bims-evares Biomed News
on Evaluation of research
Issue of 2023–08–27
fifty-two papers selected by
Thomas Krichel, Open Library Society
  1. Bibliometric and correlation analysis of bariatric surgery researches in Asia-Pacific from 2000 to 2021.
  2. Global Trends and Hotspots on Microglia Associated with Pain from 2002 to 2022: A Bibliometric Analysis.
  3. Trends and hotspots of publications on ferroptosis: A 10 Year overview.
  4. Bibliometric analysis of the 100 most cited articles in nonspecific neck pain research: A STROBE-compliant study.
  5. Bibliometric Analysis of Research on Temporomandibular Joint and Occlusion from 2000 to 2022.
  6. Thyroid Nodules: Emerging trends in Detection and Visualization based on Citespace.
  7. Thirty years of research on photoacoustic imaging in the field of cancer: A scientometric analysis of hotspots, bursts, and research trends.
  8. Artificial intelligence in orthodontics and orthognathic surgery: a bibliometric analysis of the 100 most-cited articles.
  9. Bibliometric analysis of the global publication activity in the field of relapsing polychondritis during 1960-2023.
  10. Bibliometric Analysis of Global Trends in Research on Seasonal Variations in Gut Microbiota from 2012 to 2022.
  11. Mapping scientific knowledge discovery on COVID-19 pandemic and agriculture: a bibliometric analysis and future research directions.
  12. A bibliometric systematic review of extracellular vesicles in eye diseases from 2003 to 2022.
  13. Gut microbiota and eye diseases: a bibliometric study and visualization analysis.
  14. Bibliometric study of immunotherapy for hepatocellular carcinoma.
  15. The application of metagenomic next-generation sequencing in pathogen diagnosis: a bibliometric analysis based on Web of Science.
  16. Stakeholder governance and sustainability in football: A bibliometric analysis.
  17. A swift expanding trend of extracellular vesicles in spinal cord injury research: a bibliometric analysis.
  18. Research Hotspots and Trends of Bone Xenograft in Clinical Procedures: A Bibliometric and Visual Analysis of the Past Decade.
  19. Global Trend on Machine Learning in Helicobacter within One Decade: A Scientometric Study.
  20. What we know about grief intervention: a bibliometric analysis.
  21. Scientific literature on neglected tropical diseases: a bibliometric analysis.
  22. A Century of Evolution in Spine Surgery Publications: A Bibliometric Analysis of the Field From 1900 to 2023.
  23. Altmetric analysis of the most mentioned articles online in the orthopaedic literature.
  24. Bibliometric analyses of global output on neuromyelitis optica spectrum disorder.
  25. Global trends and current status of amputation: Bibliometrics and visual analysis of publications from 1999 to 2021.
  26. Trends in the Use of Lipases: A Systematic Review and Bibliometric Analysis.
  27. Out-of-hospital cardiac arrest: A data-driven visualization of collaboration, frontier identification, and future trends.
  28. Global trends in research of mitophagy in liver diseases over past two decades: A bibliometric analysis.
  29. A bibliometric analysis of the factors influencing cervical spine surgery outcomes based on citespace.
  30. Application of piezoelectric materials in the field of bone: a bibliometric analysis.
  31. Comment on: Bibliometric analysis of glaucoma-related literature based on SCIE database: a 10-year literature analysis from 2009 to 2018.
  32. Current Status and Trends in mHealth-Based Research for Treatment and Intervention in Tinnitus: Bibliometric and Comparative Product Analysis.
  33. The intersection of COVID-19 and air pollution: A systematic literature network analysis and roadmap for future research.
  34. Food Composition Databases (FCDBs): A Bibliometric Analysis.
  35. Medical applications of generative adversarial network: a visualization analysis.
  36. Exploring New Therapeutic Avenues for Ophthalmic Disorders: Glaucoma-Related Molecular Docking Evaluation and Bibliometric Analysis for Improved Management of Ocular Diseases.
  37. Navigating the landscape of Rho GTPase signalling system in autoimmunity: A bibliometric analysis spanning over three decades (1990 to 2023).
  38. Virtual Reality Technology in Nursing Professional Skills Training: Bibliometric Analysis.
  39. The Role of Ultrasound in Cancer and Cancer-Related Pain-A Bibliometric Analysis and Future Perspectives.
  40. Omernik's Ecoregion Framework: a Legacy for Understanding Regional Patterns in Attainable Resource Quality.
  41. Correction to: Citation context.
  42. The positive impact on translational research of Fondazione italiana di ricerca per la Sclerosi Laterale Amiotrofica (AriSLA), a non-profit foundation focused on amyotrophic lateral sclerosis. Convergence of ex-ante evaluation and ex-post outcomes when goals are set upfront.
  43. Probiotics and biofilm interaction in aquaculture for sustainable food security: A review and bibliometric analysis.
  44. Machine learning models can predict subsequent publication of North American Spine Society (NASS) annual general meeting abstracts.
  45. Incidence of periprosthetic joint infection after primary total hip arthroplasty is underestimated: a synthesis of meta-analysis and bibliometric analysis.
  46. Medical Applications of Artificial Intelligence and Large Language Models: Bibliometric Analysis and Stern Call for Improved Publishing Practices.
  47. Artificial Intelligence and Machine Learning in Cancer Research: A Systematic and Thematic Analysis of the Top 100 Cited Articles Indexed in Scopus Database.
  48. Adipose Tissue-Derived Stem Cells in Plastic and Reconstructive Surgery: A Bibliometric Study.
  49. Trauma and Critical Care Military-Civilian Publications Increased After the COVID-19 Pandemic: A Literature Review.
  50. Fermented foods and beverages: a potential in situ vitamin B12 biofortification - a literature review.
  51. Xylooligosaccharides: A Bibliometric Analysis and Current Advances of This Bioactive Food Chemical as a Potential Product in Biorefineries' Portfolios.
  52. Comparison of the rate of change (slopes) in impact factor of medical imaging journals unveils journals with organic growth: An observational study (2016-2022).
  1. Obes Facts. 2023 Aug 18.
    Bibliometric and correlation analysis of bariatric surgery researches in Asia-Pacific from 2000 to 2021.
    Guanhua Lu, Ruixiang Hu, Zhiyong Dong, Jianxue Wang, Wah Yang, Cunchuan Wang.
       INTRODUCTION: Bariatric surgery has grown in popularity over the past two decades, especially in the Asia-Pacific. Correspondingly, researchers' interest in this field has also increased. This study aims to perform a bibliometric analysis of publications from Asia-Pacific represented by the International Federation for the Surgery of Obesity and Metabolic Disorders Asia-Pacific Chapter (IFSO-APC) and investigate the relevant factors that might affect the publications.
    METHODS: The search terms for bariatric surgery were searched in Web of Science focusing on the period 2000-2021. Bibliometric analysis was performed after screening the search results. Univariate and multivariate regression analyses were performed on the number of publications and corresponding indicators obtained from official agencies.
    RESULTS: A total of 9547 publications in IFSO-APC were retrieved, of which China had the largest number with 2782 publications. Authors and journals with major contributions were listed. The authors' or affiliations' cooperation networks mainly were limited to domestic. "Bariatric surgery" was the most frequent keyword with 2063 times and also the largest cluster. "Morbid obesity" was the strongest citation bursts. Multivariate analysis found that the number of publications in each country/region was associated with body mass index≥25 kg/m2, gross domestic product, and total population.
    CONCLUSION: Generally, Asia-Pacific represented by IFSO-APC scientific publications on bariatric surgery has grown significantly in the last two decades, but cooperation between countries/regions should be strengthened. "Morbid obesity" is the focus and frontier of research in this field.
    DOI:  https://doi.org/10.1159/000533152
  2. J Pain Res. 2023 ;16 2817-2834
    Global Trends and Hotspots on Microglia Associated with Pain from 2002 to 2022: A Bibliometric Analysis.
    Guoqi Dong, Hui Li, Hui Gao, Yingqi Chen, Huayuan Yang.
       Background: Researchers have made significant progress in microglia associated with pain in recent years. However, more relevant bibliometric analyses are still needed on trends and directions in this field. The aim of this study is to provide a comprehensive perspective and to predict future directions of pain-related microglia research via bibliometric tools.
    Methods: English articles and reviews related with pain and microglia were extracted from the Web of Science core collection (WosCC) database between 2002 to 2022. Bibliometric tools such as VOSviewer, CiteSpace, and Bibliometrix R package were used to analyze publication characteristics, countries, authors, institutions, journals, research hotspots, and trend topics.
    Results: A total of 2761 articles were included in this analysis. Research on microglia associated with pain has increased significantly over the last two decades. China (n = 1020, 36.94%) and the United States (n = 751, 27.20%) contributed the most in terms of publications and citations, respectively. Kyushu University published the most articles in this field compared to other institutions, and Professor Inoue Kazuhide (n = 54) at this university made outstanding contributions in this field. Molecular Pain (n = 113) was the journal with the most publication, while Journal of Neuroscience had the highest number of citations. According to the authors keywords analysis, the research in this area can be summarized into 7 clusters such as "microglia activation pathways", "pain treatment research", "mental symptoms of chronic pain", and so on.
    Conclusion: This study provides a comprehensive analysis of pain-related microglia research in the past two decades. We identified the countries, institutions, scholars, and journals with the highest number of publications and the most influence in the field, and the research trends identified in this paper may provide new insights for future research.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; microglia; pain
    DOI:  https://doi.org/10.2147/JPR.S413028
  3. Heliyon. 2023 Aug;9(8): e18950
    Trends and hotspots of publications on ferroptosis: A 10 Year overview.
    Bingzhou Ji, Guang Yang, Hongfu Jin, Xu Liu, Hengzhen Li, Linyuan Pan, Wenhao Lu, Heyuan Zhu, Yusheng Li.
       Background: Ferroptosis was proposed to be a type of programmed cell death in 2012. Ferroptosis plays a significant role in a variety of illnesses.
    Objective: To better understand the direction of future research, we performed a bibliometric analysis to identify research hotspots with a focus on ferroptosis.
    Methods: The search terms [TI = "ferroptosis" OR ("GSH" AND "GPX4") OR "lipid peroxidation" OR "iron homeostasis" OR "iron metabolism"] AND [PY = "2012-2022"] AND [DT = "Article OR Review"] AND [LA = "English"] were used to retrieve publications related to ferroptosis for a bibliometric analysis. We utilized Microsoft Excel to calculate the frequency and proportion of the published articles, VOSviewer to perform a co-occurrence analysis and for visualizing the data, CiteSpace to obtain a timeline of keywords and institutions, and RStudio to calculate citation metrics. As indicated by the analysis, indicators such as the number of publications, the most productive authors and coauthorship status, the distribution of publications by country, favoured journals, the most influential institutions and the most frequently cited documents are reported in this article.
    Results: A total of 8009 publications were retrieved from the WOS core collection, and 197 papers published in 2023 were removed from this analysis. The remaining 7812 papers, which included 118 in the WOS collection, were incorporated into the bibliometric study.
    Conclusion: The number of annual scientific publications on ferroptosis have been increasing each year. The academic communities represented by Tang, Daolin, Stockwell, Brent R., Wang, Fudi, and Conrad, Marcus were the most authoritative. China, USA, and Germany were the front-runners in the field of ferroptosis. Free Radical Biology and Medicine was the largest contributor of ferroptosis-related research, and Cell and Nature were the most influential journals to publish articles on ferroptosis. Columbia Univ and Univ Pittsburgh were the institutions that received the most attention. Recent research on ferroptosis has been focused on molecular mechanisms, particularly those in the contexts of various diseases, which will be a hotspot of future research. In addition, interdisciplinary ferroptosis and big-data research is expected to be a new frontier.
