experimental Gerontology" was associated with the largest number of published documents (n = 7), being indexed in Quartil 2. The years 2009 had the highest number of citations (n = 1811), with a total of 7 documents published and 2018 with the higher number of documents (n = 25). These results reported the importance of PA in elderly people, and how it influences the risk of falls, improving the balance and the functional capacity. Thus, it is important to carry out programmes to promote physical activity to this population and reduce the risk of falls and the presence of diseases.
    Keywords:  co-authorship; elderly; journals; sedentary lifestyle; trend
    DOI:  https://doi.org/10.3389/fphys.2024.1427038
  85. J Commun Healthc. 2024 Aug 21. 1-10
       BACKGROUND: Cyberbullying research has gained considerable attention among scholars due to the proliferation and diversification of the digital media platforms. Although cyberbullying research has a robust empirical nature, the research is more difficult to define and deserves close investigation. In response to the situation, we have examined topics, forms, context, media, predictive factors, outcomes, utilization of methodology, and research trends in cyberbullying research from 2014 to 2023.
    METHODS: This study analyzed 3,588 articles to investigate the trend and development of cyberbullying research using the Scopus academic databases.
    RESULTS: 85.87% of research focused on cyberbullying as 'social issues'. 71.57% of articles focused on cyberbullying itself rather than specific forms of cyberbullying. 50.81% of articles focused on cyberbullying in middle/high school contexts. Most research did not state any predictive factors (39.83%) or outcomes (60.17%) suggested. The predominant research method used in cyberbullying research was via surveys (30.69%), while the second phase of research dominated the cyberbullying research agenda (victims and bullies in cyberbullying).
    CONCLUSIONS: Although Cyberbullying research has increased, broadened, and diversified over time, it still focuses primarily on the first phase of the research agenda of cyberbullying issues. The findings of this study provides a framework for new insights for future cyberbullying research and practices by suggesting exploration to different mechanisms of cyberbullying such as: victims/bullies, effects, and improvement of cyberbullying beyond the issues of cyberbullying itself.
    Keywords:  Cyberbullying; conceptual framework; methodological approaches; research trends; topical analysis
    DOI:  https://doi.org/10.1080/17538068.2024.2393920
  86. Stud Health Technol Inform. 2024 Aug 22. 316 944-948
      In the ever-evolving landscape of medical research and healthcare, the abundance of scientific articles presents both a treasure trove of knowledge and a daunting challenge. Researchers, clinicians, and data scientists grapple with vast amounts of unstructured information, seeking to extract meaningful insights that can drive advancements in the biomedical domain including, research trends, patient care, drug discovery, and disease understanding. This paper utilizes the topic extraction algorithms on Breast Cancer Research to shed light on the current trends and the path to follow in this field. We utilized TextRank and Large Language Models (LLM) using the TripleA tool to extract topics in the field, analyzing and comparing the results.
    Keywords:  Bibliometric Analysis; Breast Cancer; Large Language Models; Natural Language Processing; Text Rank; Topic Extraction
    DOI:  https://doi.org/10.3233/SHTI240566
  87. Pragmat Obs Res. 2024 ;15 151-164
       Background: Routinely collected electronic healthcare records (EHRs) document many details of a person's health, including demographics, preventive services, symptoms, tests, disease diagnoses and prescriptions. Although not collected for research purposes, these data provide a wealth of information which can be incorporated into epidemiological investigations, and records can be analysed to understand a range of important health questions. We aimed to understand the use of routinely collected health data in epidemiological studies relating to three of the most common chronic respiratory conditions, namely: asthma, chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD). We also characterised studies using EHR data to investigate respiratory diseases more generally, relative to cardiovascular disease and COVID-19, to understand trends in the use of these data.
    Methods: We conducted a search of the Scopus database, to identify original research articles (irrespective of date) which used data from one of the following most frequently used UK EHR databases: Clinical Practice Research Datalink (including General Practice Research Database (CPRD's predecessor)), The Health Improvement Network and QResearch, defined through the presence of keywords. These databases were selected as they had been previously included in the works of Vezyridis and Timmons.
    Findings: A total of 716 manuscripts were included in the analysis of the three chronic respiratory conditions. The majority investigated either asthma or COPD, whilst only 28 manuscripts investigated ILD. The number of publications has increased for respiratory conditions over the past 10 years (888% increase from 2000 to 2022) but not as much as for cardiovascular diseases (1105%). These data have been used to investigate comorbidities, off-target effects of medication, as well as assessing disease incidence and prevalence. Most papers published across all three domains were in journals with an impact factor less than 10.
    Keywords:  COPD; ILD; asthma; chronic obstructive pulmonary disease; electronic health records; interstitial lung disease
    DOI:  https://doi.org/10.2147/POR.S469973
  88. Bioscience. 2024 Jul;74(7): 473-477
      Scientific history has many examples of profound statements that are later found to be unsubstantiated. The consequences of such misinformation can be dire. In the present article, we present a case where an unevidenced estimate of global lichen coverage proliferated through both scientific literature and popular media. We traced this estimate to a non-peer-reviewed publication from 1987. We found 76 academic articles (collectively cited 4125 times) and 13 other academic documents citing the statistic, citation chains without source attribution, and instances where the number or context was changed. We also found the statistic 37 times in popular media, which is especially concerning, given that these media communicate science to the broader public. We demonstrate how an unevidenced statement can spread, change through time, and ultimately be repeated without demand for evidence. We hope this case unplugs the telephone and provides a cautionary tale for researchers to ensure critical evaluation of citation and communication practices.
    Keywords:  citation practices; global vegetation; science communication; terrestrial coverage
    DOI:  https://doi.org/10.1093/biosci/biae048
  89. Account Res. 2024 Aug 17. 1-19
       BACKGROUND: The study examines the prevalence of plagiarism in hijacked journals, a category of problematic journals that have proliferated over the past decade.
    METHODS: A quasi-random sample of 936 papers published in 58 hijacked journals that provided free access to their archive as of June 2021 was selected for the analysis. The study utilizes Urkund (Ouriginal) software and manual verification to investigate plagiarism and finds a significant prevalence of plagiarism in hijacked journals.
    RESULTS: Out of the analyzed sample papers, 618 (66%) were found to contain instances of plagiarism, and 28% of papers from the sample (n = 259) displayed text similarities of 25% or more. The analysis reveals that a majority of authors originate from developing and ex-Soviet countries, with limited affiliation ties to developed countries and scarce international cooperation in papers submitted to hijacked journals. The absence of rigorous publication requirements, peer review processes, and plagiarism checks in hijacked journals creates an environment where authors can publish texts with a significant amount of plagiarism.
    CONCLUSIONS: These findings suggest a tendency for fraudulent journals to attract authors who do not uphold scientific integrity principles. The legitimization of papers from hijacked journals in bibliographic databases, along with their citation, poses significant challenges to scientific integrity.
    Keywords:  Plagiarism; hijacked journals; scientific misconduct; 
    DOI:  https://doi.org/10.1080/08989621.2024.2387210