bims-evares Biomed News
on Evaluation of research
Issue of 2023–05–21
ninety-one papers selected by
Thomas Krichel, Open Library Society



  1. Curr Probl Cardiol. 2023 May 10. pii: S0146-2806(23)00207-4. [Epub ahead of print] 101790
      
    Keywords:  Bibliometric Analysis; Co-Words Analysis; Scopus; Ventricular Remodeling
    DOI:  https://doi.org/10.1016/j.cpcardiol.2023.101790
  2. Healthcare (Basel). 2023 Apr 28. pii: 1267. [Epub ahead of print]11(9):
      The number of research related to traumatic experiences in people with autism spectrum disorder (ASD) has grown exponentially, yet there are no bibliometric studies in this field. This article aimed to analyze the literature related to trauma and ASD published in Web of Science (WoS). Papers on trauma and ASD were retrieved from the WoS. Analysis and visualization of selected documents were performed using MS Excel (v16.0), VOS viewer (version 1.6.15), and R package (Biblioshiny, version 2.0). A total of 147 articles were included in this study. The results showed that production has been increasing over the last few years. Among the countries identified, the USA published the largest number of articles. Arvid Nikolai Kildahl, Sissel Berge Helverschou, and Liliana Dell'Osso were the authors with the most number of publications on this topic, and Autism was the most productive journal. The main research topics associated with ASD were post-traumatic stress and traumatic experiences in childhood. This bibliometric study contributes to understanding research trends on trauma and ASD by evaluating relevant publications in the last decades. The results of this bibliometric analysis can serve as a basis and orientation for new studies.
    Keywords:  autism; bibliometrics; post-traumatic stress disorder; trauma
    DOI:  https://doi.org/10.3390/healthcare11091267
  3. J Pain Res. 2023 ;16 1499-1515
       Background: Increasing evidence indicates that opioids markedly affect the immune system. However, there are few studies on opioids and immunomodulation using bibliometric analysis.
    Purpose: We aimed to provide a comprehensive overview of the research status and trends of the influence of opioids on immunomodulation using a bibliometric approach.
    Methods: Articles related to opioids and immunomodulation published from 2000 to 2022 were obtained from the Science Citation Index Expanded of the Web of Science Core Collection by searching keywords related to opioids and immunomodulation. Bibliometric analyses and visualizations were conducted using the CiteSpace and VOSviewer software programs.
    Results: From 2000 to 2022, a total of 3242 research articles on opioids and immunomodulation were published in 1126 academic journals by 16,555 authors in 3368 institutions from 102 countries/regions. A majority of publications were from the US and China, and the University of Minnesota System and Chinese Academy of Sciences were the most active institutions. Tsong-long Hwang had published the most papers, while Sabita Roy had the most cocitations. The Journal of Ethnopharmacology published the most papers on opioids and immunomodulation, the Journal of Immunology was the top cocited journal, and the major area of these publications were molecular, biological, and genetic. The top three keywords were "expression", "activation", and "inflammation."
    Conclusion: The number of studies on opioids and immunomodulation has increased sharply all over the world in the last two decades. This is the first bibliometric study to comprehensively summarize the collaboration network in this field. It will help scholars to understand not only the basic knowledge structure but also potential collaborations, research trend topics, and hot directions.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; immunomodulation; opioids
    DOI:  https://doi.org/10.2147/JPR.S401326
  4. Quant Imaging Med Surg. 2023 May 01. 13(5): 2953-2974
       Background: Quantitative magnetic resonance imaging (MRI) has the function of noninvasive quantitative evaluation, providing unique advantages in intervertebral disc degeneration (IDD) assessment. Although studies exploring the field for domestic and international scholars are increasingly being published, there is a lack of systematic scientific measurement and clinical analysis of the literature in this field.
    Methods: Articles published from the respective database establishment to September 30, 2022, were obtained from the Web of Science core collection (WOSCC), PubMed database, and ClinicalTrials.gov. The scientometric software (VOSviewer 1.6.18, CiteSpace 6.1.R3, Scimago Graphica, and R software) were used for bibliometric and knowledge graph visualization analysis.
    Results: We included 651 articles from the WOSCC database and 3 clinical studies from ClinicalTrials.gov for literature analysis. With the passage of time, the number of articles in this field gradually increased. The United States and China were the top 2 countries in terms of the number of publications and citations, and Chinese publications lacked international cooperation and exchange. The author with the most publications was Schleich C, while the author with the most citations was Borthakur A, who have both made important contributions to research in this field. The journal publishing the most relevant articles was Spine, and the journal with the most mean times cited per study was Radiology, both of which are the authoritative journals in this field. Keyword co-occurrence, clustering, timeline view, and emergent analysis revealed that recent studies in this field have focused on quantifying the biochemical components of the degenerated intervertebral disc (IVD). There were few available clinical studies. The more recent clinical studies mainly used molecular imaging technology to explore the relationship between different quantitative MRI sequence values and the IVD biomechanical environment and biochemical components content.
    Conclusions: The study provided a knowledge map of quantitative MRI for IDD research in terms of countries, authors, journals, cited literature, and keywords through bibliometric analysis, and systematically sorted the current status, hotspots, and clinical research features in the field to provide a reference for future research.
    Keywords:  Intervertebral disc degeneration (IDD); bibliometrics; quantitative magnetic resonance imaging; visual analysis
    DOI:  https://doi.org/10.21037/qims-22-1219
  5. Med J Islam Repub Iran. 2023 ;37 31
       Background: Implementing bibliometric indicators is the most prominent way to quantify the current status of research performance. This study aimed to map out the research performance of Iranian medical academics and universities in 2020 and determine its progress from 2016.
    Methods: Data were extracted from the Iranian scientometric information database and universities' scientometric information database. Then, the data were analyzed to provide descriptive statistics of bibliometric indicators. Besides, the association between the research productivity of academics or universities with their background characteristics was investigated using Mann-Whitney U, Kruskal-Wallis, and chi-square tests.
    Results: Iranian medical academics had extensive research productivity from 2016 to 2020, leading to 2.5-fold increase in their median number of papers. The research productivity was heterogeneous among the academics, with an H-index ranging from 0 to 98, and a median of 4. The research productivity was different by gender, academic position, general field of study, and academic degree. The class 1 universities had a higher quantity in research performance; however, there was no difference in quality-related indices comprising citations per paper ratio and high impact publication rate (SJR Q1) among different university classes. The median international collaboration rate has followed a growing trend in recent years and was 17% in 2020.
    Conclusion: There is a remarkable growth in the research productivity of Iranian academics and universities. Iranian research community historically had rare international research collaborations; however, promising growth is shown in this regard. To maintain the growth in research productivity, the country should increase research and development expenditure, address gender disparities, supply universities that are lagging behind, facilitate further international collaboration, and support national journals to be indexed in the international citation databases.
    Keywords:  Bibliometrics; Iranian Universities; Medical Research; Research Activity; Research and Development; Scientometrics
    DOI:  https://doi.org/10.47176/mjiri.37.31
  6. Front Neurol. 2023 ;14 1185900
       Background: The neurotoxicity effects of anesthetic exposure on the developing brain have been one of the current research hotspots and numerous articles were published in the past decades. However, the quality and comparative information of these articles have not been reported. This research aimed to provide a comprehensive overview of the current state of the field by investigating research hotspots and publication trends concerning the neurotoxicity of anesthesia in the developing brain.
    Materials and methods: On 15 June 2022, we searched articles on the neurotoxicity of anesthesia in the developing brain through the Science Citation Index databases from 2002 to 2021. Data of the author, title, publication, funding agency, date of publication, abstract, type of literature, country, journal, keywords, number of citations, and research direction were collected for further analysis.
    Results: We searched and analyzed 414 articles in English on the field of neurotoxicity of anesthesia in the developing brain from 2002 to 2021. The country with the largest number of publications was The United States (US) (n = 226), which also had the largest total number of citations (10,419). Research in this field reached a small peak in 2017. Furthermore, the largest number of articles were published in three journals, Anesthesiology, Anesthesia and Analgesia, and Pediatric Anesthesia. The top 20 articles that were cited most often were studied. In addition, the top hotspots of this area in clinical investigations and basic research were analyzed separately.
    Conclusion: This study provided an overview of the development in the neurotoxicity of anesthesia in the developing brain using bibliometric analysis. Current clinical studies in this area were mainly retrospective; in the future, we should place more emphasis on prospective, multicenter, long-term monitoring clinical studies. More basic research was also needed on the mechanisms of neurotoxicity of anesthesia in the developing brain.
    Keywords:  anesthesia; bibliometric analysis; developing brain; hotspots; neurotoxicity
    DOI:  https://doi.org/10.3389/fneur.2023.1185900
  7. Front Oncol. 2023 ;13 1183405
       Background: In the past 5 years, ferroptosis-associated cancer immunity has been attracted significant research interest.
    Objective: This study was performed to identify and analyze the global output trend for ferroptosis in cancer immunity.
    Methods: Relevant studies were retrieved from the Web of Science Core Collection on Feb 10th, 2023. The VOSviewer and Histcite softwares were utilized to perform the visual bibliometric and deep mining analyses.
    Results: A total of 694 studies (530 articles (76.4%) and 164 (23.6%) review articles) were retrieved from the Web of Science Core Collection for visualization analyses. The top 3 key keywords were ferroptosis, prognosis and immunotherapy. The top 30 local citation score (LCS) authors were all collaborators of Zou Weiping. Deep mining of 51 nanoparticle-related articles showed that BIOMATERIALS was the most popular journal. The primary goal of gene signatures related to ferroptosis and cancer immunity was to establish prognostic predictions.
    Conclusion: There has been a significant increase in ferroptosis-associated immune publications in the recent 3 years. The key research hotspots include mechanisms, prediction and therapeutic outcomes. The most influential article was from the Zou Weiping's group, which proposed that system xc-mediated ferroptosis is induced by CD8(+) T cell-secreted IFNγ after PD-L1 blockage for immunotherapy. The frontier of research in the field of ferroptosis-associated immune is the study on nanoparticle and gene signature The limitation of this bibliometric study is that publications on this topic are few.
    Keywords:  anti-tumor immunity; bibliometric analysis; ferroptosis; gene signature; immunotherapy; nanoparticles
    DOI:  https://doi.org/10.3389/fonc.2023.1183405
  8. Int Wound J. 2023 May 14.
      Extracellular vesicles in wound healing have become an active research field with substantial value and potential. Nevertheless, there are few bibliometric studies in this field. We aimed to visualise the research hot spots and trends of extracellular vesicles in wound healing using a bibliometric analysis to help understand the future development of basic and clinical research. The articles and reviews regarding extracellular vesicles in the wound healing were selected from the Web of Science Core Collection. VOSviewers, CiteSpace and R package "bibliometric" were used to conduct this bibliometric analysis. A total of 1225 articles from 56 countries led by China and the United States were included. The number of publications related to extracellular vesicles increased year by year. Shanghai Jiaotong University, Huazhong University of Science and Technology, Sun Yat-sen University and Central South University are the main research institutions. International Journal of Molecular Sciences is the most popular journal in this field, while Stem Cell Research & Therapy is the most frequently cited journal. These papers come from 7546 authors, among which Zhang Wei has published the most papers and Zhang Bin has the most cocited papers. The research on the treatment strategy of extracellular vesicles in the process of wound healing is the main topic in this field. "exosomes", "miRNA", "angiogenesis", "regenerative medicine", "inflammation" and "diabetic wound" are the main key words of emerging research hotspots. This is the first bibliometric study, which comprehensively summarises the research trend and development of extracellular vesicles and exocrine bodies in wound healing. These informations determine the latest research frontiers and hot directions, and provide reference for the study of extracellular vesicles and exosomes.
    Keywords:  CiteSpace; VOSviewers; bibliometrics; extracellular vesicles; wound healing
    DOI:  https://doi.org/10.1111/iwj.14202
  9. Entropy (Basel). 2023 Apr 07. pii: 632. [Epub ahead of print]25(4):
      Granger causality provides a framework that uses predictability to identify causation between time series variables. This is important to policymakers for effective policy management and recommendations. Granger causality is recognized as the primary advance on the causation problem. The objective of this paper is to conduct a bibliometric analysis of Granger causality publications indexed in the Web of Science database. Harzing's Publish or Perish and VOSviewer were used for performance analysis and science mapping. The first paper indexed was published in 1981 and there has been an upward trend in the annual publication of Granger causality studies which are shifting towards the areas of environmental science, energy, and economics. Most of the publications are articles and proceeding papers under the areas of business economics, environmental science ecology, and neurosciences/neurology. China has the highest number of publications while the United States has the highest number of citations. England has the highest citation impact. This paper also constructed country co-authorship, co-analysis of cited references, cited sources, and cited authors, keyword co-occurrence, and keyword overlay visualization maps.
    Keywords:  Granger causality; VOSviewer; bibliometric analysis; business economics; subject area
    DOI:  https://doi.org/10.3390/e25040632
  10. Int J Med Robot. 2023 May 15. e2527
       BACKGROUND: Robotic transplant surgery has garnered worldwide attention since 2002. Discussions on this issue have led to more publications over the past decade. This study assessed global robotic organ transplantation studies using bibliometric analysis.
    METHOD: The study sample was robotic technique use in organ transplantation publications from 2002 to 2021 in the Web of Science database. We analysed top-cited authors, countries, institutions, journals, and keywords. Citations were used to visualise and analyse target literature in VOSviewer.
