bims-evares Biomed News
on Evaluation of research
Issue of 2023–09–17
fifty-one papers selected by
Thomas Krichel, Open Library Society



  1. J Endod. 2023 Sep 08. pii: S0099-2399(23)00582-4. [Epub ahead of print]
       INTRODUCTION: Knowledge of bibliometric indices on the avulsion of permanent teeth can help researchers to identify gaps in the literature. The aim of this study was to analyze the bibliometric characteristics of the 100 most cited articles on the avulsion of permanent teeth.
    MATERIALS AND METHODS: Two researchers conducted an unfiltered search in the Core Collection section of the Web of Science (WoS-CC) database. The following data were extracted: position in the citation list, total number and density of citations, title, authors, institution, country, year of publication, journal, keywords, study design, tooth storage medium, and other topics of interest. Bibliometric networks were generated and analyzed using the VOSviewer software. Descriptive analysis and a Poisson regression analysis were performed (p < 0.05).
    RESULTS: The number of citations per article varied between 31 and 407. The average was 70.05, and 13 articles received more than 100 citations. JO Andreasen (n=13) and M Trope (n=15) were the authors who contributed most often to publications. The United States was the country with the highest number of articles (n=31). Authors associated with the University of Copenhagen, Denmark (n=9) and University of North Carolina, USA (n=10) showed higher productivity. In vitro/animal model studies were the most frequent study designs (n=50), and the most-discussed topic of interest was prognosis (n=47). There was strong clustering among 13 research groups.
    CONCLUSION: Observational studies, published by authors from Europe and about Prognosis or Treatment presented more citation ratio in WoS-CC. Clinical studies on permanent tooth avulsion are needed to increase the quality of scientific evidence and provide insights for health professionals and public policy makers.
    Keywords:  Bibliometrics; Citation analysis; Tooth Avulsion; Tooth Injuries; Tooth Replantation
    DOI:  https://doi.org/10.1016/j.joen.2023.09.001
  2. Front Oncol. 2023 ;13 1229222
       Background: MBC is a lethal form of breast cancer that arises when cancer cells invade other organs or tissues. The treatment of MBC needs personalized approaches based on the tumor and patient characteristics. The purpose of this paper is to analyze MBC studies from 2002 to 2022 using bibliometrics and to investigate its current situation, main contributors, core journals, highly cited papers, and topic evolution.
    Materials and methods: We retrieved data from Web of Science Core Collection (WOSCC). Bibliometric analysis of the included literatures mainly used the following tools: the function of "analyze results" and "citation report" in WoS, Microsoft excel 2021, CiteSpace v.6.1. R6, VOSviewer v.1.6.18, BICOMB v.2.04 and gCLUTO v.1.0.
    Results: We found 12,653 articles on MBC research published in 1, 802 journals by 69, 753 authors from 118 countries. The annual output and citation of MBC articles showed a rising trend over time. The United States was the most influential country in MBC research. The most cited journal in this field was The Journal of Clinical Oncology. And the most cited article was by Slamon DJ. The co-word analysis of keywords divides MBC into six research clusters. The hormone receptor-positive MBC and liquid biopsy of MBC are the frontiers research trends. "CDK4/6 inhibitor" had the highest burst strength.
    Conclusion: Our bibliometric analysis offers a comprehensive overview of MBC research in the past two decades. It shows the current situation, main contributors, core journals, highly cited papers, and topic evolution of this field. Our study can assist researchers and practitioners to comprehend the development and trends of MBC research and to discover potential directions for future research.
    Keywords:  bibliometric analysis; co-word analysis; cocitation analysis; metastatic breast cancer; research trends analysis
    DOI:  https://doi.org/10.3389/fonc.2023.1229222
  3. Am J Transl Res. 2023 ;15(8): 5364-5372
      The number of articles on the relationships between the intestinal microbiota and liver diseases has continued to increase. The aim of this study was to assess publications on this topic, identify research hotspots, and predict trends of future research. Articles on this topic published from 2001 to 2021 were obtained from the Web of Science Core Collection. Bibliometric analysis and visualization were performed to identify research hotspots and trends with the use of the online bibliometric analysis platform, VOSviewer, and CiteSpace. In total, 4415 articles were included for bibliometric analysis. The annual output of research on this topic gradually increased over the past 21 years. China contributed the most publications (1254), while the United States was the core (centrality = 0.35) of the country-cooperation network and Schnabl B published the most articles (n = 80). High-frequency keywords included "gut microbiota", "inflammation", "obesity", "insulin resistance", "disease", "fatty liver disease", "metabolism", and "probiotics". The keywords that have burst in recent years include "intestinal microbiota", "dysbiosis", and "gut-liver axis". The relationships between dysbiosis of the intestinal microbiota and liver diseases, such as nonalcoholic fatty liver disease (NAFLD), cirrhosis, and hepatocellular carcinoma (HCC), are current research hotspots. Treatment for NAFLD, nonalcoholic steatohepatitis, cirrhosis, and HCC via regulation of the intestinal microbiota is predicted as a research hotspot in the following years, especially immunotherapy for HCC. These findings should prove helpful to scholars to direct future research on the relationships between the intestinal microbiota and liver diseases.
    Keywords:  CiteSpace; Intestinal microbiota; VOSviewer; bibliometric analysis; liver diseases
  4. Semin Ophthalmol. 2023 Sep 11. 1-6
       PURPOSE: This review analyzed the top 100 most-cited thyroid eye disease (TED) papers.
    METHODS: In November 2022, Scopus was searched for the most highly cited TED works since inception. For each paper, journal of origin and impact factor, corresponding author country and specialty affiliation, citation count, publication year, database-affirmed study funding, and open-access status were extracted.
    RESULTS: A total of 76 primary and 24 secondary articles were published between 1969 and 2021 across 29 journals, with a median (range) of 186.5 (133-930) citations. The most cited journal was Journal of Clinical Endocrinology and Metabolism (25 articles; 5126 citations). The most cited article was 'Graves' ophthalmopathy' (Bahn 2010; New England Journal of Medicine; 930 citations). Articles hailed from 10 countries, with most from the United States (38 articles; 9194 citations). Endocrinology (n = 59) and ophthalmology (n = 26) were the most common corresponding authors. Nineteen first authors contributed multiple articles. Only journal impact factor was significantly associated with citation count (p = .0002; ρ = 0.45).
    CONCLUSION: A variety of medical disciplines, Western countries, and study personnel contributed to highly cited thyroid eye disease research. Thus, this research area is not exceedingly informed by any singular perspective. Further, it can be interpreted with increased confidence for their generalizability of results to patients globally.
    Keywords:  Citation; Graves’ ophthalmopathy; literature; review; thyroid eye disease
    DOI:  https://doi.org/10.1080/08820538.2023.2256838
  5. Neuroepidemiology. 2023 Sep 12. 1
       INTRODUCTION: Alzheimer's disease (AD) often presents with sleep disorders, which are also an important risk factor for AD, affecting cognitive function to a certain extent. This study aimed to reveal the current global status, present hotspots, and discuss emerging trends of sleep and AD using a bibliometric approach.
    METHODS: Research and review articles related to sleep and AD from 2003 to 2022 were extracted from the Web of Science Core Collection. VOSviewer 1.6.18.0, Scimago Graphica, and CiteSpace 6.2.R2 were used to map the productive and highly cited countries, institutions, journals, authors, references, and keywords in the field.
    RESULTS: Overall, 4,008 publications were included in this bibliometric analysis. The number of publications and citations showed an increasing trend over the past two decades. The USA and China had the largest and second largest, respectively, number of publications and citations and cooperated with other countries more closely. Ancoli-Israel Sonia published the most papers, and Holtzman David M was co-cited most frequently. The most productive journal was Journal of Alzheimer's Disease, and Neurology was the most frequently cited journal. The risk factors, β-amyloid, tau, neuroinflammation, astrocytes, glymphatic system, orexin, functional connectivity, and management have been the main research directions of researchers over the past few years and may be the future trend of valuable research.
    CONCLUSION: We identified hotspots and emerging trends including risk factors, Aβ, tau, neuroinflammation, the glymphatic system, orexin, and management, which may help identify new therapeutic targets and improve clinical efficacy of sleep and AD.
    DOI:  https://doi.org/10.1159/000533700
  6. Fundam Clin Pharmacol. 2023 Sep 12. e12956
       BACKGROUND: Astragaloside IV has emerged as a pharmaceutical monomer with great medical applications and potential. Astragaloside IV has many effects such as improving myocardial ischemia, cerebral ischemia-reperfusion injury, anti-inflammatory, analgesic, antiviral, promoting lymphocyte proliferation, and antitumor effects. However, there are few bibliometric studies on astragaloside IV.
    OBJECTIVES: We aim to visualize the hotspots and trends in astragaloside IV research through bibliometric analysis to further understand the future development of basic and clinical research. Methods The articles and reviews on astragaloside IV were screened from the Web of Science Core Collection, and knowledge maps were generated using CiteSpace software. Bibliometric analysis was performed on 971 articles published from 1998 to 2022.
    RESULTS: The number of articles on astragaloside IV increased yearly. These publications came from 42 countries/regions, with China being the largest. The primary research institutions were Shanghai University of Traditional Chinese Medicine and Guangzhou University of Traditional Chinese Medicine. Journal of Ethnopharmacology was the most studied journal and co-cited journal. A total of 473 authors were included, among which Hongxin Wang had the highest number of publications and Zhang Wd had the highest total citation frequency. After analysis, the most common keywords are astragaloside IV, expression, and oxidative stress. Cardiovascular disease, cerebral ischemia, cancer, and kidney disease are current and developing research fields.
