bims-evares Biomed News
on Evaluation of research
Issue of 2023–07–02
110 papers selected by
Thomas Krichel, Open Library Society



  1. Eur J Med Res. 2023 Jun 24. 28(1): 194
       BACKGROUND: One of the most prominent features of living organisms is their circadian rhythm, which governs a wide range of physiological processes and plays a critical role in maintaining optimal health and function in response to daily environmental changes. This work applied bibliometric analysis to explore quantitative and qualitative trends in circadian rhythm in cardiovascular diseases (CVD). It also aims to identify research hotspots and provide fresh suggestions for future research.
    METHODS: The Web of Science Core Collection was used to search the data on circadian rhythm in CVD. HistCite, CiteSpace, and VOSviewer were used for bibliometric analysis and visualization. The analysis included the overall distribution of yearly outputs, top nations, active institutions and authors, core journals, co-cited references, and keywords. To assess the quality and efficacy of publications, the total global citation score (TGCS) and total local citation score (TLCS) were calculated.
    RESULTS: There were 2102 papers found to be associated with the circadian rhythm in CVD, with the overall number of publications increasing year after year. The United States had the most research citations and was the most prolific country. Hermida RC, Young ME, and Ayala DE were the top three writers. The three most notable journals on the subject were Chronobiology International, Hypertension Research, and Hypertension. In the early years, the major emphasis of circadian rhythm in CVD was hormones. Inflammation, atherosclerosis, and myocardial infarction were the top developing research hotspots.
    CONCLUSION: Circadian rhythm in CVD has recently received a lot of interest from the medical field. These topics, namely inflammation, atherosclerosis, and myocardial infarction, are critical areas of investigation for understanding the role of circadian rhythm in CVD. Although they may not be future research priorities, they remain of significant importance. In addition, how to implement these chronotherapy theories in clinical practice will depend on additional clinical trials to get sufficient trustworthy clinical evidence.
    Keywords:  Chronotherapy; Citespace; Diurnal rhythm; Heart; Research trends
    DOI:  https://doi.org/10.1186/s40001-023-01158-8
  2. Front Med (Lausanne). 2023 ;10 1194005
       Background: Acupuncture anesthesia is a significant technical development that originated in China in 1958 and was introduced to the West in the early 1970s. Due to its relative novelty, it has been the subject of intense scrutiny and contestation. Since the early 1970s, the use of acupuncture as a complementary treatment for opioid analgesics has been accepted. Research on acupuncture anesthesia has helped to reduce clinical opioid abuse. However, only a few articles have focused on previous publications that reflect the trend of the study, the main investigators, reciprocal collaboration, and other information in this field. In view of this, we utilized bibliographic analysis methods to objectively analyze current trends and research hotspots in this field, aiming to provide a foundation and reference for future studies.
    Methods: The Web of Science database was searched for publications related to acupuncture anesthesia between 1992 and 2022. The CiteSpace and VOSviewer were used to analyze the annual publications, authors, Co-cited authors, and their countries (regions) and institutions, co-occurrence keywords, burst keywords, Co-citation references and Co-citation journals.
    Results: A total of 746 eligible publications were retrieved from the database for the analysis, including 637 articles and 109 reviews. And the trend of annual publications continued to grow. Aashish J. Kumar, Daniel I. Sessler, Baoguo Wang, and Paul F. White published the most papers in this field (7), and all authors, had a very low centrality (<0.01). China (252) and the University of California System (21) were the most productive country (region) and institution, respectively, while the United States (0.62) and University of California System (0.16) had the highest centrality. After removing keywords related to the search strategy, the three most frequent were pain (115), electroacupuncture (109), and stimulation (91). The six most recent burst keywords were recovery, transcutaneous electrical acupoint stimulation, systematic review, quality, general anesthesia, and surgery. Wang et al.'s article had the highest co-citation count (20), whereas Zhang et al.'s articles had the highest centrality (0.25). The Journal of Anesthesia and Analgesia was the most influential one (408 co-citations).
    Conclusion: This research provides valuable information for the study of acupuncture anesthesia. In recent years, frontier topics in acupuncture anesthesia research have been the promotion of perioperative rehabilitation, anesthesia management, and quality improvement.
    Keywords:  CiteSpace; VOSviewer; acupuncture; anesthesia; bibliometric analysis
    DOI:  https://doi.org/10.3389/fmed.2023.1194005
  3. Front Med (Lausanne). 2023 ;10 1158519
       Purpose: Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a dangerous symptom in patients with severe viral pneumonia. This study aims to comprehensively review the cooperation and influence of countries, institutions, authors and co-cited journals/authors/references and keywords in the field of ALI/ARDS associated with viral pneumonia from the perspective of bibliometrics, evaluate the clustering evolution of knowledge structure, and find hot trends and emerging topics.
    Methods: Publications on ALI/ARDS associated with viral pneumonia published from January 1, 1992 to December 31, 2022 were extracted from the Web of Science core collection. The document type was limited to original article or review, with the language set to English. Citespace was used to conduct the bibliometric analysis.
    Results: A total of 929 articles were included, and the number of them generally increased over time. The countries with the most published articles in this field are the United States (320 papers) and Fudan University is the institution (15 papers) with the most research results. The New England Journal of Medicine was the most frequently co-cited journal, while the most influential co-cited journal was American Journal of Clinical Pathology. Reinout A Bem and Cao Bin were the most prolific author, but there was no leader in this field. The keywords with both high frequency and high centrality were "pneumonia" (Freq = 169, Central = 0.15), "infection" (Freq = 133, Central = 0.15), "acute lung injury" (Freq = 112, Central = 0.18), "respiratory distress syndrome" (Freq = 108, Central = 0.24), and "disease" (Freq = 61, Central = 0.17). "Failure" was the first keyword with citation bursts. Meanwhile, "coronavirus," "cytokine storm" and "respiratory syndrome coronavirus" continue to burst.
    Conclusion: Although there was a surge in literature since 2020, attentions to ALI/ARDS associated with viral pneumonia were still insufficient over last three decades. The communication and cooperation among countries, institutions and authors need to be further strengthened.
    Keywords:  acute lung injury; acute respiratory distress syndrome; bibliometrics; viral pneumonia; virus
    DOI:  https://doi.org/10.3389/fmed.2023.1158519
  4. Orthop J Sports Med. 2023 Jun;11(6): 23259671231168875
       Background: Textbook knowledge and clinical dogma are often insufficient for effective evidence-based decision making when treating musculoskeletal injuries in American football players, given the variability in presentation and outcomes across different sports and different levels of competition. Key evidence can be drawn directly from high-quality published articles to make the appropriate decisions and recommendations for each athlete's unique situation.
    Purpose: To identify and analyze the 50 most cited articles related to football-related musculoskeletal injury to provide an efficient tool in the arsenal of trainees, researchers, and evidence-based practitioners alike.
    Study Design: Cross-sectional study.
    Methods: The ISI Web of Science and SCOPUS databases were queried for articles pertaining to musculoskeletal injury in American football. For each of the top 50 most cited articles, bibliometric elements were evaluated: citation count and density, decade of publication, journal, country, multiple publications by the same first author or senior author, article content (topic, injury area), and level of evidence (LOE).
    Results: The mean ± SD number of citations was 102.76 ± 37.11; the most cited article, with 227 citations, was "Syndesmotic Ankle Sprains" published in 1991 by Boytim et al. Several authors served as a first or senior author on >1 publication, including J.S. Torg (n = 6), J.P. Bradley (n = 4), and J.W. Powell (n = 4). The American Journal of Sports Medicine published the majority of the 50 most cited articles (n = 31). A total of 29 articles discussed lower extremity injuries, while only 4 discussed upper extremity injuries. The majority of the articles (n = 28) had an LOE of 4, with only 1 article having an LOE of 1. The articles with an LOE of 3 had the highest mean citation number (133.67 ± 55.23; F = 4.02; P = .05).
    Conclusion: The results of this study highlight the need for more prospective research surrounding the management of football-related injury. The low overall number of articles on upper extremity injury (n = 4) also highlights an area for further research.
    Keywords:  American football; bibliometric analysis; citation; injury
    DOI:  https://doi.org/10.1177/23259671231168875
  5. J Pain Res. 2023 ;16 2115-2129
       Background: Research on the brain mechanisms underlying manual therapy (MT)-induced analgesia has been conducted worldwide. However, no bibliometric analysis has been performed on functional magnetic resonance imaging (fMRI) studies of MT analgesia. To provide a theoretical foundation for the practical application of MT analgesia, this study examined the current incarnation, hotspots, and frontiers of fMRI-based MT analgesia research over the previous 20 years.
    Methods: All publications were obtained from the Science Citation Index-Expanded (SCI-E) of Web of Science Core Collection (WOSCC). We used CiteSpace 6.1.R3 to analyze publications, authors, cited authors, countries, institutions, cited journals, references, and keywords. We also evaluated keyword co-occurrences and timelines, and citation bursts. The search was conducted from 2002-2022 and was completed within one day on October 7, 2022.
    Results: In total, 261 articles were retrieved. The total number of annual publications showed a fluctuating but overall increasing trend. Author B. Humphreys had the highest number of publications (eight articles) and J. E. Bialosky had the highest centrality (0.45). The United States of America (USA) was the country with the most publications (84 articles), accounting for 32.18% of all publications. Output institutions were mainly the University of Zurich, University of Switzerland, and the National University of Health Sciences of the USA. The Spine (118) and the Journal of Manipulative and Physiological Therapeutics (80) were most frequently cited. The four hot topics in fMRI studies on MT analgesia were "low back pain", "magnetic resonance imaging", "spinal manipulation", and "manual therapy." The frontier topics were "clinical impacts of pain disorders" and "cutting-edge technical capabilities offered by magnetic resonance imaging".
    Conclusion: fMRI studies of MT analgesia have potential applications. fMRI studies of MT analgesia have linked several brain areas, with the default mode network (DMN) garnering the most attention. Future research should include international collaboration and RCTs on this topic.
    Keywords:  CiteSpace; analgesia; bibliometric analysis; functional magnetic resonance imaging; manual therapy; web of science
    DOI:  https://doi.org/10.2147/JPR.S412658
  6. Front Oncol. 2023 ;13 1111296
       Introduction: The bibliometric analysis aims to identify research trends in estrogen receptor (ERs) and progesterone receptor (PRs) in prostate cancer (PCa), and also discuss the hotspots and directions of this field.
    Methods: 835 publications were sourced from the Web of Science database (WOS) from 2003 to 2022. Citespace, VOSviewer, and Bibliometrix were used for the bibliometric analysis.
    Results: The number of published publications increased in early years, but declined in the last 5 years. The United States was the leading country in citations, publications, and top institutions. Prostate and Karolinska Institutet were the most publications of journal and institution, respectively. Jan-Ake Gustafsson was the most influential author based on the number of citations/publications. The most cited paper was "Estrogen receptors and human disease" by Deroo BJ, published in the Journal of Clinical Investigation. The most frequently used keywords were PCa (n = 499), gene-expression (n = 291), androgen receptor (AR) (n = 263), and ER (n = 341), while ERb (n = 219) and ERa (n = 215) further emphasized the importance of ER.
    Conclusions: This study provides useful guidance that ERa antagonists, ERb agonists, and the combination of estrogen with androgen deprivation therapy (ADT) will potentially serve as a new treatment strategy for PCa. Another interesting topic is relationships between PCa and the function and mechanism of action of PRs subtypes. The outcome will assist scholars in gaining a comprehensive understanding of the current status and trends in the field, and provide inspiration for future research.
    Keywords:  Bibliometrix; Citespace; VOSviewer; bibliometric analysis; estrogen receptor; progesterone receptor; prostate cancer
    DOI:  https://doi.org/10.3389/fonc.2023.1111296
  7. Environ Dev Sustain. 2023 Mar 19. 1-27
      This study aims to highlight the current trends in the literature on sustainability by applying a bibliometric review of papers on sustainability published in Environment, Development and Sustainability. Bibliometric analysis is a quantitative approach to bibliographic materials that highlights the core theoretical and empirical research on a specific field. In addition, it allows the classification of previous studies. Previous bibliometric reviewers were limited to sustainability papers in specific industries, while this study considers all papers on sustainability to provide further insights on overall sustainability topics. The analysis was based on keyword cartography analysis, bibliometric authors' citation analysis, bibliometric papers' citation analysis, bibliometric references' co-citation analysis, journals' co-citation cartography, and qualitative content analysis. A total of 997 articles on sustainability were reviewed. Bibliometric analysis was performed using VOSviewer and content analysis was performed using WordStat. Six major clusters were identified: environmental sustainability, sustainable development, urban sustainability, ecological footprint, environment, and climate change. In addition, the results reveal that Environment, Development and Sustainability has increasingly experienced important growth in research papers and citations, reflecting its significant contribution to the sustainability research field. In addition, this study presents recommendations for future research opportunities in the field of sustainability. The findings of this study have implications for sustainability research, such as the assessment of environmental and social sustainability in multinational institutional contexts and across industries as well as the examination of the impact of environmental and social sustainability on different corporate aspects and decisions. This study is the only one to review the key topics on which papers published in Environment, Development and Sustainability are focused and can be largely used for sustainability practices. This study provides an overview of how the literature on sustainability has developed, as well as a summary of the most productive authors, along with countries, organizations, and journal sources. This offers an opportunity for future research to focus on this topic.
    Keywords:  Bibliometric analysis; Content analysis; Sustainability; VOSviewer
    DOI:  https://doi.org/10.1007/s10668-023-03067-6
  8. Am J Perinatol. 2023 Jun 26.
       OBJECTIVE:  This study aimed to conduct a bibliometric analysis of literature related to the diagnosis of chorioamnionitis (CAM) and to point out the current research progress, hotspots, and development trends of CAM research.
    STUDY DESIGN:  Literature on the diagnosis of CAM from the Web of Science Core Collection (WoSCC) between 2010 and 2022 was retrieved. CiteSpace, VOSviewer, and Online Analysis Platform (OALM) were used to draw maps of authors, articles, journals, institutions, countries/regions, and keywords.
    RESULTS:  A total of 312 articles were included, and the number of articles gradually increased over the study period. The author with the largest number of articles was Roberto Romero. The institution with the largest number of articles was Wayne State University School of Medicine, and the United States was the country that produced the largest number of articles. Analysis of keywords and outbreak words suggested that future research hotspots and trends may focus on early treatment of CAM and more precise, noninvasive, and more sensitive diagnoses.
    CONCLUSION:  In this study, visualization software and data information mining were innovatively used to conduct a bibliometric analysis of articles in the field of CAM diagnosis, and the current status, hotspots, and development of this field were obtained. Future research hotspots may be the precision diagnosis and treatment of CAM.
    KEY POINTS: · There is no bibliometric study on CAM diagnosis in the existing literature.. · The prediction of CAM diagnosis is an important topic to improve maternal and infant prognosis.. · Bibliometrics can effectively guide the direction of future research..
    DOI:  https://doi.org/10.1055/s-0043-1770366
  9. World Neurosurg. 2023 Jun 26. pii: S1878-8750(23)00867-7. [Epub ahead of print]
       BACKGROUND: Neuropathic pain (NeuP), the result of a lesion or disease of the somatosensory nervous system, is tricky to cure clinically. Mounting researches reveal that neuromodulation can safely and effectively ameliorate NeuP. The number of publications associated with neuromodulation and NeuP increases with time. However, bibliometric analysis on the field is rare. The present study aims to analyze trends and topics in neuromodulation and NeuP research by using a bibliometric method.
    METHOD: This study systematically collected the relevant publications on the Science Citation Index Expanded of Web of Science from January 1994 to January 17, 2023. CiteSpace software was used to draw and analyze corresponding visualization maps.
    RESULTS: A total of 1,404 publications were ultimately obtained under our specified inclusion criteria. The analysis showed that the focus of research on neuromodulation and NeuP had been developing steadily in recent years, with papers published in 58 countries/regions and 411 academic journals. The Journal of Neuromodulation and the author Lefaucheur JP published the most papers. The papers published in Harvard University and the United States contributed significantly. The cited keywords show that motor cortex stimulation, spinal cord stimulation, electrical stimulation, transcranial magnetic stimulation, and mechanism are the research hotspots in the field.
    CONCLUSION: The bibliometric analysis showed that the number of publications on neuromodulation and NeuP increasing rapidly, especially in the past 5 years. "Motor cortex stimulation," "electrical stimulation," "spinal cord stimulation," "transcranial magnetic stimulation" and "mechanism" catch the most attention among researchers in this field.
    Keywords:  CiteSpace(4); Neuropathic pain(5); bibliometrics(3); neuromodulation(2); visualized analysis(1)
    DOI:  https://doi.org/10.1016/j.wneu.2023.06.090
  10. Appl Biochem Biotechnol. 2023 Jun 29.
      Thermostability is considered a crucial parameter to evaluate the viability of enzymes in industrial applications. Over the past 31 years, many studies have been reported on the thermostability of enzymes. However, there is no systematic bibliometric analysis of publications on the thermostability of enzymes. In this study, 16,035 publications related to the thermostability of enzymes were searched and collected, showing an increasing annual trend. China contributed the most publications, while the United States had the highest citation count. International Journal of Biological Macromolecules is the most productive journal in the research field. Moreover, Chinese acad sci and Khosro Khajeh are the most active institutions and prolific authors in the field, respectively. Analysis of references with the strongest citation bursts and keyword co-occurrences, magnetic nanoparticles, metal-organic frameworks, molecular dynamics, and rational design are current hot spots and significant future research directions. This study is the first comprehensive bibliometric analysis summarizing trends and developments in enzyme thermostability research. Our findings could provide scholars with an understanding of the fundamental knowledge framework of the field and identify recent potential hotspots and research trends that could facilitate the discovery of collaboration opportunities.
    Keywords:  Bibliometric; Enzyme Thermostability; Magnetic Nanoparticles; Metal–Organic Frameworks; Rational Design
    DOI:  https://doi.org/10.1007/s12010-023-04615-6
  11. Heliyon. 2023 Jun;9(6): e17247
       Background: Gender disparity and hidden discrimination remained in the surgical subspecialties. This study aimed to explore the authorship gender composition in four high-impact colorectal surgery journals over the past two decades.
    Method: This cross-sectional study queried the Web of Science Core Collection database and PubMed (MEDLINE) for articles published in four high-impact colorectal surgery specialty journals between 2000 and 2021 (Database accessed at July 2022). Extracted data included authors' full names, institutions, year of publication and total citation numbers. Authors' genders were assigned via gendrize.io, a third-party name predictor tool.
    Results: 100,325 authorship records were included in the final analysis. 21.8% of writers were identified as female, an increase from 11.4% (95% CI, 9.4%-13.3%) in 2000 to 26.5% (95% CI, 25.6%-27.4%) in 2021. Female authorship has risen in all authorship types, but women physicians were less likely to be the last authors than the first (OR, 0.63; 95%CI, 0.6-0.67) or middle authors (OR, 0.57; 95%CI, 0.55-0.60). Female authorship has also increased substantially in different document types, but female authorships were less likely in editorials than original articles (OR, 0.76; 95%CI, 0.7-0.83) and reviews (OR, 0.83; 95%CI, 0.74-0.94). Compared with male physicians, females were more likely to author in publications with reportable funding, either as first authors (OR, 1.46; 95%CI, 1.12-1.78) or last authors (OR, 1.51; 95%CI, 1.22-1.89). Authorship varied geographically, and countries with the highest female authorship percentage were mainly in Europe and North America.
    Conclusion: Female authorship has grown substantially in colorectal surgery literature. However, female physicians were still underrepresented and less likely to assume senior or leading authorship roles.
    Keywords:  Authorship; Colorectal surgery; Gender disparity; Health care education
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e17247
  12. World J Otorhinolaryngol Head Neck Surg. 2023 Jun;9(2): 160-167
       Objective: The aim of this study was to identify and analyze the gender breakdown of first authorship contributing to the most-cited papers in the field of otolaryngology, with a goal of identifying trends in gender representation in publishing.
    Methods: The top 150 most-cited papers were identified using the Science Citation Index of the Institute for Scientific Information. Among the first authors, gender, h-index, percentage of first, last, and corresponding authorship positions, total publications, and citations were analyzed.