    RESULTS: 160 articles were included in the bibliometric study. Among the nations that are presently involved in the use of robotics in organ transplantation research, the United States of America leads robotic organ transplantation studies. The American Journal of Transplantation published the most articles overall.
    CONCLUSION: Based on publication and citation numbers, robotic organ transplantation techniques are becoming more global attention. This robotic abdominal organ transplant surgery bibliometric analysis review covers research output and hotspots.
    Keywords:  VOSviewer; bibliometric; robotic; transplant surgery
    DOI:  https://doi.org/10.1002/rcs.2527
  11. Am J Transl Res. 2023 ;15(4): 2407-2425
       BACKGROUND AND OBJECTIVE: Age-related hearing loss, also termed presbycusis, is the most prevalent sensory impairment in older adults. Presbycusis research has considerably advanced over the past few decades, however, comprehensive and objective reports on the current state of presbycusis research are lacking. We used bibliometric methods to objectively analyzed the progress of presbycusis research over the past 20 years and to identify the research hotspots and emerging trends in this field.
    METHODS: Eligible literature metadata published between 2002 and 2021 were obtained from the Web of Science Core Collection on September 1, 2022. Bibliometric tools including CiteSpace, VOSviewer, Bibliometrix R Package, Microsoft Excel 2019, and an online bibliometric platform were used to conduct bibliometric and visualized analyses.
    RESULTS: A total of 1,693 publications related to presbycusis were retrieved. The number of publications increased continuously from 2002 to 2021, and the USA occupied the lead position in the field, with the highest research output. The most productive and influential institution, author, and journal were the University of California, Frisina DR of the University of South Florida, and Hearing Research, respectively. Co-citation cluster and trend topics analyses revealed that "cochlear synaptopathy", "oxidative stress", and "dementia" were the predominant foci of presbycusis research. Burst detection of keywords indicated that "auditory cortex" and "Alzheimer's disease" were the newly-emerged aspects.
    CONCLUSION: During the past two decades, presbycusis research has been flourishing. The current research foci are "cochlear synaptopathy", "oxidative stress", and "dementia". "Auditory cortex" and "Alzheimer's disease" may be potential future directions in this field. This bibliometric analysis represents the first quantitative overview of presbycusis research, thus providing valuable references and insights for scholars, medical practitioners, and policymakers concerned with this field.
    Keywords:  Presbycusis; age-related hearing loss; bibliometric analysis; trend; visual analysis
  12. Am J Transl Res. 2023 ;15(4): 2329-2344
       BACKGROUND: Tenosynovitis is an acute or chronic inflammatory reaction of the tendon/tendon sheath. The purpose of this study is to summarize the current status, hotspots, and development trends in tenosynovitis related research.
    METHODS: Data on tenosynovitis from 1999 to 2021 were identified from the Web of Science core collection (WoSCC) database and analyzed using bibliometric software. CiteSpace was utilized to identify the top 25 references with the strongest citation bursts, the top 25 keywords with the strongest citation bursts, the dual-map overlay of journals, and a timeline of keywords. VOSviewer was utilized to conduct co-citation, academic collaboration, and keyword analysis. Microsoft Excel was used to draw relevant charts.
    RESULTS: A total of 4,740 publications were collected in this study. The United States ranked first in terms of the H-index, total citations, and total number of publications. The University of California System, University of London, and UDICE-French Research Universities were the major contributing institutions to tenosynovitis research. The Journal of Hand Surgery-American Volume, Skeletal Radiology, and American Journal of Sports Medicine were the main publishing channels for tenosynovitis-related articles. Moreover, Maffulli, N., Van der Helm-van Mil, Annette H.M., Ostergaard, M. were major contributing authors to tenosynovitis research. Finally, research on nonsurgical treatment for tenosynovitis appears to be a future hot spot.
    CONCLUSION: Overall, the number of publications on tenosynovitis grew over the 1999-2021 period. Our study summarized the research status and global trends of tenosynovitis from multiple angles (i.e., countries, institutions, authors, publications). These considerations are helpful to better understand the research hotspots and development trends in the field.
    Keywords:  CiteSpace; Tenosynovitis; VOSviewer; Web of Science; bibliometrics; research trend
  13. J Pain Res. 2023 ;16 1517-1532
       Background: Transient Receptor Potential Vanilloid 1 (TRPV1) is a heat-activated cation channel modulated by inflammatory mediators, which is closely related to pain and serves as a potential analgesic target. However, the bibliometric analyses summarizing TRPV1 in the field of pain are scarce. This study aims to summarize the current status of TRPV1 in pain and the potential research direction.
    Methods: Articles regarding TRPV1 in the pain field between 2013 and 2022 were extracted from the Web of Science core collection database on 31 December 2022. Scientometric software (VOSviewer and CiteSpace 6.1.R6) were used to perform bibliometric analysis. This study provided data on the trend of the annual outputs, countries/regions, institutions, journals, authors, co-cited references and keywords.
    Results: A total of 2462 publications related to TRPV1 in the field of pain were extracted from 2013 to 2022, which were written by 12,005 authors of 2304 institutions, 68 countries/regions in 686 journals, with 48,723 citations totally. The number of publications has grown rapidly over the past 10 years. Most publications were from the USA and China; the Seoul Natl Univ was the most active institution; Tominaga M published the most papers and Caterina MJ was the most productive co-cited author; The top-contributing journal was Pain; The most cited references was the article authored by Julius D. "Neuropathic pain", "inflammatory pain", "visceral pain" and "migraine" were the most common types of pain in this field. The mechanism of TRPV1 in pain was one of the main research directions.
    Conclusion: This study presented an overview of the major research directions of TRPV1 in the pain field by bibliometric methods over the past decade. The results could reveal the research trends and the hotspots in the field and provide helpful information for clinical treatments of pain.
    Keywords:  CiteSpace; TRPV1; VOSviewer; bibliometric analysis; pain
    DOI:  https://doi.org/10.2147/JPR.S407384
  14. Int J Impot Res. 2023 May 17.
      This study aimed to summarize the characteristics of the top 100 most-cited publications on Peyronie's disease (PD) research and to analyse past and current research hotspots and trends. The SCI-E database of the Web of Science Core Collection (WoSCC) provided us with the top 100 most-cited publications in PD research, from which we took the following information: general trend of publication, year of publication, nation/region, institution, journal, author, and keywords. VOSviewer (version 1.6.18) and Excel (version 2016) were used for information analysis. Through a standardized search, we ultimately found 1019 papers in the field of PD research, from which we extracted the 100 articles that had received the highest citations. The articles were published between 1949 and 2016. The United States is a major contributor to PD research (n = 67). The University of California, Los Angeles, was the institution with the largest number of articles (n = 11). These articles were published in 16 journals, with the largest number appearing in the Journal of Urology (n = 47). The author with the most articles was Levine LA (n = 9). Gelbard MK's articles had the highest citation frequency (n = 1158). Erectile dysfunction (n = 19) was the keyword with the highest frequency, indicating that PD-related erectile dysfunction was the leading focus of research in this field. Most of the keywords that have appeared in the past decade are related to the clinical treatment of PD. Therefore, we believe that improving patients' erectile function to the greatest extent in clinical treatment is the frontier and hot spot of future research.
    DOI:  https://doi.org/10.1038/s41443-023-00703-7
  15. Laryngoscope. 2023 May 18.
       OBJECTIVES: As research in otolaryngology continues to expand rapidly, it is important to identify core journals to keep clinicians updated with the latest advances. This study is the first to characterize core journals in otolaryngology.
    METHODS: Using h-index and impact factor (IF), the top 15 NLM-indexed otolaryngology journals were selected for analysis. The references from all articles published in these journals in one randomized quarter were compiled into a citation rank list, with the most cited journal ranked the highest. Citation zonal distribution analysis was conducted to identify the zonal distribution of otolaryngology journals.
    RESULTS: A total of 3150 journals containing 26876 articles were cited in otolaryngology literature in April-June 2019. Laryngoscope was the most cited journal containing 1762 citations. IF is significantly associated with the h-index for the top 10 otolaryngology journals (p = 0.032). Three core journal zones were identified, with Zone 1 containing 8 journals, Zone 2 containing 36 journals, and Zone 3 containing 189 journals. A linear relationship between the log journal rank for Zones 1-3 and a cumulative number of citations was found (R2  = 0.9948).
    CONCLUSION: Eight core journals for otolaryngology were identified: Laryngoscope, Otolaryngology-Head and Neck Surgery, Otology & Neurotology, JAMA Otolaryngology-Head & Neck Surgery, Head & Neck, European Archives of Oto-Rhino-Laryngology, International Journal of Pediatric Otorhinolaryngology, Annals of Otology, Rhinology & Laryngology. In the face of rapidly evolving research and a multitude of journals, the high citation density within these core journals highlights their utility in updating busy clinicians.
    LEVEL OF EVIDENCE: NA Laryngoscope, 2023.
    Keywords:  Bradford's law; core journals; otolaryngology
    DOI:  https://doi.org/10.1002/lary.30709
  16. Environ Sci Pollut Res Int. 2023 May 18.
      In recent years, microplastics have become an integral part of the terrestrial and aquatic environments, which is one of the major concerns of communities around the world. Therefore, it is necessary to know the current status of studies and feasible potentials in the future. This study, conducted an in-depth bibliometric analysis of publications from 1990 to 2022 to present the influential countries, authors, institutes, papers, and journals on microplastics. Findings reveal that there has been a steady increase in microplastic publications and citations in recent years. And, the number of publications and citations has increased 19 and 35 times since 2015. Besides, we performed a comprehensive keyword analysis to show the significant keywords and clusters in this field. In particular, this study used the TF-IDF method as a text-mining analysis to extract the new keywords used in recent years (i.e., 2020-2022). New keywords can draw the attention of scholars to important issues and provide a basis for future research directions.
    Keywords:  Bibiometrix; Bibliometric; Microplastic; Trend analysis; VOSviewer
    DOI:  https://doi.org/10.1007/s11356-023-27647-1
  17. Angle Orthod. 2023 May 17.
       OBJECTIVES: To identify and analyze the 50 most cited articles on temporary anchorage devices (TADs) and investigate the achievement and development of scientific research about the topic through a bibliometric analysis.
    MATERIALS AND METHODS: On August 22, 2022, a computerized database search was performed to detect papers published in the scientific literature about TADs from 2012 to 2022. Metrics data were identified using the Incites Journal Citation Reports (Clarivate Analytics) data set. The Scopus database was used to obtain information on the authors' affiliations, country of origin, and h-index. Key words were automatically harvested from the selected articles to implement the visualized analysis.
    RESULTS: From a total of 1858 papers screened by searching the database, a list of the top 50 most cited articles was created. The total number of citations collected by the 50 most cited articles in TADs was 2380. Among the 50 most cited articles on TADs, 38 were original research papers (76.0%) and 12 were reviews (24.0%). As shown by the key word-network analysis, Orthodontic anchorage procedure was identified as the larger node.
    CONCLUSIONS: Findings of this bibliometric study showed an increasing number of citations for papers on TADs, accompanied by a simultaneous rise in scientific interest in this topic in the past decade. The present work identifies the most influential articles, emphasizing the journals, the authors, and the topics addressed.
    Keywords:  Bibliometric analysis; Miniscrew; Network analysis; Skeletal anchorage; Temporary anchorage devices
    DOI:  https://doi.org/10.2319/010923-18.1
  18. J Clin Densitom. 2023 May 09. pii: S1094-6950(23)00031-8. [Epub ahead of print]26(3): 101381
      The bibliometric analysis assesses the productivity of scholarship in a given field and provides information on the frontiers of relevant developments. However, no bibliometric analysis study has quantitatively analyzed publications in geriatric sarcopenia therapies. This study investigates the scholarly productivity and frontiers of publications in geriatric sarcopenia therapies. The bibliometric data came from English-language Web of Science Core Collection articles published between 1995 and October 19, 2022. Three software programs, R version 3.5.6, VOSviewer, and CiteSpace, were applied for this bibliometric analysis. In twenty-eight years, the annual publications in geriatric sarcopenia therapies have increased yearly, with an annual growth rate of 21.23 %. A total of 1379 publications have been published. The United States was the country with the highest number of publication signatures (n=1,537) (including joint publication releases), followed by Japan (n=1099). Journal of Cachexia, Sarcopenia, and Muscle contributed the best journal publications (n=80). The newest hot subjects in the study about geriatric sarcopenia therapy include malnutrition, obesity, insulin resistance, and cancer. This bibliometric study presents a comprehensive overview of the current and future research directions in geriatric sarcopenia therapies over the past 28 years. Overall, this study has complemented the gaps in bibliometric analysis in geriatric sarcopenia therapies. This paper will provide a valuable reference for future research in geriatric sarcopenia therapies.
    Keywords:  Bibliometrics; Geriatric sarcopenia; Therapies; Web of Science
    DOI:  https://doi.org/10.1016/j.jocd.2023.101381
  19. CNS Neurol Disord Drug Targets. 2023 May 18.
       BACKGROUND: Bibliometric analysis allows us to quantify and evaluate scientific activity, and it has become increasingly important in all areas of scientific literature. Thanks to these analyses, we can infer where science should put greater efforts into elucidating the underlying mechanisms of diseases that have yet to be fully described or investigated.
    OBJECTIVE: This paper delves into published articles related to the involvement of calcium (Ca2+) channels in epilepsy, which is a condition with a high prevalence in Latin America.
