bims-evares Biomed News
on Evaluation of research
Issue of 2024–08–11
79 papers selected by
Thomas Krichel, Open Library Society



  1. World Neurosurg. 2024 Aug 02. pii: S1878-8750(24)01332-9. [Epub ahead of print]
       OBJECTIVE: The aim was to conduct a comprehensive bibliometric analysis of meningioma research, focusing on publication trends, top authors, universities, countries, and thematic analysis of keywords.
    METHODS: From Scopus databases, first we analyzed 23180 papers (or 19,824 articles and 3,356 reviews) published between 2001 and 2023. Second, we selected the top 100 most cited papers and descriptively analyzed on Vosviewer and R Studio (bibliometrix/biblioshiny).
    RESULTS: For both sets, we highlighted the annual publication trends and the impact of top-cited papers. We identified leading authors, universities, and countries contributing significantly to the field. Keywords analysis categorized research themes across all papers. Specific focus was given to the top 100 most cited documents in meningioma. Details about the annual number of papers, mean citations per year, and the citable years are provided. The top authors are presented by number of publications, citations, h-index, g-index and m-index. Co-words analysis was performed and the main focus of the 100 most cited papers are presented in more than 20 categories CONCLUSION: Our findings may provide insights into the evolution of meningioma research and its scholarly impact. The analysis underscores the pivotal contributions of top authors and institutions, outlines thematic research trends, and highlights areas of significant interest and growth in the field. Our study may contribute to understanding the landscape of meningioma research, guiding future research directions and collaborations.
    Keywords:  Bibliometric Analysis; Meningiomas; Scopus; Themes; Top Authors
    DOI:  https://doi.org/10.1016/j.wneu.2024.07.190
  2. Front Neurosci. 2024 ;18 1433583
       Background: Parkinson's disease (PD) is a prevalent neurodegenerative disorder affecting millions globally. It encompasses both motor and non-motor symptoms, with a notable impact on patients' quality of life. Electroencephalogram (EEG) is a non-invasive tool that is increasingly utilized to investigate neural mechanisms in PD, identify early diagnostic markers, and assess therapeutic responses.
    Methods: The data were sourced from the Science Citation Index Expanded within the Web of Science Core Collection database, focusing on publications related to EEG research in PD from 2004 to 2023. A comprehensive bibliometric analysis was conducted using CiteSpace and VOSviewer software. The analysis began with an evaluation of the selected publications, identifying leading countries, institutions, authors, and journals, as well as co-cited references, to summarize the current state of EEG research in PD. Keywords are employed to identify research topics that are currently of interest in this field through the analysis of high-frequency keyword co-occurrence and cluster analysis. Finally, burst keywords were identified to uncover emerging trends and research frontiers in the field, highlighting shifts in interest and identifying future research directions.
    Results: A total of 1,559 publications on EEG research in PD were identified. The United States, Germany, and England have made notable contributions to the field. The University of London is the leading institution in terms of publication output, with the University of California closely following. The most prolific authors are Brown P, Fuhr P, and Stam C In terms of total citations and per-article citations, Stam C has the highest number of citations, while Brown P has the highest H-index. In terms of the total number of publications, Clinical Neurophysiology is the leading journal, while Brain is the most highly cited. The most frequently cited articles pertain to software toolboxes for EEG analysis, neural oscillations, and PD pathophysiology. Through analyzing the keywords, four research hotspots were identified: research on the neural oscillations and connectivity, research on the innovations in EEG Analysis, impact of therapies on EEG, and research on cognitive and emotional assessments.
    Conclusion: This bibliometric analysis demonstrates a growing global interest in EEG research in PD. The investigation of neural oscillations and connectivity remains a primary focus of research. The application of machine learning, deep learning, and task analysis techniques offers promising avenues for future research in EEG and PD, suggesting the potential for advancements in this field. This study offers valuable insights into the major research trends, influential contributors, and evolving themes in this field, providing a roadmap for future exploration.
    Keywords:  CiteSpace; Parkinson’ disease; VOSviewer; bibliometrix; electroencephalogram; neural oscillations; visualization analysis
    DOI:  https://doi.org/10.3389/fnins.2024.1433583
  3. Environ Sci Pollut Res Int. 2024 Aug 06.
      Di-(2-ethylhexyl) phthalate (DEHP) is one of the most widely used plasticizers. Many studies focus on the impact of continuous exposure to DEHP on humans and ecosystems. In this study, the bibliometric analysis of DEHP and its metabolites research was conducted to assess the research performances, hotspot issues, and trends in this field. The data was retrieved from a Web of Science Core Collection online database. VOSviewer 1.6.18 was used to analyze. A total of 4672 publications were collected from 1975 to 2022 October 21. The number of publications and citations increased annually in the last decades. China had the largest number of publications, and the USA had the highest co-authorship score. The most productive and most frequently cited institutions were the Chinese Academy of Sciences and the Centers for Disease Control & Prevention (USA), respectively. The journal with the most publications was the Science of Total Environment, and the most cited one was the Environmental Health Perspectives. The most productive and cited author was Calafat A. M. (USA). The most cited reference was "Phthalates: toxicology and exposure." Four hotspot issues were as follows: influences of DEHP on the organisms and its possible mechanisms, assessment of DEHP exposure to the human and its metabolism, dynamics of DEHP in external environments, and indoor exposure of DEHP and health outcomes. The research trends were DNOP, preterm birth, gut microbiota, microplastics, lycopene, hypertension, and thyroid hormones. This study can provide researchers with new ideas and decision-makers with reference basis to formulate relevant policies.
    Keywords:  Bibliometric analysis; DEHP; Exposure; MEHP; Metabolites
    DOI:  https://doi.org/10.1007/s11356-024-34533-x
  4. Front Neurol. 2024 ;15 1443817
       Objectives: This study utilizes bibliometric analysis to map the current research landscape and forecast emerging trends within the domain of Burning Mouth Syndrome (BMS).
    Materials and methods: A comprehensive review of literature related to BMS was conducted, drawing from the Web of Science Core Collection (WoSCC) from 2008 to 2023. The analysis included both publication types "Article" and "Review Article." Advanced quantitative techniques and visual analytics tools, including CiteSpace, VOSviewer, Tableau, and the Map Equation online platform were utilized to analyze the academic publications within this domain.
    Results: Our analysis incorporated 497 articles on BMS. The data exhibit a progressive increase in the annual volume of publications from 2008 to 2023. In terms of geographic and institutional contributions, the United States of America (with 80 publications) and Nihon University (with 26 publications) emerged as leading entities in BMS research, while the Netherlands and England were identified as central to international collaboration efforts. Prominent researchers in this field include Adamo Daniela (18 publications) and Sun Andy (16 publications). Furthermore, the most cited works were authored by Jääskeläinen SK. An examination of the journals in which these articles were published showed a dominance of dental journals, highlighting significant interest and research efforts in BMS within the dental research community.
    Conclusion: The steady growth in BMS research signifies the formation of a robust core of researchers and demonstrates the maturation of the field. Despite this progress, the findings highlight a notable deficiency in cross-institutional and cross-regional collaborative efforts. Keyword cluster analysis has revealed "management" as a persistently relevant theme, with "pain modulation" emerging as the current focal interest. Additionally, "blood profile," "pernicious anemia," and "folate" have been identified as prospective areas of growing interest, suggesting important directions for future investigations.
    Clinical relevance: This bibliometric analysis reveals the research landscape of BMS, aiming to highlight potential collaborative opportunities and define future research directions. These insights are invaluable for guiding subsequent investigations and carving new paths in the exploration of BMS.
    Keywords:  CiteSpace; bibliometric analysis; burning mouth syndrome; research trends; visualization
    DOI:  https://doi.org/10.3389/fneur.2024.1443817
  5. Turk J Emerg Med. 2024 Jul-Sep;24(3):24(3): 145-150
       OBJECTIVES: Publications and literature related to emergency medicine (EM) have been consistently increasing. There are 4048 studies in total in the EM journals published until the present day in Türkiye in the Web of Science (WoS) database. Our aim is to define the bibliometric features of scientific studies published in EM journals in Türkiye, to gain insights into the trends of the literature.
    METHODS: We retrospectively analyzed the bibliometric data of scientific studies published in EM journals in Türkiye until today on the WoS database related to the EM field. The bibliometrix package of R statistical software was used in the bibliometric analyses in the study.
    RESULTS: A total of 4048 scientific studies from Türkiye indexed on the WoS database from 10,263 authors in four different journals were analyzed. Among these, 3681 (90.9%) were articles, 188 (4.7%) were reviews, 97 (2.4%) were editorial material, 60 (1.5%) were letters, and 5 (0.1%) were corrections. Average number of citations per study was 3.6, with the most cited study having 2016 citations. The most frequent title's words were emergency, patient, and acute.
    CONCLUSION: This study shows that there is an increasing trend in the number of EM publications and citations in Türkiye with the first most cited study having 2016 citations, and the top contributing countries were Türkiye, Iran, and India. The results of this study may be useful in understanding the historical and prospective development of EM, including the identification of general information about its publications, differentiation of the top-cited ones, and presentation of a bibliometric analysis of scientific activity to date.
    Keywords:  Bibliometric analysis; Türkiye; emergency medicine; publications
    DOI:  https://doi.org/10.4103/tjem.tjem_5_24
  6. Braz Oral Res. 2024 ;pii: S1806-83242024000107200. [Epub ahead of print]38 e075
      This study assessed the features of the 100 most-cited papers on diabetes mellitus (DM) in dentistry using bibliometric measures. A search of the most cited papers on DM using journals included in the category "Dentistry, Oral Surgery and Medicine" in the Web of Science database up to January 2023 was performed. The complete bibliographic records of the selected papers were exported in plain text or Research Information Systems (RIS) file format. The following bibliometric indicators were collected: title, year, authors, number of citations, mean number of citations, institution, country, continent, study design, journal, impact factor, and keywords. Graphical bibliometric networks were created using the VOSviewer software. The number of citations for the 100 most-cited papers in DM research ranged from 111 to 566. Six papers each had more than 400 citations. Most were observational studies (n = 50) from the United States (USA) (n = 23) and were published in the Journal of Periodontology (30%; n=30). Robert Genco was the most cited author and contributed the most to the top 100 articles (3,653 citations; n = 13). The VOSviewer map of co-authorship showed the existence of clusters in research collaboration. The most prolific institutions were the Universities of Buffalo and Michigan (n = 6 each). "Diabetes mellitus" was the most frequent keyword, with 31 occurrences. In conclusion, the most cited studies that investigated the relationship between dentistry and DM were in periodontology. Observational studies, primarily from the USA, have been the most cited thus far.
    DOI:  https://doi.org/10.1590/1807-3107bor-2024.vol38.0075
  7. Int J Med Sci. 2024 ;21(10): 1852-1865
      Background: Triggering receptor expressed in myeloid cells 2 (TREM2), a transmembrane receptor, has garnered extensive research attention due to its pivotal role in the diagnosis and treatment of various diseases. Despite the abundance of studies on its function, there is a gap in comprehensive analysis and summarization of the current state of this research field. Methods: Articles and reviews related to TREM2 were retrieved from the Web of Science Core Collection (WOSCC) on October 1, 2023. A bibliometric analysis of TREM2 was conducted using CiteSpace, VOSviewer and Bibliometrix (R package). Results: A total of 1,502 articles, spanning from 2001 to 2022, met the search criteria. The number of publications and citations has increased steadily over the years. The United States and China are the most active countries in TREM2 research, with the University of Washington as the leading research institution. The most influential journal in the field is Neurology of Aging. The predominant research areas include molecular, biology and immunology. Alzheimer's disease, microglia, variants, and inflammation are significant keywords. Emerging directions such as metabolism and tumor microenvironment have recently gained attention in numerous studies. Conclusion: The current study utilizes bibliometric analysis software and visual graphics to intuitively highlight TREM2-related hotspots, trends, and prospects in human disease. Such insights are valuable for scholars seeking a deeper understanding of TREM2-related research progress, enabling a focused approach to its application in human disease.
    Keywords:  Alzheimer's disease; CiteSpace; TREM2; VOSviewer; bibliometric analysis
    DOI:  https://doi.org/10.7150/ijms.96851
  8. Heliyon. 2024 Jul 30. 10(14): e34612
      The digital era is reshaping agricultural practices, opening new avenues for sustainable growth, and proving indispensable in global challenges like food security and environmental conservation. However, a comprehensive understanding of this evolving landscape remains paramount. This research evaluates 344 papers from the Web of Science database to delve into sustainable agriculture's historical and current patterns in the digital era through bibliometric analysis and project future domains. Specifically, citation analysis identified influential papers, journals, institutions, and countries, while co-authorship analysis verified the interactions between authors, affiliations, and countries. Co-citation analysis found four hotspot clusters: prosperity and challenges in agricultural sustainability, digital information and agricultural development, innovations for sustainable agriculture, and geospatial analysis in environmental studies. The co-occurrence of keywords analysis revealed four main clusters for future studies: smart agriculture and biodiversity conservation, digitalization and sustainable agriculture, technologies and agricultural challenge management, and digital intelligence and farmer adoption. The study pioneers the use of bibliometric analysis to explore sustainable agriculture in the digital era. It presents invaluable insights into the evolving landscape of this field, summarizing its hotspots and suggesting future trajectories.
    Keywords:  Bibliometric analysis; Digitization; Sustainable agriculture; Web of science
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e34612
  9. Clin J Am Soc Nephrol. 2024 Aug 06.
       BACKGROUND: Historically, women's scientific contributions have been under-recognized. We investigated whether the number of citations, a key metric used for academic promotions and scientific productivity, differs in nephrology high impact publications based on author's gender.
    METHODS: We identified randomized clinical trials (RCTs) from 2000-2021 in ten high impact journals. We assessed author gender, citations, h-index, m-index, years active publishing, education, and grant funding. The main predictor of interest was the gender of the first author. The main outcome was the standardized citation count for analysis of the selected publications. Additionally, we evaluated standardized author citation counts using the author, rather than paper.