    Results: The majority of papers were in the English language, from the United States, of clinical nature, and on otologic topics. Eighty-one percent of papers (n = 122) had men who were first authors, although there was no difference in h-index score, authorship position, number of publications, citations, and average citations/year between men and women first authors. Upon subgroup analysis by decade (1950s-2010s), there was no difference in the number of articles by women first authors (P = 0.11); however, there was a statistically significant increase in the percentage of women authors (P = 0.001) in papers published later compared to those published earlier.
    Conclusions: While a promising number of women otolaryngologists are publishing high-powered articles, future initiatives to promote academic inclusivity of women should be considered.
    Keywords:  authorship; bibliometrics; citations; gender; otolaryngology; publications
    DOI:  https://doi.org/10.1002/wjo2.68
  13. Cureus. 2023 May;15(5): e39600
      The objective of this research is to conduct a comprehensive bibliometric analysis using the Web of Science Core Collection (WoSCC) to examine the current research topics and trends pertaining to stereotactic-based re-irradiation. A bibliometric search was conducted for re-irradiation-related literature published in English from the WoSCC database from 1991 to 2022, using VOSviewer to visualize the results. The extracted information comprises the publication year, overall citation count, average citation rate, keywords, and research domains. We conducted a literature review to identify trends in research on re-irradiation. A total of 19,891 citations were found in 924 qualifying papers that came from 48 different nations. The number of publications and citations has grown steadily since 2008 with the highest number of publications in the year 2018. Similarly, a substantial increase in the number of citations has increased since 2004 and the citation growth rate has been positive between 2004 and 2019 with a peak in 2013. The top authorship patterns were six authors (111 publications and 2498 citations), whereas the highest number of citations per publication was attained with an authorship pattern of 17 authors (C/P = 41.1). The collaboration patterns analysis showed that the largest proportion of publications emanated from the United States with 363 publications (30.9%), followed by Germany with 102 publications (8.7%), and France with 92 publications (7.8%). The majority of the analyzed studies were focused on the brain (30%), head and neck (13%), lung (12%), and spine (10%) and there have been emerging studies on the use of re-irradiation for lung, prostate, pelvic and liver utilizing stereotactic radiotherapy. The main areas of interest have changed over time and are now based on a multidisciplinary approach that integrates advanced imaging techniques, stereotactic treatment delivery, the toxicity of organs at risk, quality of life, and treatment outcomes.
    Keywords:  quality of life; radiotherapy toxicity; re-irradiation; stereotactic ablative radiotherapy fractionation; stereotactic radiotherapy (srt)
    DOI:  https://doi.org/10.7759/cureus.39600
  14. J Acad Ophthalmol (2017). 2022 Jul;14(2): e263-e270
      Background  The extent and impact of ophthalmology resident scholarly output is not well known. The authors aim to quantify scholarly activity of ophthalmology residents during residency and assess what factors may be associated with greater research productivity of these residents. Material and Methods  Ophthalmology residents who graduated in 2021 were identified from their respective program Web sites. Bibliometric data published by these residents between the beginning of their postgraduate year 2 (July 1, 2018) until 3 months after graduation (September 30, 2021) were captured through searches via PubMed, Scopus, and Google Scholar. The association of the following factors with greater research productivity numbers was analyzed: residency tier, medical school rank, sex, doctorate degree, type of medical degree, and international medical graduate status. Results  We found 418 ophthalmology residents from 98 residency programs. These residents published a mean (±standard deviation [SD]) number of 2.68 ± 3.81 peer-reviewed publications, 2.39 ± 3.40 ophthalmology-related publications, and 1.18 ± 1.96 first-author publications each. The mean (±SD) Hirsch index (h-index) for this cohort was 0.79 ± 1.17. Upon multivariate analysis, we discovered significant correlations between both residency tier and medical school rank and all bibliometric variables assessed. Pairwise comparisons revealed that residents from higher tier programs had greater research productivity numbers than those from lower tier programs. Conclusion  We obtained bibliometric standards for ophthalmology residents on a national scale. Residents who graduated from higher-ranked residency programs and medical schools possessed higher h-indices and published more peer-reviewed publications, ophthalmology-related articles, and first-author publications.
    Keywords:  bibliometric analysis; h-index; ophthalmology residency; research productivity
    DOI:  https://doi.org/10.1055/s-0042-1758565
  15. Front Pharmacol. 2023 ;14 1159286
      Background: The REFLECT phase-III trial has demonstrated the efficacy of lenvatinib in improving the overall survival of advanced hepatocellular carcinoma (HCC) patients, comparable to sorafenib. The rapidly evolving landscape of hepatocellular carcinoma therapy presents new avenues for lenvatinib. This study aims to provide a scientometric analysis of publications and predict research hotspots in this field. Methods: Relevant publications were sourced from the Web of Science Core Collection (WoSCC) database up until November 2022. The bibliometrix tool in R was employed for scientometric analysis and visualization. Results: A total of 879 publications from 2014 to 2022 were obtained from WoSCC that met the established criteria. These studies involved 4,675 researchers from 40 countries, with an average annual growth rate of 102.5%. The highest number of publications was from Japan, followed by China, Italy, and the United States. The largest proportion of studies, 14.0% (n = 123), was contributed by FUDAN UNIV. The studies were published in 274 journals, with CANCERS (n = 53) being the top journal, followed by FRONTIERS IN ONCOLOGY (n = 51) and HEPATOLOGY RESEARCH (n = 36). The top ten journals accounted for 31.5% of the 879 studies. The most prolific authors were Kudo M (n = 51), Hiraoka A (n = 43), and Tsuji K (n = 38). A total of 1,333 keywords were analyzed, with the present research hotspots being "immune checkpoint inhibitors," "prognosis," and "pd-1." Co-occurrence clustering analysis revealed the top keywords, authors, publications, and journals. Strong collaboration was identified in the field. Conclusion: This scientometric and visual analysis provides a comprehensive summary of the published articles on lenvatinib in HCC during 2014-2022, highlighting the research hotspots, knowledge domain, and frontiers. The results can provide insights into future research directions in this field.
    Keywords:  bibliometric; hepatocellular carcinoma; immunotherapy; lenvatinib; prognosis
    DOI:  https://doi.org/10.3389/fphar.2023.1159286
  16. Arthrosc Sports Med Rehabil. 2023 Jun;5(3): e793-e798
       Purpose: To identify the 25 most-cited articles on humeral avulsion of the glenohumeral ligament (HAGL) lesions and characterize them based on number of citations, citation density, source journal, year of publication, geographic origin, article type, and level of evidence.
    Methods: The Science Citation Index Expanded database was queried for all possible publications regarding HAGL lesions. The 25 most-cited articles from 1976 to 2021 relevant to the topic were selected for further analysis. Articles were characterized based on the number of citations, citation density, year of publication, source journal, country of origin, article type, article subtype, and level of evidence.
    Results: The number of citations for individual articles ranged from 21 to 182 (mean ± standard deviation: 44.72 ± 36.87). Ten countries contributed to the 25 most cited articles, with 14 of the 25 (56%) articles published in the United States. Furthermore, the top 25 cited articles were published in 9 journals, with the majority in Arthroscopy-The Journal of Arthroscopic and Related Surgery (n = 15, 60%). There were 15 (60%) articles classified as "Clinical," 9 (36%) as "Review/Expert Opinion," and 1 (4%) as "Basic Science." All clinical studies met the standard for level IV evidence.
    Conclusions: This bibliometric analysis provides a list of the 25 most cited articles related to HAGL lesions, providing a reference of impactful articles for medical educators. The lack of high level of evidence "Clinical" studies demonstrates that higher-quality research is needed to establish guidelines for the treatment and management of HAGL lesions.
    Clinical Relevance: A list of the 25 most-cited articles regarding recurrent glenohumeral instability can serve as a comprehensive reference for practitioners, educators, researchers, and orthopaedic trainees.
    DOI:  https://doi.org/10.1016/j.asmr.2023.04.006
  17. Medicine (Baltimore). 2023 Jun 30. 102(26): e34053
       PURPOSE: To take a systematic bibliometric analysis and generate the knowledge mapping of diabetic foot research, basing on big data from Web of Science Core Collection (WoSCC) database.
    METHODS: Two authors retrieved the WoSCC independently, to obtain publications in field of diabetic foot. CiteSpace was used to detect the co-occurrence relationships of authors, keywords, institutions, and countries/regions, co-citation relationships of authors, references, and journals, and distribution of WoS category.
    RESULTS: A total of 10,822 documents were included, with 39,541 authors contributed to this field. "Armstrong DG," "Lavery LA," and "Lipsky BA" are the top 3 productive authors, and "Armstrong DG," "Boulton AJM," and "Lavery LA" were most commonly cited. The United States, England and China are the most productive countries, and Univ Washington, Univ Manchester and Harvard Univ published the largest quantity of articles. "Diabetes Care," "Diabetic Med," and "Diabetologia" are the most frequently cited journals, providing the greatest knowledge base. Clustering analysis of keywords co-occurrence map presented the following hotspots: #1 diabetic wound healing, #2 diabetic polyneuropathy, #3 plantar pressure, #4 diabetic foot infection, #5 endovascular treatment, and #6 hyperbaric oxygen therapy.
    CONCLUSION: This study performed a global overview of diabetic foot research using bibliometric and visualization methods, which would provide helpful references for researchers focusing on this area to capture the future trend.
    DOI:  https://doi.org/10.1097/MD.0000000000034053
  18. Digit Health. 2023 Jan-Dec;9:9 20552076231184048
       Background: Artificial intelligence (AI) has promising applications in arthroplasty. In response to the knowledge explosion resulting from the rapid growth of publications, we applied bibliometric analysis to explore the research profile and topical trends in this field.
    Methods: The articles and reviews related to AI in arthroplasty were retrieved from 2000 to 2021. The Java-based Citespace, VOSviewer, R software-based Bibiometrix, and an online platform systematically evaluated publications by countries, institutions, authors, journals, references, and keywords.
    Results: A total of 867 publications were included. Over the past 22 years, the number of AI-related publications in the field of arthroplasty has grown exponentially. The United States was the most productive and academically influential country. The Cleveland Clinic was the most prolific institution. Most publications were published in high academic impact journals. However, collaborative networks revealed a lack and imbalance of inter-regional, inter-institutional, and inter-author cooperation. Two emerging research areas represented the development trends: major AI subfields such as machine learning and deep learning, and the other is research related to clinical outcomes.
    Conclusion: AI in arthroplasty is evolving rapidly. Collaboration between different regions and institutions should be strengthened to deepen our understanding further and exert critical implications for decision-making. Predicting clinical outcomes of arthroplasty using novel AI strategies may be a promising application in this field.
    Keywords:  Bibliometric analysis; arthroplasty; artificial intelligence; research trend
    DOI:  https://doi.org/10.1177/20552076231184048
  19. Educ Inf Technol (Dordr). 2023 Jun 07. 1-22
      The purpose of this research is to analyse the evolution and trends of research into digital pedagogy in higher education through the application of bibliometric analysis and systematic review of scientific output. For the bibliometric analysis, the built-in functions of WoS were used, including Analyze results and Citation report. The VOSviewer software was employed to construct bibliometric maps. The analysis focuses on studies about digitalisation, university education and education quality, three categories that are grouped around digital pedagogies and methodologies. The sample contains 242 scientific publications, including articles (65.7%), publications published in the United States (17.7%) and publications financed by the European Commission (3.71%). Barber, W., and Lewin, C., are the authors with the greatest impact. The scientific output forms three networks: the "social network" (2000-2010), the "digitalisation network" (2011-2015) and the "network of the expansion of digital pedagogy" (2016-2023). The most-mature research (2005-2009) concerns the integration of technologies in education. The research with the greatest impact (2020-2022) looks at digital pedagogy and its implementation during the situation created by COVID-19. This research shows that digital pedagogy has come a long way over the last twenty years, but it is at the same time a topical area today. The paper opens up future paths for research such as the development of more-flexible pedagogies that can be adapted to different pedagogical scenarios.
    Keywords:  Bibliometric analysis; Digital methodology; Digital pedagogy; Educational technology; Higher education; Networks of scientific output
    DOI:  https://doi.org/10.1007/s10639-023-11888-1
  20. J Eye Mov Res. 2022 ;15(4):
       BACKGROUND: For many years it has been studied how eye movements influence reading and learning ability. The objective of this study is to determine the relationships between the different publications and authors. As well as to identify the different areas of research ocular movement.; Methods: Web of Science was the database for the search of publications for the period 1900 to May 2021, using the terms: "Eye movement" AND "Academic achiev*". The analysis of the publication was performed using the CitNetExplorer, VOSviewer and CiteSpace software.; Results: 4391 publications and 11033 citation networks were found. The year with the most publications is 2018, a total of 318 publications and 10 citation networks. The most cited publication was "Saccade target selection and object recognition: evidence for a common attentional mechanism." published by Deubel et al. in 1999, with a citation index of 214. Using the Clustering function, nine groups were found that cover the main research areas in this field: neurological, age, perceptual attention, visual disturbances, sports, driving, sleep, vision therapy and academic performance.; Conclusion: Even being a multidisciplinary field of study, the topic with the most publications to date is the visual search procedure at the neurological level.
    Keywords:  citation network; eye movements; motor skills; oculomotor
    DOI:  https://doi.org/10.16910/jemr.15.4.4
  21. J Orthop Surg (Hong Kong). 2023 May-Aug;31(2):31(2): 10225536231181707
       BACKGROUND AND OBJECTIVE: As the amount of knowledge in literature continues to increase. Seeing research as a whole and determining its development and direction has become increasingly difficult. To overcome this challenge, new methods are needed. Among the methods developed, bibliometric methods that allow for evaluating research models from different perspectives and identifying collaborations stand out. This article it is aimed to identify the main research themes and trends, highlight the gaps in the literature, and explore the potential for research in this field.
    METHODS: Bibliometric analyses are conducted in databases that contain high-quality data. In this regard, the Web of Science Core Collection (WoS) was chosen in our study. The search was covered the years between 1982-2022. A total of 2556 articles. In our research, articles were examined in two sections. The first section provides an overview of articles on the intramedullary nailing. In the second stage, content analyses were conducted.
    RESULTS: A total of 2556 articles were published in 352 journals. The total number of authors is 8992, and the average citation per article is 18.87. The United States, China, and England are the top three countries. Based on the H-index most influential authors are Schemitsch EH and Bhandari M. The Injury-International Journal of the Care of the Injured journal has published 10.44% of all articles.
    CONCLUSION: Our study sheds light on the 40-year development dynamics of intramedullary nailing.
    Keywords:  bibliometrics; intramedullary nail; intramedullary nailing; scientific mapping; web of science core collection
    DOI:  https://doi.org/10.1177/10225536231181707
  22. World J Gastroenterol. 2023 Jun 14. 29(22): 3561-3573
       BACKGROUND: Recently, artificial intelligence (AI) has been widely used in gastrointestinal endoscopy examinations.
    AIM: To comprehensively evaluate the application of AI-assisted endoscopy in detecting different digestive diseases using bibliometric analysis.
    METHODS: Relevant publications from the Web of Science published from 1990 to 2022 were extracted using a combination of the search terms "AI" and "endoscopy". The following information was recorded from the included publications: Title, author, institution, country, endoscopy type, disease type, performance of AI, publication, citation, journal and H-index.
    RESULTS: A total of 446 studies were included. The number of articles reached its peak in 2021, and the annual citation numbers increased after 2006. China, the United States and Japan were dominant countries in this field, accounting for 28.7%, 16.8%, and 15.7% of publications, respectively. The Tada Tomohiro Institute of Gastroenterology and Proctology was the most influential institution. "Cancer" and "polyps" were the hotspots in this field. Colorectal polyps were the most concerning and researched disease, followed by gastric cancer and gastrointestinal bleeding. Conventional endoscopy was the most common type of examination. The accuracy of AI in detecting Barrett's esophagus, colorectal polyps and gastric cancer from 2018 to 2022 is 87.6%, 93.7% and 88.3%, respectively. The detection rates of adenoma and gastrointestinal bleeding from 2018 to 2022 are 31.3% and 96.2%, respectively.
    CONCLUSION: AI could improve the detection rate of digestive tract diseases and a convolutional neural network-based diagnosis program for endoscopic images shows promising results.
    Keywords:  Artificial intelligence; Bibliometric analysis; Endoscopy; Publications; Research trends
    DOI:  https://doi.org/10.3748/wjg.v29.i22.3561
  23. Work. 2023 Jun 22.
       BACKGROUND: Since the previous decade, researchers and academics have paid close attention to studying job embeddedness (JE), but the bibliometric examination of JE has not yet been explored.
    OBJECTIVE: This study aims to provide general information on the trends of the studies on JE as well as an overall perspective on the development of this topic by utilising a bibliometric analytic approach.
    METHOD: A bibliometric evaluation was conducted in the JE field since the first publication was documented in the Scopus database. The information retrieved examines 1572 JE papers from a variety of perspectives, including citation and publishing metrics.
    RESULTS: The research results pinpoint the most productive countries, universities, journals, authors, and JE articles. The study also classified the most important themes and offered some recommendations for further research.
    CONCLUSION: The study provided a snapshot of JE patterns and trajectories from 1993 to 2020, which can help academics and practitioners figure out the pattern and direction of future research. To the best of our knowledge, no other study examines the bibliographic data on JE and thus this work is one of the first contributions to the literature.
    Keywords:  Bibliometric analysis; embeddedness; publication metrics
    DOI:  https://doi.org/10.3233/WOR-220240
  24. Arch Comput Methods Eng. 2023 Apr 29. 1-31
      The machine learning (ML) paradigm has gained much popularity today. Its algorithmic models are employed in every field, such as natural language processing, pattern recognition, object detection, image recognition, earth observation and many other research areas. In fact, machine learning technologies and their inevitable impact suffice in many technological transformation agendas currently being propagated by many nations, for which the already yielded benefits are outstanding. From a regional perspective, several studies have shown that machine learning technology can help address some of Africa's most pervasive problems, such as poverty alleviation, improving education, delivering quality healthcare services, and addressing sustainability challenges like food security and climate change. In this state-of-the-art paper, a critical bibliometric analysis study is conducted, coupled with an extensive literature survey on recent developments and associated applications in machine learning research with a perspective on Africa. The presented bibliometric analysis study consists of 2761 machine learning-related documents, of which 89% were articles with at least 482 citations published in 903 journals during the past three decades. Furthermore, the collated documents were retrieved from the Science Citation Index EXPANDED, comprising research publications from 54 African countries between 1993 and 2021. The bibliometric study shows the visualization of the current landscape and future trends in machine learning research and its application to facilitate future collaborative research and knowledge exchange among authors from different research institutions scattered across the African continent.
    DOI:  https://doi.org/10.1007/s11831-023-09930-z
  25. J Pain Res. 2023 ;16 2101-2114
       Background: GABA-A receptors are the primary mediators of brain inhibitory neurotransmission. In the past years, many studies focused on this channel to decipher the pathogenesis of related diseases but lacked bibliometric analysis research. This study aims to explore the research status and identify the research trends of GABA-A receptor channels.
    Methods: Publications related to GABA-A receptor channels were retrieved from the Web of Science Core Collection from 2012 to 2022. After screening, the VOSviewer 1.6.18 and Citespace 5.8 R3 were used for bibliometric analysis from journals, countries, institutions, authors, co-cited references and keywords.
    Results: We included 12,124 publications in the field of GABA-A receptor channels for analysis. The data shows that although there was a slight decrease in annual publications from 2012 to 2021, it remained at a relatively high level. Most publications were in the domain of neuroscience. Additionally, the United States was the most prolific country, followed by China. Univ Toronto was the most productive institution, and James M Cook led essential findings in this field. Furthermore, brain activation, GABAAR subunits expression, modulation mechanism in pain and anxiety behaviors and GABA and dopamine were paid attention to by researchers. And top research frontiers were molecular docking, autoimmune encephalitic series, obesity, sex difference, diagnosis and management, EEG and KCC2.
    Conclusion: Taken together, academic attention on GABA-A receptor channels was never neglected since 2012. Our analysis identified key information, such as core countries, institutions and authors in this field. Molecular docking, autoimmune encephalitic series, obesity, sex difference, diagnosis and management, EEG and KCC2 will be the future research direction.