    Keywords:  Bibliometric analysis; CiteSpace; Ferroptosis; RStudio; VOSviewer
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e18950
  4. Medicine (Baltimore). 2023 Aug 18. 102(33): e34807
    Bibliometric analysis of the 100 most cited articles in nonspecific neck pain research: A STROBE-compliant study.
    Yu Kondo, Yuzo Ashida, Yuki Nomura, Takahiro Miki, Yuta Watanabe, Tsuneo Takebayashi.
      The purpose of this study was to identify and analyze the top 100 cited articles in nonspecific neck pain (NSNP) research. A set of search terms was entered into the Web of Science database, and the articles with the highest citation counts in the field of NSNP were chosen. The top 100 articles were examined for total citation count, annual citations count, first author, year of publication, journal, study design, and country of origin. The citation count for the list final articles ranged from 181 to 2067, with an average of 291.9. The journal Spine contributed the most articles (25), followed by pain (16). Between 2001 and 2010, the most prolific years, 66 articles were published. In terms of country of origin, the majority of articles were from Australia (22). Vernon H., published the most cited article in the Journal of Manipulative & Physiological Therapeutics in 1991, reporting the first instrument developed to assess self-reported disability in patients with neck pain. The bibliographic analysis to identify the top 100 most cited articles related to NSNP acknowledges the field historical advances and provides insight into the types of articles that have provided these advances.
    DOI:  https://doi.org/10.1097/MD.0000000000034807
  5. J Pain Res. 2023 ;16 2847-2860
    Bibliometric Analysis of Research on Temporomandibular Joint and Occlusion from 2000 to 2022.
    Xin Xiong, Xinlin Gao, Jiawei Zhong, Shoushan Hu, Yijun Li, Yunhao Zheng, Yang Liu.
       Purpose: This study conducted a bibliometric analysis that comprehensively described publications on temporomandibular joint and occlusion from 1 January 2000 to 31 October 2022, aiming to reveal hotspots and predict future research trends.
    Methods: A total of 2985 articles and reviews were retrieved from Web of Science Core Collection (WoSCC). Excel 2019, VOSviewer and CiteSpace software were used for visualizing analysis of research trends, authors, journals, institutions, countries, keywords and cited references.
    Results: Both the annual publication counts and citation times increased significantly. Wang MQ was the most active author. Moreover, Manfredini D and Okeson JP were the most influential two. Journal of Oral Rehabilitation was the core journal. University of Sao Paulo was the most productive institutions. "Temporomandibular disorders" (TMDs), "temporomandibular joint" and "occlusion" were the top 3 keywords with the most frequencies. Keywords and references with burst showed that the causes of TMDs, diagnosis and treatments for TMDs as well as bruxism may be hotspots currently and in the future.
    Conclusion: In this study, the research trends, the most productive and influential authors, journals, institutions, countries, in addition to keywords and cited references with burst in the field of temporomandibular joint and occlusion were revealed by a bibliometric analysis, which could help scholars to understand recent hotspots and future trends.
    Keywords:  bibliometric analysis; keywords analysis; occlusion; temporomandibular joint
    DOI:  https://doi.org/10.2147/JPR.S418362
  6. Endocr Metab Immune Disord Drug Targets. 2023 Aug 22.
    Thyroid Nodules: Emerging trends in Detection and Visualization based on Citespace.
    Wenyan Yao, Yunhui Guan, Xiujuan Peng, Xia Du, Conglong Xia, Feng Liu.
       BACKGROUND: Thyroid nodule (TN) is a highly prevalent clinical endocrine disease. Many countries have formed guidelines on the prevention and treatment of TNs based on extensive research. However, there is a scarcity of TN-related literature based on bibliometrics.
    OBJECTIVE: This study aimed to evaluate the scientific achievements and progress of TN research from a global perspective by investigating the literature for 20 years through bibliometrics.
    METHODS: We searched the literature on TN in the core collection of the Web of Science database from 2002 to 2021 and used the Citespace software to analyze the co-authorship, co-citation, and co-occurrence of countries, institutions, authors, keywords, and co-cited literature.
    RESULTS: We retrieved 12319 documents related to TNs. The literature on TN has been growing since 2002. The United States has contributed the largest proportion of TN papers (20.64%), followed by China, Italy, and South Korea. The United States ranked first in terms of centrality (0.38). Haugen BR, Gharib H, and Cibas ES are the top three most cited authors. The papers published in Thyroid were cited most frequently (7952 times). The most prominent keywords were management, cancer, fine needle aspiration, diagnosis, malignant tumor, thyroid cancer, ultrasound, biopsy, benign, surgery, ablation, and cytology. All keywords could be divided into three categories: diagnosis stratification, treatment, and cancer. As far as potential hot spots are concerned, the keywords that have recently burst strongly and are still continuing are: "Association Guideline" (2018-2021), "Radiofrequency Ablation" (2017-2021), "Classification" (2019-2021), and "Data System" (2017-2021).
    CONCLUSION: Based on the current trends, the number of publications on TN will continue to increase. The United States is the most active contributor to research in this field. Previous literature focused on stratification, cancer, surgery, and ablation, and there were different opinions on the stratification of diagnosis. There were relatively few studies on pathogenesis and treatment using medicine. More focus will be placed on association guidelines, radiofrequency ablation, classification, and data system, which may be the next popular topics in TNs research.
    Keywords:  Citespace; Thyroid nodules; WoSCC; bibliometric analysis; citation; hotspot
    DOI:  https://doi.org/10.2174/1871530323666230822143549
  7. Environ Sci Pollut Res Int. 2023 Aug 23.
    Thirty years of research on photoacoustic imaging in the field of cancer: A scientometric analysis of hotspots, bursts, and research trends.
    Zhifan Li, Ya Gao, Jinhui Tian, Qihua Song, Mingyuan Wang, Junqiang Lei.
      As a novel imaging modality based on photoacoustic effects, photoacoustic imaging (PAI) has shown great potential in biomedical applications, especially in the field of cancer. The purpose of our research was to identify collaborations between different institutions, authors, and countries, and to explore the hotspots and prospects of PAI research in the field of cancer. We downloaded publications on PAI research from the Science Citation Index-Expanded (SCI-E) of the Web of Science Core Collection database. Bibliometric analysis was performed using VOSviewer and CiteSpace software. A total of 2561 papers related to PAI research in the field of cancer were identified. A total of 10,105 authors participated in the PAI study, of which the majority (69.33%) authors participated in only 1 article. China (1638, 63.96%) was the country with the most articles in this field, and the Chinese Academy of Sciences (329, 12.85%) was the most productive institution. ACS Applied Materials & Interfaces (146, 5.70%) was the most productive journal and ACS Nano (7262 co-citations) was the most co-cited journal. Current hot topics of PAI research in the cancer field were the construction and development of multifunctional photoacoustic nanoprobes to achieve the integration of tumor detection and treatment. The application of photoacoustic imaging in the field of cancer is in the vigorous development stage and has a bright prospect. There was a wealth of cooperation between authors, countries, and institutions. Our findings can provide information about the future direction of funding agencies and research groups.
    Keywords:  Bibliometric analysis; Cancer; Development trends; Hot topics; Photoacoustic; VOSviewer
    DOI:  https://doi.org/10.1007/s11356-023-29243-9
  8. Head Face Med. 2023 Aug 23. 19(1): 38
    Artificial intelligence in orthodontics and orthognathic surgery: a bibliometric analysis of the 100 most-cited articles.
    Ka Fai Wong, Xiang Yao Lam, Yuhao Jiang, Andy Wai Kan Yeung, Yifan Lin.
       BACKGROUND: The application of artificial intelligence (AI) in orthodontics and orthognathic surgery has gained significant attention in recent years. However, there is a lack of bibliometric reports that analyze the academic literature in this field to identify publishing and citation trends. By conducting an analysis of the top 100 most-cited articles on AI in orthodontics and orthognathic surgery, we aim to unveil popular research topics, key authors, institutions, countries, and journals in this area.
    METHODS: A comprehensive search was conducted in the Web of Science (WOS) electronic database to identify the top 100 most-cited articles on AI in orthodontics and orthognathic surgery. Publication and citation data were obtained and further analyzed and visualized using R Biblioshiny. The key domains of the 100 articles were also identified.
    RESULTS: The top 100 most-cited articles were published between 2005 and 2022, contributed by 458 authors, with an average citation count of 22.09. South Korea emerged as the leading contributor with the highest number of publications (28) and citations (595), followed by China (16, 373), and the United States (7, 248). Notably, six South Korean authors ranked among the top 10 contributors, and three South Korean institutions were listed as the most productive. International collaborations were predominantly observed between the United States, China, and South Korea. The main domains of the articles focused on automated imaging assessment (42%), aiding diagnosis and treatment planning (34%), and the assessment of growth and development (10%). Besides, a positive correlation was observed between the testing sample size and citation counts (P = 0.010), as well as between the time of publication and citation counts (P < 0.001).
    CONCLUSIONS: The utilization of AI in orthodontics and orthognathic surgery has shown remarkable progress, particularly in the domains of imaging analysis, diagnosis and treatment planning, and growth and development assessment. This bibliometric analysis provides valuable insights into the top-cited articles and the trends of AI research in this field.
    Keywords:  Artificial intelligence; Bibliometrics; Orthodontics and orthognathic surgery
    DOI:  https://doi.org/10.1186/s13005-023-00383-0
  9. Clin Rheumatol. 2023 Aug 24.
    Bibliometric analysis of the global publication activity in the field of relapsing polychondritis during 1960-2023.
    Linlin Cheng, Yongmei Liu, Qingqing Ma, Songxin Yan, Haolong Li, Haoting Zhan, Zhan Li, Yongzhe Li.
       BACKGROUND: Relapsing polychondritis (RP) is an inflammatory disease with significant individual heterogeneity that involves systemic cartilage tissues. This study aimed to perform a bibliometric analysis of RP-related publications to quantitatively assess the scholarly productivity in the field.
    METHODS: We extracted the RP-related original research articles and reviews published during 1960-2023 from the Web of Science database by using the keyword "relapsing polychondritis." By using R, CiteSpace, VOSviewer, and SCImago Graphica, the bibliometric analysis was performed on the retrieved publications.
    RESULTS: A total of 1096 articles, consisting of 909 original research articles and 187 reviews, were identified. A mean annual growth rate of 6.71% was found in the number of RP-related publications during 1960-2022. The United States accounted for the highest number of publications (21.9%), exhibited the highest mean citation number per publication (40.7), and engaged in the most frequent academic collaboration. Three clusters of RP-related journals were identified: 1) otology, rhinology, and laryngology; 2) respiratory and radiology medicine; and 3) rheumatology. Journals with a focus on rheumatology issued the most publications, and most of the RP-related publications were from The Journal of Rheumatology (n = 27). Most of these publications were co-authored by Dr. Jean-Charles Piette (n = 19), who also had the highest H-index (13) among all the authors. The co-citation network analysis revealed 11 highly connected clusters of RP research and indicated the "VEXAS Syndrome" as a hotspot.
    CONCLUSION: This overview of the RP research field comprehensively describes the progress in the field. The number of publications on RP has progressively increased but remains insufficient. The United States and European countries are at the forefront of RP-related research, and the journals related to rheumatology have covered the majority of publications. Additionally, several key topics for future investigations, such as "VEXAS Syndrome," have been identified. Key Points •We identified a mean annual growth rate of 6.71% in the number of the RP-related publications during 1960-2022. •The United States accounted for the majority of the publications, exhibited the highest mean citation number per publication, and engaged in the most frequent academic collaborations. •The journals of the publications were categorized into three clusters of research areas: 1) otology, rhinology, and laryngology; 2) respiratory and radiology medicine; and 3) rheumatology. Journals related to rheumatology issued the most publications, and most of the publications were from The Journal of Rheumatology •Most of the publications were co-authored by Dr. Jean-Charles Piette, who also had the highest scientific-research impact among the scholars in the field. •The co-citation network analysis revealed 11 highly connected clusters of RP research and indicated the "VEXAS Syndrome" as a key research area.