    RESULTS: Among the selected publications, women were first authors of 65 (17.1%) and men of 315 manuscripts (82.9%). In crude analyses, publications with male first authors had a significantly higher median number of standardized citations (14 vs. 10, P=0.01). Adjusted analyses revealed, the m-index (β=29.48, P≤0.01) and journal impact factor (β=0.78, P<0.001) were significantly associated with the standardized citation index. In contrast, neither the gender of the first author (βmale gender=1.42, P=0.71) nor of the last author (βmale gender=8.89, P=0.38) were significantly associated with the standardized citations. Similarly, in adjusted analyses based on author profiles, male authorship was not significantly associated with the standardized author citation number (βmale gender=-7.79, P=0.08).
    CONCLUSIONS: Our study highlights marked disparities in the overall number of women publishing high impact nephrology trials and the number of papers with women scientists as first authors of high impact trials in the nephrology literature. Although crude citation rates were lower in papers with female first authors, the gender of the first author was not independently associated with citation metrics. Addressing gender disparities in academic recognition requires nuanced approaches extending beyond authorship and a broader focus on complex factors that influence academic recognition and scientific contributions.
    DOI:  https://doi.org/10.2215/CJN.0000000000000511
  10. Asian J Surg. 2024 Aug 07. pii: S1015-9584(24)01644-0. [Epub ahead of print]
       BACKGROUND: Follicular thyroid carcinoma (FTC), the second most prevalent thyroid cancer after papillary thyroid cancer (PTC), tends to metastasize distantly, leading to poorer outcomes. Despite substantial research, a holistic bibliometric analysis of FTC literature is lacking. This study aims to fill this gap by employing bibliometric methods to track FTC research evolution.
    METHODS: English FTC publications were systematically gathered from the Web of Science. Bibliometric analysis, using R, VOSviewer, CiteSpace, and Excel, synthesized data and explored global research trends and topics.
    RESULTS: From 2000 to 2023, 9086 authors from 1953 institutions across 75 countries contributed to 1776 papers in 491 academic journals on FTC. The last two decades have witnessed a steady increase in publications related to FTC, with the United States leading in terms of publication volume. The United States dominated both in publications and citations, with the National Cancer Institute and Sheue-Yann Cheng as leading contributors. The journal 'Thyroid' featured the most publications, while the 'Journal of Clinical Endocrinology and Metabolism' ranked highest in citation frequency. Research focused on gene expression analysis and preoperative diagnostics, with recent trends shifting toward prognosis management and machine learning due to advances in medical technology and increased health awareness.
    CONCLUSION: This comprehensive bibliometric analysis has mapped the landscape of FTC research, highlighting key contributors, institutions, and thematic trends. Current discourse predominantly revolves around genetic analysis, prognostic determinants, and preoperative diagnostics in FTC. This foundational work guides future FTC research, providing insights into its evolution.
    Keywords:  Bibliometric analysis; Follicular thyroid carcinoma; Hot spots; Trend; Web of science
    DOI:  https://doi.org/10.1016/j.asjsur.2024.07.271
  11. Medicine (Baltimore). 2024 Aug 09. 103(32): e39238
      The role of human microbiota in mental health and the underlying mechanisms of psychobiotics, which can modulate mood and behavior through the microbiota-gut-brain axis, has been a focus of scientific scrutiny. This work presents a bibliometric analysis to uncover research trends and insights in psychobiotics literature. The Clarivate Analytics Web of Science database served as the source for articles and reviews on psychobiotics spanning the years 2012 to 2023. Bibliometric network visualization and graphing were conducted using VOSviewer, Microsoft Excel for Windows 10, and Datawrapper software. A total of 348 publications were included, and it has been determined that the number of publications and citations shows an increasing trend from 2012 to 2023. The most active authors on psychobiotics, in order, were Dinan TG, Cryan JF, and Tsai YC. The most active organizations have been identified as University College Cork, National Yang Ming Chiao Tung University, and Bened Biomedical Co. Ltd. The most active countries in psychobiotic research were China, Ireland, and United States of America, while the most active journals were Nutrients, International Journal of Molecular Sciences, and Probiotics and Antimicrobial Proteins. The most commonly used keywords were "psychobiotics," "probiotics," and "gut-brain axis." This bibliometric analysis has revealed the growing academic interest in psychobiotics, indicating that the relationship between gut microbiota and mental health will increasingly be supported by scientific evidence in the years ahead.
    DOI:  https://doi.org/10.1097/MD.0000000000039238
  12. Medicine (Baltimore). 2024 Aug 09. 103(32): e39295
      Diabetic peripheral neuropathy (DPN) is a prevalent disease, and the relevant literature has been increasingly investigated over the past years. Consequently, it is imperative to conduct a scientific and comprehensive DPN research field bibliometric analysis. This study aims to summarize and visualize the literature distribution laws, the research hotspots, and the development trends in DPN using bibliometric methods. We searched all relevant documents published from 2011 to 2023 in the Web of Science Core Collection. Bibliometric analysis and network visualization were performed using VOSviewer, R-bibliometrix, and CiteSpace tools, focusing on countries, institutions, authors, journals, highly cited papers, references, and keywords. This study included a total of 2708 documents. The annual number of publications in the field has notably increased. China, the USA, and the UK take on critical significance in DPN research. The University of Manchester in the UK has the highest number of publications (109). Malik has the most publications (86). Tesfaye literature has been most frequently cited by scholars of DPN research. The Journal of Diabetes and its Complications and Frontiers in Endocrinology have the most publications (45 each). Diabetes Care stands out with the highest impact factor (16.200), number of citations (2516), and H-index (27) among the number of publications top 10 journals. The paper "Colloca, L. et al Neuropathic pain. Nature Reviews Disease Primers. 2017, 3 (1):1-19" has the highest number of citations (1224 times). The most critical co-cited reference is "Tesfaye S, 2010, DIABETES CARE, V33, P2285" (cited 408 times). Keywords like "type 2 diabetes," "diagnosis," "association," "retinopathy," "risk factors," "progression," "corneal confocal microscopy," "nephropathy," "balance," "microvascular complications," "inflammation," "disease," and "insulin resistance" represent the recent research hotspots. The development, research hotspots, and future trends of the global DPN domain from 2011 to 2023 were summarized and visualized in this study. This study can present more insights into the general situation of DPN research and provide a useful reference for clinical decision-making and directions of subsequent research.
    DOI:  https://doi.org/10.1097/MD.0000000000039295
  13. Medicine (Baltimore). 2024 Aug 09. 103(32): e39241
      This study is the first comprehensive bibliometric analysis about meningioma to date. The aim of this study is to identify the most influential publications in this field through citation and co-citation analysis, to examine international collaborations, to identify the conceptual framework of the subject and emerging trending topics through keyword analysis, and to identify the most productive countries, authors and journals. 9619 articles on meningioma published between 1980 and 2023 were downloaded from the Web of Science (WoS) database and statistically analyzed. In this study, various bibliometric techniques were utilized, including trend keyword analysis, thematic evolution analysis, factor analysis, conceptual structure analysis, citation and co-citation analyses. Bibliometric network visualization maps were created to identify trend topics, citation analysis and cross-country collaborations. The Exponential Smoothing estimator was used to predict article productivity in the coming years. The first 3 countries that contributed the most to the literature were respectively; USA (2664, 27.7%), Japan (972, 10.1%), Germany (943, 9.8%). The first three most productive journals were respectively; Journal of Neurosurgery (number of article = 496), World Neurosurgery (399), Acta Neurochirurgica (378). The most productive author was Mcdermott MW (number of article = 88) and the most active institution was the University of California System (number of article = 470). In addition to high-grade meningiomas, the most studied topics from past to present have been magnetic resonance imaging, recurrence, radiation therapy, and skull base. As a result of the analyses to determine trend topics, the subjects studied in recent years were diagnostic and imaging methods, surgical and treatment methods, prognosis and survival, epidemiology and quality of life, and with the advancement of technology, machine learning and prediction models. Scientific collaboration was seen primarily in articles from western countries, especially the USA, European countries, and Canada. However, there was also a not insignificant effect in developing countries such as China, India, and Turkey.
    DOI:  https://doi.org/10.1097/MD.0000000000039241
  14. J Med Internet Res. 2024 Aug 09. 26 e58950
       BACKGROUND: Digital health research plays a vital role in advancing equitable health care. The diversity of research teams is thereby instrumental in capturing societal challenges, increasing productivity, and reducing bias in algorithms. Despite its importance, the gender distribution within digital health authorship remains largely unexplored.
    OBJECTIVE: This study aimed to investigate the gender distribution among first and last authors in digital health research, thereby identifying predicting factors of female authorship.
    METHODS: This bibliometric analysis examined the gender distribution across 59,980 publications from 1999 to 2023, spanning 42 digital health journals indexed in the Web of Science. To identify strategies ensuring equality in research, a detailed comparison of gender representation in JMIR journals was conducted within the field, as well as against a matched sample. Two-tailed Welch 2-sample t tests, Wilcoxon rank sum tests, and chi-square tests were used to assess differences. In addition, odds ratios were calculated to identify predictors of female authorship.
    RESULTS: The analysis revealed that 37% of first authors and 30% of last authors in digital health were female. JMIR journals demonstrated a higher representation, with 49% of first authors and 38% of last authors being female, yielding odds ratios of 1.96 (95% CI 1.90-2.03; P<.001) and 1.78 (95% CI 1.71-1.84; P<.001), respectively. Since 2008, JMIR journals have consistently featured a greater proportion of female first authors than male counterparts. Other factors that predicted female authorship included having female authors in other relevant positions and gender discordance, given the higher rate of male last authors in the field.
    CONCLUSIONS: There was an evident shift toward gender parity across publications in digital health, particularly from the publisher JMIR Publications. The specialized focus of its sister journals, equitable editorial policies, and transparency in the review process might contribute to these achievements. Further research is imperative to establish causality, enabling the replication of these successful strategies across other scientific fields to bridge the gender gap in digital health effectively.
    Keywords:  JMIR Publications; Web of Science; algorithmic bias reduction; article; articles; author; authors; authorships; bibliometric; bibliometric analysis; comparative analysis; comparison; control group; digital health; diversity; equality; gender; gender distribution; gender gap; gender representation; journal; journals; medical informatics, authorship; scientometric; statistical analysis
    DOI:  https://doi.org/10.2196/58950
  15. Aesthet Surg J Open Forum. 2024 ;6 ojae053
       Background: Gluteoplasty or gluteal augmentation is a popular cosmetic procedure that is used to improve the volume, shape, and contour of the buttocks.
    Objectives: This bibliometric analysis aims to characterize emerging research trends and to assess the methodological quality of the highest impact gluteoplasty research.
    Methods: The 100 most-cited publications in gluteoplasty were identified on Web of Science, across all available journal years (from Inception to August 2023). Study details, including the citation count, main content focus, and outcome measures, were extracted and tabulated from each publication. Oxford Centre for Evidence Based Medicine level of evidence (LOE) of each study was assessed.
    Results: The 100 most-cited publications regarding gluteoplasty were cited by a total of 2375 publications. Citations per publication ranged from 5 to 176 (mean 23.75 ± 25.86), with the highest-cited study being authored by Simonacci, discussing autologous fat grafting (n = 176). Most publications were LOE 5 (n = 55), representative of the large number of case series and reports. The number of publications for LOE 1, 2, 3, and 4 was 1, 9, 13, and 22, respectively. The main content focus was "surgical technique" in 38 publications, followed by "outcomes" (n = 34) and "risk factors/prognosis" (n = 10). Patient-reported outcome measures (PROMs) were used in 20 publications, and 33 publications reported aesthetic outcome measures.
    Conclusions: This analysis demonstrates a need for improvement in research methodologies regarding gluteoplasty research. This advancement would be facilitated by robust, high-quality research through randomized control trials and multicenter studies, as well as the further development of validated PROMs for gluteoplasty.
    Level of Evidence 2:
    DOI:  https://doi.org/10.1093/asjof/ojae053
  16. Front Pharmacol. 2024 ;15 1418142
       Background: In recent years, with the rapid advancement of fundamental ultrasonography research, the application of ultrasound in disease treatment has progressively increased. An increasing body of research indicates that microbubbles serve not only as contrast agents but also in conjunction with ultrasound, enhancing cavitation effects and facilitating targeted drug delivery, thereby augmenting therapeutic efficacy. The objective of this study is to explore the current status and prevailing research trends in this field from 2009 to 2023 through bibliometric analysis and to forecast future developmental trajectories.
    Methods: We selected the Science Citation Index Expanded (SCI-Expanded) from the Web of Science Core Collection (WOSCC) as our primary data source. On 19 January 2024, we conducted a comprehensive search encompassing all articles and reviews published between 2009 and 2023 and utilized the bibliometric online analysis platform, CiteSpace and VOSviewer software to analyze countries/regions, institutions, authors, keywords, and references, used Microsoft Excel 2021 to visualize the trends of the number of articles published by year.
    Results: Between 1 January 2009, and 31 December 2023, 3,326 publications on ultrasound combined with microbubble therapy technology were included. There were a total of 2,846 articles (85.6%) and 480 reviews (14.4%) from 13,062 scholars in 68 countries/regions published in 782 journals. China and the United States emerged as the primary contributors in this domain. In terms of publication output and global institutional collaboration, the University of Toronto in Canada has made the most significant contribution to this field. Professor Kullervo Hynynen has achieved remarkable accomplishments in this area. Ultrasound in Medicine and Biology is at the core of the publishing of research on ultrasound combined with microbubble therapy technology. Keywords such as "sonodynamic therapy," "oxygen," "loaded microbubbles" and "Alzheimer's disease" indicate emerging trends in the field and hold the potential to evolve into significant areas of future investigation.
    Conclusion: This study provides a summary of the key contributions of ultrasound combined with microbubble therapy to the field's development over the past 15 years and delves into the historical underpinnings and contemporary trends of ultrasound combined with microbubble therapy technology, providing valuable guidance for researchers.