    CONCLUSION: This study used bibliometrics and visualization methods to analyze the research hotspots and trends of astragaloside IV. Astragaloside IV on ischemia-reperfusion injury, cancer, and tumor may become the focus of future research.
    Keywords:  Astragaloside IV; CiteSpace; Leguminosae; bibliometrics
    DOI:  https://doi.org/10.1111/fcp.12956
  7. Front Mol Neurosci. 2023 ;16 1148179
       Objective: To explore the development context, research hotspots and frontiers in the glymphatic system (GS) field from 2012 to 2022 by bibliometric analysis.
    Methods: The Web of Science Core Collection (WoSCC) database was searched for articles published between 2012 and 2022. Microsoft Excel was used to manage the data. VOSviewer, CiteSpace, GraphPad Prism, the Web of Science, and an online analysis platform for bibliometrics (http://bibliometric.com/) were used to analyze the countries, institutions, journals, and collaboration networks among authors and the types of articles, developmental directions, references, and top keywords of published articles.
    Results: A total of 412 articles were retrieved, including 39 countries/regions, 223 research institutes and 171 academic journals. The subject classifications related to the GS were Neuroscience, Clinical Neuroscience and Radiology/Nuclear Medicine/Medical Imaging. The United States has maintained its dominant and most influential position in GS research. Among research institutions and journals, the Univ Rochester and Journal of Cerebral Blood Flow and Metabolism had the highest number of academic articles, respectively. Nedergaard M had the most published article, and Iliff JJ had the most co-citations. The top two keywords with the highest frequency were "glymphatic system" and "cerebrospinal fluid."
    Conclusion: This research provides valuable information for the study of the GS. The bibliometric analysis of this area will encourage potential collaborations among researchers, defining its frontiers and directions for development.
    Keywords:  CiteSpace; VOSviewer; WoSCC; bibliometrics; glymphatic system; visualization
    DOI:  https://doi.org/10.3389/fnmol.2023.1148179
  8. Radiat Oncol. 2023 Sep 13. 18(1): 151
       BACKGROUND: In patients with nasopharyngeal cancer (NPC), radiation-induced temporal lobe injury (TLI) is the most dreaded late-stage complication following radiation therapy (RT). We currently lack a definitive algorithmic administration for this entity. In the meantime, the pathogenesis of TLI and the mechanism-based interventions to prevent or treat this adverse effect remain unknown. To better answer the aforementioned questions, it is necessary to comprehend the intellectual foundations and prospective trends of this field through bibliometric analysis.
    METHODS: Articles were gathered from the Web of Science Core Collection (WoSCC) database between 2000 and 2022. CiteSpace was utilized to create a country/institutional co-authorship network, perform dual-map analysis, and find keywords with citation bursts. VOSviewer was used to build networks based on author co-authorship, journal citation, co-citation analysis of authors, references, and journals, and keyword co-occurrence.
    RESULTS: A total of 140 articles and reviews were included in the final analysis. The number of publications has steadily increased with some fluctuations over the years. The country and institution contributing most to this field are the China and Sun Yat-Sen University. Han Fei was the most prolific author, while Lee Awm was the most frequently cited. The analysis of co-occurrence revealed three clusters, including: "radiation-induced injury or necrosis in NPC," "clinical studies on chemotherapy/radiotherapy complications and survival in recurrent NPC," and "IMRT/chemotherapy outcomes and toxicities in head and neck cancer"). Most recent keyword bursts were "volume," "temporal lobe injury," "toxicities," "model," "survival," "intensity modulated radiotherapy," "induced brain injury," "head and neck cancer," and "temporal lobe."
    CONCLUSION: This study provides some insights of the major areas of interest in the field of radiation-induced TLI in patients with NPC by bibliometric analyses. This study assists scholars in locating collaborators and significant literature in this field, provides guidance for publishing journals, and identifies research hotspots. This analysis acknowledges significant contributions to the discipline and encourages the scientific community to conduct additional research.
    Keywords:  Bibliometric analysis; Nasopharyngeal carcinoma; Radiation induced complication; Temporal lobe injury
    DOI:  https://doi.org/10.1186/s13014-023-02345-x
  9. Ann Card Anaesth. 2023 Apr-Jun;26(2):26(2): 197-203
       Objective: To identify the worldwide bibliometric characteristics of research on SARS-CoV-2 infection and cerebrovascular disease.
    Methods: A retrospective, descriptive, and bibliometric study was performed. We analyzed 1834 publications about COVID-19 and cerebrovascular disease from the Scopus database considering the time since the beginning of the pandemic between 2019 and 2020. Bibliometric indicators were evaluated such as number of citations, citations per publication by authors, countries, journals, and collaborations at national, international, institutional, and impact levels according to Cite Score Quartile and h-index metrics. All analysis was performed using SciVal software.
    Results: The highest percentage of articles corresponded to universities in the United States, including Harvard and New York with 59 and 20 publications, respectively, and the University of Toronto in Canada with 22 publications. In relation to citation indicators, journals such as Stroke and Journal Stroke and Cerebrovascular diseases obtained 1971 and 561 citations, respectively. Regarding collaboration indicators, the national collaboration index was 39.4% and the institutional collaboration index was 31.1%. Finally, neurology, cardiovascular medicine, and cardiology and surgery were the subject areas with the highest research results, with 424, 217, and 128 studies, respectively.
    Conclusion: It was observed that the United States was the country with the highest scientific production on COVID-19 and cerebrovascular disease in the year 2020 in the different health areas; however, more research is still needed worldwide for a better analysis of the bibliometric indicators on the subject.
    Keywords:  Bibliometric; COVID-19; cerebrovascular disease; scopus
    DOI:  https://doi.org/10.4103/aca.aca_70_22
  10. World Neurosurg. 2023 Sep 12. pii: S1878-8750(23)01293-7. [Epub ahead of print]
       OBJECTIVE: To analyze the current research trends and potential mechanisms related to the role of autophagy in intervertebral disc degeneration (IVDD) and to provide new ideas for future research in this field.
    METHODS: All publications on IVDD and autophagy were retrieved and extracted from the Web of Science (WOS) core collection database. The results were evaluated and visualized using the bibliometric website, Citespace and VOSviewer software, including annual publications, countries, institutions, authors, journals, research areas, funding agencies, citations and keywords.
    RESULTS: From January 1, 2011 to December 31, 2022, a total of 323 reviews and original articles were included, and the overall trend in the number of publications was growing rapidly. China and the United States were the countries with the most scientific research achievements in the world. The 323 publications got a total number citations of 6949, with an H-index of 43 and an average citations of 21.51. The top publication countries, institutions, authors, journals, research areas and funding agencies were China, Huazhong University of Science and Technology, Tongji Medical College Cao Yang, Oxidative Medicine and Cellular Longevity, cell biology, National Natural Science Foundation of China, respectively. Most of the keywords were associated with the mechanisms and regulatory networks of autophagy. In addition, with increasing evidence demonstrated the key role of autophagy in IVDD, therapy, signaling pathway, and mitophagy are emerging as new research hotspots that should be paid more attention to.
    CONCLUSIONS: This study provided a scientific perspective on autophagy in IVDD and elucidated the current research status and hotspots in this field. The mechanism of autophagy and the application of regulating autophagy in the treatment of IVDD deserve further research.
    Keywords:  Autophagy; IVDD; VOSviewer; bibliometric analysis; citespace; intervertebral disc degeneration
    DOI:  https://doi.org/10.1016/j.wneu.2023.09.024
  11. J Am Podiatr Med Assoc. 2023 Jul-Aug;113(4):pii: 21-077. [Epub ahead of print]113(4):
       BACKGROUND: Bibliometric studies in the field of orthopedics have increased because of the large volume of the available literature that prevents understanding the general status of the related field. This study aimed to identify and analyze the 100 most-cited articles related to flatfoot to reveal their characteristics and research trends.
    METHODS: Available literature on the Web of Science database until the end of 2020 were analyzed, and the 100 most-cited articles were determined. The characteristics of articles including publication year, authors, institutions, country, journal, number of pages, number of references, study design, level of evidence, main topic, age group, the specialty of the first author, and availability of funding were extracted and statistically analyzed for any association with the number of citations or citation density.
    RESULTS: The average citation number was 63.1 ± 43.8 (range, 30-278). The average citation density was 3.4 ± 1.8 (range, 0.8-12.6). The United States was the leading country with 65 articles, followed by Taiwan and the United Kingdom with five articles from each. Twenty-six papers had Level III evidence and 36 papers had Level IV evidence. Only three studies had Level I evidence and three had Level II evidence. The majority of articles (43 papers) were published in Foot & Ankle International. Citation density was positively correlated with publication year (P < .001) and the number of references (P = .004).
    CONCLUSIONS: The available data provide general characteristics of the 100 most influential papers about flatfoot. The vast majority of papers had a low level of evidence, indicating the need for higher quality research.
    DOI:  https://doi.org/10.7547/21-077
  12. World Neurosurg. 2023 Sep 13. pii: S1878-8750(23)01292-5. [Epub ahead of print]
       BACKGROUND: Spinal cord injury (SCI) is a devastating condition, often leading to significant disability and impairment. As crucial immune cells, macrophages play a critical role in the pathophysiology of SCI. Understanding the current state of knowledge and research trends related to macrophages in SCI is crucial for developing effective therapeutic interventions.