    Keywords:  Bibliometric analysis; Relapsing polychondritis; VEXAS Syndrome; Web of Science
    DOI:  https://doi.org/10.1007/s10067-023-06741-2
  10. Microorganisms. 2023 Aug 21. pii: 2125. [Epub ahead of print]11(8):
    Bibliometric Analysis of Global Trends in Research on Seasonal Variations in Gut Microbiota from 2012 to 2022.
    Jiancheng Zhai, Xiao Sun, Rui Lu, Xueqin Hu, Zhiqiang Huang.
      Seasons are the important influencing factor for gut microbiota, which in turn affects the ecology and evolution of the host. The seasonal variation in gut microbiota has increasingly attracted the attention of researchers and professionals worldwide. However, studies of seasonal variations in gut microbiota have not been systematically analyzed by bibliometrics or visual analysis. This study is based on 271 publications from 2012 to 2022 in the Web of Science Core Collection database (WOSCC) to analyze hot spots and trends in this field. The collaborations between different countries, institutions, authors, journals, and keywords were bibliometrically analyzed using Excel, CiteSpace (Version 6.2. R4), and VOSviewer (version 1.6.19) software. The number of publications has been increasing rapidly and shows a general upward trend. China and the Chinese Academy of Sciences are the country and institution contributing the most, respectively. The research hotspots and trends mainly include the diversity of gut microbiota communities in different seasons, the relationship between diet and gut microbiota in seasonal changes, and the relationship between gut microbiota and evolutionary adaptation in seasonal changes. This is the first bibliometric and visualization analysis of seasonal variations in gut microbiota, which may advance this field and lay the foundation for future research.
    Keywords:  CiteSpace; bibliometric analysis; gut microbiota; seasonal; visualization
    DOI:  https://doi.org/10.3390/microorganisms11082125
  11. Environ Sci Pollut Res Int. 2023 Aug 19.
    Mapping scientific knowledge discovery on COVID-19 pandemic and agriculture: a bibliometric analysis and future research directions.
    Jabir Ali.
      This paper aims at analyzing the research productivity and scientific knowledge discovery of the COVID-19 pandemic in agriculture using a bibliometric analysis approach. A total of 1514 research papers indexed in the Scopus database, covering a period of 2020 to 2022, are processed using VOSviewer and R-Studio software. The analysis of research productivity indicates that the number of research publications on COVID-19 and agriculture has exponentially increased globally, and about 80% of the research papers have been published in the top 10 countries led by the USA, India, and China. The countries are increasingly collaborating in undertaking research on COVID-19 and agriculture. Furthermore, major journals and articles with citations have been extracted to analyze the leading publication avenues and focused areas of research. The science mapping is done using co-occurrence and thematic map. With the help of co-occurrence analysis, six clusters are identified depicting major research themes, i.e., COVID-19 and agricultural supply chain disruption, COVID-19 and human health issues and coping strategies, COVID-19 and non-human and animal health, COVID-19 pandemic and environment and pollution, COVID-19 and healthcare and treatment, and COVID-19 and food nutrition from dairy and meat products. The thematic map analysis identifies potential research areas such as mental health, anxiety, and depression in the agricultural system, which may help in setting future research agenda and help devising policy supports for managing the agriculture sector better during crisis. The paper also highlights the theoretical and practical implications.
    Keywords:  Agricultural decisions; Bibliometric analysis; COVID-19 pandemic; Future research direction
    DOI:  https://doi.org/10.1007/s11356-023-29238-6
  12. Medicine (Baltimore). 2023 Aug 18. 102(33): e34831
    A bibliometric systematic review of extracellular vesicles in eye diseases from 2003 to 2022.
    Xianke Luo, Xiaoling Yan, Dan Yin, Yanting Xia, Shimeng Li, Suisui Shi, Miaoran Gao, Changlu Yang, Jian Zhou.
       BACKGROUND: Extracellular vesicles (EVs) have emerged as a valuable and promising research field in eye diseases. However, there are few bibliometric studies in this area. The purpose of this study was to employ bibliometric analysis to visualize the research hotspots and trends of EVs in eye diseases and provide researchers with new perspectives for further studies.
    METHODS: Articles and reviews on EVs in eye diseases published between January 1, 2003 and December 31, 2022 were retrieved from the Web of Science Core Collection. Qualitative and quantitative analysis was performed using Microsoft Excel and CiteSpace software.
    RESULTS: In total, 790 articles were included in the analysis. Over the past 2 decades, there has been a significant increase in the number of publications on the study of EVs in eye diseases. The United States, China, and Italy made the most significant contributions to this field. The Chinese Academy of Sciences was the most productive institution, and International Journal of Molecular Sciences published the most number of articles. Proceedings of the National Academy of Sciences of the United States of America had the highest citation frequency. Beit-Yannai E had the highest output and Thery C had the highest average citation frequency among authors. The analysis of keywords revealed that the neuroprotective effects of stem cell-derived EVs and biomarkers of eye diseases are current research hotspots and frontiers in this field.
    CONCLUSION: This study provides a scientific perspective on EVs in eye diseases and provides valuable information for researchers to detect current research conditions, hotspots, and emerging trends for further study.
    DOI:  https://doi.org/10.1097/MD.0000000000034831
  13. Front Cell Infect Microbiol. 2023 ;13 1225859
    Gut microbiota and eye diseases: a bibliometric study and visualization analysis.
    Xiangyu Fu, Haishan Tan, Ling Huang, Wenyue Chen, Xiang Ren, Danian Chen.
       Introduction: Recently the role of gut microbial dysbiosis in many ocular disorders, including but not limited to uveitis, age-related macular degeneration (AMD), diabetic retinopathy (DR), dry eye, keratitis and orbitopathy is a hot research topic in the field. Targeting gut microbiota to treat these diseases has become an unstoppable trend. Bibliometric study and visualization analysis have become essential methods for literature analysis in the medical research field. We aim to depict this area's research hotspots and future directions by bibliometric software and methods.
    Methods: We search all the related publications from the Web of Science Core Collection. Then, CiteSpace was applied to analyze and visualize the country distributions, dual-map overlay of journals, keyword bursts, and co-cited references. VOSviewer was employed to identify authors, co-cited authors, journals and co-cited journals and display the keyword co-occurrence networks.
    Results: A total of 284 relevant publications were identified from 2009 to 2023. The number of studies has been small in the first five years and has grown steadily since 2016. These studies were completed by 1,376 authors from 41 countries worldwide, with the United States in the lead. Lin P has published the most papers while Horai R is the most co-cited author. The top journal and co-cited journal are both Investigative Ophthalmology & Visual Science. In the keyword co-occurrence network, except gut microbiota, inflammation becomes the keyword with the highest frequency. Co-citation analyses reveal that gut dysbiosis is involved in common immune- and inflammation-mediated eye diseases, including uveitis, diabetic retinopathy, age-related macular degeneration, dry eye, and Graves' orbitopathy, and the study of microbiomes is no longer limited to the bacterial populations. Therapeutic strategies that target the gut microbiota, such as probiotics, healthy diet patterns, and fecal microbial transplantation, are effective and critical to future research.
    Conclusions: In conclusion, the bibliometric analysis displays the research hotspots and developmental directions of the involvement of gut microbiota in the pathogenesis and treatment of some ocular diseases. It provides an overview of this field's dynamic evolution and structural relationships.
    Keywords:  CiteSpace; VOSviewer; bibliometric study; eye disease; fecal microbial transplantation; gut microbiota; inflammation; probiotics
    DOI:  https://doi.org/10.3389/fcimb.2023.1225859
  14. Front Immunol. 2023 ;14 1210802
    Bibliometric study of immunotherapy for hepatocellular carcinoma.
    Zhiyi Li, Ying Zhang, Baipan Zhang, Rui Guo, Minhua He, Zi-Ling Liu, Lei Yang, Hong Wang.
       Background: Hepatocellular carcinoma (HCC), recognized as a significant global health concern, ranks as the sixth most prevalent form of cancer and is the third leading cause of cancer-associated mortality. Over half of HCC patients are diagnosed at advanced stages, an unfortunate phenomenon primarily attributed to the liver's robust compensatory mechanisms. Given the limited availability of donor livers, existing clinical surgical approaches have yet to provide universally applicable treatment strategies offering substantial prognostic improvement for late-stage cancer. Although the past few decades have witnessed significant advancements in chemotherapy and targeted therapy for HCC, the emergence of drug resistance poses a substantial impediment to their successful execution. Furthermore, issues such as diminished quality of life post-treatment and high treatment costs warrant critical attention. Consequently, the imperative for an effective treatment strategy for advanced liver cancer is unequivocal. In recent years, notable progress in the development and application of immunotherapy has sparked a revolution in advanced liver cancer treatment. This study aims to elucidate a more comprehensive understanding of the current landscape, knowledge framework, research focal points, and nascent breakthrough trends in the domain of immunotherapy for hepatocellular carcinoma via bibliometric analysis.
    Method: Our study involved conducting a comprehensive literature search spanning from 1999 through December 31, 2022, by utilizing the Science Citation Index Expanded (SCI-Expanded) database. Our aim was to amass all the papers and reviews related to immunotherapy for hepatocellular carcinoma. Our search strategy yielded a total of 4,486 papers. After exclusion of self-citations, we focused our analysis on 68,925 references. These references were cited 119,523 times (excluding 97,941 self-citations), boasting an average citation frequency of 26.64 times per paper, and achieved an h-index of 135. We employed analytical software tools like Citespace and VOSviewer to perform an intricate analysis of the amassed literature, covering various aspects, including geographical location, research institutions, publishing journals, authors, references, and keywords. Our method incorporated timeline analysis, burst detection, and co-occurrence analysis. The application of these tools facilitated a thorough evaluation of research hotspots, knowledge structure, and emerging advancements within the sphere of immunotherapy for hepatocellular carcinoma.
    Results: Our bibliometric analysis disclosed a noteworthy escalation in the number of publications in the realm of hepatocellular carcinoma immunotherapy during the years 2021-2022, surpassing the aggregate number of papers published in the preceding decade (2011-2020). This surge underscores a sharp upturn in research interest within this field. Additionally, the research hotspot in hepatocellular carcinoma immunotherapy has perceptibly deviated from the preceding decade's trends. In terms of geographical distribution, China emerged as the leading country, producing 50.08% of the total publications. This was followed by the United States, with 963 papers, and Japan, contributing 335 papers. Among research institutions, Sun Yat-sen University was the most prolific, while Tim F. Greten stood out as the most published author with 42 papers to his credit. A co-reference network examination uncovered a shift in research emphasis within the field of hepatocellular carcinoma immunotherapy, highlighting the evolving nature of this important area of study.
    Conclusion: Our bibliometric study highlights the significant evolution and growth in HCC immunotherapy research over the past two decades. Looking ahead, research will focus on improving the microenvironment post-drug resistance from immune combination therapy, harnessing adoptive cellular immunity (as CAR-T), subclassify the population and developing new tumor markers. Incorporation of technologies such as nanotechnology, microbiology, and gene editing will further advance HCC treatments. This progressive trajectory in the field promises a brighter future for individuals suffering from HCC.
    Keywords:  Citespace; HCC; VOSviewer; bibliometric; hepatocellular carcinoma; immunotherapy; liver cancer
    DOI:  https://doi.org/10.3389/fimmu.2023.1210802
  15. Front Cell Infect Microbiol. 2023 ;13 1112229
    The application of metagenomic next-generation sequencing in pathogen diagnosis: a bibliometric analysis based on Web of Science.
    Sike He, Jingwen Wei, Jiaming Feng, Dan Liu, Neng Wang, Liyu Chen, Ying Xiong.