    Keywords:  bibliometric analysis; collaborative network; hot spots; microbubble; ultrasound
    DOI:  https://doi.org/10.3389/fphar.2024.1418142
  17. World J Diabetes. 2024 Jul 15. 15(7): 1627-1644
       BACKGROUND: Diabetic foot ulcers (DFUs) are one of the most severe and popular complications of diabetes. The persistent non-healing of DFUs is the leading cause of ampu-tation, which causes significant mental and financial stress to patients and their families. Macrophages are critical cells in wound healing and perform essential roles in all phases of wound healing. However, no studies have been carried out to systematically illustrate this area from a scientometric point of view. Although there have been some bibliometric studies on diabetes, reports focusing on the investigation of macrophages in DFUs are lacking.
    AIM: To perform a bibliometric analysis to systematically assess the current state of research on macrophage-related DFUs.
    METHODS: The publications of macrophage-related DFUs from January 1, 2004, to December 31, 2023, were retrieved from the Web of Science Core Collection on January 9, 2024. Four different analytical tools: VOSviewer (v1.6.19), CiteSpace (v6.2.R4), HistCite (v12.03.07), and Excel 2021 were used for the scientometric research.
    RESULTS: A total of 330 articles on macrophage-related DFUs were retrieved. The most published countries, institutions, journals, and authors in this field were China, Shanghai Jiao Tong University of China, Wound Repair and Regeneration, and Aristidis Veves. Through the analysis of keyword co-occurrence networks, historical direct citation networks, thematic maps, and trend topics maps, we synthesized the prevailing research hotspots and emerging trends in this field.
    CONCLUSION: Our bibliometric analysis provides a comprehensive overview of macrophage-related DFUs research and insights into promising upcoming research.
    Keywords:  Bibliometrics; Diabetic foot ulcers; Inflammation; Macrophage; Macrophage polarization; Wound healing
    DOI:  https://doi.org/10.4239/wjd.v15.i7.1627
  18. Front Immunol. 2024 ;15 1442027
       Background: Mitochondrial damage contributes to apoptosis, oxidative stress, and inflammation, which collectively impact the immune system's function and the tumor microenvironment (TME). These processes, in turn, influence tumor cell growth, migration, and response to treatment.
    Objective: We conducted a bibliometric analysis to elucidate the complex interactions between mitochondrial damage, the immune system, and the TME.
    Methods: Data were sourced from the Science Citation Index Core Collection (WoSCC) and analyzed using advanced tools like VOSviewer and Citespace. Our focus was on literature published between 1999 and 2023 concerning the interactions between mitochondrial damage and the TME, as well as immune responses to tumors. The analysis included regional contributions, journal influence, institutional collaborations, authorship, co-cited authors, and keyword citation bursts.
    Results: Our research encompassed 2,039 publications, revealing an increasing trend in annual output exploring the relationship between mitochondrial damage, TME dynamics, and immune responses. China, the United States, and South Korea emerged as the leading contributors. Prominent institutions included Institut National de la Santé et de la Recherche Médicale, University of Texas System, China Medical University, and Sun Yat-sen University. Key journals in this field are the International Journal of Molecular Sciences, Mitochondrion, and the European Journal of Pharmacology. Liang H and Wallace DC were identified as the most productive and co-cited authors, respectively. Keyword analysis highlighted the critical roles of inflammatory responses, oxidative stress, and the immune system in recent research.
    Conclusion: This bibliometric analysis provides a comprehensive overview of historical and current research trends, underscoring the pivotal role of mitochondrial damage in the TME and immune system.
    Keywords:  bibliometric analysis; immune response; mitochondrial damage; oxidative stress; tumor microenvironment
    DOI:  https://doi.org/10.3389/fimmu.2024.1442027
  19. World Neurosurg. 2024 Aug 05. pii: S1878-8750(24)01347-0. [Epub ahead of print]
       BACKGROUND: The subspecialized, clinically-complex nature of neurosurgery should not result in marginalization or under-representation of neurosurgical scientific output. This study aims to provide an overview of the trends of neurosurgical publications in high-impact medical journals during the past three decades.
    METHODS: An electronic database search was performed to identify all articles affiliated with neurosurgery departments published in 10 highly regarded medical journals. The trend of the proportion of neurosurgical publications to total publications in these journals was examined over time. Subgroup analyses based on location, setting, domain, grant source and topic of the articles were performed.
    RESULTS: Overall, 2,090 neurosurgical publications were identified in the selected journals, comprising 0.26% of those journals' publications. The proportion of neurosurgical publications to total publications in these journals increased over time, from 0.03% before 1991 to 0.35% after 2020. Most studies were single-center (82.7%), clinical (52.4%), and primary research (89%). The United States (40.1%), China (12.4%) and the UK (7.1%) had the highest number of neurosurgical publications among those analyzed. The share of clinical neurosurgical articles increased over time compared to basic and translational articles (p=0.01). Among neurosurgical subspecialties, neuro-oncology (60.1%), vascular (19.0%) and general (7.0%) had the highest number of publications identified, with substantial increases in vascular publications over time. The mean number of citations per year received by neurosurgical articles has increased over time, from 1.65 (before 1991) to 4.12 (2010-2020).
    CONCLUSIONS: Neurosurgery's proportion of high-impact journal publications has increased over time.
    Keywords:  Bibliometrics; High-impact; Medical Journals; Neurosurgery; Publications; Trend
    DOI:  https://doi.org/10.1016/j.wneu.2024.07.205
  20. Front Oncol. 2024 ;14 1383798
       Background: In recent years, with the continuous development of fluorescence imaging technology, research on its application in pancreatic diseases has surged. This area is currently of high research interest and holds the potential to become a non-invasive and effective tool in the diagnosis and treatment of pancreatic diseases. The objective of this study is to explore the hotspots and trends in the field of fluorescence imaging technology applications in pancreatic diseases from 2003 to 2023 through bibliometric and visual analysis.
    Methods: This study utilized the Web of Science (core collection) to identify publications related to the application of fluorescence imaging technology in pancreatic diseases from 2003 to 2023. Tools such as CiteSpace (V 6.2.R6), VOSviewer (v1.6.20), and R Studio (Bibliometrix: R-tool version 4.1.4) were employed to analyze various dimensions including publication count, countries, institutions, journals, authors, co-cited references, keywords, burst words, and references.
    Results: A comprehensive analysis was conducted on 913 papers published from January 1, 2003, to December 1, 2023, on the application of fluorescence imaging technology in pancreatic diseases. The number of publications in this field has rapidly increased, with the United States being the central hub. The University of California, San Diego emerged as the most active institution. "Biomaterials" was identified as the most influential journal. Authors with the most publications and the highest average citations per article are Hoffman, Robert M. and Luiken, George A., respectively. Keywords such as pancreatic cancer, cancer, expression, indocyanine green, and nanoparticles received widespread attention, with indocyanine green and nanoparticles being current active research hotspots in the field.
    Conclusion: This study is the first bibliometric analysis in the field of fluorescence imaging technology applications in pancreatic diseases. Our data will facilitate a better understanding of the developmental trends, identification of research hotspots, and direction in this field. The findings provide practical information for other scholars to grasp key directions and cutting-edge insights.
    Keywords:  ICG; bibliometric; fluorescence imaging technology; pancreatic diseases; trend
    DOI:  https://doi.org/10.3389/fonc.2024.1383798
  21. Front Pharmacol. 2024 ;15 1421499
      Melasma, a prevalent pigmentary disorder, is characterized by its complex etiology, propensity for recurrence, and resistance to treatment. However, there is currently no research on melasma through bibliometrics and visualisation. This study analyses the hotspots and trends in the field based on 2,709 publications from the Web of Science Core Collection (WOSCC). We carried out bibliometric analyses using Citespace software for different countries/regions, institutions, authors, and keywords. References were also analysed using VoSviewer. The results indicate that overall, there has been an increase in publications related to melasma since 2014. According to the analysis of the collaborative network diagram, the United States, Egyptian Knowledge Bank, and Benjakul Soottawat are the most contributing countries, institutions, and authors, respectively. Reference and keyword analyses have identified the pathogenesis and treatment of melasma as a prevalent topic in recent years. And how to find new treatment options and more effective therapeutic drugs is a future research trend. This is the first bibliometric and visual analysis of melasma-related literature to explore research hotspots and trends.
    Keywords:  bibliometric; globle research trends; melanosis; melasma; visualized study
    DOI:  https://doi.org/10.3389/fphar.2024.1421499
  22. Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug 09.
      Autophagy was considered to induce resistance in chemotherapy, which was significantly associated with proliferation of cancer; however, few bibliometric studies on the relation between autophagy and chemotherapy in lung cancer are available. The aim of the present study was to provide a comprehensive overview of the knowledge structure and research hotspots of autophagy and chemotherapy in lung cancer by bibliometric analysis. Publications related to autophagy and chemotherapy in lung cancer from 2003 to 2023 were searched on the Web of Science Core Collection (WoSCC) database. The bibliometric analysis was conducted by using VOSviewers, CiteSpace, and the R package "bibliometrix." A total of 675 articles from 70 countries, led by China and the United States, were included in the analysis. The number of publications related to autophagy and chemotherapy in lung cancer is increasing year by year. Nanjing Medical University, Zhejiang University, China Medical University, and Sichuan University are among the main research institutions contributing to this field. The journal Cancers is the most popular publication in this area, with Autophagy being the most co-cited journal. These publications involve 4481 authors, with Chiu Chien-chih and Gewirtz David having published the most papers, and Noboru Mizushima being the most frequently co-cited author. Studying the relation between autophagy and chemotherapy in the occurrence and development of lung cancer, and exploring therapeutic strategies involving autophagy and chemotherapy in lung cancer, are the primary topics in this research field. "Tumor stem cells," "microRNA," and "EGFR" emerge as the primary keywords in the emerging research hotspots. Indeed, this bibliometric study provides valuable insights into the research trends and developments concerning autophagy and chemotherapy in lung cancer. By identifying recent research frontiers and highlighting hot directions, this study serves as a valuable reference for scholars interested in understanding the relationship between autophagy and chemotherapy in lung cancer. The comprehensive summary of findings offers a foundation for further exploration and advancement in this critical area of cancer research.
    Keywords:  Autophagy; Bibliometrics; Chemotherapy; Lung cancer
    DOI:  https://doi.org/10.1007/s00210-024-03354-7
  23. Heliyon. 2024 Jul 30. 10(14): e34084
      Work-life balance has gained increasing popularity among scholars and practitioners since the beginning of the century. Despite significant attempts to consolidate this burgeoning field, the scholarly knowledge on work-life balance research remains fragmented and detached due to extant number of publications in the area and the mostly subjective approaches used to encapsulate the literature. As such, the current study presents an objective overview of work-life balance research between 2000 and 2020. Using bibliometric techniques, the authors examined 1190 articles indexed in Scopus database to identify the conceptual structure and current dynamics in the field. During the critical period between the reconceptualization of word-life balance and the emergence of COVID-19 pandemic, the findings reveal that the field was growing exponentially as a multidisciplinary research area. Most of the scholarly work originated in the US, UK, and Australia with a "locally-centralized-globally-discrete" collaboration pattern among scholars. The most relevant and developed research themes included, in addition to work-life balance, topics related to gender and family life. Furthermore, new emerging research directions had evolved beyond the traditional constructs including job security, flexible working hours, individual productivity, and work-life conflicts. The study contributes to the current knowledge on work-life balance by providing critical insights into the evolution of the field and offers potential avenues for scholars who are interested in this critical research domain and the changes it has experienced post pandemic.
    Keywords:  Bibliometric analysis; Co-citation networks; Keyword co-occurrence networks; Landscape mapping; Work-life balance
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e34084
  24. Medicine (Baltimore). 2024 Aug 09. 103(32): e39249
      In recent years, a surge in literature on psychological nurse resilience, largely driven by the COVID-19 pandemic, has prompted the need for a comprehensive understanding of the current state and emerging trends through reliable methodologies. The purpose of this study was to analyzes the research on nurses' psychological resilience through bibliometrics to understand the current situation, foundation, and hotspot of this research field. The Web of Science core collection database was used as the search source, and CiteSpace analysis software was employed to conduct bibliometric analysis on authors, countries, institutions, keywords, and references of nurse psychological resilience-related literature published from the establishment of the database to July 11, 2023. A total of 1060 articles were included in the final analysis. The study of nurses' psychological resilience had been highly popular and had formed a new and important research basis in recent years. China and the United States led in the number of publications and centrality respectively, with Monash Univ and Curtin Univ as top institutions in the number of publications and centrality respectively. The authors with the highest number of publications and the most frequently cited were Rees and Connor Km respectively. The most frequently cited article was Factors Associated with Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019 published by Lai, JB, etc. Important key keywords included mental health, resilience, stress, health, outbreak, acute respiratory syndrome, etc. The research topics in this field mainly focused on 4 aspects, including nurses' mental health, post-traumatic stress disorder, job burnout and job satisfaction, and intervention research on psychological resilience. The results of bibliometric analysis provide direct support for future scholars to explore and determine the research direction, hot spots, and find authoritative authors and institutions. At the moment, nurses' psychological resilience research has established a new foundation, primarily focusing on COVID-19-related topics. Given the potential prolonged coexistence of COVID-19 and other diseases, the main research focus remains innovating and validating effective psychological resilience intervention strategies for nurses' overall well-being.
    DOI:  https://doi.org/10.1097/MD.0000000000039249
  25. J Perianesth Nurs. 2024 Aug 07. pii: S1089-9472(24)00126-6. [Epub ahead of print]
       PURPOSE: Postoperative delirium (POD) is one of the most frequent complications after surgery which is closely associated with many adverse outcomes, including high mortality and low quality of life. This study aims to carry out a bibliometric analysis of POD and its risk factors from 2012 to 2022 to reveal the research status and hot spots.
    DESIGN: This study is a bibliometric and visualized analysis.
    METHODS: Relevant publications between 2012 and 2022 were extracted from the Web of Science Core Collection database. CiteSpace software (v6.1. R2, Drexel University), VOSviewer software (v1.6.18, Leiden University), and the Online Analysis Platform of Literature Metrology were used to analyze research attributes. These publications were used to analyze research attributes, including countries, journals, institutions, authors, keywords, and burst detection, to predict trends and hot spots.