    METHODS: We followed the scientific publication on SCOPUS and analyzed the impact of publications from Latin America in the field of epilepsy and the study of Ca2+ channels. We identified the countries with the largest number of publications and found that 68% of them were experimental (animal models), while 32% were clinical. We also identified the main journals, growth over time, and citation numbers.
    RESULTS: We found a total of 226 works produced by Latin American countries from 1976 to 2022. The countries that have contributed the most to the topic are Brazil, Mexico, and Argentina, with occasional collaborations between them to make contributions to the study of epilepsy and Ca2+ channels. Additionally, we found that the journal with the most citations is Nature Genetics.
    CONCLUSION: The number of authors per article ranges from 1 to 242, and neuroscience journals are the preferred target for researchers, with a predilection for publishing original articles, although 26% of the publications are review articles.
    Keywords:  Ca2+; bibliometric; calcium; channel; epilepsy; seizure
    DOI:  https://doi.org/10.2174/1871527322666230518115952
  20. Front Vet Sci. 2023 ;10 1157683
      Publications are an important measure of scientific and technological progress. The quantitative examination of the number of publications in a certain research topic is known as bibliometrics. Bibliographic studies are widely used to analyse the condition of research, future potential, and current growth patterns in a certain topic. It can serve as a basis for making decisions and implementing strategies to achieve long-term development goals. To our knowledge, no research has been conducted in these domains; so, this work aims to employ bibliometric analysis to provide comprehensive data on publications related to anticoccidial drugs. As a result, the current study uses bibliometric analysis to track the evolution of anticoccidial drugs and its consequences in the academic and public worlds via a survey of relevant scientific and popular publications. The Dimensions database was used to retrieve the bibliographical statistics, which were then cleaned and analyzed. The data was also loaded into the VOS viewer, which generated a network visualization of the authors with the most joint articles. The investigation discovered three stages of publications and citations since the first article on anticoccidial drugs in 1949. The first stage, which ran from 1920 to 1968, was characterized by a scarcity of research articles on anticoccidial drugs. From 1969 to 2000, the second stage was marked by a stable and marginally increased number of articles. The scientific field was characterized by an increasing trend in the number of publications and their citations from 2002 to 2021. The study gave a complete list of the top anticoccidial drugs funding agents, countries, research institutes, most cited publications, and important co-authorship and partnerships. The outcomes of the study will help veterinary practitioners and researchers understand the trends and best sources of knowledge in the field of anticoccidial medications.
    Keywords:  analysis; anticoccidial; bibliometric; publications; research
    DOI:  https://doi.org/10.3389/fvets.2023.1157683
  21. Int J Ophthalmol. 2023 ;16(5): 800-810
       AIM: To perform a bibliometric analysis in the field of primary angle-closure disease (PACD) research to characterize current global trends and compare contributions from different countries, institutions, journals, and authors.
    METHODS: All PACD-related publications from 1991 to 2022 from the Web of Science Core Collection database were extracted. Microsoft Excel and VOSviewer were used to collect publication data, analyze publication trends, and visualize relevant results.
    RESULTS: A total of 1721 publications with 34 591 citations were identified. China produced the most publications (554) while ranking third in citations (8220 times). The United States contributed the most citations (12 315 times) with publications (362) ranking second. The Investigative Ophthalmology Visual Science was the most productive journal concerning PACD, and Aung Tin was the author with the highest number of publications in the field. Keywords were classified into three clusters, epidemiology and pathogenesis research, optical coherence tomography (OCT) and other imaging examinations, and glaucoma surgery treatment. Genome-wide association, susceptibility loci, OCT, and combined phacoemulsification have become new hot research topics in recent years since 2015.
    CONCLUSION: China, the United States, and Singapore make the most outstanding contributions in the field of PACD research. OCT, combined phacoemulsification, and gene mutation-related study, are considered the potential focus for future research.
    Keywords:  bibliometric analysis; citations; primary angle-closure disease; publication trends
    DOI:  https://doi.org/10.18240/ijo.2023.05.19
  22. Front Immunol. 2023 ;14 1160048
       Background: Immune thrombocytopenia (ITP) is an autoimmune disease characterized by isolated thrombocytopenia. Recently, the pathophysiology and novel drugs of ITP have been the focus of researchers with plenty of publications emerging. Bibliometrics is the process of extracting measurable data through statistical analysis of published research studies to provide an insight into the trends and hotspots.
    Objective: This study aimed to provide an insight into developing trends and hotspots in the field of ITP by bibliometric analysis.
    Methods: By using three bibliometric mapping tools (bibliometrix R package, VOSviewer, CiteSpace), we summarized the overview information of retrieved publications, as well as the analysis of keyword co-occurrence and reference co-citation.
    Results: A total of 3299 publications with 78066 citations on ITP research were included in the analysis. The keyword co-occurrence network identified 4 clusters relating to the diagnosis, pathophysiology, and treatment of ITP respectively. Then the reference co-citation analysis produced 12 clusters with a well-structured and highly credible clustering model, and they can be divided into 5 trends: second-line treatment, chronic ITP, novel therapy and pathogenesis, COVID-19 vaccine. Treg cells, spleen tyrosine kinase, and mesenchymal stem cells were the latest hotspots with strong burstness.
    Conclusion: This bibliometric analysis provided a comprehensive insight into research hotspots and trends on ITP, which would enrich the review of the ITP research.
    Keywords:  VOSviewer; bibliometric analysis; citespace; immune thrombocytopenia; research hotspot and trends
    DOI:  https://doi.org/10.3389/fimmu.2023.1160048
  23. Transl Cancer Res. 2023 Apr 28. 12(4): 848-858
       Background: To identify the 100 most-cited papers that have contributed to the understanding and treatment of nasopharyngeal carcinoma (NPC).
    Methods: We searched the NPC-related papers between 2000 and 2019 using the Web of Science database on October 12, 2022. Papers were identified in descending order according to the number of citations. The top 100 papers were analyzed.
    Results: These 100 most cited papers on NPC have been cited for a total of 35,273 times, with a median number of citations of 281 times. There were 84 research papers and 16 review papers. The Journal of Clinical Oncology (n=17), International Journal of Radiation Oncology Biology Physics (n=13), and Cancer Research (n=9) published the most papers. Cancer Epidemiology Biomarkers & Prevention, Lancet, Cancer Cell, Molecular Cancer, and the New England Journal of Medicine had the largest average citations per paper. China contributed the most papers (n=71), followed by USA (n=13), Singapore (n=4) and, France (n=4). There were 55 clinical research papers and 29 laboratory research papers. Intensity-modulated radiation therapy technology (n=13), concurrent chemoradiotherapy (n=9), and neoadjuvant chemoradiotherapy (n=5) were the top three research topics. Epstein-Barr virus-related genes (n=9) and noncoding RNA (n=8) were the research domains in laboratory research papers. The top three contributors were Jun Ma (n=9), Anthony T C Chan (n=8), and Anne Wing-Mui Lee (n=6).
    Conclusions: This study provides an overview of the major areas of interest in the field of NPC with bibliometric analyses. This analysis recognizes some important contributions in the field of NPC and stimulates future investigations in the scientific community.
    Keywords:  Nasopharyngeal carcinoma (NPC); Web of Science (WoS); bibliometric analysis; citation analysis
    DOI:  https://doi.org/10.21037/tcr-22-2621
  24. Int J Chron Obstruct Pulmon Dis. 2023 ;18 765-783
       Background: The pathogenesis of chronic obstructive pulmonary disease (COPD) has been studied in relation to the microbiome, providing space for more targeted interventions and new treatments. Numerous papers on the COPD microbiome have been reported in the last 10 years, yet few publications have used bibliometric methods to evaluate this area.
    Methods: We searched the Web of Science Core Collection for all original research articles in the field of COPD microbiome from January 2011 to August 2022 and used CiteSpace for visual analysis.
    Results: A total of 505 relevant publications were obtained, and the number of global publications in this field is steadily increasing every year, with China and the USA occupying the first two spots in international publications. Imperial College London and the University of Leicester produced the most publications. Brightling C from the UK was the most prolific writer, while Huang Y and Sze M from the USA were first and second among the authors cited. The American Journal of Respiratory and Critical Care Medicine had the highest frequency of citations. The top 10 institutions, cited authors and journals are mostly from the UK and the US. In the ranking of citations, the first article was a paper published by Sze M on changes in the lung tissue's microbiota in COPD patients. The keywords "exacerbation", "gut microbiota", "lung microbiome", "airway microbiome", "bacterial colonization", and "inflammation" were identified as cutting-edge research projects for 2011-2022.
    Conclusion: Based on the visualization results, in the future, we can use the gut-lung axis as the starting point to explore the immunoinflammatory mechanism of COPD, and study how to predict the effects of different treatments of COPD by identifying the microbiota, and how to achieve the optimal enrichment of beneficial bacteria and the optimal consumption of harmful bacteria to improve COPD.
    Keywords:  COPD; CiteSpace; bacterial colonization; bibliometric analysis; gut microbiome; microbiome; respiratory microbiome
    DOI:  https://doi.org/10.2147/COPD.S405310
  25. Front Oral Health. 2023 ;4 1059023
       Background: The aim of the study was to assess gender differences in the productivity, impact, collaboration pattern and author position of dentistry and oral sciences researchers in Nigeria.
    Methods: We examined the Web of Science (WoS) publication records of dentistry and oral sciences researchers to assess gender differences in productivity, impact, collaboration and authorship pattern (first authorship, last authorship and corresponding author). The analysis included the number of publications in journals ranked based on their quartile rating amongst the journals in the subject area (Q1-Q4). Chi square was used to make gender comparisons. Significance was set at >5%.
    Results: 413 unique authors published 1,222 articles on dentistry and oral sciences between 2012 and 2021. The number of WoS documents per female author was significantly higher than that per male author (3.7 vs. 2.6, p = 0.03). A non-significantly higher percentage of females authored papers in Q2 and Q3 journals and a higher percentage of males authored papers in Q4 journals. The number of citations per female author (25.0 vs. 14.9, p = 0.04) and the percentage of females listed as first authors (26.6% vs. 20.5%, p = 0.048) were statistically greater than men. The percentage of males listed as last authors was statistically greater than females (23.6% vs. 17.7%, p = 0.04). The correlation between the percentage of papers with researchers listed as first authors and that listed as last authors was not significant for males (p = 0.06) but was significant for females (p = 0.002). A non-significantly greater percentage of females were listed as corresponding authors (26.4% vs. 20.6%) and males were listed as international (27.4% vs. 25.1%) and domestic collaborators (46.8% vs. 44.7%). Also, there was no statistically significant gender difference in the proportion of articles published in open access journals (52.5% vs. 52.0%).
    Conclusion: Though there were significant gender differences in the productivity, impact, and collaboration profile of dentistry and oral sciences researchers in Nigeria, the higher female research productivity and impact may be driven by cultural gender nuances that needs to be explored further.
    Keywords:  author position; collaboration pattern; dentistry and oral sciences research; open access publishing; papers published; total citations
    DOI:  https://doi.org/10.3389/froh.2023.1059023
  26. J Trauma Acute Care Surg. 2023 May 15.
       BACKGROUND: Bibliometric analysis of surgical research has become increasingly prevalent. Citation count (CC) is a commonly utilized marker of research quality, but may overlook impactful military research. The disruption score (DS) evaluates manuscripts on a spectrum from most innovative with more positive scores (disruptive; DR) to most entrenched with more negative scores (developmental; DV). We sought to analyze the most DR and DV versus most cited research in military trauma.
    METHODS: Top trauma papers by DS and by CC were identified via professional literature search. All publications in military journals were included. Military trauma-related keywords were used to query additional top surgical journals for military-focused publications. Publications were linked to the iCite NIH tool for CC and related metrics. The top 100 DR and DV publications by DS were analyzed and compared to the top 100 papers by CC.
    RESULTS: Overall, 32,040 articles published between 1954-2014 were identified. The average DS and CC were 0.01 and 22, respectively. Most papers were published in Mil Med (68%). The top 100 DR papers were frequently published in Mil Med (51%) with a mean DS of 0.148. Of these, the most cited article was only the 40th most disruptive. The top 100 CC papers averaged a DS of 0.009 and were commonly found in J Trauma (53%). Only 5 publications were on both the top 100 DR and top 100 CC lists; 19 were on both the top DV and CC lists. CC was not correlated with DR (r = -.134; p = .07) and only weakly correlated with DV (r = .215; p = .003).
    CONCLUSION: DS identifies publications that changed military paradigms and future research directions previously overlooked by citation count alone. DR and DV papers are distinct with little overlap between highly cited military papers. Multiple bibliometric measures should be employed to avoid overlooking impactful military trauma research.Study Type: original researchLevel of Evidence: N/A.
    DOI:  https://doi.org/10.1097/TA.0000000000004009
  27. Braz Dent J. 2023 Mar-Apr;34(2):pii: S0103-64402023000200041. [Epub ahead of print]34(2): 41-55
      This study analyzes the characteristics of the top 100 most-cited papers related to tooth bleaching. A literature search was performed on the Web of Science up to March 2022. The number of citations was cross-matched with the citation count on Scopus and Google Scholar. The following data were collected: number and density of citations; authorship; year and journal of publication; study design and thematic; keywords; institution and country of origin. Spearman's correlation and Poisson regression were used to determine associations between the number of citations and study characteristics. The VOSviewer software was used to generate collaborative network maps for the authors and keywords. The number of citations ranged from 66 to 450. Papers were published between 1981 and 2020. The most frequent study design and topic were laboratory-based studies and 'interaction of the bleaching agent with dental tissues', respectively. Cochran M, Loguercio AD, Matis B, Reis A, and Suliman M were the authors with the highest number of papers. The countries with the most papers were the United States of America (USA) (28%) and Brazil (20%). Indiana University and State University of Ponta Grossa were the institutions with the most papers (6% each). There was a very strong correlation among the number of citations of the three databases. The 100 most-cited papers related to tooth bleaching were mainly published by the USA and Brazil, with laboratory-based studies addressing topics related to the effects of bleaching agents on tooth structure being the most prevalent.
