bims-evares Biomed News
on Evaluation of research
Issue of 2023–12–24
eighty-two papers selected by
Thomas Krichel, Open Library Society
  1. Comprehensive Bibliometric Analysis of Research Articles on Post-Herpetic Neuralgia and Varicella-Zoster Virus: A 20-Year Review(2003-2022).
  2. Application of medical imaging in ovarian cancer: a bibliometric analysis from 2000 to 2022.
  3. Knowledge mapping of idiopathic scoliosis genes and research hotspots (2002-2022): a bibliometric analysis.
  4. Global research status analysis of the association between aortic aneurysm and inflammation: a bibliometric analysis from 1999 to 2023.
  5. Hotspots and frontiers in PSMA research for prostate cancer: a bibliometric and visualization analysis over the past 20 years.
  6. Research trends and hotspots in exercise rehabilitation for coronary heart disease: A bibliometric analysis.
  7. PRISMA-the 100 most-cited articles on chondrosarcoma recurrence: A bibliometric analysis.
  8. Research trends and hotspots of exercise for people with sarcopenic: A bibliometric analysis.
  9. Bibliometrics and visual analysis of metformin and gut microbiota from 2012 to 2022: A systematic review.
  10. Current status of research on emergency surgery score in trauma patients: a bibliometric analysis.
  11. Hotspots and frontiers of the relationship between gastric cancer and depression: A bibliometric study.
  12. Global trends and research hotspots of stroke and magnetic resonance imaging: A bibliometric analysis.
  13. Investigation of effects of Circadian Rhythm in Sport: A bibliometric analysis.
  14. Developmental defects of enamel: a bibliometric analysis of the top 100 most-cited papers.
  15. A dynamic study of the postoperative management of thyroid cancer from 2003 to 2022: a bibliometric analysis.
  16. Bibliometric insights in advances of endoscopic thyroidectomy: research status, hotspots, and global trends.
  17. Global research trends and prospects related to tumor microenvironment within Triple Negative Breast Cancer: a bibliometric analysis.
  18. Macrophages in head and neck squamous cell carcinoma: A bibliometric analysis.
  19. Research Trends of Acupuncture Therapy for Chronic Pain-Related Depression or Anxiety from 2003 to 2023: A Bibliometric Analysis.
  20. The Top 100 Most-Cited Articles on the Treatment of Lymphedema.
  21. Visualizing the global trends of peptides in wound healing through an in-depth bibliometric analysis.
  22. Global characteristics and trends in research on Candida auris.
  23. Correlation between journal metrics-based academic evaluation and researchers' ethics.
  24. Bibliometric analysis and visualization of endocrine therapy for breast cancer research in the last two decade.
  25. Top 50 Highly Cited Publications in Facelift Surgery: A 50-Year Bibliometric Analysis Review.
  26. Systematic bibliometric and visualized analysis of research hotspots and trends in artificial intelligence in autism spectrum disorder.
  27. Evolving educational landscape in pathology: a comprehensive bibliometric and visual analysis including digital teaching and learning resources.
  28. Research hotspots and trends in the relationship between genetics and major depressive disorder: A scientometric analysis from 2003 to 2023.
  29. Research Focuses and Trends in Multiple Sclerosis: A Scientometric Analysis.
  30. Mapping knowledge structure and themes trends of cancer-associated fibroblasts: a text-mining study.
  31. Circle packing charts generated by ChatGPT to identify the characteristics of articles by anesthesiology authors in 2022: Bibliometric analysis.
  32. Early predictors in language-based learning disabilities: a bibliometric analysis.
  33. Research hotspots and trends of artificial intelligence in rheumatoid arthritis: A bibliometric and visualized study.
  34. Reflection on Ramadan Fasting Research Related to Sustainable Development Goal 3 (Good Health and Well-Being): A Bibliometric Analysis.
  35. Trends in physical activity research for breast cancer - A bibliometric analysis of the past ten years.
  36. Evolution, current status, and future trends of maxillary skeletal expansion: a bibliometric analysis.
  37. [The characteristics and citation analysis of the publications in the National Medical Journal of China from 2017 to 2019].
  38. Leadership through a gender lens: Disparities in Dental Research.
  39. Visualization of the relationship between macrophage and wound healing from the perspective of bibliometric analysis.
  40. Intestinal barrier in inflammatory bowel disease: A bibliometric analysis.
  41. Big data research in nursing: A bibliometric exploration of themes and publications.
  42. [ASPECTS AFFECTING PEDIATRIC OPHTHALMOLOGY AND STRABISMUS PUBLICATION TIMES].
  43. Global trends and future directions in online learning for medical students during and after the COVID-19 pandemic: A bibliometric and visualization analysis.
  44. Bibliometric analysis of three international journals on public health dentistry: A comparative study from 2011 to 2020.
  45. Spatial and Scientometric study of the Brazilian scientific production on Antarctic soils and permafrost.
  46. Advances in Transdermal Drug Delivery Systems: A Bibliometric and Patent Analysis.
  47. Opportunities and challenges of computer aided diagnosis in new millennium: A bibliometric analysis from 2000 to 2023.
  48. A 10-year analysis of citations and impact factors in plastic surgery journals.
  49. Bibliometric and visualized analysis of diabetic macular edema.
  50. Gender and research productivity of award recipients among Canadian national ophthalmology and affiliate subspecialty societies.
  51. Stem Cell Therapy in Neonatal Hypoxic-Ischemic Encephalopathy and Cerebral Palsy: a Bibliometric Analysis and New Strategy.
  52. A bibliometric and knowledge-map study of CAR-T cell-related cytokine release syndrome (CRS) from 2012 to 2023.
  53. Trends on adsorption of lead (Pb) using water hyacinth: Bibliometric evaluation of Scopus database.
  54. Rats in Epilepsy Research: A Bibliometric Analysis of Citations Between 1969 and 2020 on Experimental Models in Epilepsy.
  55. Knowledge mapping of vocational education and training research (2004-2020): a visual analysis based on CiteSpace.
  56. Gender disparities among publications within international sexual medicine urology journals and the impact of blinding in the review process.
  57. Impact of Integrated Vascular Surgery Residency Training Pathway and Professional Development Time on Career Choice and Research Productivity.
  58. Methodological Assessment of the 100 Most Cited Articles in Total Knee Arthroplasty in the Last Decade Compared to the All-Time list.
  59. Exploring the Research Landscape of High Myopia: Trends, Contributors, and Key Areas of Focus.
  60. Authorship inequalities in global health research: the IeDEA Southern Africa collaboration.
  61. Top 25 Most-Cited Articles on Robotic-Assisted Lumbar Spine Surgery.
  62. The prevalence and risk of depression in aged COVID-19 survivors: a bibliometric and meta-analysis.
  63. Analysis of scientific and technological trends in the incorporation of activated carbon in advanced oxidation processes-a bibliometric study.
  64. Insights into the mechanisms and key factors influencing biofilm formation by Aeromonas hydrophila in the food industry: A comprehensive review and bibliometric analysis.
  65. Bibliometric analysis of water kefir and milk kefir in probiotic foods from 2013 to 2022: A critical review of recent applications and prospects.
  66. Comments on 'mapping the landscape of immunonutrition and cancer research: a comprehensive bibliometric analysis on behalf of Nutrionc Research Group'.
  67. Ten Years later: Assessments of the integrity of publications from one research group with multiple retractions.
  68. Brazilian South-South Scientific Collaboration and The Sustainable Development Goals.
  69. Benthic foraminifera as bioindicators of marine pollution: A bibliometric approach to unravel trends, patterns and perspectives.
  70. Bibliometric analysis, physical properties, and experimental evaluation of additives-diesel ternary blends.
  71. Alcohol, cardiovascular disease and industry funding: A co-authorship network analysis of epidemiological studies.
  72. Academic and Demographic Characteristics of Pediatric Orthopaedic Division Chiefs in the United States.
  73. Evaluation of the presence of double-organ bias in published randomised controlled dacryocystorhinostomy studies.
  74. World trends in publication for maxillofacial and dental trauma in the elderly.
  75. An examination of retracted articles in nursing literature.
  76. Anais Brasileiros de Dermatologia: adjustments to publication standards for authors. Expansion of Editorial Boards. Considerations about bibliometric analyses.
  77. Current Status and Trends in Lung Transplant Research Funded by the National Natural Science Foundation of China.
  78. Effects of curcumin on non-alcoholic fatty liver disease: A scientific metrogy study.
  79. Trends in Mohs surgery fellowship directors.
  80. Unlocking citation obsession and academic identity: the importance of ORCID numbers.
  81. Gender representation among speaking and leader roles at European Cardio-thoracic surgical annual meetings.
  82. Citations show gender bias - and the reasons are surprising.
  1. J Pain Res. 2023 ;16 4267-4279
    Comprehensive Bibliometric Analysis of Research Articles on Post-Herpetic Neuralgia and Varicella-Zoster Virus: A 20-Year Review(2003-2022).
    Hongli Zhang, Yong Zhao.
       Objective: Post-herpetic neuralgia (PHN) is a debilitating condition that has garnered considerable attention from pain physicians due to its association with the or Varicella-Zoster Virus (VZV). In this study, we aimed to conduct a bibliometric analysis to quantitatively assess the research outcomes related to PHN and VZV over the past two decades (2003-2022).
    Methods: We conducted a bibliometric analysis by querying the Web of Science database for articles related to PHN published from 2003 to 2022. In this analysis, we collected relevant information from the database including the number of publications, publication year, source, country, institution, and citation data.
    Results: A total of 1073 publications were extracted from the database, with 387 articles (36.1%) being authored by individuals from the United States, making it the leading country in terms of article publications. The top ten institutions that made significant contributions to research on PHN and VZV were primarily concentrated within the United States. Notably, the New England Journal of Medicine and Pain claimed the two highest positions in terms of citation count, with 2482 and 1591 citations, respectively. The topics covered in these articles mainly revolved around "Postherpetic Neuralgia", "Herpes Zoster", "Epidemiology", "Vaccine", and "Quality-of-life".
    Conclusion: Over the past two decades, there has been a gradual increase in publications on PHN and VZV, demonstrating significant advancements in academic achievements. Vaccines have proven effective in reducing PHN incidence among the elderly, but there is a lack of research on interventional treatments and underlying mechanisms. To elevate evidence-based medicine, researchers should conduct more controlled clinical trials. Additionally, leveraging pathogenesis research findings can lead to the development of better pain relief medications.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; herpes zoster virus; postherpetic neuralgia; varicella-zoster virus
    DOI:  https://doi.org/10.2147/JPR.S432485
  2. Front Oncol. 2023 ;13 1326297
    Application of medical imaging in ovarian cancer: a bibliometric analysis from 2000 to 2022.
    Yinping Leng, Shuhao Li, Jianghua Zhu, Xiwen Wang, Fengyuan Luo, Yu Wang, Lianggeng Gong.
       Background: Ovarian cancer (OC) is the most lethal tumor within the female reproductive system. Medical imaging plays a significant role in diagnosis and monitoring OC. This study aims to use bibliometric analysis to explore the current research hotspots and collaborative networks in the application of medical imaging in OC from 2000 to 2022.
    Methods: A systematica search for medical imaging in OC was conducted on the Web of Science Core Collection on August 9, 2023. All reviews and articles published from January 2000 to December 2022 were downloaded, and an analysis of countries, institutions, journals, keywords, and collaborative networks was perfomed using CiteSpace and VOSviewer.
    Results: A total of 5,958 publications were obtained, demonstrating a clear upward trend in annual publications over the study peroid. The USA led in productivity with 1,373 publications, and Harvard University emerged as the most prominent institution with 202 publications. Timmerman D was the most prolific contributor with 100 publications, and Gynecological Oncology led in the number of publications with 296. The top three keywords were "ovarian cancer" (1,256), "ultrasound" (725), and "diagnosis" (712). In addition, "pelvic masses" had the highest burst strength (25.5), followed by "magnetic resonance imaging (MRI)" (21.47). Recent emergent keywords such as "apoptosis", "nanoparticles", "features", "accuracy", and "human epididymal protein 4 (HE 4)" reflect research trends in this field and may become research hotspots in the future.
    Conclusion: This study provides a comprehensive summary of the key contributions of OC imaging to field's development over the past 23 years. Presently, primary areas of OC imaging research include MRI, targeted therapy of OC, novel biomarker (HE 4), and artificial intelligence. These areas are expected to influence future research endeavors in this field.
    Keywords:  Citespace; bibliometric analysis; collaborative network; medical imaging; ovarian cancer
    DOI:  https://doi.org/10.3389/fonc.2023.1326297
  3. Front Pediatr. 2023 ;11 1177983
    Knowledge mapping of idiopathic scoliosis genes and research hotspots (2002-2022): a bibliometric analysis.
    Like Ru, Hong Zheng, Wenjun Lian, Shuying Zhao, Qimeng Fan.
       Background: The etiology of idiopathic scoliosis (IS) remains unclear. Gene-based studies on genetic etiology and molecular mechanisms have improved our understanding of IS and guided treatment and diagnosis. Therefore, it is imperative to explicate and demarcate the preponderant areas of inquiry, key scholars, and their aggregate scholarly output, in addition to the collaborative associations amongst publications or researchers.
    Methods: Documents were retrieved from the Web of Science Core Collection (WoSCC) with the following criteria: TS = ("idiopathic scoliosis" AND gene) refined by search operators (genomic OR "hereditary substance" OR "germ plasm" OR Cistrons OR genetics OR genetic OR genes OR Polygenic OR genotype OR genome OR allele OR polygenes OR Polygene) AND DOCUMENT TYPES (ARTICLE OR REVIEW), and the timespan of 2002-01-01 to 2022-11-26. The online bibliometric analysis platform (bibliometric), bibliographic item co-occurrence matrix builder (BICOMB), CiteSpace 6.1. R6 and VOS viewer were used to evaluate articles for publications, nations, institutions, journals, references, knowledge bases, keywords, and research hotspots.
    Results: A total of 479 documents were retrieved from WoSCC. Fourty-four countries published relevant articles. The country with the most significant number of articles was China, and the institution with the most significant number of articles was Nanjing University. Citation analysis formed eight meaningful clusters and 16 high-frequency keywords. (2) The citation knowledge map included single nucleotide polymorphisms, whole exome sequencing, axonal dynamin, drug development, mesenchymal stem cells, dietary intake, curve progression, zebrafish development model, extracellular matrix, and rare variants were the current research hotspots and frontiers.
    Conclusions: Recent research has focused on IS-related genes, whereas the extracellular matrix and unusual variants are research frontiers and hotspots. Functional analysis of susceptibility genes will prove to be valuable for identifying this disease.
    Keywords:  Citespace; VOSviewer; bibliometrics; data visualization; genes; idiopathic scoliosis
    DOI:  https://doi.org/10.3389/fped.2023.1177983
  4. Front Cardiovasc Med. 2023 ;10 1260935
    Global research status analysis of the association between aortic aneurysm and inflammation: a bibliometric analysis from 1999 to 2023.
    Qiuguo Wang, Guihuan Chen, Zhen Qi, Yifan Zeng, Ling Tan, Hao Tang.
       Background: Aortic aneurysm is a chronic arterial disease that can lead to aortic rupture, causing severe complications and life-threatening risks for patients, and it is one of the common causes of death among the elderly. Increasing evidence suggests that inflammation plays an important role in the progression of aortic aneurysm. However, there is a lack of literature-based quantitative analysis in this field.
    Methods: Up to March 30, 2023, we collected 3,993 articles related to aortic aneurysm and inflammation from the Web of Science Core Collection (WoSCC) database for bibliometric analysis. The collected literature data were subjected to visual analysis of regional distribution, institutions, authors, keywords, and other information using tools such as CiteSpace, VOSviewer, the R package "bibliometric," and online platforms.
    Results: The number of publications in this research field has been steadily increasing each year, with the United States and China being the main contributing countries. Harvard University in the United States emerged as the most active and influential research institution in this field. Jonathan Golledge and Peter Libby were identified as the authors with the highest publication output and academic impact, respectively. Researchers in this field tend to publish their findings in influential journals such as the Journal of Vascular Surgery and Arteriosclerosis Thrombosis and Vascular Biology. "Abdominal aortic aneurysm," "giant cell arteritis," "arterial stiffness," and "smooth muscle cells" were identified as the hottest topics in the field of aortic aneurysm and inflammation. In terms of keyword co-occurrence analysis, "Clinical relevant studies of AA" (red), "Inflammatory activation" (green), "Inflammatory mechanisms related to pathogenesis" (dark blue), "Cytokines" (yellow), "Risk factors" (purple), and "Pathological changes in vascular wall" (cyan) formed the major research framework in this field. "Inflammation-related pathogenesis" and "inflammation activation" have emerged as recent hot research directions, with "monocytes," "progression," and "proliferation" being the prominent topics.
    Conclusion: This study provides a comprehensive analysis of the knowledge network framework and research hotspots in the field of aortic aneurysm and inflammation through a literature-based quantitative approach. It offers valuable insights to guide scholars in identifying meaningful research directions in this field.
    Keywords:  CiteSpace; VOSviewer; aortic aneurysm; bibliometric analysis; frontier research hotspots; inflammation
    DOI:  https://doi.org/10.3389/fcvm.2023.1260935
  5. Eur J Med Res. 2023 Dec 19. 28(1): 610
    Hotspots and frontiers in PSMA research for prostate cancer: a bibliometric and visualization analysis over the past 20 years.
    Hanfei Zhang, Liu Xiao, Hangyu Xie, Lin Li.
       BACKGROUND: Prostate-specific membrane antigen (PSMA)-targeted imaging and therapy have significantly changed the management of patients with prostate cancer (PCa) at different disease stages. This advancement has attracted the attention of scholars, leading to a prolific output of scholarly publications. This study comprehensively outlines the knowledge framework associated with PSMA-based diagnosis and treatment of PCa through the application of bibliometric analysis, and discusses the potential research trends and foci.
    METHODS: Articles and reviews related to PSMA for prostate cancer from 2003 to 2022 were retrieved from Web of Science Core Collection. VOSviewer, Citespace, and R-bibliometrix were primarily employed to execute and visually represent co-authorship, co-citation, and co-occurrence analysis of countries, institutions, authors, references and keywords in this field.
    RESULTS: A total of 3830 papers were included. The papers on the field of PSMA-based PCa therapy and imaging had been continuously increased since 2003, but the rate has slowed from 2020. The United States made the largest contribution in this field, in terms of publications 997 (26.03%), H-index (110) and total citations (53,167 times). We identified the most productive institution were Technical University of Munich, and Australian institutions had become very active in recent years. Journal of Nuclear Medicine was the most prominent journal in this field. Professors Matthias Eiber and Martin G Pomper made great achievements, while Ali Afshar-Oromieh was the most co-cited author. According to the result of keywords and topics analysis, "ga-68 labeled psma ligand", "radiation dosimetry" and "HBED-CC" were major research areas in the near future, while "Extended pelvic lymph node dissection" was considered to be the future research foci.
    CONCLUSIONS: The field of psma-based PCa therapy and imaging is in the stage of vigorous development and has a bright prospect. The United States and Germany have achieved outstanding results in this area, while Australia has recently developed rapidly. It is foreseeable that more research foci will be lied in the early detection of pelvic lymph nodes and the multimodal imaging-guided surgery.