    FINDINGS: We included a total of 1,324 related documents from 2012 to 2022. The literature on POD has increased significantly since 2016. The United States and Harvard University were the leading literature publishing country (436/1324, 32.9%) and institution (112/1324, 8.5%). Anesthesia and Analgesia was the most frequently published journal. Keywords analysis with VOSviewer revealed that the keywords could be divided into five clusters, including anesthesia techniques, cardiac surgery, risk factors, intraoperative anesthesia monitoring, and postoperative cognitive dysfunction. We included a total of 198 POD risk factors documents, and the literature on POD risk factors increased. The People's Republic of China and Harvard University were the leading literature publishing country (53/198, 26.8%) and institution (12/198, 6.1%). Elderly, hip surgery, frailty, postoperative pain, cardiac surgery, dementia, and depression are keywords that are risk factors for POD.
    CONCLUSIONS: The number of literature on POD in the field of anesthesia has increased significantly. Risk factors and anesthesia techniques are still key areas of research. Encephalogram, the use of sedatives, and perioperative nursing may be the new research focus. Older adults, hip fractures, cardiac surgery, liver transplants, dementia, and depression are hot words in the field of POD risk factors.
    Keywords:  bibliometrics; delirium; postoperative complication; risk factors
    DOI:  https://doi.org/10.1016/j.jopan.2024.04.002
  26. Medicine (Baltimore). 2024 Aug 09. 103(32): e39245
       BACKGROUND: The global spread of Coronavirus disease 2019 (COVID-19) has been increasing since December 2019. A total of 8460 publications were obtained from the Web of Science Core Collection from 2019 to 2023, providing insights into the progress of nursing research throughout the COVID-19 pandemic.
    METHODS: Bibliometric analysis was conducted on these articles using CiteSpace. The analysis focused on examining the distribution of these publications in terms of space and time, distribution of authors, subject categories, distribution of topics, and cited references.
    RESULTS: These results may be explained from 3 perspectives. Initially, the number of yearly publications on nursing research consistently increased during the COVID-19 pandemic. Furthermore, a co-occurrence analysis of the countries and the authors revealed that certain countries, including the United States, China, and England, have successfully implemented organized and standardized nursing models. These countries also have well-developed and established nursing research systems. Notably, academic communities in specific regions, such as the team led by MD Stefan Gravenstein, Mor Vincent, and White Elizabeth at Brown University in the United States, have emerged as leaders in this field. Furthermore, examining the papers' subject categories and topic distribution indicate that nursing during the COVID-19 pandemic has been predominantly interdisciplinary, encompassing various disciplines such as clinical medicine, essential medicine, psychology, public health management, and even telematics science.
    CONCLUSION SUBSECTIONGS: Our study provided valuable insights into acquiring knowledge on nursing research during the COVID-19 pandemic, pinpointed possible partners for researchers interested in nursing, and uncovered prevalent research patterns and popular subjects.
    DOI:  https://doi.org/10.1097/MD.0000000000039245
  27. Cureus. 2024 Jul;16(7): e63764
      Biomedical physics is the interdisciplinary field that links the scientific concepts in physics to the practice of medicine and biology, in an effort to understand biological processes, help in the development of medical technologies, to improve human health. This bibliometric study investigates the interdisciplinary field of biomedical physics, which integrates the principles of physics with biological and medical sciences to develop innovative diagnostic and therapeutic technologies. Utilizing the Web of Science database for bibliographic data collection, the analysis employs advanced bibliometric software tools, including Biblioshiny and VOSviewer, to comprehensively map the research landscape. Our findings delineate the annual scientific production, highlighting growth trends and identifying the most influential authors and key publication venues in the field. A thematic analysis reveals prevailing research topics and the evolution of scientific interests over time, providing insights into the shifting focus areas within biomedical physics. The factorial analysis goes further to clarify the conceptual structure of the discipline by providing a topological image of how the different research areas are involved. It helps to recognize topical fields and the possibility of the topicalization of other subjects. Keyword co-occurrence assumes the leading themes and measures the value of the topology. Meanwhile, bibliographical information defines the authors' network, and co-citation analysis identifies the critical authors' pool. The last points to the topic dependence and the network of research collaboration on a global scale. As a result, a survey identifies the deficits and rules of recommendations for the further development of research. It adds practical implications that are necessary for the development and identifies influences for popularization that it might have in the future.
    Keywords:  bibliometric analyses; bibliometric review; biblioshiny; biomedical physics; vosviewer
    DOI:  https://doi.org/10.7759/cureus.63764
  28. Mhealth. 2024 ;10 23
       Background: Mobile health (m-Health) is widely acknowledged as a pivotal domain for improving global healthcare and driving its digital health transformation. Despite the vast amount of literature published in recent years, bibliometric studies on m-Health remain limited in scope and coverage. This study presents a comprehensive review of m-Health literature extracted from Scopus and PubMed databases, spanning the period from 1997 to 2023, including publications during the coronavirus disease 2019 (COVID-19) pandemic.
    Methods: The combined Scopus and PubMed databases were used in this study. The search formula for the literature retrieval used the most appropriate and relevant keywords to m-Health. The bibliometric data importation, extraction and analysis of authors, titles, publication date, publication place, publisher, volume number, issue number, citation count, document type, author keywords, affiliation were all carried out using the 'Biblioshiny', 'EndNote X9®', 'Microsoft Excel®' and 'Microsoft Access®' software tools. Duplicate records were manually identified and removed. Visualization maps illustrating the recurrent keywords, collaboration patterns, and prolific publishing countries were generated using 'VOSviewer®'.
    Results: A total of 37,470 (20,703 from Scopus and 16,767 from PubMed) publications were selected for the literature analysis. The results provided the definitive literature evidence on the origin of the concept of m-Health in 2003. Significant increase in the publications followed the global surge of smart phones usage in 2007, and the emergence of m-Health applications (Apps) and their global markets and ecosystems. The number of the publications peaked between 2013 and 2022 with most citations in 2022. There was noticeable spike in m-Health literature during the COVID-19 pandemic. The results also showed that most of the highly cited publications, leading institutions, and most prolific authors were predominantly from the developed countries. The USA has the highest number of publications followed by the UK, Australia, Germany, Canada and China, with most of the prolific authors originating from these countries.
    Conclusions: In conclusion, while there has been a remarkable increase in global m-Health publications since 2003, most of the impactful literature and publications in this area originated from selected countries in the developed world. The study indicates a significant disparity between the published literature from developed compared to the developing countries. Addressing this disparity, further bibliographical studies are required to address these and other literature gaps.
    Keywords:  Mobile health (m-Health); bibliometric; digital health; telemedicine
    DOI:  https://doi.org/10.21037/mhealth-23-20
  29. Heliyon. 2024 Jul 30. 10(14): e34462
      Plant-derived natural compounds are significant resources for the discovery of potential anticancer drugs. While research in the plant-based anticancer field has surged in recent years, systematic bibliometric analyses covering a longer period and containing up-to-date publications remain scarce. Here, we conducted a bibliometric analysis of literature on the anticancer properties of plant natural compounds over the past three decades, leveraging the bibliometric framework and open-access platform, KNIME. Our findings showed that the number of plant anticancer-related publications underwent an accelerating growth from 1992 to 2023. The country and institution analyses revealed that countries with traditional medical systems contributed a large portion of publications in the plant anticancer field, such as India, China, and South Korea. This study also highlighted the top ten eminent researchers and publications, assisting researchers in identifying pivotal literature. The primary publications were domains of chemistry and biology-related fields, such as Pharmacology & Pharmacy, Plant Sciences, and Biochemistry & Molecular Biology. Additionally, we noted that flavonoids have been focal plant compounds in anticancer, with strong anticancer potential. Our study provides new insights into the progress and trends in the plant anticancer field and will assist researchers in grasping the future research direction.
    Keywords:  Anticancer; Bibliometric analysis; KNIME; Medicinal plants; Natural compounds
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e34462
  30. J Comp Pathol. 2024 Aug 07. pii: S0021-9975(24)00272-X. [Epub ahead of print]213 59-72
      The chicken embryo chorioallantoic membrane (CAM) model has played a crucial role in various aspects of cancer research. The purpose of this study is to help researchers clarify the research direction and prospects of the CAM model. A bibliometric analysis was conducted on the top 100 most cited articles on use of the CAM model in tumour research, retrieved from the Web of Science Core Collection database. Tools such as Bibliometrix, VOSviewer, CiteSpace and Excel were utilized for the visualization network analysis. The 100 articles analysed were mainly from the USA, China and European countries such as Germany and France. Tumour research involving CAM model experiments demonstrated reliability and scientific rigor (average citation count = 156.2). The analysis of keywords, topics and subject areas revealed that the applications of this model ranged from the biological characteristics of tumours to molecular mechanisms and signaling pathways, to recent developments in nanotechnology and clinical applications. Additionally, nude mouse experiments have been more frequently performed in recent years. We conclude that the CAM model is efficient, simple and cost-effective, and has irreplaceable value in various aspects of cancer research. In the future, the CAM model can further contribute to nanotechnology research.
    Keywords:  bibliometrics; chicken embryo chorioallantoic membrane model; development trends; tumour research
    DOI:  https://doi.org/10.1016/j.jcpa.2024.07.001
  31. Front Aging Neurosci. 2024 ;16 1380851
       Background: ET, one of the most prevalent neurological disorders, presents a significant challenge in terms of disability. Despite the growing focus on ET in recent years, comprehensive bibliometric analysis has been lacking.
    Methods: This study delves into essential tremor research covering the period from 2013 to 2023, utilizing the Web of Science (WOS) database. Employing CiteSpace for quantitative analysis, it examines an array of metrics including annual publication trends, contributions from countries and institutions, authorship patterns, key terminologies, and patterns of reference co-citation. The primary objective is to use CiteSpace for a detailed visual exploration of the literature over the last decade, pinpointing the evolving landscape and key areas of focus in essential tremor research, and thus providing a foundation for future investigative endeavors.
    Results: There were 2,224 literary works included in all. The amount of published works has been steadily rising in recent years. Of them, the majority originate from the United States, Louis, Elan D. is the publisher of the most publications (161 articles), and Movement Disorders is the journal that receives the most citations. The key words contribution and co-cited literatures suggest that the main research hotspots in recent years are the physiological and pathological mechanism of essential tremor, the determination of optimal targets for deep brain stimulation (DBS) and surgery transcranial magnetic resonance-guided focused ultrasound (MRgFUS) in the surgical management of essential tremor and the innovative research of botulinum toxin administration method.
    Keywords:  Citespace; emerging trends; essential tremor; knowledge graph; visualization
    DOI:  https://doi.org/10.3389/fnagi.2024.1380851
  32. Healthcare (Basel). 2024 Jul 27. pii: 1493. [Epub ahead of print]12(15):
      The proportion of aged populations is increasing worldwide. Exercise has a palliating effect on some adverse implications of aging. Multicomponent training (MCT) is a recommended form of exercise for the aged population. The aims of this research were to (1) study the number of publications regarding MCT in the aged population following an exponential growth rate; (2) identify the journals, authors, and countries that stand out the most in this area; and (3) describe the most common themes and used keywords in this field. The analysis was performed through the traditional laws of bibliometrics, including, Price's, Lotka's, Bradford's, and Zipf's law. All documents published in journals indexed in the Web of Science (WoS) Core Collection from 2001 to November 2023 that met the inclusion criteria were included. The 485 documents included in this review revealed that the number of annual publications experienced an exponential growth phase, 15 journals with six or more publications formed the core journals on this topic, and the author Mikel Izquierdo and his collaborative network topped the lists of prominent and prolific co-authors. Spain was the leading country in number of publications. Various thematic lines and keywords regarding strength, sarcopenia, quality of life, falls, balance, dual-task exercise, and cognitive and physical functioning were identified. In conclusion, this work confirmed that research on this topic is going through an exponential growth phase and provided detailed information about the journals, authors, and countries involved in the subject, as well as the keywords most frequently used in the subject matter.
    Keywords:  multicomponent exercise; older adults; physical functional performance; scientometrics
    DOI:  https://doi.org/10.3390/healthcare12151493
  33. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2377846
      
    Keywords:  Vaccines; antigen; atherosclerosis; bibliometrics; comment; research hotspots; research trends
    DOI:  https://doi.org/10.1080/21645515.2024.2377846
  34. Eur J Cardiothorac Surg. 2024 Aug 07. pii: ezae297. [Epub ahead of print]
       OBJECTIVES: To estimate gender disparities among first and last authorships in cardiothoracic randomized controlled trials(RCTs) and association of gender with publications in high impact journals.
    METHODS: PubMed/MEDLINE database was searched from January 1st , 2014-December 31st , 2020 using R statistical software via "easyPubMed" package to retrieve pertinent data. The "gender" package was utilized to determine gender using the United States Social Security Administration Baby Name Data. The percentage of women first and last authors were computed along with determining the uniqueness of the names. The association of gender and publication in high impact peer-reviewed journals was delineated. Jonckheere'e trend was computed.
    RESULTS: The database search retrieved total of 4820 RCTs. Of which, gender was encoded for first author of 3247 [67%] RCTs, among which 911[28%] studies had women as first authors with a similar trend across seven years [P value 0.23]. Gender was encoded for last author of 3204 [66%] RCTs, of which 622 [19%] studies had women as last authors with a similar trend across seven years [P value 0.45]. A total of 627 studies were published in high impact factor journals, among which 79[16%] studies had women first authors and 67[13%] studies had women last authors.
    CONCLUSIONS: There is an obvious gender disparity of first and last authors in cardiothoracic surgery related RCTs with a similar trend across seven years. However, the post-hoc analysis did demonstrate a positive trend with increase in the number of female first authors demonstrating progress.
    Keywords:  authorship; cardiothoracic; disparity; gender
    DOI:  https://doi.org/10.1093/ejcts/ezae297
  35. Nanomedicine (Lond). 2024 Jul 02. 19(16): 1449-1469
      Aim: To identify hotspots in this field and provide insights into future research directions. Methods: Publications were retrieved from the Web of Science Core Collection database. R Bibliometrix software, VOSviewer and CiteSpace were used to perform the bibliometric and visualization analyses. Results: The analysis comprised 468 publications from 58 countries, with the United States, China and India being the leading contributors. 'Gene therapy', 'nanoparticles' and 'insulin therapy' are the primary focuses. 'Green synthesis', 'cytotoxicity', 'bioavailability' and 'diabetic foot ulcers' have gained prominence, signifying high-intensity areas of interest expected to persist as favored research topics in the future. Conclusion: This study delves into recent frontiers and topical research directions and provides valuable references for further research in this field.