       Background: Infectious disease is a large burden on public health globally. Metagenomic next-generation sequencing (mNGS) has become popular as a new tool for pathogen diagnosis with numerous advantages compared to conventional methods. Recently, research on mNGS increases yearly. However, no bibliometric analysis has systematically presented the full spectrum of this research field. Therefore, we reviewed all the publications associated with this topic and performed this study to analyze the comprehensive status and future hotspots of mNGS for infectious disease diagnosis.
    Methods: The literature was searched in the Web of Science Core Collection and screened without year or language restrictions, and the characteristics of the studies were also identified. The outcomes included publication years, study types, journals, countries, authorship, institutions, frontiers, and hotspots with trends. Statistical analysis and visualization were conducted using VOSviewer (version 1.6.16) and CiteSpace (version 6.1. R3).
    Results: In total, 325 studies were included in the analysis after screening. Studies were published between 2009 and 2022 with a significantly increasing number from 1 to 118. Most of the studies were original articles and case reports. Frontiers in Cellular and Infection Microbiology and Clinical Infectious Disease were the most commonly cited and co-cited journals. Institutions and researchers from China contributed the most to this field, followed by those from the USA. The hotspots and frontiers of these studies are pneumonia, tuberculosis, and central nervous system infections.
    Conclusion: This study determined that mNGS is a hot topic in the diagnosis of infectious diseases with development trends and provides insights into researchers, institutions, hotspots and frontiers in mNGS, which can offer references to related researchers and future research.
    Keywords:  CiteSpace; VOSviewer; Web of Science; bibliometric analysis; metagenomic next-generation sequencing; pathogen diagnosis
    DOI:  https://doi.org/10.3389/fcimb.2023.1112229
  16. Heliyon. 2023 Aug;9(8): e18942
    Stakeholder governance and sustainability in football: A bibliometric analysis.
    Juan Alejandro Hernández-Hernández, Abraham Londoño-Pineda, Jose Alejandro Cano, Rodrigo Gómez-Montoya.
      This study presents a bibliometric analysis of stakeholder governance and sustainability in football. The PRISMA statement and the main techniques from the existing bibliometric analysis toolbox are applied to guide the research. The analysis includes 127 documents from Scopus and WoS, covering the period from 2007 to mid-2023, to examine the performance analysis and science mapping of the subject over time. The study's key findings highlight publication-related metrics, citation-and-publication-related metrics, co-authorship analysis, and co-word analysis. The analysis also identifies research gaps, including the need to explore barriers to stakeholder governance in football, the application of stakeholder pressure frameworks in football clubs, the examination of mimetic and normative pressures in the context of sustainability and governance in football, and the involvement of stakeholders and football institutions in collaborative efforts to enhance the effectiveness and impact of sustainability initiatives.
    Keywords:  Bibliometric analysis; Football; Soccer; Stakeholder governance; Sustainability; Systematic review
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e18942
  17. J Nanobiotechnology. 2023 Aug 23. 21(1): 289
    A swift expanding trend of extracellular vesicles in spinal cord injury research: a bibliometric analysis.
    Fan Zhiguo, Wu Ji, Chen Shenyuan, Zhang Guoyou, Kai Chen, Qian Hui, Xu Wenrong, Xiao Zhai.
      Extracellular vesicles (EVs) in the field of spinal cord injury (SCI) have garnered significant attention for their potential applications in diagnosis and therapy. However, no bibliometric assessment has been conducted to evaluate the scientific progress in this area. A search of articles in Web of Science (WoS) from January 1, 1991, to May 1, 2023, yielded 359 papers that were analyzed using various online analysis tools. These articles have been cited 10,842 times with 30.2 times per paper. The number of publications experienced explosive growth starting in 2015. China and the United States led this research initiative. Keywords were divided into 3 clusters, including "Pathophysiology of SCI", "Bioactive components of EVs", and "Therapeutic effects of EVs in SCI". By integrating the average appearing year (AAY) of keywords in VoSviewer with the time zone map of the Citation Explosion in CiteSpace, the focal point of research has undergone a transformative shift. The emphasis has moved away from pathophysiological factors such as "axon", "vesicle", and "glial cell" to more mechanistic and applied domains such as "activation", "pathways", "hydrogels" and "therapy". In conclusions, institutions are expected to allocate more resources towards EVs-loaded hydrogel therapy and the utilization of innovative materials for injury mitigation.
    Keywords:  Bibliometric; Citation; Extracellular vesicles; H-index; Hotspots; Spinal cord injury
    DOI:  https://doi.org/10.1186/s12951-023-02051-6
  18. Bioengineering (Basel). 2023 Aug 04. pii: 929. [Epub ahead of print]10(8):
    Research Hotspots and Trends of Bone Xenograft in Clinical Procedures: A Bibliometric and Visual Analysis of the Past Decade.
    Jiayue Li, Yujue Zhao, Shili Chen, Simin Wang, Wen Zhong, Qing Zhang.
       BACKGROUND: Bone defect therapy is a common clinical challenge for orthopedic and clinical physicians worldwide, and the therapeutic effect affects the physiological function and healthy life quality of millions of patients. Compared with traditional autogenous bone transplants, bone xenografts are attracting attention due to their advantages of unlimited availability and avoidance of secondary damage. However, there is currently a lack of bibliometric analysis on bone xenograft. This study aimed to use bibliometric methods to analyze the literature on bone xenograft from 2013 to 2023, to explore the current status, hotspots, and future trends of research in this field, and to promote its development and progress.
    METHODS: Using the Web of Science Core Collection database, we retrieved and collected publication data related to xenogeneic bone grafting materials worldwide from January 2013 to March 2023. Origin (2021), CiteSpace (6.2.R2 standard), and an online bibliometric platform were used for bibliometric analysis and data visualization.
    RESULTS: A total of 3395 documents were retrieved, and 686 eligible papers were selected. The country and institutions with the highest number of publications and centrality were the United States (125 papers, centrality = 0.44) and the University of Zurich (29 papers, centrality = 0.28), respectively. The most cited author was Araujo MG (163 times), and the author with the most significant centrality was Froum SJ (centrality = 0.09). The main keyword clusters were "tissue engineering", "sinus floor elevation", "dental implants", "tooth extraction", and "bone substitutes". The most significant bursting keywords in the last three years were "platelet rich fibrin".
    CONCLUSIONS: Research on bone xenograft is steadily growing and will continue to rise. Currently, research hotspots and directions are mainly focused on dental implants related to bone-augmentation techniques and bone tissue engineering. In the future, research hotspots and directions may focus on decellularization technology and investigations involving platelet-rich fibrin.
    Keywords:  CiteSpace; bibliometric analysis; bone defects; bone xenograft; research hotspots
    DOI:  https://doi.org/10.3390/bioengineering10080929
  19. Glob Health Epidemiol Genom. 2023 ;2023 8856736
    Global Trend on Machine Learning in Helicobacter within One Decade: A Scientometric Study.
    Omid Eslami, Mohsen Nakhaie, Mohammad Rezaei Zadeh Rukerd, Maryam Azimi, Ellahe Shahabi, Amin Honarmand, Mahdiyeh Khazaneha.
       Purpose: This study aims to create a science map, provide structural analysis, investigate evolution, and identify new trends in Helicobacter pylori (H. pylori) research articles.
    Methods: All Helicobacter publications were gathered from the Web of Science (WoS) database from August 2010 to 2021. The data were required for bibliometric analysis. The bibliometric analysis was performed with Bibliometrix R Tool. Bibliometric data were analyzed using the Bibliometrix Biblioshiny R-package software.
    Results: A total of 17,413 articles were reviewed and analyzed, with descriptive characteristics of the H. pylori literature included. In journals, 21,102 keywords plus and 20,490 author keywords were reported. These articles were also written by 56,106 different authors, with 262 being single-author articles. Most authors' abstracts, titles, and keywords included "Helicobacter-pylori." Since 2010, the total number of H. pylori-related publications has been decreasing. Gut, PLOS ONE, and Gastroenterology are the most influential H. pylori journals, according to source impact. China, the United States, and Japan are the countries with most affiliations and subjects. In addition, Seoul National University has published the most articles about H. pylori. According to the cloud word plot, the authors' most frequently used keywords are gastric cancer (GC), H. pylori, gastritis, eradication, and inflammation. "Helicobacter pylori" and "infection" have the steepest slopes in terms of the upward trend of words used in articles from 2010 to 2021. Subjects such as GC, intestinal metaplasia, epidemiology, peptic ulcer, eradication, and clarithromycin are included in the diagram's motor theme section, according to strategic diagrams. According to the thematic evolution map, topics such as Helicobacter pylori infection, B-cell lymphoma, CagA, Helicobacter pylori, and infection were largely discussed between 2010 and 2015. From 2016 to 2021, the top topics covered included Helicobacter pylori, H. pylori infection, and infection.
    DOI:  https://doi.org/10.1155/2023/8856736
  20. Front Psychiatry. 2023 ;14 1152660
    What we know about grief intervention: a bibliometric analysis.
    Jie Li, Yuan Li, Yali Wang, Wuga Jishi, Jinbo Fang.
       Background: Grief is a natural and individualized response to different losses, but if grief persists or becomes pathological, professional interventions are required. Grief and corresponding interventions have received increasing attention, as the related concepts have been incorporated into the DSM-5 and ICD-11. Therefore, we conducted a bibliometric analysis to explore the developments in the field of grief intervention research.
    Methods: Articles on grief interventions were systematically searched and screened from the Web of Science Core Collection. The retrieved data were analyzed and visualized using VOSviewer and Bibliometrix software for journals, authors, institutions, countries, references, and keywords.
    Results: A total of 9,754 articles were included. The number of articles on grief interventions has increased significantly each year since 1990. Death Studies was the journal that published the most articles in this field. We identified 25,140 authors contributed to this research area and these authors were from 123 countries and 6,630 institutions. Boelen PA secured the first position in article production, Columbia University emerged as the most productive affiliation and the United States was the foremost leading in grief intervention research. The prevalent keywords utilized in this field comprised bereavement, grief, death, depression, and palliative care.
    Conclusion: The quantity of publications regarding grief interventions is increasing. Although most prior studies have focused on mortality, grief, and health, emerging themes such as COVID-19, grief among workers, and disfranchised grief have drawn increasing attention in recent years. Future studies may focus on investigating the complexities and challenges of grief, including its underlying mechanisms and impact on mental well-being.
    Keywords:  VOSviewer; Web of Science; bereavement; bibliometric analysis; grief intervention
    DOI:  https://doi.org/10.3389/fpsyt.2023.1152660
  21. Pathog Glob Health. 2023 Aug 22. 1-8
    Scientific literature on neglected tropical diseases: a bibliometric analysis.
    Gianpiero Tebano, Elisa Vanino, Paolo Muratori, Francesco Cristini.
      Neglected tropical diseases (NTDs) are a group of diseases mainly affecting people in low- and middle-income Countries. The aim of this study was to perform a bibliometric analysis of the scientific literature on NTDs. Using the MeSH database, we quantified the number of publications on MEDLINE targeting each NTD, which were published from 1 January 1999 to 31 January 2019. In order to weight the number of publications targeting a given NTD according to the total number of publications/year, we calculated a Yearly Publication Index (YPI) for each NTD/year. Linear regression was used to determine if there was a significant increase or decrease of YPI over time. In order to weight the number of publications according to disease burden (expressed in Disability-adjusted life years - DALYs) we calculated a DALYs-weighted Publication Index (DWPI) for each NTD. The highest absolute number of publications focused on leishmaniasis, dengue and Chagas disease; the lowest on tungiasis, dracunculiasis, chromoblastomycosis and yaws. The number of publications significantly increased for chikungunya, chromoblastomycosis, dengue, leishmaniasis, snakebite envenoming, and yaws. It significantly decreased for ascariasis, cysticercosis, echinococcosis, leprosy, lymphatic filariasis, mycetoma, onchocerciasis. Leprosy had the highest DWPI (i.e. the highest number of publication considering the burden of disease), followed by Chagas disease; lymphatic filariasis had the lowest, followed by onchocerciasis. Overall, lymphatic filariasis, onchocerciasis and ascariasis presented the worst scenario, with both very few publications compared with their disease burden and a decreasing number of publications.