    Keywords:  Bibliometric analysis; Citespace; Prostate cancer; Prostate specific membrane antigen; VOSviewer
    DOI:  https://doi.org/10.1186/s40001-023-01590-w
  6. Medicine (Baltimore). 2023 Dec 15. 102(50): e36511
    Research trends and hotspots in exercise rehabilitation for coronary heart disease: A bibliometric analysis.
    Qing Wen, Qun-Hua Ma, Lin-Zhang Li, Xue-Wu Song, Hu-Kui Han, Gui-Yu Huang, Xiao-Li Tang.
      Exercise rehabilitation can improve the prognosis of patients with coronary heart disease. However, a bibliometric analysis of the global exercise rehabilitation for coronary heart disease (CHD) research topic is lacking. This study investigated the development trends and research hotspots in the field of coronary heart disease and exercise rehabilitation. CiteSpace software was used to analyze the literature on exercise therapy for CHD in the Web of Science Core Collection database. We analyzed the data of countries/institutions, journals, authors, keywords, and cited references. A total of 3485 peer-reviewed papers were found, and the number of publications on the topic has steadily increased. The most productive country is the USA (1125), followed by China (477) and England (399). The top 3 active academic institutions are Research Libraries UK (RLUK) (236), Harvard University (152), and the University of California System (118). The most commonly cited journals are Circulation (2596), The most commonly cited references are "Exercise-based cardiac rehabilitation for coronary heart disease" (75), Lavie CJ had published the most papers (48). World Health Organization was the most influential author (334 citations). The research frontier trends in this field are body composition, participation, and function. Research on the effects of physical activity or exercise on patients with CHD is a focus of continuous exploration in this field. This study provides a new scientific perspective for exercise rehabilitation and CHD research and gives researchers valuable information for detecting the current research status, hotspots, and emerging trends for further research.
    DOI:  https://doi.org/10.1097/MD.0000000000036511
  7. Medicine (Baltimore). 2023 Dec 15. 102(50): e36525
    PRISMA-the 100 most-cited articles on chondrosarcoma recurrence: A bibliometric analysis.
    Baoquan Xin, Guangjian Bai, Pan Gao, Xing Huang, Tielong Liu.
       BACKGROUND: Chondrosarcoma (CHS) is highly prone to recurrence and has become the most common malignant bone tumor in adults. The authors aim to identify and analyze the top 100 most-cited articles in this field, enabling researchers to quickly grasp the research focus and progress in the area of chondrosarcoma recurrence.
    METHODS: A search in the Web of Science database yielded a total of 305 articles related to CHS recurrence between 2013 and 2022. Filtering was done based on the titles and abstracts of the articles in the list, and the top 100 most-cited articles were selected. The following information were analyzed using bibliometric methods: article title, first author, year of publication, journal of publication, total citations, country, institution, and keywords.
    RESULTS: Among the selected 100 articles, the most frequently cited one has 224 citations. The most commonly appearing journals, institutions, and countries are as follows: "Clinical Orthopaedics Related Research" (5 times); Fudan University, University of Texas System, and Royal Orthopaedic Hospital (4 times each), with China and the USA cited the most (21 times each). The year 2018 is the most productive year (17 articles). About 97 first authors contributed one article each, and 3 had 2 articles each. Among all 229 keywords, the top 3 in frequency are CHS (20%), recurrence (4%), and surgery (3%). Twenty article topics are related to surgical treatment.
    CONCLUSION: Research on CHS recurrence is citation-rich but focuses more on treatments than understanding mechanisms, indicating a need for deeper mechanistic exploration for treatment breakthroughs in the future.
    DOI:  https://doi.org/10.1097/MD.0000000000036525
  8. Medicine (Baltimore). 2023 Dec 15. 102(50): e35148
    Research trends and hotspots of exercise for people with sarcopenic: A bibliometric analysis.
    Wanli Zang, Haohao Chen, Jin Yan, Dong Li, Ningkun Xiao, Xiaoqin Zheng, Zezhong Zhang.
      This study aimed to analyze the trends and themes in exercise and sarcopenia research using a bibliometric approach. The Web of Science citation database was used to identify papers published on exercise and sarcopenia. The retrieved data on institutions, journals, countries, authors, journal distribution, and keywords were analyzed scientometric ally using CiteSpace and VOSviewer. 2895 papers were included according to our specified inclusion criteria eventually. The data showed an upward trend in the number of published articles on exercise and sarcopenia. The countries with the highest number of publications were the United States, Japan, and England; research institutions were mainly composed of universities in Europe and the United States, and high-producing authors formed major collaborative teams, but cross-geographical and cross-institutional collaboration was not apparent; research was closely focused on 3 aspects: resistance exercise, resistance combined with other forms of exercise, and exercise combined with nutritional supplementation, of which resistance exercise was a particular focus; and recently, the research hotspots were mainly the effects of exercise on grip strength. The most cited articles were consensus guidelines published by the working group on sarcopenia in the elderly from different continents. The prevention and rehabilitation of sarcopenia in the elderly are gaining attention. Current primary exercise therapies for sarcopenia and exercise combined with nutritional supplementation have significant advantages and the potential to delay muscle decay. This suggests a promising area for future research that could benefit from further advances.
    DOI:  https://doi.org/10.1097/MD.0000000000035148
  9. Medicine (Baltimore). 2023 Dec 15. 102(50): e36478
    Bibliometrics and visual analysis of metformin and gut microbiota from 2012 to 2022: A systematic review.
    Yang Shu, Weidong Li, Qiongying Hu, Daqian Xiong.
       BACKGROUND: Metformin is an old drug used for the treatment of type 2 diabetes mellitus and can play a variety of roles by regulating the gut microbiota. The number of research articles on metformin in the gut microbiota has increased annually; however, no bibliometric tools have been used to analyze the research status and hot trends in this field. This study presents a bibliometric analysis of publications on metformin and gut microbiota.
    METHODS: We searched the Web of Science core collection database on June 8, 2023, for papers related to metformin and gut microbiota from 2012 to 2022. We used Microsoft Excel 2021, VOSviewer1.6.19, CiteSpace 6.2.4, and R software package "bibliometrix" 4.0.0 to analyze the countries, institutions, authors, journals, citations, and keywords of the included publications.
    RESULTS: We included 517 papers, and the trend in publications increased over the last 11 years. The 517 articles were from 57 countries, including 991 institutions and 3316 authors, and were published in 259 journals. China led all countries (233 papers) and the most influential institution was the Chinese Academy of Sciences (16 papers). PLOS ONE (19 papers) was the most popular journal, and Nature (1598 citations) was the most cited journal. Li and Kim were the 2 most published authors (six papers each), and Cani (272 co-citations) was the most co-cited author. "Metabolites," "aging," and "intestinal barrier" were emerging topics in this field.
    CONCLUSIONS: This bibliometric study comprehensively summarizes the research trends and progress of metformin and gut microbiota, and provides new research topics and trends for studying the effects of metformin on gut microbiota in different diseases.
    DOI:  https://doi.org/10.1097/MD.0000000000036478
  10. Transl Pediatr. 2023 Nov 28. 12(11): 2044-2052
    Current status of research on emergency surgery score in trauma patients: a bibliometric analysis.
    Zhiyong He, Zhenggang Chen, Qi Zuo, Guobing Peng, Weibing Tang, Enrico Giordan, Suresh Agarwal.
       Background: The use of a relevant emergency score can provide an accurate assessment of the patient's condition and prognosis. However, the status of related studies remains unclear. The current study analyzed the research status of emergency surgery score (ESS) of trauma patients by using bibliometric methods.
    Methods: The Science Citation Index Expanded (SCI-E) database in the Web of Science Core Collection (WOSCC) was searched using keywords "trauma" and "emergency surgery score". All records from the search results and cited references were exported to Excel, duplicate literature records were removed, information for the same author and organization in different signature forms were merged. The resulting literatures were analyzed by year of publication, citation, discipline, countries and research institutions, journals, authors, and use of keywords. The cooperation among countries, institutions, and authors was also examined.
    Results: A total of 2,175 document were retrieved. The number of published literature and the number of citations per year increased annually. The number of published documents (n=1,029) and research cooperation (centrality score, 0.44) in the United States were significantly ahead of those in other countries. The ten research institutions with the largest number of published documents were all from the United States, with much cooperation between research institutions and authors. There were many publications from China (n=108), but with few cooperations (centrality score, 0.22). The journals with the largest number of published articles were professional in the fields of trauma, emergency, and critical care. Keyword analysis showed that infection and shock were important issues besides surgery in the research related to ESS of trauma patients.
    Conclusions: Research related to ESS of trauma patients has been mainly conducted in the United States, and Chinese researchers should increase their level of cooperation.
    Keywords:  Trauma; bibliometrics analysis; emergency surgery score (ESS)
    DOI:  https://doi.org/10.21037/tp-23-443
  11. World J Gastroenterol. 2023 Dec 14. 29(46): 6076-6088
    Hotspots and frontiers of the relationship between gastric cancer and depression: A bibliometric study.
    Jia-Yu Liu, Ji-Qi Zheng, Cheng-Liang Yin, Wen-Pei Tang, Jian-Ning Zhang.
       BACKGROUND: A significant relationship between gastric cancer (GC) and depression has been found in the last 20 years. However, there is no comprehensive information that helps researchers find popular and potential research directions on GC and depression.
    AIM: To determine the research status and hotspots by bibliometric analysis of relevant publications on the relationship between GC and depression.
    METHODS: We used the Web of Science Core Collection to search and collate the literature on GC and depression from 2000 to 2022 on 31 May, 2023. Then, visualization analysis was performed using VOSviewer software (version 1.6.19) and the Bibliometrix package in R software.
    RESULTS: We retrieved 153 pertinent publications from 2000 to 2022. The annual publication count showed an overall upward trend. China had the most prominent publications and significant contributions to this field (n = 64, 41.83%). Before 2020, most studies focused on "the effect of GC on the development and progression of depression in patients." The latest research trends indicate that "the effect of depression on the occurrence and development of GC and its mechanism" will receive more attention in the future.
    CONCLUSION: The study of "the effect of depression on the occurrence and development of GC and its mechanism" has emerged as a novel research theme over the past two years, which may become a research hotspot in this field. This study provides new insights into the hotpots and frontiers of the relationship between GC and depression, potentially guiding researchers toward hot research topics in the future.
    Keywords:  Bibliometric analysis; Depression; Gastric cancer; Visualization; Web of Science
    DOI:  https://doi.org/10.3748/wjg.v29.i46.6076
  12. Medicine (Baltimore). 2023 Dec 22. 102(51): e36545
    Global trends and research hotspots of stroke and magnetic resonance imaging: A bibliometric analysis.
    Yuting Zhang, Mengtong Chen, Chunlong Liu, Bingjie He, Hongbin Dang, Jiamin Li, Hanwei Chen, Zhenzhong Liang.
       BACKGROUND: In this study, we used CiteSpace and VOSviewer to create a bibliometric visualization of research papers relating to stroke and magnetic resonance imaging (MRI) between 2000 and 2022. To fully understand the trends and hotspots in MRI and stroke research and provide new perspectives for future studies.
    METHODS: The Web of Science Core Collection was selected as the source of data for this paper. Using CiteSpace and VOSviewer, publications were analyzed for authors, countries, institutions, journals, references, and keywords.
    RESULTS: We found 1423 papers after searching and removing duplicates, which indicated an upward trend over the previous 23 years. Fiebach J.B. is the most published author (21 publications), Hacke W. is the most cited author (213 citations), and the United States (449 publications) and Harvard University (86 publications) are the most prolific nations and institutions. Stroke is the journal with the most co-citations (1275) and the most papers (171) published. The most representative reference was the 1995 article by Marler et al, which received 115 citations and had the top 3 co-occurring keywords: stroke, magnetic resonance imaging, and MRI. The article by Nogueria et al showed the strongest citation burst at the end of 2022 (strength = 17.32). High-frequency keywords in recent years are time, association, functional connectivity, thrombectomy, and rehabilitation.
    CONCLUSION: This study provides a scientific perspective on stroke and MRI research, provides valuable information for researchers to understand the current status of research, hotspots, and trends, and guides future research directions.
    DOI:  https://doi.org/10.1097/MD.0000000000036545
  13. Medicine (Baltimore). 2023 Dec 22. 102(51): e34229
    Investigation of effects of Circadian Rhythm in Sport: A bibliometric analysis.
    Jie Wang, Lina Xia.
       PURPOSE: This study conducted a bibliometric analysis of the literature on circadian rhythms and sports to identify research trends, knowledge gaps, and future directions.
    METHODS: A total of 301 manuscripts, including 245 articles and 56 reviews, were extracted from the Web of Science Core Collection (WoSCC) database, and the bibliometric analysis was performed using VOSviewer 1.6.16.
    RESULTS: The analysis revealed a continuous increase in the volume of literature on circadian rhythms and sports over the past 38 years, with a focus on the effects of circadian rhythms on physical performance, sleep quality, and jet lag. The study identified 1107 authors who have contributed to this field, with the highest number of publications from Reilly T, Chtourou H, and Atkinson G. The publications were from 512 institutions in 59 countries/regions, with Liverpool John Moores University, University of Sfax, and Manouba University being the leading institutions. The USA, UK, and Australia had the largest number of publications. The top 3 journals were Chronobiology International, Biological Rhythm Research, and Sports Medicine.
    CONCLUSION: Despite the increase in research, there are still several underexplored areas, such as the effects of circadian rhythms on cognitive and emotional processes in sports, the role of individual differences in circadian rhythms on sports outcomes, and the potential applications of circadian interventions for sports performance optimization. Future research should address these gaps to advance our understanding of the complex relationship between circadian rhythms and sports.
    DOI:  https://doi.org/10.1097/MD.0000000000034229
  14. Caries Res. 2023 Dec 15.
    Developmental defects of enamel: a bibliometric analysis of the top 100 most-cited papers.
    Gabriele Andrade-Maia, Túlio Silva Pereira, Luna Chagas Clementino, Fernanda Vieira Belém, Juan Diego Torres-Ribeiro, Matheus de França Perazzo, Paulo Antônio Martins-Junior, Marco Aurelio Benini Paschoal.
       BACKGROUND: Developmental Defects of Enamel (DDE) are a result of disturbances during formation and maturation of the enamel. Evaluating the most-cited DDE papers can provide important tools that point to the gaps and strengths of this important topic.
    SUMMARY: This bibliometric study analyzed the 100 most-cited papers on DDE. Using a combined keyword search strategy, the 100 most-cited papers in the Web of Science Core Collection (WoS-CC) were selected. Papers that addressed any type of DDE were included. The extracted data were title, number of citations, study theme, authorship, journal, type of DDE, type of dentition (primary or permanent), type of diagnosis, study design, year and country of publication. The bibliometric networks were generated through VOSviewer software. The 100 papers had a range from 78 to 459 citations. The main themes of studies were etiopathogenesis (53%), prevalence and incidence (22%) and diagnosis (8%). The author with the highest number of citations were Goodman AH and Rose JC (459 citations). Most articles were published in dental journals (47%). The most studied types of DDE were fluorosis and amelogenesis imperfecta in the permanent dentition (47%). Observational (24%) and non-systematic reviews (24%) were the most common study designs and ranged from 1977 to 2019. The country with the highest number of citations was the USA (40%).
    KEY MESSAGES: Most of the top 100 DDE papers were about fluorosis and amelogenesis imperfecta, with top papers from three continents with English as the native language. This topic is of great importance in dentistry, and the need for further studies is highlighted, especially regarding the diagnosis and treatment of some DDEs.
    DOI:  https://doi.org/10.1159/000535856
  15. Gland Surg. 2023 Nov 24. 12(11): 1579-1593
    A dynamic study of the postoperative management of thyroid cancer from 2003 to 2022: a bibliometric analysis.
    Xi Yang, Yiming Wang, Yunpeng Luo, Teng Guo, Guangde Zhang.
       Background: Over the past 20 years, the global incidence of thyroid cancer has continued to increase. The volume of literature on the postoperative management of thyroid cancer comprises 1,040 articles, from 64 countries, with 1,400 journals publishing the relevant literature, and several guidelines on the treatment of thyroid cancer. This study used bibliometric methods to identify research hotspots and explore future directions in this field.
    Methods: We comprehensively searched the Science Citation Index Expanded (SCI-E) database of the Web of Science Core Collection (WOSCC) for articles published from 2003 to 2022 on the postoperative management of thyroid cancer. Using CiteSpace 6.1.R6 and Microsoft Office Excel 2010, we evaluated and visualized the search results. Using R Studio, we generated a network of spatial geographic distribution maps and cooperative network.
    Results: A total of 1,040 publications were included in the study. The results revealed an overall upward trend in the number of publications and citations over the past 20 years. The United States of America (USA) had the largest number of publications and the highest centrality (n=282, centrality =0.28). Johns Hopkins University had highest centrality (centrality =0.15) and was the academic center of the field. Thyroid was the journal with the highest number of citations (n=826), and the American Journal of Surgical Pathology was the journal with the highest centrality (centrality =0.08). The top 10 citations in the literature were mainly guidelines and consensus statements on the management of thyroid cancer. A keyword-based clustering analysis revealed the prominence of clusters of keywords, such as follow-up, recurrent laryngeal nerve, and medullary thyroid carcinoma (MTC). A keyword burst detection analysis showed that the term papillary had the highest burst intensity (strength =8.02), while management guidelines, association guidelines, active surveillance (AS), microcarcinoma, and differentiated thyroid cancer were the current burst words.
    Conclusions: Over the past two decades, the number of relevant publications in the postoperative management of thyroid cancer field has continued to grow. Among the many research directions, follow-up, recurrent laryngeal nerve, and MTC are research hotspots. Future research is likely to revolve around guidelines and consensus statements on the management of thyroid cancer, AS, and microcarcinoma in differentiated thyroid cancer.
    Keywords:  Postoperative management; bibliometric analysis; thyroid cancer
    DOI:  https://doi.org/10.21037/gs-23-218
  16. Gland Surg. 2023 Nov 24. 12(11): 1554-1566
    Bibliometric insights in advances of endoscopic thyroidectomy: research status, hotspots, and global trends.
    Yanhao Ran, Xun Zheng, Pengyu Li, Yujie Zhang, Tianfeng Xu, Tao Wei.
       Background: Endoscopic thyroidectomy (ET) has witnessed significant advancements over the last three decades. Various surgical methods and approaches have been developed that minimize trauma, enhance aesthetics, and reduce psychological stress caused by scars. Papillary thyroid carcinoma is the main reason for thyroidectomy and ET represents an innovative technique for treating thyroid cancer. In this study, nearly three decades of scientific articles were analyzed and summarized to gain a better understanding by using bibliometric method.
    Methods: A total of 486 publications between 1996 and 2023 were retrieved from the Web of Science database through systematic searches. The objective of this study involved characterizing general information and investigating developmental trends and research frontiers. CiteSpace was employed to evaluate and visualize the results.
    Results: The query resulted 486 publications with a total citation frequency of 10,202. The top five countries in terms of the number of published articles were China, South Korea, the USA, Italy, and Japan. The top five countries in terms of literature centrality were Scotland, Israel, Brazil, the USA, and France. There were eight institutions with more than ten publications. The top ten institutions had a centrality score of 0.02 or above, indicating intensive research in this area and substantial collaboration among institutions. The most cited authors primarily originated from South Korea. Journals such as Surgical Endoscopy and Other Interventional Techniques, Surgical Laparoscopy Endoscopy & Percutaneous Techniques, Head and Neck Journal for the Sciences and Specialties of the Head and Neck, and Thyroid exerted considerable influence in this field. Keyword analysis results revealed that research predominantly focused on thyroid cancer and surgical approaches.