    Keywords:  bibliometrics; diabetes mellitus; green synthesis; insulin therapy; nanoparticles
    DOI:  https://doi.org/10.1080/17435889.2024.2358741
  36. Environ Sci Pollut Res Int. 2024 Aug 05.
      Inadequate management and treatment of wastewater pose significant threats, including environmental pollution, degradation of water quality, depletion of global water resources, and detrimental effects on human well-being. Biogranulation technology has gained increasing traction for treating both domestic and industrial wastewater, garnering interest from researchers and industrial stakeholders alike. However, the literature lacks comprehensive bibliometric analyses that examine and illuminate research hotspots and trends in this field. This study aims to elucidate the global research trajectory of scientific output in biogranulation technology from 1992 to 2022. Utilizing data from the Scopus database, we conducted an extensive analysis, employing VOSviewer and the R-studio package to visualize and map connections and collaborations among authors, countries, and keywords. Our analysis revealed a total of 1703 journal articles published in English. Notably, China emerged as the leading country, Jin Rencun as the foremost author, Bioresource Technology as the dominant journal, and Environmental Science as the prominent subject area, with the Harbin Institute of Technology leading in institutional contributions. The most prominent author keyword identified through VOSviewer analysis was "aerobic granular sludge," with "sequencing batch reactor" emerging as the dominant research term. Furthermore, our examination using R Studio highlighted "wastewater treatment" and "sewage" as notable research terms within the field. These findings underscore a diverse research landscape encompassing fundamental aspects of granule formation, reactor design, and practical applications. This study offers valuable insights into biogranulation potential for efficient wastewater treatment and environmental remediation, contributing to a sustainable and cleaner future.
    Keywords:  Bibliometric mapping; Environmental remediation; Granular development; Wastewater treatment
    DOI:  https://doi.org/10.1007/s11356-024-34550-w
  37. J Med Internet Res. 2024 Aug 08. 26 e57830
       BACKGROUND: With the rise of artificial intelligence (AI) in the field of dementia biomarker research, exploring its current developmental trends and research focuses has become increasingly important. This study, using literature data mining, analyzes and assesses the key contributions and development scale of AI in dementia biomarker research.
    OBJECTIVE: The aim of this study was to comprehensively evaluate the current state, hot topics, and future trends of AI in dementia biomarker research globally.
    METHODS: This study thoroughly analyzed the literature in the application of AI to dementia biomarkers across various dimensions, such as publication volume, authors, institutions, journals, and countries, based on the Web of Science Core Collection. In addition, scales, trends, and potential connections between AI and biomarkers were extracted and deeply analyzed through multiple expert panels.
    RESULTS: To date, the field includes 1070 publications across 362 journals, involving 74 countries and 1793 major research institutions, with a total of 6455 researchers. Notably, 69.41% (994/1432) of the researchers ceased their studies before 2019. The most prevalent algorithms used are support vector machines, random forests, and neural networks. Current research frequently focuses on biomarkers such as imaging biomarkers, cerebrospinal fluid biomarkers, genetic biomarkers, and blood biomarkers. Recent advances have highlighted significant discoveries in biomarkers related to imaging, genetics, and blood, with growth in studies on digital and ophthalmic biomarkers.
    CONCLUSIONS: The field is currently in a phase of stable development, receiving widespread attention from numerous countries, institutions, and researchers worldwide. Despite this, stable clusters of collaborative research have yet to be established, and there is a pressing need to enhance interdisciplinary collaboration. Algorithm development has shown prominence, especially the application of support vector machines and neural networks in imaging studies. Looking forward, newly discovered biomarkers are expected to undergo further validation, and new types, such as digital biomarkers, will garner increased research interest and attention.
    Keywords:  AI; artificial intelligence; bibliometric analysis; biomarker; dementia; machine learning
    DOI:  https://doi.org/10.2196/57830
  38. Complement Ther Med. 2024 Aug 05. pii: S0965-2299(24)00058-X. [Epub ahead of print] 103070
       OBJECTIVE: Post-stroke depression (PSD) is a prevalent and severe sequela of stroke. It is an emotional disorder that significantly impacts functional recovery, prognosis, secondary stroke risk, and mortality among stroke survivors. The incidence rate of PSD is 18%~33%, with symptoms such as low mood, decreased interest, sleep disorders, decreased appetite, impaired attention, and in severe cases, hallucinations and even suicidal tendencies. While diverse therapeutic modalities are employed globally to address PSD, each approach carries its inherent advantages and limitations. Notably, acupuncture stands out as a promising and effective intervention for ameliorating PSD symptoms and enhancing stroke prognosis. This study aims to conduct a bibliometric analysis to scrutinize the current landscape, identify hotspots, and explore frontiers in acupuncture research for PSD.
    METHODS: A systematic search for acupuncture and PSD-related research was conducted from January 2014 to October 2023 on the Web of Science Core Collection (WoSCC). The data were downloaded and processed using Bibliometrix and VOSviewer to generate knowledge visualization maps.
    RESULTS: A total of 11,540 articles related to acupuncture and PSD were retrieved. China emerged as the leading contributor with the highest volume of articles on acupuncture and PSD. Author Liu CZ attained the highest H-index, focusing primarily on investigating the compatibility effects and mechanisms of acupoints. Common hotspot keywords included pain, stimulation, mechanisms, complementary, and alternative medicine. The main research frontiers were mechanisms, neuroinflammation, gut microbiota, and therapeutic methods.
    CONCLUSION: This study offered multifaceted insights into acupuncture for PSD, unveiling pivotal areas, research hotspots, and emerging trends. The findings aimed to guide researchers in exploring novel research directions and selecting appropriate journals for advancing the understanding and treatment of PSD through acupuncture interventions.
    Keywords:  Acupuncture; Bibliometric analysis; Post stroke depression; Research direction; VOSviewer
    DOI:  https://doi.org/10.1016/j.ctim.2024.103070
  39. Zhongguo Zhen Jiu. 2024 Aug 12. 44(8): 975-82
      To explore the research hotspot, development trend and existing problem of artificial intelligence (AI) application in the field of acupuncture and moxibustion by using bibliometric method. Relevant articles of AI application in the field of acupuncture and moxibustion published in CNKI, Wanfang, VIP, PubMed and Web of Science from the database establishment to September 17, 2023 were searched. Excel 2019, CiteSpace 6.2.R4 and VOSviewer 1.6.19 were used to draw visual map of the number of publication, authors, research institutions and keywords, and further analyzed the research hotspot and trend. A total of 443 Chinese articles and 68 English articles were included. The number of annual publication of Chinese articles showed an overall increasing trend, while the number of publication of English articles was less, with a growing trend from 2020. Keywords analysis showed that "Machine learning", "neural network", "deep learning", "data mining", "robot" and other AI technologies were developing around acupuncture and moxibustion diagnosis and treatment of disease, efficacy prediction, teaching and intelligent equipment development. However, the research on the application of AI in the field of acupuncture and moxibustion is in the preliminary stage of development, and in the future, it is necessary to strengthen the communication and cooperation among the teams, to further explore the AI system in line with the characteristics of acupuncture and moxibustion diagnosis and treatment, and to promote the development of the digitalisation, intellectualisation and industrialisation of acupuncture and moxibustion.
    Keywords:  CiteSpace; VOSviewer; acupuncture and moxibustion; artificial intelligence; bibliometric
    DOI:  https://doi.org/10.13703/j.0255-2930.20231128-k0007
  40. Heliyon. 2024 Jul 30. 10(14): e34479
      Geological sequestration of carbon dioxide is a critical strategy to combat global warming, playing a significant role in the reduction of greenhouse gas emissions and preservation of the global ecosystem. Over more than three decades, this domain has expanded to encompass myriad research avenues and nuanced sub-fields. Proficiency in navigating the dynamic developments and prominent challenges in this arena is imperative for promoting scholarly advancement. In this investigation, bibliometric techniques are applied to perform a comprehensive qualitative and quantitative investigation of the progression of studies on CO2 geological sequestration. The analysis incorporates a thorough review and synthesis of the accumulated literature, comprising 34,392 articles sourced from the Web of Science Core Collection. The assessment primarily scrutinizes the chronological dispersal of research outputs, geographical and institutional representation, principal journals of publication, and patterns of authorship to highlight burgeoning areas of concentrated research endeavors and prospective future research frontiers. The data reveals a pronounced surge in academic literature focusing on CO2 geological storage post-2009, which underscores the increasing value of this research sector. Investigations of CO2 geological sequestration are characterized by widespread international engagement, with notable contributions from the United States, China, and the United Kingdom substantially steering the research discourse. The core investigative themes comprise comprehensive inquiries into the physical and chemical dynamics of CO2 containment, environmental repercussions, safety assessments, evaluation methods, and technological assessments of carbon storage, along with stringent scrutiny of geological contexts for their viability and efficacy as sequestration sites.
    Keywords:  Bibliometrics; CO2 geological storage; Knowledge mapping; Visualization
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e34479
  41. J Pharm Anal. 2024 Jul;14(7): 100948
      Skin flaps are frequently employed in plastic and reconstructive surgery to address tissue defects. However, their low survival rates remain a challenge, attributed to vascular crisis and necrosis. Despite numerous studies investigating drugs to alleviate flap necrosis, a comprehensive analysis of the research trend in this critical area is lacking. To gain a deeper understanding of the current status, research focal points, and future trends in drugs aimed at enhancing flap survival, a thorough retrospective analysis is imperative. This study aims to employ bibliometric methods to scrutinize the evolution, mechanisms, and forthcoming trends of drugs targeting flap survival improvement. Using VOSviewer software, we quantitatively and visually depict 1) annual temporal trends in the number of documents and citations; 2) national/regional publications and their collaborations; 3) institutional and authors' contribution; 4) journal contribution and relevance; and 5) analysis of research hotspots and directions derived from keywords. Ultimately, we discussed the prospects and challenges of future advances and clinical translation of drugs designed to enhance skin flap survival. In conclusion, the field of pharmacology dedicated to improving skin flap survival is expanding, and this study aims to offer a fresh perspective to promote the advancement and clinical application of such drugs.
    Keywords:  Bibliometric analysis; Drug therapy; Global trends; Skin flap
    DOI:  https://doi.org/10.1016/j.jpha.2024.02.002
  42. J Orthop. 2024 Dec;58 96-101
       Introduction: The present investigation examined the trend of publications and ranking in Orthopaedics and Sports Medicine of European countries during the years 1996 to 2022 and compared these with all the regions globally.
    Methods: In September 2023, the SCOPUS data of publications in Orthopaedics and Sports Medicine from the SCImago Journal & Country Rank website were retrieved. All the data from Western and Eastern Europe were extracted from the overall data of the global countries and merged into Excel files, for each of the years 1996-2022 and 2022.
    Results: Western European countries contributed significantly to the global share of publications in Orthopaedics and Sports Medicine with nearly 1/3rd of the total publications. Eastern European countries' contribution was minimal to the global publications and was almost 10 times less than the Western European countries. The total number of publications in the area of Orthopaedics and Sports Medicine from 1996 to 2022 at the European scale was led by the United Kingdom (N = 51510) and has maintained its supremacy until recently, in 2022. Amongst Western European countries, during the cumulative period of 1996-2022, the maximum contributions were made by the United Kingdom (N = 51510), and also in 2022, the United Kingdom contributed maximally (N = 3339). In the cumulative period of 1996-2022, Poland contributed maximally (N = 4049) among the Eastern European countries. In 2022, the maximum contribution from the Eastern European countries came from the Russian Federation (N = 462).
    Conclusion: The European continent is the major contributor to Orthopaedics and Sports Medicine research and publications, with almost 1/3rd of the global share of publications. Western European countries are far ahead in their contributions than Eastern European countries.
    Keywords:  Bibliometrics; Europe; Orthopaedics; SCImago journal and country rank; Sports medicine
    DOI:  https://doi.org/10.1016/j.jor.2024.07.002
  43. Digit Health. 2024 Jan-Dec;10:10 20552076241271722
       Objective: Current studies lack a comprehensive understanding of the environmental factors influencing type 2 diabetes, hindering an in-depth grasp of the overall etiology. To address this gap, we utilized network science tools to highlight research trends, knowledge structures, and intricate relationships among factors, offering a new perspective for a profound understanding of the etiology.
    Methods: The Web of Science database was employed to retrieve documents relevant to environmental risk factors in type 2 diabetes from 2012 to 2024. Bibliometric analysis using Microsoft Excel and OriginPro provided a detailed scientific production profile, including articles, journals, countries, and authors. Co-occurrence analysis was employed to determine the collaboration state and knowledge structures, utilizing social network tools such as Gephi, Tableau, and R Studio. Additionally, theme evolutionary analysis was conducted using SciMAT to offer insights into research trends.
    Results: The publications and themes related to environmental factors in type 2 diabetes have consistently risen, shaping a well-established research domain. Lifestyle environmental factors, particularly diet and nutrition, stand out as the most represented and rapidly growing topics. Key focal hotspots include sedentary and digital behavior, PM2.5, ethnicity and socioeconomic status, traffic and greenspace, and depression. The theme evolutionary analysis revealed three distinct paths: (1) oxidative stress-air pollutants-PM2.5-air pollutants; (2) calcium-metabolic syndrome-cardiovascular disease; and (3) polychlorinated biphenyls (PCBs)-persistent organic pollutants (POPs)-obesity.
    Conclusions: Digital behavior signifies a novel approach for preventing and managing type 2 diabetes. The influence of PM2.5 and calcium on oxidative stress and abnormal vascular contraction is intricately linked to microvascular diabetes complications. The transition from PCBs and POPs to obesity underscores the disruption of endocrine function by chemicals, elevating the risk of diabetes. Future studies should explore the connections between environmental factors, microvascular complications, and long-term outcomes in diabetes.