    DOI:  https://doi.org/10.1590/0103-6440202305290
  28. J Thorac Dis. 2023 Apr 28. 15(4): 1684-1693
       Background: Sepsis is one of the main causes of death in critically ill patients. Immunosuppression was involved deeply in the process of sepsis. The status of research on sepsis-related immunosuppression remains unclear. In this study, a bibliometric analysis was conducted to provide a preliminarily analysis of the current research status in sepsis-related immunosuppression.
    Methods: The Science Citation Index Expanded (SCI-E) database in the Web of Science Core Collection was used as the data source for the literature search, and the time was set from the inception of the database to the last retrieval time for this study (i.e., May 21, 2022). Using the topic search, we searched for "sepsis" and then for "immunosuppression" in the results to obtain the final results. On the search page of the SCI-E database, we selected the document type, topic direction, MeSH topic heading, MeSH qualifier, keywords, author, journal, country, research institution, language, etc., to obtain the distribution results, and manually removed any duplicate records. We analyzed the use of keywords in the literature and the centrality of the authors, countries, and research institutions.
    Results: A total of 4,132 articles were retrieved from the database over the search period of 1900 to May 21, 2022. The number of articles published increased annually. A trend of rapid growth was also observed in the number of citations. The most common topic words were humans, male, and female. The most used keywords were sepsis, immunosuppression, and male. The most published researcher was Monneret from Lyon, France. The authors of the article mainly specialized in immunology and surgery. Moldawer and Chaudry from the United States (US) had engaged in the most collaborations with other researchers. The journals that publish literature in this field are mainly journals related to critical care medicine, and the core journals included Shock, Critical Care, and Critical Care Medicine.
    Conclusions: More and more studies are being published on sepsis-related immunosuppression and largely being conducted in developed countries. Chinese researchers need to carry out more collaborative research.
    Keywords:  Sepsis; bibliometric analysis; immunosuppression
    DOI:  https://doi.org/10.21037/jtd-23-300
  29. Indian J Ophthalmol. 2023 May;71(5): 2152-2157
       Purpose: The research activity in pediatric glaucoma (PG) was qualitatively and quantitatively evaluated using a scientometric approach.
    Methods: The "Web of Science" database was accessed for primary bibliometric data regarding PG using search terms "pediatric glaucoma," "paediatric glaucoma," "congenital glaucoma," and "childhood glaucoma." The data was analyzed for total research productivity, citations, and scientific output in terms of journals, countries, institutions, and authors. The results were further characterized for coauthorship links and visualized by VOS viewer software. Also, the top 25 cited articles were reviewed with the above bibliometric characteristics.
    Results: One thousand two hundred and sixty-nine items were obtained from our search query from 1955 to 2022; these received 15,485 citations, originated from 78 countries. The top-3 contributing countries were the United States of America (n = 369), India (n = 134), and China (n = 127). LV Prasad Eye Institute (n = 58), Duke University (n = 44), and King Khalid Eye Specialist Hospital (n = 42) were the top-3 productive institutes. The top-3 prolific authors were Mandal AK (n = 53), Freedman, SF (n = 36), and Sarfarazi, M (n = 33). Journal wise, "Investigative Ophthalmology" (n = 187), "Journal of Glaucoma" (n = 92), and "Journal of AAPOS" (n = 68) were the journals in which the most articles were published. The top-25 cited documents received 3564 citations and were published between 1977 and 2016. The key areas of interest were basic sciences (genetics of childhood glaucoma) and surgical management.
    Conclusion: United States of America, LVPEI, Mandal AK, and "Investigative Ophthalmology" were the top rankers as far as the productivity and publications related to PG are concerned. Articles on molecular genetics in PG have received interest among the ophthalmology community.
    Keywords:  Childhood glaucoma; congenital glaucoma; pediatric glaucoma
    DOI:  https://doi.org/10.4103/IJO.IJO_2998_22
  30. Front Psychiatry. 2023 ;14 1096769
       Background: In recent years, a large number of studies have focused on autism spectrum disorder (ASD). The present study used bibliometric analysis to describe the state of ASD research over the past decade and identify its trends and research fronts.
    Methods: Studies on ASD published from 2011 to 2022 were obtained from the Web of Science Core Collection (WoSCC). Bibliometrix, CiteSpace, and VOSviewer were used for bibliometric analysis.
    Results: A total of 57,108 studies were included in the systematic search, and articles were published in more than 6,000 journals. The number of publications increased by 181.7% (2,623 in 2011 and 7,390 in 2021). The articles in the field of genetics are widely cited in immunology, clinical research, and psychological research. Keywords co-occurrence analysis revealed that "causative mechanisms," "clinical features," and "intervention features" were the three main clusters of ASD research. Over the past decade, genetic variants associated with ASD have gained increasing attention, and immune dysbiosis and gut microbiota are the new development frontiers after 2015.
    Conclusion: This study uses a bibliometric approach to visualize and quantitatively describe autism research over the last decade. Neuroscience, genetics, brain imaging studies, and gut microbiome studies improve our understanding of autism. In addition, the microbe-gut-brain axis may be an exciting research direction for ASD in the future. Therefore, through visual analysis of autism literature, this paper shows the development process, research hotspots, and cutting-edge trends in this field to provide theoretical reference for the development of autism in the future.
    Keywords:  CiteSpace; VOSviewer; autism spectrum disorder; bibliometric study; research frontiers
    DOI:  https://doi.org/10.3389/fpsyt.2023.1096769
  31. Front Aging Neurosci. 2023 ;15 1149143
       Objective: The aim of this study was to identify and characterize the 100 most cited articles on Parkinson's disease (PD) and phenolic compounds (PCs).
    Methods: Articles were selected in the Web of Science Core Collection up to June 2022 based on predetermined inclusion criteria, and the following bibliometric parameters were extracted: the number of citations, title, keywords, authors, year, study design, tested PC and therapeutic target. MapChart was used to create worldwide networks, and VOSviewer software was used to create bibliometric networks. Descriptive statistical analysis was used to identify the most researched PCs and therapeutic targets in PD.
    Results: The most cited article was also the oldest. The most recent article was published in 2020. Asia and China were the continent and the country with the most articles in the list (55 and 29%, respectively). In vitro studies were the most common experimental designs among the 100 most cited articles (46%). The most evaluated PC was epigallocatechin. Oxidative stress was the most studied therapeutic target.
    Conclusion: Despite the demonstrations in laboratorial studies, the results obtained point to the need for clinical studies to better elucidate this association.
    Keywords:  Parkinson’s disease; bibliometric; bibliometric and network analysis; neuroprotection; phenolic compound
    DOI:  https://doi.org/10.3389/fnagi.2023.1149143
  32. Inquiry. 2023 Jan-Dec;60:60 469580231174333
      The purpose of this study is to assess the quantity and quality of myopia related articles from 2001 to 2021 using bibliometric methods. The number of published articles and citations, the correlation analysis between gross domestic product (GDP) and annual publication number and citations was investigated. The proportion of myopia articles from East Asia accounted for 55.28% in 2021. The researchers from China published the most articles on myopia during 2001 to 2021, followed by Japan and South Korea. The annual number of articles and citations from China and South Korea showed an exponential increase with strong positive correlation with GDP. All 3 countries in East Asia are mainly researching refractive surgery, prevalence, and glaucoma, and research on children's myopia is particularly active in China, and in Japan. The researchers from East Asia published more than half of articles on myopia since 2019, in order of China, Japan, and South Korea. The annual number of articles and citations from China and South Korea showed an exponential increase with strong positive correlation with GDP whereas those from Japan did not. All 3 countries are mainly researching refractive surgery, and glaucoma, and research on children's myopia is particularly active in China, and in Japan.
    Keywords:  Asia; China; Eastern; Japan; Republic of Korea; bibliometrics; child; glaucoma; myopia
    DOI:  https://doi.org/10.1177/00469580231174333
  33. JPRAS Open. 2023 Jun;36 85-88
      
    Keywords:  Academic; Plastic surgery; Publication
    DOI:  https://doi.org/10.1016/j.jpra.2023.04.003
  34. Front Endocrinol (Lausanne). 2023 ;14 1145067
       Background: Type 2 diabetes mellitus (T2DM) is a pathological metabolic disorder induced by the interaction of genetic and environmental factors. Epigenetic modifications, especially DNA and RNA methylation, might be the bridge between hereditary and environmental factors. This study aimed to comprehensively analyze the status and prospective trends of the association between T2DM and DNA/RNA methylation modifications by using bibliometric software.
    Methods: All the publications in the Web of Science database for the research of T2DM with DNA and RNA methylation modifications were obtained from the earliest mention to December 2022. CiteSpace software was used to analyze countries, institutions, journals/cited-references, authors/cited-authors, and keywords. Results of the comprehensive visualization and bibliometric analysis were displayed relative to the research hotspots and knowledge structure.
    Results: A total of 1,233 publications related to DNA and RNA methylation modifications and T2DM were collected. The number of publications per year and the overall trend consistently and significantly increased during the investigation period. Based on the highest publication counts, the most influential country was the USA, while Lund University was the most productive institution. DIABETES was considered the most popular journal. The most frequent keywords identified in the field of methylation and T2DM were mainly involved in developmental origin, insulin resistance, and metabolism. The study suggested that the study of methylation modifications had an increasingly significant role in understanding the progression of T2DM.
    Conclusion: CiteSpace visualization software was utilized to investigate the status and trends of DNA and RNA methylation modifications in the pathology of T2DM over the past 30 years. Findings from the study provide a guiding perspective for researchers regarding future research directions in this field.
    Keywords:  CiteSpace; DNA methylation; RNA methylation; bibliometrics; type 2 diabetes mellitus
    DOI:  https://doi.org/10.3389/fendo.2023.1145067
  35. Front Cell Dev Biol. 2023 ;11 1178221
      Background: Gene editing tools using clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-related systems have revolutionized our understanding of cancer. The purpose of this study was to determine the distribution, collaboration, and direction of cancer research using CRISPR. Methods: Data from the Web of Science (WoS) Core Collection database were collected from 4,408 cancer publications related to CRISPR from 1 January 2013to 31 December 2022. The obtained data were analyzed using VOSviewer software for citation, co-citation, co-authorship, and co-occurrence analysis. Results: The number of annual publications has grown steadily over the past decade worldwide. The United States was shown, by far, to be the leading source of cancer publications, citations, and collaborations involving CRISPR than any other country, followed by China. Li Wei (Jilin University, China), and Harvard Medical School (Boston, MA, United States) were the author and institution with the most publications and active collaborations, respectively. The journal with the most contributions was Nature Communications (n = 147) and the journal with the most citations was Nature (n = 12,111). The research direction of oncogenic molecules, mechanisms, and cancer-related gene editing was indicated based on keyword analysis. Conclusion: The current study has provided a comprehensive overview of cancer research highlights and future trends of CRISPR, combined with a review of CRISPR applications in cancer to summarize and predict research directions and provide guidance to researchers.
    Keywords:  CAS; CRISPR; bibliometrics; cancer; immunotherapy
    DOI:  https://doi.org/10.3389/fcell.2023.1178221
  36. J Stomatol Oral Maxillofac Surg. 2023 May 17. pii: S2468-7855(23)00134-9. [Epub ahead of print] 101513
       OBJECTIVES: Odontogenic infections are common and a topic of core interest for dentists, and maxillofacial surgeons. The aim of this study was to conduct a bibliometric analysis of the global literature on odontogenic infection and explore the top 100 most cited papers to identify the common causes, sequelae and management trends.
    METHODS: Following a comprehensive literature search, a list of top 100 most cited papers was created. The VOSviewer software (Leiden University, The Netherlands) was used to create a graphical representation of the data, and statistical analyses were performed to analyze the characteristics of the top 100 most cited papers.
    RESULTS: A total of 1,661 articles were retrieved with the first article published in 1947. There is an exponential upward trend on the number of publications (R2 = 0.919) and a majority of papers are in English language (n = 1,577, 94.94%). A total of 22,041 citations were found with a mean of 13.27 per article. The highest number of publications were recorded from developed countries. There was a male predilection in the reported cases and the most common sites included the submandibular and parapharyngeal spaces. Diabetes mellitus was identified as the commonest co-morbidity. Surgical drainage was ascertained to be the preferred method of management.
    CONCLUSIONS: Odontogenic infections remain prevalent and have a global distribution. Although prevention of odontogenic infection through meticulous dental care is ideal, early diagnosis and prompt management of established odontogenic infections is important to avoid morbidities and mortality. Surgical drainage is the most effective management strategy. There is lack of consensus regarding the role of antibiotics in the management of odontogenic infections.