    Conclusions: This bibliometric study provides a comprehensive analysis of global productivity, collaboration, and research focus in the field of ET. The findings of this study serve as valuable guidance for future research in ET.
    Keywords:  Thyroid; bibliometrics; endoscopic thyroidectomy (ET); surgery; thyroid cancer
    DOI:  https://doi.org/10.21037/gs-23-198
  17. Front Immunol. 2023 ;14 1261290
    Global research trends and prospects related to tumor microenvironment within Triple Negative Breast Cancer: a bibliometric analysis.
    Peiting Li, Jun Li, Xiaofei Tong, Zhenyang Xiao, Wuliang Diao, Chi Zhong, Jianda Zhou, Wei Wu.
       Background and aims: The tumor microenvironment (TME) has pivotal parts within multiple tumor models of onset/progression, such as triple-negative breast cancer (TNBC). This bibliometric analysis was developed to explore trends and research niches revolving around TME in TNBC.
    Methods: Web of Science Core Collection was queried for identifying studies linked with TME in TNBC, after which the VOSviewer, CiteSpace, and R software programs were used to conduct bibliometric analyses and to generate corresponding visualizations.
    Results: In total, this study included 1,604 studies published from 2005-2023. The USA and China exhibited the highest numbers of citations, and the research institutions with the greatest output in this field included Harvard University, the University of Texas System, and Fudan University. Ying Wang from Sun Yat-Sen University was the most published and most cited author in this space. The highest number of articles were published in Cancer, while the greatest co-citation number was evident in Breast Cancer Research. Important keywords related to this research topic included metastasis, tumor-infiltrating lymphocytes, immunotherapy, chemotherapy, and nanoparticles. In particular, pembrolizumab, immunotherapy, nanoparticles, combination treatment, and biomarkers were topics of marked interest in recent reports.
    Conclusion: The TME in TNBC is an area of rapidly growing and evolving research interest, with extensive global collaboration helping to drive this field forward. Antitumor therapies targeting the TME in TNBC patients represent an emerging topic of future research, providing opportunities for translational findings. The results of this analysis may provide additional guidance for work focused on the TME in TNBC.
    Keywords:  CiteSpace; Triple Negative Breast Cancer; VOSviewer; WoSCC; bibliometric analysis; tumor microenvironment
    DOI:  https://doi.org/10.3389/fimmu.2023.1261290
  18. Medicine (Baltimore). 2023 Dec 15. 102(50): e36649
    Macrophages in head and neck squamous cell carcinoma: A bibliometric analysis.
    Sai Liang, Ji Wang, Zhaolei Ma, Ming Yu, Zheng-Peng Gong.
       INTRODUCTION: The tumor microenvironment in head and neck squamous cell carcinoma (HNSCC) is densely infiltrated by macrophages. Utilizing bibliometric analysis, the characteristics, hotspots for research, and research frontiers related to macrophages in HNSCC were reviewed.
    METHODS: The Web of Science Core Collection database was queried for relevant articles published from 2000 to 2022. VOSviewer and CiteSpace software were utilized to evaluate and visualize macrophage-related HNSCC research trends and hotspots.
    RESULTS: Assessment of original articles revealed that the annual number of publications regarding the role of macrophages in HNSCC has increased steadily over the past 23 years. China produced the most articles, whereas the United States had the highest number of citations and highest H-index. Wuhan University and Oral Oncology were the most productive affiliation and journal, respectively. The paper published by Bray et al in the CA-A Cancer Journal for Clinicians in 2018 had the greatest number of citations. The keywords "expression," "cancer," and "tumor-associated macrophages (TAMs)" occurred most frequently.
    CONCLUSIONS: This bibliometric investigation discovered that publications about macrophages in HNSCC are steadily increasing. The majority of studies focused on macrophage polarization, macrophage markers, and inflammation in the tumor microenvironment. Furthermore, our bibliometric analysis revealed that the immunosuppressive role of tumor-associated macrophages in the tumor microenvironment and resistance to therapy in HNSCC have recently received attention.
    DOI:  https://doi.org/10.1097/MD.0000000000036649
  19. J Pain Res. 2023 ;16 4301-4315
    Research Trends of Acupuncture Therapy for Chronic Pain-Related Depression or Anxiety from 2003 to 2023: A Bibliometric Analysis.
    Pu Yang, Tian Wang, Yu-Jun He, Sheng-Yong Su.
       Background: Chronic pain (CP) as a long-lasting stressor can often cause mood disorders, such as depression or anxiety. The comorbidity of CP and mood disorders poses challenges for treatment and increases healthcare costs. Acupuncture has emerged as a widely utilized approach to alleviate both CP and mood disorders. However, there is a lack of well-established bibliometric analyses in this area of research. Therefore, this study aimed to identify the current hotspots and research trends regarding the use of acupuncture for treating CP-related depression or anxiety.
    Methods: We searched the Web of Science Core Collection spanning from 2003 to 2023 to identify relevant literature about the use of acupuncture for treating CP-related depression or anxiety. Bibliometric and visualization analyses were performed using CiteSpace 5.7.R5 and Vosviewer 1.6.19 software.
    Results: A total of 254 articles published between 2003 and 2023 were included, revealing an upward trajectory with some fluctuations in publication numbers over the past two decades. China and the Beijing University of Chinese Medicine were the most productive country and institution in this field. Fang JQ and Vickers AJ ascended as the most prolific and influential authors, respectively. Trials was the journal with the highest number of publications, while Pain and BMJ-British Medical Journal exhibited the highest citation and centrality, respectively. "Acupuncture", "depression", and "chronic pain" were the top three keywords. The hotspots in this domain encompass types of chronic pain that predispose to negative mood, including fibromyalgia, irritable bowel syndrome (IBS), and neuropathic pain. Randomized controlled trials (RCTs), mechanisms, and evidence-based evaluations are the main research directions.
    Conclusion: This study uses bibliometric techniques to analyze the research hotspots and forefronts of acupuncture as a therapeutic approach for CP-related depression or anxiety. Our objective is to provide researchers with valuable references and identify research focal points for future investigations.
    Keywords:  VOSviewer; acupuncture; anxiety; bibliometric analysis; chronic pain; citespace; depression
    DOI:  https://doi.org/10.2147/JPR.S436434
  20. Cureus. 2023 Dec;15(12): e50887
    The Top 100 Most-Cited Articles on the Treatment of Lymphedema.
    Abdullah M Alahwal, Hattan Aljaaly.
      A multitude of articles have been published on lymphedema management. We aim to identify the 100 most-cited articles on the management of lymphedema and perform a bibliometric analysis. In July 2023, a title-specific search was made on the Scopus database using "lymphedema" as the primary search term. The top 100 most-cited articles were reviewed. The top 100 most-cited articles on lymphedema received a mean citation of 81.7 ± 71.9 per article (range of 11.0 to 420.0). The publication dates ranged from 1977 to 2015. Most of the articles were original (63.0%), interventional studies (35.0%), randomized controlled trials (RCTs) (31.0%), and systematic reviews (32.0%). The largest number of articles (31) were found between 2007 and 2011. The top 10 articles' citation counts ranged from 164 to 420 (mean of 244.7 ± 83.9 citations). Five of these 10 articles were published between the years 1990 and 2000. Twenty-five countries contributed to the 100 most-cited articles. The United States produced the most number of articles (n = 32), followed by Italy (n = 11), Sweden, and Turkey, with seven articles each. Four of the top 10 articles were RCTs; the remaining six were systematic, retrospective, and prospective studies. The New England Journal of Medicine published two of these top 10 articles. Retrospective studies had the highest mean citation with 196.5, followed by RCTs with 100.9. We identified the 100 most-cited articles that depict the advancement in treatment methods for lymphedema. This extensive information directory can be an excellent source for further research.
    Keywords:  articles; citation; lymphedema; publications; research
    DOI:  https://doi.org/10.7759/cureus.50887
  21. Int Wound J. 2023 Dec 20.
    Visualizing the global trends of peptides in wound healing through an in-depth bibliometric analysis.
    Xinyan He, Yuchen Hu, Meiling Wu, Hong Li, Ling Ding, Shiqin Huang, Wen Wu, Ying Fan.
      Wound healing is a complicated and multistage biological process for the repair of damaged/injured tissues, which requires intelligent designs to provide comprehensive and convenient treatment. Peptide-based wound dressings have received extensive attention for further development and application due to their excellent biocompatibility and multifunctionality. However, the current lack of intuitive analysis of the development trend and research hotspots of peptides applied in wound healing, as well as detailed elaboration of possible research hotspots, restricted obtaining a comprehensive understanding and development in this field. The present study analysed publications from the Web of Science (WOS) Core Collection database and visualized the hotspots and current trends of peptide research in wound healing. Data between January 1st, 2003, and December 31st, 2022, were collected and subjected to a bibliometric analysis. The countries, institutions, co-authorship, co-citation reference, and co-occurrence of keywords in this subject were examined using VOSviewer and CiteSpace. We provided an intuitive, timely, and logical overview of the development prospects and challenges of peptide application in wound healing and some solutions to the major obstacles, which will help researchers gain insights into the investigation of this promising field.
    Keywords:  bibliometric analysis; peptide; research hotspots; visualisation; wound healing
    DOI:  https://doi.org/10.1111/iwj.14575
  22. Front Microbiol. 2023 ;14 1287003
    Global characteristics and trends in research on Candida auris.
    Qihui Wang, Shitong Cheng, Yinling Wang, Fushun Li, Jingjing Chen, Wei Du, Hui Kang, Zhongqing Wang.
       Introduction: Candida auris, a fungal pathogen first reported in 2009, has shown strong resistance to azole antifungal drugs and has caused severe nosocomial outbreaks. It can also form biofilms, which can colonize patients' skin and transmit to others. Despite numerous reports of C. auris isolation in various countries, many studies have reported contradictory results.
    Method: A bibliometric analysis was conducted using VOSviewer to summarize research trends and provide guidance for future research on controlling C. auris infection. The analysis revealed that the United States and the US CDC were the most influential countries and research institutions, respectively. For the researchers, Jacques F. Meis published the highest amount of related articles, and Anastasia P. Litvintseva's articles with the highest average citation rate. The most cited publications focused on clade classification, accurate identification technologies, nosocomial outbreaks, drug resistance, and biofilm formation. Keyword co-occurrence analysis revealed that the top five highest frequencies were for 'drug resistance,' 'antifungal susceptibility test,' 'infection,' 'Candida auris,' and 'identification.' The high-frequency keywords clustered into four groups: rapid and precise identification, drug resistance research, pathogenicity, and nosocomial transmission epidemiology studies. These clusters represent different study fields and current research hotspots of C. auris.
    Conclusion: The bibliometric analysis identified the most influential country, research institution, and researcher, indicating current research trends and hotspots for controlling C. auris.
    Keywords:  Candida auris; bibliometric analysis; drug resistance; nosocomial outbreaks; research trends
    DOI:  https://doi.org/10.3389/fmicb.2023.1287003
  23. Account Res. 2023 Dec 18. 1-29
    Correlation between journal metrics-based academic evaluation and researchers' ethics.
    Lidija Ivanović, Philipp Baaden, Miloš Jovanović, Dragan Ivanović.
      The "publish or perish" approach has become an integral part of an academic's life when seeking positions, striving for promotions, or competing for funding. This approach often hinges on journal-based metrics which push researchers to seek publication in journals indexed in the Web of Science. Due to the pressure to publish a certain number of publications in journals indexed in the Web of Science, researchers might attempt to find a journal with a lower impact factor, i.e., less popular and visible journals in the scientific community. Even more concerning is the fact that researchers might publish their results in predatory journals. This paper analyzes the consequence of introducing a journal indicators-based academic evaluation by analyzing productivity and publication patterns of researchers. Moreover, this paper investigates the correlation between journal-based academic evaluation rules and researchers' ethics. The analysis is based on bibliometric data collected from the Web of Science database. The case study subject is the Serbian research landscape before and after the introduction of a journal metrics-based academic evaluation.
    Keywords:  Academic evaluation rules; ethics; journal selection; publication patterns; publish or perish
    DOI:  https://doi.org/10.1080/08989621.2023.2295415
  24. Front Endocrinol (Lausanne). 2023 ;14 1287101
    Bibliometric analysis and visualization of endocrine therapy for breast cancer research in the last two decade.
    Dasong Wang, Yan Yang, Lei Yang, Hongwei Yang.
       Background: Breast cancer endocrine therapy research has become a crucial domain in oncology since hormone receptor-positive breast cancers have been increasingly recognized, and targeted therapeutic interventions have been advancing over the past few years. This bibliometric analysis attempts to shed light on the trends, dynamics, and knowledge hotspots that have shaped the landscape of breast cancer endocrine therapy research between 2003 and 2022.
    Methods: In this study, we comprehensively reviewed the scientific literature spanning the above-mentioned period, which included publications accessible through the database of the Web of Science (WOS) and the National Center for Biotechnology Information (NCBI). Next, a systematic and data-driven analysis supported by sophisticated software tools was conducted, such that the core themes, prolific authors, influential journals, prominent countries, and critical citation patterns in the relevant research field can be clarified.
    Results: A continuous and substantial expansion of breast cancer endocrine therapy research was revealed over the evaluated period. A total of 1,317 scholarly articles were examined. The results of the analysis suggested that research on endocrine therapy for breast cancer has laid a solid basis for the treatment of hormone receptor-positive breast cancer. From a geographical perspective, the US, the UK, and China emerged as the most active contributors, illustrating the global impact of this study. Furthermore, our analysis delineated prominent research topics that have dominated the discourse in the past two decades, including drug therapy, therapeutic efficacy, molecular biomarkers, and hormonal receptor interactions.
    Conclusion: This comprehensive bibliometric analysis provides a panoramic view of the ever-evolving landscape of breast cancer endocrine therapy research. The findings highlight the trajectory of past developments while signifying an avenue of vast opportunities for future investigations and therapeutic advancements. As the field continues to burgeon, this analysis will provide valuable guidance for to researchers toward pertinent knowledge hotspots and emerging trends, which can expedite the discoveries in the realm of breast cancer endocrine therapy.
    Keywords:  bibliometric analysis; biclustering analysis; breast cancer; endocrine therapy; visualization
    DOI:  https://doi.org/10.3389/fendo.2023.1287101
  25. Aesthetic Plast Surg. 2023 Dec 21.
    Top 50 Highly Cited Publications in Facelift Surgery: A 50-Year Bibliometric Analysis Review.
    Abdulmalek W Alhithlool, Abdullah A Al Qurashi, Ibrahim R Halawani, Sarah W Alkhonizy, Nouf Z AlBattal, Lama A Alkhwildi, Nawaf Alhindi, Talal A Albalawi, Omar Fouda Neel, Hatan Mortada.
       INTRODUCTION: Facelift surgery, also known as rhytidectomy, is a commonly performed procedure to address aging-related changes in the face and neck. Over the years, its techniques and methodologies have evolved. This study aimed to provide a bibliometric analysis of the top 50 most cited publications related to facelift surgery over a fifty-year period (1973-2023).
    METHODS: The authors obtained data from the Web of Science Core Collection on July 15, 2023. Using a predefined search strategy, the most cited articles from 1973 to 2023 on facelift surgery were identified. The publications were analyzed for their type of study, journal of publication, geographic origin, and primary outcomes. Furthermore, the authorship gender distribution was assessed.
    RESULTS: The majority of the publications (34 out of 50) were published in the "Plastic and Reconstructive Surgery" journal. The USA contributed to 72% of the research, followed by the UK, Mexico, Australia, and Germany. The primary outcomes varied from surgical techniques, anatomical studies, risk factors, patient-specific outcomes, and facial rejuvenation techniques, to comparative and historical progression of techniques. Notably, male authors dominated the field with 47 out of 50 papers having both a first and senior male author.
    CONCLUSION: Facelift surgery has seen substantial research development over the past fifty years. The USA has been at the forefront of this research, with a predominant focus on surgical techniques and anatomical studies. Male dominance in authorship indicates potential scope for increased gender diversity in this specialty. Annual updates are recommended for continued insights.
    LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  Bibliometrics; Face tightness; Facelift; Facial rejuvenation; Rhytidectomy; Rhytidoplasty
    DOI:  https://doi.org/10.1007/s00266-023-03752-x
  26. Front Neuroinform. 2023 ;17 1310400
    Systematic bibliometric and visualized analysis of research hotspots and trends in artificial intelligence in autism spectrum disorder.
    Qianfang Jia, Xiaofang Wang, Rongyi Zhou, Bingxiang Ma, Fangqin Fei, Hui Han.
       Background: Artificial intelligence (AI) has been the subject of studies in autism spectrum disorder (ASD) and may affect its identification, diagnosis, intervention, and other medical practices in the future. Although previous studies have used bibliometric techniques to analyze and investigate AI, there has been little research on the adoption of AI in ASD. This study aimed to explore the broad applications and research frontiers of AI used in ASD.
    Methods: Citation data were retrieved from the Web of Science Core Collection (WoSCC) database to assess the extent to which AI is used in ASD. CiteSpace.5.8. R3 and VOSviewer, two online tools for literature metrology analysis, were used to analyze the data.
    Results: A total of 776 publications from 291 countries and regions were analyzed; of these, 256 publications were from the United States and 173 publications were from China, and England had the largest centrality of 0.33; Stanford University had the highest H-index of 17; and the largest cluster label of co-cited references was machine learning. In addition, keywords with a high number of occurrences in this field were autism spectrum disorder (295), children (255), classification (156) and diagnosis (77). The burst keywords from 2021 to 2023 were infants and feature selection, and from 2022 to 2023, the burst keyword was corpus callosum.
    Conclusion: This research provides a systematic analysis of the literature concerning AI used in ASD, presenting an overall demonstration in this field. In this area, the United States and China have the largest number of publications, England has the greatest influence, and Stanford University is the most influential. In addition, the research on AI used in ASD mostly focuses on classification and diagnosis, and "infants, feature selection, and corpus callosum are at the forefront, providing directions for future research. However, the use of AI technologies to identify ASD will require further research.
    Keywords:  CiteSpace; VOSviewer; artificial intelligence; autism spectrum disorder; bibliometric; data visualization
    DOI:  https://doi.org/10.3389/fninf.2023.1310400
  27. J Clin Pathol. 2023 Dec 12. pii: jcp-2023-209203. [Epub ahead of print]
    Evolving educational landscape in pathology: a comprehensive bibliometric and visual analysis including digital teaching and learning resources.
    Luca Cima, Nicole Bussola, Lewis A Hassell, Tim-Rasmus Kiehl, Casey Schukow, Norman Zerbe, Enrico Munari, Evelin Torresani, Mattia Barbareschi, Matthew J Cecchini, Vito Cirielli, Francesca Pagliuca, Muhammad Ahsan, Sambit K Mohanty, Ernesto Arbitrio, Griffin Hughes, Kamran M Mirza.
       AIMS: Pathology education is a core component of medical training, and its literature is critical for refining educational modalities. We performed a cross-sectional bibliometric analysis to explore publications on pathology education, focusing on new medical education technologies.
    METHODS: The analysis identified 64 pathology journals and 53 keywords. Relevant articles were collected using a web application, PaperScraper, developed to accelerate literature search. Citation data were collected from multiple sources. Descriptive statistics, with time period analysis, were performed using Microsoft Excel and visualised with Flourish Studio. Two article groups were further investigated with a bibliometric software, VOSViewer, to establish co-authorship and keyword relationships.