    Keywords:  CiteSpace; GABA; GABA-A receptor; VOSviewer; trends; visual analysis
    DOI:  https://doi.org/10.2147/JPR.S409380
  26. Healthcare (Basel). 2023 Jun 12. pii: 1725. [Epub ahead of print]11(12):
       BACKGROUND: This study employed bibliometric analysis to ascertain the research focus areas among a group of Mexican physicians affiliated with the Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE). ISSSTE, a healthcare institution catering to a diverse range of diseases, offers a distinctive perspective on the investigated specialties within the realm of health. The primary objective was to identify knowledge gaps in medical care disciplines through a comprehensive examination of scholarly publications.
    METHODS: We retrieved Scopus papers affiliated with "ISSSTE" and saved them as .CSV files. Subsequently, we employed VOSviewer, biblioshiny, and bibliometrix for bibliometric analysis. This enabled us to identify prominent institutions, prolific authors, highly cited researchers, and their respective affiliations.
    RESULTS: Our analysis identified 2063 publications; the specialty internal medicine accounted for the greatest proportion with 831 publications. Original papers accounted for 82% of the total, with 52% of them being written in Spanish. The majority of scientific output, 92%, originated from Mexico City. The annual production has steadily increased since 2010, peaking in 2021 with over 200 publications. However, papers on prevalent conditions, such as metabolic syndrome, received limited citations, and the L0 index (percentage of uncited items) for all papers is close to 60%. Scopus mislabeled one affiliation, and some cases show a low paper-to-author ratio of 0.5 Discussion: Additional concerns, such as honorary authorship due to excessive authors per paper, and the underlying causes of low citation rates in Mexican publications, warrant further examination. Moreover, our research emphasizes the urgency of bolstering research and development funding, which was consistently below 0.5% of GDP for the past four decades, falling short of legal mandates and international benchmarks. We endorse the establishment of robust research collectives in Latin America to address these challenges, foster regional scientific output, and transition from knowledge consumers to knowledge producers, thereby reducing dependence on foreign technology.
    Keywords:  ISSSTE; L0 index; Mexican scientific research; Scopus affiliation errors; bibliometric analysis; honorary authorship; manuscript writing
    DOI:  https://doi.org/10.3390/healthcare11121725
  27. Front Pharmacol. 2023 ;14 1190559
      Objectives: The study aims to explore the most influential countries, institutions, journals, authors, "research hotspots," and trends in the study of the mechanism of liver regeneration (MoLR) in the last 20 years using bibliometric analyses. Methods: The literature associated with the MoLR was retrieved from the Web of Science Core Collection on 11 October 2022. CiteSpace 6.1.R6 (64-bit) and VOSviewer 1.6.18 were used for bibliometric analyses. Results: A total of 18,956 authors from 2,900 institutions in 71 countries/regions published 3,563 studies in different academic journals on the MoLR. The United States was the most influential country. The University of Pittsburgh was the institution from which most articles on the MoLR were published. Cunshuan Xu published the most articles on the MoLR, and George K. Michalopoulos was the most frequently co-cited author. Hepatology was the journal in which most articles on the MoLR were published and the most frequently co-cited journal in this field. The research hotspots for the MoLR were origin and subsets of hepatocytes during LR; new factors and pathways in LR regulation; cell therapy for LR; interactions between liver cells in LR; mechanism of the proliferation of residual hepatocytes and trans-differentiation between cells; and prognosis of LR. The emerging topic was the mechanism of regeneration of a severely injured liver. Conclusion: Our bibliometric analyses provide (i) a comprehensive overview of the MoLR; (ii) important clues and ideas for scholars in this field.
    Keywords:  CiteSpace; VOSviewer; bibliometric; liver regeneration; mechanism
    DOI:  https://doi.org/10.3389/fphar.2023.1190559
  28. Front Microbiol. 2023 ;14 1208157
      Resistance of Helicobacter pylori (H. pylori) to antibiotics has reached alarming levels worldwide, and the efficacy of the H. pylori eradication treatment has decreased dramatically because of antibiotic resistance. To gain a more comprehensive understanding of the development status, research hotspots, and future trends related to H. pylori antibiotic resistance, we conducted a thorough retrospective analysis via the bibliometrics method. We searched the Science Citation Index Expanded of the Web of Science Core Collection for all pertinent articles on H. pylori antibiotic resistance from 2013 to 2022. R-bibliometrix, CiteSpace, and VOSviewer tools were utilized to depict statistical evaluations in order to provide an unbiased presentation and forecasts in the field. We incorporated a total of 3,509 articles related to H. pylori antibiotic resistance. Publications were inconsistent prior to 2017, but steadily increased after 2017. China generated the most papers and the United States of America received the most citations and the highest H-index. Baylor College of Medicine was the most influential institution in this field, with the highest number of publications and citations, as well as the highest H-index. Helicobacter was the most productive journal, followed by the World Journal of Gastroenterology and Frontiers in Microbiology. The World Journal of Gastroenterology had the highest citation. Graham, David Y was the most productive and cited author. Clarithromycin resistance, prevalence, gastric cancer, quadruple therapy, sequential therapy, 23S rRNA, whole genome sequencing, bismuth, and probiotics appeared with a high frequency in the keywords. The top keywords with the highest citation bursts were vonoprazan, RdxA, biofilm formation, and fatty acid chain. Our research illustrated a multi-dimensional facet and a holistic knowledge structure for H. pylori antibiotic resistance research over the past decade, which can serve as a guide for the H. pylori research community to conduct in-depth investigations in the future.
    Keywords:  Helicobacter pylori; antibiotic resistance; bibliometrics; microbiome; visualization
    DOI:  https://doi.org/10.3389/fmicb.2023.1208157
  29. Naunyn Schmiedebergs Arch Pharmacol. 2023 Jun 30.
      Glucagon-like peptide 1 receptor agonist (GLP-1RA) is a new class of glucose-lowing agents with the kidney benefit effect. This paper aims at finding the current state and hotspots of the research on GLP-1RA in kidney disease by using bibliometric methodologies and visualization maps to analyze publications and provide the direction for future studies on that topic. Literature information was obtained by retrieving the WoSCC database. Then, software like Microsoft Excel, VOSviewer, and CiteSpace was used to analyze and process obtained data. Bibliometric analysis and visualization of nations, authors, organizations, journals, keywords, and references were also done by VOSviewer and CiteSpace. A total of 991 publications written by 4747 authors from 1637 organizations in 75 countries on GLP-1RA in renal disease in Web of Science Core Collection were retrieved. The number of publications and citations kept growing from 2015 to 2022. The USA, Univ Copenhagen, and Rossing Peter are the leading country, organization, and author on this topic, respectively. All literature was published in 346 journals, and DIABETES OBESITY & METABOLISM is the journal with the most contributions. Meanwhile, most references are from DIABETES CARE. "Cardiovascular outcome" is the most frequent keyword in the total publications, and the reference cited most times is "Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes" by Marso SP. The topic of GLP-1RA in renal disease has attracted more and more attention all over the world. Existing studies are mainly about clinical use in patients with diabetes, and studies on the mechanism are lacking.
    Keywords:  Bibliometric analysis; Diabetic kidney disease; GLP-1RA; Non-diabetic kidney disease; Renal diseases
    DOI:  https://doi.org/10.1007/s00210-023-02575-6
  30. Arthrosc Sports Med Rehabil. 2023 Jun;5(3): e613-e622
       Purpose: To determine the most frequently cited articles relating to ice hockey since 2000 and conduct a bibliometric analysis of these publications.
    Methods: The Clarivate Web of Knowledge database was used to gather data and generate a list of publications relating to "ice hockey" on June 20, 2022. Articles were filtered by the total number of citations accrued and were included or excluded on the basis of relevance to ice hockey; no date of publication, language, or journal restrictions. After the 50 most highly cited articles were identified, articles published before the year 2000 were excluded to avoid bias. The information analyzed from each article included author name (first and last), publication year, country of origin, institutional affiliation (of the first and last author), journal name, research design, main research topic, competition level, and the level of evidence.
    Results: Ultimately, 46 studies were included in this analysis. The total number of citations was 8,267 times with an average of 179.7 citations per article. The most cited article was cited 926 times. The articles came from 5 different countries, with the United States and Canada comprising 27 and 13 articles, respectively. All articles were published in English. The American Journal of Sports Medicine published the greatest number of articles. The most studied topic was concussion/traumatic brain injury (n = 26). Professional hockey was the most studied level of competition (n = 15), while college followed (n = 13). Three institutions, University of Calgary, Dartmouth School of Medicine, and University of North Carolina at Chapel Hill were responsible for 32.6% of the top articles (n = 15).
    Conclusions: The majority of the most cited articles relating to ice hockey are cohort studies, review articles, and epidemiological studies originating from the United States or Canada. The majority of publications included in the analysis focused on concussion and traumatic brain injury prevalence, identification, diagnosis, outcomes, and prevention, as well as the most studied level of competition was professional, but the greatest number of participants arose from the youth and high school level.
    Level of Evidence: Level IV, cross-sectional study.
    DOI:  https://doi.org/10.1016/j.asmr.2023.02.014
  31. Medicine (Baltimore). 2023 Jun 30. 102(26): e34208
      There is currently no bibliometric study on teratomas in the literature. This study aims to analyze the published articles on teratomas to provide an overview of the subject, determine global productivity, and identify current research trends. Additionally, data on different components of scientific output (countries, journals, institutions, authors) were analyzed. A total of 4209 articles published on teratomas between 1980 and 2022 were analyzed using various bibliometric and statistical methods. Bibliometric network visualization maps were used to determine trending topics, citation analyses, and international collaborations. Spearman correlation coefficient was used for correlation analysis. The top 3 countries that made the most contributions to the literature were the USA (1041, 24.7%), Japan (501, 11.9%), and India (310, 7.3%). The top 3 active institutions were the University of California System (n = 78), University of London (64), and Harvard University (62). The top 3 productive journals were the Journal of Pediatric Surgery (n = 141), Pediatric Surgery International (n = 70), and Journal of Pediatric Surgery Case Reports (69). The most productive author was Ulbright TM. (n = 18). The most studied topics from past to present were ovarian cancer/ovarian teratoma/ovarian torsion, mature cystic teratoma/dermoid cyst, sacrococcygeal teratoma, germ cell tumors, immature teratoma, malignant transformation, mediastinal teratoma/mediastinum, neonate/newborn/infant, prenatal diagnosis, testis/testicular cancer/teratoma, ultrasonography/ultrasound, magnetic resonance imaging, chemotherapy, growing teratoma syndrome, surgery, retroperitoneal teratoma/retroperitoneum, laparoscopic surgery/laparoscopy, children/child, and fetal surgery/fetus. We identified trend research topics in the field of teratomas in recent years, including mature cystic teratoma, ovarian teratoma/neoplasm, ovarian cancer, ovarian torsion, growing teratoma syndrome, recurrence, pediatric, testicular cancer, anti-n-methyl-d-aspartate receptor encephalitis, immature teratoma, retroperitoneal, struma ovarii, and carcinoid. The research leadership in the development of teratoma literature was determined by countries with major economies such as the USA, Japan, India, the UK, China, Turkey, South Korea, and other European countries (France, Germany, Italy).
    DOI:  https://doi.org/10.1097/MD.0000000000034208
  32. Ann Med Surg (Lond). 2023 Jun;85(6): 3218-3225
      As a global pandemic, coronavirus disease 2019 (COVID-19) has led to a growing number of related research studies being published worldwide. However, there is no study on the bibliometric analysis of these Moroccan studies. This study aims to provide a general overview of COVID-19 studies in Morocco and may provide a direction for hot topics and future research trends.
    Method: The global literature about COVID-19 published between 2019 and 2022 was scanned in PubMed, the Web of Science collection database, Scopus, and two preprint platforms. 'COVID-19', 'Novel Coronavirus', '2019-nCoV', and 'SARS-CoV-2' were used as the keywords to reach the relevant publications. The VOS viewer was applied to perform the bibliometric analysis of these articles.
    Results: A total of 987 Moroccan publications on the topic of COVID-19 were retrieved. Of all these publications, 166 (61.9%) were original journal articles, 10 (3.7%) were review articles, 514 (8.38%) were letters and 56 (20.9%) were others, such as case reports, notes, or book chapters. Ten original articles (3.7%) had not yet been peer-reviewed and were retrieved from the preprint servers medRxiv and bioRxiv. The highest number of COVID-19 publications was published by Mohammed V University in Rabat (n=45, 16.8%), followed by Hassan II University (n=32, 11.9%) and Mohammed VI University of Health Sciences (n=29, 10.8%). The open-access format was the predominant publishing model (43.2%) and 92.9% were written in English. The main research lines identified in COVID-19 for Morocco are related to the pandemic's indirect effects: education (11.2%), mental health (6.3%), and the environment (6.3%).
    Conclusion: Moroccan institutions have made a profound contribution to COVID-19 research than that in other African countries, but lags behind compared to that in Arabic countries.
    Keywords:  Covid-19; bibliometrics; morocco
    DOI:  https://doi.org/10.1097/MS9.0000000000000643
  33. Cancers (Basel). 2023 Jun 18. pii: 3230. [Epub ahead of print]15(12):
      Tumor dormancy continues to be a research hotspot with numerous pressing problems that need to be solved. The goal of this study is to perform a bibliometric analysis of pertinent articles published in the twenty-first century. We concentrate on significant keywords, nations, authors, affiliations, journals, and literature in the field of tumor dormancy, which will help researchers to review the results that have been achieved and better understand the directions of future research. We retrieved research articles on tumor dormancy from the Web of Science Core Collection. This study made use of the visualization tools VOSviewer, CiteSpace, and Scimago Graphica, as visualization helps us to uncover the intrinsic connections between information. Research on tumor dormancy has been growing in the 21st century, especially from 2015 to the present. The United States is a leader in many aspects of this research area, such as in the number of publications, the number of partners, the most productive institutions, and the authors working in this field. Harvard University is the institution with the highest number of publications, and Aguirre-Ghiso, Julio A. is the author with the highest number of publications and citations. The keywords that emerged after 2017 were "early dissemination", "inhibition", "mechanism", "bone metastasis", and "promotion". We believe that research on tumor dormancy mechanisms and therapy has been, and will continue to be, a major area of interest. The exploration of the tumor dormancy microenvironment and immunotherapeutic treatments for tumor dormancy is likely to represent the most popular future research topics.
    Keywords:  bibliometric; immunotherapeutic treatments; mechanism; microenvironment; tumor dormancy
    DOI:  https://doi.org/10.3390/cancers15123230
  34. Innov High Educ. 2023 Mar 25. 1-24
      Despite originating in the tech industry, hackathons have now been adopted in a variety of domains. However, little is known about the status of hackathon literature within educational research. As the number of studies grows, it is essential to develop an understanding of the current state and identify prevalent topics and trends shaping the literature. Toward this goal, this study conducted a bibliometric analysis and scoping review on hackathon research in the field of education. A total of 249 documents written by 1,309 authors and published in 180 unique sources for the period 2014-2022 were identified. Collectively, the dataset amassed 1,312 citations with an average of 6.69 citations per document. The most prevalent subject areas were computer science, social sciences, engineering, medicine, and business. Word frequency analysis showed that "innovation" was the most occurring word, which represents the fundamental objective of hackathon events. The most influential work was the analysis of hackathons as an informal learning platform. Engineering education was the most trending topic while healthcare is an emerging research cluster. Overall, this study provides a better understanding of the hackathon literature and its research landscape in an educational setting.
    Keywords:  Bibliometric analysis; Education; Experiential learning; Hackathon; Innovation; Scoping review
    DOI:  https://doi.org/10.1007/s10755-023-09651-y
  35. Int Dent J. 2023 Jun 26. pii: S0020-6539(23)00092-8. [Epub ahead of print]
       OBJECTIVES: The aim of this analysis was to investigate the historical development, current status, and research hot spots related to maxillary protraction in the treatment of maxillary hypoplasia.
    METHODS: The term "TS = maxillary protraction" was used to search for articles in the Web of Science Core Collection at the library of Capital Medical University. The results were analysed using CiteSpace6.2.R1 software, including the examination of annual publication trends and analysis of author, country, institution, and keywords.
    RESULTS: A total of 483 papers were included in this study. The annual publications showed an overall increasing trend. The top 5 authors with the most published papers were Lorenzo Franchi, Tiziano Baccetti, Seung-Hak Baek, Paola Cozza, and U Hagg. The top 5 countries with the highest publication counts were the US, Turkey, South Korea, Italy, and China. The top 5 institutions in terms of the number of published papers were the University of Florence, the University of Michigan, Kyung Hee University, Seoul National University, and Gazi University. The top 3 journals with the most citations were the American Journal of Orthodontics and Dentofacial Orthopedics, Angle Orthodontist, and the European Journal of Orthodontics. Furthermore, "Maxillary protraction," "Class III malocclusion," and "Maxillary expansion" were the most common keywords.
    CONCLUSIONS: The effective age range for maxillary protraction has been expanded with the introduction of skeletal anchorage and the combination of maxillary expansion and protraction. Skeletal anchorage offers significant advantages over dental anchorage, but there is a need for further research to further substantiate its stability and safety. In recent years, the positive effects of maxillary protraction on the nasopharyngeal area have been well established, but its impact on the oropharyngeal area remains a topic of debate. Therefore, it is crucial to conduct further investigations into the effects of maxillary protraction on the oropharyngeal area and explore the factors that influence different outcomes.
    Keywords:  Airway; Anchorage; Bibliometric; Class Ⅲ malocclusion; Maxillary hypoplasia; Maxillary protraction
    DOI:  https://doi.org/10.1016/j.identj.2023.06.001
  36. Vaccines (Basel). 2023 Jun 19. pii: 1113. [Epub ahead of print]11(6):
       BACKGROUNDS: Melanoma is a malignant tumor that originates from melanocytes and is known for its aggressive behavior and high metastatic potential. In recent years, vaccine therapy has emerged as a promising approach for the treatment of melanoma, offering targeted and individualized immunotherapy options. In this study, we conducted a bibliometric analysis to assess the global research trends and impact of publications related to melanoma and vaccine therapy.
    METHODS: We retrieved relevant literature from the Web of Science database from the past decade (2013-2023) using keywords such as "melanoma", "vaccine therapy", and "cancer vaccines". We used bibliometric indicators including publication trends, citation analysis, co-authorship analysis, and journal analysis to evaluate the research landscape of this field.
    RESULTS: After screening, a total of 493 publications were included in the analysis. We found that melanoma and vaccine therapy have gained significant attention in the field of cancer immunotherapy, as evidenced by the numerous research output and increasing citation impact. The United States, China, and their organizations are the leading countries/institutes in terms of publication output, and collaborative research networks are prominent in this field. Clinical trials evaluating the safety and efficacy of vaccination treatment in melanoma patients are the focus of research.
    CONCLUSIONS: This study provide valuable insights into the novel research landscape of vaccine treatment of melanoma, which could inform future research directions and facilitate knowledge exchange among researchers in this field.
    Keywords:  cancer vaccine; melanoma; vaccine therapy
    DOI:  https://doi.org/10.3390/vaccines11061113
  37. Hum Vaccin Immunother. 2023 Jun 30. 2226584
      Although vaccination is regarded as one of the most significant achievements of public health, there also exists the phenomenon of vaccination hesitancy which refers to delay in acceptance or refusal of vaccination despite availability of vaccination services. In this study, we conducted a bibliometric analysis to provide a comprehensive overview of vaccination hesitancy research from 2013 to 2022. All related publications were retrieved from the Web of Science Core Collection Database. Information on annual publications, countries, organizations, journals, authors, keywords, and documents was analyzed adopting the bibliometix R-package, VOSviewer, and CiteSpace software. A total of 4042 publications were enrolled. The annual publications increased slightly before 2020 but had an extremely dramatic increase from 2020 to 2022. The United States contributed the most articles and had the greatest collaboration with other countries and organizations. The London School of Hygiene & Tropical Medicine was the most active institution. Vaccine was the most cited and influential journal while Vaccines was the most productive journal. It was Dube E who was the most productive authors with the highest h-index. The most frequent keywords were "vaccine hesitancy," "COVID-19," "SARS-CoV2," "immunization," "attitudes," and "willingness." Vaccination hesitancy to some extent hinders the achievement of global public health. The influencing factors vary across time, space, and vaccines. The COVID-19 pandemic and the development of COVID-19 vaccines have made this issue the focus of interest. The complexity and specific contexts of influencing factors of vaccination hesitancy require further study and will potentially be the focus of future research direction.