    Keywords:  Bibliometrics; Citation Analysis; Odontogenic Infections; Top-cited articles
    DOI:  https://doi.org/10.1016/j.jormas.2023.101513
  37. Int J Med Mushrooms. 2023 ;25(5): 31-48
      This paper aims to characterize the knowledge field of Grifola frondosa and analyze its research themes and trends. CiteSpace, a powerful bibliometric analysis tool, was adopted to visualize the knowledge field of G. frondosa research for facilitating this current study. A total of 747 articles and reviews retrieved from the Web of Science Core Collection (WoSCC) database between 1998 and 2022 were analyzed by CiteSpace. It was found that China and Japan are the most influential countries in G. frondosa research. Secondly, polysaccharide, bioactivity, structural characterization, and submerged culture are the main themes of G. frondosa research, among which bioactivity and structural characterization are the current research hotspots. Finally, selenium polysaccharide and gut microbiota may be the emerging trends in G. frondosa research in the future. This study could help researchers discern the evolution and future trends of G. frondosa research and provide a reference for related research work.
    DOI:  https://doi.org/10.1615/IntJMedMushrooms.2023047962
  38. PLoS One. 2023 ;18(5): e0284866
      One of the main factors that attracts authors to choose a journal is the time interval between submission and publication, which varies between journals and subject matter. Here, we evaluated the time intervals between submission and publication according to journal impact factor and continent of author's affiliation, considering articles with authors from single or multiple continents. Altogether, 72 journals indexed in the Web of Science database within the subject matter "Genetics and Heredity", divided by impact factor into four quartiles and randomly selected were analyzed for time intervals from article submission to publication. Data from a total of 46,349 articles published from 2016 to 2020 were collected and analyzed considering the following time intervals: submission to acceptance (SA), acceptance to publication (AP) and submission to publication (SP). The median of the quartiles for the SP interval was 166 (IQR [118-225]) days for Q1, 147 (IQR [103-206]) days for Q2, 161 (IQR [116-226]) days for Q3 and 137 (IQR [69-264]) days for Q4, showing a significant difference among quartiles (p < 0.001). In Q4, median interval of time was shorter in interval SA but longer in interval AP, and overall, articles in Q4 had the shortest interval of time in SP. A potential association of the median time interval and authors' continent was analysed and no significant difference was observed between articles with authors from single versus multiple continents or between continents in articles with authors from only one continent. However, in journals from Q4, time from submission to publication was longer for articles with authors from North America and Europe than from other continents, although the difference was not significant. Finally, articles of authors from the African continent had the smallest representation in journals from Q1-Q3 and articles from Oceania were underrepresented in group Q4. The study provides a global analysis of the total time required for submission, acceptance and publication in journals in the field of genetics and heredity. Our results may contribute in the development of strategies to expedite the process of scientific publishing in the field, and to promote equity in knowledge production and dissemination for researchers from all continents.
    DOI:  https://doi.org/10.1371/journal.pone.0284866
  39. Front Psychiatry. 2023 ;14 1136125
       Background: There is a vast amount of evidence-based medicine research on the major depressive disorder (MDD) available in the literature, however, no studies on the overall performance, productivity and impact of such research have been published to date. This study explored and mapped the research outputs of MDD-related systematic reviews and meta-analyses (SR/MA) from a bibliometric perspective.
    Methods: Relevant data were retrieved with search terms on MDD, systematic review and meta-analysis.
    Results: A total of 4,870 papers with 365,402 citations published from 1983 to 2022 were included in the analysis. The publication output has grown steadily over time with the most publications originating from the USA (1,020; 20.94%), the UK (516; 10.60%) and China (448; 9.20%). The research collaborations between countries were most frequent between the USA and UK (266; 5.46%). Journal of Affective Disorders (379; 7.78%) was the most productive journal, while Cuijpers P was the most productive author (121; 2.48%), and University of Toronto (569; 11.78%) was the most productive institution. The top 10 most cited articles on MDD-related SR/MA had citations ranging from 1,806 to 3,448. The high-frequency keywords were mainly clustered into four themes, including psychiatric comorbidities, clinical trials, treatment, and brain stimulation in MDD.
    Conclusion: The rapid increase in the number of SR/MA of MDD in recent years highlights the importance of this research field. Psychiatric comorbidities, clinical interventions, and treatment of MDD have been identified as hot topics, while biological mechanisms in MDD are likely to be an emerging research priority.
    Keywords:  bibliometric analysis; depression; evidence-based medicine research; meta-analysis; systematic review
    DOI:  https://doi.org/10.3389/fpsyt.2023.1136125
  40. Children (Basel). 2023 Mar 30. pii: 660. [Epub ahead of print]10(4):
      Regular physical activity (PA) is an essential component of maintaining good health, thereby improving the physical and psychological well-being of the population. PA performed during childhood and adolescence can have repercussions in adulthood, contributing to the prevention of chronic activities and improving quality of life. Given its high relationship with PA, physical literacy could play a crucial role in valuing and participating in a physically active lifestyle, thus addressing low rates of PA participation from an early age. This bibliometric analysis provides a globalized view of physical literacy (PL) and its relationship with health, pathologies, prevention, or intervention among children and adolescents. Publications registered on Web of Science were analyzed using bibliometrics based on data from 141 documents published between 2014 and 2022, while the VOSviewer software v. 1.6.18. was used for the processing and visualization of the data and metadata. The results show an exponential growth in scientific research over the last 8 years, with an accumulation of documents in four journals and a distribution of publications spanning thirty-seven countries and regions. The network of researchers consists of 500 researchers, with the largest number of publications corresponding to 18 co-authors with at least 5 publications. The principal purpose of this research was to identify the most prolific co-authors, most-cited journals and co-authors, and the most relevant keywords.
    Keywords:  bibliometric; healthy behavior; monitoring; physical activity
    DOI:  https://doi.org/10.3390/children10040660
  41. Sleep Med. 2023 May 03. pii: S1389-9457(23)00171-5. [Epub ahead of print]107 164-170
      We conducted the first scientometric analysis to quantitatively assess the scientific contribution of researchers from Italian institutions in the field of pediatric sleep medicine. We searched Science Citation Index Expanded from Web of Science (WOS) Science Citation up to November 3rd, 2022. Bibliometrix R packages (3.1.4) and CiteSpace (6.0.R2) were used to extract and analyze co-citation reference networks, co-occurring keyword networks, co-authorship network, co-cited institutions, and co-cited journals. We retrieved a total of 2499 documents, published between 1975 and 2022. Co-cited reference networks showed four main clusters of highly cited topics: evidence synthesis of publications on sleep disorders in children and adolescents, sleep and neurological disorders, non-pharmacological treatments of sleep disturbances, and sleep and Covid-19 in youth. Co-occurring keyword networks showed an earlier focus on the neurophysiology of sleep/neurological disorders, followed by a trend on the association of sleep disturbances to neurodevelopmental disorders and behavioral aspects. Co-authorship network showed that Italian researchers in the field of pediatric sleep medicine tend to be highly collaborative internationally. Overall, Italian researchers have provided a crucial contribution to pediatric sleep medicine across a number of specific topics, spanning from neurophysiology to treatment, and from neurological to behavioral/psychopathological aspects.
    Keywords:  Adolescents; Children; Italy; Scientometric; Sleep
    DOI:  https://doi.org/10.1016/j.sleep.2023.05.002
  42. Biomed Tech (Berl). 2023 Apr 27.
       OBJECTIVES: Electroporation, the breakdown of the biomembrane induced by external electric fields, has increasingly become a research hotspot for its promising related methods in various kinds of cancers.
    CONTENT: In this article, we utilized CiteSpace 6.1.R2 to perform a bibliometric analysis on the research foundation and frontier of electroporation-based applications in cancer therapy. A total of 3,966 bibliographic records were retrieved from the Web of Science Core Collection for the bibliometric analysis. Sersa G. and Mir L. M. are the most indispensable researchers in this field, and the University of Ljubljana of Slovenia is a prominent institution. By analyzing references and keywords, we found that, with a lower recurrence rate, fewer severe adverse events, and a higher success rate, irreversible electroporation, gene electrotransfer, and electrochemotherapy are the three main research directions that may influence the future treatment protocol of cancers.
    SUMMARY: This article visualized relevant data to synthesize scientific research on electroporation-based cancer therapy, providing helpful suggestions for further investigations on electroporation.
    OUTLOOK: Although electroporation-based technologies have been proven as promising tools for cancer treatment, its radical mechanism is still opaque and their commercialization and universalization need further efforts from peers.
    Keywords:  bibliometrics; cancer treatment; citespace; electroporation
    DOI:  https://doi.org/10.1515/bmt-2023-0113
  43. J World Fed Orthod. 2023 May 17. pii: S2212-4438(23)00039-5. [Epub ahead of print]
       BACKGROUND: To study the relation between social media mentions and academic citations for articles published in peer-reviewed orthodontic journals.
    METHODS: Articles published in early 2018 in seven peer-reviewed orthodontic journals were retrospectively analyzed in September 2022. Citation counts of the articles were evaluated using two databases: Google Scholar (GS) and Web of Science (WoS). The Altmetric Attention Score, Twitter, Facebook mentions, and Mendeley reads were tracked using the Altmetric Bookmarklet. The citation counts and social media mentions were correlated using Spearman rho.
    RESULTS: A total of 84 articles were identified during the initial search; 64 (76%) were original studies and systematic review articles and included in the analysis. A total of 38% of the articles had at least one mention on social media. Over the study period, the average number of citations of the articles mentioned on social media was higher than the non-mentioned articles for GS and WoS, respectively. Moreover, significant positive correlations existed between the Altmetric Attention Score and the number of citations in GS and WoS (rs = 0.31, P = 0.001 and rs = 0.26, P = 0.04).
    CONCLUSIONS: Social media mentions and citations of articles published in peer-reviewed orthodontic journals are correlated, with a clear difference in the number of citations in articles mentioned on social media versus those not mentioned, indicating possible increased reach of articles disseminated on social media.
    Keywords:  Altmetrics; Citation; Facebook; Google Scholar; Publication; Social media; Twitter; Web of Science
    DOI:  https://doi.org/10.1016/j.ejwf.2023.05.003
  44. Environ Sci Pollut Res Int. 2023 May 19.
      A wildfire, an unplanned fire that is mainly uncontrolled and originates in combustible vegetation in rural or urban settings, is one of the most pervasive natural catastrophes in some areas, such as Siberia, California and Australia. Many studies, such as standard reviews, have been undertaken to look into the works of literature on wildfires or forest fires and their effects on aquatic and terrestrial ecosystems. Regrettably, conventional literature reviews failed to identify the important researchers, evolving complexities, emerging research hotspots, trends and opportunities for further research on the ground of wildfire study. The present study employs bibliometric analysis to investigate this study area qualitatively and quantitatively. The Scopus database systems and Web of Science Core Collection yielded 78 qualifying papers, which were then evaluated using Biblioshiny (A bibliometrix tool of R-studio). According to the statistics, the discipline is expanding at a pace that is 13.68% faster than average. So far, three key periods of transformation have been documented: preliminary evolution (8 articles; 1999-2005), gentle evolution (14 articles; 2006-2013) and quick evolution (56 articles; 2014 to 2021). Forest Ecology and Management and Science journals have the highest number of publications, accounting for 7.70% of total wildfire-related articles published from 1999 to 2021. However, recent data indicate that investigators are shifting their focus to wildfires, with the term 'Australia' having the highest frequency (91) and 'wildfire' having the second highest (58) as the most appeared keywords. The present study will provide a foundation for future research on wildfire incidence and management by receiving information by synthesising previously published literature in Australia and around the world.
    Keywords:  Australia; Bibliometric analysis; Biblioshiny; Bushfire; Wildfire
    DOI:  https://doi.org/10.1007/s11356-023-27423-1
  45. Front Pharmacol. 2023 ;14 1175057
      Background: Irritable bowel syndrome (IBS) is a group of functional intestinal disorders characterized by abdominal pain, bloating, and changes in bowel habits, and/or stool characteristics. Recent studies have shown that there has been a significant advancement in the study of visceral hypersensitivity in IBS. Through the use of bibliometrics, this study aims to provide a comprehensive overview of the knowledge structure and research hotpots of visceral hypersensitivity in IBS. Methods: Publications related to visceral hypersensitivity in IBS from 2012 to 2022 were searched on the web of science core collection (WoSCC) database. CiteSpace.6.1. R2 and Vosviewer 1.6.17 were used to perform bibliometric analysis. Results: A total of 974 articles led by China and the United States from 52 countries were included. Over the past decade, the number of articles on visceral hypersensitivity and IBS has steadily increased year by year. China, the United States, and Belgium are the main countries in this field. Univ Oklahoma, Univ Gothenburg, and Zhejiang University are the main research institutions. Simren, Magnus, Greenwood-van meerveld, Beverley, and Tack, Jan are the most published authors in this research field. The research on the causes, genes, and pathways involved in visceral hypersensitivity in IBS and the mechanism of IBS are the main topics and hotspots in this field. This study also found that gut microbiota may be related to the occurrence of visceral hypersensitivity, and probiotics may be a new method for the treatment of visceral hypersensitivity and pain, which may become a new direction for research in this field. Conclusion: This is the first bibliometric study to comprehensively summarize the research trends and developments of visceral hypersensitivity in IBS. This information provides the research frontier and hot topics in this field in recent years, which will provide a reference for scholars studying this field.