    Keywords:  Neglected diseases; bibliometric analysis; low- and middle-income countries; research and development; scientific publications
    DOI:  https://doi.org/10.1080/20477724.2023.2250619
  22. Neurosurgery. 2023 Aug 23.
    A Century of Evolution in Spine Surgery Publications: A Bibliometric Analysis of the Field From 1900 to 2023.
    David B Kurland, Alexander T M Cheung, Nora C Kim, Kimberly Ashayeri, Teresa Hidalgo, Anthony Frempong-Boadu, Eric Karl Oermann, Douglas Kondziolka.
       BACKGROUND AND OBJECTIVES: Spine surgery has advanced in concert with our deeper understanding of its elements. Narrowly focused bibliometric analyses have been conducted previously, but never on the entire corpus of the field. Using big data and bibliometrics, we appraised the entire corpus of spine surgery publications to study the evolution of the specialty as a scholarly field since 1900.
    METHODS: We queried Web of Science for all contents from 13 major publications dedicated to spine surgery. We next queried by topic [topic = (spine OR spinal OR vertebrae OR vertebral OR intervertebral OR disc OR disk)]; these results were filtered to include articles published by 49 other publications that were manually determined to contain pertinent articles. Articles, along with their metadata, were exported. Statistical and bibliometric analyses were performed using the Bibliometrix R package and various Python packages.
    RESULTS: Eighty-five thousand five hundred articles from 62 journals and 134 707 unique authors were identified. The annual growth rate of publications was 2.78%, with a surge after 1980, concurrent with the growth of specialized journals. International coauthorship, absent before 1970, increased exponentially with the formation of influential spine study groups. Reference publication year spectroscopy allowed us to identify 200 articles that comprise the historical roots of modern spine surgery and each of its subdisciplines. We mapped the emergence of new topics and saw a recent lexical evolution toward outcomes- and patient-centric terms. Female and minority coauthorship has increased since 1990, but remains low, and disparities across major publications persist.
    CONCLUSION: The field of spine surgery was borne from pioneering individuals who published their findings in a variety of journals. The renaissance of spine surgery has been powered by international collaboration and is increasingly outcomes focused. While spine surgery is gradually becoming more diverse, there is a clear need for further promotion and outreach to under-represented populations.
    DOI:  https://doi.org/10.1227/neu.0000000000002648
  23. J Clin Orthop Trauma. 2023 Aug;43 102232
    Altmetric analysis of the most mentioned articles online in the orthopaedic literature.
    Madison Wood, Parth A Patel, Carter J Boyd.
      Social media has become a valuable tool for the distribution of scientific content. This investigation examined the most mentioned articles in orthopaedics and identified factors concurrent with greater dissemination. Altmetric Attention Score (AAS), which measures the online attention of an article, was examined for 88,683 publications in the top 50 orthopaedic journals by 2021 impact factor. Comparative and correlational analyses were completed. Overall, average AAS and citation count of the 100 most mentioned articles were 606.7 (SD ± 272.0) and 67.55 (SD ± 98.01), respectively. These articles had primarily male first authors (75%), were produced predominantly in the United States (60%), concerned the subspecialty of sports medicine (28%), and were cross-sectional analyses (22%). There were significant differences in AAS between publications (p < 0.05) by the degree of collaboration and the type of article. Such insights can guide authors when considering avenues to increase the impact of their research.
    Keywords:  Altmetrics; Bibliometrics; Open access; Orthopaedics; Social media
    DOI:  https://doi.org/10.1016/j.jcot.2023.102232
  24. Oman J Ophthalmol. 2023 May-Aug;16(2):16(2): 293-297
    Bibliometric analyses of global output on neuromyelitis optica spectrum disorder.
    Carlos Quispe-Vicuña, Miguel Cabanillas-Lazo, Cesar Mauricio-Vilchez, Arnaldo Munive-Degregori, John Barja-Ore, Frank Mayta-Tovalino.
       BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a neuroimmune disease, i.e. under constant research. The aim of this bibliometric study is to perform a bibliometric indicator analysis of the worldwide academic production of NMOSD during the period 2017-2021.
    METHODS: A bibliographic search was assessed in the Scopus database to identify NMOSD-related articles published during the period 2017-2021. Collected publications were exported and analyzed in Scival (Elsevier). Bibliographic data were described through absolute values and percentages in descriptive tables. VOSviewer was used to visualize collaborative networks.
    RESULTS: A total of 1920 documents were collected, and the highest percentage of these belonged to the area of neurology. Friedemann Paul was the author with the highest scientific production, but Brian Weinshenker had the greatest impact worldwide. Three of the institutions with the highest production were North American. Multiple sclerosis and related disorders were the journal with the highest production of publications. Most papers were published in Q1 or Q2 journals.
    CONCLUSION: NMOSD-related articles are mostly published in first and second quartile journals, which would reflect a high interest of the scientific community. Publications with international collaboration reported a higher impact. Although African and South American regions have considerable prevalence of this disease, they do not have institutions with high productivity developing research on this disease.
    Keywords:  Bibliometrics; neuromyelitis optica spectrum disorder; scientific production
    DOI:  https://doi.org/10.4103/ojo.ojo_300_22
  25. Prosthet Orthot Int. 2023 Aug 23.
    Global trends and current status of amputation: Bibliometrics and visual analysis of publications from 1999 to 2021.
    Ze Liu, Min Wang, Qi Liu, Biling Huang, Yuanyuan Teng, Mingliu Li, Shuqin Peng, Hongbin Guo, Jieyu Liang, Yi Zhang.
       OBJECTIVE: To generalize the research status, hotspots, and development trends of amputation-related research.
    METHODS: The data from 1999 to 2021 were collected from the Web of Science core collection database, and analyzed through bibliometrics software (CiteSpace and VOSviewer) for the dual-map overlay of journals, top 25 references with the strongest citation bursts, top 25 keywords with the strongest citation bursts, and timeline of keywords.
    RESULTS: A total of 8,588 literature studies were involved in this study. The United States ranks the first in terms of H-index, total number of publications, and total citations. US Department of Veterans Affairs, Veterans Health Administration, and University of Washington are the major contributors to amputation. Prosthetics and Orthotics International, Archives of Physical Medicine and Rehabilitation, and Journal of Rehabilitation Research and Development are the main publication channels for articles related to amputation. Geertzen JHB, Czerniecki J, and Dijkstra PU are major contributors to amputation. In addition, research on limb salvage treatment and surgical methods for amputation will become a hotspot in the future.
    CONCLUSION: The total number of publications for amputation has generally increased from 1999 to 2021. Our study is beneficial for scientists to specify the research hotspot and development direction of amputation.
    DOI:  https://doi.org/10.1097/PXR.0000000000000271
  26. Foods. 2023 Aug 15. pii: 3058. [Epub ahead of print]12(16):
    Trends in the Use of Lipases: A Systematic Review and Bibliometric Analysis.
    Lucely Nogueira Dos Santos, Rafael Firmani Perna, Ana Carolina Vieira, Alex Fernando de Almeida, Nelson Rosa Ferreira.
      Scientific mapping using bibliometric data network analysis was applied to analyze research works related to lipases and their industrial applications, evaluating the current state of research, challenges, and opportunities in the use of these biocatalysts, based on the evaluation of a large number of publications on the topic, allowing a comprehensive systematic data analysis, which had not yet been conducted in relation to studies specifically covering lipases and their industrial applications. Thus, studies involving lipase enzymes published from 2018 to 2022 were accessed from the Web of Science database. The extracted records result in the analysis of terms of bibliographic compatibility among the articles, co-occurrence of keywords, and co-citation of journals using the VOSviewer algorithm in the construction of bibliometric maps. This systematic review analysis of 357 documents, including original and review articles, revealed studies inspired by lipase enzymes in the research period, showing that the development of research, together with different areas of knowledge, presents good results related to the applications of lipases, due to information synchronization. Furthermore, this review showed the main challenges in lipase applications regarding increased production and operational stability; establishing well-defined evaluation criteria, such as cultivation conditions, activity, biocatalyst stability, type of support and reactor; thermodynamic studies; reuse cycles; and it can assist in defining goals for the development of successful large-scale applications, showing several points for improvement of future studies on lipase enzymes.
    Keywords:  VOSviewer; bibliometric study; immobilization; industrial applications; lipase; scaling up
    DOI:  https://doi.org/10.3390/foods12163058
  27. Medicine (Baltimore). 2023 Aug 18. 102(33): e34783
    Out-of-hospital cardiac arrest: A data-driven visualization of collaboration, frontier identification, and future trends.
    Yue Li, Zhaoying Li, Chunjie Li, Wei Cai, Tao Liu, Ji Li, Haojun Fan, Chunxia Cao.
      One of the main causes of death is out-of-hospital cardiac arrest (OHCA), which has a poor prognosis and poor neurological outcomes. This phenomenon has attracted increasing attention. However, there is still no published bibliometric analysis of OHCA. This bibliometric analysis of publications on OHCA aimed to visualize the current status of research, determine the frontiers of research, and identify future trends. Publications on OHCA were downloaded from the web of science database. The data elements included year, countries/territories, institutions, authors, journals, research areas, citations of publications, etc. Joinpoint regression and exponential models were used to identify and predict the trend of publications, respectively. Knowledge domain maps were applied to conduct contribution and collaboration, cooccurrence, cocitation, and coupled analyses. Timeline and burst detection analysis were used to identify the frontiers in the field. A total of 3 219 publications on OHCA were found from 1998 to 2022 (average annual percentage change = 16.7; 95% CI 14.4, 19.1). It was estimated that 859 articles and reviews would be published in 2025. The following research hotpots were identified: statement, epidemiology, clinical care, factors influencing prognosis and emergency medical services. The research frontier identification revealed that 7 categories were classified, including therapeutic hypothermia, emergency medical services, airway management, myocardial infarction, extracorporeal cardiopulmonary resuscitation, stroke foundation and trial. The burst detection analysis revealed that percutaneous coronary intervention, neurologic outcome, COVID-19 and extracorporeal cardiopulmonary resuscitation are issues that should be given continual attention in the future. This bibliometric analysis may reflect the current status and future frontiers of OHCA research.
    DOI:  https://doi.org/10.1097/MD.0000000000034783
  28. Heliyon. 2023 Aug;9(8): e18843
    Global trends in research of mitophagy in liver diseases over past two decades: A bibliometric analysis.
    Jie Lin, Yushun Chang, Meiling Hu, Qiuxia Gu, Jinyao Dai, Junjie Nan, Ziyuan Wang, Jiachen Chen, Danyang Zhong, Enjie Zhou, YiFan Wang, XiuJun Cai.
      Increasing evidence indicated that mitophagy might play a crucial role in the occurrence and progression of liver diseases. In order to enhance our understanding of the intricate relationship between mitophagy and liver diseases, a comprehensive bibliometric analysis of the existing literature in this field was conducted. This analysis aimed to identify key trends, potential areas of future research, and forecast the development of this specific field. We systematically searched the Web of Science Core Collection (WoSCC) for publications related to mitophagy in liver diseases from 2000 to 2022. We conducted the bibliometric analysis and data visualization through VOSviewer and CiteSpace. The analysis of publication growth revealed a substantial increase in articles published in this field over the past years, indicating mitophagy's growing interest and significance in liver diseases. China and USA emerged as the leading contributors in the number of papers, with 294 and 194 independent papers, respectively. Exploring the mechanism of mitophagy in the initiation and procession of liver diseases was the main content of studies in this field, and Parkin-independent mediated mitophagy has attracted much attention recently. "Lipid metabolism," "cell death," "liver fibrosis" and "oxidative stress" were the primary keywords clusters. Additionally, "nlrp3 inflammasome", "toxicity" and "nonalcoholic steatohepatitis" were emerging research hotspots in this area and have the potential to continue to be focal areas of investigation in the future. This study represents the first systematic bibliometric analysis of research on mitophagy in liver diseases conducted over the past 20 years. By providing an overview of the existing literature and identifying current research trends, this analysis sheds light on the critical areas of investigation and paves the way for future studies in this field.