    Keywords:  CiteSpace; VOSviewer; Vaccination hesitancy; bibliometric analysis; visualization
    DOI:  https://doi.org/10.1080/21645515.2023.2226584
  38. Health Commun. 2023 Jun 27. 1-13
      This article presents a bibliometric analysis of research on COVID-19 health communication. We reviewed and analyzed 1,851 articles published in 170 peer-reviewed communication journals between January 2020 and November 2022, to identify key bibliometric information and major research topics in this rapidly expanding field of research. The distribution of countries indicates that the United States is the most productive country, and researchers from Spain, China and the United Kingdom also play an important role. Health Communication is the most influential journal in terms of research productivity and impact. The analysis of highly cited references demonstrates the interdisciplinary nature of this research field. The topics generated by structural topic modeling show that scholars have responded to a variety of issues in COVID-19 communication, encompassing different levels of health communication, the effects of information dissemination, the impact on the general public as well as vulnerable populations, health preventive behaviors and communication technologies. This study aims to enhance researchers' understanding of the current state of this research field and provide insights for future studies.
    DOI:  https://doi.org/10.1080/10410236.2023.2229093
  39. Diagnostics (Basel). 2023 Jun 19. pii: 2109. [Epub ahead of print]13(12):
      The applications of artificial intelligence (AI) in dementia research have garnered significant attention, prompting the planning of various research endeavors in current and future studies. The objective of this study is to provide a comprehensive overview of the research landscape regarding AI and dementia within scholarly publications and to suggest further studies for this emerging research field. A search was conducted in the Web of Science database to collect all relevant and highly cited articles on AI-related dementia research published in English until 16 May 2023. Utilizing bibliometric indicators, a search strategy was developed to assess the eligibility of titles, utilizing abstracts and full texts as necessary. The Bibliometrix tool, a statistical package in R, was used to produce and visualize networks depicting the co-occurrence of authors, research institutions, countries, citations, and keywords. We obtained a total of 1094 relevant articles published between 1997 and 2023. The number of annual publications demonstrated an increasing trend over the past 27 years. Journal of Alzheimer's Disease (39/1094, 3.56%), Frontiers in Aging Neuroscience (38/1094, 3.47%), and Scientific Reports (26/1094, 2.37%) were the most common journals for this domain. The United States (283/1094, 25.86%), China (222/1094, 20.29%), India (150/1094, 13.71%), and England (96/1094, 8.77%) were the most productive countries of origin. In terms of institutions, Boston University, Columbia University, and the University of Granada demonstrated the highest productivity. As for author contributions, Gorriz JM, Ramirez J, and Salas-Gonzalez D were the most active researchers. While the initial period saw a relatively low number of articles focusing on AI applications for dementia, there has been a noticeable upsurge in research within this domain in recent years (2018-2023). The present analysis sheds light on the key contributors in terms of researchers, institutions, countries, and trending topics that have propelled the advancement of AI in dementia research. These findings collectively underscore that the integration of AI with conventional treatment approaches enhances the effectiveness of dementia diagnosis, prediction, classification, and monitoring of treatment progress.
    Keywords:  Alzheimer’s disease; artificial intelligence; deep learning; dementia; machine learning
    DOI:  https://doi.org/10.3390/diagnostics13122109
  40. Multimed Tools Appl. 2023 Mar 02. 1-33
      With the spread of the deadly coronavirus disease throughout the geographies of the globe, expertise from every field has been sought to fight the impact of the virus. The use of Artificial Intelligence (AI), especially, has been the center of attention due to its capability to produce trustworthy results in a reasonable time. As a result, AI centric based research on coronavirus (or COVID-19) has been receiving growing attention from different domains ranging from medicine, virology, and psychiatry etc. We present this comprehensive study that closely monitors the impact of the pandemic on global research activities related exclusively to AI. In this article, we produce highly informative insights pertaining to publications, such as the best articles, research areas, most productive and influential journals, authors, and institutions. Studies are made on top 50 most cited articles to identify the most influential AI subcategories. We also study the outcome of research from different geographic areas while identifying the research collaborations that have had an impact. This study also compares the outcome of research from the different countries around the globe and produces insights on the same.
    Keywords:  Artificial intelligence; Bibliometric analysis; COVID-19; Computer science research; Coronavirus research; Publications; Research analysis
    DOI:  https://doi.org/10.1007/s11042-023-14642-4
  41. Environ Dev Sustain. 2023 May 07. 1-43
      The Sustainable Development Goals (SDGs) are a global appeal to protect the environment, combat climate change, eradicate poverty, and ensure access to a high quality of life and prosperity for all. The next decade is crucial for determining the planet's direction in ensuring that populations can adapt to climate change. This study aims to investigate the progress, challenges, opportunities, trends, and prospects of the SDGs through a bibliometric analysis from 2015 to 2022, providing insight into the evolution and maturity of scientific research in the field. The Web of Science core collection citation database was used for the bibliometric analysis, which was conducted using VOSviewer and RStudio. We analyzed 12,176 articles written in English to evaluate the present state of progress, as well as the challenges and opportunities surrounding the SDGs. This study utilized a variety of methods to identify research hotspots, including analysis of keywords, productive researchers, and journals. In addition, we conducted a comprehensive literature review by utilizing the Web of Science database. The results show that 31% of SDG-related research productivity originates from the USA, China, and the UK, with an average citation per article of 15.06. A total of 45,345 authors around the world have contributed to the field of SDGs, and collaboration among authors is also quite high. The core research topics include SDGs, climate change, Agenda 2030, the circular economy, poverty, global health, governance, food security, sub-Saharan Africa, the Millennium Development Goals, universal health coverage, indicators, gender, and inequality. The insights gained from this analysis will be valuable for young researchers, practitioners, policymakers, and public officials as they seek to identify patterns and high-quality articles related to SDGs. By advancing our understanding of the subject, this research has the potential to inform and guide future efforts to promote sustainable development. The findings indicate a concentration of research and development on SDGs in developed countries rather than in developing and underdeveloped countries.
    Graphical abstract:
    Keywords:  Bibliometric analysis; Environment; Sustainability; Sustainable development; Systematic literature review; Web of science
    DOI:  https://doi.org/10.1007/s10668-023-03225-w
  42. Medicine (Baltimore). 2023 Jun 30. 102(26): e34174
       BACKGROUND: Macrophages are closely related to the occurrence and development of depression, but there are few bibliometric studies on the role of macrophages in depression. We aim to examine the current state and frontier trends of the research on macrophages in depression from 2000 to 2022 in this study, so as to establish a new direction for follow-up research.
    METHODS: The literature scan covering the period 2000 to 2022 was performed on macrophages in depression, which were analyzed with Citespace 6.1.R2 and VOSviewer 1.6.18 after manual screening, including country publications, institutions, authors, journals, keywords, and references.
    RESULTS: This study included 387 papers in total. There has been an increase in the number of published papers since 2009. In terms of productivity, the United States and Ohio State University are the most productive countries and institutions. The most cited author is Maes M, cited 173 times, which has made a great contribution to the study of macrophages in depression. In terms of publications, Pariante CM, Drexhage HA. have the largest number, each author with five. Brain Behavior and Immunity is the most published and cited journals. The highest burst intensity keyword is microglia, and the highest burst intensity reference is Dowlati Y, 2010.
    CONCLUSION: Research hotspots and trends are analyzed and predicted in this study, which will facilitate the development of macrophage research in depression, so as to provide a reference for further research in this field.
    DOI:  https://doi.org/10.1097/MD.0000000000034174
  43. Medicine (Baltimore). 2023 Jun 30. 102(26): e34169
       BACKGROUND: Myocarditis can be classified into 2 categories: fulminant myocarditis (FM) and nonfulminant myocarditis. FM is the most severe type, characterized by its acute and explosive nature, posing a sudden and life-threatening risk with a high fatality rate. Limited research has been conducted on FM characteristics using cluster analysis. This study introduces the following-leading clustering algorithm (`) as a unique method and utilizes it to generate a dual map and timeline view of FM themes, aiming to gain a better understanding of FM.
    METHODS: The metadata were obtained from the Web of Science (WoS) database using an advanced search strategy based on the topic (TS= (("Fulminant") AND ("Myocarditis"))). The analysis comprised 3 main components: descriptive analytics, which involved identifying the most influential entities using CJAL scores and analyzing publication trends, author collaborations using the FLCA algorithm, and generating a dual map and timeline view of FM themes using the FLCA algorithm. The visualizations included radar plots divided into 4 quadrants, stacked bar and line charts, network charts, chord diagrams, a dual map overlay, and a timeline view.
    RESULTS: The findings reveal that the prominent entities in terms of countries, institutes, departments, and authors were the United States, Huazhong University of Science and Technology (China), Cardiology, and Enrico Ammirati from Italy. A dual map, based on the research category, was created to analyze the relationship between citing and cited articles. It showed that articles related to cells and clinical medicine/surgery were frequently cited by articles in the fields of general health/public/nursing and clinical medicine/surgery. Additionally, a visual timeline view was presented on Google Maps, showcasing the themes extracted from the top 100 cited articles. These visualizations were successfully and reliably generated using the FLCA algorithm, offering insights from various perspectives.
    CONCLUSION: A new FLCA algorithm was utilized to examine bibliometric data from 1989 to 2022, specifically focusing on FM. The results of this analysis can serve as a valuable guide for researchers, offering insights into the thematic trends and characteristics of FM research development. This, in turn, can facilitate and promote future research endeavors in this field.
    DOI:  https://doi.org/10.1097/MD.0000000000034169
  44. Front Physiol. 2023 ;14 1176894
      Background: The gut-kidney axis refers to the interaction between the gastrointestinal tract and the kidneys, and its disorders have become increasingly important in the development of kidney diseases. The aim of this study is to identify current research hotspots in the field of the gut-kidney axis from 2003 to 2022 and provide guidance for future research in this field. Methods: We collected relevant literature on the gut-kidney axis from the Web of Science Core Collection (WoSCC) database and conducted bibliometric and visualization analyses using biblioshiny in R-Studio and VOSviewer (version 1.6.16). Results: A total of 3,900 documents were retrieved from the WoSCC database. The publications have shown rapid expansion since 2011, with the greatest research hotspot emerging due to the concept of the "intestinal-renal syndrome," first proposed by Meijers. The most relevant journals were in the field of diet and metabolism, such as Nutrients. The United States and China were the most influential countries, and the most active institute was the University of California San Diego. Author analysis revealed that Denise Mafra, Nosratola D. Vaziri, Fouque, and Denis made great contributions in different aspects of the field. Clustering analysis of the keywords found that important research priorities were "immunity," "inflammation," "metabolism," and "urinary toxin," reflecting the basis of research in the field. Current research frontiers in the field include "hyperuricemia," "gut microbiota," "diabetes," "trimethylamine n-oxide," "iga nephropathy," "acute kidney injury," "chronic kidney disease," "inflammation," all of which necessitate further investigation. Conclusion: This study presents a comprehensive bibliometric analysis and offers an up-to-date outlook on the research related to the gut-kidney axis, with a specific emphasis on the present state of intercommunication between gut microbiota and kidney diseases in this field. This perspective may assist researchers in selecting appropriate journals and partners, and help to gain a deeper understanding of the field's hotspots and frontiers, thereby promoting future research.
    Keywords:  VOSviewer; bibliometric analysis; gut microbiota; gut-kidney axis; kidney disease
    DOI:  https://doi.org/10.3389/fphys.2023.1176894
  45. J Robot Surg. 2023 Jun 28.
       OBJECTIVES: Robotic pancreaticoduodenectomy (RPD) has garnered significant research attention in the last decade. However, no bibliometric studies have been conducted on this field yet. Therefore, the aim of this study is to provide an up-to-date analysis of the current state of research, as well as future trends and hotspots in RPD, through a bibliometric analysis.
    MATERIALS AND METHODS: We conducted a thorough search of all literature related to RPD in the Web of Science Core Collection (WoSCC). We then analyzed this literature for a variety of factors, including authorship, country of origin, institutional affiliations, and keywords. To visualize our findings, we utilized Citespace 6.1.R3, which enabled us to create network visualization maps, perform cluster analysis, and extract burst words.
    RESULTS: A total of 264 articles were retrieved. Zureikat is the author with the largest contribution in this field, and Surgical Endoscopy and Other International Techniques is the journal with the largest number of papers in this field. The United States is the core research country in this field. The University of Pittsburgh is the most productive institution. According to the data, outcome, pancreas fistula, definition, risk factor, stay, survival, learning curve and experience are recognized as research hotspots in this field.
    CONCLUSIONS: This study is the first bibliometric study in the field of RPD. Our data will help us better understand the development trend of the field, and determine research hotspots and research directions. The research results provide practical information for other scholars to understand key directions and cutting-edge information.
    Keywords:  Bibliometric analysis; Minimally Invasive Pancreatoduodenectomy; Robot
    DOI:  https://doi.org/10.1007/s11701-023-01658-z
  46. Educ Inf Technol (Dordr). 2023 Apr 03. 1-32
      Blended learning (BL) applications, which are defined as a combination of online and face-to-face education processes and created with the strongest aspects of various teaching approaches, have attracted increasing attention particularly in recent years with the effect of the pandemic. Although blended learning studies, which have a wide range of content and variety of applications in the literature, have been examined by content analysis in many scientific studies, bibliometric studies that provide a comprehensive review of studies on BL and reveal a general map of scientific studies are extremely limited. The purpose of this research is to conduct a systematic analysis of BL studies around the world and to reveal general research trends by bibliometric method. In the scope of the research, 4,059 publications searched in the Scopus database between the years 1965-2022 were analyzed by VOSviewer and Leximancer software; the publications were examined from aspects such as year, subject, fund, citation, journal, country, common word, etc. An analysis of the research results reveals that studies on BL have increased in number in the literature since 2006; it has been found that the fields of social sciences, computer, medicine and engineering come to the forefront in the categorization of publications by subject, and the USA, UK, China and Australia are the most cited countries. As revealed by the findings of common word analysis, the studies mostly focus on the use of technology during the pandemic, current trends in education and technology, online learning environment and learner characteristics, teaching approaches, social media, motivation and medical education. Furthermore, it is understood that the most common terms in abstracts-keywords and titles of the studies reflect the learning process, the learner, the classroom environment, the model adopted, the system designed and medical education.
    Keywords:  Bibliometrics; Blended learning; Citation analysis; Common word analysis; Flipped learning; Hybrid education
    DOI:  https://doi.org/10.1007/s10639-023-11754-0
  47. Healthcare (Basel). 2023 Jun 06. pii: 1669. [Epub ahead of print]11(12):
      This research aims to provide an overview of the growing number of scientific literature publications related to Physical Activity and Healthy Habits. A bibliometric analysis between 1990 and 2022 in the Web of Science was carried out, following the bibliometric analysis law, using Microsoft Excel and VosViewer Software for analysis and data processing. A total of 276 documents (262 primary studies and 14 revisions) related to the topic under study were located. The results reveal an exponential growth of scientific production by 48% between 2006 and 2022. Public Environmental Occupational Health, Kaprio, J., and the USA were the knowledge field, author, and country most productive, respectively. A great thematic diversity was found related to the most used keywords by the authors, such as "physical activity", "health habits", "exercise", and "obesity". Thus, the research related to this theme is really in an exponential phase, with great interest in the importance of physical activity and healthy habits, implying practical decisions in policies to develop programs to promote physical activity and healthy habits.
    Keywords:  exercise; obesity; physical fitness; quality of life; scientometrics
    DOI:  https://doi.org/10.3390/healthcare11121669
  48. Environ Dev Sustain. 2023 May 19. 1-25
      Global cities play a significant role in world economy as they serve as key hubs of economic activity and trade. These cities are centers of innovation, finance, culture, and commerce, attracting businesses and entrepreneurs from all over the world. They are characterized by their openness, diversity, and their ability to attract and retain talent. This paper includes a bibliometric analysis of the structure of global cities through examining the literature on global cities, including the document type, country/territory distribution, institution distribution, geographical distribution of authors, specially most active authors and their interests or research areas, relationships between principal authors and more relevant journals, and the research hot spots. The input data consists of journal articles archived by the Web of Science from 1991 to 2023, and the analysis is performed using SciMAT and VOS Viewer. The result of this paper would provide valuable insights into the state of research on this topic, including who is conducting research, where it is being conducted, what types of publications are being produced, and which themes are having the most impact on the field. Such an analysis would be useful for researchers, policymakers, and other stakeholders interested in understanding the role of global cities in the world economy.
    Graphical abstract:
    Keywords:  Bibliometric review; Data analysis; Global cities; SciMAT; Web of science
    DOI:  https://doi.org/10.1007/s10668-023-03255-4
  49. Work. 2023 Jun 23.
       BACKGROUND: The use of new technologies boosted Industry 4.0, making processes more sophisticated and considering the interaction between physical production systems and workers. But these new technologies also intervene in the worker's quality of life (QoL), that is, we need to know if the industry of the future is changing the scenario of the present.
    OBJECTIVES: This study aims to identify trends in study topics related to QoL in Industry 4.0.
    METHODS: A bibliometric mapping analysis was performed without temporal delimitation in the Scopus, Web of Science and PubMed databases.
    RESULTS: The results show that: (i) the publications most aligned with the theme are from 2016 onwards; (ii) the greatest growth in publications on the subject occurred between the years 2019, 2020 and 2021; (iii) the Journal Sustainability was the most relevant journal on the subject in recent years; (iv) Turkey stood out as the most cited country in the field of study; (v) there are collaboration networks between authors in several countries, including Denmark, Italy and Poland; (vi) with the analysis of the thematic map, it is possible to identify which themes are the motor, specialized, emerging, missing, or basic from the research field and; (vii) the sub-themes that appeared the most in the surveys were work environment, impact of industry 4.0, robots, health and well-being, digitalization and job satisfaction.
    CONCLUSION: In addition to being a relevant source of information, where readers find future thematic trends in the field of research, it is hoped that the contributions of this study will provide insights for researchers, academics and society in general.
    Keywords:  Occupational health; healthy work environment; job satisfaction; workplace
    DOI:  https://doi.org/10.3233/WOR-220637
  50. Front Surg. 2023 ;10 1187223
       Introduction: Arthroplasty is the final treatment option for maintaining mobility and quality of life in many primary degenerative and (post-) traumatic joint diseases. Identification of research output and potential deficits for specific subspecialties may be an important measure to achieve long-term improvement of patient care in this field.
    Methods: Using specific search terms and Boolean operators, all studies published since 1945 to the subgroups of arthroplasty listed in the Web of Science Core Collection were included. All identified publications were analysed according to bibliometric standards, and comparative conclusions were drawn regarding the scientific merit of each subgroup.
    Results: Most publications investigated the subgroups of septic surgery and materials followed by approach, navigation, aseptic loosening, robotic and enhanced recovery after surgery (ERAS). In the last 5 years, research in the fields of robotic and ERAS achieved the highest relative increase in publications In contrast, research on aseptic loosening has continued to lose interest over the last 5 years. Publications on robotics and materials received the most funding on average while those on aseptic loosening received the least. Most publications originated from USA, Germany, and England, except for research on ERAS in which Denmark stood out. Relatively, publications on aseptic loosening received the most citations, whereas the absolute scientific interest was highest for the topic infection.
    Discussion: In this bibliometric subgroup analysis, the primary scientific outputs focused on septic complications and materials research in the field of arthroplasty. With decreasing publication output and the least financial support, intensification of research on aseptic loosening is urgently recommended.
    Keywords:  arthroplasty; bibliometric; joint replacement; research patterns; subgroup analysis
    DOI:  https://doi.org/10.3389/fsurg.2023.1187223
  51. Front Neurol. 2023 ;14 1171167
       Background: The growing interest suggests that the widespread application of radiomics has facilitated the development of neurological disease diagnosis, prognosis, and classification. The application of artificial intelligence methods in radiomics has increasingly achieved outstanding prediction results in recent years. However, there are few studies that have systematically analyzed this field through bibliometrics. Our destination is to study the visual relationships of publications to identify the trends and hotspots in radiomics research and encourage more researchers to participate in radiomics studies.