    Keywords:  IBS; bibliometrics; research progress; visceral hypersensitivity; visualized analysis
    DOI:  https://doi.org/10.3389/fphar.2023.1175057
  46. Sci Total Environ. 2023 May 13. pii: S0048-9697(23)02561-5. [Epub ahead of print] 163940
      Gender representation in science has been extensively investigated by scientists from different disciplines and locations. Men continue to publish, collaborate, and obtain more citations than women. We investigated the relationship between Editor-in-Chief (EiC) and Editorial Boards' (EB) gender representation and the impact factor (IF) of environmental science journals (ESJ). We analyzed EiC/EB members of the top ESJ in the Web of Science databases that published at least 10,000 articles from their first publication until 2021. Binary gender information was assigned to 9153 members from 39 journals. IF ranged from 0.854 to 11.236 (x̅=5.05). Women represented 20 % of EiC positions and 23 % of EB members. Although, the majority of female EiC/EBs were represented in journals with an IF lower than the mean. No correlation was found between EiC's gender representation and the IF (p > 0.05). Regarding the hypothesis that female EiC was associated with EB gender equity, the link was not significant (p = 0.3). Our hypothesis of no association between gender proportion and IF was accepted for journals with IF>5 (p = 0.2) but rejected for IF.
    Keywords:  Career; Gender equity; Science; Scientific production; Sexism
    DOI:  https://doi.org/10.1016/j.scitotenv.2023.163940
  47. Curr Probl Cardiol. 2023 May 10. pii: S0146-2806(23)00195-0. [Epub ahead of print] 101778
      I request you to note that this is a letter. Thanks to CPC, which already accepted our earlier letter.
    Keywords:  Authors; Bibliometric Analysis; Cardio-Oncology; Scopus
    DOI:  https://doi.org/10.1016/j.cpcardiol.2023.101778
  48. Ther Innov Regul Sci. 2023 May 18.
       BACKGROUND: Establishing a horizon scanning method is critical for identifying technologies that require new guidelines or regulations. We studied the application of bibliographic citation network analysis to horizon scanning.
    OBJECTIVE: The possibility of applying the proposed method to interdisciplinary fields was investigated with the emphasis on tissue engineering and its example, three-dimensional bio-printing.
    METHODOLOGY AND RESULTS: In all, 233,968 articles on tissue engineering, regenerative medicine, biofabrication, and additive manufacturing published between January 1, 1900 and November 3, 2021 were obtained from the Web of Science Core Collection. The citation network of the articles was analyzed for confirmation that the evolution of 3D bio-printing is reflected by tracking the key articles in the field. However, the results revealed that the major articles on the clinical application of 3D bio-printed products are located in clusters other than that of 3D bio-printers. We investigated the research trends in this field by analyzing the articles published between 2019 and 2021 and detected various basic technologies constituting tissue engineering, including microfluidics and scaffolds such as electrospinning and conductive polymers. The results suggested that the research trend of technologies required for product development and future clinical applications of the product are sometimes detected independently by bibliographic citation network analysis, particularly for interdisciplinary fields.
    CONCLUSION: This method can be applied to the horizon scanning of an interdisciplinary field. However, identifying basic technologies of the targeted field and following the progress of research and the integration process of each component of technology are critical.
    Keywords:  3D bio-printing; Bibliometric; Citation network analysis; Horizon scanning; Regulatory science; Scaffold; Text mining; Tissue engineering
    DOI:  https://doi.org/10.1007/s43441-023-00529-x
  49. J Health Popul Nutr. 2023 May 12. 42(1): 42
       BACKGROUND: During the initial stages of the coronavirus disease 2019 (COVID-19) pandemic, the administration of antibiotics to patients was prevalent in numerous countries. Despite this, the rising threat of antimicrobial resistance (AMR) presents a significant public health concern. The escalation of AMR has been exacerbated by the ongoing COVID-19 pandemic. Against this backdrop, the primary aim of this study was to conduct a bibliometric and visual analysis of research pertaining to the use of antibiotics in COVID-19.
    METHODS: This study examined documents indexed in Scopus between 2020 and 2022. To visualize the trends and hotspots of research related to antibiotics and COVID-19, as well as collaborative networks, the researcher utilized version 1.6.18 of the VOSviewer software. Scopus data were analysed to extract information on the types of publications, annual research output, countries, institutions, funding agencies, journals, citations, and highly cited references. Microsoft Excel 2019 was used to process and organize the extracted data.
    RESULTS: This study analysed 1137 documents related to COVID-19 and antibiotics and found that the number of publications increased from 130 in 2020 to 527 in 2022. These publications included 777 (68.34%) articles and 205 (18.03%) reviews. The top five countries in terms of scientific production were the United States (n = 231; 20.32%), the United Kingdom (n = 156; 13.72%), China (n = 101; 8.88%), India (n = 100; 8.8%), and Italy (n = 63; 5.54%), and the leading institutions were Imperial College London (n = 21; 1.85%), University of Oxford (n = 20; 1.76%), and University College London (n = 15; 1.32%). The National Natural Science Foundation of China provided funding for the highest number of articles (n = 48; 4.22%), followed by the National Institutes of Health (n = 32; 2.81%). The most productive journals were Antibiotics (n = 90; 7.92%), Journal of Antimicrobial Chemotherapy (n = 30; 2.64%), and Infection Control and Hospital Epidemiology (n = 26; 2.29%). Finally, the research hotspots identified in this study were 'antimicrobial stewardship during the COVID-19 outbreak' and 'implications of the COVID-19 pandemic on the emergence of antimicrobial resistance.'
    CONCLUSIONS: This is the first bibliometric analysis of COVID-19-related research on antibiotics. Research was carried out in response to global requests to increase the fight against AMR and awareness of the issue. More restrictions on the use of antibiotics are urgently needed from policy makers and authorities, more so than in the current situation.
    Keywords:  Antibiotic use; Antimicrobial resistance; Antimicrobial stewardship; COVID-19
    DOI:  https://doi.org/10.1186/s41043-023-00386-2
  50. Int J Surg. 2023 May 19.
       BACKGROUND: Surgical simulation training enables surgeons to acquire clinical experience or skills from the operating room to the simulation environment. Historically, it has changed with advances in science and technology. Moreover, no previous study has analyzed this field from the bibliometric analysis dimension. The study aimed to review changes in surgical simulation training worldwide using bibliometric software.
    MATERIALS AND METHODS: Two searches were performed on the core collection database, Web of Science (WOS), regarding data from 1991 to the end of 2020 using three topic words (surgery, training, and simulation). From January 1st, 2000, to May 15th, 2022, the keyword 'robotic' was added for the hotspot exploration. The data were chiefly analyzed by publication date, country, author(s), and keywords using bibliometric software.
    RESULTS: A total of 5,285 articles were initially analyzed, from which it was clear that laparoscopic skill, three-dimensional (3D) printing, and virtual reality (VR) were the main focuses during those study periods. Subsequently, 348 publications on robotic surgery training were identified.
    CONCLUSION: This study systematically summarizes the current status in the field of surgical simulation training and provides insights into the research focuses and future hotspot in a global context.
    DOI:  https://doi.org/10.1097/JS9.0000000000000468
  51. Asian J Surg. 2023 May 12. pii: S1015-9584(23)00703-0. [Epub ahead of print]
      
    Keywords:  Acute aortic dissection; Bibliometric analysis; Predictive model
    DOI:  https://doi.org/10.1016/j.asjsur.2023.05.024
  52. Asian J Surg. 2023 May 13. pii: S1015-9584(23)00652-8. [Epub ahead of print]
      
    Keywords:  Acute kidney injury; Bibliometric analysis; Cardiac surgery-associated
    DOI:  https://doi.org/10.1016/j.asjsur.2023.04.129
  53. Healthcare (Basel). 2023 Apr 27. pii: 1249. [Epub ahead of print]11(9):
      Unrestrained urbanisation and natural space loss are reducing contact with nature in today's society, producing negative consequences for people's mental and physical health and wellbeing. Nature-based therapies, such as physical activity in natural settings, forest bathing, therapeutic hiking, or experiential learning, reduce anxiety and depressive symptoms and improve the quality of life in both general and specific populations. A bibliometric analysis of research on nature-based therapies was performed by applying the traditional laws of bibliometrics (exponential growth law, Bradford's concentration law, Lotka's law, Zipf's law, etc.) to documents published in journals indexed in the Core Collection of the Web of Science (WoS). Graphical visualisation was performed using the VOSviewer software. Annual publications between 2006 and 2021 presented an exponential growth trend (R2 = 91%). The International Journal of Environmental Research and Public Health (MDPI) and Urban Forestry & Urban Greening (Elsevier) were the most productive and cited journals. Ikei, Miyazaki, and Song are the most cited prolific authors. The USA and South Korea were the countries with the highest scientific production. In recent years, there has been a growing interest in adventure, nature, and forest therapies among researchers. Nature-based therapies have experienced a growing interest in recent years. Positive effects on mental, physical, and emotional health have been found in different populations and research lines, although more studies with different designs and populations are needed.
    Keywords:  bibliometrics; green spaces; health; one health; wellbeing
    DOI:  https://doi.org/10.3390/healthcare11091249
  54. Int J Environ Res Public Health. 2023 04 24. pii: 5621. [Epub ahead of print]20(9):
      Virtual reality is an emerging field in mental health and has gained widespread acceptance due to its potential to treat various disorders, such as anxiety and depression. This paper presents a bibliometric analysis of virtual reality (VR) use in addressing depression and anxiety from 1995 to 2022. The study analysed 1872 documents using the Scopus database, identifying the field's most relevant journals and authors. The results indicate that using VR for addressing anxiety and depression is a multidisciplinary field with a wide variety of research topics, leading to significant collaborative research in this area. The Annual Review of Cybertherapy and Telemedicine was identified as the most relevant journal, while Behavior Research and Therapy was found to be the most cited journal. The analysis of keywords suggests that there is more research on using VR for anxiety and related disorders than for depression. Riva G. was identified as the top author in producing research outputs on VR-AD, and the University of Washington emerged as the leading institution in scientific outputs on VR-AD. Thematic and intellectual analyses helped identify the main themes within the research domain, providing valuable insight into the current and future directions of the field.
    Keywords:  anxiety; cognitive behavioural therapy; depression; exposure therapy; virtual reality
    DOI:  https://doi.org/10.3390/ijerph20095621
  55. Front Physiol. 2023 ;14 1042603
      Introduction: In recent years, more and more studies have proved that lipid metabolism plays an essential role in breast cancer's proliferation and metastasisand also has a specific significance in predicting survival. Methods: This paper collected data from 725 publications related to lipid metabolism in breast neoplasm from 2012 to 2021 through the Web of Science Core Collection database. Bibliometrix, VOSviewer, and CiteSpace were used for the scientometrics analysis of countries, institutions, journals, authors, keywords, etc. Results: The number of documents published showed an increasing trend, with an average annual growth rate of 14.49%. The United States was the most productive country (n = 223, 30.76%). The journals with the largest number of publications are mostly from developed countries. Except for the retrieved topics, "lipid metabolism" (n = 272) and "breast cancer" (n = 175), the keywords that appeared most frequently were "expression" (n = 151), "fatty-acid synthase" (n = 78), "growth" (n = 72), "metabolism" (n = 67) and "cells" (n = 66). Discussion: These findings and summaries help reveal the current research status and clarify the hot spots in this field.
    Keywords:  CiteSpace; VOSviewer; bibliometrix; breast neoplasm; lipid metabolism; scientometrics
    DOI:  https://doi.org/10.3389/fphys.2023.1042603
  56. Environ Sci Pollut Res Int. 2023 May 19.
      Bioretention is a typical low impact development (LID) practice that helps reduce peak urban stormwater runoff and runoff pollutant concentrations (e.g., heavy metals, suspended solids, organic pollutants), which has become an important part of urban stormwater management over the past 15 years. To understand the research hotspots and frontiers in the field of bioretention facility research and provide a reference for research into bioretention facilities, we conduct a statistical analysis of global bioretention literature published during 2007-2021 using the Web of Science core database and the data visualization and analysis software VOSviewer and HistCite. The number of published articles related to bioretention facilities shows a rising trend over the study period, with research from China contributing greatly to global research on bioretention facilities. However, the influence of articles needs to be increased. Recent studies mainly focus on the hydrologic effect and water purification effect of bioretention facilities and on the removal of nitrogen and phosphorus nutrients from runoff rainwater. Further studies should focus on the interaction of fillers, microorganisms, and plants in bioretention facilities and its impact on the migration, transformation, and concentrations of nitrogen and phosphorus; the purification effect and mechanism of specific emerging contaminants in runoff; the selection and configuration optimization of filler materials and plant species; and the optimization of the design parameters of the model for bioretention systems.
    Keywords:  Bibliometrics; Bioretention; Runoff; Web of Science
    DOI:  https://doi.org/10.1007/s11356-023-27616-8
  57. Front Surg. 2023 ;10 1120442
       Purpose: In this study, the aim was to comprehensively analyze the current status, hotspots, and trends of trans-oral endoscopic thyroidectomy (TOET) through bibliometric analysis and by presenting the field atlas.
    Methods: Web of Science Core Collection database was adopted to screen studies regarding TOET published between January 1, 2008 and August 1, 2022. The evaluation covered the criteria total number of studies, keywords, and contributions from countries/regions, institutions, journals, and authors.
    Results: A total of 229 studies were covered. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES is the largest publication in the field of TOET. The three countries that contributed the most studies were Korea, China, and the USA. The most frequently occurring core keywords in the field of TOET are vestibular approach, outcomes, experience, safety, robotic thyroidectomy, scar, video-assisted thyroidectomy and quality-of-life. The seven clusters were generated in this study: intraoperative monitoring of the laryngeal return nerve (# 0), learning curve (# 1), postoperative quality of life (# 2), central lymph node dissection and safety (# 3), complications (# 4), minimally invasive surgery (# 5), and robotic surgery (# 6).