    RESULTS: 8946 citations were retrieved from 905 selected articles. Most articles were published in the last decade (447, 49.4%). The top journals were Archives of Pathology & Laboratory Medicine (184), Human Pathology (122) and the American Journal of Clinical Pathology (117). The highest number of citations was found for Human Pathology (2120), followed by Archives of Pathology & Laboratory Medicine (2098) and American Journal of Clinical Pathology (1142). Authors with different backgrounds had the greatest number of articles and citations. 12 co-authorship, 3 keyword and 8 co-citation clusters were found for the social media/online resources group, 8 co-authorship, 4 keyword and 7 co-citation clusters for the digital pathology/virtual microscopy/mobile technologies group.
    CONCLUSIONS: The analysis revealed a significant increase in publications over time. The emergence of digital teaching and learning resources played a major role in this growth. Overall, these findings underscore the transformative potential of technology in pathology education.
    Keywords:  education; education, medical; information technology
    DOI:  https://doi.org/10.1136/jcp-2023-209203
  28. Medicine (Baltimore). 2023 Dec 22. 102(51): e36460
    Research hotspots and trends in the relationship between genetics and major depressive disorder: A scientometric analysis from 2003 to 2023.
    Ziwei Zhao, Yanyan Li, Peili Wang, Ran Zhang, Zhongbiao Nie.
      To determine current research objectives and predict future trends in studies on the relationship between genetics and major depressive disorder (MDD). We collected the publications in the last 20 years (2003-2023) related to genetics and MDD in the Web of Science database, and applied Citespace to assess the knowledge mapping. The number of manuscripts about genetics and MDD totaled 9200, with a faster increase after 2013. The country, institution, and author with the most publications are the USA, the University of London, and Serretti, Alessandro. BIOL PSYCHIAT published the most articles in this field. In addition, the most co-cited reference is Sullivan PF (2000) (673). Genetic and MDD research, including the hippocampus, and HPA axis may become the focus of research in the future. Based on a 20-year scientometric investigation, we know the USA, China, and Germany have emerged as the important research forces in this discipline. The strongest collaborations between developed countries and renowned institutions are beneficial to the advancement of genetic and MDD research. Serotonin is the strongest citation bursts keyword.
    DOI:  https://doi.org/10.1097/MD.0000000000036460
  29. Basic Clin Neurosci. 2023 Mar-Apr;14(2):14(2): 273-287
    Research Focuses and Trends in Multiple Sclerosis: A Scientometric Analysis.
    Yuh-Shan Ho, Maryam Shekofteh, Abdorreza Naser Moghadasi.
       Introduction: The purpose of this study is to analyze the multiple sclerosis research in Science Citation Index-Expanded from 1992 to 2019 in order to determine the top features, trends, and topics.
    Methods: In this scientometric study, research population was all articles related to multiple sclerosis in the Web of Science from 1992 to 2019. These articles were retrieved from the Science Citation Index-Expanded and analyzed based on various indicators and characteristics.
    Results: There was a significant increase in the number of articles from 408 in 1992 to 2756 in 2019. A sum of 42,112 articles related to multiple sclerosis has been published in 3,032 journals, which were classified among the 131 Web of Science categories. The top two categories were clinical neurology and neurosciences. Multiple Sclerosis Journal published the most articles. Articles published in the Neurology Journal also had the highest citation per publication. Most of the articles were in English, while 23 other languages were used in the articles. Articles in Japanese and English with 7 and 6.9 authors have a higher average of authors than articles in other languages. English language articles received more citations than articles in other languages. The frequency of used keywords in title, abstract, author keywords, and keywords plus analysis showed that "therapy", "disability", "neurodegeneration", "demyelination" and "MRI" show an increasing trend in the multiple sclerosis articles.
    Conclusion: The result of this study can help the policy makers and researchers realize the panorama of multiple sclerosis research and design future research.
    Highlights: The number of multiple sclerosis (MS) articles shows a growing trend, from 1992 to 2019.MS is being studied by researchers worldwide in the articles with 23 different languages.Symptoms, diagnosis, the ways to reduce symptoms, models, and epidemiology are main categories of MS articles.The main foci and trend in MS articles, is "therapy" of the disease.
    Plain Language Summary: In this article we studied the features, trends and topics of MS articles from 1992 to 2019. The 42.112 articles retrieved from the web of Sciences database and analyzed. We found that the number of articles increased from 408 in 1992 to 2756 in 2019. These articles have been published in 3032 journals in 23 languages, shows that this subject is an important subject all around the world. We studied the frequency of used keywords in articles and found that some keywords such as "therapy", "disability", "neurodegeneration", "demyelination" and "MRI" show an increasing trend. Between them, therapy is the most frequent keyword. This shows that this subject is very important for researchers and they are working hard on it. We also studied the main categories of MS articles and found that the research on MS is concentrated around five main categories: symptoms, diagnosis, the ways to reduce the symptoms of the disease such as therapy or rehabilitation, and prevalence of the MS. The results of this study can help the researchers and policy makers realize the panorama of multiple sclerosis research and design future research.
    Keywords:  Multiple sclerosis; Scientometrics; Web of science core collection; Word analysis; Word cluster
    DOI:  https://doi.org/10.32598/bcn.2021.3495.1
  30. Front Mol Biosci. 2023 ;10 1302016
    Mapping knowledge structure and themes trends of cancer-associated fibroblasts: a text-mining study.
    Kunming Cheng, Wanqing Li, Haiyang Wu, Cheng Li.
      Introduction: Cancer-associated fibroblasts (CAFs) constitute an important component of the tumor microenvironment, participating in various facets of cancer advancement and being recognized as contributors to tumor immune evasion. The role of CAFs in various tumor types has attracted increasing attention recently. In this work, we conducted a comprehensive bibliometric analysis to uncover research trajectories and highlight emerging areas in the field of CAFs. Methods: A systematic search was performed within the Web of Science Core Collection to identify articles/reviews on CAFs published between 2000 and 2023. Leveraging advanced bibliometric tools such as VOSviewer, CiteSpace, and online website, we examined and visualized publication trends, geographic contributions, institutional affiliations, journal prominence, author collaborations, and noteworthy references, keywords, and genes. Results: Our analysis included 5,190 publications, indicating a rapid growth trend in both annual publications and citations related to CAFs. China and the United States emerged as the foremost contributors in terms of publications, funding agencies, and international collaborations. Breast cancer was the most studied tumor, followed by colorectal cancer, pancreatic cancer, prostate cancer, and gastric cancer. Based on co-occurrence and bursting keywords, we identified the following research topics including immune cells (T cells, B-cells, tumor-associated macrophages), tumor immune microenvironment (antitumor immunity, immune infiltration, immunosuppression), immunotherapy (PD-L1), microRNAs (miRNA), extracellular vesicles (exosome), multiple tumors (pancreatic ductal adenocarcinoma, bladder cancer, head and neck squamous cell carcinoma), antitumor agents (gemcitabine, cisplatin resistance), bioinformatics (pan-cancer), epithelial-mesenchymal transition (stemness), FAPI PET/CT, DNA methylation, etc., may receive sustained attention in the future. Furthermore, TGFB1, IL-6, TNF, TP53, and VEGFA emerged as the top 5 genes that have garnered the greatest research attention in the field of CAFs. The KEGG enrichment analysis highlighted that the top 20 most studied genes were mainly associated with HIF-1 and Toll-like receptor signaling pathways. Discussion: In sum, our bibliometric analysis offers a comprehensive overview of the research landscape in the field of CAFs. It encompasses the current state, evolving patterns, and prospective avenues of exploration, with special attention to the potential advancements in tumor immune microenvironment.
    Keywords:  VOSviewer; bibliometrics; cancer-associated fibroblasts; citespace; hotspots
    DOI:  https://doi.org/10.3389/fmolb.2023.1302016
  31. Medicine (Baltimore). 2023 Dec 15. 102(50): e34511
    Circle packing charts generated by ChatGPT to identify the characteristics of articles by anesthesiology authors in 2022: Bibliometric analysis.
    Sam Yu-Chieh Ho, Tsair-Wei Chien, Willy Chou.
       BACKGROUND: The ChatGPT (Open AI, San Francisco, CA), denoted by the Chat Generative Pretrained Transformer, has been a hot topic for discussion over the past few months. A verification of whether the code for drawing circle packing charts (CPCs) with R can be generated by ChatGPT and used to identify characteristics of articles by anesthesiology authors is needed. This study aimed to provide insights into article characteristics in the field of anesthesiology and to highlight the potential of ChatGPT for data visualization techniques (e.g., CPCs) in bibliometric analysis.
    METHODS: A total of 23,012 articles were indexed in PubMed in 2022 by authors in the field of anesthesiology. The code for drawing CPCs with R was generated by ChatGPT and then modified by the authors to identify the characteristics of articles in 2 forms: 23,012 and 100 top-impact factors in journals (T100IF). Using CPCs and 3 other visualizations-network charts, impact beam plots, and Sankey diagrams-we were able to display article features commonly used in bibliometric analysis. The author-weighted scheme and absolute advantage coefficient were used to assess dominant entities, such as countries, institutes, authors, and themes (defined by PubMed and MeSH terms).
    RESULTS: Our findings indicate that: further modifications should be made to the code generated by ChatGPT for drawing CPCs in R; publications in the field of anesthesiology are dominated by China, followed by the United States and Japan; Capital Medical University (China) and Showa University Hospital (Japan) dominate research institutes in terms of publications and IF, respectively; and COVID-19 is the most frequently reported theme in T100IF, accounting for 29%.
    CONCLUSIONS: No such articles with CPCs regarding bibliometrics have ever been found in PubMed. The code for drawing CPCs with R can be generated by ChatGPT, but further modification is required for implementation in bibliometrics. CPCs should be used in future studies to identify the characteristics of articles in other areas of research rather than limiting them to anesthesiology, as we did in this study.
    DOI:  https://doi.org/10.1097/MD.0000000000034511
  32. Front Psychiatry. 2023 ;14 1229580
    Early predictors in language-based learning disabilities: a bibliometric analysis.
    Maryam Alabbad, Muhammad Ajmal Khan, Nadeem Siddique, Jaber Abou Hassan, Shahid Bashir, Turki Abualait.
       Introduction: Language-based learning disabilities (LBLD) refers to a spectrum of neurodevelopmental-associated disorders that are characterized by cognitive and behavioral differences in comprehending, processing and utilizing spoken and/or written language. The focus of this work was on identifying early predictors of three main specific LBLD including dyslexia, dyscalculia, and dysgraphia.
    Methods: The Web of Science (WoS) was searched for literature related to (neurocognitive, neurophysiological, and neuroimaging) measurements used to identify early predictors of LBLD from 1991 to 25 October 2021. A retrospective bibliometric analysis was performed to analyze collaboration among countries, institutions, authors, publishing journals, reference co-citation patterns, keyword co-occurrence, keyword clustering, and burst keywords using Biblioanalytics software.
    Results: In total, 921 publications related to the identification of LBLD using (neurocognitive, neurophysiological, and neuroimaging) modalities were included. The data analysis shows a slow growth in research on the topic in the 90s and early 2000 and growing trend in recent years. The most prolific and cited journal is Neuroimage, followed by Neuropsychologia. The United States and Finland's Universities Jyvaskyla and Helsinki are the leading country and institution in this field, respectively. "Neuroimaging," "brain," "fMRI," "cognitive predictor," "comorbidity," "cortical thickness" were identified as hotspots and trends of (neurocognitive, neurophysiological, and neuroimaging) modalities in the identification of LBLD.
    Discussion: Early predictors of LBLDs would be useful as targets for specific prevention and intervention programs to be implemented at very young ages, which could have a significant clinical impact. A novel finding of neuroimaging predictors combined with neurocognitive and neuropsychological batteries may have implications for future research.
    Keywords:  dyscalculia; dysgraphia; dyslexia; early predictors; modalities
    DOI:  https://doi.org/10.3389/fpsyt.2023.1229580
  33. Math Biosci Eng. 2023 Nov 10. 20(12): 20405-20421
    Research hotspots and trends of artificial intelligence in rheumatoid arthritis: A bibliometric and visualized study.
    Di Zhang, Bing Fan, Liu Lv, Da Li, Huijun Yang, Ping Jiang, Fangmei Jin.
      Artificial intelligence (AI) applications on rheumatoid arthritis (RA) are becoming increasingly popular. In this bibliometric study, we aimed to analyze the characteristics of publications relevant to the research of AI in RA, thereby developing a thorough overview of this research topic. Web of Science was used to retrieve publications on the application of AI in RA from 2003 to 2022. Bibliometric analysis and visualization were performed using Microsoft Excel (2019), R software (4.2.2) and VOSviewer (1.6.18). The overall distribution of yearly outputs, leading countries, top institutions and authors, active journals, co-cited references and keywords were analyzed. A total of 859 relevant articles were identified in the Web of Science with an increasing trend. USA and China were the leading countries in this field, accounting for 71.59% of publications in total. Harvard University was the most influential institution. Arthritis Research & Therapy was the most active journal. Primary topics in this field focused on estimating the risk of developing RA, diagnosing RA using sensor, clinical, imaging and omics data, identifying the phenotype of RA patients using electronic health records, predicting treatment response, tracking the progression of the disease and predicting prognosis and developing new drugs. Machine learning and deep learning algorithms were the recent research hotspots and trends in this field. AI has potential applications in various fields of RA, including the risk assessment, screening, early diagnosis, monitoring, prognosis determination, achieving optimal therapeutic outcomes and new drug development for RA patients. Incorporating machine learning and deep learning algorithms into real-world clinical practice will be a future research hotspot and trend for AI in RA. Extensive collaboration to improve model maturity and robustness will be a critical step in the advancement of AI in healthcare.
    Keywords:   artificial intelligence ; hotspots ; research ; rheumatoid arthritis ; trends
    DOI:  https://doi.org/10.3934/mbe.2023902
  34. J Relig Health. 2023 Dec 18.
    Reflection on Ramadan Fasting Research Related to Sustainable Development Goal 3 (Good Health and Well-Being): A Bibliometric Analysis.
    Katia AbuShihab, Khaled Obaideen, Mohamad Alameddine, Refat Ahmad Fawzi Alkurd, Husam M Khraiwesh, Yara Mohammad, Dana N Abdelrahim, Mohamed I Madkour, MoezAlIslam E Faris.
      There is a large body of research on Ramadan intermittent fasting (RIF) and health in Muslim communities, that can offer insights to promote the achievement of Sustainable Development Goal 3 (SDG 3), which encompasses good health and well-being. Based on recent bibliometric evidence, we hypothesized that RIF research is highly relevant to SDG 3, particularly Targets 3.1, 3.2, 3.4, and 3.5. Therefore, this bibliometric study quantified RIF literature supporting SDG 3 and associated targets over the past seven decades and explored themes and trends. All types of research articles were extracted from the Scopus database from inception to March 2022. Microsoft Excel, Biblioshiny, and VOSviewer were used to qualitatively and quantitatively examine RIF research trends supporting SDG 3 and associated targets. We identified 1729 relevant articles. The number of publications notably increased since 1986, with a dramatic increase in 2019-2020. RIF research predominantly supported Target 3.4 (reducing risk for non-communicable diseases), with research hotspots being diabetes, diabetes medications, pregnancy, physiology, metabolic diseases, and obesity and metabolism. This target was also the most commonly supported by dedicated authors and institutions publishing on RIF, whereas other SDG 3 targets were negligibly addressed in comparison. Our comprehensive bibliometric analysis of RIF literature showed growing support for SDG 3 through positive contributions to half of the SDG 3 targets, although Target 3.4 received the most attention. We also identified knowledge gaps that may shape further research directions on RIF and promote the achievement of SDG 3 in Muslim communities.
    Keywords:  Bibliometric analysis; Citation analysis; Medical journals; Ramadan; SDG 3; Scientometric; Text mining
    DOI:  https://doi.org/10.1007/s10943-023-01955-9
  35. Heliyon. 2023 Dec;9(12): e22499
    Trends in physical activity research for breast cancer - A bibliometric analysis of the past ten years.
    Brayan E Patiño-Palma, Luis López-Montoya, Rafael Escamilla-Ugarte, Alejandro Gómez-Rodas.
       Introduction: Cancer, particularly breast cancer, is a significant cause of death worldwide, and physical activity has been shown to reduce the risk of developing cancer and improve the prognosis of patients diagnosed with cancer. However, there is a lack of detailed analysis of publications related to physical activity in breast cancer patients, hindering the provision of strong evidence in this area.
    Materials and methods: The Core Collection database of Web of Science (WoS) was used as the source of the bibliography, with a search conducted on October 16, 2023. The search strategy used the terms "Physical Activity" and "Breast Cancer" or "Lymphedema," identifying articles published between 2012 and 2022. The bibliometric analysis focused on three dimensions, including scientific production and delivery, scientific collaboration, and bibliometric evaluation at the individual level. We performed the data analysis with Bibiometrix, an open-source tool integrated with R that allows a complete analysis of the behavior of the scientific literature.
    Results: A total of 979 publications related to physical activity o exercise in breast cancer (974 article, 1 data paper, 2 article early access y 2 proceedings paper), with an increasing trend in the number of articles published over the years. The most common research topics included "quality of life", "woman", "survivors", and the impact of physical activity on the risk of cancer recurrence. The United States was the most productive country in this area, and the Journal "Supportive Care in Cancer" was the most common journal to publish on this topic.
    Conclusion: This bibliometric analysis provides insight into publication trends and common research topics in the area of physical activity and breast cancer. The results can be beneficial in guiding future physical rehabilitation research inquiries and providing information to funding agencies on areas of greatest research opportunities.
    Keywords:  Breast neoplasms; Physical activity; Publication trends; Scientific research; Scientometrics
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e22499
  36. Clin Oral Investig. 2023 Dec 22. 28(1): 14
    Evolution, current status, and future trends of maxillary skeletal expansion: a bibliometric analysis.
    Zhiyuan Feng, Minmin Si, Hao Fan, Yin Zhang, Rui Yuan, Zhaonan Hao.
       OBJECTIVES: The study aims to conduct a bibliometric analysis on maxillary skeletal expansion to elucidate the evolution and current status and predict future research hotspots and trends.
    MATERIAL AND METHODS: A search was conducted in the Web of Science Core Collection at the University of Hong Kong's electronic library using the query "(TS = maxillary expansion) AND (TS = skeletal expansion)." The resulting literature data were imported into CiteSpace 6.2.R4 and VOS viewer software to analyze authorship, countries, institutions, keywords, etc. RESULTS: A total of 923 articles were analyzed. The research in this field has shown a steady growth, with a significant increase since 2019. The USA and Italy have played prominent roles in contributing to the publication volume and strengthening collaborative exchanges. Clustering labels provide directions for in-depth analysis of the literature.
    CONCLUSIONS: (1) MARPE (miniscrew-assisted rapid palatal expansion) and SARME (surgically assisted rapid maxillary expansion) have gained widespread attention and become research hotspots due to their applicability in adults whose growth and development have ceased, while still producing favorable skeletal effects. (2) In addition to widening the maxillary arch, maxillary expansion techniques have shown significant effects on increasing nasal cavity width and volume. However, there is still controversy regarding whether they can effectively improve the deviated nasal septum. (3) Maxillary skeletal expansion techniques have been shown to increase upper airway volume and improve breathing, making them potentially valuable in the treatment of obstructive sleep apnea (OSA).