    Methods: Publications in radiomics in the field of neurological disease research can be retrieved from the Web of Science Core Collection. Analysis of relevant countries, institutions, journals, authors, keywords, and references is conducted using Microsoft Excel 2019, VOSviewer, and CiteSpace V. We analyze the research status and hot trends through burst detection.
    Results: On October 23, 2022, 746 records of studies on the application of radiomics in the diagnosis of neurological disorders were retrieved and published from 2011 to 2023. Approximately half of them were written by scholars in the United States, and most were published in Frontiers in Oncology, European Radiology, Cancer, and SCIENTIFIC REPORTS. Although China ranks first in the number of publications, the United States is the driving force in the field and enjoys a good academic reputation. NORBERT GALLDIKS and JIE TIAN published the most relevant articles, while GILLIES RJ was cited the most. RADIOLOGY is a representative and influential journal in the field. "Glioma" is a current attractive research hotspot. Keywords such as "machine learning," "brain metastasis," and "gene mutations" have recently appeared at the research frontier.
    Conclusion: Most of the studies focus on clinical trial outcomes, such as the diagnosis, prediction, and prognosis of neurological disorders. The radiomics biomarkers and multi-omics studies of neurological disorders may soon become a hot topic and should be closely monitored, particularly the relationship between tumor-related non-invasive imaging biomarkers and the intrinsic micro-environment of tumors.
    Keywords:  bibliometrics; deep learning; glioblastoma (GBM); multi-omics study; nervous system diseases; radiomics
    DOI:  https://doi.org/10.3389/fneur.2023.1171167
  52. Digit Health. 2023 Jan-Dec;9:9 20552076231183550
      In recent years, there has been an increase in the scientific production of youth soccer. However, a panoramic map of research on this subject does not exist. The aim of this study was to identify global research trends in youth soccer over time, among the main levels of analysis: sources, authors, documents, and keywords. The bibliometric software Biblioshiny was used to analyze 2606 articles in Web of Science (WoS) published between 2012 and 2021. The main conclusion is that US and UK scholars dominate the research; the topics of research are changing with the real needs, and research on the topic of performance has been of interest to scholars; talent identification and development, performance, injury prevention, and concussion are the studies of interest to scholars in this area. This finding, which offers a global picture of youth soccer research over time, can help future research in this or similar domains.
    Keywords:  WoS; Youth soccer; bibliometrix; biliometric analysis
    DOI:  https://doi.org/10.1177/20552076231183550
  53. Front Cardiovasc Med. 2023 ;10 1180792
       Background: Myocardial ischemia/reperfusion injury (MIRI) refers to the more severe damage that occurs in the previously ischemic myocardium after a short-term interruption of myocardial blood supply followed by restoration of blood flow within a certain period of time. MIRI has become a major challenge affecting the therapeutic efficacy of cardiovascular surgery.
    Methods: A scientific literature search on MIRI-related papers published from 2000 to 2023 in the Web of Science Core Collection database was conducted. VOSviewer was used for bibliometric analysis to understand the scientific development and research hotspots in this field.
    Results: A total of 5,595 papers from 81 countries/regions, 3,840 research institutions, and 26,202 authors were included. China published the most papers, but the United States had the most significant influence. Harvard University was the leading research institution, and influential authors included Lefer David J., Hausenloy Derek J., Yellon Derek M., and others. All keywords can be divided into four different directions: risk factors, poor prognosis, mechanisms and cardioprotection.
    Conclusion: Research on MIRI is flourishing. It is necessary to conduct an in-depth investigation of the interaction between different mechanisms and multi-target therapy will be the focus and hotspot of MIRI research in the future.
    Keywords:  bibliometric analysis; mechanism; multi-target therapy; myocardial infarction; myocardial ischemia/reperfusion injury; reperfusion therapy
    DOI:  https://doi.org/10.3389/fcvm.2023.1180792
  54. Int J Environ Res Public Health. 2023 Jun 16. pii: 6156. [Epub ahead of print]20(12):
      Babesia infection is a tick-borne protozoan disease associated with significant veterinary, economic, and medical importance. This infection affects many hosts, ranging from wild to domestic animals and including man. All vertebrates serve as potential carriers due to the huge diversity of the species. Babesiosis has been associated with severe economic loss in livestock production, especially in cattle farming, and is also a major public health concern in man, which could be fatal. The infection is usually opportunistic, ranging from asymptomatic to symptomatic, usually in immunocompromised subjects or under conditions of stressful management. This study was designed to uncover trends in relation to publication growth and further explore research output regarding babesiosis from data indexed in the WoS. The WoS is the only platform used to map publications on Babesia infection. The search term "babesiosis" or "Babesia infection" was used to extract articles published across the study period from 1982 to 2022. The inclusion criteria were restricted to only articles for the analysis. The results from the search query showed that a total of 3763 articles were published during the study period with an average of 91.70 ± 43.87 articles annually and an average total citation (n = 1874.8). An annual growth rate of 2.5% was recorded during the study period. The year 2021 had the highest number of published articles (n = 193, 5.1%) and citations (n = 7039). The analysis of the most relevant keywords and titles showed that infection (n = 606, 16.1%), babesiosis (n = 444, 11.7%), and Babesia (n = 1302, 16%) were the most relevant keyword plus (ID), author keyword (DE), and title, respectively. The common conceptual framework analysis through K-means clustering showed two clusters comprising 4 and 41 elements, respectively. The United States of America is the top-performing country in terms of article production (n = 707, 20.8%) and the leading funder for babesiosis research, with two of its agencies ranked at the top. These are the Department of Health and Human Services (n = 254, 6.7%) and the National Institute of Health (n= 238,6.3%). Igarashi I. is the top-performing author (n = 231, 6.1%), while Veterinary Parasitology is ranked the top journal (n = 393, 10.4%) in terms of babesiosis publications. Overall, an increase in publications was observed in the study period, with significant output from developed nations.
    Keywords:  Web of Science (WoS); babesiosis; bibliometric; cosmopolitan; tick-borne
    DOI:  https://doi.org/10.3390/ijerph20126156
  55. Zhongguo Zhong Yao Za Zhi. 2023 Jun;48(11): 3110-3117
      This study aimed to investigate the development status of traditional Chinese medicine(TCM) intervention in psoriasis in recent ten years, analyze the research hotspots, and summarize the development trends to provide reference materials for scholars in this field. Taking the available literature related to the field of TCM intervention in psoriasis as the research object, the trends, contents, and source publications were statistically analyzed based on bibliometrics. The research cooperation and co-occurrence of keywords in this field were studied by the knowledge map analysis method based on CiteSpace. The total number of Chinese papers was 2 993 and English papers 285. In terms of publication trend, the annual publication of English papers was low but showed an obvious upward trend, while the increase in Chinese papers fluctuated and tended to be flat. In terms of the content of Chinese papers published, TCM ranked first according to the discipline(2 415). In English papers, the number of publications in pharmacology and pharmaceutical science was the highest(87). Literature source analysis showed that the Chinese and English journals with the most publications were China Journal of Traditional Chinese Medicine and Pharmacy and Evidence Based Complementary and Alternative Medicine, respectively. Beijing University of Chinese Medicine published the most dissertations in China(99). The authors with the most publications in Chinese and English were LI Bin(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine) and LU Chuan-jian(Guangdong Hospital of Traditional Chinese Medicine). As revealed by the CiteSpace analysis of the research cooperation network, there were four mature and stable core teams in this field, but the cooperation intensity between different teams was weak. According to the keywords co-occurrence knowledge graph constructed by CiteSpace, the current hot keywords in this field are as follows: psoriasis, blood-heat syndrome, blood-stasis syndrome, fire needle, blood-dryness type, imiquimod, TCM bath, etiology and pathogenesis, cytokines, cupping therapy, etc. In summary, Chinese scholars have conducted active exploration and research in the field of TCM intervention in psoriasis in recent ten years. The overall development trend is good, and the breadth and depth of the research are constantly extending. It is suggested that relevant research should be free from discipline restrictions and strive for interdisciplinary integration.
    Keywords:  CiteSpace; bibliometrics; hotspot analysis; knowledge map; psoriasis; research progress; traditional Chinese medicine
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20230224.501
  56. Ann Agric Environ Med. 2023 Jun 26. pii: 166680. [Epub ahead of print]30(2): 352-363
       INTRODUCTION AND OBJECTIVE: In recent years, load monitoring and analysis have become increasingly important in athletic training. The aim of this study was to provide a background for businesses and institutes to prepare for the implementation of load training and analysis in sports training, utilizing visual analysis of CiteSpace (CS) software.
    MATERIAL AND METHODS: A total of 169 original publications were obtained from Web of Science using a comprehensive list for analysis with the CS scientometrics program. The parameters included range (2012-2022), visualization (display of completely integrated networks), precise collection criteria (top 10%), node form (institution, author, area, reference cited; referenced author, key words, and journal), and trimming (pathfinder, slice network).
    RESULTS: Visual analysis of load monitoring and analysis for use in athletic training showed that 'questionnaire' was the most popular topic area in 2017 with 51 citations, while 'training programmes' emerged as a new area of study with 8 citations. In 2021 and 2022, the terms 'energy expenditure', 'responses', 'heart rate', and 'validity' gained popularity, increasing from a strength of 1.81 to 1.1. Liverpool John Moores University was the top institution, collaborating with 14 other organizations. The leading authors in this field were Close, Graeme L., and Gastin, Paul B. Most publications were found in the 'SPORTS MED' journal, with authors primarily based in the United Kingdom, the United States, and Australia.
    CONCLUSIONS: The findings of the study highlight the potential frontiers of load training analysis in the research and management of sports, emphasizing the importance of preparing businesses and institutes for the implementation of load training, and analysis in athletic training.
    Keywords:  CiteSpace; energy; load monitoring; sports; sustainability
    DOI:  https://doi.org/10.26444/aaem/166680
  57. Medicine (Baltimore). 2023 Jun 30. 102(26): e34244
      Sarcopenic obesity is a complex condition characterized by the combination of age-related loss of muscle mass and high levels of adiposity, or body fat. Up to 30% of older adults may be affected by this condition, and its prevalence varies by gender, race, and ethnicity. It can lead to postural instability and reduced physical activity, increasing the risk of falls, fractures, and functional limitations. The purpose of this study was to evaluate scientific articles on sarcopenic obesity using statistical methods and to assess the topic from a novel perspective. The Web of Science database publications on sarcopenic obesity published between 1980 and 2023 were analyzed using statistical and bibliometric methods. Spearman correlation coefficient was used in correlation analyses. A nonlinear cubic model regression analysis was performed to forecast the number of publications in the following years. Using keyword network visualization maps, recurrent topics, and relationships were identified. Between 1980 and 2023, the search criteria yielded 1013 publications on geriatric malnutrition. Nine hundred of these (articles, reviews, and meeting abstracts) were included in the analysis. Since 2005, the volume of published materials on the topic has increased dramatically and is continuing to rise. The USA and South Korea were the most active nations, Scott D and Prado CMM were the most active authors, and Osteoporosis International was the most active journal on the subject. This research has shown that countries with higher economic development tend to produce more research on the issue, and the number of publications on the topic will rise in the upcoming years. It is an important research topic in an aging society and needs to be further researched. We believe this article may aid clinicians and scientists in comprehending global efforts to combat sarcopenic obesity.
    DOI:  https://doi.org/10.1097/MD.0000000000034244
  58. Zhongguo Zhong Yao Za Zhi. 2023 Jun;48(12): 3394-3403
      This study retrieved Croci Stigma related literature from CNKI, Wanfang, VIP, and Web of Science database, and used bibliometrics and CiteSpace 6.1.R2 software to analyze the published Croci Stigma related articles in Chinese and English from 2000 to 2022. The authors, research institutions, and keywords were visualized and analyzed, and the current status and development trend of Croci Stigma research was summarized by combining the information extraction methods. A total of 1 846 Chinese articles and 2 703 English articles were screened out and included. The results showed a generally steady increase in the number of Croci Stigma related articles. The results of the visualization analysis showed that there were more collaborations between researcher teams and major research institutions in English articles than Chinese articles. The Chinese articles was mainly published by China Pharmaceutical University, and most of the inter-institutional collaborations occurred in neighboring regions. The English articles was mainly published by Iranian institutions, and most of the cooperation occurred within the country, with less transnational cooperation. Keywords analysis showed that the research on Croci Stigma was mainly focused on chemical compositions, pharmacological effects, mechanisms, quality control, etc. It was predicted that the future research hotspots of Croci Stigma would mainly focus on pharmacological mechanism and clinical efficacy. The current research related to Croci Stigma still needs to be developed, cooperation should be strengthened, and more in-depth research should be conducted.
    Keywords:  CiteSpace; Croci Stigma; bibliometrics; knowledge map; visualization analysis
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20230226.503
  59. Rev Med Chil. 2022 Sep;pii: S0034-98872022000901188. [Epub ahead of print]150(9): 1188-1194
       BACKGROUND: Despite recent initiatives and efforts, gender inequality still exists in medicine and academia. There is a higher proportion of male authors in international scientific publications.
    AIM: To compare the proportion of female and male authors in the scientific publications of the main medical journals in Chile.
    MATERIAL AND METHODS: We reviewed 1,643 Scientific articles published between 2015 and 2020 in two medical journals from Chile. Three authors analyzed the title, abstract, and authors of all published articles, recording the sex of the first author, co-authors, and corresponding author.
    RESULTS: The reviewed articles had a mean of 5.3 authors and there was a significant difference between men and women (a mean of 2.8 men and 2.4 women; p < 0.001). Forty-six percent (n = 761) of the articles had a female first author. In a higher proportion of papers, men completed both positions (1st and corresponding author) simultaneously.
    CONCLUSIONS: There are fewer female authors in scientific publications. Chile is one of the countries with a high rate of gender gap in the world. The underrepresentation of women in academia is an example of this.
    DOI:  https://doi.org/10.4067/S0034-98872022000901188
  60. AI Ethics. 2023 Mar 07. 1-31
       Introduction: Advances in Artificial Intelligence (AI) offer new Information Technology (IT) opportunities in various applications and fields (industry, health, etc.). The medical informatics scientific community expends tremendous effort on the management of diseases affecting vital organs making it a complex disease (lungs, heart, brain, kidneys, pancreas, and liver). Scientific research becomes more complex when several organs are simultaneously affected, as is the case with Pulmonary Hypertension (PH), which affects both the lungs and the heart. Therefore, early detection and diagnosis of PH are essential to monitor the disease's progression and prevent associated mortality.
    Method: The issue addressed relates to knowledge of recent developments in AI approaches applied to PH. The aim is to provide a systematic review through a quantitative analysis of the scientific production concerning PH and the analysis of the networks of this production. This bibliometric approach is based on various statistical, data mining, and data visualization methods to assess research performance using scientific publications and various indicators (e.g., direct indicators of scientific production and scientific impact).
    Results: The main sources used to obtain citation data are the Web of Science Core Collection and Google Scholar. The results indicate a diversity of journals (e.g., IEEE Access, Computers in Biology and Medicine, Biology Signal Processing and Control, Frontiers in Cardiovascular Medicine, Sensors) at the top of publications. The most relevant affiliations are universities from United States of America (Boston Univ, Harvard Med Sch, Univ Oxford, Stanford Univ) and United Kingdom (Imperial Coll London). The most cited keywords are "Classification", "Diagnosis", "Disease", "Prediction", and "Risk".
    Conclusion: This bibliometric study is a crucial part of the review of the scientific literature on PH. It can be viewed as a guideline or tool that helps researchers and practitioners to understand the main scientific issues and challenges of AI modeling applied to PH. On the one hand, it makes it possible to increase the visibility of the progress made or the limits observed. Consequently, it promotes their wide dissemination. Furthermore, it offers valuable assistance in understanding the evolution of scientific AI activities applied to managing the diagnosis, treatment, and prognosis of PH. Finally, ethical considerations are described in each activity of data collection, treatment, and exploitation to preserve patients' legitimate rights.
    Keywords:  Artificial intelligence; Bibliometrics; Deep learning; Ethics; GDPR; Machine learning; Medical informatics; Pulmonary hypertension
    DOI:  https://doi.org/10.1007/s43681-023-00267-8
  61. Univers Access Inf Soc. 2023 Mar 21. 1-14
      This study offers a comprehensive analysis of COVID-19 research in education. A multi-methods approach was used to capture the full breadth of educational research. As such, a bibliometric analysis, structural topic modeling, and qualitative synthesis of top papers were combined. A total of 4,201 articles were retrieved from Scopus, mostly published from 2019 to 2021. In this work special attention is paid to analyzing and synthesizing findings about: (i) status of research about COVID-19 regarding frequencies, venues, publishing countries, (ii) identification of main topics in the COVID-19 research, and (iii) identification of the major themes in most cited articles and their impact on the educational community. Structural topic modeling identified three main groups of topics that related to education in general, moving to online education, or diverse topics (e.g., perceptions, inclusion, medical education, engagement and motivation, well-being, and equality). A deeper analysis of the papers that received most attention revealed that problem understanding was the dominating theme of papers, followed by challenges, impact, guidance, online migration, and tools and resources. A vast number of papers were produced. However, thoughtful, well-planned, and meaningful research was hard to conceptualize or implement, and a sense of urgency led to a deluge of research with thin contributions in a time of dire need to genuine insights.
    DOI:  https://doi.org/10.1007/s10209-023-00989-w
  62. Qual Quant. 2023 May 02. 1-30
      This paper surveys the extant literature on machine learning, artificial intelligence, and deep learning mechanisms within the financial sphere using bibliometric methods. We considered the conceptual and social structure of publications in ML, AI, and DL in finance to better understand the research's status, development, and growth. The study finds an upsurge in publication trends within this research arena, with a bit of concentration around the financial domain. The institutional contributions from USA and China constitute much of the literature on applying ML and AI in finance. Our analysis identifies emerging research themes, with the most futuristic being ESG scoring using ML and AI. However, we find there is a lack of empirical academic research with a critical appraisal of these algorithmic-based advanced automated financial technologies. There are severe pitfalls in the prediction process using ML and AI due to algorithmic biases, mostly in the areas of insurance, credit scoring and mortgages. Thus, this study indicates the next evolution of ML and DL archetypes in the economic sphere and the need for a strategic turnaround in academics regarding these forces of disruption and innovation that are shaping the future of finance.
    Keywords:  Artificial intelligence; Bibliometric analysis; Conceptual structure; Deep learning; Machine learning; Social structure
    DOI:  https://doi.org/10.1007/s11135-023-01673-0
  63. J Acad Ophthalmol (2017). 2022 Jan;14(1): e133-e140
      Importance  San Francisco Match publishes no data on the research output of matched applicants to an ophthalmology residency. Objective  The aim of this study was to examine the temporal trends in publication volume by medical students who successfully matched into a top ophthalmology residency. Methods  This retrospective case series compared all residents in the top 30 ophthalmology residency programs from the class of 2022 and 2017. Publication volume from before September 15th of the residents' fourth year of medical school was recorded using PubMed and Google Scholar. We recorded total number of publications (any authorship), first/second author publications, and ophthalmology-specific publications. Using Welch's t -test, publication volumes were statistically compared against all others. Results  One-hundred sixty-one residents from the class of 2022 and 145 residents from the class of 2017 were included. Total publications per matched applicant (mean ± standard deviation) were 3.04 ± 0.35 for the class of 2022 and 1.67 ± 0.23 for the class of 2017. Mean publications in ophthalmology journals were 1.07 ± 0.20 (2022) and 0.58 ± 0.13 (2017); mean first author publications were 1.00 ± 0.13 (2022) and 0.64 ± 0.11 (2017) and mean second author publications were 0.70 ± 0.10 (2022) and 0.37 ± 0.06 (2017). Research productivity in all four metrics (total, ophthalmology journals, first author, and second author publications) was significantly higher for the class of 2022 than the class of 2017 ( p  = 0.001; p  = 0.03; p  = 0.03; p  = 0.02, respectively) supporting the trend of increasing research output among students. Applicants with PhD degrees had statistically more total and first author publications in 2017 ( p  = 0.01; p  = 0.045), but only more first author publications in 2022 ( p  = 0.01). International applicants produced significantly more total publications in 2022 ( p  < 0.001). Conclusions  Overall, after a 5-year period, the authors found matched applicants had significantly increased publications compared with those at the beginning of the period. We also identified several applicant factors that may have variable effects on research publication. This analysis emphasizes the growing importance of research in the match process and can help future applicants navigate the ophthalmology match.