    Keywords:  Bibliometric; CiteSpace; Liver diseases; Mitophagy; NLRP3 inflammasome; VOSviewer
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e18843
  29. Asian J Surg. 2023 Aug 23. pii: S1015-9584(23)01179-X. [Epub ahead of print]
    A bibliometric analysis of the factors influencing cervical spine surgery outcomes based on citespace.
    Hao Yuan, Fei Lei, Jiyuan Yan, Daxiong Feng.
      
    Keywords:  Bibliometric analysis; Cervical spondylosis; Influence factors; Surgery
    DOI:  https://doi.org/10.1016/j.asjsur.2023.08.035
  30. Front Bioeng Biotechnol. 2023 ;11 1210637
    Application of piezoelectric materials in the field of bone: a bibliometric analysis.
    Yu-Qin Zhang, Qian Geng, Chao Li, Hai-Cheng Wang, Chuan Ren, Yi-Fan Zhang, Jun-Sheng Bai, Hao-Bo Pan, Xu Cui, Meng-Xuan Yao, Wei Chen.
      In the past 4 decades, many articles have reported on the effects of the piezoelectric effect on bone formation and the research progress of piezoelectric biomaterials in orthopedics. The purpose of this study is to comprehensively evaluate all existing research and latest developments in the field of bone piezoelectricity, and to explore potential research directions in this area. To assess the overall trend in this field over the past 40 years, this study comprehensively collected literature reviews in this field using a literature retrieval program, applied bibliometric methods and visual analysis using CiteSpace and R language, and identified and investigated publications based on publication year (1984-2022), type of literature, language, country, institution, author, journal, keywords, and citation counts. The results show that the most productive countries in this field are China, the United States, and Italy. The journal with the most publications in the field of bone piezoelectricity is the International Journal of Oral & Maxillofacial Implants, followed by Implant Dentistry. The most productive authors are Lanceros-Méndez S, followed by Sohn D.S. Further research on the results obtained leads to the conclusion that the research direction of this field mainly includes piezoelectric surgery, piezoelectric bone tissue engineering scaffold, manufacturing artificial cochleae for hearing loss patients, among which the piezoelectric bone tissue engineering scaffold is the main research direction in this field. The piezoelectric materials involved in this direction mainly include polyhydroxybutyrate valerate, PVDF, and BaTiO3.
    Keywords:  BaTiO3; PHBV; PVDF; bibliometric; bone; piezoelectric; tissue engineering
    DOI:  https://doi.org/10.3389/fbioe.2023.1210637
  31. Int J Ophthalmol. 2023 ;16(8): 1356
    Comment on: Bibliometric analysis of glaucoma-related literature based on SCIE database: a 10-year literature analysis from 2009 to 2018.
    Yuh-Shan Ho.
      
    DOI:  https://doi.org/10.18240/ijo.2023.08.23
  32. JMIR Mhealth Uhealth. 2023 Aug 24. 11 e47553
    Current Status and Trends in mHealth-Based Research for Treatment and Intervention in Tinnitus: Bibliometric and Comparative Product Analysis.
    Yuanjia Hu, Yang Lu, Chenghua Tian, Yunfan He, Kaiyi Rong, Sijia Pan, Jianbo Lei.
       BACKGROUND: As a global medical problem, tinnitus can seriously harm human health and is difficult to alleviate, ranking among the top 3 complex diseases in the otolaryngology field. Traditional cognitive behavioral therapy and sound therapy require offline face-to-face treatment with medical staff and have limited effectiveness. Mobile health (mHealth), which, in recent decades, has been greatly applied in the field of rehabilitation health care, improving access to health care resources and the quality of services, has potential research value in the adjunctive treatment of tinnitus.
    OBJECTIVE: This study aimed to understand the research trends, product characteristics, problems, and research transformation of tinnitus treatment software by analyzing the research progress of mHealth for tinnitus treatment based on the literature and related marketed apps.
    METHODS: Bibliometric methods were used to describe the characteristics of the relevant literature in terms of the number and topics of publications, authors, and institutions. We further compared the features and limitations of the currently available tinnitus treatment software.
    RESULTS: Data published until February 28, 2022, were collected. Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) standardized screening process, 75 papers were included. The country with the highest number of publications was Germany, followed by the United Kingdom and the United States, whereas China had only a single relevant study. The most frequently found journals were the American Journal of Audiology and the Journal of the American Academy of Audiology (18/75, 24%). With regard to publication topics, cognitive behavioral therapy started to become a hot topic in 2017, and research on mHealth apps has increased. In this study, 28 tinnitus treatment apps were obtained (n=24, 86% from product data and n=4, 14% from literature data); these apps were developed mainly in the United States (10/28, 36%) or China (9/28, 32%). The main treatment methods were sound therapy (10/28, 36%) and cognitive behavioral therapy (2/28, 7%). Of the 75 publications, 7 (9%) described apps in the market stage. Of the 28 apps, 22 (79%) lacked literature studies or evidence from professional bodies.
    CONCLUSIONS: We found that, as a whole, the use of mHealth for treatment and intervention in tinnitus was showing a rapid development, in which good progress had been made in studies around sound therapy and cognitive behavioral therapy, although most of the studies (50/75, 67%) focused on treatment effects. However, the field is poorly accepted in top medical journals, and the majority are in the research design phase, with a lack of translation of the literature results and clinical validation of the marketed apps. Furthermore, in the future, novel artificial intelligence techniques should be used to address the issue of staged monitoring of tinnitus.
    Keywords:  application; bibliometrics; internet; mHealth; mobile health; mobile phone; software; tinnitus
    DOI:  https://doi.org/10.2196/47553
  33. Environ Res. 2023 Aug 21. pii: S0013-9351(23)01643-2. [Epub ahead of print] 116839
    The intersection of COVID-19 and air pollution: A systematic literature network analysis and roadmap for future research.
    Wong Ming Wong, Xing Wang, Yifan Wang.
      This paper employs systematic literature network analysis, including a literature review and bibliometric network analysis, to explore the COVID-19 and air pollution literature. A total of 1208 relevant documents from the Scopus database were analyzed using VOSviewer and SciMAT to examine author, keyword, and country interconnections. The paper addresses three research questions: (1) the latest studies on COVID-19 and air pollution, (2) influential authors, documents, and sources in the field, and (3) the study's findings as a roadmap for future research. Visual representations of author and country networks highlight influential entities based on citation rate. Keyword cluster analysis via VOSviewer summarizes connections based on link strength. The strategic diagram generated by SciMAT offers insights into future research directions in specific thematic keywords: (1) air pollution, (2) nitrogen dioxide, (3) epidemiology, and (4) atmospheric aerosol. This analysis enhances understanding of COVID-19 and air pollution and guides future research endeavors.
    Keywords:  Air pollution; COVID-19; SciMAT; Systematic literature network analysis; VOSviewer
    DOI:  https://doi.org/10.1016/j.envres.2023.116839
  34. Nutrients. 2023 Aug 11. pii: 3548. [Epub ahead of print]15(16):
    Food Composition Databases (FCDBs): A Bibliometric Analysis.
    Andy Wai Kan Yeung.
      Food composition databases (FCDBs) are important tools that provide information on the nutritional content of foods. Previously, it was largely unclear what nutritional contents and which FCDBs were involved in highly cited papers. The bibliometric study aimed to identify the most productive authors, institutions, and journals. The chemicals/chemical compounds with high averaged citations and FCDBs used by highly cited papers were identified. In July 2023, the online database Web of Science Core Collection (WoSCC) was queried to identify papers related to FCDBs. A total of 803 papers were identified and analyzed. The first paper indexed in WoSCC was published in 1992 by Pennington, which described the usefulness of FCDB for researchers to identify core foods for their own studies. In that paper, the FCDB described was the USDA 1987-88 NFCS (the United States Department of Agriculture 1987-88 Nationwide Food Consumption Survey). The most productive author was Dr. Paul M. Finglas, the Head of the Food Databanks National Capability at the Quadram Institute (Norwich, UK) and the Managing Director of EuroFIR. His most cited paper among this dataset was about the development of an online Irish food composition database together with EuroFIR. The most productive institutions were the USDA and the World Health Organization (WHO) instead of universities. Flavonoid was the most recurring chemical class among the highly cited ones. The anti-oxidative properties and protective effects against heart disease and cancer of flavonoids might be some of the reasons for their popularity in research. Among the highly cited papers, the most heavily used FCDBs were the USDA database for the flavonoid content of selected foods, Fineli, the USDA National Nutrient Database for Standard Reference (USNDB), EuroFIR eBASIS-Bioactive Substances in Food Information Systems, and Phenol-Explorer. High-quality national and international FCDBs should be promoted and made more accessible to the research and public communities to promote better nutrition and public health on a global scale.
    Keywords:  FCDB; VOSviewer; bibliometric; flavonoid; food composition database
    DOI:  https://doi.org/10.3390/nu15163548
  35. Acta Radiol. 2023 Aug 21. 2841851231189035
    Medical applications of generative adversarial network: a visualization analysis.
    Fan Zhang, Luyao Wang, Jiayin Zhao, Xinhong Zhang.
       BACKGROUND: Deep learning (DL) is one of the latest approaches to artificial intelligence. As an unsupervised DL method, a generative adversarial network (GAN) can be used to synthesize new data.
    PURPOSE: To explore GAN applications in medicine and point out the significance of its existence for clinical medical research, as well as to provide a visual bibliometric analysis of GAN applications in the medical field in combination with the scientometric software Citespace and statistical analysis methods.
    MATERIAL AND METHODS: PubMed, MEDLINE, Web of Science, and Google Scholar were searched to identify studies of GAN in medical applications between 2017 and 2022. This study was performed and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Citespace was used to analyze the number of publications, authors, institutions, and keywords of articles related to GAN in medical applications.
    RESULTS: The applications of GAN in medicine are not limited to medical image processing, but will also penetrate wider and more complex fields, or may be applied to clinical medicine. Eligibility criteria were the full texts of peer-reviewed journals reporting the application of GANs in medicine. Research selections included material published in English between 1 January 2017 and 1 December 2022.
    CONCLUSION: GAN has been fully applied to the medical field and will be more deeply and widely used in clinical medicine, especially in the field of privacy protection and medical diagnosis. However, clinical applications of GAN require consideration of ethical and legal issues. GAN-based applications should be well validated by expert radiologists.
    Keywords:  Citespace; Generative adversarial network; artificial intelligence; visualization analysis
    DOI:  https://doi.org/10.1177/02841851231189035
  36. Bioengineering (Basel). 2023 Aug 20. pii: 983. [Epub ahead of print]10(8):
    Exploring New Therapeutic Avenues for Ophthalmic Disorders: Glaucoma-Related Molecular Docking Evaluation and Bibliometric Analysis for Improved Management of Ocular Diseases.
    Flaviu Bodea, Simona Gabriela Bungau, Andrei Paul Negru, Ada Radu, Alexandra Georgiana Tarce, Delia Mirela Tit, Alexa Florina Bungau, Cristian Bustea, Tapan Behl, Andrei-Flavius Radu.