    CLINICAL RELEVANCE: This study can provide cutting-edge clinical recommendations for healthcare professionals to better formulate clinical strategies.
    Keywords:  Bibliometric analysis; Maxillary expansion; Nasal cavity; Skeletal expansion; Upper airway
    DOI:  https://doi.org/10.1007/s00784-023-05430-3
  37. Zhonghua Yi Xue Za Zhi. 2023 Dec 26. 103(48): 3959-3966
    [The characteristics and citation analysis of the publications in the National Medical Journal of China from 2017 to 2019].
    J R Zhang, P J Sun, M X Liang, Z W Zhang, X Z Lyu.
      Objective: To analyze the characteristics and citation of National Medical Journal of China (NMJC) from 2017 to 2019, and provide reference for the development of the journal. Methods: All the literature published in NMJC during the period 2017 to 2019 was selected as the research objects, and the citation frequency data in Chinese core periodicals of science and technology from January 2018 to December 2021 were obtained through Institute of Scientific and Technical Information of China. The main indicators included the citation rate of published articles, average citation frequency of articles, citation status of individual papers, high citation authors and their affiliations from 2017 to 2019. Results: A total of 2 694 articles were published in 21 columns of NMJC from 2017 to 2019. The total number of published pages was 11 689, and the average number of articles was 4.34 pages. The total number of cited papers was 1 849, accounting for 68.63%. Among them, 845 papers were not cited, accounting for 31.37%. The total citation times was 6 578, with an average citation of 2.44 times. The highest citation frequency of a single paper was 217 times. A total of 54.27% articles obtained fund support, and the cited rate (72.78%) was slightly higher than that of articles without fund support (63.72%). Standard and specification articles were cited 1 817 times, with a citation rate of 96.67%, and 66 articles were cited more than 10 times. The columns with more than 30 articles but all cited less than 1 time included case report and difficult case analysis. The first author was from 31 provinces (autonomous regions, municipalities directly under the Central Government) in China. There were 21 corresponding authors whose papers have been cited more than 30 times, and 18 of them were from major hospitals and science academies in Beijing. Conclusions: NMJC has a wide coverage of contributions and strong academic influence during the period 2017 to 2019. The cited frequency of standard and specification articles is high, while case report and difficult case analysis evaluation column articles have very low cited frequencies. Therefore, NMJC should further adjust column setting, improve the academic quality, reduce the number of zero cited papers, and thus enhance the influence of the magazine.
    DOI:  https://doi.org/10.3760/cma.j.cn112137-20231106-01027
  38. Braz Dent J. 2023 Nov-Dec;34(6):pii: S0103-64402023000600100. [Epub ahead of print]34(6): 100-109
    Leadership through a gender lens: Disparities in Dental Research.
    Luisa Gatti-Reis, Flávio Freitas Mattos, Isabela Almeida Pordeus, Paulo Antônio Martins-Júnior, Danielle Carvalho de Oliveira Coutinho, Matheus França Perazzo, Saul Martins Paiva.
      This study aimed to analyze the 100 most-cited papers in Dentistry, with a focus on female leadership in dental research. Papers were retrieved from the Web of Science Core Collection (WoS- CC) in the category 'Dentistry, Oral Surgery & Medicine'. Gender was assessed through WoS-CC, Scopus, ResearchGate, social media, institutional websites, and software that assigns gender according to first names (https://genderapi.io). Characteristics of authors in leadership roles were retrieved, such as affiliation, publication history, citations, H factor, and i500. The 100 most-cited papers in Dentistry were authored by 394 researchers, 326 (82.7%) men, and 68 (17.3%) women - there were 4.8 male authors for each female. Among the lead authors, there were 11.3 males for each female. Among female senior authors, there were 7 males for each female. Among lead/senior authors of the 100 most-cited papers (first and last authors, respectively), 18 were women. There was an increase in the participation of women in the top cited papers regardless of authorship role across the six decades, with a peak of two female authors in the first decade of the 21st century. For female authors in leadership roles, their publication history shows the time between their first and last papers in WoS-CC ranged from 4 to 42 years for lead authors and 1 to 39 years for senior authors. Women were found to be largely underrepresented as leaders of the 100 most-cited papers, highlighting pervasive gender inequalities in dental research publications.
    DOI:  https://doi.org/10.1590/0103-644020230555959
  39. Int Wound J. 2023 Dec 20.
    Visualization of the relationship between macrophage and wound healing from the perspective of bibliometric analysis.
    Qiang Guo, Wanqing Li, Ruijie Xie, Yulin Wang, Yuchen Xie, Kunming Cheng, Zhiming Sun.
      Macrophages play a crucial role in aiding all phases of the wound-healing process and has garnered increasing attention recently. Although a substantial body of related studies has been published, there remains a lack of comprehensive bibliometric analysis. In this study, we collected 4296 papers from the Web of Science Core Collection database. Three tools including CiteSpace, VOSviewer and one online analytical platform were employed to conduct bibliometric analysis and data visualization. Our results revealed that the annual number of publications related to macrophage and wound healing has increased exponentially with the year. The United States and China stand as the primary driving forces within this field, collectively constituting 58.2% of the total publication output. The application of biomaterials was one of the most concerned research areas in this field. According to references analysis, the current research focus has shifted to diabetic wound healing and regulating macrophage polarization. Based on the keywords analysis, we identified the following research frontiers in the future: exosomes and other extracellular vesicles; bio-derived materials and drug delivery methods such as nanoparticles, scaffolds and hydrogels; immunomodulation and macrophage polarization in the M2-state; chronic wounds, particularly those associated with diabetes; antimicrobial peptides; and antioxidant. Additionally, TNF, IL-6, IL-10, TGF-β1 and VEGF ranked as the five genes that have garnered the most research attention in the intersection of macrophage and wound healing. All in all, our findings offered researchers a holistic view of the ongoing progress in the field of macrophages and wound healing, serving as a valuable reference for scholars and policymakers in this domain.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; macrophage; wound healing
    DOI:  https://doi.org/10.1111/iwj.14597
  40. World J Gastroenterol. 2023 Dec 07. 29(45): 6017-6021
    Intestinal barrier in inflammatory bowel disease: A bibliometric analysis.
    Wen-Yu Luan, Zhe Yang, Xiao-Dong Chen, Tong-Tong Zhang, Fang Zhang, Yan-Dong Miao.
      The primary objective of this investigation was to examine the evolving trajectories and pivotal focal points within the domain of research on intestinal barriers with regard to inflammatory bowel disease (IBD). Publications germane to the intestinal barrier in the context of IBD were procured from the Science Citation Index Expanded within the Web of Science Core Collection database. Bibliometric scrutiny and visualization were executed employing the R package "bibliometrix" through the R software platform (version: 4.3.0). A comprehensive compilation of 7344 English-language articles spanning from January 1, 2001 to December 31, 2021 was meticulously identified and included in the analysis. Remarkably, China emerged as the preeminent force in the realm of intestinal barrier research in relation to IBD. The significance of the intestinal barrier in the context of IBD has been progressively and comprehensively acknowledged. This recognition has ushered in a fresh therapeutic perspective that offers the promise of enhancing the management of inflammation and prognostication.
    Keywords:  Bibliometric analysis; Bibliometrix; Gastroenterology; Inflammatory bowel disease; Intestinal barrier
    DOI:  https://doi.org/10.3748/wjg.v29.i45.6017
  41. J Nurs Scholarsh. 2023 Dec 22.
    Big data research in nursing: A bibliometric exploration of themes and publications.
    Bo Li, Kun Du, Guanchen Qu, Naifu Tang.
       AIMS: To comprehend the current research hotspots and emerging trends in big data research within the global nursing domain.
    DESIGN: Bibliometric analysis.
    METHODS: The quality articles for analysis indexed by the science core collection were obtained from the Web of Science database as of February 10, 2023.The descriptive, visual analysis and text mining were realized by CiteSpace and VOSviewer.
    RESULTS: The research on big data in the nursing field has experienced steady growth over the past decade. A total of 45 core authors and 17 core journals around the world have contributed to this field. The author's keyword analysis has revealed five distinct clusters of research focus. These encompass machine/deep learning and artificial intelligence, natural language processing, big data analytics and data science, IoT and cloud computing, and the development of prediction models through data mining. Furthermore, a comparative examination was conducted with data spanning from 1980 to 2016, and an extended analysis was performed covering the years from 1980 to 2019. This bibliometric mapping comparison allowed for the identification of prevailing research trends and the pinpointing of potential future research hotspots within the field.
    CONCLUSIONS: The fusion of data mining and nursing research has steadily advanced and become more refined over time. Technologically, it has expanded from initial natural language processing to encompass machine learning, deep learning, artificial intelligence, and data mining approach that amalgamates multiple technologies. Professionally, it has progressed from addressing patient safety and pressure ulcers to encompassing chronic diseases, critical care, emergency response, community and nursing home settings, and specific diseases (Cardiovascular diseases, diabetes, stroke, etc.). The convergence of IoT, cloud computing, fog computing, and big data processing has opened new avenues for research in geriatric nursing management and community care. However, a global imbalance exists in utilizing big data in nursing research, emphasizing the need to enhance data science literacy among clinical staff worldwide to advance this field.
    CLINICAL RELEVANCE: This study focused on the thematic trends and evolution of research on the big data in nursing research. Moreover, this study may contribute to the understanding of researchers, journals, and countries around the world and generate the possible collaborations of them to promote the development of big data in nursing science.
    Keywords:  bibliometrics; big data; nursing; visual analysis
    DOI:  https://doi.org/10.1111/jnu.12954
  42. Harefuah. 2023 Dec;162(10): 677-680
    [ASPECTS AFFECTING PEDIATRIC OPHTHALMOLOGY AND STRABISMUS PUBLICATION TIMES].
    Einav Baharav-Shlezinger, Rasha Mosleh, Gil Ben-David, Eedy Mezer, Tamara Wygnanski-Jaffe.
       BACKGROUND: To better understand and analyze various aspects of scientific publication, bibliometric data analysis is useful.
    OBJECTIVES: An analysis of the factors associated with shorter publication times in pediatric ophthalmology and strabismus (POS) between the years 2002 and 2007, compared to 2014 and 2018.
    METHODS: In this retrospective bibliometric analysis, we analyzed 2,487 articles related to POS from the official websites of 8 preselected ophthalmology journals. Time from submission to acceptance, from acceptance to publication, and from submission to publication were calculated for each article.
    RESULTS: Median peer review durations were 156 days from submission to acceptance; 79 days from acceptance to publication, and 244 days from submission to publication. Journals such as the American Journal of Ophthalmology, JAMA Ophthalmology, and Strabismus reported the shortest time from submission to publication. Annually, all time intervals decreased, but in the first decade, the decline was significantly greater. The time between submission and acceptance of female senior authors increased during the first decade; however, this disappeared during the second decade.
    CONCLUSIONS: There was an improvement in most journals and the gender gap in senior authorship decreased with time.
    DISCUSSION: Since digital technology has rapidly developed over the past two decades, authors have been able to communicate with editorial and production teams more quickly and efficiently. Journal names and the gender of the last author are the main factors affecting publication times.
  43. Medicine (Baltimore). 2023 Dec 15. 102(50): e35377
    Global trends and future directions in online learning for medical students during and after the COVID-19 pandemic: A bibliometric and visualization analysis.
    Pei Zhang, Xiuyuan Li, Ying Pan, Haihun Zhai, Tian Li.
      This study explores the evolution of online learning research in the context of medical education during and following the COVID-19 pandemic. It aims to understand the principal focus areas, and trends that have emerged in this rapidly evolving landscape. A total of 2751 publications related to online learning were retrieved from the Web of Science Core Collection (WoSCC) from 2020 to 2022. Bibliometric analysis and visualization techniques were employed to comprehensively examine the landscape of online learning research. Publications, co-cited references, and keyword co-occurrence were analyzed to identify patterns and trends in research focus and collaboration networks. The significant surge in research output reveals the academic community's response to the pandemic. Various themes have emerged in online learning research, encompassing online teaching, flipped classrooms, mental health, and blended learning. The evolution trajectory of research has traversed 3 stages, reflecting a shift in research focus from immediate pandemic responses to more refined strategies and interdisciplinary perspectives. Keyword co-occurrence analysis was also conducted to show the effects of the COVID-19 pandemic on the research. The study underscores the global scholarly engagement, collaborative networks, and principal themes that have shaped the field. As medical education adapts to the shifting landscape, the trajectory of online learning research points toward increased learner autonomy, integration of advanced technologies, and interdisciplinary collaboration. This transformative shift promises to reshape medical education, equipping learners and educators with the tools needed to navigate the dynamic realm of modern healthcare education.
    DOI:  https://doi.org/10.1097/MD.0000000000035377
  44. Malawi Med J. 2022 Dec;34(4): 260-266
    Bibliometric analysis of three international journals on public health dentistry: A comparative study from 2011 to 2020.
    Gunjan Kumar, Payal Dash, Samikshya Jena.
       Background and Objective: The research question was to conduct a comparative analysis of articles published, citations, grants and authors co-occurence in three journals of Public health dentistry namely Journal of Public Health (JIF-1.821), Community Dentistry and Oral Epidemiology (JIF-3.803) and Community Dentistry Health(JIF-1.079). This study was triggered, because of the constant growth of the academic production of articles in the world. The objective of this study is to describe the design of studies published in the period 2011 - 2020 of the three mentioned journals.
    Material and Methods: A retrospective, observational, comparative study was conducted for JPHD, CDOE ad CDH. All issues of JPHD, CDH and CDOE from 2011 to 2020 were manual searched and also assessed through Scopus database. The data were organized and analyzed using software SPSS version 21.0; and citation mapping process using VOSviewer software.
    Results: A total of 1544 articles were retrieved from all the three journals. The largest number of manuscripts was published in the Community Dentistry and Oral Epidemiology journal. The pattern of study design in JPHD (65.69%) and CDH(74.79%) was majorly cross sectional studies followed by cohort studies(19.46%) and randomized controlled trials (8.34%) respectively. In all the three journals, maximum authors were more than three in number. Majority of the original research work focused on oral health such as oral health status, literacy, oral health quality of life.
    Conclusion: The publication pattern in all the three journals were interestingly related to each other; most articles published were original research work intending an enhanced inclination of researchers toward observational affirmations.
    Keywords:  Bibliometry; Dental Caries; Oral Health; Public Health Dentistry; Research
    DOI:  https://doi.org/10.4314/mmj.v34i4.6
  45. An Acad Bras Cienc. 2023 ;pii: S0001-37652023000601503. [Epub ahead of print]95(suppl 3): e20230823
    Spatial and Scientometric study of the Brazilian scientific production on Antarctic soils and permafrost.
    Ícaro S Vieira, Fábio S DE Oliveira, Roberto F M Michel.
      This article carried out the first scientometric and spatial analysis of Brazilian scientific production on Antarctic soils and permafrost, based on all publications available from the Scopus and Web of Science databases. Information on co-authorship, citation, research topics, and sampling sites was used to understand the social and theoretical structure as well as the spatial dynamics of this research field in Brazil over the last 25 years. We highlight that Brazil is presently, the main country to study the soils and permafrost of Maritime Antarctica, in addition to having an international robust and prolific production, with high impact on the literature, and widely distributed throughout the studied region. It was also possible to identify potential future international partners, new research locations and strategic research themes.
    DOI:  https://doi.org/10.1590/0001-3765202320230823
  46. Pharmaceutics. 2023 Dec 12. pii: 2762. [Epub ahead of print]15(12):
    Advances in Transdermal Drug Delivery Systems: A Bibliometric and Patent Analysis.
    Aniello Cammarano, Stefania Dello Iacono, Caterina Meglio, Luigi Nicolais.
      Transdermal drug delivery systems have become an intriguing research topic in healthcare technology and one of the most frequently developed pharmaceutical products in the global market. In recent years, researchers and pharmaceutical companies have made significant progress in developing new solutions in the field. This study sheds light on current trends, collaboration patterns, research hotspots, and emerging frontiers of transdermal drug delivery. Herein, a bibliometric and patent analysis of data recovered from Scopus and The Lens databases, respectively, is reported over the last 20 years. From 2000 to 2022, the annual global publications increased from 131 in 2000 to 659 in 2022. Researchers in the United States, China, and India produced the highest number of publications. Likewise, most patent applications have been filed in the USA, China, and Europe. The recovered patents are 7275, grouped into 2997 patent families, of which 314 were granted. This study could support the work of decision-makers, scientific managers, or scientists to create new business opportunities or save money, time, and intellectual capital, thereby defining when a research or technology project should be a priority or not.
    Keywords:  bibliometric analysis; controlled release; patent analysis; transdermal administration; transdermal drug delivery
    DOI:  https://doi.org/10.3390/pharmaceutics15122762
  47. Medicine (Baltimore). 2023 Dec 22. 102(51): e36703
    Opportunities and challenges of computer aided diagnosis in new millennium: A bibliometric analysis from 2000 to 2023.
    Di Wu, Jiachun Ni, Wenbin Fan, Qiong Jiang, Ling Wang, Li Sun, Zengjin Cai.
       BACKGROUND: After entering the new millennium, computer-aided diagnosis (CAD) is rapidly developing as an emerging technology worldwide. Expanding the spectrum of CAD-related diseases is a possible future research trend. Nevertheless, bibliometric studies in this area have not yet been reported. This study aimed to explore the hotspots and frontiers of research on CAD from 2000 to 2023, which may provide a reference for researchers in this field.
    METHODS: In this paper, we use bibliometrics to analyze CAD-related literature in the Web of Science database between 2000 and 2023. The scientometric softwares VOSviewer and CiteSpace were used to visually analyze the countries, institutions, authors, journals, references and keywords involved in the literature. Keywords burst analysis were utilized to further explore the current state and development trends of research on CAD.
    RESULTS: A total of 13,970 publications were included in this study, with a noticeably rising annual publication trend. China and the United States are major contributors to the publication, with the United States being the dominant position in CAD research. The American research institutions, lead by the University of Chicago, are pioneers of CAD. Acharya UR, Zheng B and Chan HP are the most prolific authors. Institute of Electrical and Electronics Engineers Transactions on Medical Imaging focuses on CAD and publishes the most articles. New computer technologies related to CAD are in the forefront of attention. Currently, CAD is used extensively in breast diseases, pulmonary diseases and brain diseases.
    CONCLUSION: Expanding the spectrum of CAD-related diseases is a possible future research trend. How to overcome the lack of large sample datasets and establish a universally accepted standard for the evaluation of CAD system performance are urgent issues for CAD development and validation. In conclusion, this paper provides valuable information on the current state of CAD research and future developments.
    DOI:  https://doi.org/10.1097/MD.0000000000036703
  48. J Plast Reconstr Aesthet Surg. 2023 Dec 12. pii: S1748-6815(23)00787-8. [Epub ahead of print]88 475-477
    A 10-year analysis of citations and impact factors in plastic surgery journals.
    Nicholas Moellhoff, Constanze Kuhlmann, Riccardo E Giunta.
      
    Keywords:  Academic plastic surgery; Journal citation report; Journal impact factor; Self citations; Total citations
    DOI:  https://doi.org/10.1016/j.bjps.2023.12.010
  49. Indian J Ophthalmol. 2024 Jan 01. 72(Suppl 1): S66-S74
    Bibliometric and visualized analysis of diabetic macular edema.
    Jin Wei, Yiyang Shu, Yimin Wang, Haiyun Liu.
       PURPOSE: Our aim was to identify recent research trends on diabetic macular edema (DME) and focus on publications from different countries, institutions, and authors.