    METHODS: Using search strategies, we retrieved relevant articles from the Web of Science Core Collection (WOSCC), resulting in a robust dataset for analysis. VOSviewer, Citespace, and PRISM were employed for analysis and visualization. Various bibliometric indicators, including publication trends, citation analysis, co-authorship networks, and keyword analysis, were utilized to assess the scholarly landscape of macrophage research in SCI.
    RESULTS: Our findings revealed a steady increase in publications over past 33 years, indicating a growing interest in this field. We identified Popovich Phillip G was the most influential author, Ohio State University was the most influential institution, Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord was the most influential paper in this field.
    CONCLUSION: This bibliometric analysis provides a comprehensive overview of the current knowledge landscape and research trends regarding macrophages in SCI. Neuroinflammatin and macrophage polarization, transplation and molecular mechanism were emerging research areas and novel directions. Our study serves as a valuable resource for researchers in spinal cord injury research and therapeutic development.
    Keywords:  Bibliometric Analysis; Macrophage; Microglia; Neuroinflammation; Spinal cord injury
    DOI:  https://doi.org/10.1016/j.wneu.2023.09.022
  13. World J Psychiatry. 2023 Aug 19. 13(8): 593-606
       BACKGROUND: Depression is one of the most common and important psychological issues faced by dialysis patients. It can make it more difficult for them to adhere to their treatment regimen, which, in turn, can worsen their physical symptoms and lead to poorer health outcomes.
    AIM: To examine the evolution and growth of publications related to dialysis and depression. The objectives were to identify the number of publications, the top active countries, the contributed institutions, funding agencies and journals, as well as to perform citation and research theme analysis.
    METHODS: The search was conducted using the Scopus database for publications related to dialysis and depression between 1970 and 2022. Subsequently, bibliometric analysis was carried out on the data obtained using VOSviewer software, version 1.6.9. This analysis included visualization analysis, co-occurrence analysis and examination of publication trends in dialysis and depression.
    RESULTS: We identified 800 publications that met the search criteria. The number of publications related to dialysis and depression has increased significantly in the past two decades. The USA led the way with 144 publications, which is 18% of all publications on this topic. Turkey came second with 88 publications (11%), followed by China with 55 publications (6.88%) and Iran with 52 publications (6.5%). Analysis of the research theme identified three main clusters related to gender differences in prevalence, identification of depression as a risk factor, and effective interventions to relieve depression. Future research direction analysis shows a shift toward effective interventions to relieve depression in dialysis patients.
    CONCLUSION: This study provides a comprehensive overview of growth, trends and research themes related to dialysis and depression that could help researchers identify gaps in the literature and develop future research.
    Keywords:  Bibliometric; Depression; Dialysis; Hot issues; Scopus
    DOI:  https://doi.org/10.5498/wjp.v13.i8.593
  14. J Pain Res. 2023 ;16 3045-3060
       Purpose: Low back pain (LBP) is a prevalent musculoskeletal disorder, and manual therapy (MT) is frequently employed as a non-pharmacological treatment for LBP. This study aims to explore the research hotspots and trends in MT for LBP. MT has gained widespread acceptance in clinical practice due to its proven safety and effectiveness. The study aims to analyze the developments in the field of MT for LBP over the past 23 years, including leading countries, institutions, authoritative authors, journals, keywords, and references. It endeavors to provide a comprehensive summary of the existing research foundation and to analyze the current cutting-edge research trends.
    Methods: Relevant articles between 2000 and 2023 were retrieved from the Web of Science Core Collection (WOSCC) database. We used the software VOSviewer and CiteSpace to perform the analysis and summarize current research hotspots and emerging trends.
    Results: Through screening, we included 1643 papers from 2000 to 2023. In general, the number of articles published each year showed an upward trend. The United States had the highest number of publications and citations. Canadian Memorial Chiropractic College was the most published research institution. The University of Pittsburgh in the United States had the most collaboration with other research institutions. Long, Cynthia R. was the active author. Journal of Manipulative and Physiological Therapeutics was the most prolific journal with 234 publications.
    Conclusion: This study provides an overview of the current status and trends of clinical studies on MT for LBP in the past 23 years using the visualization software, which may help researchers identify potential collaborators and collaborating institutions, hot topics, and new perspectives in research frontiers, while providing new clinical practice ideas for the treatment of LBP.
    Keywords:  CiteSpace; VOSviewer; back pain; bibliometric analysis; manual therapy
    DOI:  https://doi.org/10.2147/JPR.S418458
  15. Transl Cancer Res. 2023 Aug 31. 12(8): 1891-1894
      
    Keywords:  Apoptosis resistance; bibliometrics analysis; chronic inflammation; nasopharyngeal carcinoma (NPC)
    DOI:  https://doi.org/10.21037/tcr-23-897
  16. Front Nutr. 2023 ;10 1253255
      The evolution of research literature on monk fruit extract and mogroside as sweeteners has yet to be investigated. No study has evaluated this literature from a bibliometric perspective. This bibliometric study analyzed the relevant research literature indexed in Web of Science, to unveil its growth and the most productive authors, institutions, countries, journals, and journal categories. In addition, this study aimed to identify the recurring themes of the literature. On July 2023, the Web of Science Core Collection database was accessed with the following search query: TS = (*mogroside* OR "luo han guo" OR "lo han kuo" OR "monk fruit*" OR "monkfruit*" OR "Siraitia grosvenorii") AND TS = (sweet*). The search identified publications mentioning these terms in their title, abstract, or keywords. Only articles and reviews were included. No additional filters were placed on publication year, language, etc. Basic publication and citation frequency counts were recorded directly from the database. The complete record of the publications were exported into VOSviewer and CRExplorer, for visualization of recurring terms and identification of commonly cited references, respectively. The search yielded 155 publications. Publication and citation counts have increased steadily since the 2010s. The most productive authors and institutions were mostly based in Asian countries, such as China, Japan, and Singapore. Nearly half of the publications had contributions from China and were published in journals concerning food science technology. The health effects and biosynthesis of mogrosides were the recurring themes among the top 10 most cited publications. Most of the health effects, such as anti-hyperglycemic, anti-hyperlipidemic, and anti-diabetic properties, were demonstrated in animal models with limited evidence from clinical trials. Future studies should focus on testing in humans. Since monk fruit extracts were generally recognized as safe (GRAS) according to the Food and Drug Administration (FDA), the affirmation of these health benefits in humans by future studies should advocate its use in the food industry and the society to generally improve the public health.
    Keywords:  RPYS; VOSviewer; bibliometric; mogroside; monk fruit; non-nutritive sweetener
    DOI:  https://doi.org/10.3389/fnut.2023.1253255
  17. BMJ Open Ophthalmol. 2023 Sep;pii: e001330. [Epub ahead of print]8(1):
       OBJECTIVE: This study aimed to examine the publication patterns and present a current view of the field of uveitis using a bibliometric analysis.
    DESIGN: Bibliometric analysis.
    METHODS AND ANALYSIS: A comprehensive search of three databases including MEDLINE, EMBASE and Cochrane was conducted from 1 January 2000 to 31 December 2022. Search results from all three databases were subjected to analysis by Bibliometrix, an R programme that analyses large literature dataset with statistical and mathematical models. Visualisation of collaboration networks and relevance between countries was presented with VOSviewer.
    RESULTS: A total of 26 296 articles were included in the analysis. The field of uveitis has undergone a significant exponential growth since 2000, with an average growth rate of 4.14%. The most substantial annual growth was between the years 2021 and 2022 (36%). According to the corresponding author's countries, the three most productive countries were Turkey (3288, 12.6%), the USA (3136, 12%) and Japan (1981, 7.6%). The USA (243, 31.4%), England (117, 15%) and Germany (62, 8%) are the top three countries that contributed to clinical trials. The average international collaboration of all countries was 2.5%.
    CONCLUSIONS: Uveitis literature has undergone significant growth in the past two decades. The demographic factors of publishing countries lead to their various productivity and types of these uveitis studies, which is closely associated with the countries' scientific research resources and patient populations.
    Keywords:  Epidemiology; Eye (Globe); Infection; Inflammation; Macula; Ocular surface; Pathology; Vision
    DOI:  https://doi.org/10.1136/bmjophth-2023-001330
  18. Front Bioeng Biotechnol. 2023 ;11 1249667
      Background: Nanotechnology has been increasingly used in healthcare during recent years. However, the systematic evaluation of research on nanotechnology for pain management is lacking. In this study, we employed a bibliometric approach to examine the status of the research and global trends of nanotechnology in relation to pain management. Methods: We selected relevant papers published in the Web of Science Core Collection database between 2013 and 2022 using search terms related to nanotechnology and pain management. Subsequently, the following bibliographic information was collected: publication year, originating country/region, affiliated authors and institutions, published journal, references cited, citation frequency, and keywords. The bibliometric software programs VOSViewer and CiteSpace were employed to obtain bibliometric statistics and perform visual analysis. Results: A total of 2680 papers were retrieved. The number of publications in the field of nanotechnology for pain management has been increasing annually since 2013. China had the highest number of published papers, whereas the United States led in total citations. The Chinese Academy of Sciences was the most prolific institution, while the Tehran University of Medical Sciences had the highest overall citations. Furthermore, De Paula was the most prolific author. Papers associated with nanotechnology for pain management were mainly published in the International Journal of Pharmaceutics, Pharmaceutics, and the International Journal of Nanomedicine. Keyword analysis showed that "in-vitro" and "drug-delivery" appeared most frequently, with the top 10 common keywords comprising nanoparticles, pain, in-vitro, drug-delivery, delivery, release, inflammation, neuropathic pain, formulation, and expression. Lastly, the latest emerging keyword was "electrochemical sensor". Conclusion: Research on applying nanotechnology for pain management is growing steadily. China is the top country in terms of number of publications, with institutions under the Chinese Academy of Sciences making significant contributions to this field. "In-vitro" and "drug-delivery" are the current hotspots in this area, with "electrochemical sensor" as the latest topic at the research forefront. However, national and inter-institutional collaborations should be strengthened to enable patients with pain disorders to benefit from nanotechnology implementation in pain management.