    Keywords:  Bibliometric analysis; environmental factors; evolutionary analysis; knowledge mapping; social network analysis; type 2 diabetes
    DOI:  https://doi.org/10.1177/20552076241271722
  44. Health Res Policy Syst. 2024 Aug 06. 22(1): 96
       BACKGROUND: Cancer is a major public health challenge globally. However, little is known about the evolution patterns of cancer research communities and the influencing factors of their research capacity and impact, which is affected not only by the social networks established through research collaboration but also by the knowledge networks in which the research projects are embedded.
    METHODS: The focus of this study was narrowed to a specific topic - 'synthetic lethality' - in cancer research. This field has seen vibrant growth and multidisciplinary collaboration in the past decade. Multi-level collaboration and knowledge networks were established and analysed on the basis of bibliometric data from 'synthetic lethality'-related cancer research papers. Negative binomial regression analysis was further applied to explore how node attributes within these networks, along with other potential factors, affected paper citations, which are widely accepted as proxies for assessing research capacity and impact.
    RESULTS: Our study revealed that the synthetic lethality-based cancer research field is characterized by a knowledge network with high integration, alongside a collaboration network exhibiting some clustering. We found significant correlations between certain factors and citation counts. Specifically, a leading status within the nation-level international collaboration network and industry involvement were both found to be significantly related to higher citations. In the individual-level collaboration networks, lead authors' degree centrality has an inverted U-shaped relationship with citations, while their structural holes exhibit a positive and significant effect. Within the knowledge network, however, only measures of structural holes have a positive and significant effect on the number of citations.
    CONCLUSIONS: To enhance cancer research capacity and impact, non-leading countries should take measures to enhance their international collaboration status. For early career researchers, increasing the number of collaborators seems to be more effective. University-industry cooperation should also be encouraged, enhancing the integration of human resources, technology, funding, research platforms and medical resources. Insights gained through this study also provide recommendations to researchers or administrators in designing future research directions from a knowledge network perspective. Focusing on unique issues especially interdisciplinary fields will improve output and influence their research work.
    Keywords:  Cancer research; Collaboration network; International collaboration; Knowledge network; Paper citations; Research capacity and impact; Synthetic lethality
    DOI:  https://doi.org/10.1186/s12961-024-01205-8
  45. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2386223
      
    Keywords:  CAR-T; Hematological malignancies; bibliometric analysis
    DOI:  https://doi.org/10.1080/21645515.2024.2386223
  46. Front Res Metr Anal. 2024 ;9 1385080
      
    Keywords:  citations; metric abuse; original research; perspectives; research community; reviews; scientific reputation
    DOI:  https://doi.org/10.3389/frma.2024.1385080
  47. An Acad Bras Cienc. 2024 ;pii: S0001-37652024000501201. [Epub ahead of print]96(3): e20230789
      Artificial intelligence tools are new in taphonomy and are growing fast. They are being used mainly to investigate bone surface marks. In order to investigate this subject, a bibliometric study was made to understand the growing rate of this intersectional field, the future, and gaps in the field until now. From Scopus and Google Scholar metadata, graphs were made to describe the data, and inferential statistics were made by regression with the Ordinary Least Squares method. Exploratory analysis with word clouds, topic modeling, and natural language processing with Latent Dirichlet Allocation as a method were also made using the entire corpus from the papers. From the first register until 2023, we found eight articles in Scopus and 32 in Google Scholar; the majority of the studies and the most cited were from Spain. The studies are growing fast from 2016 to 2018, and the regression shows that growth can be maintained in the coming years. Exploratory analysis shows the most frequent words are marks, models, data, and bone. Topic modeling shows that the studies are highly concentrated on similar problems and the tools to solve them, revealing that there is much more to explore with computational tools in taphonomy and paleontology as well.
    DOI:  https://doi.org/10.1590/0001-3765202420230789
  48. Alcohol Clin Exp Res (Hoboken). 2024 Aug 08.
      Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability globally. International organizations have highlighted an urgent need for improved prevention, diagnosis, and support. However, the evidence base needed to inform this is thought to be limited. We conducted two complementary reviews to (i) describe trends in the volume and characteristics of original FASD research articles (Review 1) and (ii) compare the volume of published research on FASD to that of other neurodevelopmental disorders (Review 2). In Review 1, we systematically searched MEDLINE, Embase, CINAHL and PsycInfo for original studies with FASD terms in the title, published between 2000 and 2023. We summarised study characteristics including the article topic(s), sample population, country of origin, and publication year using quantitative content analysis and time-series plots. A total of 854 studies were eligible. Studies showed a relative focus on diagnosis and screening, compared to prevention and intervention. FASD research originated from 31 countries, however most countries (68%) had fewer than 10 articles published over the 23-year review period. In Review 2, we searched PubMed for records published between 2000 and 2023 with FASD, autism, or attention-deficit-hyperactivity disorder (ADHD) terms in the title. We compared the volume of records for these conditions using descriptive statistics and time-series plots. Of the 64,069 records retrieved, 2% were for FASD, compared to 60% for autism and 38% for ADHD. FASD remains considerably under-researched. While there has been an increase in the number of original FASD research articles published annually over time, this is much lower than expected compared to publication trends for other neurodevelopmental conditions, and the wider scientific literature. Further research is needed to understand the impact of FASD across the lifespan, to inform evidence-based policy and support, and to advance progress in strength-based, stigma-reducing approaches to FASD research and practice.
    Keywords:  bibliometric analysis; fetal alcohol spectrum disorder; neurodevelopmental disorder; review
    DOI:  https://doi.org/10.1111/acer.15415
  49. Disabil Rehabil Assist Technol. 2024 Aug 07. 1-8
      Introduction: We conducted a twenty-year bibliometric analysis of scientific literature, focusing on the trends of The International Classification of Functioning, Disability and Health (ICF) use in health research.
    Methods: We retrieved 3'467 documents published between 2002 and 2022, sourced from the Web of Science Core Collection database. We used the Bibliometrix and VoSviewer tools for descriptive analyses and data visualization.
    Results: Our findings indicate a significant increase in ICF application since 2011, with an average annual growth rate of 13.19%. Prominent contributions were observed globally, with notable outputs from the U.S., Canada, Germany, the Netherlands, and Switzerland. The Ludwig Maximilian University Munich, Swiss Paraplegic Research, and McMaster University authored a quarter of the documents (24.6%). Collaboration networks of countries and institutions revealed robust partnerships, particularly between Germany and Switzerland. "Rehabilitation" was the most frequently occurring keyword, although a thematic shift towards epidemiology, aging, and health-related quality of life was observed post-2020. While rehabilitation remained the primary thematic focus, literature post-2020 highlighted epidemiology as a growing area of interest.
    Conclusions: A steady increase in ICF-based research mirrors the rising interest in a biopsychosocial and person-centered approach to healthcare. However, the literature is primarily produced by high-resource countries, with underrepresentation from low and middle-resource countries, suggesting an area of future research to address this discrepancy.
    Keywords:  ICF; International classification of functioning; bibliometric analysis; disability and health; functioning; research trends
    DOI:  https://doi.org/10.1080/17483107.2024.2385051
  50. J Med Imaging Radiat Sci. 2024 Aug 05. pii: S1939-8654(24)00457-0. [Epub ahead of print]55(4): 101726
       INTRODUCTION: Research studies tracking gender and academic publication productivity in healthcare find gender disparities in research activity, publication, and authorship. Article authorship is one of the important metrics to track when seeking to understand gender inequality in academic career advancement. Research on gender disparities in publication productivity in the field of Medical Radiation Science (MRS) is very limited thus this study analyses and explains potential gender differences in article authorship and acceptance for publication in the Journal of Medical Imaging and Radiation Sciences (JMIRS) for a 5-year period (2017-2021).
    METHODS: Gender was inferred based on the author's first name or title (e.g., Mr, Mrs or Ms). For those who left the title blank or reported as 'Dr' or 'Prof,' a series of steps were taken to identify their gender. Where gender was impossible to ascribe, these authors were excluded. Descriptive and inferential statistics are reported for the study population. Descriptive and inferential statistics are used. Percentages of females are reported, and males constitute the other portion. Chi-square, slope analysis and z-tests were used to test hypotheses.
    RESULTS: Results show that female authorship overall and in all categories of authorship placement (i.e., first, last and corresponding) increased over the timeframe reviewed. The percentage gain in the increase was higher than that for male authorship. However, male authorship started from a higher baseline in 2017 and has also increased year on year and overall, as well as in each placement category examined. More female authors were in the MRS sub-specialism Radiation Therapy (RT) than in the other MRS sub-specialisms. Analysis of the acceptance rate of articles with female authors shows a weak downward trend, and this may be related to higher submission and acceptance rates of articles by male authors during the same period.
    CONCLUSION: Male authors are overrepresented in all categories, which raises questions about the persistence of gender disparities in JMIRS authorship and article acceptance. Positive trends in female authorship indicate progress, yet there is the persistence of the significant under-representation of women in the Medical Radiation Sciences workforce in academic publishing. Recruiting more males to address the gender imbalance in the profession should not be at the expense of females' career progression.
    Keywords:  Authorship; Diagnostic imaging; Gender equity; Leadership; Sex factors; Sexism
    DOI:  https://doi.org/10.1016/j.jmir.2024.101726
  51. JMIR Pediatr Parent. 2024 Aug 08. 7 e47848
       BACKGROUND: Industry 4.0 (I4.0) technologies have improved operations in health care facilities by optimizing processes, leading to efficient systems and tools to assist health care personnel and patients.
    OBJECTIVE: This study investigates the current implementation and impact of I4.0 technologies within maternal health care, explicitly focusing on transforming care processes, treatment methods, and automated pregnancy monitoring. Additionally, it conducts a thematic landscape mapping, offering a nuanced understanding of this emerging field. Building on this analysis, a future research agenda is proposed, highlighting critical areas for future investigations.
    METHODS: A bibliometric analysis of publications retrieved from the Scopus database was conducted to examine how the research into I4.0 technologies in maternal health care evolved from 1985 to 2022. A search strategy was used to screen the eligible publications using the abstract and full-text reading. The most productive and influential journals; authors', institutions', and countries' influence on maternal health care; and current trends and thematic evolution were computed using the Bibliometrix R package (R Core Team).
    RESULTS: A total of 1003 unique papers in English were retrieved using the search string, and 136 papers were retained after the inclusion and exclusion criteria were implemented, covering 37 years from 1985 to 2022. The annual growth rate of publications was 9.53%, with 88.9% (n=121) of the publications observed in 2016-2022. In the thematic analysis, 4 clusters were identified-artificial neural networks, data mining, machine learning, and the Internet of Things. Artificial intelligence, deep learning, risk prediction, digital health, telemedicine, wearable devices, mobile health care, and cloud computing remained the dominant research themes in 2016-2022.
    CONCLUSIONS: This bibliometric analysis reviews the state of the art in the evolution and structure of I4.0 technologies in maternal health care and how they may be used to optimize the operational processes. A conceptual framework with 4 performance factors-risk prediction, hospital care, health record management, and self-care-is suggested for process improvement. a research agenda is also proposed for governance, adoption, infrastructure, privacy, and security.
    Keywords:  Fourth Industrial Revolution; Industry 4.0; Internet of Things; IoT; antenatal care; artificial intelligence; bibliometrics; data mining; deep learning; digital health; lean operations; machine learning; maternal; maternal care; maternal health care; mobile phone; monitoring; postnatal care; pregnancy; pregnancy monitoring; thematic analysis; wearable
    DOI:  https://doi.org/10.2196/47848
  52. PLoS One. 2024 ;19(8): e0307145
       INTRODUCTION: Previous studies about the replicability of clinical research based on the published literature have suggested that highly cited articles are often contradicted or found to have inflated effects. Nevertheless, there are no recent updates of such efforts, and this situation may have changed over time.
    METHODS: We searched the Web of Science database for articles studying medical interventions with more than 2000 citations, published between 2004 and 2018 in high-impact medical journals. We then searched for replications of these studies in PubMed using the PICO (Population, Intervention, Comparator and Outcome) framework. Replication success was evaluated by the presence of a statistically significant effect in the same direction and by overlap of the replication's effect size confidence interval (CIs) with that of the original study. Evidence of effect size inflation and potential predictors of replicability were also analyzed.
    RESULTS: A total of 89 eligible studies, of which 24 had valid replications (17 meta-analyses and 7 primary studies) were found. Of these, 21 (88%) had effect sizes with overlapping CIs. Of 15 highly cited studies with a statistically significant difference in the primary outcome, 13 (87%) had a significant effect in the replication as well. When both criteria were considered together, the replicability rate in our sample was of 20 out of 24 (83%). There was no evidence of systematic inflation in these highly cited studies, with a mean effect size ratio of 1.03 [95% CI (0.88, 1.21)] between initial and subsequent effects. Due to the small number of contradicted results, our analysis had low statistical power to detect predictors of replicability.
    CONCLUSION: Although most studies did not have eligible replications, the replicability rate of highly cited clinical studies in our sample was higher than in previous estimates, with little evidence of systematic effect size inflation. This estimate is based on a very select sample of studies and may not be generalizable to clinical research in general.
    DOI:  https://doi.org/10.1371/journal.pone.0307145
  53. BMJ Lead. 2024 Aug 05. pii: leader-2024-001003. [Epub ahead of print]
       OBJECTIVE: Achieving gender equity in academic medicine is not only a matter of social justice but also necessary in promoting an innovative and productive academic community. The purpose of this study was to assess gender distribution in dual MD/PhD academic programme faculty members across North America.
    METHODS: Academic metrics were analysed to quantify the relative career success of academic faculty members in MD/PhD programmes. Measured parameters included academic and leadership ranks along with nominal research factors such as peer-reviewed research publications, H-index, citation number and years of active research.
    RESULTS: Χ² analysis revealed a statistically significant (p<0.0001, χ²=114.5) difference in the gender distribution of faculty and leadership across North American MD/PhD programmes. Men held 74.2% of full professor positions, 64% of associate professor positions, 59.4% of assistant professor positions and 62.8% of lecturer positions. Moreover, men occupied a larger share of faculty leadership roles with a statistically significant disparity across all ranks (p<0.001, χ²=20.4). A higher proportion of men held positions as department chairs (79.6%), vice chairs (69.1%) and programme leads (69.4%).