      Ophthalmic disorders consist of a broad spectrum of ailments that impact the structures and functions of the eye. Due to the crucial function of the retina in the vision process, the management of eye ailments is of the utmost importance, but several unmet needs have been identified in terms of the outcome measures in clinical trials, more proven minimally invasive glaucoma surgery, and a lack of comprehensive bibliometric assessments, among others. The current evaluation seeks to fulfill several of these unmet needs via a dual approach consisting of a molecular docking analysis based on the potential of ripasudil and fasudil to inhibit Rho-associated protein kinases (ROCKs), virtual screening of ligands, and pharmacokinetic predictions, emphasizing the identification of new compounds potentially active in the management of glaucoma, and a comprehensive bibliometric analysis of the most recent publications indexed in the Web of Science evaluating the management of several of the most common eye conditions. This method resulted in the finding of ligands (i.e., ZINC000000022706 with the most elevated binding potential for ROCK1 and ZINC000034800307 in the case of ROCK2) that are not presently utilized in any therapeutic regimen but may represent a future option to be successfully applied in the therapeutic scheme of glaucoma following further comprehensive testing validations. In addition, this research also analyzed multiple papers listed in the Web of Science collection of databases via the VOSviewer application to deliver, through descriptive analysis of the results, an in-depth overview of publications contributing to the present level of comprehension in therapeutic approaches to ocular diseases in terms of scientific impact, citation analyses, most productive authors, journals, and countries, as well as collaborative networks. Based on the molecular docking study's preliminary findings, the most promising candidates must be thoroughly studied to determine their efficacy and risk profiles. Bibliometric analysis may also help researchers set targets to improve ocular disease outcomes.
    Keywords:  bibliometric analysis; glaucoma; micropulse laser therapy; molecular docking; ocular disease therapy; retinal diseases
    DOI:  https://doi.org/10.3390/bioengineering10080983
  37. Cell Signal. 2023 Aug 18. pii: S0898-6568(23)00269-3. [Epub ahead of print] 110855
    Navigating the landscape of Rho GTPase signalling system in autoimmunity: A bibliometric analysis spanning over three decades (1990 to 2023).
    Chien Fung Chong, Nik Yasmin Umaira Hasnizan, Ana Masara Ahmad Mokhtar.
      Ras-homologous (Rho) guanosine triphosphatases (GTPases) are considered a central player in regulating various biological processes, extending to immune regulation. Perturbations in Rho GTPase signalling have been implicated in immune-related dysregulation, contributing to the development of autoimmunity. This study presents a scientometric analysis exploring the interlink between the Rho GTPase signalling system and autoimmunity, while also delving into the trends of past studies. A total of 967 relevant publications from 1990 to 2023 were retrieved from the Web of Science Core Collection database after throrough manual filtering of irrelevant articles. The findings show an upward trajectory in publications related to this field since 2006. Over the past three decades, the United States of America (41.68%) emerged as the primary contributor in advancing our understanding of the association between the Rho GTPase signalling system and autoimmunity. Research in autoimmunity has mainly centered around therapeutic interventions, with an emphasis on studying leukocyte (macrophage) and endothelial remodelling. Interestingly, within the domains of multiple sclerosis and rheumatoid arthritis, the current focus has been directed towards comprehending the role of RhoA, Rac1, and Cdc42. Notably, certain subfamilies of Rho (such as RhoB and RhoC), Rac (including Rac2 and RhoG), Cdc42 (specifically RhoJ), and other atypical Rho GTPases (like RhoE and RhoH) consistently demonstrating compelling link with autoimmunity, but still warrants emphasis in the future study. Hence, strategic manipulation of the Rho signalling system holds immense promise as a pivotal approach to addressing the global challenge of autoimmunity.
    Keywords:  Autoimmune; Bibliometrics; Inflammation; Rho GTPases; VOSviewer
    DOI:  https://doi.org/10.1016/j.cellsig.2023.110855
  38. JMIR Serious Games. 2023 Aug 21. 11 e44766
    Virtual Reality Technology in Nursing Professional Skills Training: Bibliometric Analysis.
    Chengang Hong, Liping Wang.
       BACKGROUND: Nursing professional skills training has undergone significant transformation due to the exponential growth of computer and medical technology. The innovative use of virtual reality (VR) in nursing education has emerged as a cutting-edge technical support technique that has gained attention as a highly effective method for improving nurse training quality.
    OBJECTIVE: This study aims to review the current status of VR technology in nursing professional skills training, research hotspots, and emerging trends in the last 15 years.
    METHODS: The Web of Science Core Collection database was used to search for literature on VR technology in nursing professional skills training covering the period from 2006 to 2022. Biblioshiny (K-Synth Srl) was used to import and convert the records to Bibliometrix (K-Synth Srl) for analysis, and R (R Core Team) was used for descriptive bibliometric analysis. VOSviewer (Leiden University) was used to cluster co-occurring keywords, and Scimago Graphica (version 1.0.16; Scimago Lab) was used to generate a geographical visualization of published countries and regions.
    RESULTS: A total of 1073 papers were analyzed, indicating a surge in research on the application of VR in nursing professional skills training in recent years, as evidenced by a positive trend in annual publication of relevant literature. The majority of studies were from the United States (n=340) and Canada (n=107), and Margaret Verkuyl was the most prolific author, leading the way with 9 publications. Furthermore, "Computerized Virtual Patients in Health Professions Education: a Systematic Review and Meta-Analysis" was the most frequently cited reference. Keywords such as education, simulation, skills, students, and care were most commonly used by researchers.
    CONCLUSIONS: The bibliometric analysis provides a comprehensive overview of the use of VR in nursing professional skills training, indicating that VR-based training is an effective means of improving the skills and competencies of nursing students and professionals alike. The COVID-19 pandemic has reinforced the importance of developing VR-based distance education, despite challenges such as integrating virtual and real-world training and mitigating safety risks.
    Keywords:  AR; VR; XR; augmented reality; bibliometric analysis; extended reality; mixed reality; nursing professional skills; virtual reality; visual content analysis
    DOI:  https://doi.org/10.2196/44766
  39. Sensors (Basel). 2023 Aug 21. pii: 7290. [Epub ahead of print]23(16):
    The Role of Ultrasound in Cancer and Cancer-Related Pain-A Bibliometric Analysis and Future Perspectives.
    Badrinathan Sridharan, Alok Kumar Sharma, Hae Gyun Lim.
      Ultrasound has a deep penetrating ability with minimal or no tissue injury, while cancer-mediated complications during diagnosis, therapy, and surgery have become a serious challenge for clinicians and lead to the severity of the primary condition (cancer). The current study highlights the importance of ultrasound imaging and focused ultrasound therapy during cancer diagnosis, pain reduction, guidance for surgical resection of cancer, and the effectiveness of chemotherapy. We performed the bibliometric analysis on research domains involving ultrasound, cancer management, pain, and other challenges (chemotherapy, surgical guidance, and postoperative care), to observe the trend by which the research field has grown over the years and propose a possible future trend. The data was obtained from the Web of Science, processed, and exported as plain text files for analysis in the Bibliometrix R web interface using the Biblioshiny package. A total of 3248 documents were identified from 1100 journal sources. A total of 390 articles were published in 2022, with almost a 100% growth rate from previous years. Based on the various network analysis, we conclude that the outcome of the constant research in this domain will result in better patient care during the management of various diseases, including cancer and other co-morbidities.
    Keywords:  acousitc waves; bibliometry; nociception; pain; tumor; ultrasound
    DOI:  https://doi.org/10.3390/s23167290
  40. Environ Manage. 2023 Aug 23.
    Omernik's Ecoregion Framework: a Legacy for Understanding Regional Patterns in Attainable Resource Quality.
    Renata Ruaro, Éder André Gubiani, Robert M Hughes.
      An initial and comprehensive map of ecological regions across the conterminous United States was provided by Omernik in 1987. Because that paper was the most-cited published by the Annals of the American Association of Geographers, we sought to assess and quantify its contribution to science. To do so, we conducted a scientometric analysis to address the following main questions: 1) What are the temporal and spatial citation trends? We expected that Omernik's paper would still be employed 36 years after its publication, and mostly in the United States of America. 2) For what types of environments and organisms has it been applied? Based on its generality, we expected that it had been applied to both terrestrial and aquatic ecosystems. 3) What are the main applications of Omernik's article? We predicted that it would mostly be used for describing and delineating study sites and management areas, as well as for selecting regional reference sites. The number of citations presented a positive temporal increase, indicating its continued applicability. Most papers dealt with aquatic environments, mainly in streams carried out predominantly in the United States of America, as was one of its earliest applications. The usefulness of ecoregions for assessing and managing biotic and abiotic patterns and distributions were the main topics addressed by scientists. Ecoregions have offered a general framework for developing regional expectations and rational regional management policies across large areas, as was their original intent. In addition, ecoregion maps were used for communicating patterns-or the lack of them-to interested scientists, citizens, and decision-makers. That comprehensiveness of Omernik's ecoregion approach has led to its widespread applicability and continued usefulness to a diverse set of scientific and management disciplines.
    Keywords:  Conterminous United States; Ecosystem classification; Geographic patterns; Regionalization; Water quality.
    DOI:  https://doi.org/10.1007/s00267-023-01871-4
  41. Br Dent J. 2023 Aug;235(4): 234
    Correction to: Citation context.
    A Kaushik.
      
    DOI:  https://doi.org/10.1038/s41415-023-6226-6
  42. Front Res Metr Anal. 2023 ;8 1067981
    The positive impact on translational research of Fondazione italiana di ricerca per la Sclerosi Laterale Amiotrofica (AriSLA), a non-profit foundation focused on amyotrophic lateral sclerosis. Convergence of ex-ante evaluation and ex-post outcomes when goals are set upfront.
    Stefania Guareschi, Maddalena Ravasi, Danila Baldessari, Silvia Pozzi, Tiziana Zaffino, Mario Melazzini, Anna Ambrosini.
      Charities investing on rare disease research greatly contribute to generate ground-breaking knowledge with the clear goal of finding a cure for their condition of interest. Although the amount of their investments may be relatively small compared to major funders, the advocacy groups' clear mission promotes innovative research and aggregates highly motivated and mission-oriented scientists. Here, we illustrate the case of Fondazione italiana di ricerca per la Sclerosi Laterale Amiotrofica (AriSLA), the main Italian funding agency entirely dedicated to amyotrophic lateral sclerosis research. An international benchmark analysis of publications derived from AriSLA-funded projects indicated that their mean relative citation ratio values (iCite dashboard, National Institutes of Health, U.S.) were very high, suggesting a strong influence on the referring international scientific community. An interesting trend of research toward translation based on the "triangle of biomedicine" and paper citations (iCite) was also observed. Qualitative analysis on researchers' accomplishments was convergent with the bibliometric data, indicating a high level of performance of several working groups, lines of research that speak of progression toward clinical translation, and one study that has progressed from the investigation of cellular mechanisms to a Phase 2 international clinical trial. The key elements of the success of the AriSLA investment lie in: (i) the clear definition of the objectives (research with potential impact on patients, no matter how far), (ii) a rigorous peer-review process entrusted to an international panel of experts, (iii) diversification of the portfolio with ad hoc selection criteria, which also contributed to bringing new experts and younger scientists to the field, and (iv) a close interaction of AriSLA stakeholders with scientists, who developed a strong sense of belonging. Periodic review of the portfolio of investments is a vital practice for funding agencies. Sharing information between funding agencies about their own policies and research assessment methods and outcomes help guide the international debate on funding strategies and research directions to be undertaken, particularly in the field of rare diseases, where synergy is a relevant enabling factor.
    Keywords:  ALS research; RCR; amyotrophic lateral sclerosis; relative citation ratio; research assessment
    DOI:  https://doi.org/10.3389/frma.2023.1067981
  43. Crit Rev Food Sci Nutr. 2023 Aug 21. 1-17
    Probiotics and biofilm interaction in aquaculture for sustainable food security: A review and bibliometric analysis.