    Keywords:  VOSviewer; bibliometrics; citespace; nanotechnology; pain management; trends; visualisation
    DOI:  https://doi.org/10.3389/fbioe.2023.1249667
  19. Front Endocrinol (Lausanne). 2023 ;14 1245719
      Polycystic ovary syndrome (PCOS) is a very common chronic disease and causes reproductive disorders in women of childbearing age worldwide. The cause of metabolic dysfunction in PCOS is unknown, and there is a lack of systematic bibliometric analysis for this disease. This study included 3,972 articles on metabolic dysfunction in PCOS published from 2012 to 2021. We applied the VOSviewer and the CiteSpace scientometric analysis software to analyze the data regarding the publication of the articles, countries, authors, institutions, scientific categories, cited journals, and keywords. Through this analysis, we determined the research efforts and their developing trends and anticipated the progress in understanding PCOS-related metabolic dysfunction.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; metabolism; polycystic ovary syndrome
    DOI:  https://doi.org/10.3389/fendo.2023.1245719
  20. Complement Ther Med. 2023 Sep 09. pii: S0965-2299(23)00071-7. [Epub ahead of print]78 102984
       OBJECTIVE: The study aims to investigate and visualize the hotspots of acupuncture for Allergic rhinitis (AR) over the past two decades and pinpoint future trends in this field.
    METHOD: We conducted a systematic search of English-language articles or reviews on acupuncture for AR in the Web of Science Core Collection from 2002 to 2022. Using Citespace, VOSviewer, and Bibliometrix, we analyzed and visualized the publications, countries, institutions, authors, journals, and keywords from various angles.
    RESULT: The study identified 197 documents, 80 journals, 458 keywords, and 928 authors associated with acupuncture for AR. Although article publication fluctuated over the past 20 years, an overall upward trend emerged, with rapid growth during the second decade. China contributed the most to acupuncture research on AR and had the closest collaborations with the United States and Germany. China Medical University was the most prolific institution, and Benno Brinkhaus was the most productive and influential author. The most published journal was Medicine, while the Journal of Allergy and Clinical Immunology was the most frequently cited journal. The highest frequency keywords included acupuncture, allergic rhinitis, and asthma. Randomized controlled trials and alternative & complementary medicine remained significant research hotspots, while rhinoconjunctivitis is expected to be the emerging focus of future investigations.
    CONCLUSION: acupuncture has experienced robust development for the treatment of allergic rhinitis over the last two decades, with rhinoconjunctivitis and clinical research being the anticipated trends and frontiers of future research.
    Keywords:  Acupuncture; Allergic rhinitis; Alternative and complementary medicine; Bibliometric; Visual analysis
    DOI:  https://doi.org/10.1016/j.ctim.2023.102984
  21. Int J Low Extrem Wounds. 2023 Sep 13. 15347346231200559
      Buruli ulcer is caused by Mycobacterium ulcerans, a skin infection that occurs mostly in people living in the developing economies of Africa and is considered a neglected tropical disease by the World Health Organization (WHO). Left untreated, it can lead to chronic wounds and loss of limbs. This disease is one of the target diseases of the WHO, and there are very limited bibliometric studies published on this subject. Also, no similar study using the Web of Science Core Collection was found in the available literature. The aim of this study was to evaluate the bibliometric analysis of the literature on Buruli ulcers. For data visualization and analysis, the open-source visualization program Biblioshiny (version 2.0) was used. Although most publications are from Ghana, the United States, and European countries have also made significant contributions. The number of publications has increased especially since 2016. The most preferred keywords in the publications were treatment, diagnosis, and transmission routes. This is the first bibliometric analysis that examines the trend of scientific publications on Buruli ulcer that have been indexed in the Web of Science. Our findings have the potential to be used by academics to improve their research.
    Keywords:  Buruli ulcer; Mycobacterium ulcerans; bibliometric; publication
    DOI:  https://doi.org/10.1177/15347346231200559
  22. BMC Oral Health. 2023 Sep 16. 23(1): 668
       BACKGROUND: The use of activated carbon (AC) in oral hygiene products has gained significant interest; however, its potential benefits for oral health remain uncertain. This study aimed to conduct a scientometric analysis to examine the dynamicity, emerging patterns, and trends over time in scientific production concerning the use of AC in oral health.
    METHODS: The Web of Science database was searched for articles published between 2005 and 2022. Various bibliometric indicators, including the H-index, annual growth, Lotka's law, Bradford's law, and Sankey diagram, were used for data analysis. Overlay maps, timezone visualization, and three field plots were used to evaluate visualization patterns, time-temporal relationships, and trends. Information retrieval process was performed on March 11, 2023.
    RESULTS: The analysis revealed that only six studies constituted the top references with the highest number of citations in recent years, with Brooks' 2017 study demonstrating the most significant increase in citation. The dual-map overlay demonstrated a close citation relationship between cluster 4 (Molecular Biology Immunology) and the areas of Environmental, Toxicology, and Nutrition. The visualization graph of publication patterns indicated the journals that accumulated the highest number of citations during the study period.
    CONCLUSION: This scientometric study provides valuable insights into the use of AC in oral health and its impact on the field of dentistry. It determines the most productive journals, authors, and countries with the greatest influence. AC effectively removes pollutants and is gaining interest for use in dental effluent treatment. Thus, it may be a viable option for professionals.
    Keywords:  Activated carbon; Bibliometrix; Oral health; Scientometric study; Web of Science
    DOI:  https://doi.org/10.1186/s12903-023-03375-3
  23. Front Cardiovasc Med. 2023 ;10 1228201
       Background: The increasing number of patients with refractory angina pectoris, combined with the aging population and improved survival rates among coronary heart disease patients, presents a significant challenge in contemporary cardiovascular medicine. The treatment of refractory angina has been an ongoing area of exploration, yet a comprehensive analysis of the existing literature on this topic is currently lacking. Therefore, this study aims to provide the first bibliometric analysis of publications related to refractory angina.
    Methods: A systematic search was conducted in the Web of Science database to identify articles related to refractory angina published between 2003 and 2022. The inclusion criteria were limited to articles and reviews written in English. CiteSpace software was utilized to conduct a collaborative network analysis of countries/regions, institutions and authors, co-occurrence analysis of keywords, and co-citation analysis of authors and references.
    Results: A total of 1,386 publications were identified, with an annual publication volume exhibiting fluctuation over time. American and European countries and institutions demonstrated a leading position in terms of research output. Henry TD emerged as the most prolific researcher in the field, while Mannheimer C received the highest number of citations. The primary research hotspot within this field focused on the treatment of refractory angina, with recent emphasis on emerging treatments such as stem cell therapy and the coronary sinus reducer. A significant number of clinical trials have been conducted, with a continuous focus on patient benefits, quality of life, and survival prognosis.
    Conclusion: Significant progress has been made in the field of refractory angina pectoris in recent years. Novel treatment methods, including spinal cord stimulation, enhanced external counterpulsation, stem cell therapy, and the coronary sinus reducer, hold promising therapeutic prospects. However, further high-quality evidence-based research is essential to support these emerging interventions. Additionally, the development of comprehensive evidence-based guidelines for refractory angina treatment is crucial. Such guidelines would provide clinicians with a framework to navigate the complexities of treatment choices and optimize patient care in this challenging condition.
    Keywords:  bibliometric analysis; cardiovascular diseases; citespace; knowledge mapping analysis; refractory angina
    DOI:  https://doi.org/10.3389/fcvm.2023.1228201
  24. Naunyn Schmiedebergs Arch Pharmacol. 2023 Sep 11.
      Recently, various studies have been devoted to the study of transient receptor potential vanilloid member 1 (TRPV1)-related diseases, potential drugs, and related mechanisms. The objective of this investigation was to examine the significant areas and cutting-edge developments in TRPV1 study within recent decades. Articles or reviews were obtained from the Web of Science Core Collection. VOSviewer 1.6.18 and CiteSpace 6.1 R2 software were utilized to examine publication growth, distribution by country/region, institution, journal, authorship, references, and keywords. The software identified keywords with a high citation burstiness to determine emerging topics. From 1990 to 2023, the annual global publications increased by 62,000%, from 1 to 621. Journal of neuroscience published the most manuscripts and Nature produced the highest citations. The USA, Seoul National University and Di marzo V were the most productive and impactful institution, country, and author, respectively. "TRPV1," "Capsaicin receptor," "Activation," and "Pain" are the most important keywords. The burst keywords "TRPV1 channel," "Oxidative stress," "TRPV1 structure," and "Cancer" are supposed to be the research frontiers. The present study offers valuable insights into the understanding of TRPV1 and pain-related conditions. The research on TRPV1 has demonstrated a steady increase in studies related to pain-related diseases in the past few decades. The significance of TRPV1 in cancer pathogenesis and the resolution of its structure will emerge as a new academic trend in this field, providing direction for more widespread and comprehensive studies in the future.