    Keywords:  San Francisco Match; medical school; ophthalmology residency; publications; research productivity
    DOI:  https://doi.org/10.1055/s-0042-1746423
  64. Iowa Orthop J. 2023 ;43(1): 7-13
       Background: The Ruth Jackson Orthopaedic Society awards the Jacquelin Perry, MD Resident Research Grant and RJOS/Zimmer Biomet Clinical/Basic Science Research Grant to female orthopedic surgeons, intending to aid women in the progression and completion of their orthopedic research and bolster their pursuit or current career in academic orthopedic surgery. The impact of these grants has not yet been studied. The purpose of this study is to determine the percentage of scholarship/grant-winners who went on to publish the findings of their research, pursue academic positions, and currently hold positions of leadership in the field of orthopedic surgery.
    Methods: The titles of the winning research projects were searched in PubMed, Embase, and/or Web of Science to ascertain publication status. For each award recipient, the number of publications prior to the award year, number of publications after the award year, total number of publications, and H-index were calculated. Each award recipient was searched online through the websites of their employment and social media pages to determine their residency institution, whether they pursued a fellowship, the number of fellowships they pursued, their subspecialty within orthopedics, their current job, and whether they are in academic or private practice.
    Results: Of the fifteen Jacquelin Perry, MD Resident Research Grant winners, 73.3% of awarded research projects have since been published. 76.9% of award winners currently work in an academic setting and are affiliated with a residency program, and 0% currently hold leadership positions in orthopedic surgery. Of the eight winners of the RJOS/Zimmer Biomet Clinical/Basic Science Research Grant, 25% have published the findings of their awarded grant. 87.5% of award winners currently work in academics, and 75% hold leadership positions in orthopedic surgery.
    Conclusion: Our results show that many of the winners of the Jacquelin Perry, MD Resident Research Grant and RJOS/Zimmer Biomet Clinical/ Basic Science Research Grant have published their research findings, continued research within the field of orthopedic surgery, and pursued academic careers and leadership positions. Many of the barriers to career progression and entry into orthopedic surgery that women and underrepresented groups face could be overcome through more grant opportunities and mentorship. Level of Evidence: V.
    Keywords:  diversity; equity; inclusion; orthopedic surgery
  65. Scientometrics. 2023 Jun 05. 1-17
      The COVID-19 pandemic triggered unprecedented scientific efforts worldwide and launched several initiatives to promote international cooperation. Because international scientific collaborations between high-income countries (HICs) and low- and middle-income countries (LMICs) are not always balanced, analyzing research leadership helps to understand the global dynamics of knowledge production during COVID-19. In this study, we focused on HIC-LMIC collaborations on COVID-19 research in 469,937 scientific publications during the first 2 years of the pandemic (2020-2021). Co-authorship and authors' affiliation were used to identify international collaborations, according to country income level. The leadership analysis considered the countries of the first and last authors of publications. The results show that (i) most publications with international collaborations (49.3%) involved researchers from HICs and LMICs; (ii) collaborative research between HICs and LMICs addressed relevant public health needs; (iii) HIC-LMIC collaborations were primarily led by researchers from the United States, China, the United Kingdom, and India; (iv) most HIC-LMIC publications (44%) had shared leadership, with research interests linked to national expertise and global interests. This study contributes to the analysis of research collaborations on COVID-19 and sheds light on North-South relations in the production and dissemination of scientific knowledge.
    Keywords:  Bibliometrics; COVID-19; Leadership; Low- and middle-income countries; Networks; Research collaboration
    DOI:  https://doi.org/10.1007/s11192-023-04754-x
  66. Diagn Interv Imaging. 2023 Jun 22. pii: S2211-5684(23)00147-X. [Epub ahead of print]
      
    Keywords:  Bibliometrics; Citations; Equality; Publications; Radiology
    DOI:  https://doi.org/10.1016/j.diii.2023.06.010
  67. Curr Psychol. 2023 Jun 03. 1-24
      This study aims to select the physiological and neurophysiological studies utilized in advertising and to address the fragmented comprehension of consumers' mental responses to advertising held by marketers and advertisers. To fill the gap, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework was employed to select relevant articles, and bibliometric analysis was conducted to determine global trends and advancements in advertising and neuromarketing. The study selected and analyzed forty-one papers from the Web of Science (WoS) database from 2009-2020. The results indicated that Spain, particularly the Complutense University of Madrid, was the most productive country and institution, respectively, with 11 and 3 articles. The journal Frontiers in Psychology was the most prolific, with eight articles. The article "Neuromarketing: The New Science of Consumer Behavior" had the most citations (152 T.Cs). Additionally, the researchers discovered that the inferior frontal and middle temporal gyri were associated with pleasant and unpleasant emotions, respectively, while the right superior temporal and right middle frontal gyrus was connected to high and low arousal. Furthermore, the right prefrontal cortex (PFC) and left PFC were linked to withdrawal and approach behaviors. In terms of the reward system, the ventral striatum played a critical role, while the orbitofrontal cortex and ventromedial PFC were connected to perception. As far as we know, this is the first paper that focused on the global academic trends and developments of neurophysiological and physiological instruments used in advertising in the new millennium, emphasizing the significance of intrinsic and extrinsic emotional processes, endogenous and exogenous attentional processes, memory, reward, motivational attitude, and perception in advertising campaigns.
    Keywords:  Advertising; Bibliometric analysis; Consumers’ responses; Neuromarketing; PRISMA; WoS database
    DOI:  https://doi.org/10.1007/s12144-023-04812-w
  68. J Med Internet Res. 2023 Jun 29. 25 e46328
       BACKGROUND: Previous studies on COVID-19 scholarly articles have primarily focused on bibliometric characteristics, neglecting the identification of institutional actors that cite recent scientific contributions related to COVID-19 in the policy domain, and their locations.
    OBJECTIVE: The purpose of this study was to assess the online citation network and knowledge structure of COVID-19 research across policy domains over 2 years from January 2020 to January 2022, with a particular emphasis on geographical frequency. Two research questions were addressed. The first question was related to who has been the most active in policy engagement with science and research information sharing during the COVID-19 pandemic, particularly in terms of countries and organization types. The second question was related to whether there are significant differences in the types of coronavirus research shared among countries and continents.
    METHODS: The Altmetric database was used to collect policy report citations of scientific articles for 3 topic terms (COVID-19, COVID-19 vaccine, and COVID-19 variants). Altmetric provides the URLs of policy agencies that have cited COVID-19 research. The scientific articles used for Altmetric citations are extracted from journals indexed by PubMed. The numbers of COVID-19, COVID-19 vaccine, and COVID-19 variant research outputs between January 1, 2020, and January 31, 2022, were 216,787, 16,748, and 2777, respectively. The study examined the frequency of citations based on policy institutional domains, such as intergovernmental organizations, national and domestic governmental organizations, and nongovernmental organizations (think tanks and academic institutions).
    RESULTS: The World Health Organization (WHO) stood out as the most notable institution citing COVID-19-related research outputs. The WHO actively sought and disseminated information regarding the COVID-19 pandemic. The COVID-19 vaccine citation network exhibited the most extensive connections in terms of degree centrality, 2-local eigenvector centrality, and eigenvector centrality among the 3 key terms. The Netherlands, the United States, the United Kingdom, and Australia were the countries that sought and shared the most information on COVID-19 vaccines, likely due to their high numbers of COVID-19 cases. Developing nations, although gaining quicker access to COVID-19 vaccine information, appeared to be relatively isolated from the enriched COVID-19 pandemic content in the global network.
    CONCLUSIONS: The global scientific network ecology during the COVID-19 pandemic revealed distinct types of links primarily centered around the WHO. Western countries demonstrated effective networking practices in constructing these networks. The prominent position of the key term "COVID-19 vaccine" demonstrates that nation-states align with global authority regardless of their national contexts. In summary, the citation networking practices of policy agencies have the potential to uncover the global knowledge distribution structure as a proxy for the networking strategy employed during a pandemic.
    Keywords:  COVID-19; COVID-19 research; WHO; World Health Organization; altmetrics; citation analysis; government policy report; online citation network; policy domains
    DOI:  https://doi.org/10.2196/46328
  69. J Acad Ophthalmol (2017). 2022 Jul;14(2): e147-e152
      Introduction  Positive and negative associations between prior publications and future research productivity is described in other fields, but no such analysis exists for ophthalmology. We conducted a study to determine characteristics of residents exhibiting research productivity during residency. Methods  Using San Francisco Match and Program Web sites, a roster of ophthalmology residents in 2019 to 2020 was compiled, and publication data was collected via PubMed and Google Scholar on a random sample of 100 third-year residents. Results  The median number of publications generated by ophthalmology residents before residency is 2 (range 0-13). Thirty-seven, 23, and 40 residents had zero, one, and two or more papers published during residency, respectively, with a median of 1 (range 0-14). On univariate analysis, compared with residents who published zero or one paper, those who published ≥ 2 were more likely to have more preresidency publications (odds ratio [OR] 1.30; p  = 0.005), attend a top-25 ranked residency program by multiple metrics including Doximity reputation (OR 4.92; p  < 0.001), and have attended a top-25 ranked medical school program by U.S. News and World Report (OR 3.24; p  = 0.03). However, on adjusted analyses, the only factor that remained significant for predicting publications in residency was whether the residency program attended was top 25 ranked (OR 3.54; p  = 0.009). Discussion/Conclusion  With the advent of the United States Medical Licensing Examination Step 1 pass/fail system, greater emphasis will be placed on other metrics, including research. This is the first benchmark analysis examining factors predictive of publication productivity in ophthalmology residents. Our study suggests that the residency program attended, not the medical school attended or prior publication history, plays an influential role in the number of publications produced during residency, highlighting the importance of factors to support research on the institutional level, such as mentorship and funding, rather than historical factors in research productivity by the resident.
    Keywords:  medical school; publications; research productivity; residency
    DOI:  https://doi.org/10.1055/s-0042-1750021
  70. Drug Discov Today. 2023 Jun 27. pii: S1359-6446(23)00193-9. [Epub ahead of print] 103677
      Alzheimer's disease (AD) has no effective treatment, although antibody drugs targeting beta-amyloid, mainly aducanumab, have produced useful clinical results. Biomarkers can be used to determine drug regimens effectively and to monitor the effects of drugs. A concept in which biomarkers reflect disease states is emerging. Although several AD biomarker studies have been reported, measurement methods and target molecules are still being validated, and various biomarkers are being explored. This study analyzed trends in research on AD biomarkers using bibliometric methods, revealing an exponential increase in research reports in this field, with the US most active in research. Analysis of the 'Burst' biomarkers using CiteSpace revealed that networks centered on authors, rather than networks among countries, drive new research trends in this area.
    Keywords:  Alzheimer’s disease; biomarker research; dementia
    DOI:  https://doi.org/10.1016/j.drudis.2023.103677
  71. Foods. 2023 Jun 16. pii: 2394. [Epub ahead of print]12(12):
      The potential of paraprobiotics and postbiotics to be used as beneficial agents for human health has caused an effort by the scientific community to gather information about the bioactivity of these compounds and production methods. Understanding the evolution of scientific research in this area of study is important to understand the future perspectives and the main bottlenecks of scientific and technological development involving these compounds. In this scenario, this review work used a bibliometric analysis tool intending to improve the scientific documentation, bringing information and communicating the results to the scientific community through the quantitative analysis of the current literature, available in one of the main databases, the Web of Science, also providing recent information on the evolution and future perspectives in the field of paraprobiotic and postbiotic development. The results of this study showed that the main studies discuss the bioactivity of these compounds. Concerning the development of functional foods, there is a need for extensive research on production methods and the interaction of these compounds with food. However, it concluded that much still needs to be studied to prove the claims of bioactivity, especially when used for the development of functional foods.
    Keywords:  bibliometric analysis; bioactivity; food safety; probiotics
    DOI:  https://doi.org/10.3390/foods12122394
  72. Stud Health Technol Inform. 2023 Jun 29. 305 5-9
      Artificial intelligence (AI) tends to emerge as a relevant component of medical care, previously reserved for medical experts. A key factor for the utilization of AI is the user's trust in the AI itself, respectively the AIt's decision process, but AI-models are lacking information about this process, the so-called Black Box, potentially affecting usert's trust in AI. This analysis' objective is the description of trust-related research regarding AI-models and the relevance of trust in comparison to other AI-related research topics in healthcare. For this purpose, a bibliometric analysis relying on 12985 article abstracts was conducted to derive a co-occurrence network which can be used to show former and current scientific endeavors in the field of healthcare based AI research and to provide insight into underrepresented research fields. Our results indicate that perceptual factors such as "trust" are still underrepresented in the scientific literature compared to other research fields.
    Keywords:  Artificial Intelligence; Black-Box; Trust; bibliometric analysis
    DOI:  https://doi.org/10.3233/SHTI230409
  73. Ann Intensive Care. 2023 Jun 27. 13(1): 56
       BACKGROUND: Females and ethnic minorities are underrepresented in the first and senior authorships positions of academic publications. This stems from various structural and systemic inequalities and discrimination in the journal peer-review process, as well as educational, institutional, and organizational cultures.
    METHODS: A retrospective bibliometric study design was used to investigate the representation of gender and racial/ethnic groups in the authorship of critical care randomized controlled trials in 12 high-impact journals from 2000 to 2022.
    RESULTS: In the 1398 randomized controlled trials included in this study, only 24.61% of the first authors and 16.6% of the senior authors were female. Although female authorship increased during the study period, authorship was significantly higher for males throughout (Chi-square for trend, p < 0.0001). The educational attainment [χ2(4) = 99.2, p < 0.0001] and the country of the author's affiliated institution [χ2(42) = 70.3, p = 0.0029] were significantly associated with gender. Male authorship was significantly more prevalent in 10 out of 12 journals analyzed in this study [χ2(11) = 110.1, p < 0.0001]. The most common race/ethnic group in our study population was White (85.1% women, 85.4% males), followed by Asians (14.3% females, 14.3% males). Although there was a significant increase in the number of non-White authors between 2000 and 2022 [χ2(22) = 77.3, p < 0.0001], the trend was driven by an increase in non-White male and not non-White female authors. Race/ethnicity was significantly associated with the country of the author's affiliated institution [χ2(41) = 1107, p < 0.0001] but not with gender or educational attainment.
    CONCLUSIONS: Persistent gender and racial disparities in high-impact medical and critical care journals underscore the need to revise policies and strategies to encourage greater diversity in critical care research.
    Keywords:  Authorship; Critical care; Ethnic disparities; Gender disparities; RTCs; Racial disparities
    DOI:  https://doi.org/10.1186/s13613-023-01157-2
  74. J Acad Ophthalmol (2017). 2022 Jul;14(2): e238-e245
      Background  Few studies have evaluated associations between ophthalmology trainee characteristics and performance with postgraduate research productivity. Purpose  This article evaluates factors associated with post-residency research productivity among U.S. ophthalmology graduates. Methods  Publicly available information of residents graduating between 2009 and 2014 from 30 randomly selected U.S. ophthalmology programs was collected from June to September 2020. Differences in publications between the 5 years post-residency and pre-residency/residency period were used as metrics of productivity. Residents with incomplete records were excluded. Results  A total of 758 of 768 residents, 306 females (40.4%) and 452 males (59.6%), met inclusion criteria. The mean (standard deviation [SD]) number of pre-residency publications was 1.7 (4.0), residency was 1.3 (2.2), and post-residency was 4.0 (7.3). Mean (SD) H-index was 4.2 (4.9). Top-ranked residency ( p  = 0.001), Alpha Omega Alpha (AOA) medical honor status ( p  = 0.002), U.S. medical school graduates ( p  < 0.001), and academic career ( p  < 0.001) were all associated with higher pre-/post-residency mean publication difference. Pursuing fellowship training also was associated with higher total publications ( p  < 0.001). Of all pre-residency degrees, PhD had the greatest odds of high postgraduate publications (defined as > 4). There was a positive correlation between both pre-residency/residency and post-residency publications (rho = 0.441; p  < 0.001) and between mean difference of pre-residency/post-residency publications for residents at a program and that program's Doximity rank (rho = 0.497; p  < 0.001). Multivariate logistic regression revealed, academic career choice (odds ratio [OR] = 3.38; p  < 0.001), Heed fellowship (OR = 3.12; p  = 0.031), > 2 residency publications (OR = 2.89; p  < 0.001), AOA status (OR = 2.0; p  = 0.004), and top-ranked residency programs (OR = 1.89; p  = 0.007), had greatest odds of > 4 postgraduation publications. Conclusion  Higher post-residency productivity was associated with multiple factors, with choice of an academic career, Heed fellowship, and residency productivity playing key roles.
    Keywords:  Doximity rank; ophthalmology; publication; research productivity; residency
    DOI:  https://doi.org/10.1055/s-0042-1756124
  75. Univers Access Inf Soc. 2023 Mar 20. 1-23
      Nowadays social media usage has increased drastically among the stakeholders of higher educational institutions. The COVID-19 pandemic has suddenly increased the surge of social media users due to the forced implementation of online pedagogy and travel restrictions. The research study presented in this paper attempted to analyze social media usage in higher education. The data were collected from primary and secondary sources with the help of leading research databases, survey questionnaires, the Delphi method, and brainstorming sessions. Statistical tools and analytic techniques incorporated in the study included bibliometric analysis, word cloud, co-occurrence network, thematic map, thematic evolution, co-word analysis, country-wise analysis along with collaboration network, statistical survey, mind mapping, and analytic hierarchy process. The study justified the aspects of social media usage in the higher educational environment. It was found that the research fraternity around the globe focused more on understanding the aspects of social media and higher education during the trying times of the Coronavirus crisis. The maximum impact of social media usage on higher education was found to be from teaching-learning and discussions, and public relations and networking. It was also found that social networking platforms like WhatsApp, YouTube, Facebook (Meta), LinkedIn, Instagram, and Twitter were very common among the stakeholders of higher education. This study is of huge importance because it can help in paving the way to strategize remedial measures for increasing positivity and minimizing the negativity of social media usage in institutions of higher education across the world.
    Supplementary Information: The online version contains supplementary material available at 10.1007/s10209-023-00988-x.
    Keywords:  Analytic hierarchy process; Bibliometric analysis; COVID-19 pandemic; Higher education; Social media
    DOI:  https://doi.org/10.1007/s10209-023-00988-x
  76. Bioengineering (Basel). 2023 Jun 19. pii: 731. [Epub ahead of print]10(6):
      The objective of the research was to examine the scientific literature concerning restorative materials with bioactive properties for the purpose of covering dentin. Searches were performed in various databases including MEDLINE, Scopus, Web of Science, Cochrane Library, Lilacs/BBO, and Embase. Inclusion criteria involved studies that utilized the terms "dentin" and "bioactive", along with "ion-releasing", "smart materials", "biomimetic materials" and "smart replacement for dentin". The information extracted included the title, authors, publication year, journal and the country of affiliation of the corresponding author. The studies were categorized based on their study design, type of material, substrate, analytical method, and bioactivity. A total of 7161 records were recovered and 159 were included for data extraction. Most of the publications were in vitro studies (n = 149), testing different types of materials in sound dentine (n = 115). Most studies were published in Dental Materials (n = 29), and an increase in publications could be observed after the year 2000. Most of the articles were from the USA (n = 34), followed by Brazil (n = 28). Interfacial analysis was the most investigated (n = 105), followed by bond strength (n = 86). Bioactivity potential was demonstrated for most tested materials (n = 148). This review presents insights into the current trends of bioactive materials development, clearly showing a severe lack of clinical studies.
    Keywords:  bibliometrics; dental material; dentin; dentistry; smart materials; tooth demineralization
    DOI:  https://doi.org/10.3390/bioengineering10060731
  77. Environ Dev Sustain. 2023 Mar 16. 1-17
      The knowledge graph based on research papers can accurately identify and present the latest developments in scientific and technological (S&T) innovation and is of great significance for supporting strategic decision-making relating to S&T innovation in undeveloped areas. Based on the international research papers produced in Gansu Province during the 13th Five-Year Plan period (2016-2020), five metrics, including the number and characteristics of papers, co-authors, main publications and their fields, major supporting institutions, and main research areas, are established herein. The results indicate that: (i) the total of 29,951 papers were published, which is about 2.89 times that in 2010-2015; (ii) Gansu Province collaborated with 149 countries/regions globally; (iii) the top 5 journals in terms of the number of papers were Medicine, Scientific Reports, RSC Advances, Science of the Total Environment, and Physical Reviews D; (iv) the funding sources were mainly from the national level; and (5) the top 5 research areas were chemistry, engineering, physics, material science, environmental science, and ecology, which accounted for 64.7% of all papers. Finally, the present study puts forward some recommendations for the decision-making process in the strategic layout of S&T innovation in Gansu Province.