    CONCLUSION: Gender disparity was prevalent in the MD/PhD programmes throughout North America with women achieving a lower degree of professional stature than men. Ultimately, steps must be taken to support women faculty to afford them better opportunities for academic and professional advancement.
    Keywords:  clinical leadership; effectiveness; efficiency; leadership assessment; management system
    DOI:  https://doi.org/10.1136/leader-2024-001003
  54. Ann Vasc Surg. 2024 Aug 01. pii: S0890-5096(24)00483-7. [Epub ahead of print]
       BACKGROUND: Since its recognition as an independent surgical subspecialty, vascular surgery has experienced rapid growth in both surgical volume and research productivity. Trends in vascular surgery research have not been well characterized. Understanding how research in the field has evolved in comparison to interventional radiology can offer insights into evolving interests and discrepancies between the specialties.
    METHODS: Primary and secondary research publications indexed in the MEDLINE database from 1992 to 2023 were analyzed using a proprietary text mining algorithm. Eight high-impact vascular surgery journals and six interventional radiology journals were included. Articles were categorized based on treatment modalities, pathologies, and other subgroup analyses. Temporal trends were assessed using linear regression and correlation analysis. A comparative analysis was performed assessing publication trends by broad pathology groups between vascular surgery and interventional radiology journals. A further subgroup analysis was conducted comparing publication trends by endovascular treatment modality for peripheral arterial disease.
    RESULTS: 28,931 vascular surgery publications and 13,094 interventional radiology publications met inclusion criteria. Publication volume grew exponentially, with over 50% emerging in the last decade. Publications exploring endovascular interventions have increasingly exceeded those focused on exclusively open interventions in research volume since 2006. Aortic pathology, carotid disease, PAD, and venous pathology represented the vast majority vascular surgery research output, with PAD exhibiting the fastest growth. Comparative analysis revealed a number of key differences in research focus and treatment modalities between vascular surgery and interventional radiology, including a greater emphasis on venous pathology in interventional radiology journals and fewer relative publications on carotid artery pathology (p < 0.001). When comparing endovascular treatments for PAD, interventional radiology journals published more frequently on endovascular brachytherapy (8.73% vs 1.02%, p < 0.001) and less frequently on atherectomy (4.29% vs 6.50%, p = 0.035) as compared to the vascular surgery journals.
    CONCLUSION: Our findings demonstrate increasing emphasis on endovascular interventions and specific pathologies in vascular surgery research. Despite some key differences, there is notable overlap in interests between vascular surgery and interventional radiology, which may represent promising opportunities for collaboration in advancing endovascular procedures. Differences in research focus may stem from specialty perspectives and be perpetuated by differences in training.
    DOI:  https://doi.org/10.1016/j.avsg.2024.06.042
  55. J Multidiscip Healthc. 2024 ;17 3715-3726
       Objective: Reasonable surgical scheduling management is crucial to optimize the utilization rate of operating room. This study aims to understand the context, frontier and hot spots of surgical scheduling management research, in order to provide reference for surgical scheduling optimization.
    Methods: Literature on operation scheduling management collected in Web of Science core collection database was searched from the database establishment to June 21, 2023. HisCite Pro 2.1 software was used to analyze the publication time, countries, research institutions, journals, authors, keywords and highly cited papers.
    Results: A total of 1383 literatures were included, and research institutions in the United States, Canada and other countries played a leading role in this field. Among them, the combination of machine algorithm and system model optimization to improve the accuracy of surgical duration prediction is the future research focus in this field.
    Conclusion: Improving operation efficiency is one of the key issues in operating room management. Managers should find the best operation scheduling plan from a more detailed and comprehensive perspective to improve operation efficiency.
    Keywords:  manage; schedule; surgery
    DOI:  https://doi.org/10.2147/JMDH.S458410
  56. Front Oncol. 2024 ;14 1405351
      Over the last decade, significant advancements have been made in breast-conserving surgery (BCS) for breast cancer. However, there is a lack of analytical and descriptive investigations on the trajectory, essential research directions, current research scenario, pivotal investigative focuses, and forthcoming perspectives. The objective of this research is to provide a thorough update on the progress made in BCS for breast cancer over the preceding decade. Retrieved from the Web of Science database, the data span from January 1, 2013, to November 30, 2023. Utilizing a set of advanced analytical instruments, we conducted comprehensive bibliometric and visual analyses. The findings underscore the predominant influence of the USA, representing 35.77% of the overall publications and playing a pivotal role in shaping research within this field. Notable productivity was evident at various institutions, including the Memorial Sloan Kettering Cancer Center, the University of Texas MD Anderson Cancer Center, and the University of Toronto. Annals of Surgical Oncology contributed the most publications in this field. An examination of keywords indicated a change in the concentration of research attention, transitioning from molecular subtype, ultrasonography, and intraoperative aspects to SEER, male breast cancer, and adjuvant measures. By offering a comprehensive bibliometric assessment, this study enhances our understanding of BCS for breast cancer. Consequently, this benefits both experienced researchers and newcomers alike, providing prompt access to essential information and fostering the extraction of innovative concepts within this specific field.
    Keywords:  breast cancer; breast-conserving surgery; global scientific frontiers; scientometrics; visualization analysis
    DOI:  https://doi.org/10.3389/fonc.2024.1405351
  57. Cureus. 2024 Jul;16(7): e63835
      Telepathology emerges as a vital tool, offering significant promise for enhancing pathology services in Africa, a region historically challenged by healthcare access and resource limitations. This review explores the development, adoption, and impacts of telepathology in Africa through a comprehensive bibliometric analysis and literature review. A methodical search in PubMed for publications up to 2024 revealed 119 pertinent studies, out of which 47 met the inclusion criteria for a focused review on telepathology's role in African healthcare settings. This research has charted a clear trajectory of growing interest in telepathology, as evidenced by the annual increase in related publications and robust international collaboration. It underscores the expanding utility of telepathology in diagnostics, education, and research within Africa, particularly in domains like dermatopathology, neuropathology, and, notably, oncology. The integration of artificial intelligence into telepathology presents new frontiers for enhancing diagnostic accuracy and efficiency. However, the review also identifies persistent challenges such as infrastructural inadequacies, a shortage of skilled professionals, and regulatory hurdles. The study highlights the indispensable role of international partnerships in advancing telepathology in the region. This review proposes a strategic pivot toward "leapfrogging," an approach that allows Africa to skip traditional developmental hurdles by directly adopting cutting-edge technologies and practices.
    Keywords:  africa; bibliometric study; healthcare systems; pathology; telemedicine; telepathology
    DOI:  https://doi.org/10.7759/cureus.63835
  58. Clin Spine Surg. 2024 May 27.
       STUDY DESIGN: Retrospective Analysis.
    OBJECTIVE: The objective of the study was to assess the impact of academic productivity at both individual and program levels on lifetime industry earnings within US orthopedic spine fellowships.
    SUMMARY OF BACKGROUND DATA: Physician-industry transparency was codified by the Physician Payments Sunshine Act (PSSA) in 2010. No study has explored the relationship between academic productivity and industry earnings at the fellowship level.
    METHODS: Inclusion criteria encompassed physicians with complete academic and industry data from orthopedic spine fellowship programs listed on the North American Spine Society (NASS) 2022-2023 fellowship directory. Academic productivity was defined via H-index on the Scopus website, and industry productivity by total lifetime earnings on the Open Payments Database (OPD).
    RESULTS: This analysis included 75 orthopedic spine fellowship programs with 320 individual physicians. Median individual physician lifetime earnings were $86,852.71 (mean: $666,580.23 ± $1,887,734.64; minimum-maximum: $10.86-$27,164,431.49) and the median individual physician (n=320 physicians) H-index was 17.0 (mean: 21.82 ± 19.28; minimum-maximum: 0-109). Median combined physician H-index per fellowship (n=75 fellowships) was 65.0 (mean: 93.08 ± 85.67; minimum-maximum: 3-434) and median combined physician lifetime earnings was $927,771.60 (mean: $2,844,075.64 ± $4,942,089.56; minimum-maximum: $1,112.32-$29,983,900.69). A positive correlation was observed between academic productivity and industry productivity at an individual level (P<0.001; Spearman's rho = 0.467). This correlation was stronger at the fellowship level (P<0.001; Spearman's rho = 0.734). There was no significant difference in total lifetime earnings (P=0.369) or H-index per fellowship (P=0.232) when stratified by region of the fellowship program in the United States.
    CONCLUSION: Orthopedic spine surgery fellowship programs in the United States exhibit a positive correlation between academic productivity and nonresearch industry lifetime earnings at both individual and program levels. This correlation is stronger at the program level, and regional differences among fellowship programs do not significantly impact academic or industry productivity.
    DOI:  https://doi.org/10.1097/BSD.0000000000001639
  59. J Med Libr Assoc. 2024 Apr 01. 112(2): 88-94
       Objective: Wikipedia is the most frequently accessed online health information resource and is well positioned as a valuable tool for public health communication and knowledge translation. The authors aimed to explore their institution's health and medical research reach by analyzing its presence in Wikipedia articles.
    Methods: In October 2022, a comprehensive database search was constructed in PubMed to retrieve clinical evidence syntheses published by at least one author affiliated with McMaster University from 2017 to 2022, inclusive. Altmetric Explorer was queried using PubMed Identifiers and article titles to access metadata and Wikipedia citation data. 3,582 health evidence syntheses from at least one McMaster University affiliated author were analyzed.
    Results: Six percent (n=219) of health evidence syntheses from the authors' institution were cited 568 times in 524 unique Wikipedia articles across 28 different language editions. 45% of citations appeared in English Wikipedia, suggesting a broad global reach for the institutions' research outputs. When adjusted for open access publications, 8% of McMaster University's health evidence syntheses appear in Wikipedia.
    Conclusion: Altmetric Explorer is a valuable tool for exploring the reach of an institution's research outputs. Isolating Altmetric data to focus on Wikipedia citations has value for any institution wishing to gain more insight into the global, community-level reach of its contributions to the latest health and medical evidence.
    Keywords:  Citations; Wikipedia; research reach
    DOI:  https://doi.org/10.5195/jmla.2024.1730
  60. Int J Nanomedicine. 2024 ;19 7631-7671
      Psoriasis is an immune-mediated inflammatory skin disease where topical therapy is crucial. While various dosage forms have enhanced the efficacy of current treatments, their limited permeability and lack of targeted delivery to the dermis and epidermis remain challenges. We reviewed the evolution of topical therapies for psoriasis and conducted a bibliometric analysis from 1993 to 2023 using a predictive linear regression model. This included a comprehensive statistical and visual evaluation of each model's validity, literature profiles, citation patterns, and collaborations, assessing R variance and mean squared error (MSE). Furthermore, we detailed the structural features and penetration pathways of emerging drug delivery systems for topical treatment, such as lipid-based, polymer-based, metallic nanocarriers, and nanocrystals, highlighting their advantages. This systematic overview indicates that future research should focus on developing novel drug delivery systems characterized by enhanced stability, biocompatibility, and drug-carrying capacity.
    Keywords:  bibliometric; drug delivery; nanocarriers; nanoparticle; psoriasis; topical treatment
    DOI:  https://doi.org/10.2147/IJN.S461514
  61. Heliyon. 2024 Jul 30. 10(14): e34307
      The literature shows that there are dimensions related to soil legislation and policy in the European Union contexts that can be better explored through bibliometric analysis, systematic reviews and quantitative approaches. Therefore, this research aims to analyse documents on soil legislation and policies, highlighting the specific cases of Portugal and the European Union (EU). The aim is to identify suggestions to improve the Portuguese and European Union soil policy instruments and measures. To achieve these objectives, a bibliometric analysis (considering text and bibliographic data) and systematic review were carried out, as well as a survey of the available soil legislation (considering qualitative data and quantitative analysis). The results show that soil legislation and policy have become more relevant in recent years and that concerns are about soil health, protection and safety, as well as risk mitigation, biodiversity preservation and the maintenance of ecosystem services. However, some topics could be further explored in future research, namely those related to multidisciplinarity, smart methodologies, soil salinisation, innovation and quantitative approaches to assessing policy impacts. This study presents suggestions that can be considered by the Portuguese and European Union policymakers to improve the respective soil legislation and policies. Defining a regulatory system for soils in the European Union has not been easy over time, although there have been attempts, given the specificities of the contexts related to soils and the reluctance of some member states to take certain measures. The approaches and analysis topics considered are innovative (there aren't many scientific documents on the topics that address bibliometric analysis and quantitative assessments with qualitative data) and bring novelty to the literature.
    Keywords:  Bibliographic data; Qualitative data; Soil strategy; Word cloud
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e34307
  62. Front Plant Sci. 2024 ;15 1410738
       Introduction: Phenomics, an interdisciplinary field that investigates the relationships between genomics and environmental factors, has significantly advanced plant breeding by offering comprehensive insights into plant traits from molecular to physiological levels. This study examines the global evolution, geographic distribution, collaborative efforts, and primary research hubs in plant phenomics from 2000 to 2021, using data derived from patents and scientific publications.
    Methods: The study utilized data from the EspaceNet and Lens databases for patents, and Web of Science (WoS) and Scopus for scientific publications. The final datasets included 651 relevant patents and 7173 peer-reviewed articles. Data were geocoded to assign country-level geographical coordinates and underwent multiple processing and cleaning steps using Python, Excel, R, and ArcGIS. Social network analysis (SNA) was conducted to assess collaboration patterns using Pajek and UCINET.
    Results: Research activities in plant phenomics have increased significantly, with China emerging as a major player, filing nearly 70% of patents from 2010 to 2021. The U.S. and EU remain significant contributors, accounting for over half of the research output. The study identified around 50 global research hubs, mainly in the U.S. (36%), Western Europe (34%), and China (16%). Collaboration networks have become more complex and interdisciplinary, reflecting a strategic approach to solving research challenges.
    Discussion: The findings underscore the importance of global collaboration and technological advancement in plant phenomics. China's rise in patent filings highlights its growing influence, while the ongoing contributions from the U.S. and EU demonstrate their continued leadership. The development of complex collaborative networks emphasizes the scientific community's adaptive strategies to address multifaceted research issues. These insights are crucial for researchers, policymakers, and industry stakeholders aiming to innovate in agricultural practices and improve crop varieties.