    Keywords:  Bibliometrics; CiteSpace; Transient receptor potential vanilloid member 1; VOSviewer; Visual analytics
    DOI:  https://doi.org/10.1007/s00210-023-02709-w
  25. Helicobacter. 2023 Sep 11. e13021
       BACKGROUND: Increasing evidence has indicated that Helicobacter pylori infection is associated with the complex microbiota in the digestive tract of the human body. We aimed to assess the research trends and hotspots in the field of H. pylori and microbiota using a quantitative method.
    MATERIALS AND METHODS: The clinical studies on H. pylori and microbiota published from 2001 to 2022 were extracted from the Web of Science database. We visualized and analyzed countries/regions, institutions, authors, journals, and keywords through VOSviewer and CiteSpace software. The test techniques, specimen type, as well as microbiota variation after H. pylori infection and eradication were also evaluated.
    RESULTS: A total of 98 publications were finally identified, and the number of annual papers increased gradually. China showed its dominant position in the publication outputs, and Nanchang University was the most productive institution. Cong He, Xu Shu, and Yin Zhu published the highest number of papers, whereas Helicobacter was the most productive journal. "Helicobacter pylori" ranked highest in the keyword occurrences. 16S rRNA gene sequencing was the most frequently used method for microbiota analysis. Fecal samples had the highest frequency of use, followed by gastric mucosa and saliva. H. pylori infection was associated with the alterations of microbiota through the digestive tract, characterized by the enrichment of Helicobacter in the stomach. Triple and quadruple therapy were the most utilized eradication regimens, and probiotics supplementation therapy has been proven to reduce side effects and restore microbial diversity.
    CONCLUSIONS: This bibliometric analysis provides an overview of advancements in the field of H. pylori and microbiota. While numerous studies have been conducted on the correlation between H. pylori and the alterations of microbiota, future research is warranted to investigate the mechanisms underlying the interplay between H. pylori and other microbes in the development of related diseases.
    Keywords:   Helicobacter pylori ; CiteSpace; VOSviewer; bibliometric analysis; microbiota; research trends
    DOI:  https://doi.org/10.1111/hel.13021
  26. Acta Chir Orthop Traumatol Cech. 2023 ;90(4): 233-238
      PURPOSE OF THE STUDY A global bibliometric comparison of the level of scientific interest and output in the two research areas hip and knee arthroscopy (H-ASC and K-ASC) was carried out. In addition, the different degrees of publication activity in the countries and institutes performing this research were investigated. MATERIAL AND METHODS Publications from 1945-2020 listed in the Web of Science Core Collection were included in the study. Using the web application Science Performance Evaluation (SciPE), quantitative and qualitative aspects were evaluated. Subsequently, the date of publication, author information, and other metadata were analysed. RESULTS Since 1945, 3,924 studies have been published on K-ASC and 2,163 on H-ASC. The majority of the publications which have appeared since 2016 dealt with the topic of H-ASC (H-ASC: 241.2 publications/year; K-ASC: 217.4 publications/year). The USA published the most on both topics (H-ASC: 1,123 publications; K-ASC: 1,078 publications). More countries and institutes participated in K-ASC (3,008 institutes, 82 countries) than in H-ASC (103 institutes, 57 countries). The ten institutes with the most publications accounted for 36.71% and 12.34% of all publications on H-ASC and K-ASC, respectively. H-ASC received 78.12% of its funding from private sponsors while K-ASC was supported mainly by governmental/nonprofit sponsors (70.92%). CONCLUSIONS This study provides the first scientific comparison between H-ASC and K-ASC. Measured by qualitative and quantitative aspects, K-ASC was the most flourishing research area overall. In the last ten to five years, interest has shifted towards HASC with an increasing number of publications and a higher rate of citations. Key words: knee arthroscopy, hip arthroscopy, bibliometric comparison.
  27. eNeurologicalSci. 2023 Dec;33 100476
       Background: Although female representation has been growing among physicians, women continue to be underrepresented in neurology, particularly regarding academic research in authorship and leadership. Analyzing recent trends in high-impact neurology journals highlights the underrepresentation of women and helps explore barriers to female representation in academic neurology.
    Methods and results: Journal Citation Reports (JCR) for 2021 was used to screen neurology journals for selection. The first 15 journals with the highest impact factors (JIF) were included. 15,404 total articles in neurology were examined for gender distribution of editorial staff and authorship with the highest total citations from January 1st, 2018 to October 31st, 2021. Gender was classified using biographical information from public and personal media sources. Genderize.io was used in cases of ambiguity, predicting gender at probability of ≥95%. Our data demonstrated that these journals only had 13% female editor-in-chiefs and 35% female editorial staff. The data further demonstrated that females accounted for 39% of first authors and 26% for last authors. During the four years examined males continued to account for the vast majority of both first and last authors for publications accepted and journal editorial staff members.
    Conclusion: Women are significantly under-represented in the field of neurological research in leadership positions as editor-in-chiefs, editorial board members as well as first or senior authors in top neurology medical journals. With continued underrepresentation of women occupying leading publishing roles, parity with men is still a work in progress. Additional work is needed to identify and address barriers to academic advancement for women physicians in academic neurology.
    Keywords:  Barriers; Editor in chief; Editorial staff; High impact factor; Parity HeforShe campaign; Underrepresented
    DOI:  https://doi.org/10.1016/j.ensci.2023.100476
  28. Environ Sci Pollut Res Int. 2023 Sep 11.
      The management of waste through dual way of recycling (i-e offline and online) is assumed to have a key role in attaining ecological sustainability and enabling circular practices. The research on online recycling is gaining evolution in recent age. Prior literature on the current research theme has failed to provide a comprehensive outlook and future trend. Therefore, the current research intends to elaborate the current research scenario linked with online recycling by critically scrutinizing the prior research over the last 41 years. A comprehensive analysis was conducted using the Scopus database, retrieving a total of 866 articles. These articles were selected to provide a conceptual overview and understanding of the fundamental research conducted in the field. By employing bibliometric analysis this research provides comprehensive detail about evolution, mapping of publications and prominent trends from the year 1981 to 2022 to understand the practices and future trends of online recycling research. The outcomes elucidated that there is exponential increase in research publications relating to online recycling over the last five years. The most influential producer of online recycling research are China, United Kingdom and United States. Chinese Universities has the highest number of publications among all the countries across globe. Moreover, the current research trend is focused on technology based circular economy, industrial ecology, bio-based waste management, dual channel recycling, municipal waste, waste from electrical and electronic equipment (WEEE), environmental impact and lifecycle assessment. Hence, the prominent research perspective and highlighted features could offer recommendation for upcoming studies to contribute in literature and help practitioners, policymakers and professionals move towards circular practices.
    Keywords:  Bibliometric analysis; Digital technologies; Ecological sustainability; Environmental performance; Recycling; Waste management
    DOI:  https://doi.org/10.1007/s11356-023-29537-y
  29. J Orthop Surg (Hong Kong). 2023 Sep-Dec;31(3):31(3): 10225536221135471
       PURPOSE: Research is vital for evidence-based surgery. Understanding scientometric differences among surgical specialties has scope to inform discussions within and across surgical specialities to develop and maintain a culture of research productivity. This study aims to quantify Australian orthopaedic surgical academic productivity compared to the other specialties within the Royal Australasian College of Surgeons' (RACS).
    METHODS: A list of Australian surgeons registered with RACS was compiled using the "find a surgeon" function on the RACS Web site. This list was cross-referenced with the specialty databases on their respective websites. A name search of the SCOPUS database for each individual surgeon was performed. For each individual h-index, m-index, total active publishing years, total publications, and total citations were collected.
    RESULTS: Orthopaedic surgeons had the equal lowest h-index median 2 (interquartile range:3), the shortest duration involved in research median 5 years (14), produced the fewest articles median 2 (7) and attained the second lowest number of citations median 28 (116) of the Australian surgical specialties. When the 10 individuals with highest h-index are compared among specialties, orthopaedic surgeons rank second with a median of 37 (6.5).
    CONCLUSION: Our objective data provides a factual comparison and baseline assessment of one aspect of research productivity. It can challenge currently held perceptions of performance and can inform conversations about strategic development. We recommend this assessment to other international Colleges and Societies on regular basis. These accurate academic productivity metrics provide opportunity for developing and maintaining a culture of sustained, significant contribution to surgical research.
    Keywords:  academic output; bibliometry; citations; hindex; orthopaedics; scientometry; surgery
    DOI:  https://doi.org/10.1177/10225536221135471
  30. Quant Imaging Med Surg. 2023 Sep 01. 13(9): 5605-5621
       Background: Computed tomography-derived fractional flow reserve (CT-FFR) is a non-invasive imagological examination used for diagnosing suspected coronary atherosclerotic heart disease, providing the morphological and functional value on a three-dimensional (3D) coronary artery model. This article aimed to collate the existing knowledge and predict this novel technology's future research hotspots.
    Methods: To collect data, 1,712 articles were retrieved from the Web of Science Core Collection (WoSCC) database from 2012-2022. CiteSpace5.8.R3 was used to visually analyze the research status and predict future research hotspots.