    Keywords:  14th Five-Year Plan; Bibliometrics; Gansu Province; Knowledge graph; S&T innovation; Strong science and technology
    DOI:  https://doi.org/10.1007/s10668-023-03124-0
  78. J Acad Ophthalmol (2017). 2021 Jul;13(2): e210-e215
      Purpose  The aim of the study is to investigate sex differences in academic rank, publication productivity, and National Institute of Health (NIH) funding among oculoplastic surgeons and whether there is an association between American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) membership and scholarly output. Methods  Sex, residency graduation year, and academic rank were obtained from institutional websites of 113 U.S. ophthalmology programs. H-indices and m-quotients were obtained from the Scopus database. NIH funding information was obtained from the NIH Research Portfolio Online Reporting Tool. Results  Of the 272 surgeons, 74 (30.2%) were females. When adjusted for career duration, differences in female to male proportions were only significant at the rank of assistant professor (assistant: 74.3 vs. 48.5%, p  = 0.047; associate: 18.9 vs. 24.6%, p  = 0.243; full professor: 13.0 vs. 37.2%, p  = 0.114). Women had a shorter career duration than men [10.0 (interquartile range or IQR 12.0) vs. 21.0 (IQR 20.0) years; p  < 0.001] and a lower h-index [4.0 (IQR 5.0) vs. 7.0 (IQR 10.0); p  < 0.001], but similar m-quotients [0.4 (IQR 0.4) vs. 0.4 (IQR 0.4); p  = 0.9890]. Among ASOPRS members, females had a lower h-index than males [5.0 (IQR 6.0) vs. 9.0 (IQR 10.0); p  < 0.001] due to career length differences. No difference in productivity between sexes was found among non-ASOPRS members. ASOPRS members from both sexes had higher scholarly output than their non-ASOPRS counterparts. Just 2.7% (2/74) of females compared with 5.3% (9/171) of males received NIH funding ( p  = 0.681). Conclusion  Sex differences in academic ranks and h-indices are likely due to the smaller proportion of females with long career durations. ASOPRS membership may confer opportunities for increased scholarly output.
    Keywords:  NIH funding; academic rank; disparities; gender; oculoplastic; ophthalmology; publication productivity
    DOI:  https://doi.org/10.1055/s-0041-1740312
  79. J Integr Med. 2023 Jun 15. pii: S2095-4964(23)00048-1. [Epub ahead of print]
       OBJECTIVE: This study investigated trends in the study of phytochemical treatment of post-traumatic stress disorder (PTSD).
    METHODS: The Web of Science database (2007-2022) was searched using the search terms "phytochemicals" and "PTSD," and relevant literature was compiled. Network clustering co-occurrence analysis and qualitative narrative review were conducted.
    RESULTS: Three hundred and one articles were included in the analysis of published research, which has surged since 2015 with nearly half of all relevant articles coming from North America. The category is dominated by neuroscience and neurology, with two journals, Addictive Behaviors and Drug and Alcohol Dependence, publishing the greatest number of papers on these topics. Most studies focused on psychedelic intervention for PTSD. Three timelines show an "ebb and flow" phenomenon between "substance use/marijuana abuse" and "psychedelic medicine/medicinal cannabis." Other phytochemicals account for a small proportion of the research and focus on topics like neurosteroid turnover, serotonin levels, and brain-derived neurotrophic factor expression.
    CONCLUSION: Research on phytochemicals and PTSD is unevenly distributed across countries/regions, disciplines, and journals. Since 2015, the research paradigm shifted to constitute the mainstream of psychedelic research thus far, leading to the exploration of botanical active ingredients and molecular mechanisms. Other studies focus on anti-oxidative stress and anti-inflammation. Please cite this article as: Gao B, Qu YC, Cai MY, Zhang YY, Lu HT, Li HX, Tang YX, Shen H. Phytochemical interventions for post-traumatic stress disorder: A cluster co-occurrence network analysis using CiteSpace. J Integr Med. 2023; Epub ahead of print.
    Keywords:  Clustering co-occurrence network; Phytochemical; Post-traumatic stress disorder; Psychedelic; Text analysis
    DOI:  https://doi.org/10.1016/j.joim.2023.06.006
  80. Children (Basel). 2023 Jun 10. pii: 1042. [Epub ahead of print]10(6):
      Infant cry is an adaptive signal of distress that elicits timely and mostly appropriate caring behaviors. Caregivers are typically able to decode the meaning of the cry and respond appropriately, but maladaptive caregiver responses are common and, in the worst cases, can lead to harmful events. To tackle the importance of studying cry patterns and caregivers' responses, this review aims to identify key documents and thematic trends in the literature as well as existing research gaps. To do so, we conducted a scientometric review of 723 documents downloaded from Scopus and performed a document co-citation analysis. The most impactful publication was authored by Barr in 1990, which describes typical developmental patterns of infant cry. Six major research thematic clusters emerged from the analysis of the literature. Clusters were renamed "Neonatal Pain Analyzer" (average year of publication = 2002), "Abusive Head Trauma" (average year of publication = 2007), "Oxytocin" (average year of publication = 2009), "Antecedents of Maternal Sensitivity" (average year of publication = 2010), "Neurobiology of Parental Responses" (average year of publication = 2011), and "Hormonal Changes & Cry Responsiveness" (average year of publication = 2016). Research clusters are discussed on the basis of a qualitative inspection of the manuscripts. Current trends in research focus on the neurobiology of caregiver responses and the identification of factors promoting maternal sensitivity. Recent studies have also developed evidence-based strategies for calming crying babies and preventing caregivers' maladaptive responses. From the clusters, two topics conspicuously call for future research: fathers' responsiveness to infant cry and the impact of caregiver relationship quality on cry responsiveness.
    Keywords:  CiteSpace; caregiver responsiveness; cry responsiveness; infant cry; infant vocalizations; parental sensitivity; scientometrics
    DOI:  https://doi.org/10.3390/children10061042
  81. Ann Glob Health. 2023 ;89(1): 42
       Background: Decolonization in global health is a recent movement aimed at relinquishing remnants of supremacist mindsets, inequitable structures, and power differentials in global health.
    Objective: To determine the author demographics of publications on decolonizing global health and global health partnerships between low- and middle-income countries (LMICs) and high-income countries (HICs).
    Methods: We conducted a cross-sectional analysis of publications related to decolonizing global health and global health partnerships from the inception of the selected journal databases (i.e., Medline, CAB Global Health, EMBASE, CINAHL, and Web of Science) to November 14, 2022. Author country affiliations were assigned as listed in each publication. Author gender was assigned using author first name and the software genderize.io. Descriptive statistics were used for author country income bracket, gender, and distribution.
    Findings: Among 197 publications on decolonizing global health and global health partnerships, there were 691 total authors (median 2 authors per publication, interquartile range 1, 4). Publications with author bylines comprised exclusively of authors affiliated with HICs were most common (70.0%, n = 138) followed by those with authors affiliated both with HICs and LMICs (22.3%, n = 44). Only 7.6% (n = 15) of publications had author bylines comprised exclusively of authors affiliated with LMICs. Over half (54.0%, n = 373) of the included authors had names that were female and female authors affiliated with HICs most commonly occupied first author positions (51.8%, n = 102).
    Conclusions: Authors in publications on decolonizing global health and global health partnerships have largely been comprised of individuals affiliated with HICs. There was a marked paucity of publications with authors affiliated with LMICs, whose voices provide context and crucial insight into the needs of the decolonizing global health movement.
    Keywords:  authorship; decolonization; global health partnerships
    DOI:  https://doi.org/10.5334/aogh.4146
  82. Scientometrics. 2023 May 31. 1-31
      COVID-19 has been an unprecedented challenge that disruptively reshaped societies and brought a massive amount of novel knowledge to the scientific community. However, as this knowledge flood continues surging, researchers have been disadvantaged by not having access to a platform that can quickly synthesize emerging information and link the new knowledge to the latent knowledge foundation. Aiming to fill this gap, we propose a research framework and develop a dashboard that can assist scientists in identifying, retrieving, and understanding COVID-19 knowledge from the ocean of scholarly articles. Incorporating principal component decomposition (PCD), a knowledge mode-based search approach, and hierarchical topic tree (HTT) analysis, the proposed framework profiles the COVID-19 research landscape, retrieves topic-specific latent knowledge foundation, and visualizes knowledge structures. The regularly updated dashboard presents our research results. Addressing 127,971 COVID-19 research papers from PubMed, the PCD topic analysis identifies 35 research hotspots, along with their inner correlations and fluctuating trends. The HTT result segments the global knowledge landscape of COVID-19 into clinical and public health branches and reveals the deeper exploration of those studies. To supplement this analysis, we additionally built a knowledge model from research papers on the topic of vaccination and fetched 92,286 pre-Covid publications as the latent knowledge foundation for reference. The HTT analysis results on the retrieved papers show multiple relevant biomedical disciplines and four future research topics: monoclonal antibody treatments, vaccinations in diabetic patients, vaccine immunity effectiveness and durability, and vaccination-related allergic sensitization.
    Keywords:  COVID-19; Intelligent bibliometrics; Knowledge retrieval; Topic analysis
    DOI:  https://doi.org/10.1007/s11192-023-04747-w
  83. Int J Environ Sci Technol (Tehran). 2023 Apr 10. 1-28
      Microplastic distribution and pollution as emerging contaminants have become a leading environmental issue globally, owing to their ecological and health implications on biota and humans. Although several bibliometric studies have been reported on microplastics, they are mostly restricted to selected environmental media. As a result, the present study aimed at assessing the literature growth trend of microplastics-related research and their distribution in the environment using a bibliometric approach. The Web of Science Core Collection was explored to retrieve published articles on microplastics from 2006 to 2021, and the data were analysed using the Biblioshiny package of RStudio. This study also highlighted filtration, separation, coagulation, membrane technology, flotation, bionanomaterials, bubble barrier devices, and sedimentation as MP remediation techniques. In the present study, a total of 1118 documents were collected from the literature search; the documents/author and authors/document were 0.308 and 3.25, respectively. A significant growth rate of 65.36% was recorded with notable progress between 2018 and 2021. China, the USA, Germany, the UK, and Italy recorded the highest number of publications within the period under consideration. A collaboration index of 3.32 was also relatively high, with the Netherlands, Malaysia, Iran, France, and Mexico having the highest MCP ratios, respectively. It is anticipated that findings from this study will help the policymakers in addressing issues concerning microplastic pollution assist the researchers in identifying areas to concentrate their studies, and where to seek collaboration in their future research plans.
    Supplementary Information: The online version contains supplementary material available at 10.1007/s13762-023-04916-7.
    Keywords:  Accumulation; Environmental matrices; Health risks; Marine environment; Microplastics; Priority organic pollutants
    DOI:  https://doi.org/10.1007/s13762-023-04916-7
  84. Brain Spine. 2023 ;3 101720
      •The top three countries made up 56.7% of the total open-access (OA) contributions.•Low and lower-middle-income countries are less than 8% of the total OA publications.•There is a disparity in academic voice in the neurosurgical literature.•Disparities potentially affect neurosurgery practice and knowledge dissemination.
    Keywords:  Global neurosurgery; Neurosurgery literature; Open-access; Publication disparity
    DOI:  https://doi.org/10.1016/j.bas.2023.101720
  85. J Assist Reprod Genet. 2023 Jun 29.
       PURPOSE: Research about ethical, legal, and social implications (ELSI) of assisted reproductive technologies (ART) is influenced by cultural and value-based perspectives. It impacts regulations, funding, and clinical practice, and shapes the perception of ART in society. We analyze trends in the global literature on ELSI of ART between 1999 and 2019. As most output is produced by North America, Western Europe, and Australia, we focus on international research, i.e., academic articles studying a different country than that of the corresponding author.
    METHODS: The corpus, extracted from PubMed, Web of Science, and Scopus, includes 7714 articles, of which 1260 involved international research. Analysis is based on titles, abstracts and keywords, classification into ART fields and Topic Modeling, the countries of corresponding author, and countries mentioned in abstracts.
    RESULTS: An absolute increase in the number of international studies, and their relative proportion. Trends of decentralization are apparent, yet geographic centralization remains, which reflects an unequal distribution of research funds across countries and may result in findings that do not reflect global diversity of norms and values. Preference for studying conceptual challenges through philosophical analysis, and for fields that concern only a portion of ART cycles. Less attention was dedicated to economic analysis and barriers to access, or to knowledge of and attitudes. International studies provide an opportunity to expand and diversify the scope of ELSI research.
    CONCLUSION: We call on the research community to promote international collaborations, focus on less explored regions, and divert more attention to questions of cost, access, knowledge, and attitudes.
    Keywords:  Assisted reproductive technologies; Ethical, social, and legal implications; Geographic distribution of research; International research; Mapping; Topic modeling
    DOI:  https://doi.org/10.1007/s10815-023-02834-8
  86. Educ Inf Technol (Dordr). 2023 Mar 01. 1-11
       OBJECTIVE: To analyze the research hotspots and trends of nursing scenario simulation teaching at home and abroad, and to provide reference for future nursing talent education.
    METHODS: CNKI and Web of Science databases were searched. From the establishment of the database to April 2022, relevant literature on nursing scenario simulation teaching research at home and abroad was retrieved, and Cite Space software was used for visual analysis.
    RESULTS: The research focus on China was the application and application effect of nursing scenario simulation teaching. The research hotspots abroad are the quality evaluation, reliability and influence of nursing scenario simulation teaching.
    CONCLUSION: The research and development of nursing scenario simulation teaching gradually tend to be systematic.
    Keywords:  Hot spots; Nursing; Situational simulation teaching; Visualization analysis
    DOI:  https://doi.org/10.1007/s10639-023-11667-y
  87. J Acad Ophthalmol (2017). 2022 Jan;14(1): e7-e17
      Objective  The aim of the study is to investigate the characteristics of first-year residents associated with attending a top-ranked United States (U.S.) ophthalmology residency program over the past decade. Methods  First-year ophthalmology residents in 2009, 2013, 2016, and 2019 were identified from institutional websites, Doximity, LinkedIn and the Wayback Machine. Publications were obtained from Scopus and Google Scholar; research productivity was measured using the h -index, and medical school region based on U.S. Census Bureau designations. Medical school and ophthalmology training program rankings were based on U.S. News & World Report (U.S. News) rankings and National Institutes of Health (NIH) funding. One-way ANOVA, Wilcoxon rank sum, χ 2 , and t -tests were used to analyze trends, and odds ratios (ORs) were calculated using logistic regression. Results  Data were obtained on 81% (1,496/1,850) of the residents; 43% were female; 5% were international medical graduates (IMGs); and 10% had other graduate degrees. Over the decade, the mean h -index increased (0.87-1.26; p <0.05) and the proportion of residents who attended a top 20 medical school decreased (28-18%; p <0.05). In a multivariate logistic regression model, characteristics associated with being a first-year resident in a top 20 program ranked by U.S. News were female gender [OR: 1.32, 95% CI: 1.02-1.72], having a Master's degree [OR: 2.28, 95% CI: 1.29-4.01] or PhD [OR: 2.23, 95% CI: 1.32-3.79], attending a top 20 [OR: 5.26, 95% CI: 3.66-7.55] or a top 40 medical school by NIH funding [OR: 2.45, 95% CI: 1.70-3.54], attending a medical school with a mean USMLE Step 2 score above 243 [OR: 1.64, 95% CI: 1.01-2.67] or located in the Northeast [OR: 2.00, 95% CI: 1.38-2.89] and having an h -index of one or more [OR: 1.92, 95% CI: 1.47-2.51]. Except for gender, these characteristics were also significantly associated with matching to a top 20 ophthalmology program by NIH funding. Conclusion  Female gender, graduate degrees, research productivity, and attending a medical school with high research productivity, high mean USMLE Step 2 score or in the Northeast were key characteristics of first-year residents in top-ranked U.S. ophthalmology residency programs.
    Keywords:  ophthalmology; research productivity; residency; residency match
    DOI:  https://doi.org/10.1055/s-0041-1735152
  88. Sage Open. 2023 Apr-Jun;13(2):13(2): 21582440231182060
      To analyze the directions for future research suggested and to project future research plans, we extract relevant text from these publications with respect to COVID-19-related research based on 54,136 relevant academic journals published from the initial outbreak of COVID-19 in January 2020 until December 2020. First, we extract and preprocess the corpus and then determine that, according to the Elbow method, the optimal number of clusters is 7. Then, we construct a text clustering model based on an autoencoder, with the support of an artificial neural network. Distance measurements, such as correlation, cosine, Braycurtis, and Jaccard are compared, and the clustering results are evaluated with normal mutual information. The results show that cosine similarity has the best effect on clustering of COVID-19-related documents. A topic model analysis shows that the directions of future research can mainly be grouped into the following seven categories: infectivity testing, genome analysis, vaccine testing, diagnosis and infection characteristics, pandemic management, nursing care, and clinical testing. Among them, the topics of pandemic management, diagnosis and infection characteristics, and clinical testing trended upward in proportion to future directions. The topic of vaccine testing remains steady over the observation window, whereas other topics (infectivity testing, genome analysis, and nursing care) slowly trended downward. Among all the topics, medical research comprises 80%, and about 20% of the topics are related to public management, government functions, and economic development. This study enriches our scientific understanding of COVID-19 and helps us to effectively predict future scientific research output on COVID-19.
    Keywords:  COVID-19; autoencoder; deep learning; text mining; topic model
    DOI:  https://doi.org/10.1177/21582440231182060
  89. Front Neurosci. 2023 ;17 1136500
      Hypoxic-ischemic encephalopathy (HIE) is the leading cause of long-term neurological disability in neonates and adults. Through bibliometric analysis, we analyzed the current research on HIE in various countries, institutions, and authors. At the same time, we extensively summarized the animal HIE models and modeling methods. There are various opinions on the neuroprotective treatment of HIE, and the main therapy in clinical is therapeutic hypothermia, although its efficacy remains to be investigated. Therefore, in this study, we discussed the progress of neural circuits, injured brain tissue, and neural circuits-related technologies, providing new ideas for the treatment and prognosis management of HIE with the combination of neuroendocrine and neuroprotection.
    Keywords:  bibliometric analysis; hypothermia; hypoxic-ischemic encephalopathy (HIE); monkey; neural circuits
    DOI:  https://doi.org/10.3389/fnins.2023.1136500
  90. Toxics. 2023 Jun 17. pii: 539. [Epub ahead of print]11(6):
      The study of microplastics and their impact on aquatic ecosystems has received increasing attention in recent years. Drawing from an analysis of 814 papers related to microplastics published between 2013 and 2022 in the Web of Science Core Repository, this paper explores trends, focal points, and national collaborations in freshwater microplastics research, providing valuable insights for future studies. The findings reveal three distinct stages of microplastics: nascent development (2013-2015), slow rise (2016-2018), and rapid development (2019-2022). Over time, the focus of research has shifted from "surface", "effect", "microplastic pollution", and "tributary" to "toxicity", "species", "organism", "threat", "risk", and "ingestion". While international cooperation has become more prevalent, the extent of collaboration remains limited, mostly concentrated among English-speaking countries or English and Spanish/Portuguese-speaking countries. Future research directions should encompass the bi-directional relationship between microplastics and watershed ecosystems, incorporating chemical and toxicological approaches. Long-term monitoring efforts are crucial to assessing the sustained impacts of microplastics.
    Keywords:  ecological impact; freshwater environment; microplastics; pollution; research progress
    DOI:  https://doi.org/10.3390/toxics11060539
  91. Cancer Causes Control. 2023 Jun 24.
       PURPOSE: The Cancer Prevention and Control Research Network (CPCRN) is a national network focused on accelerating the translation of cancer prevention and control research evidence into practice through collaborative, multicenter projects in partnership with diverse communities. From 2003 to 2022, the CPCRN included 613 members.