    METHODS: We retrieved and analyzed data from January 1, 2003 to December 31, 2022 on the DME research field from the Web of Science Core Collection (WoSCC) database. Microsoft Excel and VOSviewer were applied to perform visualization analysis and evaluate the trends.
    RESULTS: A total of 4482 publications were identified, and the annual global publications increased steadily, from 36 to 390, during this period. The United States (1339 publications, 71,754 citations), Johns Hopkins University (176 publications, 17,015 citations), and Bressler NM (76 publications, 9621 citations) were the most influential and productive countries, institutions, and authors, respectively. The top 100 keywords were classified into five clusters: (1) therapy and adverse effects of DME; (2) clinical biomarkers of DME; (3) mechanistic research on DME; (4) improving bioavailability and efficacy; and (5) early diagnosis of diabetic complications. "Diabetic macular edema," "retinopathy," "ranibizumab," and "optical coherence tomography angiography" were the most frequent keywords. Regarding the average appearing years (AAYs) of the keywords, "deep learning" (AAY:2020.83), "optical coherence tomography angiography" (AAY:2019.59), "intravitreal Aflibercept" (AAY:2019.29), and "dexamethasone implant" (AAY:2019.20) were recognized as the hotspots of the DME research area in the short run.
    CONCLUSION: In the past two decades, the United States was in master status in DME research. Although intravitreal drug injection has been the mainstream therapy for a long time, the effectiveness of different drugs, such as dexamethasone, new solutions for drug delivery, such as intravitreal implantation, and more accurate tools for the classification and follow-up of DME patients, such as deep learning systems, are still research hotspots.
    DOI:  https://doi.org/10.4103/IJO.IJO_399_23
  50. Womens Health (Lond). 2023 Jan-Dec;19:19 17455057231219613
    Gender and research productivity of award recipients among Canadian national ophthalmology and affiliate subspecialty societies.
    Anne Xuan-Lan Nguyen, Golnaz Zahedi-Niaki, Leonardo Lando, Cindy Ml Hutnik, Albert Y Wu.
       BACKGROUND: Although women remain historically underrepresented in medical achievement awards, gender distribution of award recipients in ophthalmology in Canada remain to be explored based on research productivity metrics.
    OBJECTIVE: To characterize the gender distribution of award recipients among the main Canadian national ophthalmological societies and subspecialty affiliates based on research productivity, graduate degrees, affiliated institution, and award type.
    DESIGN: Retrospective, observational study.
    METHODS: Award recipients were selected from the Canadian Ophthalmological Society (COS), Canadian Association of Paediatric Ophthalmology and Strabismus (CAPOS); Canadian Cornea, External Disease, and Refractive Surgery Society (CCEDRSS); Canadian Council of Ophthalmology Residents (CCOR) Research Proposal Award; and Canadian Glaucoma Society (CGS). The recipients' gender was determined by web search for the gender-specific pronoun, profile photograph check, or using Gender-API. Outcomes included gender distribution of recipients per award, society, year, and training level and differences in research productivity.
    RESULTS: Thirteen special awards were given to 255 recipients (215 individuals) from 1995 to 2022. In total, 31% of recipients were women, the majority being from Canada. Women had a significantly lower median h-index (2.0 (0-62) women versus 4.0 (0-81) men, p = 0.001) and number of published documents (3.0 (0-213) women versus 8.0 (0-447) men, p < 0.001). On stratified analyses by type of award (research or lifetime achievement) and level of training (trainee or ophthalmologist), significant differences were found for mean h-index and number of publications for awardees within the research category (p = 0.01 and p = 0.02, respectively) and trainee level (p = 0.01 and p = 0.02, respectively). Overall, women's proportion rates in awards did not reach parity in 27 out of the 28 years analyzed.
    CONCLUSION: Women were confirmed to be historically minored in proportion among the prominent society awards in Canada, with attested research disparity possibly explaining some of this bias. These findings require further confirmation in larger cohorts accounting for additional educational, institutional, and provincial factors.
    REGISTRATION: Not applicable.
    Keywords:  awards; disparity; gender; ophthalmology; recognition
    DOI:  https://doi.org/10.1177/17455057231219613
  51. Mol Neurobiol. 2023 Dec 16.
    Stem Cell Therapy in Neonatal Hypoxic-Ischemic Encephalopathy and Cerebral Palsy: a Bibliometric Analysis and New Strategy.
    Qiu-Xia Xiao, Min-Jian Geng, Yi-Fei Sun, Yu Pi, Liu-Lin Xiong.
      The aim of this study was to identify related scientific outputs and emerging topics of stem cells in neonatal hypoxic-ischemic encephalopathy (NHIE) and cerebral palsy (CP) through bibliometrics and literature review. All relevant publications on stem cell therapy for NHIE and CP were screened from websites and analyzed research trends. VOSviewer and CiteSpace were applied to visualize and quantitatively analyze the published literature to provide objective presentation and prediction. In addition, the clinical trials, published articles, and projects of the National Natural Science Foundation of China associated with stem cell therapy for NHIE and CP were summarized. A total of 294 publications were associated with stem cell therapy for NHIE and CP. Most publications and citations came from the USA and China. Monash University and University Medical Center Utrecht produced the most publications. Pediatric research published the most studies on stem cell therapy for NHIE and CP. Heijnen C and Kavelaars A published the most articles. Cluster analyses show that current research trend is more inclined toward the repair mechanism and clinical translation of stem cell therapy for NHIE and CP. By summarizing various studies of stem cells in NHIE and CP, it is indicated that this research direction is a hot topic at present. Furthermore, organoid transplantation, as an emerging and new therapeutic approach, brings new hope for the treatment of NHIE and CP. This study comprehensively summarized and analyzed the research trend of global stem cell therapy for NHIE and CP. It has shown a marked increase in stem cell therapy for NHIE and CP research. In the future, more efforts will be made on exploring stem cell or organoid therapy for NHIE and CP and more valuable related mechanisms of action to achieve clinical translation as soon as possible.
    Keywords:  Bibliometrics; Cerebral palsy; Neonatal hypoxic-ischemic encephalopathy; Organoid; Stem cells
    DOI:  https://doi.org/10.1007/s12035-023-03848-0
  52. Hum Vaccin Immunother. 2023 Dec 15. 19(3): 2291900
    A bibliometric and knowledge-map study of CAR-T cell-related cytokine release syndrome (CRS) from 2012 to 2023.
    Huimin Li, Qing Huang, Yuan Zhang.
      CAR-T cell therapy has demonstrated efficacy in treating certain hematological malignancies. However, the administration of CAR-T cells is accompanied by the occurrence of adverse events. Among these, cytokine release syndrome (CRS) has garnered significant attention. In this descriptive study, we set the search criteria to retrieve and obtain articles regarding CAR-T cell-related CRS from the Web of Science Core Collection (WoSCC). The bibliometric and knowledge-map analysis of these documents was conducted using Microsoft Excel 2019, GraphPad Prism 8, CtieSpace, and VOSviewer. 6,623 authors from 295 institutions in 49 countries coauthored a total of 1,001 publications. The leading country in this field was the United States. The most productive institution was the University of Pennsylvania. Carl H. June had the most citations, while Daniel W. Lee had the most co-citations. Research hotspots primarily concentrated on the pathogenesis, serum biomarkers, management, and therapeutic drugs of CRS, alongside neurotoxicity. Emerging topics within this discipline encompassed the following: a. Drugs for effective treatment and intervention of CRS; b. Conducting pertinent clinical trials to acquire real-world data; c. Management of toxicity (CRS and neurotoxicity) associated with CAR-T cell therapy; d. The study of BCMA-CAR-T cells in multiple myeloma (MM); e. Optimizing the CAR framework structure to enhance the effectiveness and safety of CAR-T cells. A bibliometric and scientific knowledge-map analysis provided a unique and objective perspective for exploring the field of CAR-T cell-related CRS, and may provide some new clues and valuable references for researchers.
    Keywords:  CAR-T cells; CRS; bibliometric; emerging trends; research hotspots
    DOI:  https://doi.org/10.1080/21645515.2023.2291900
  53. Environ Res. 2023 Dec 15. pii: S0013-9351(23)02721-4. [Epub ahead of print]244 117917
    Trends on adsorption of lead (Pb) using water hyacinth: Bibliometric evaluation of Scopus database.
    Heri Septya Kusuma, Risma Atiqotun Nida, Vera Listiawati, Destyana Eky Rahayu, Luke Arinda Febryola, Handoko Darmokoesoemo, Andrew Nosakhare Amenaghawon.
      Heavy metals (Cd, Ni, Zn, Cu, Cr, and Pb) are widely recognized as being hazardous to human health and environmentally deleterious. Therefore water hyacinth is used as a greener adsorption material. This study is a bibliometric analysis of research developments on the adsorption of lead (Pb) using water hyacinth (1995-2023). The data was retrieved from the Scopus database and analyzed using VOSviewer software to determine the relationship between keywords from each published document. The results of this research was divided into three parts: 1) publication output, 2) global research, and 3) keyword research. From the data obtained, it was found that there has been an increasing research trend of adsorption of lead using water hyacinth, although it is not significant and fluctuating. Overall, this study can be used by researchers to quantitatively assess trends and future directions of this research topic.
    Keywords:  Adsorption; Lead; Scopus database; VOSviewer; Water hyacinth
    DOI:  https://doi.org/10.1016/j.envres.2023.117917
  54. Cureus. 2023 Nov;15(11): e48891
    Rats in Epilepsy Research: A Bibliometric Analysis of Citations Between 1969 and 2020 on Experimental Models in Epilepsy.
    Carmen Rubio, Fernando Gatica, Alonso Portila, David Vázquez, José Molina-García, Ernesto Piñón, Moisés Rubio-Osornio.
      Epilepsy stands as a prominent neurological disorder, affecting a substantial number of individuals who, unfortunately, do not respond to conventional antiepileptic medications. To unravel the intricate mechanisms underlying epileptic seizures and explore potential therapeutic avenues, researchers have turned to animal models. Among these models, rats have emerged as one of the cornerstones of epilepsy research. This bibliometric analysis embarks on the crucial task of delving into the role of rat models in deciphering the mysteries of epileptic seizures and, notably, pinpointing the most prevalent models in use. Our study harnessed Scopus' citation tracking feature to review a range of research papers dating from 1969 to 2020, all dedicated to the exploration of epileptic seizures in rats. The citations that emerged from this rigorous process were subjected to thematic coding, primarily centered around the specific epileptic animal models employed, and subsequently, comprehensive descriptive statistics were computed. In this effort, we found a total of 1,318 publications that explore the world of rat studies, accumulating a substantial citation count of 44,824 references. This analysis illuminated the invaluable role that research employing rat models has played in shaping our current clinical understanding of epileptic seizures. Notably, several models have emerged as predominant forces in this field, including those induced by pilocarpine, pentylenetetrazole (PTZ), kainic acid (KA), electric kindling, and electroshock. This bibliometric exploration serves as a resounding reminder of the pivotal position that rat models occupy in advancing our comprehension of epilepsy. These findings resonate strongly, underscoring the continued importance of directing research and development funding toward this debilitating disorder, with the ultimate aim of maximizing the benefits for the patients grappling with this condition. The potential to revolutionize our approach to epilepsy and enhance the quality of life for those affected remains a beacon of hope, illuminated by the contributions of these tireless researchers and their trusty rat companions.
    Keywords:  bibliometric analysis; epilepsy; experimental model; rat; seizure
    DOI:  https://doi.org/10.7759/cureus.48891
  55. Sci Rep. 2023 Dec 15. 13(1): 22348
    Knowledge mapping of vocational education and training research (2004-2020): a visual analysis based on CiteSpace.
    Yumi Tian, Jiayun Liu, Xin Xu, Xueshi Wu.
      The study aims to analyze the leading researchers of vocational education and training from dimensions of individuals, institutions and countries. This article utilises the scientific information measurement software-CiteSpace-to conduct a scientometric analysis of 2,024 articles on vocational education and training from the Web of Science (W.o.S.). According to the research results, some useful conclusions can be drawn as follows: (1) vocational education and training research has become interdisciplinary and subject involved are "psychology", "sociology", "economics" and "pedagogy"; (2) the United States, the Netherlands and Australia make the majority of contributions and there are numerous collaborations among countries; (3) Univ Amsterdam, Univ Utrecht and Univ Melbourne were the main research institutions; (4) J Vocat Educ Train, Rev Educ Res, Thesis Elev, Econ Educ Rev and J Educ Work were the top 5 highly cited journals; (5) "Engagement", "Program", "Self-efficacy", "High school", "Predictor" and "Labor market" have become major research hotspots currently.
    DOI:  https://doi.org/10.1038/s41598-023-49636-7
  56. J Sex Med. 2023 Dec 20. pii: qdad152. [Epub ahead of print]
    Gender disparities among publications within international sexual medicine urology journals and the impact of blinding in the review process.
    Madeleine L Burg, Priya Kohli, Nhi Ha, Richard Mora, Trisha Kurup, Hannah Sidhu, Jack Rodman, Giovanni E Cacciamani, Mary K Samplaski.
       BACKGROUND: While female urologists are known to publish at less frequency than their male peers, The Journal of Sexual Medicine was reported to have among the highest growth in female authorship from 2002 to 2020 in urology journals.
    AIM: We sought to assess the frequency of female authorship in sexual medicine journals worldwide and the factors that affect this, including the blinded/unblinded review process.
    METHODS: Eleven sexual medicine journals were assessed for geographic location, peer review method, and SCImago Journal Rank citation index (a metric of citation frequency and prestige). Journals were grouped into top, middle, and bottom quartiles based on metric score. Web of Science was used to access the publications' first, second, last, and corresponding authors from the past 5 years. An internet search or Gender-API.com was used to determine the gender identities of authors. Univariate and multivariable logistic regression models were performed.
    OUTCOMES: Outcomes included the likelihood of female authorship (first, second, last, and corresponding) based on journal location and ranking, the clustering of female authors, the journal's peer review process, and the frequency of female editorial board members.
    RESULTS: Overall, 8938 publications were identified. Women represented 30.7%, 31.3%, 21.3%, and 18.7% of the first, second, last, and corresponding authors, respectively; gender was unable to be assessed for 2.6%, 17.2%, 7.3%, and 2.7%. On univariate analysis, journals from North America, in the top quartile, and with a double-blind review process were more likely to have female authors (P < .001). On multivariate analysis, articles were more likely to have a female first author if they had a double-blind peer review process (odds ratio [OR], 1.20; 95% CI, 1.02-1.40), a female second author (OR, 2.54; 95% CI, 2.26-2.85), or a female corresponding author (OR, 7.80; 95% CI, 6.69-9.10).
    CLINICAL IMPLICATIONS: Gender-concordant mentoring and universal double-blind manuscript review processes may minimize the impact of gender bias and increase female authorship rates, in turn producing more diverse research.
    STRENGTHS AND LIMITATIONS: This is the first study assessing female authorship in sexual medicine journals. Limitations include not assessing every author listed on articles and being unable to determine gender identities for some authors.
    CONCLUSION: Female authorship rates are higher than reported rates of practicing female urologists but still lower than their male peers. Female authors were more likely to be published in journals with double-blind peer review processes and when publishing with additional female authors.
    Keywords:  female authorship; publications; sexual medicine; urology
    DOI:  https://doi.org/10.1093/jsxmed/qdad152
  57. J Surg Educ. 2023 Dec 16. pii: S1931-7204(23)00379-3. [Epub ahead of print]
    Impact of Integrated Vascular Surgery Residency Training Pathway and Professional Development Time on Career Choice and Research Productivity.
    Arash Fereydooni, Andrea T Fisher, Danielle M Mullis, Brigitte K Smith, Michael D Sgroi.
       OBJECTIVE: The limited availability of academic surgery positions has led to increased competition for these jobs. Integrated vascular surgery residency (IVSR) allows for earlier specialization, with some programs providing professional development time (PDT). We hypothesized that IVSR and PDT lead to academic employment and increased research productivity.
    DESIGN: This is a retrospective study of vascular surgery fellowship (VSF) and IVSR graduates.
    SETTING: Training, number of publications, H-index, NIH funding, and employment history were collected using institutional websites, Doximity, Scopus, PubMed, and NIH Research Portfolio Reporting.
    PARTICIPANTS: After a review of the research protocol, the Association of Program Directors in Vascular Surgery (APDVS) provided a list of vascular surgery fellowship (VSF) and IVSR graduates.
    METHODS: After review of the research protocol, the Association of Program Directors in Vascular Surgery (APDVS) provided a list of vascular surgery fellowship (VSF) and IVSR graduates. Training, number of publications, H-index, NIH funding, and employment history were collected using institutional websites, Doximity, Scopus, PubMed, and NIH Research Portfolio Reporting.
    RESULTS: From 2013-2017, comparison of IVSR (n=131) to VSF (n=603) graduates showed that IVSR graduates were more likely to be women (38.17% vs 28.19%; p = 0.024), be MD graduates (99.24% vs 93.37%; p = 0.008), attended programs in the northeast (41.98% vs 27.5%; p < 0.001), have advanced degrees (13.74% vs 6.97%; p = 0.01) and graduate from larger programs (median 15 vs 14 faculty; p = 0.013). There was no significant difference in number of publications per trainee by the end of training (median 4 vs 3; P=0.61) or annual trend in average number of publications. After training, there was no significant difference in the type of practice, academic affiliation, practice region, publication number, H-index, NIH funding, level of academic appointment, or leadership positions. From 2013-2019, a comparison of IVSR graduates with (n=32) and without PDT (n=190) demonstrated that those with PDT were more likely to be women (53.13% vs 34.74%; p = 0.038), have advanced degrees (28.12% vs 8.95%; p = 0.002), be at larger programs (median 14 vs 9 faculty; p < 0.001), train at a top 10 NIH funded program (65.62% vs 21.58%; p < 0.001) and publish more by the end of IVSR (median 9 vs 3; p < 0.001). Graduates with PDT were more likely to have academic employment and affiliation, a higher yearly publication rate, and greater H-index.
    CONCLUSION: IVSR and VSF graduates have comparable academic employment and research productivity. However, PDT during IVSR correlates with an eventual academic career and greater research productivity. This study supports the importance of PDT in developing academic vascular surgeons. It remains necessary to continue both IVSR and VSF training paradigms as healthcare needs of the population are met through both academic and non-academic surgeons.
    Keywords:  Vascular surgery fellowship; academic employment; integrated vascular surgery residency; professional development time; research productivity
    DOI:  https://doi.org/10.1016/j.jsurg.2023.10.009
  58. J Arthroplasty. 2023 Dec 20. pii: S0883-5403(23)01246-9. [Epub ahead of print]
    Methodological Assessment of the 100 Most Cited Articles in Total Knee Arthroplasty in the Last Decade Compared to the All-Time list.
    Jeremy Dubin, Daniel Hameed, Mallory C Moore, Sandeep S Bains, Saarang Patel, James Nace, Michael Mont, Ronald E Delanoism.
       INTRODUCTION: Recent advances in total knee arthroplasty (TKA) have been driven by a growing focus on evidence-based medicine. This transition is reflected in the critical appraisal of both, the quality of work as well as the potential impact on the orthopaedic community. The purpose of our study was to: (1) identify the top 100 most-cited articles in TKA in the last decade and from all-time and (2) compare methodological rigor of the most-cited articles in TKA in the last decade to articles all-time by level of evidence (LOE).