    Conclusion: The main research topics in the field of TOET place focuses on learning curves, laryngeal nerve monitoring, carbon dioxide gas bolus, chin nerve injury, surgical complications, and surgical safety. In the future, more academics will focus on the safety of the procedure and reducing complications..
    Keywords:  TOET; bibliometrics; research trends; thyroidectomy; transoral; vestibular approach
    DOI:  https://doi.org/10.3389/fsurg.2023.1120442
  58. Surg Endosc. 2023 May 19.
       BACKGROUND: Research presentation has benefits, including CV building, networking, and collaboration. A measurable standard for achievement is publication in a peer-reviewed journal. Expectations regarding the likelihood of publication are unknown for studies presented at a national surgical scientific meeting. This study aims to evaluate predictors of manuscript publication arising from abstracts presented at a national surgical scientific meeting.
    METHODS: Abstracts presented at the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Meeting 2019 were reviewed. Identification of published manuscripts was completed using MedLine, Embase, and Google Scholar 28 months after the presentation to allow for time for publication. Factors evaluated for association with publication included author and abstract measures. Descriptive analyses and multivariable statistics were performed.
    RESULTS: 724 abstracts (160 podiums, 564 posters) were included. Of the podium presentations, 128 (80%) were published in a median of 4 months after the presentation. On univariable and multivariable analyses, there was no association between publication and abstract topic, gender, degree, number of publications, or H-indices of first and senior authors. 154 (27.3%) poster presentations were published with a median of 13 months. On univariable analysis, there was a statistically significant difference regarding the abstract topic (p = 0.015) and senior author degree (p = 0.01) between published and unpublished posters. Multivariable analysis demonstrated that colorectal surgery (OR 2.52; CI 1.02-6.23) and metabolic/obesity (OR 2.53; CI 1.09-5.84) are associated with an increased odd of publication. There was an inverse association with female senior authors (OR 0.53; CI 0.29-0.98), while additional degrees (e.g., doctorate and/or master's degree) of the senior authors were associated with an increased publication rate (OR 1.80; CI 1.00-3.22).
    CONCLUSION: 80% of podiums but only 27% of posters were ultimately published. While some predictors of poster publication were noted, it is unclear if these are why these projects fail to publish. Future research is warranted to determine if there are effective strategies to increase poster publication rates.
    Keywords:  Abstract; Conference; National meeting; Podium presentation; Poster presentation; Publication rate
    DOI:  https://doi.org/10.1007/s00464-023-10139-1
  59. Front Pharmacol. 2023 ;14 1105459
      Introduction: The new coronavirus has caused a pandemic that has infected hundreds of millions of people around the world since its outbreak. But the cardiovascular damage caused by the new coronavirus is unknown. We have analyzed the current global scenario and the general pattern of growth. After summarizing the known relationship between cardiovascular diseases and new coronary pneumonia, relevant articles are analyzed through bibliometrics and visualization. Methods: Following our pre-designed search strategy, we selected publications on COVID-19 and cardiovascular disease in the Web of Science database. In our relevant bibliometric visualization analysis, a total of 7,028 related articles in the WOS core database up to 20th October 2022 were summarized, and the most prolific authors, the most prolific countries, and the journals and institutions that published the most articles were summarized and quantitatively analyzed. Results: SARS-CoV-2 is more infectious than SARS-CoV-1 and has significant involvement in the cardiovascular system in addition to pulmonary manifestations, with a difference of 10.16% (20.26%/10.10%) in the incidence of cardiovascular diseases. The number of cases increases in winter and decreases slightly in summer with temperature changes, but the increase in cases tends to break out of seasonality across the region as mutant strains emerge. The co-occurrence analysis found that with the progress of the epidemic, the research keywords gradually shifted from ACE2 and inflammation to the treatment of myocarditis and complications, indicating that the research on the new crown epidemic has entered the stage of prevention and treatment of complications. Conclusion: When combined with the current global pandemic trend, how to improve prognosis and reduce human body damage could become a research focus. At the same time, timely detection, prevention, and discovery of new mutant strains have also become key tasks in the fight against the epidemic, and full preparations have been made to prevent the spread of the next wave of mutant strains, and still need to continue to pay attention to the differential performance of the variant "omicron."
    Keywords:  ACE2; SARS-CoV-2; bibliometrics; cardiovascular disease; omicron
    DOI:  https://doi.org/10.3389/fphar.2023.1105459
  60. Polymers (Basel). 2023 Apr 26. pii: 2057. [Epub ahead of print]15(9):
      Lignocellulosic biomasses are used in several applications, such as energy production, materials, and biofuels. These applications result in increased consumption and waste generation of these materials. However, alternative uses are being developed to solve the problem of waste generated in the industry. Thus, research is carried out to ensure the use of these biomasses as enzymatic support. These surveys can be accompanied using the advanced bibliometric analysis tool that can help determine the biomasses used and other perspectives on the subject. With this, the present work aims to carry out an advanced bibliometric analysis approaching the main studies related to the use of lignocellulosic biomass as an enzymatic support. This study will be carried out by highlighting the main countries/regions that carry out productions, research areas that involve the theme, and future trends in these areas. It was observed that there is a cooperation between China, USA, and India, where China holds 28.07% of publications in this area, being the country with the greatest impact in the area. Finally, it is possible to define that the use of these new supports is a trend in the field of biotechnology.
    Keywords:  bibliometric analysis; enzymatic immobilization; lignocellulosic biomass
    DOI:  https://doi.org/10.3390/polym15092057
  61. Mol Cell Biochem. 2023 May 13.
      Saliva has emerged as a promising noninvasive biofluid for the diagnosis of oral and systemic diseases, including viral infections. During the coronavirus disease 2019 (COVID-19) pandemic, a growing number of studies focused on saliva-based detection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Taking advantage of the WoS core collection (WoSCC) and CiteSpace, we retrieved 1021 articles related to saliva-based detection of SARS-CoV-2 and conducted a comprehensive bibliometric analysis. We analyzed countries, institutions, authors, cited authors, and cited journals to summarize their contribution and influence and analyzed keywords to explore research hotspots and trends. From 2020 to 2021, research focused on viral transmission via saliva and verification of saliva as a reliable specimen, whereas from 2021 to the present, the focus of research has switched to saliva-based biosensors for SARS-CoV-2 detection. By far, saliva has been verified as a reliable specimen for SARS-CoV-2 detection, although a standardized procedure for saliva sampling and processing is needed. Studies on saliva-based detection of SARS-CoV-2 will promote the development of saliva-based diagnostics and biosensors for viral detection. Collectively, our findings could provide valuable information to help scientists perceive the basic knowledge landscapes on saliva-based detection of SARS-CoV-2, the past and current research hotspots, and future opportunities.
    Keywords:  Bibliometric analysis; COVID-19; CiteSpace; Detection; SARS-CoV-2; Saliva
    DOI:  https://doi.org/10.1007/s11010-023-04760-w
  62. Healthcare (Basel). 2023 Apr 27. pii: 1248. [Epub ahead of print]11(9):
      Despite the increasing awareness of long-term care (LTC) research after the outbreak of COVID-19 pandemic, little attention was given to quantitatively describe the evolution of the research field during this period. A total of 1024 articles retrieved from the Web of Science Core Collection database were systematically analyzed using CiteSpace visualization software. The overall characteristics analysis showed that, in the context of the pandemic, attention to LTC research increased significantly-over 800 articles were published in the past two years. The USA, Canada, Italy, and England formed the leading LTC research group, which was consistent with the conclusions of existing bibliometric studies on LTC research before the outbreak. A rigorous analysis based on a dual perspective of references and keywords was applied to reveal that, compared with previous studies, in the context of the pandemic, the focus shifted from the mental and physical health status of older adults in need of LTC to the impact of the pandemic on those of older adults in LTC facilities, from the prevention of general epidemics to the prevention and response of significant public health emergencies, from providing and paying for LTC to strategies for LTC facilities to improve the quality of LTC and well-being of their residents during the pandemic. These findings can provide help and reference for academics, civil folks, and LTC practitioners, as well as help with the sustainable development of LTC research in the context of COVID-19 pandemic.
    Keywords:  COVID-19 pandemic; CiteSpace; long-term care; visualization
    DOI:  https://doi.org/10.3390/healthcare11091248
  63. Environ Sci Pollut Res Int. 2023 May 18.
      In the context of global carbon neutrality, climate change mitigation and response has become a top priority. Currently, countries around the world are setting emission reduction targets or are already involved in carbon-neutral actions, with technological innovation becoming the key to global emission reduction. Therefore, a systematic review of the literature related to technology innovation and emission reduction in response to carbon-neutral actions for climate change is conducted. A global bibliometric visualization analysis is presented using CiteSpace and VOSviewer software. This study visualizes the basic relationship between global emission reduction and technology-related literature under the carbon neutrality target and analyzes and discusses the spatial distribution and hotspot trends of the co-author network and knowledge base. The results show that (1) the trend of the number of relevant studies can be divided into two phases before and after, and starts to increase gradually after 2020. (2) The structural relationship of the author- and institution-based cooperative networks is relatively loose, and the main cooperative networks, mainly by countries, are initially formed by the key contributions of developed and emerging economies. (3) Relevant research hotspots are reflected in multiple perspectives such as investment, management, and policy, in addition to emission reduction targets and technological innovation itself. The causal relationship between relevant research and economic and political dimensions has become an important driving factor for research development. Especially in the paradigm shift phase, there are research characteristics of human intervention and specific actions. (4) In terms of future trends, research involving policy management, methodological efficiency, and systemic models will become important research paths in the future by matching the supply of actions to real needs.
    Keywords:  Bibliometrics; Carbon neutrality; Global emission reduction; Technological innovation
    DOI:  https://doi.org/10.1007/s11356-023-27684-w
  64. Behav Anal Pract. 2023 Jun;16(2): 617-622
      Researchers have recently had greater interest in publishing data on women's participation in behavior analysis. This emphasis has resulted in analyses of women's representation as authors of peer-reviewed publications, and the results have been largely encouraging. Another area to study in this line of research is serving as a keynote or invited speaker at conferences. Although there are some limited data published in this area, no study has yet examined women's participation in these roles across all U.S. state associations for behavior analysis. Thus, we analyzed all U.S. state association keynote and invited conference speakers from 2015 to 2020.
    Keywords:  bias; dissemination; keynote speakers; presentations; women and men
    DOI:  https://doi.org/10.1007/s40617-022-00755-z
  65. Eval Rev. 2023 May 17. 193841X231176869
      The impact of pro-environmental behavior on policymaking has been an exciting area of research. While the relationship between pro-environmental behavior and policymaking has been explored in numerous studies, there needs to be more synthesis on this topic. This is the first text-mining study of pro-environmental effects in which policymaking is a significant factor. In response, this study, for the first time, takes a novel approach by using text mining in R programming to analyze 30 publications from the Scopus database on pro-environmental behavior in policymaking, highlighting major research themes and prospective research areas for future investigation. Results from text mining yielded 10 topic models, which are presented with a synopsis of the published research and a list of the primary authors, as well as a posterior probability via latent Dirichlet allocation (LDA). Additionally, the study conducts a trend analysis of the top 10 journals with the highest impact factor, considering the influence of each journal's mean citation. The study offers an overview of the impacts of pro-environmental behavior in policymaking, showing the most relevant and frequently discussed themes, introduces the scientific visualization of papers published in the Scopus database, and proposes future study directions. These findings can help researchers and environmental specialists better understand how pro-environmental behavior can be fostered more effectively through policymaking.
    Keywords:  management; policymaking; pro-environmental behavior; review; text mining
    DOI:  https://doi.org/10.1177/0193841X231176869
  66. Behav Anal Pract. 2023 Jun;16(2): 399-406
      When Behavior Analysis in Practice (BAP) was founded 15 years ago, questions were raised about whether a practitioner-focused journal was really needed to complement our field's well-established applied research periodicals. Like research journals, BAP publishes primary research reports for which scholarly citations are one measure of impact. Unlike most research journals, it also was intended to achieve dissemination impact, which implies influence on people who may not conduct research or leave behind citations. Using altmetric data as an objective measure of dissemination impact, we present evidence that BAP is becoming a leader in this domain among applied behavior analysis journals, and thus appears to be accomplishing exactly what it was designed to. We recommend explicitly relying on dissemination impact data to help shape the journal's future development.
    Keywords:  Altmetrics; Applied behavior analysis; Bibliometrics; Dissemination
    DOI:  https://doi.org/10.1007/s40617-022-00744-2
  67. Eur J Investig Health Psychol Educ. 2023 Apr 06. 13(4): 748-758
      The smartphone has become integral to most aspects of students' lives and is the primary conduit for accessing the internet. Objective research into the promise and dangers of this device is critical. While educational uses of the smartphone with young adults hold promise, the potential for harm is also present. While objectivity is valued, the focus of researchers can subjectively skew towards optimistic or pessimistic views of technology. The topics addressed in smartphone and learning research illuminate trends and potential biases in the field. This study investigates the issues addressed in smartphone and learning research in the past two years. These topics are compared with smartphone research in a similar field: psychology. The study, using a bibliometric approach, identified an overall negative arc of the literature towards topics such as addiction, depression, and anxiety in the psychology literature. The educational literature topics were comparatively more positive than psychology. Highly cited papers in both fields reflected explorations of adverse outcomes.