    METHODS: We: (1) characterize the extent and nature of collaborations through a bibliometric analysis of 20 years of Network publications; and (2) describe key features and functions of the CPCRN as related to organizational structure, productivity, impact, and focus on health equity, partnership development, and capacity building through analysis of 22 in-depth interviews and review of Network documentation.
    RESULTS: Searching Scopus for multicenter publications among the CPCRN members from their time of Network engagement yielded 1,074 collaborative publications involving two or more members. Both the overall number and content breadth of multicenter publications increased over time as the Network matured. Since 2004, members submitted 123 multicenter grant applications, of which 72 were funded (59%), totaling more than $77 million secured. Thematic analysis of interviews revealed that the CPCRN's success-in terms of publication and grant productivity, as well as the breadth and depth of partnerships, subject matter expertise, and content area foci-is attributable to: (1) its people-the inclusion of members representing diverse content-area interests, multidisciplinary perspectives, and geographic contexts; (2) dedicated centralized structures and processes to enable and evaluate collaboration; and (3) focused attention to strategically adapting to change.
    CONCLUSION: CPCRN's history highlights organizational, strategic, and practical lessons learned over two decades to optimize Network collaboration for enhanced collective impact in cancer prevention and control. These insights may be useful to others seeking to leverage collaborative networks to address public health problems.
    Keywords:  Cancer prevention and control; Collaboration; Community engagement; Implementation science; Mixed methods; Research translation
    DOI:  https://doi.org/10.1007/s10552-023-01691-1
  92. J Acad Ophthalmol (2017). 2021 Jul;13(2): e114-e118
      Objective  The aim of the study is to identify differences for cataract surgery, total procedural volume, and publication rates between residents by gender, underrepresented minority (URM) status, and welcoming a child during ophthalmology residency. Design  This is a retrospective, cross-sectional study. Participants  A total of 89 residents graduating from 2002 to 2020 at a single program were included. Methods  A multiple linear regression model was created to determine factors predictive of the number of cataract surgeries performed as the primary surgeon, total procedural volume, number of publications, or first author publications. Independent variables included resident gender, URM status, PhD degree, welcoming a child during residency, and graduation year. Results  Of the 89 graduating residents included in this study, identifying as female (45 women, 50.6%) and as URM (eight identifying as URM, 9.0%) was not associated with a difference in surgical or research volume. Female residents performed a mean (SD) of 240.1 (55.1) cataract surgeries while male residents performed 210.6 (46.1) cataract surgeries. Residents identifying as URM completed 228.1 (41.9), while non-URM residents completed 234.8 (51.9) cataract surgeries. Since 2008, eight female residents (22.2%) and two male residents (6.9%) added children to their families. Welcoming a child to the family was also not associated with decreased surgical or publication volume. Number of cataract surgeries, total procedures, and number of publications did increase over time ( p <0.001), as each graduation year was associated with 5.4 (95% CI: 3.9, 7.1) more cataract surgeries and 30.5 (95% CI: 25.7, 36.9) more procedures. Each year was also associated with 0.24 (95% CI: 0.09, 0.38) more publications and 0.18 (95% CI: 0.08, 0.28) more first author publications. Conclusion  Surgical and research productivity has increased, and female residents and residents who identify as URM did not have fewer cataract surgeries or procedures. Welcoming a child also did not correlate with differences in surgical or procedural volume. Programs should continue to promote equitable surgery and procedural distributions as well as identify more targeted strategies to encourage and recruit underrepresented medical students into ophthalmology.
    Keywords:  cataract surgery; gender; ophthalmology; publication rate; surgical volume; underrepresented minority
    DOI:  https://doi.org/10.1055/s-0041-1735580
  93. Circ Econ Sustain. 2023 Mar 25. 1-25
      Plastic makes our society more practical and safer. It is hard to consider eliminating plastic in some sectors, such as the medical field. However, after use, plastic waste becomes a global problem without precedents, and when not properly disposed of, it can cause several socio-environmental problems. Some possible solutions are recycling, the circular economy, proper waste management, and consumer awareness. Consumers play a crucial role in preventing problems caused by plastic. In this work, consumer awareness of plastic is discussed according to the point of view of the research areas-environmental science, engineering, and materials science-based on the analysis of the main authors' keywords obtained in a literature search in the Scopus database. Bibliometrix analyzed the Scopus search results. The results showed that each area presents different concerns and priorities. The current scenario, including the main hotspots, trends, emerging topics, and deficiencies, was obtained. On the contrary, the concerns from the literature and those of the daily lives of consumers do not seem to fit in, which creates a gap. By reducing this gap, the distance between consumers awareness and their behavior will be smaller.
    Keywords:  Authors’ keywords; Awareness; Bibliometric analysis; Consumer; Plastic; Polymer
    DOI:  https://doi.org/10.1007/s43615-023-00263-4
  94. J Assist Reprod Genet. 2023 Jun 29.
       PURPOSE: A significant portion of the research on assisted reproductive technologies explores ethical, legal, and social implications. It has an impact on social perceptions, the evolution of norms of clinical practices, regulations and public funding. This paper reviews and maps the geographical distribution to test the hypothesis of geographical concentration and classifies the output by fields and topics.
    METHODS: We queried PubMed, Scopus and the Web of Science for documents published between 1999 and 2019, excluding clinical trials and medical case reports. Documents were analyzed according to their titles, abstracts and keywords and were classified to assisted reproductive fields and by Topic Modeling. We analyzed geographic distribution.
    RESULTS: Research output increased nearly tenfold. We show a trend towards decentralization of research, although at a slower rate compared with clinical assisted reproduction research. While the U.S. and the U.K.'s share has dropped, North America and Western Europe are still responsible for more than 70%, while China and Japan had limited participation in the global discussion. Fertility preservation and surrogacy have emerged as the most researched categories, while research about genetics was less prominent.
    CONCLUSIONS: We call to enrich researchers' perspectives by addressing local issues in ways that are tailored to local cultural values, social and economic contexts, and differently structured healthcare systems. Researchers from wealthy centers should conduct international research, focusing on less explored regions and topics. More research on financial issues and access is required, especially regarding regions with limited public funding.
    Keywords:  Assisted reproductive technologies; Ethical social and legal implications; Geographic distribution of research; Mapping; Topic modeling
    DOI:  https://doi.org/10.1007/s10815-023-02854-4
  95. JAMA Netw Open. 2023 06 01. 6(6): e2318877
       Importance: Many meta-analyses have been conducted on a wide array of topics, and many of these have focused on treatment efficacy of drugs or bias in interventional studies on a specific topic.
    Objective: To examine the factors associated with having a positive study conclusion in meta-analyses in the field of oncology.
    Evidence Review: All meta-analyses published between January 1, 2018, and December 31, 2021, on 5 oncology journal websites were identified and study characteristics, study results, and information on study authors were abstracted. The meta-analysis authors' conclusions were coded as positive, negative, or equivocal, and each article subject matter was coded as one that could affect profits and marketing of a company. Whether an association existed between study characteristics and authors' conclusions was also examined.
    Findings: Database searches resulted in 3947 potential articles, of which 93 meta-analyses were included in this study. Of the 21 studies with author funding from industry, 17 studies (81.0%) reported favorable conclusions. Of the 9 studies that received industry funding, 7 (77.8%) reported favorable conclusions, and of the 63 studies that did not have author or study funding from industry, 30 (47.6%) reported favorable conclusions. Studies that were funded through nonindustry sources and authors who had no relevant conflict of interest had the lowest percentage of positive conclusions and the highest percentage of negative and equivocal conclusions compared with studies with other sources of potential conflict of interest.
    Conclusions and Relevance: In this cross-sectional study of meta-analyses published in oncology journals, multiple factors were associated with having a positive study conclusion, which suggests that future research should be performed to elucidate reasons for more favorable conclusions among studies with study or author industry funding.
    DOI:  https://doi.org/10.1001/jamanetworkopen.2023.18877
  96. Gels. 2023 May 30. pii: 451. [Epub ahead of print]9(6):
      Polymeric materials have found increasing use in biomedical applications in the last decades. Among them, hydrogels represent the chosen class of materials to use in this field, in particular as wound dressings. They are generally non-toxic, biocompatible, and biodegradable, and they can absorb large amounts of exudates. Moreover, hydrogels actively contribute to skin repair promoting fibroblast proliferation and keratinocyte migration, allowing oxygen to permeate, and protecting wounds from microbial invasion. As wound dressing, stimuli-responsive systems are particularly advantageous since they can be active only in response to specific environmental stimuli (such as pH, light, ROS concentration, temperature, and glucose level). In this review, we briefly resume the human skin's structure and functions, as well as the wound healing phases; then, we present recent advances in stimuli-responsive hydrogels-based wound dressings. Lastly, we provide a bibliometric analysis of knowledge produced in the field.
    Keywords:  bibliometric analysis; hydrogels; stimuli-responsive; wound dressing; wound healing
    DOI:  https://doi.org/10.3390/gels9060451
  97. Accid Anal Prev. 2023 Jun 26. pii: S0001-4575(23)00202-6. [Epub ahead of print]190 107155
      The application of naturalistic driving data (NDD) has the potential to answer critical research questions in the area of driving behavior assessment, as well as the impact of exogenous and endogenous factors on driver safety. However, the presence of a large number of research domains and analysis foci makes a systematic review of NDD applications challenging in terms of information density and complexity. While previous research has focused on the execution of naturalistic driving studies and on specific analysis techniques, a multifaceted aggregation of NDD applications in Intelligent Transportation System (ITS) research is still unavailable. In spite of the current body of work being regularly updated with new findings, evolutionary nuances in this field remain relatively unknown. To address these deficits, the evolutionary trend of NDD applications was assessed using research performance analysis and science mapping. Subsequently, a systematic review was conducted using the keywords "naturalistic driving data" and "naturalistic driving study data". As a result, a set of 393 papers, Published between January 2002-March 2022, was thematically clustered based on the most common application areas utilizing NDD. the results highlighted the relationship between the most crucial research domains in ITS, where NDD had been incorporated, and application areas, modeling objectives, and analysis techniques involving naturalistic databases.
    Keywords:  Bibliometric analysis; Naturalistic data analytics; Naturalistic driving data; Naturalistic driving study; Systematic review
    DOI:  https://doi.org/10.1016/j.aap.2023.107155
  98. PLoS One. 2023 ;18(6): e0287677
      The title of an article is the main entrance for reading the full article. The aim of our work therefore is to examine differences of title content and form between original research articles and its changes over time. Using PubMed we examined title properties of 500 randomly chosen original research articles published in the general major medical journals BMJ, JAMA, Lancet, NEJM and PLOS Medicine between 2011 and 2020. Articles were manually evaluated with two independent raters. To analyze differences between journals and changes over time, we performed random effect meta-analyses and logistic regression models. Mentioning of results, providing any quantitative or semi-quantitative information, using a declarative title, a dash or a question mark were rarely used in the title in all considered journals. The use of a subtitle, methods-related items, such as mentioning of methods, clinical context or treatment increased over time (all p < 0.05), while the use of phrasal tiles decreased over time (p = 0.044). Not a single NEJM title contained a study name, while the Lancet had the highest usage of it (45%). The use of study names increased over time (per year odds ratio: 1.13 (95% CI: [1.03‒1.24]), p = 0.008). Investigating title content and form was time-consuming because some criteria could only be adequately evaluated by hand. Title content changed over time and differed substantially between the five major medical journals. Authors are advised to carefully study titles of journal articles in their target journal prior to manuscript submission.
    DOI:  https://doi.org/10.1371/journal.pone.0287677
  99. Med Teach. 2023 Jun 27. 1-6
       PURPOSE: To explore and describe the highly cited articles' themes of research in medical education and to provide an insight into and reflection on which the elites of medical education society invested their energies from 2009 to 2018.
    METHODS: An in-depth content analysis as a research technique for the objective, systematic, and quantitative description of the manifest content of communication was used to quantitatively assess subject interests, methods, and other characteristics associated with citation of published studies in medical education research. Meaning units were compacted and coded with labels and categories in two phases.
    RESULTS: Among a variety of topics, methods, and strategies, 764 codes, 24 descriptive themes, and seven categories were extracted from the content analysis as the most prominent. Categories of medical education research were: modern technologies updating in medical education; learner performance improvement; sociological aspects of medical education; clinical reasoning; research methodology concerns of medical education; instructional design educational models; and professional aspects of medical education.
    CONCLUSIONS: Commitment to continuous revision of educational emphasis and concerns on technological, sociological, and methodological concerns were the most repeated components of the highly cited articles that were ascertained through increased structure course designs and instructional strategies of the flipped classrooms to realize clinical reasoning and performance improvement.[Box: see text].
    Keywords:  Medical education research; change; content analysis; highly cited articles; theory
    DOI:  https://doi.org/10.1080/0142159X.2023.2225728
  100. Qual Manag Health Care. 2023 Jun 27.
       BACKGROUND AND OBJECTIVE: Little information is available on how to assess the impact of research studies conducted in government hospitals in Latin America and specifically in Mexico. We aimed to determine the returns on investment of the research projects that were carried out in the Hospital General "Dr. Manuel Gea Gonzalez" (HGMGG), a general university hospital located in Mexico City, using a categorization model.
    METHODS: We conducted a study including bibliometric analyses of publications associated with all research studies performed during the period 2016-2019 in the HGMGG and investigator interviews, according to the payback framework categorization model.
    RESULTS: All studies analyzed had a positive impact based on outcomes in 5 "payback categories": (1) knowledge; (2) research targeting, capacity building, and absorption; (3) policy and product development; (4) health benefits; and (5) broader economic benefits.
    CONCLUSIONS: To date, it has not been possible to establish a set of indicators that show the results of the investigations carried out by medical specialists in training, who carry out the bulk of medical care in general hospitals and in the National Institutes of Health in Mexico. We identified, in the 5 categories of the payback framework model, different areas of opportunity to improve the benefits of the hospital's medical services through the development of scientific research projects.
    DOI:  https://doi.org/10.1097/QMH.0000000000000415
  101. Function (Oxf). 2023 ;4(4): zqad032
      
    Keywords:  impact factors; mental health crisis; research assessment; research funding models; research grants; useful knowledge
    DOI:  https://doi.org/10.1093/function/zqad032
  102. J Grad Med Educ. 2023 Jun;15(3): 365-372
       Background: Scholarly activity is a requirement for most graduate medical education training programs. However, barriers exist for residents to accomplish projects.
    Objective: To evaluate the correlation between a resident research mentoring team (RRMT) program and meeting presentations and publications of resident research projects. We further plan to report feasibility of the RRMT.
    Methods: We performed a before-and-after study of meeting presentations and/or publication of resident research projects before institution of the RRMT (2004-2011) and post-RRMT implementation (2016-2019). The RRMT is a diverse group of faculty, statisticians, and research staff who meet regularly with residents to provide guidance for their research studies. It is part of overall research support from the department, which also includes biostatistics, database and regulatory help, travel funds, and project budget funds. Data on meeting presentations and publications were collected from Google Scholar, PubMed, Scopus, and the IUPUI ScholarWorks institutional repository, using resident and faculty names and titles of projects. Comparisons of pre- and post-RRMT groups were made.
    Results: Seventy-four residents were in the pre-RRMT group and 40 were in the post-RRMT group. Post-RRMT residents published, presented, and combined published or presented their projects more frequently than those in pre-RRMT group (57.5% vs 28.4%, P=.002; 50% vs 16.2%, P=.001; 67.5% vs 37.8%, P=.002). Controlling for winning a Research Day award and pursuing a fellowship, being in the post-RRMT group was independently associated with presentation or publication of the resident research project (OR 3.62, 95% CI 1.57-8.83).
    Conclusions: Support of resident scholarly activity, such as thorough implementation of a program like the RRMT, is associated with increased presentations and publications of research projects.
    DOI:  https://doi.org/10.4300/JGME-D-22-00499.1
  103. Arthrosc Sports Med Rehabil. 2023 Jun;5(3): e703-e706
       Purpose: To determine the proportion of faculty members at the top orthopaedic sports medicine fellowship programs who completed a fellowship at one of these programs themselves, how many remained at their fellowship training programs as an attending (institutional loyalty), where they most commonly completed residency and medical school, and to characterize their research productivity.
    Methods: The fellowship programs of current orthopaedic sports medicine fellowship faculty members at each of the top 10 orthopaedic sports medicine fellowship programs (based on a recent study) were determined by searching program websites or contacting program coordinators. For each program, we determined the proportion of faculty members who completed fellowship at one of these top 10 programs and the proportion who remained at their fellowship program as an attending. Residency and medical school information was found for faculty members on their professional websites. To determine research output, each faculty member's name was searched within the Scopus database and the number of publications was recorded.
    Results: Data were obtained from each of the top 10 sports medicine fellowship programs. Fifty-eight of 82 (70.7%) fellowship faculty members completed fellowship at a top 10 program. Regarding institutional loyalty, 36 of 82 (43.9%) fellowship faculty members remained at the program where they trained, with one program led entirely by alumni. The average number of publications per faculty member was 130.6, with a range among the 10 programs of 23-355.8.
    Conclusions: Most orthopaedic sports medicine fellowship faculty at the top perceived training programs completed a fellowship at one of these same programs and maintain high research productivity.
    Clinical Relevance: Orthopaedic surgery trainees who wish to become faculty members at one of the top orthopaedic sports medicine training programs should aim to match into one of these top programs when applying for fellowship.
    DOI:  https://doi.org/10.1016/j.asmr.2023.03.012
  104. Arch Phys Med Rehabil. 2023 Jun 24. pii: S0003-9993(23)00362-3. [Epub ahead of print]
       OBJECTIVE: To investigate the rate of registered protocols published as research papers as a measure of publication bias, and the concordance rates of the primary outcomes between research protocol and published papers as a measure of selective outcome reporting bias in randomized controlled trials (RCTs) related to rehabilitation.
    DATA SOURCES: Protocols related to RCTs were extracted from electronic databases, the University Hospital Medical Information Network (UMIN), International Standard Research Clinical Trial Number (ISRCTN), ClinicalTrials.gov, and MEDLINE. Published papers were retrieved from MEDLINE.
    STUDY SELECTION: The inclusion criteria were as follows: (1) initial registration (UMIN, ISRCTN, ClinicalTrials.gov) within the designated period; (2) published as a paper from a research protocol in MEDLINE (PubMed); and (3) written in English or Japanese. The search period was from January 1, 2013 to December 31, 2020.
    DATA EXTRACTION: The outcome of this study was set as the rate of published papers that were consistent with the extracted research protocol and the concordance rate between the primary outcomes in published papers and in protocols. The concordance rate of the primary outcomes was evaluated by checking whether the description in the research protocol matched that in the paper's abstract and main text.
    DATA SYNTHESIS: Out of the 5,597 research protocols registered, only 727 were published (13.0%). The concordance rates of the primary outcomes were 48.7% and 72.6% in the abstract and main text, respectively.
    CONCLUSIONS: This study revealed major discrepancies between the number of research protocols and published papers, and difference of description regarding the primary outcomes in published papers which were already defined in the research protocols.
    TRIAL REGISTRATION: Not applicable.
    Keywords:  Decision making; Evidence-based medicine; Publication bias; Reporting bias
    DOI:  https://doi.org/10.1016/j.apmr.2023.06.006
  105. Sci Data. 2023 Jun 27. 10(1): 419
      Commonly used data citation practices rely on unverifiable retrieval methods which are susceptible to content drift, which occurs when the data associated with an identifier have been allowed to change. Based on our earlier work on reliable dataset identifiers, we propose signed citations, i.e., customary data citations extended to also include a standards-based, verifiable, unique, and fixed-length digital content signature. We show that content signatures enable independent verification of the cited content and can improve the persistence of the citation. Because content signatures are location- and storage-medium-agnostic, cited data can be copied to new locations to ensure their persistence across current and future storage media and data networks. As a result, content signatures can be leveraged to help scalably store, locate, access, and independently verify content across new and existing data infrastructures. Content signatures can also be embedded inside content to create robust, distributed knowledge graphs that can be cited using a single signed citation. We describe applications of signed citations to solve real-world data collection, identification, and citation challenges.
    DOI:  https://doi.org/10.1038/s41597-023-02230-y