    Results: Firstly, the United States, China, and the Netherlands were identified as the countries having published the most articles about CT-FFR. Jonathan Leipsic's group ranked first for the highest number of published articles. Secondly, the visualized analysis indicated that the exploration of CT-FFR is multi-disciplinary and involves cardiology, radiology, engineering, and computer science. Thirdly, the hotspots in this field, which were inferred from the keyword distribution and clustering, included the following: "diagnostic performance", "accuracy", and the "prognostic value" of CT-FFR, and comparison of CT-FFR and other imaging methods sharing similarities. The research frontiers included technologies utilized to obtain more accurate CT-FFR values, such as artificial intelligence (AI) and deep learning.
    Conclusions: As the first visualized bibliometric analysis on CT-FFR, this study captured the current accumulated information in this field and offer more insight and guidance for future research.
    Keywords:  Bibliometrics; CiteSpace; artificial intelligence (AI); computed tomography-derived fractional flow reserve (CT-FFR); coronary heart disease (CHD)
    DOI:  https://doi.org/10.21037/qims-22-1094
  31. Environ Sci Pollut Res Int. 2023 Sep 14.
      Blasting constitutes an essential component of the mining and construction industries. However, the associated nuisances, particularly blast vibration, have emerged as significant concerns that pose threats to operational stability and the safety of the surrounding areas. Given the increasing emphasis on sustainability, ecological responsibility, safety, and geo-environmental practices, the impact of blast vibration has garnered heightened attention and scrutiny. Nevertheless, the field still lacks comprehensive phase analysis studies. Therefore, it is imperative to elucidate the research progress on blast vibration and discern its current frontiers of investigation. To address this need, this study employs bibliometric methods and the CiteSpace 6.1.R2 software to analyze 3093 papers from the Web of Science database. Through this comprehensive analysis, the study aims to chronicle the developmental trajectory, assess the present research status, and identify future trends in the field of blast vibration. The findings of this study reveal that research on "blasting vibration" is advancing rapidly, with the number of citations exhibiting a J-shaped growth curve over time. China emerges as the leading contributor to this research, followed by India, and the foremost institution in this field is Central South University in China. Cluster analysis identifies the effects of ground vibration, numerical simulation, blast load, blasting vibration and rockburst hazard as the most prominent research areas presently. The primary research directions in this domain revolve around the rock fragmentation, compressive strength, particle swarm optimization, and ann. The emergence of these keywords underscores a dynamic shift towards a more holistic and multidisciplinary approach in the field of blasting-induced ground vibration. Furthermore, this study provides a concise overview of blast vibration, discusses prediction techniques, and proposes measures for its control. Additionally, the discussion delves into the social significance of intelligent blasting systems within the context of artificial intelligence, aiming to address the hazards associated with blast-induced ground vibrations.
    Keywords:  Blasting vibration; CiteSpace; Knowledge map; Scientometrics
    DOI:  https://doi.org/10.1007/s11356-023-29712-1
  32. J Surg Res. 2023 Sep 07. pii: S0022-4804(23)00361-X. [Epub ahead of print]292 324-329
       INTRODUCTION: With the advent of social media and the associated increase in connectivity between scientists and the lay public, the Altmetric Attention Score has been created as a way to measure these interactions between scholarly publications and media dissemination. Little is known, however, whether these types of media exchanges measured by Altmetrics may serve as a proxy for public engagement. As such, we have sought to determine whether or not an association exists between Altmetric scores and public engagement, as measured by article citation in a health policy document.
    METHODS: The top 100 highest scoring articles in the medical and health sciences with respect to Altmetric Attention Scores were selected from each of 3 y (2014, 2015, and 2016). Each article was then matched to an article from the same year and journal with the highest Relative Citation Ratio (RCR) for comparison. Bivariate analysis compared article groups with respect to citation in a public policy document, open-access status, and funding status, as well as Altmetric and RCR scores. A multivariable model was then constructed to identify significant factors associated with citation in a public policy document. Finally, a contour plot was generated in order to estimate the interaction between Altmetric Scores and RCR and their comparative effects on the probability of inclusion in a health policy document.
    RESULTS: Of the 600 articles included in the analysis, 286 (48%) had been cited by a public policy article. The only difference that existed between the cohorts was for funding status, with 55 articles (40%) in the RCR cohort having received funding compared to 81 (60%) in the Altmetric cohort (P = 0.011). On bivariate analysis, both Altmetric (P = 0.0018) and RCR (P < 0.0001) scores were independently predictive of policy citation. In a multivariable model, the interaction between Altmetric Scores and RCR with respect to policy inclusion was significant (OR = 1.22; 95% CI = 1.08-1.38) and a contour plot demonstrates that either high Altmetric score or RCR alone is sufficient to generate a high probability of policy inclusion.
    CONCLUSIONS: Scholarly article Altmetric Scores may serve as a novel means to explore public engagement in scientific research and health policy. In addition, journals that aim to impact public policy through article dissemination may benefit from engagement in social media avenues in addition to traditional citation pathways in order to encourage broader inclusion.
    Keywords:  Altmetric; Bibliometrics; Citation; Public policy; RCR
    DOI:  https://doi.org/10.1016/j.jss.2023.07.051
  33. Zhongguo Zhen Jiu. 2023 Sep 12. 43(9): 996-1005
      Bibliometric and scientific knowledge graph methods were used to analyze the research status and hot spots of acupuncture-moxibustion in treatment of myofascial pain syndrome (MPS) and explore its development trend. The articles of both Chinese and English versions relevant to MPS treated by acupuncture-moxibustion were searched in CNKI, VIP, Wanfang, SinoMed and WOS from the database inception to March 20, 2023. Using Excel2016, CiteSpace6.2.R2 and VOSviewer1.6.18, the visual analysis was conducted by means of the cooperative network, keyword co-occurrence, keyword timeline, keyword emergence, etc. From Chinese databases and WOS database, 910 Chinese articles and 300 English articles were included, respectively. The annual publication volume showed an overall rising trend. Literature output of English articles was concentrated in Spain, China, and the United States, of which, there was less cross-regional cooperation. In the keyword analysis, regarding acupuncture-moxibustion therapy, Chinese articles focused on "acupuncture", "electroacupuncture" and "acupotomy"; while, "dry needling" and "injection" were dominated for English one. Clinical study was the current hot spot in Chinese databases, in comparison, the randomized controlled double-blind clinical trial was predominant in WOS. Both Chinese and English articles were limited in the report of mechanism research. The cooperation among research teams should be strengthened to conduct comparative research, dose-effect research and effect mechanism research with different methods of acupuncture-moxibustion involved so that the evidences can be provided for deeper exploration.
    Keywords:  acupuncture-moxibustion; bibliometric analysis; myofascial pain syndrome; visualization graph
    DOI:  https://doi.org/10.13703/j.0255-2930.20230119-k0002
  34. Asian J Surg. 2023 Sep 13. pii: S1015-9584(23)01400-8. [Epub ahead of print]
      
    Keywords:  Bibliometric analysis; Bone metastases; Breast cancer
    DOI:  https://doi.org/10.1016/j.asjsur.2023.08.231
  35. Front Psychol. 2023 ;14 1213397
      A comprehensive cross-national understanding of the classroom learning environment (CLE) is critical to advancing CLE's development. This study compares the English and Chinese CLE literature to enhance a complete understanding of CLE. We conducted bibliometric analysis on 3,130 English literature from Social Sciences Citation Index (SSCI) and 1,261 Chinese literature from the Chinese Social Sciences Citation Index (CSSCI). The results show that both Chinese and English literature focus on the influence of CLE on students' cognitive and affective learning outcomes and the incorporation of information technology in CLE. The results also reveal the differences between Chinese and English literature from two perspectives: (1) Chinese CLE research mainly focuses on English education, and English CLE research mainly focuses on science education and (2) Chinese CLE research mainly analyzed the pedagogical aspect of CLE, while English CLE research focused on CLE's social and psychological aspects. We also discussed that future research should focus on (1) the balance of analyzing CLE from the perspective of students and other educational stakeholders such as teachers and school leaders, (2) student differences from the pedagogical level, (3) the physical level of CLE, (4) the use of statistical methods such as structural equation modeling that can analyze the mechanisms underlying the effects of CLE on student learning, and (5) the interdisciplinary research on CLE.
    Keywords:  bibliometric analysis; classroom learning environment; pedagogical aspect; social and psychological aspect; structural equation modeling
    DOI:  https://doi.org/10.3389/fpsyg.2023.1213397
  36. EClinicalMedicine. 2023 Oct;64 102174
       Background: While gender equity among academic authors has been extensively investigated, there is a significant gap in our understanding of racial/ethnic authorship trends, despite the recognition of barriers to authorship along both ethnic and gender lines. Leveraging the meta-data for all articles published in The British Medical Journal (The BMJ) and the Lancet and between 2002 and 2022 (inclusive), we explore demographic trends among UK academic medicine authors in two of the world's leading British medical journals.
    Methods: We systematically searched PubMed's MEDLINE for all articles published in The BMJ and Lancet between January 1st 2002 and December 31st 2022. Filtering for articles with a UK affiliation, we predicted gender using a publicly-validated name-to-gender dictionary, while data was analysed to explore and investigate ethnicity using the Consumer Data Research Centre's (CDRC) Ethnicity Estimator. Data was analysed to explore and investigate: (a) the proportion of female/male author publications, (b) the proportion of the various UK author ethnicity groups, and (c) the overlap/intersection between gender and ethnic identities among first and last authors. This comprehensive longitudinal analysis was conducted on 82,143 articles (51,209 from The BMJ and 30,934 from the Lancet) which represents >97% of all published articles between 2002 and 2022. As we sought to understand how academic authorship reflects the diversity of the UK population, we limited our analysis to first and last authors who had a UK affiliation and excluded "news" and "comments" pieces (16,736 articles for The BMJ and 4678 articles from the Lancet). The main outcome measures were the trends in first and last authorship demographics of academic medicine, focusing on the proportion of female/male authors, ethnicity and their intersectionality.