    METHODS: The top 100 cited articles were recorded for manuscripts from the last decade, January 1, 2012 to December 31, 2022 and manuscripts from all-time for TKA. We collected authors, year of publications, journal of the article, country of origin of authors, article type (basic science article, clinical research article), level of evidence (LOE), methodological index for non-randomized studies (MINORS) score, physiotherapy evidence database (PEDro) scale, and citation density (total citations/years published).
    RESULTS: The largest number of studies for all-time TKA (53.0%) and decade TKA (42.0%) were Level III. The average MINORS score for comparative studies was 18.7 for all-time TKA and 20.7 for decade TKA (P<0.001). The average PEDro score was 6.1 for all-time TKA and 8.1 for decade TKA (P>0.05). The highest citation density for all-time TKA was 111 and for past decade was 63. The number of level II studies in TKA increased from 19.0% from all time to 38.0% from the last decade (P<0.05).
    CONCLUSION: Our findings of improved methodologies over time reflect positive steps towards evidence-based practice in TKA. A continued focus on producing methodologically sound studies may guide evidence-based clinical decision-making.
    DOI:  https://doi.org/10.1016/j.arth.2023.12.030
  59. Med Sci Monit. 2023 Dec 19. 29 e941670
    Exploring the Research Landscape of High Myopia: Trends, Contributors, and Key Areas of Focus.
    Kaiyao Chi, Biao Li, Hui Huang, Jianhao Sun, Yanlin Zheng, Lei Zhao.
      BACKGROUND Myopia results when light rays focus before reaching the retina, causing blurred vision. High myopia (HM), defined by a refractive error of ≤-6 diopters (D) or an axial length of ≥26 mm, is an extreme form of this condition. The progression from HM to pathological myopia (PM) is marked by extensive ocular axis elongation. The rise in myopia has escalated concerns for HM due to its potential progression to pathological myopia. The covert progression of HM calls for thorough analysis of its current research landscape. MATERIAL AND METHODS HM-related publications from 2003-2022 were retrieved from the Web of Science database. Using VOSviewer and Citespace software, we conducted a bibliometric and visualized analysis to create document co-citation network maps. These maps detailed authors, institutions, countries, key terms, and significant literature. RESULTS From 9,079 articles, 8,241 were reviewed. An increasing trend in publications was observed, with Kyoko Ohno-Matsui identified as a top contributor. The Journal of Cataract and Refractive Surgery was the primary publication outlet. Chinese researchers and institutions were notably active. The document citation network identified five focal areas: refractive surgery, clinical manifestations/treatment, prevention/control, genetics, and open angle glaucoma. CONCLUSIONS Research emphasis in HM has shifted from refractive surgery for visual acuity enhancement to the diagnosis, classification, prevention, and control of HM complications. Proposals for early myopia intervention to prevent HM are gaining attention. Genetics and HM's link with open angle glaucoma, though smaller in focus, significantly enhance our understanding of HM.
    DOI:  https://doi.org/10.12659/MSM.941670
  60. BMJ Glob Health. 2023 Dec 16. pii: e013316. [Epub ahead of print]8(12):
    Authorship inequalities in global health research: the IeDEA Southern Africa collaboration.
    Veronika W Skrivankova, Stefanie Hossmann, Morna Cornell, Marie Ballif, Carole Dupont, Jacqueline Huwa, Konstantinos Seintaridis, Thokozani Kalua, Gilles Wandeler, Reshma Kassanjee, Andreas D Haas, Karl-Gunter Technau, Lukas Fenner, Nicola Low, Mary-Ann Davies, Matthias Egger.
       BACKGROUND: The International epidemiology Databases to Evaluate AIDS conducts research in several regions, including in Southern Africa. We assessed authorship inequalities for the Southern African region, which is led by South African and Swiss investigators.
    METHODS: We analysed authorships of publications from 2007 to 2020 by gender, country income group, time and citation impact. We used 2020 World Bank categories to define income groups and the relative citation ratio (RCR) to assess citation impact. Authorship parasitism was defined as articles without authors from the countries where the study was conducted. A regression model examined the probability of different authorship positions.
    RESULTS: We included 313 articles. Of the 1064 contributing authors, 547 (51.4%) were women, and 223 (21.0%) were from 32 low-income/lower middle-income countries (LLMICs), 269 (25.3%) were from 13 upper middle-income countries and 572 (53.8%) were from 25 high-income countries (HICs). Most articles (150/157, 95.5%) reporting data from Southern Africa included authors from all participating countries. Women were more likely to be the first author than men (OR 1.74; 95% CI 1.06 to 2.83) but less likely to be last authors (OR 0.63; 95% CI 0.40 to 0.99). Compared with HIC, LLMIC authors were less likely to publish as first (OR 0.21; 95% CI 0.11 to 0.41) or last author (OR 0.20; 95% CI 0.09 to 0.42). The proportion of women and LLMIC first and last authors increased over time. The RCR tended to be higher, indicating greater impact, if first or last authors were from HIC (p=0.06).
    CONCLUSIONS: This analysis of a global health collaboration co-led by South African and Swiss investigators showed little evidence of authorship parasitism. There were stark inequalities in authorship position, with women occupying more first and men more last author positions and researchers from LLMIC being 'stuck in the middle' on the byline. Global health research collaborations should monitor, analyse and address authorship inequalities.
    Keywords:  Health policies and all other topics
    DOI:  https://doi.org/10.1136/bmjgh-2023-013316
  61. Int J Spine Surg. 2023 Dec 12. pii: 8565. [Epub ahead of print]
    Top 25 Most-Cited Articles on Robotic-Assisted Lumbar Spine Surgery.
    Andy Ton, Nicole Hang, William Liu, Ryan Liu, Patrick C Hsieh, Jeffrey C Wang, Raymond J Hah, Ram K Alluri.
       BACKGROUND: Robot-guided lumbar spine surgery has evolved rapidly with evidence to support its utility and feasibility compared with conventional freehand and fluoroscopy-based techniques. The objective of this study was to assess trends among the top 25 most-cited articles pertaining to robotic-guided lumbar spine surgery.
    METHODS: An "advanced document search" using Boolean search operator terms was performed on 16 November 2022 through the Web of Science and SCOPUS citation databases to determine the top 25 most-referenced articles on robotic lumbar spine surgery. The articles were compiled into a directory and hierarchically organized based on the total number of citations.
    RESULTS: Cumulatively, the "Top 25" list for robot-assisted navigation in lumbar spine surgery received 2240 citations, averaging 97.39 citations annually. The number of citations ranged from 221 to 40 for the 25 most-cited articles. The most-cited study, by Kantelhardt et al, received 221 citations, averaging 18 citations per year.
    CONCLUSIONS: As utilization of robot-guided modalities in lumbar spine surgery increases, this review highlights the most impactful studies to support its efficacy and implementation. Practical considerations such as cost-effectiveness, however, need to be better defined through further longitudinal studies that evaluate patient-reported outcomes and cost-utility.
    CLINICAL RELEVANCE: Through an overview of the top 25 most-cited articles, the present review highlights the rising prominence and technical efficacy of robotic-guided systems within lumbar spine surgery, with consideration to pragmatic limitations and need for additional data to facilitate cost-effective applications.
    LEVEL OF EVIDENCE: 5:
    Keywords:  clinical outcomes; lumbar; navigation; pedicle screw; robotic spine surgery
    DOI:  https://doi.org/10.14444/8565
  62. Psychogeriatrics. 2023 Dec 19.
    The prevalence and risk of depression in aged COVID-19 survivors: a bibliometric and meta-analysis.
    Yangguang Lu, Jialing Lou, Bohuai Yu, Yiran Bu, Feitian Ni, Di Lu.
      To explore depression prevalence and related risk factors among elderly coronavirus disease 2019 (COVID-19) survivors, while also evaluating research characteristics. We searched Web of Science, PubMed, Embase, Scopus, CNKI and Wanfang Data for studies that reported COVID-19 and depression in older adults. 'Bibliometrix' facilitated bibliometric analysis and information visualisation. Random-effects models merged depression prevalence and relevant risks. Publication bias and its impact were examined using funnel plots, Begg's test, Egger's linear regression, and trim-and-fill method. Meta-regression, bubble plots, and Baujat plots probed heterogeneity. Sensitivity analysis applied the leave-one-out method. The study is registered with PROSPERO, CRD42023417706. The bibliometric analysis comprised 138 studies. Publication frequency peaked in the US, China, and Italy, reflecting significant growth. The meta-analysis comprised 43 studies. Elderly COVID-19 patients exhibit 28.33% depression prevalence (95% CI: 21.24-35.97). Severe cases (43.91%, 95% CI: 32.28-55.88) experienced higher depression prevalence than mild cases (16.45%, 95% CI: 11.92-21.50). Sex had no depression prevalence impact based on bubble plots. Notably, depression risk did not significantly differ between elderly and young COVID-19 patients (odds ratio (OR) = 1.1808, 95% CI: 0.7323-1.9038). However, COVID-19 infection emerged as a substantial elderly depression risk factor (OR = 1.8521, 95% CI: 1.2877-2.6639). Sensitivity analysis confirmed result robustness. Elderly COVID-19 survivors are likely to develop depression symptoms with regional variations. Severe cases are associated with heightened depression prevalence. COVID-19 infection stands out as a key elderly depression risk factor, while sex does not influence prevalence. The field's expansion necessitates sustained collaboration and extensive research endeavours.
    Keywords:  COVID-19; SARS-Cov-2; aged; bibliometric; depression; meta-analysis
    DOI:  https://doi.org/10.1111/psyg.13057
  63. Environ Sci Pollut Res Int. 2023 Dec 23.
    Analysis of scientific and technological trends in the incorporation of activated carbon in advanced oxidation processes-a bibliometric study.
    Diego Montenegro-Apraez, Fiderman Machuca-Martínez.
      There is high interest in the development of water pollution remediation technologies. Advanced oxidation processes (AOPs) are a promising alternative for the degradation of organic compounds; however, these technologies have been limited mainly by high operating costs and, in some cases, by forming byproducts, which can be more hazardous than the original pollutants. Activated carbon (AC) is a porous material that can be combined with AOP systems in various ways, given its adsorbent and catalytic characteristics. In addition, AC is a flexible, adaptable, and low-cost material. This article presents a bibliometric analysis of AOPs incorporating CA in scientific research and patents; the Scopus database was used to obtain patents and Orbit Express for patents. The most investigated AOPs incorporating AC are photocatalysis processes, Fenton processes, persulfate-based AOP, electrochemical processes, and ozonation. However, it is the persulfate-based AOP that has seen the greatest growth in scientific publications in recent years; this great interest can be related to the synergy that the process has with AC, allowing the degradation of contaminants via radical and non-radical. According to the maturity analysis of scientific publications, photocatalysis, Fenton, electrochemistry, ozonation, and persulfate technologies are in a growth stage and will reach maturity in 2034, 2042, 2040, 2034, and 2035, respectively; these technologies coupled with AC are expected to generate a greater number of patents when they reach maturity.
    Keywords:  Activated carbon; Adsorption; Advanced oxidation processes; Catalyst; Catalyst support; Electrode
    DOI:  https://doi.org/10.1007/s11356-023-31120-4
  64. Food Res Int. 2024 Jan;pii: S0963-9969(23)01219-X. [Epub ahead of print]175 113671
    Insights into the mechanisms and key factors influencing biofilm formation by Aeromonas hydrophila in the food industry: A comprehensive review and bibliometric analysis.
    Md Ashikur Rahman, Shirin Akter, Md Ashrafudoulla, Md Anamul Hasan Chowdhury, A G M Sofi Uddin Mahamud, Si Hong Park, Sang-Do Ha.
      Biofilm formation by Aeromonas hydrophila in the food industry poses significant challenges to food safety and quality. Therefore, this comprehensive review aimed to provide insights into the mechanisms and key factors influencing A. hydrophila biofilm formation. It explores the molecular processes involved in initial attachment, microcolony formation, and biofilm maturation; moreover, it concurrently examines the impact of intrinsic factors, including quorum sensing, cyclic-di-GMP, the efflux pump, and antibiotic resistance, as well as environmental conditions, such as temperature, nutrient availability, and osmotic pressure, on biofilm architecture and resilience. Furthermore, the article highlights the potential of bibliometric analysis as a promising method for conceptualizing the research landscape of and identifying knowledge gaps in A. hydrophila biofilm research. The findings underscore the requirement for focused interventions that prevent biofilm development and raise food sector safety. The consolidation of current information and incorporation of bibliometric analysis enhances existing understanding of A. hydrophila biofilm formation and offers insights for future research and control strategies within a food industry context.
    Keywords:  Aeromonas hydrophila; Bibliometric analysis; Biofilm; Factors; Mechanism
    DOI:  https://doi.org/10.1016/j.foodres.2023.113671
  65. Food Res Int. 2024 Jan;pii: S0963-9969(23)01264-4. [Epub ahead of print]175 113716
    Bibliometric analysis of water kefir and milk kefir in probiotic foods from 2013 to 2022: A critical review of recent applications and prospects.
    Handray Fernandes de Souza, Giovana Felício Monteiro, Lorena Teixeira Bogáz, Eduardo Novais Souza Freire, Karina Nascimento Pereira, Marina Vieira de Carvalho, Adriano Gomes da Cruz, Igor Viana Brandi, Eliana Setsuko Kamimura.
      Although milk kefir and water kefir have different physical, chemical and microbiological characteristics, several microbial species that make up kefir stand out with probiotic functions. Furthermore, because it is suitable for a variety of substrates, kefir and the species of probiotic microorganisms that make it up are seen as a promising alternative in the development of probiotic and health-promoting foods. The aim of this study was to carry out a bibliometric analysis of water kefir and milk kefir in probiotic foods and to critically analyze recent applications and prospects. Using the Scopus database, 202 documents published between 2013 and 2022 were identified and submitted to bibliometric analysis using the VOSviewer software. Regarding recent applications, 107 documents published between 2021 and June 2023 were identified. It was observed that, in the literature consulted, no study used bibliometric analysis to evaluate the use of water kefir and milk kefir in probiotic foods. Due to the presence of probiotic species, kefir has been listed as an alternative for the production of new probiotic food matrices that are beneficial to health. Recent applications show kefir's potential in the development of probiotic products based on fruit and fruit juice, whey beverages, fermented milks and derivatives, and alcoholic beverages such as beers.
    Keywords:  Beverages; Fermentation; Functional foods; Microorganisms
    DOI:  https://doi.org/10.1016/j.foodres.2023.113716
  66. Int J Surg. 2023 Dec 14.
    Comments on 'mapping the landscape of immunonutrition and cancer research: a comprehensive bibliometric analysis on behalf of Nutrionc Research Group'.
    Jiawen Wang, Xinhao Wang, Yaoguang Zhang, Jianye Wang.
      
    DOI:  https://doi.org/10.1097/JS9.0000000000001000
  67. Account Res. 2023 Dec 20. 1-21
    Ten Years later: Assessments of the integrity of publications from one research group with multiple retractions.
    Andrew Grey, Alison Avenell, Mark J Bolland.
      When a research group has multiple retracted publications and/or research misconduct by a member is evident, there is a risk that its other publications are unreliable, so a comprehensive assessment of the group's publications is advisable. We analyzed the comprehensiveness of assessment of the integrity of 300 publications by a research group with numerous retractions and known research misconduct, for 292 of which we raised concerns to publishers and academic institutions between 3/2013 and 2/2020. By 4/2023, 91 (30%) publications had not been assessed by either publisher or academic institution. Publishers had assessed 185 (63%) publications. The 4 academic institutions had assessed 5/36 (14%), 56/216 (26%), 30/50 (60%) and 40/66 (61%) publications. Unprompted assessments, those undertaken without our notification of concerns, occurred for 24 (8%) publications, 3 (1%) by publishers and 21 (7%) by academic institutions. Among 32 journals with ≥2 affected publications, no unprompted assessments of the remaining publication(s) occurred after notification of concerns about the index publication(s). Publishers retracted 58/84 (69%) publications which institutions also assessed and decided needed no editorial action. These analyses demonstrate the failure of publishers and institutions to comprehensively and spontaneously determine the integrity of publications in a setting of known misconduct and multiple retractions.
    Keywords:  Publication integrity; assessment; journals; retraction; universities
    DOI:  https://doi.org/10.1080/08989621.2023.2295996
  68. An Acad Bras Cienc. 2023 ;pii: S0001-37652023000500707. [Epub ahead of print]95(suppl 2): e20230492
    Brazilian South-South Scientific Collaboration and The Sustainable Development Goals.
    Concepta McManus, Abilio Afonso B Neves, Rafael T Schleicher, Henrique Carlos O DE Castro, Felipe Pimentel, Daniel Pimentel, Timothy Joseph Finan.
      We look at Brazilian collaboration in Scientific papers based on SciVal and Incites regarding the Sustainable Development Goals (SDGs) of the United Nations. Data were collected from InCites® and SciVal® (2012-2021). Groups of Global South countries were formed (ASEAN, Asia, Africa, BRICS, Caribbean, Central and Latin America). Analyses included Cluster (Author position, impact/citations, open access, journal quartil), principal component, path and analysis of variance to see the effect of region and SDGs in Brazilian publishing. Scopus data were analysed in Vosviewer® for creating country networks through publication, citation and bibliographic coupling, as well as keyword analysis. SDG 3 (Good Health and Well-Being) dominates all Brazilian scientific collaborations with the various country groups. While gender equality shows greater importance in ASEAN and African countries, Life Below Water (SDG14), on Land (SDG15), and Climate Action (SDG13), are important in all regions. SDGs 1, 8, 10, 12, and 16 show less importance in this collaboration overall. Brazil is relatively more active in Zero Hunger (SDG2) and Life on Land (SDG15) than worldwide. Brazil South-South collaboration in published documents shows higher impact than North South in some areas. Collaboration priorities vary by region and triangulation with countries is high depending on language and region.
    DOI:  https://doi.org/10.1590/0001-3765202320230492
  69. Mar Pollut Bull. 2023 Dec 21. pii: S0025-326X(23)01376-0. [Epub ahead of print]199 115941
    Benthic foraminifera as bioindicators of marine pollution: A bibliometric approach to unravel trends, patterns and perspectives.
    Muhamad Naim Abd Malek, Fabrizio Frontalini.
      Benthic foraminifera, single-celled marine organisms, are known for their wide distribution, high abundance and species diversity, test (i.e., shell) preservation in the sedimentary (e.g., historical) record, and sensitivity to environmental changes. Because of these characteristics, they have been widely used as bioindicators in environmental monitoring and, more recently, as Biological Quality Elements (BQEs) in the Ecological Quality Status (EcoQS) evaluation. The global scientific literature on benthic foraminifera as bioindicators was gathered from the Scopus database (overall 966 papers from 1973 to 2022) and explored with scientometric software. The outcomes highlight that the investigation of benthic foraminiferal response to pollutants started over 50 years ago. Indeed, not only the number of published documents has recently peaked (i.e., 2021 and 2022) but there has been also a growth in the percentages of papers falling within the Decision Sciences category that deals with the application of foraminiferal indices for the EcoQS assessment.
    Keywords:  Biblioshiny; Biomonitoring; Ecology; Scientific literature; Scopus; VOSviewer
    DOI:  https://doi.org/10.1016/j.marpolbul.2023.115941
  70. Environ Sci Pollut Res Int. 2023 Dec 18.
    Bibliometric analysis, physical properties, and experimental evaluation of additives-diesel ternary blends.