    Keywords:  agricultural innovation; collaborations; geographic dynamics; networks; patents; plant phenomics; publications; social network analysis
    DOI:  https://doi.org/10.3389/fpls.2024.1410738
  63. Oxid Med Cell Longev. 2024 ;2024 2121733
      Over the past decade, there has been a notable surge in research dedicated to unraveling the intricate role of tight junction proteins in blood-brain barrier (BBB) damage associated with ischemic stroke. This bibliometric analysis explores the expansive landscape of occludin research, a key tight junction protein, during the years 2000-2023, shedding light on the global scientific contributions, collaborations, and emerging trends in this critical area of stroke pathogenesis. China and the United States emerge as significant contributors, underscoring their prominence in advancing our understanding of tight junction proteins. Occludin, identified as a linchpin in regulating BBB integrity, proves to be a pivotal player, with implications extending to the diagnosis of hemorrhagic transformation in ischemic stroke. This study identifies occludin as a potential biomarker, offering promise for early diagnosis and paving the way for novel diagnostic strategies. The analysis highlights the necessity for a more comprehensive exploration of tight junction proteins, including occludin and claudin-5, particularly in the context of acute cerebral ischemia. The unique healthcare landscape in Kazakhstan adds urgency to the call for further scientific research in this region, emphasizing the need for tailored investigations to address specific regional challenges. This comprehensive overview not only delineates the current state of occludin research but also signals the direction for future investigations. The identified knowledge gaps and emerging trends provide a roadmap for researchers and policymakers alike, with implications for both scientific discourse and clinical practice. Moving forward, a deeper understanding of tight junction proteins, informed by the insights gleaned from this study, holds the potential to shape targeted therapeutic interventions and diagnostic strategies, ultimately contributing to advancements in global stroke care.
    DOI:  https://doi.org/10.1155/2024/2121733
  64. JMA J. 2024 Jul 16. 7(3): 297-298
      
    Keywords:  Artificial Intelligence; JMA Journal; Journal Impact factor
    DOI:  https://doi.org/10.31662/jmaj.2024-0106
  65. Cancer Sci. 2024 Aug 06.
      
    Keywords:  cell line; osteosarcoma; publications; retracted publication; review
    DOI:  https://doi.org/10.1111/cas.16303
  66. Parasitol Int. 2024 Aug 04. pii: S1383-5769(24)00093-X. [Epub ahead of print]103 102942
      Trypanosoma and Leishmania species are responsible of a range of Neglected Tropical Diseases (NTDs) from disfiguring conditions to fatal processes in humans. Both genera also affect wild and domestic animals causing diseases of public health significance and high economic impact on farm economy of developing areas. Japan has been actively involved in overseas cooperation and the country has a large scientific community. However, there is no information on the scientific output of Japanese scientists and institutions on these two NTDs. To explore the Japanese contribution and its profile, we have mined Web of Science database from 1971 to 2022 the articles by Japanese scientists, scientific areas and institutions, time-related variations of these parameters, and involvement in cooperation activities with foreign scientists. Research on Trypanosoma has been present in all the studied period, with higher production, whereas Leishmania-related activities showed a delay. A steady increased of Japanese scientific output was found up to the beginning of 2000s, whereas a certain stagnation was found in the present century. Low growth rate of research output on these two NTDs by Japanese authors in the 21st century is not correlated neither to the pattern found globally nor the situation in other parasitic infections. Thus, other elements should be considered in future analysis including the actual number of scientists involved and the available funding. Reinforcement of research groups from Japanese institutions and widening the scope of collaborations, particularly with health and academic centers from endemic regions, could trigger the Japanese productivity in the research area.
    Keywords:  International cooperation; Japan; Leishmania research; Scientific production; Trypanosoma research; VOSviewer; WOS database
    DOI:  https://doi.org/10.1016/j.parint.2024.102942
  67. Angiology. 2024 Aug 09. 33197241273357
      This bibliometric analysis scrutinizes the evolution and current challenges in the use of Inferior Vena Cava (IVC) filters, focusing on trends from 2004 to 2023. Analyzing 2470 records, we report the United States' dominant role, with over half of the studies, and a significant shift towards retrievable filters. Despite technological advancements, controversies persist regarding efficacy, safety, and retrieval issues. Our findings point to the need for refined clinical guidelines and enhanced management strategies to navigate the complex landscape of IVC filter utilization effectively.
    Keywords:  complication; inferior vena cava filters; pulmonary embolism; retrievable filters
    DOI:  https://doi.org/10.1177/00033197241273357
  68. Plast Surg (Oakv). 2024 Aug;32(3): 508-514
      Background: As plastic surgery continues to evolve, an increasing number of surgeons are attaining additional degrees (ADs). Prior studies illustrate this trend of increased AD attainment among plastic surgery faculty within the United States. Yet, no such study has documented AD attainment variability and influence within Canadian plastic surgery faculty. Objectives: Our objective was to investigate the relationship between AD attainment and gender, alongside research productivity, and academic rank of Canadian plastic surgery faculty members. Methods: All Canadian academic plastic surgery faculty members were identified and information regarding gender, academic rank, research productivity, timing of AD attainment was recorded. AD was defined as any degree beyond a medical degree or equivalent. Results: A total of 299 faculty members were identified. Of these, 33% (N = 99) attained an AD. A higher percentage of females (40%) obtained ADs compared to males (30%) (P = .0402). When controlling for number of years in practice, there was a significantly larger proportion of females than males with ADs as assistant and associate professor (P = .033). Faculty with ADs were associated with higher research productivity and higher academic rank than those with MDs (P < .05). ADs were commonly obtained post-residency (38%) and most common ADs were MSc (51%) and PhDs (21%). It was found that the Canadian plastic surgeons were less likely to pursue MBAs than US plastic surgeons (P = .002). Conclusion: One-third of Canadian academic plastic surgeons had ADs. Those with ADs present with higher research productivity and academic rank. When segmented by gender, there were significant differences among AD holders. The results of this study will lend support to ongoing endeavors voicing the need for gender equity in academic plastic surgery.
    Keywords:  academic; advanced degree; degrees; faculty; plastic surgery
    DOI:  https://doi.org/10.1177/22925503221144039
  69. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2386225
      
    Keywords:  CAR-T cells; bibliometric; hematological malignancies; search strategy
    DOI:  https://doi.org/10.1080/21645515.2024.2386225
  70. Behav Brain Res. 2024 Aug 02. pii: S0166-4328(24)00334-6. [Epub ahead of print] 115178
       BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder that seriously affects the quality of the elderly's lives worldwide. The main pathological features of AD are amyloid plaques formed by β-amyloid (Aβ) and neuronal fibrillary tangls (NFTs) formed by hyperphosphorylated Tau protein. The formation process of these pathological features is closely related to inflammatory response, so anti-inflammatory treatment has become a potential treatment for AD. In recent years, more and more research has shown that the anti-inflammatory therapy can relieve the symptoms of AD and improve cognitive function, which provides a valuable research direction for the treatment of AD strategy. Therefore, a comprehensive understanding of the hotspots and development trends of AD anti-inflammatory research is important for promoting the further development of this field and improving the quality of life of patients.
    METHODS: This study used bibliometric methods, with AD and anti-inflammatory as key words, collected 7638 AD anti-inflammatory studies collected in Web of Science Core Collection (WoSCC) literature database since 2000, and conducted an in-depth analysis of the research hotspots and potential trends in this field.
    RESULTS: The depth and breadth of AD anti-inflammatory research are in the stage of rapid development, and the hot focus is on exploring the role of inflammation in the pathogenesis of AD, especially the interaction of microglia in the neuroinflammatory mechanism. Secondly, the treatment effect and potential risks of anti-inflammatory drugs such as non-steroidal anti-inflammatory drugs (NSAIDs) on AD are also the focus of research. Therefore, researchers have carried out a series of animal experiments and prospective clinical studies on anti-inflammatory drugs for the treatment of AD, forming a comprehensive research system from basic research to clinical research. As for the future development trend, we believe that the further exploration of inflammation in the pathogenesis of AD will still be one of the key directions, and the application of big data and artificial intelligence technology is expected to provide strong support for the association between inflammation and AD progression. Moreover, the development of novel anti-inflammatory drugs for the inflammatory mechanism of AD will be another major trend for future research. At the same time, personalized treatment strategies and alternative supplements of medicine will also become one of the hotspots of future research. Through the comprehensive use of anti-inflammatory drugs, nutritional supplements, lifestyle intervention and other means, more comprehensive and effective treatment plans for AD patients are expected.
    CONCLUSION: This research analyzes the overall development trend of AD anti-inflammatory research field since 2000, and provides a comprehensive perspective for the progress of AD anti-inflammatory research. Overall, the field of AD anti-inflammatory research is facing a broad development prospect. In the future, with further research and technological advances, we have resason to expect more effective and safer treatment options for AD patients to help them improve their quality of life and delay disease progression.
    Keywords:  Alzheimer’s disease; Anti-inflammatory; Bibliometric analysis; Neuroinflammation
    DOI:  https://doi.org/10.1016/j.bbr.2024.115178
  71. Cancer Control. 2024 Jan-Dec;31:31 10732748241266490
       BACKGROUND: Lung cancer is the most common cancer in the world and has become one of the malignancies with the highest incidence and mortality; more than half of patients die within one year of being diagnosed with lung cancer. In recent years, the concept of "patient-centered" service has gained popularity, and patients' subjective feelings have gradually been used in clinical decision-making. Therefore, this study determined the application of visual patient report outcomes in the field of lung cancer, in order to provide reference for specific clinical practice.
    METHODS: Using the Web of Science core collection as the main analysis content, Citespace and VOSviewer were used to conduct this scientometric study.
    RESULTS: A total of 499 literatures that met the inclusion criteria were retrieved. The most prolific institution was The University of Texas MD Anderson Cancer Center, and the United States dominates this field.
    CONCLUSION: The measurement of patient-reported outcomes is considered the gold standard for effectively evaluating patients' perceptions of clinical interventions or diseases. It is recommended that patient-reported outcomes be integrated into routine care for cancer patients in order to enhance communication between patients and healthcare providers.
    PATIENT OR PUBLIC CONTRIBUTION: Not applicable. All data in this paper are obtained from the web of science database.
    Keywords:  VOSviewer; bibliometrics visualization analysis; lung cancer; patient-reported outcomes
    DOI:  https://doi.org/10.1177/10732748241266490
  72. Gerontologist. 2024 Aug 03. pii: gnae095. [Epub ahead of print]
       BACKGROUND AND OBJECTIVES: Literature regarding successful aging reflects a wide variety of fields and perspectives. Given the range of definitions and approaches found in published literature, it is important to investigate clusters of topics studied over time. This study aimed to show the change of topic clusters within successful aging studies.
    RESEARCH DESIGN AND METHODS: The study used topic modeling methodology to analyze vast amounts of abstract data. Among publications collected from Scopus (4,458) and Web of Science (5,187), 5,610 publications were analyzed. Topic clusters were analyzed in two ways: by a) division of time (1960s - 1990s, 2000s, 2010s, 2020s) and b) all years combined.
    RESULTS: In the 1960s - 1990s, 11 topic clusters ranging from health to emotional well-being emerged without any dominant domain. In the 2000s, two clusters related to social support and health appeared as major clusters. In the 2010s, one topic cluster that included words related to health and social participation was the biggest. In the 2020s, emotional health and social participation appeared again as one of the major clusters and health-related topics started to diverge into subgroups like physical health and mental health. In all years of publications combined, the major cluster involved words that are related to either health or social domains.
    DISCUSSION AND IMPLICATIONS: Results revealed that successful aging has been studied in many fields using multidimensional perspectives. The dominant categories were health and social domains. These findings suggest interprofessional practice, an interdisciplinary approach in research, and multi-sector involvement in policy.
    Keywords:  clustering; health; older adult; social engagement; social participation
    DOI:  https://doi.org/10.1093/geront/gnae095
  73. J Hist Neurosci. 2024 Aug 09. 1-22
      In the neurosciences, concepts play an important role in the conception and direction of research. Among the theoretical notions and direction of research, plasticity stands out because of the multiple ways in which scientists use it to describe and interpret how the nervous system changes and adapts to different requirements. The occurrence of different conceptualizations of plasticity in the scientific literature during the second half of the twentieth century and up to the present was investigated using bibliometric methods. Throughout the period analyzed, synaptic plasticity has remained the dominant conceptualization of plasticity. However, scientists have continued to introduce novel plasticity concepts reflecting the scientific advances they have made in understanding the dynamic nature of the nervous system. The conceptual evolution of plasticity documents that the view of the adult nervous system as immutable has been replaced by an understanding of the nervous system as capable of lifelong change and adaptation.
    Keywords:  Anchor concept; Web of Science (WOS); bibliometric data; concept in flux; plasticity; pubmed; scientific concepts
    DOI:  https://doi.org/10.1080/0964704X.2024.2371783
  74. J Med Libr Assoc. 2024 Apr 01. 112(2): 133-139
       Background: Libraries provide access to databases with auto-cite features embedded into the services; however, the accuracy of these auto-cite buttons is not very high in humanities and social sciences databases.
    Case Presentation: This case compares two biomedical databases, Ovid MEDLINE and PubMed, to see if either is reliable enough to confidently recommend to students for use when writing papers. A total of 60 citations were assessed, 30 citations from each citation generator, based on the top 30 articles in PubMed from 2010 to 2020.
    Conclusions: Error rates were higher in Ovid MEDLINE than PubMed but neither database platform provided error-free references. The auto-cite tools were not reliable. Zero of the 60 citations examined were 100% correct. Librarians should continue to advise students not to rely solely upon citation generators in these biomedical databases.
    Keywords:  Auto-citation generator; Ovid MEDLINE; PubMed; biomedical databases; citation on demand; information literacy; librarians
    DOI:  https://doi.org/10.5195/jmla.2024.1718
  75. J Thorac Cardiovasc Surg. 2024 Aug 06. pii: S0022-5223(24)00619-6. [Epub ahead of print]
      
    DOI:  https://doi.org/10.1016/j.jtcvs.2024.07.019