    Findings: Our findings show that, while women have made substantial headway towards equity among first and last authorship in The BMJ (peaking at 42% and 43%), they remain under-represented in the Lancet (35% and 27%). In both The BMJ and Lancet, Black authors have remained severely under-represented as both first and last authors (below 1% for most of the two decades), while Asian authors have increased proportionally to match their fraction in the general population (ranging from 2 to 10%).
    Interpretation: Analysis over the past two decades has shown that the gender author gap is decreasing quickly in The BMJ and Lancet. However, despite the two journals' growing focus on structural inequalities in medical academia, little progress has been made in rectifying the large gap between White British authors and other ethnic groups, especially Black authors. Without more awareness, diversity initiatives which have resulted in positive gains for White women do not seem to translate well for authors of colour.
    Funding: None.
    Keywords:  Authorship analysis; Ethnicity; Gender; Publication trends
    DOI:  https://doi.org/10.1016/j.eclinm.2023.102174
  37. Int J Biol Macromol. 2023 Sep 09. pii: S0141-8130(23)03606-1. [Epub ahead of print] 126709
      Magnetic biocatalysts combine magnetic properties with the catalytic activity of enzymes, achieving easy recovery and reuse in biotechnological processes. Lipases immobilized by magnetic nanoparticles form most. This review covers an advanced bibliometric analysis and an overview of the area, elucidating research advances. Using WoS, 34,949 publications were analyzed and refined to 450. The prominent journals, countries, institutions, and authors that published the most were identified. The most cited articles showed research hotspots. The analysis of the themes and keywords identified five clusters and showed that the main field of research is associated with obtaining biofuels derived from different types of sustainable vegetable oils. The overview on magnetic biocatalysts showed that these materials are also employed in biosensors, photothermal therapy, environmental remediation, and medical applications. The industry shows a significant interest, with the number of patents increasing. Future studies should focus on immobilizing new lipases in new materials with magnetic profiles, aiming to improve the efficiency of the different applications even more.
    Keywords:  Feedstock; Immobilization; Lipase; Magnetic biocatalysts; Magnetic nanoparticles
    DOI:  https://doi.org/10.1016/j.ijbiomac.2023.126709
  38. Front Res Metr Anal. 2023 ;8 1235208
      The term "dark citations," which has been previously used to refer to citations of information products outside of traditional peer-reviewed journal articles, is adapted here to refer to those that are not linked to a known indexed identifier and are effectively invisible to traditional bibliometric analysis. We investigate an unexplored source of citations in the biomedical and public health literature by surveying the extent of dark citations across the U.S. government. We systematically focus on public health, quantify their occurrences across the government, and provide a comprehensive dataset for all dark citations within PubMed.
    Keywords:  bibliometrics; dark citations; governmental resources; non-indexed information resources; web-based resources
    DOI:  https://doi.org/10.3389/frma.2023.1235208
  39. Sci Total Environ. 2023 Sep 12. pii: S0048-9697(23)05643-7. [Epub ahead of print] 167018
      Microcystin-leucine arginine (MC-LR) is a typical cyanobacterial toxin, and the threat of this toxin is increasing among organisms. Despite extensive toxicological studies on MC-LR, there is no comprehensive analysis based on previously published data. Therefore, we conducted bibliometric analysis and meta-analysis to identify research hotspots and to elucidate the key mechanism of the relationship between MC-LR and genotoxicity and neurotoxicity among fish and mammals. One of the hotspots is toxic mechanisms (indicated by the frequent appearance of oxidative stress, DNA damage, apoptosis, neurotoxicity, genotoxicity, ROS, comet assay, signalling pathway, and gene expression indicate as keywords). The density visualization shows a high frequency of "microcystin-LR" and "toxicology," and the overlay visualization emphasizes the prominence of "neurotoxicity" in recent years. These findings confirm the importance of studying MC-LR toxicity. Meta-analysis indicated that in both fish and mammals, MC-LR exposure increased ROS levels by 294 % and increased DNA damage biomarkers by 174 % but decreased neurotoxicity biomarkers by 9 %. Intergroup comparisons revealed that the exposure concentration of MC-LR was significantly correlated with genotoxicity and neurotoxicity levels in both fish and mammals (p < 0.05). Furthermore, the random forest (RF) model revealed that exposure concentration was the primary determinant associated with the induction of ROS, genotoxicity, and neurotoxicity induced by MC-LR. This is likely the dominant mechanism by which excessive ROS production induced by MC-LR causes oxidative stress, ultimately leading to genotoxicity and neurotoxicity in both fish and mammals.
    Keywords:  Bibliometric analysis; Fish; Mammals; Meta-analysis; Microcystin-LR
    DOI:  https://doi.org/10.1016/j.scitotenv.2023.167018
  40. Chemosphere. 2023 Sep 09. pii: S0045-6535(23)02353-6. [Epub ahead of print]341 140083
      Electrochemical advanced oxidation processes (EAOPs) have emerged as a promising approach for efficient wastewater treatment. However, despite their promising potential, there is a lack of comprehensive analysis regarding the research trends, bibliometric data, and research frontiers of EAOPs. To address this gap, this study conducted a thorough and comprehensive analysis of 2347 related articles in the Web of Science Core Collection Database from 2012 to 2022. The analysis included information on countries, authors, institutions, and more, with a focus on summarizing trends and cutting-edge research hotspots in the field. The University of Barcelona in Spain is the most effective institution. Brillas E. is the most productive author in the world. Research hotspots in EAOPs have evolved from traditional anodic oxidation (AO) to novel electro-Fenton (EF) technology, which focuses on efficient generation of H2O2 and the use of metal-organic frameworks to enhance performance and efficiency. Through systematic research hotspot analysis, the importance of performance comparison of different types of EAOPs, development of new materials, optimization of device parameters, and toxicity assessment of byproducts is highlighted. Concurrently, the rise and mechanisms of emerging EAOPs are predicted and analyzed. Finally, future research on EAOPs technologies should focus on technological coupling, development of new materials, reduction of energy consumption and cost, evaluation and minimization of toxicity, and exploration of green renewable energy sources for larger-scale applications in wastewater treatment pilot plants. In this way, these technologies can contribute to the sustainability of larger industrial wastewater treatment applications and make an important contribution to environmental protection and scientific and technological progress.
    Keywords:  Bibliometrics; EAOPs; Research progress; Sustainability; Wastewater treatment
    DOI:  https://doi.org/10.1016/j.chemosphere.2023.140083
  41. Accid Anal Prev. 2023 Sep 09. pii: S0001-4575(23)00336-6. [Epub ahead of print]192 107289
      Driver workload (DWL) is an important factor that needs to be considered in the study of traffic safety. The research focus on DWL has undergone certain shifts with the rapid development of scientific and technological advancements in the field of transportation in recent years. This study aims to grasp the state of research on DWL by both bibliometric analysis and individual critical literature review. The knowledge structure and development trend are described using bibliometric analysis. The knowledge mapping method is applied to mine the available literature in depth. It is discovered that one of the current research focus on DWL has shifted towards investigating its application in the field of autonomous driving. Subjective questionnaires and experimental tests (including both simulation technology and field study) are the main approaches to analyze DWL. An individual critical literature review of the influencing factors, measurement, and performance of DWL is provided. Research findings have shown that DWL was highly impacted by both intrinsic (e.g., age, temperament, driving experience) and external factors (e.g., vehicles, roads, tasks, environments). Scholars are actively exploring the combined effects of various factors and the level of vehicle automation on DWL. In addition to assess DWL by using subjective measures or physiological parameter measures separately, studies have started to improve classification accuracy by combining multiple measurement methods. Safety thresholds of DWL are not sufficiently studied due to the various interference items corresponding to different scenarios, but it is expected to quantify the DWL and find the threshold by establishing assessment models considering these intrinsic and external multiple-factors simultaneously. Driver or vehicle performance indicators are controversial to measure DWL directly, but they were suitable to reflect the impact of DWL in different driving conditions.
    Keywords:  Bibliometric analysis; Driver workload; Individual critical literature review; Influence factors; Measurement approach; Performance
    DOI:  https://doi.org/10.1016/j.aap.2023.107289
  42. Spine J. 2023 Sep 08. pii: S1529-9430(23)03372-7. [Epub ahead of print]
       PURPOSE: To examine ten-year trends in gender representation in speaking roles at major spine conferences.
    BACKGROUND CONTEXT: Medical conferences play an important role in career opportunities. There is little analysis on gender representation of major spine conferences despite several studies demonstrating gender disparities within spine surgery.
    STUDY DESIGN: Observational study SAMPLE: 20,181 abstract speakers across 10 years of academic conferences for six spine societies OUTCOME MEASURES: Percent of female abstract presenters MATERIALS AND METHODS: We collated the annual meeting programs of 6 major spine conferences (North American Spine Society (NASS), Scoliosis Research Society (SRS), International Meeting on Advanced Spine Techniques (IMAST), Global Spine Congress (GSC), American Association of Neurological Surgeons/Congress of Neurological Surgeons (AANS/CNS) Spine Summit, and the Cervical Spine Research Society (CSRS)) dating from 2013-2022. Departmental websites, society webpages, or personal social media were identified for images or the use of gendered pronouns in order to determine speaker gender for each speaker type. All categorical variables were compared using Pearson chi-square analysis.