    Chandan Kumar, Mukesh Kumar, Umesh Kumar Das, Sumit Sharma.
      The availability of petroleum fuels is being challenged due to high demand and heavy dependence on imports, raising awareness of the need for cleaner alternatives. Urbanization, air quality, economic factors, and emissions limits motivate the search for alternative fuels compatible with compression ignition engines. A comprehensive bibliometric analysis further underscores the escalating worldwide research efforts in this critical domain. According to the existing literature, nitromethane and 2-ethoxy ethyl acetate have demonstrated superior physical and combustion properties compared to other additives. To explore their potential, a meticulous performance and emission analysis was conducted using a single-cylinder, 4-stroke VCR CI engine, employing varying proportions of 2-ethoxy ethyl acetate and a constant 2% blend of nitromethane, with EEA concentrations ranging from 5, 10, to 15% (v/v). This research delved into the influence of these diverse fuel blends on the performance of CI engines and exhaust characteristics within a compression ratio spectrum spanning from 17 to 20. The experimental findings revealed that ternary blends, although having a marginal impact on engine performance, exhibited lower emissions compared to pure diesel. The pinnacle of this investigation emerged with the EEA5NM2D93 blend, which yielded optimal results in terms of both performance and emission characteristics.
    Keywords:  2-Ethoxy ethyl acetate; Diesel; Emissions; Nitromethane; Performance
    DOI:  https://doi.org/10.1007/s11356-023-31490-9
  71. Addict Behav. 2023 Dec 02. pii: S0306-4603(23)00327-1. [Epub ahead of print]151 107932
    Alcohol, cardiovascular disease and industry funding: A co-authorship network analysis of epidemiological studies.
    Jim McCambridge, Su Golder.
       INTRODUCTION: Alcohol's effects on cardiovascular disease (CVD) are controversial. Alcohol industry actors have shown particular interest in this subject, and been extensively involved through research funding, and in other ways, generating concerns about bias, particularly in reviews.
    MATERIAL & METHODS: We conducted a co-authorship network analysis of the primary studies included within a previous co-authorship study of 60 systematic reviews on the impact of alcohol on CVD. Additionally, we examined the relationships between declared alcohol industry funding and network structure.
    RESULTS: There were 713 unique primary studies with 2832 authors published between 1969 and 2019 located within 229 co-authorship subnetworks. There was industry funding across subnetworks and approximately 8% of all papers declared industry funding. The largest subnetwork dominated, comprising 43% of all authors, with sparse evidence of substantial industry funding. The second largest subnetwork contained approximately 4% of all authors, with largely different industry funders involved. Harvard affiliated authors who at the review level formed co-authorship subnetworks with industry funded authors were seen at the primary study level to belong to the largest epidemiological subnetwork. A small number of key authors make extensive alcohol industry funding declarations.
    CONCLUSIONS: There was no straightforward relationship between co-authorship network formation and alcohol industry funding of epidemiological studies on alcohol and CVD. More fine-grained attention to patterns of alcohol industry funding and to key nodes may shed further light on how far industry funding may be responsible for conflicting findings on alcohol and CVD.
    Keywords:  Alcohol; Alcohol Industry; Bias; Cardiovascular disease; Co-authorship network analysis; Conflict of interest
    DOI:  https://doi.org/10.1016/j.addbeh.2023.107932
  72. J Pediatr Orthop. 2023 Dec 19.
    Academic and Demographic Characteristics of Pediatric Orthopaedic Division Chiefs in the United States.
    Joshua D Proal, Noorullah Maqsoodi, Daniele Abela, Emily J Curry, Addisu Mesfin, Xinning Li.
       INTRODUCTION: Division Chiefs (DCs) and department leadership play an integral role within the service. The goal of this study is to assess the demographics and scholarly work of the leadership in pediatric orthopaedics services across the United States and comment on the role of diversity within leadership positions.
    METHODS: Academic medical centers and pediatric hospitals were identified using the Electronic Residency Application Service website, the Pediatric Orthopaedic Society of North America website, and the Children's Hospital Association website. Leadership was identified using the hospitals' respective websites where data such as sex, race/ethnicity, fellowship institution, time since graduating fellowship, and academic rank were collected. Scopus database was used to determine h-indices and PubMed was used to determine the number of publications.
    RESULTS: Of 196 academic centers and 223 pediatric hospitals identified, 98 had a designated DC of the pediatric orthopaedics division. The majority of the DCs were male (85.7%), and leadership positions at hospitals with academic affiliations had a higher proportion of female DCs than nonacademic centers ( P =0.0317). DCs were mostly white (83.7%), followed by Asian (12.2%), and African American (2.0%). The average time since fellowship was 21.1 years and the average h-index was 15.7. The average age of the DCs was 56.8 years old. Of those in academic settings, 48.5% held the rank of professor. The fellowship programs that trained the most DCs were Boston Children's Hospital (16.3%) and Texas Scottish Rite for Children (14.3%).
    DISCUSSION: There is a paucity of available research on leadership characteristics in pediatric orthopaedic surgery. While progress has been made, there is still a lack of diversity that exists among leadership in pediatric orthopaedics, both within the academic setting as well as the private sector. The position of DC is held predominately by white males with a rank of either professor or no academic association. Intentional efforts are needed to continue to increase diversity in leadership positions within pediatric orthopaedic programs in the United States.
    LEVEL OF EVIDENCE: IV.
    DOI:  https://doi.org/10.1097/BPO.0000000000002600
  73. Clin Otolaryngol. 2023 Dec 19.
    Evaluation of the presence of double-organ bias in published randomised controlled dacryocystorhinostomy studies.
    Emine Savran Elibol, Fatih Savran.
       OBJECTIVE: The aim of this study is to show whether journals pay attention to double-organ bias in studies on dacryocystorhinostomy (DCR) treatment. Most statistical tests are based on the assumption that each data entry is independent of the other. However, we wanted to understand whether the eye, which is a double organ in the human body, is a cause of bias and whether sufficient attention has been paid to it in published articles.
    DESIGN: A PubMed search was conducted between November 1997 and November 2021 in the field of ophthalmology and otolaryngology with the terms 'dacryocystorhinostomy' and the limitations of 'people' and 'randomly controlled studies'. Publications containing DCR were searched. The publications published in the 15 journals with the highest impact were selected. The scope of the journal, the scope of the authors, the relevance of the articles, the presence of randomisation, the type of study (drug, endoscopic surgery, laser surgery and external surgery) and the statistical approach to bilateral organ bias were evaluated by two independent observers.
    RESULTS AND MAIN OUTCOME MEASURES: A total of 83 publications were found by Pubmed search. Fifty-six publications were included in the study. Double-organ bias was present in 41% (n = 23) of the cases. Of the 23 biased publications, 46.4% were found to be in the Quartile 1 group. Quartile 4 journals showed bias in only four journals.
    CONCLUSION: Double-organ bias can also be seen in journals with high impact factors and published in recent years. Journals may need to pay more attention to double-organ bias in the publication acceptance process.
    Keywords:  dacryocystorhinostomy; double-organ bias; randomised controlled trial; statistics; two eyes bias
    DOI:  https://doi.org/10.1111/coa.14130
  74. Dent Traumatol. 2023 Dec 20.
    World trends in publication for maxillofacial and dental trauma in the elderly.
    Fabiana Dantas Turino, Lucas Alves Jural, Leticia Lopes A da Silva, Marcela Baraúna Magno, Luciane Cople Maia, Patrícia A Risso.
      Aging may increase the risk of maxillofacial and dentoalveolar trauma (MDT). This review assessed global trends in scientific publications on MDT in the elderly. Six databases were searched. Studies about MDT in the elderly (≥60 years old) were included in two text mining stages (S1 and S2). In S1, all studies with elderly subjects were included, while in S2 only studies in which the elderly were assessed in a separate set of data or in a subanalysis by age groups were included. In S1, relevant data were mined using VantagePoint™ software. In S2, data were descriptively analyzed. There were 2265 studies at S1 and 110 at S2. The publication dates spanned from 1963 to 2023. In S1, the most cited keywords and terms were aged (n = 1872), male (n = 1839), female (n = 1777), "mandible fracture" (n = 460), "orbit fracture" (n = 362), and "maxilla fracture" (n = 118). Thirty authors published 10 or more articles with visible collaboration networks. There was a progressive increase in publications, especially in Europe (n = 150). In S2, most studies were case reports/case series (n = 62). The primary etiology was accidental falls (n = 84), the most affected region was the middle third of the face (n = 65), and dental trauma was rarely reported (n = 15). Cone Beam computed tomography was the most used diagnostic tool (n = 67). Of the 81 articles that addressed therapy, 52 opted for surgical treatment. Although there has been an increase in the number of articles on MDT over the years, studies with the elderly population as a specific study group are still needed. Accidental falls were the most reported etiology, while the middle third of the face and the mandible were the anatomic region and bone most affected, respectively. The high number of case reports indicates the need for improvement in the available scientific evidence about MDT in the elderly.
    Keywords:  dental trauma; elderly; maxillofacial trauma; old people; review
    DOI:  https://doi.org/10.1111/edt.12917
  75. J Nurs Scholarsh. 2023 Dec 20.
    An examination of retracted articles in nursing literature.
    Leslie H Nicoll, Heather Carter-Templeton, Marilyn H Oermann, Hannah E Bailey, Jacqueline K Owens, Jordan Wrigley, Leila S Ledbetter.
       INTRODUCTION: The output of scholarly publications in scientific literature has increased exponentially in recent years. This increase in literature has been accompanied by an increase in retractions. Although some of these may be attributed to publishing errors, many are the result of unsavory research practices. The purposes of this study were to identify the number of retracted articles in nursing and reasons for the retractions, analyze the retraction notices, and determine the length of time for an article in nursing to be retracted.
    DESIGN: This was an exploratory study.
    METHODS: A search of PubMed/MEDLINE, the Cumulative Index to Nursing and Allied Health Literature, and Retraction Watch databases was conducted to identify retracted articles in nursing and their retraction notices.
    RESULTS: Between 1997 and 2022, 123 articles published in the nursing literature were retracted. Ten different reasons for retraction were used to categorize these articles with one-third of the retractions (n = 37, 30.1%) not specifying a reason. Sixty-eight percent (n = 77) were retracted because of an actual or a potential ethical concern: duplicate publication, data issues, plagiarism, authorship issues, and copyright.
    CONCLUSION: Nurses rely on nursing-specific scholarly literature as evidence for clinical decisions. The findings demonstrated that retractions are increasing within published nursing literature. In addition, it was evident that retraction notices do not prevent previously published work from being cited. This study addressed a gap in knowledge about article retractions specific to nursing.
    Keywords:  COPE guidelines; duplicate publication; plagiarism; publishing; research integrity; retraction of publication; scientific misconduct
    DOI:  https://doi.org/10.1111/jnu.12952
  76. An Bras Dermatol. 2023 Dec 18. pii: S0365-0596(23)00258-1. [Epub ahead of print]
    Anais Brasileiros de Dermatologia: adjustments to publication standards for authors. Expansion of Editorial Boards. Considerations about bibliometric analyses.
    Silvio Alencar Marques, Ana Maria Ferreira Roselino, Hiram Laranjeira de Almeida, Lucia Patrícia Fernandes Abbade.
      
    DOI:  https://doi.org/10.1016/j.abd.2023.11.001
  77. Exp Clin Transplant. 2023 Nov;21(11): 893-900
    Current Status and Trends in Lung Transplant Research Funded by the National Natural Science Foundation of China.
    Xianyu Xie, Zijun Zhao, Qinde Wu.
       OBJECTIVES: This study aimed to analyze research projects on lung transplant funded by the National Natural Science Foundation of China from 1986 to 2022 and to provide a scientific reference for lung transplant research.
    MATERIALS AND METHODS: We identified research hotspots and frontiers in the field of lung transplant research using CiteSpace visualization.
    RESULTS: From 1986 to 2022, the National Natural Science Foundation of China funded 93 projects related to lung transplant, with an average of 2.51 projects and ¥0.94 million annually. The National Natural Science Foundation of China funded 30 institutions across 20 provinces, with general and youth science foundation projects comprising 45.16% and 41.93% of the total projects, respectively. The main categories of disciplines included H0113 respiratory intervention, tracheal reconstruction, and lung transplantation; H1105 organ transplantation and transplant immunization; and H0109 acute lung injury and acute respiratory distress syndrome. The research hotspots mainly included ischemia-reperfusion injury, gene regulation, obliterative bronchiolitis, rejection reaction, T cells, and stem cells. The 6 main research clusters were ischemia-reperfusion injury, immune tolerance, obliterative bronchiolitis, stem cells, pulmonary fibrosis, and rejection reaction. The main key word bursts in the past 5 years were "vein endothelial" and "ex vivo lung perfusion."
    CONCLUSIONS: In the past 37 years, National Natural Science Foundation of China-funded projects have significantly advanced the clinical application and basic research of lung transplantation. However, compared with developed countries and other solidorgan transplantations, several problems still require attention and improvements in lung transplant research in China.
    DOI:  https://doi.org/10.6002/ect.2023.0220
  78. Phytomedicine. 2023 Nov 23. pii: S0944-7113(23)00600-1. [Epub ahead of print]123 155241
    Effects of curcumin on non-alcoholic fatty liver disease: A scientific metrogy study.
    Xiankuan Li, Weisan Chen, Jiali Ren, Xinchen Gao, Ying Zhao, Tianbao Song, Kun Fu, Yanchao Zheng, Jinlong Yang.
       BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases encountered in clinical practice. Curcumin can alleviate insulin resistance, inhibit oxidative stress response, reduce inflammation, reduce liver fat deposition, and effectively improve NAFLD through various modalities, inhibiting the progression into cirrhosis and fibrosis.
    PURPOSE: To explore the current status, hot spots, and developing trends of curcumin in NAFLD treatment through quantitative scientific analysis to serve as a reference for subsequent studies.
    STUDY DESIGN: A comprehensive analysis of the mechanism of action of curcumin in the treatment of NAFLD and methods to increase curcumin bioavailability using bibliometric analysis and literature review.
    METHODS: This study used VOSviewer software to analyze the literature related to curcumin treatment of NAFLD in the Web of Science (WOS) core set database. A comprehensive and in-depth review was conducted based on the results of scientific econometric research and literature review.
    RESULTS: The review observed that curcumin can activate various signaling pathways such as AMPK and NF-κB to inhibit oxidative stress and apoptosis, thereby reflecting its pharmacological effects: lowering lipid, anti-inflammatory, reducing insulin resistance, and anti-fibrosis. These mechanisms improve or even reverse the complex pathological features of lipid metabolism disorders associated with NAFLD. Curcumin also can potentially serve as a primary regulatory target for treating hepatic steatosis using gut microbiota. However, these pharmacological effects of curcumin were limited owing to its low bioavailability.
    CONCLUSION: This review discusses NAFLD treatment with curcumin, analyzes the reasons for its low bioavailability, and introduces models for studying and methods for improving curcumin bioavailability. As research on NAFLD grows, future research should capture the trend of basic research, pay attention to clinical research, and continuously explore the therapeutic potential of curcumin.
    Keywords:  A scientific metrology study; Bioavailability; Curcumin; Non-alcoholic fatty liver disease
    DOI:  https://doi.org/10.1016/j.phymed.2023.155241
  79. Arch Dermatol Res. 2023 Dec 16. 316(1): 46
    Trends in Mohs surgery fellowship directors.
    Kayla D Mashoudy, Siri Choragudi, Benjamin Schachner, Zachary Zippi, Isabella Rohrabaugh, Keyvan Nouri.
      The purpose of this study is to illustrate demographic trends among Mohs Micrographic Surgery (MMS) Fellowship Directors. Our search was constructed from the 2022 to 2023 Mohs Micrographic Surgery Fellowship Directory on the Accreditation Council for Graduate Medical Education (ACGME) website. Datapoints gathered included: age, sex, residency/fellowship training location, time since training completion until FD appointment, length in FD role, and personal research H-index. We identified 77 FDs, of which all 77 were included in this study. The mean age was 55.5 years; 55 (71.4%) were men and 20 (26.0%) were women. Most of the FDs who completed the survey did not self-report ethnicity or race, so these measures were not included. The top residency institutions that produced the most FDs were Cleveland Clinic (n = 4), Mayo Clinic (n = 4), New York University Medical Center (NYU, n = 4), and University of California-Los Angeles (UCLA, n = 4); the top fellowship institutions were NYU (n = 7), UCLA (n = 5), Cleveland Clinic (n = 4), and Geisinger Medical Center (n = 4). The mean H-index was 15.9, the mean number of peer-reviewed publications was 71, and the mean time from training completion until FD appointment was 10 years. Our results indicate that a majority of FDs are men (71.4%) and that FDs are more likely to have graduated from certain residency and fellowship programs.
    Keywords:  Dermatologic surgery; Dermatology fellowship; Medical education; Mohs surgery fellowship; Surgical leadership
    DOI:  https://doi.org/10.1007/s00403-023-02786-0
  80. Int Orthop. 2023 Dec 22.
    Unlocking citation obsession and academic identity: the importance of ORCID numbers.
    Philippe Hernigou, Marius M Scarlat.
      
    DOI:  https://doi.org/10.1007/s00264-023-06069-1
  81. Eur J Cardiothorac Surg. 2023 Dec 21. pii: ezad427. [Epub ahead of print]
    Gender representation among speaking and leader roles at European Cardio-thoracic surgical annual meetings.
    Antonella Galeone, Annalisa Bernabei, Julie Cleuziou, Vanessa Menezes, Samina Park, Jolanda Kluin, Cecilia Pompili.
       OBJECTIVE: To evaluate gender representation among session leaders and abstract presenters at European Cardio-thoracic surgical annual meetings.
    METHODS: This is a descriptive study of the gender distribution among session leaders and abstract presenters at 2 European Cardio-thoracic international meetings from 2017 to 2022. Data from publicly available programs were used to generate a list of session leaders and abstract presenters. The primary outcome was to evaluate the proportion of female sessions leaders at annual meetings. Descriptive analyses were performed including Cochran-Armitage trend test for linear trend of proportions.
    RESULTS: A total of 1025 sessions of 11 annual meetings of the EACTS and ESTS were examined. 397 (13,2%) out of 3007 total session leaders and 955 (15,2%) out of 6251 abstract presenters were female. From 2017 to 2022 the proportions of both female session leaders and abstract presenters trended significantly (10,4% to 21,9% (p < 0.001) and 13,7% to 18.3% (p < 0.001), respectively). EACTS female members and female meeting attendance significantly increase from 2017 to 2022 (11,1% to 15,9% (p < 0.001), and 23,7% to 26,9% (p < 0.001), respectively. Most of women attendees at EACTS and ESTS meetings as session leaders and speakers came from Germany, Italy, UK and USA.
    CONCLUSIONS: Women are underrepresented compared to men in leadership and speaking roles at European Cardiothoracic surgical annual meetings. In the last years an encouraging positive trend over time for female leadership roles has been shown and as a result the proportion of female society members is represented at the annual meetings. Related to the genders of attendees at the meetings, there is still a substantial gender gap in leading roles.
    Keywords:  cardio-thoracic surgery meetings; female surgeon
    DOI:  https://doi.org/10.1093/ejcts/ezad427
  82. Nature. 2023 Dec 22.
    Citations show gender bias - and the reasons are surprising.
    Anil Oza.
      
    Keywords:  Publishing; Scientific community; Sociology
    DOI:  https://doi.org/10.1038/d41586-023-03474-9
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