    Md Ashikur Rahman, Md Ashrafudoulla, Shirin Akter, Si Hong Park, Sang-Do Ha.
      Aquaculture is one of the most significant food sources from the prehistoric period. As aquaculture intensifies globally, the prevalence and outbreaks of various pathogenic microorganisms cause fish disease and heavy mortality, leading to a drastic reduction in yield and substantial economic loss. With the modernization of the aquaculture system, a new challenge regarding biofilms or bacterial microenvironments arises worldwide, which facilitates pathogenic microorganisms to survive under unfavorable environmental conditions and withstand various treatments, especially antibiotics and other chemical disinfectants. However, we focus on the mechanistic association between those microbes which mainly form biofilm and probiotics in one of the major food production systems, aquaculture. In recent years, probiotics and their derivatives have attracted much attention in the fisheries sector to combat the survival strategy of pathogenic bacteria. Apart from this, Bibliometric analysis provides a comprehensive overview of the published literature, highlighting key research themes, emerging topics, and areas that require further investigation. This information is valuable for researchers, policymakers, and stakeholders in determining research priorities and allocating resources effectively.
    Keywords:  Probiotics; aquaculture; biofilm; promising strategies
    DOI:  https://doi.org/10.1080/10408398.2023.2249114
  44. PLoS One. 2023 ;18(8): e0289931
    Machine learning models can predict subsequent publication of North American Spine Society (NASS) annual general meeting abstracts.
    Aazad Abbas, Olumide Olotu, Akeshdeep Bhatia, Denis Selimovic, Alireza Tajik, Jeremie Larouche, Henry Ahn, Albert Yee, Stephen Lewis, Joel Finkelstein, Jay Toor.
       BACKGROUND CONTEXT: Academic meetings serve as an opportunity to present and discuss novel ideas. Previous studies have identified factors predictive of publication without generating predictive models. Machine learning (ML) presents a novel tool capable of generating these models. As such, the objective of this study was to use ML models to predict subsequent publication of abstracts presented at a major surgical conference.
    STUDY DESIGN/SETTING: Database study.
    METHODS: All abstracts from the North American Spine Society (NASS) annual general meetings (AGM) from 2013-2015 were reviewed. The following information was extracted: number of authors, institution, location, conference category, subject category, study type, data collection methodology, human subject research, and FDA approval. Abstracts were then searched on the PubMed, Google Scholar, and Scopus databases for publication. ML models were trained to predict whether the abstract would be published or not. Quality of models was determined by using the area under the receiver operator curve (AUC). The top ten most important factors were extracted from the most successful model during testing.
    RESULTS: A total of 1119 abstracts were presented, with 553 (49%) abstracts published. During training, the model with the highest AUC and accuracy metrics was the partial least squares (AUC of 0.77±0.05, accuracy of 75.5%±4.7%). During testing, the model with the highest AUC and accuracy was the random forest (AUC of 0.69, accuracy of 67%). The top ten features for the random forest model were (descending order): number of authors, year, conference category, subject category, human subjects research, continent, and data collection methodology.
    CONCLUSIONS: This was the first study attempting to use ML to predict the publication of complete articles after abstract presentation at a major academic conference. Future studies should incorporate deep learning frameworks, cognitive/results-based variables and aim to apply this methodology to larger conferences across other fields of medicine to improve the quality of works presented.
    DOI:  https://doi.org/10.1371/journal.pone.0289931
  45. J Orthop Surg Res. 2023 Aug 21. 18(1): 610
    Incidence of periprosthetic joint infection after primary total hip arthroplasty is underestimated: a synthesis of meta-analysis and bibliometric analysis.
    Zi-Jun Zeng, Fang-Ming Yao, Wei He, Qiu-Shi Wei, Min-Cong He.
      The American Musculoskeletal Society updated the diagnostic criteria for periprosthetic joint infection (PJI) in 2011 and 2018. However, the overall incidence of PJI since the introduction of these new standards has not been assessed. In order to fill this knowledge gap, a single-group meta-analysis was conducted using articles obtained from several databases, focusing on the incidence of PJI after primary total hip arthroplasty (THA). Our study revealed a significant difference in the incidence of PJI reported by different national or regional databases. Moreover, most cases of PJI were found to be underestimated. This highlights the crucial need for standardized diagnostic criteria and monitoring methods to accurately identify and track cases of PJI. Furthermore, a bibliometric analysis was conducted to provide a comprehensive overview of the current state of research on PJI after THA. This analysis explored the most productive countries, organizations, journals, and individuals in this research area. Additionally, it identified the research trends and hotspots of the last decade, highlighting the advancements and areas of focus in this field. By conducting these analyses, the study aims to contribute to the understanding of PJI after THA and provide valuable insights for clinicians, researchers, and policymakers involved in the management of this condition.
    Keywords:  Arthroplasty; Bibliometrics; Epidemiology; Incidence; Meta-analysis; PJI; Periprosthetic joint infection; THA
    DOI:  https://doi.org/10.1186/s13018-023-04060-5
  46. Aesthet Surg J. 2023 Aug 23. pii: sjad277. [Epub ahead of print]
    Medical Applications of Artificial Intelligence and Large Language Models: Bibliometric Analysis and Stern Call for Improved Publishing Practices.
    Jad Abi-Rafeh, Hong Hao Xu, Roy Kazan, Heather J Furnas.
      
    DOI:  https://doi.org/10.1093/asj/sjad277
  47. Cancer Control. 2023 Jan-Dec;30:30 10732748231195439
    Artificial Intelligence and Machine Learning in Cancer Research: A Systematic and Thematic Analysis of the Top 100 Cited Articles Indexed in Scopus Database.
    Ibrahim H Musa, Lukman O Afolabi, Ibrahim Zamit, Taha H Musa, Hassan H Musa, Andrew Tassang, Tosin Y Akintunde, Wei Li.
      
    Keywords:  Artificial Intelligence; Machine Learning; Cancer Research
    DOI:  https://doi.org/10.1177/10732748231195439
  48. Aesthetic Plast Surg. 2023 Aug 22.
    Adipose Tissue-Derived Stem Cells in Plastic and Reconstructive Surgery: A Bibliometric Study.
    Rosita Pensato, Rasmieh Al-Amer, Simone La Padula.
      
    DOI:  https://doi.org/10.1007/s00266-023-03586-7
  49. J Surg Res. 2023 Aug 19. pii: S0022-4804(23)00277-9. [Epub ahead of print]292 97-104
    Trauma and Critical Care Military-Civilian Publications Increased After the COVID-19 Pandemic: A Literature Review.
    Joseph Lee, Laura Roberson, Reid Garner, Eungjae Kim, Jacob Glaser, Pamela Choi, Diego Vicente.
       INTRODUCTION: There continues to be a growing demand for military-civilian partnerships (MCPs) in research collaborations developing medical trauma care in domestic and international affairs. The objective of this comprehensive review is to investigate the difference in the quantity of MCP trauma and critical care publications before and after the COVID-19 pandemic.
    METHODS: A systematic literature review was performed for the calendar years 2018 and 2021 utilizing MEDLINE, Cochrane, and EMBASE databases. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we performed a three-tiered review of 603 English language articles to identify trauma-related military and/or civilian partners and describe the changes in geographical relationships.
    RESULTS: A total of 96 (2018) and 119 (2021) articles met screening criteria for trauma and critical care studies and were used for final data extraction. Ultimately, 59 (2018) and 71 (2021) papers met the inclusion criteria of identifying trauma/critical care MCPs and identified both military and civilian partners. There was also an increase from 10 (2018) to 17 (2021) publications that mentioned advocacy for MCP. Using the author affiliations, four regional MCP types were recorded: of 2018 articles, locoregional (3.4%), US-national (47.5%), single international country (42.4%), and between multiple countries (6.8%); of 2021 articles, locoregional (15.5%), US-national (38%), single international country (29.6%), and between multiple countries (16.9%). There has been an increase in the number of locoregional and multinational MCPs and an overall increase in the number of collaborative trauma publications and MCP advocacy papers. A national geographical heat map was developed to illustrate the changes from 2018 to 2021.
    CONCLUSIONS: There has been an increase in the number of recorded trauma and critical care MCP publications post-pandemic. The growth in the number of manuscripts in more regions post-pandemic suggests an increase in the recognition of collaborations that contribute not only to conflict readiness but also advancements in trauma and surgical care.
    Keywords:  Critical care; Military civilian partnerships; Surgical research; Trauma
    DOI:  https://doi.org/10.1016/j.jss.2023.06.025
  50. Int J Food Sci Nutr. 2023 Aug 23. 1-13
    Fermented foods and beverages: a potential in situ vitamin B12 biofortification - a literature review.
    Marcelo Gomes Soares, Gabriel Cicalese Bevilaqua, Érika Maria Marcondes Tassi, Vivian Consuelo Reolon Schmidt.
      Millions of dollars have been increasingly spent on plant-based diets. Considering that vitamin B12 is obtained from the consumption of animal-derived foods, new sources of vitamin B12 and methods of food fortification are being eagerly sought. Therefore, this work aims to evaluate advances in situ fermentation processes of food and beverages produced on a large scale and industrial applications for obtaining cobalamin-rich products. Bibliometric analysis was performed and revealed that several studies report a great capacity for in situ biofortification of B12 in foods, mostly on the use of propionic (PB) and lactic (LAB) bacteria. In this context, market potentials for such products, the main microorganisms, including simultaneous cultures, and their respective applications have been presented herein. Although knowledge on potential applications is still limited, field research has been increasingly conducted, thus revealing scientific and technological opportunities, both for the production and the stability of B12 found in plant-based foods.
    Keywords:  Bibliometric analysis; biosynthesis; cobalamin; fermentation; plant-based
    DOI:  https://doi.org/10.1080/09637486.2023.2248422
  51. Foods. 2023 Aug 09. pii: 3007. [Epub ahead of print]12(16):
    Xylooligosaccharides: A Bibliometric Analysis and Current Advances of This Bioactive Food Chemical as a Potential Product in Biorefineries' Portfolios.
    Tainá Manicardi, Gabriel Baioni E Silva, Andreza A Longati, Thiago D Paiva, João P M Souza, Thiago F Pádua, Felipe F Furlan, Raquel L C Giordano, Roberto C Giordano, Thais S Milessi.
      Xylooligosaccharides (XOS) are nondigestible compounds of great interest for food and pharmaceutical industries due to their beneficial prebiotic, antibacterial, antioxidant, and antitumor properties. The market size of XOS is increasing significantly, which makes its production from lignocellulosic biomass an interesting approach to the valorization of the hemicellulose fraction of biomass, which is currently underused. This review comprehensively discusses XOS production from lignocellulosic biomass, aiming at its application in integrated biorefineries. A bibliometric analysis is carried out highlighting the main players in the field. XOS production yields after different biomass pretreatment methods are critically discussed using Microsoft PowerBI® (2.92.706.0) software, which involves screening important trends for decision-making. Enzymatic hydrolysis and the major XOS purification strategies are also explored. Finally, the integration of XOS production into biorefineries, with special attention to economic and environmental aspects, is assessed, providing important information for the implementation of biorefineries containing XOS in their portfolio.
    Keywords:  bibliometric analysis; biorefineries; economic aspects; environmental impact; lignocellulosic biomass; xylooligosaccharides
    DOI:  https://doi.org/10.3390/foods12163007
  52. J Cardiovasc Comput Tomogr. 2023 Aug 22. pii: S1934-5925(23)00412-4. [Epub ahead of print]
    Comparison of the rate of change (slopes) in impact factor of medical imaging journals unveils journals with organic growth: An observational study (2016-2022).
    Paola Martínez-Greiser, Melissa Garcia-Lezama, Santiago Rivera-Ibarguen, Ernesto Roldan-Valadez.
      
    DOI:  https://doi.org/10.1016/j.jcct.2023.08.005
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