    RESULTS: Women constituted 1,816 (9.0%) of all 20,181 identified conference speakers. Female representation was highest at NASS (N=680, 12.2%) but lowest at CSRS (6.6%) and GSC (7.1%). Spine Summit (7.4%), IMAST (9.92%), and GSC (9.87%) demonstrated the largest annual percent increases in female representation. Institutions in Middle East and Africa (1.4%), and Central and South America (1.8%) supported the lowest percent of female speakers. Women were significantly less likely to be speakers or moderators/course faculty than to be podium abstract presenters (p<0.001). The percent of women as invited speakers (10.4% vs. 5.5%, p=0.001) and moderators (11.4% vs. 3.7%, p<0.001) increased significantly over the study period, with annual increases of 8.8% and 20.8%, respectively, from 2013-2022 (p<0.001).
    CONCLUSIONS: While academic spine societies have made significant progress in promoting gender representation, especially among invited speakers and session moderators, women continue to be underrepresented compared to the percent of women in orthopedic and neurological surgery.
    Keywords:  academic conferences; disparities; gender; neurosurgery; orthopedic surgery; podium presentations; speakers; spine
    DOI:  https://doi.org/10.1016/j.spinee.2023.08.024
  43. J Acad Ophthalmol (2017). 2023 Jul;15(2): e178-e183
      Background  Gap years following medical school graduation have become more common, but research into their tangible career benefit is lacking. Examining the impact of gap years on resident scholarly productivity in ophthalmology may provide insight generalizable to all specialties. Objective  To evaluate whether a gap year following medical school graduation significantly predicts scholarly productivity during ophthalmology residency. Methods  In December 2021, residents were recorded from 110 publicly available American ophthalmology residency program webpages. They were included if educational history was listed on publicly accessible academic and social media profiles. Residents were then stratified into gap year and nongap year cohorts. Publication data were recorded from Scopus and PubMed. Pearson's chi-square, independent sample t -tests, and multivariable regression were performed. Results  A total of 1,206 residents were analyzed, with 1,036 (85.9%) residents taking no gap year and 170 (14.1%) residents with at least one gap year. Gap year residents were predicted to have increase in the likelihoods of publishing at least one, two, or five total articles during residency, in addition to at least one article in a high-impact journal. There was no significant relationship between gap years and publications with senior authors affiliated with either the resident's medical school or residency program. Conclusion  Residents taking gap years following graduation may publish more during residency, but these publications are not associated with senior authors at their institutions. Future investigations should continue to evaluate the significance of gap years in medical education.
    Keywords:  education; gap year; research productivity; residency; training
    DOI:  https://doi.org/10.1055/s-0043-1774400
  44. J Bone Joint Surg Am. 2023 Sep 15.
       BACKGROUND: In the current era of evidence-based medicine, scientific publications play a crucial role in guiding patient care. While the lack of diversity among orthopaedic surgeons has been well documented, little is known about the diversity of orthopaedic journal editorial boards. The purpose of this study was to assess the racial/ethnic and gender diversity of U.S. orthopaedic journal editorial boards.
    METHODS: The editorial boards of 13 orthopaedic journals were examined, including 10 subspecialty and 3 general orthopaedic journals. Race/ethnicity and gender were determined for each editorial board member. The representation observed on orthopaedic journal editorial boards was compared with representation at other phases of the orthopaedic pipeline, as well as within the various subspecialty fields of orthopaedics. Logistic regression and t tests were used to evaluate these comparisons.
    RESULTS: We identified 876 editorial board members of the 13 journals; 14.0% were Asian, 1.9% were Black, 1.9% were Hispanic, 2.4% were multiracial/other, and 79.7% were White. Racial/ethnic representation was similar across the subspecialty fields of orthopaedics (p > 0.05). The representation of women on orthopaedic editorial boards was 7.9%, with differences in gender diversity observed across subspecialty fields (p < 0.05). Among journals in the subspecialty fields of spine and trauma, female editorial board representation was lower than expected, even after taking into account the representation of women in these subspecialty fields (2.0% versus 9.0% [p = 0.002] and 3.8% versus 10.0% [p = 0.03], respectively).
    CONCLUSIONS: In this study of 13 subspecialty and general orthopaedic journals, the representation of racial/ethnic minorities and women on editorial boards was similar to their representation in academic orthopaedics. However, these values remain low in comparison with the population of patients treated by orthopaedic surgeons. Given the importance of scientific publications in the current era of evidence-based medicine, orthopaedic journals should continue working to diversify the membership of their editorial boards.
    DOI:  https://doi.org/10.2106/JBJS.23.00384
  45. Int Heart J. 2023 Sep 13.
      Participation in clinical research has served clinicians to develop academic careers, as well as to deepen clinical insights, implement evidence-based medicine practices, and even inspire new clinical questions. Early engagement in academic pursuits may better prepare clinicians to maintain long-term research productivity, rather than starting later in their careers.We included medical doctors who graduated from a medical university and retrospectively followed them for 10 years after graduation. The impact of at least one publication within the first 5 years on the achievement of ≥ 5 publications within 10 years was evaluated.A total of 79 medical doctors, including 60 (76%) men, were included. During the first 5 years, 21 (27%) published at least one paper. Overall, 25 (32%) achieved the primary outcome. At least one publication during the first 5 years was an independent predictor of the primary outcome (odds ratio 30.4, 95% confidence interval 2.68-251, P = 0.002). Medical doctors with at least one publication within the first 5 years had significantly higher cumulative 10-year publications compared to no publications within the first 5 years (9 [5, 13] versus 0 [0, 3], P < 0.001).In this retrospective study, we demonstrated that an early involvement in research defined by academic output was associated with higher odds of multiple publications later in a career. Prospective studies to validate our findings by involving young medical doctors in academic pursuits are needed to understand the longitudinal effects of early career academic productivity.
    Keywords:  Medical education; Resident
    DOI:  https://doi.org/10.1536/ihj.23-259
  46. Environ Sci Pollut Res Int. 2023 Sep 13.
      The circular economy (CE) and bioeconomy (BE) are recognized as potential solutions for achieving sustainable development, yet little research has examined their potential contribution to the United Nations' Sustainable Development Goals (SDGs). In this study, we conducted a bibliometric analysis of 649 articles published between 2007 and 2022, as well as a systematic literature review of 81 articles, to assess the extent to which the CE and BE communities have addressed the SDGs. Our analysis identified 10 research gaps including the limited number of empirical quantitative papers, particularly in the context of BE, and the underrepresentation of developing regions such as Latin America and Africa in the literature. Our main finding reveals that the CE community primarily focuses on SDG 12, Responsible Consumption and Production, followed by SDG 9, Industry, Innovation, and Infrastructure; SDG 7, Affordable and Clean Energy; and SDG 6, Clean Water and Sanitation. The BE community, on the other hand, focuses primarily on SDG 7, followed by SDG 9 and SDG 12. However, both communities lack attention to social SDGs such as quality education, poverty, and gender equality. We propose that a combination of CE and BE, known as circular bioeconomy, could help countries achieve all SDGs. Further research is needed to develop and implement circular bioeconomy policies that address these gaps and promote sustainable development. In this sense, our study identified an important research gap that needs more attention in the future.
    Keywords:  Bibliometrics; Circular bioeconomy (CBE); Global agenda; Sustainability; Sustainable development agenda; United Nations (UN)
    DOI:  https://doi.org/10.1007/s11356-023-29632-0
  47. J Surg Res. 2023 Sep 08. pii: S0022-4804(23)00346-3. [Epub ahead of print]293 22-27
       INTRODUCTION: There is a gender gap in the surgical field worldwide. Brazil and low- and middle-income countries generally tend to have a more profound gap. Therefore, we aim to assess the gender distribution in Brazilian surgical residencies.
    METHODS: From a national residencies' database, we collected residency entering years, names, and surgical subspecialties. We classified gender from the names using Gender API software and performed linear regression, binomial, and chi-square tests.
    RESULTS: From 81,979 doctors (1931-2020), 36.6% were women (P < 0.001). Of 13 subspecialties, regarding the absolute numbers of women, only neurosurgery and plastic surgery did not significantly differ between gender per year. There was a statistically significant growth in the proportional rates of female representation among most of the surgical residencies analyzed. Overall, the least women's representation was in urology (3.8%). From all subspecialties analyzed, both genders had a significant linear absolute increase over the years (P < 0.05), except for obstetrics-gynecology and pediatric surgery for men. Until 1990, all surgical programs had at least one woman resident, except for colorectal surgery.
    CONCLUSIONS: Although there is an overall lack of women surgeons in Brazil, we observed an increase in women in surgical residencies. Therefore, the study may demonstrate a future change in the Brazilian gender equity scenario and reflect the growing representation of women in medicine in Brazil, except for some surgical specialties.
    Keywords:  Brazil; Gender distributions; Surgical residencies; Time analysis; Women in surgery
    DOI:  https://doi.org/10.1016/j.jss.2023.07.039
  48. Nature. 2023 Sep 15.
      
    Keywords:  Careers; Ocean sciences; Publishing; Research management
    DOI:  https://doi.org/10.1038/d41586-023-02877-y