    Keywords:  M-learning; bibliometrics; smartphone; smartphones and learning
    DOI:  https://doi.org/10.3390/ejihpe13040056
  68. J Clin Epidemiol. 2023 May 16. pii: S0895-4356(23)00105-1. [Epub ahead of print]
       BACKGROUND: There is an increasing number of qualitative systematic reviews being produced. Searching for qualitative literature to include in these systematic reviews is, however, more challenging and may result in less than favorable recall. Database searches relying solely on key elements of the research question may not retrieve all relevant qualitative studies for synthesis, and supplementary searches may be pertinent to complement the searches. This study aimed to determine, if a) supplementary search strategies (citation searches and alternative search strategies) were able to identify relevant publications for qualitative systematic reviews that were non-retrievable, when conducting traditional database searches based on key elements; and b) to investigate the total number of identified publications when combining traditional database searches with these supplementary search strategies.
    METHODS: From a previous study, a gold standard of 12 qualitative reviews including 101 PubMed-indexed publications were used. One of the reviews had only one included publication and in one review, the two included studies were identifiable in PubMed. In the remaining 10 reviews, 61 publications were retrievable through traditional database searches, and 37 were non-identifiable. The 61 publications were used as basis for possible identification of the 37 publications by using the supplementary search strategies: citations searches (review of reference lists, PubMed "Cited by" function; Scopus "Cited by" function, Citationchaser, CoCites plugin for PubMed) and alternative search strategies (PubMed "similar articles" function; Scopus "Related documents based on references"), RESULTS: Traditional database searches retrieved 62.4% of the 101 publications. Citations searches in Scopus, Citationchaser and CoCites identified 21 (56.8%) of the 37 remaining publications. The PubMed "Cited by" function did not identify any of the 37 publications. The alternative search strategies, the PubMed "Similar articles" together with Scopus "Related documents based on references"-function) identified 15 (40.5%) of the 37 publications. Together, these supplementary search strategies identified 25 (67.6%) of the 37 publications, resulting in an overall retrieval of 87.1%, when combining traditional database searches and supplementary search strategies.
    CONCLUSION: The results of this study indicate that supplementary search strategies (citation searches and alternative search strategies) increase the retrieval potential, when searching for qualitative publications and should be included, when identifying literature for qualitative reviews.
    DOI:  https://doi.org/10.1016/j.jclinepi.2023.04.017
  69. Obes Res Clin Pract. 2023 May 13. pii: S1871-403X(23)00041-8. [Epub ahead of print]
      Obesity is a global pandemic with increasing prevalence and long-term negative health outcomes. Bariatric metabolic surgery (BMS) is the most effective treatment option for achieving long-term weight loss. A systematic search was performed from 1990 to 2020 of BMS procedures using standardised groups. Data were collected on operation type reported, country and continent of publication. North America and Europe were the leading contributors to global publications in BMS, producing 41.3 % (n = 4931) and 37.1 % (n = 4436) of publications respectively, with increasing publications from Asia. Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) were the most studied procedure types with number of publications continuing to increase over time. A plateau and downward trend was seen for Laparoscopic Adjustable Gastric Band (LAGB) publication from 2015 to 2019. An increase in emerging/experimental techniques over the past decade is observed.
    Keywords:  Bariatric surgery; Bibliometric; Global trends; Metabolic surgery; Obesity
    DOI:  https://doi.org/10.1016/j.orcp.2023.05.003
  70. J Womens Health (Larchmt). 2023 May 18.
      Objective: The gendered impact of the COVID-19 on scientific productivity has been primarily studied in nonclinical academic fields. We investigated the gendered effect of the pandemic on diverse measures of research participation among physician faculty, who experienced an increase in clinical duties concomitant with pandemic-era challenges to research. Materials and Methods: Physician faculty employed in both 2019 (prepandemic) and 2021 (pandemic era) were identified at one U.S. medical school. Annual outcomes included scientific publications, Institutional Review Board (IRB)-approved protocols, and extramural funding submissions (funding data were unavailable for 2019). Mixed-effects Poisson regression models compared the pandemic impact by gender. Results: The study included 105 women and 116 men, contributing to 122 publications, 214 IRB protocols, and 99 extramural funding applications. Controlling for potential confounders such as faculty rank and track (tenure vs. nontenure), women's publication count increased by 140% during the pandemic (95% confidence interval [CI]: +40% to +310%, p = 0.001) but was unchanged among men (95% CI: -30% to +50%; p > 0.999). The number of IRB protocols decreased from 2019 to 2021, but to a greater extent among men than women. In 2021, there was no gender difference in the number of extramural funding submissions. Conclusions: Among physician faculty at our medical school, women achieved parity with men on multiple measures of scholarly activity, and women's research productivity outpaced that of men in the same faculty track and rank. Targeted initiatives to support research among women faculty, junior investigators, and clinical investigators may have helped avert exacerbation of prepandemic gender disparities in research participation.
    Keywords:  COVID-19; academic medicine; gender; scholarly productivity; women
    DOI:  https://doi.org/10.1089/jwh.2022.0390
  71. Plast Reconstr Surg Glob Open. 2023 May;11(5): e4996
      This study aimed to analyze the association between completion of research training and career success in American plastic surgery faculty to aid trainees in their decisions to perform research fellowships.
    Methods: A cross-sectional analysis of attending academic plastic surgeons in the United States was conducted. Outcomes were compared between faculty who completed research training (research fellowship, PhD, or MPH) and those who did not. Outcomes included promotion to full professor and/or department chair, h-index, and attainment of National Institutes of Health funding. Outcomes were analyzed using chi-squared tests, t tests, and multivariable regressions.
    Results: A total of 949 plastic surgery faculty members were included, and of those, 185 (19.5%) completed dedicated research training, including 13.7% (n = 130) who completed a research fellowship. Surgeons who completed dedicated research training were significantly more likely to achieve full professorship (31.4% versus 24.1%, P = 0.01), obtain National Institutes of Health funding (18.4% versus 6.5%, P < 0.001), and have a higher mean h-index (15.6 versus 11.6, P < 0.001). Dedicated research fellowships were independently predictive of achieving full professorship (OR = 2.12, P = 0.002), increased h-index (β = 4.86, P < 0.001), and attainment of National Institutes of Health funding (OR = 5.06, P = 0.01). Completion of dedicated research training did not predict an increased likelihood of becoming department chair.
    Conclusion: The performance of dedicated research training was predictive of improved markers of career success in plastic surgery and should be considered beneficial in both the short and long term.
    DOI:  https://doi.org/10.1097/GOX.0000000000004996
  72. BMJ. 2023 May 17. 381 e074968
       OBJECTIVE: To determine whether gender and racial inequities exist among Lasker Award recipients.
    DESIGN: Observational, cross sectional analysis.
    SETTING: Population based study.
    PARTICIPANTS: Recipients of four Lasker Awards from 1946 to 2022.
    MAIN OUTCOME MEASURES: Gender and race (non-white categorized as racialized v white categorized as non-racialized) of all Lasker Award recipients. Personal characteristics of award recipients were categorized by four independent authors using previously established methods and consistency of categorization among authors was analyzed. Women and non-white people were thought to be underrepresented among Lasker Award recipients compared with professional degree recipients overall.
    RESULTS: Among 397 Lasker Award recipients since 1946, 92.2% (366/397) were men. Most award recipients were identified as white (95.7%, 380/397). One non-white woman was identified as having received a Lasker Award over the course of seven decades. The proportion of women among award recipients in the most recent decade (2013-22) is similar to the first decade of awards (1946-55; 15.6%, 7/45 v 12.9%, 8/62). The median timeframe from terminal degree receipt to Lasker Award conferral for all award recipients is 30 years. The proportion of women who received a Lasker Award between 2019 and 2022 (7.1%) was less than would be expected based on the proportion of life science doctorates awarded to womenin 1989 (30 years previously; 38.1%).
    CONCLUSIONS: The number of women and non-white people in academic medicine and biomedical research continues to increase, yet the proportion of women among Lasker Award recipients has not changed in more than 70 years. Additionally, time from terminal degree receipt to Lasker Award conferral does not appear to fully account for the observed inequities. These findings establish the need for further investigation of possible factors that could hinder women and non-white people from entering the pool of eligible award recipients, potentially limiting the diversification of the science and academic biomedical workforce.
    DOI:  https://doi.org/10.1136/bmj-2023-074968
  73. Heliyon. 2023 May;9(5): e16075
      Rare earth refers to a type of strategic resource. Countries worldwide have invested considerable money in relevant research. This bibliometric study was to evaluate the global situation of published rare earth research to discover rare earth research strategies in a wide range of countries. In this study, 50,149 SCI papers related to rare earth were collected. In addition, we divided the above papers into 11 main research fields according to discipline and keyword clustering, and divided the above theoretical cultures into different industry fields according to the keywords of the above papers. After that, the research directions, research institutions, funding, and other aspects of rare earth research in numerous countries were compared. The result of this study suggests that China's rare earth research has been generally in the leading position worldwide, whereas there are still some problems in the discipline layout, strategic strategies, green development, and fund support. Other countries place a greater focus on areas regarding national security strategies (e.g., mineral exploration, smelting, and permanent magnetism).
    Keywords:  Bibliometrics; Development trend; International comparison; Policy recommendation; Rare earth
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e16075
  74. J Clin Med. 2023 Apr 27. pii: 3152. [Epub ahead of print]12(9):
       PURPOSE: Andrological diseases have an important social and economic impact as they cause a serious impairment of the quality of life of the affected patient. Epidemiologically, the impact of these disorders is progressively increasing, as demonstrated by the ever-growing prevalence of male infertility. This evidence justifies the rapid development of research in andrology that the scientific community has undertaken in recent decades. This study aims to evaluate the productivity index of the main andrological topics studied and reported in the literature.
    METHODS: The total number of published articles was extracted from the Scopus database by entering the following keywords and mesh terms: "Male Infertility", "Erectile Dysfunction", "Premature Ejaculation", "Male Hypogonadism", "Testicular Tumors", "Prostate Cancer", "Prostatic hyperplasia", "Prostate hyperplasia", "Prostatitis", "Prostate inflammation", and "Male Accessory Gland Infections". Furthermore, a list of the top 50 researchers sorted by productivity was created for each topic. For male infertility, a further search was performed by combining the search term "male infertility" with the above-mentioned terms. Thus, a list of the top 30 authors in order of productivity was also extracted. The graphs were created using Excel.
    RESULTS AND CONCLUSIONS: As could be expected, we observed that prostate cancer and male infertility were the two most investigated topics, followed by benign prostatic hyperplasia and erectile dysfunction, whose prevalence is set to increase given the progressive aging of the population. Less investigated is the inflammation of the accessory sexual glands. In conclusion, this study provides a ranking of the main andrological topics investigated in the literature, also presenting the top list of the most productive authors for each one.
    Keywords:  andrological field; andrology; male infertility; productivity index; top scientist
    DOI:  https://doi.org/10.3390/jcm12093152
  75. Int J Environ Res Public Health. 2023 04 27. pii: 5657. [Epub ahead of print]20(9):
      The Japanese term hikikomori was first used to describe prolonged social withdrawal in the 1990s. Since then, research across the world have reported similar prolonged social withdrawal in many countries outside Japan. This study systematically analyses the evolution of literature on hikikomori in the past 20 years to gain a better understanding of the development of the knowledge base on hikikomori since it garnered attention in Japan. Findings from the scientometric review indicate many perspectives on the etiology of hikikomori including cultural, attachment, family systems and sociological approaches. However, similarities with modern type depression, a novel psychiatric syndrome, have been proposed and there are signs of a recent paradigm shift of hikikomori as a society-bound syndrome rather than a cultural-bound syndrome unique to Japan. As research into hikikomori continues to grow, results from the review also highlight the need for a more universally shared definition of hikikomori in order to better consolidate cross-cultural research for meaningful and valid cross-cultural comparisons which can help to promote evidence-based therapeutic interventions for hikikomori.
    Keywords:  country analysis; document co-citation analysis; hikikomori; scientometrics; social withdrawal
    DOI:  https://doi.org/10.3390/ijerph20095657
  76. Can J Anaesth. 2023 May 15.
       PURPOSE: We aimed to evaluate the representation of women and persons of colour (POC) authors of COVID-19 manuscripts submitted to, accepted in, and rejected from the Journal and to evaluate trends in their representation during the pandemic.
    METHODS: All COVID-19 manuscripts submitted to the Journal between 1 February 2020 and 30 April 2021 were included. Manuscript data were retrieved from Editorial Manager, and gender and POC status were obtained through: 1) e-mail communication with corresponding authors; 2) e-mail queries to other coauthors; 3) NamSor software, and 4) Internet searches. The data were described using percentages and summary statistics. A two-sample test of proportions was used for comparisons and trends were analyzed with linear regression.
    RESULTS: We identified 314 manuscripts (1,555 authors), 95 (461 authors) of which were accepted for publication. Of all authors, 515 (33%) were women, and women were the lead and senior authors of 101 (32%) and 69 (23%) manuscripts, respectively. There were no differences in women's representation as authors between accepted and rejected manuscripts. Overall, 923/1,555 (59%) authors were identified as POC, with a significantly lower proportion of POC authors among accepted vs rejected manuscripts (41%, 188/461 vs 67%, 735/1,094; difference, -26%; 95% CI, -32 to -21; P < 0.001). We did not observe significant trends in the proportion of women and POC authors over the study period.
    CONCLUSION: The proportion of women authors of COVID-19 manuscripts was lower than men's representation. Further research is required to determine the factors that account for the higher proportion of POC authors across rejected manuscripts.
    Keywords:  COVID-19; equity; gender; person of colour; productivity
    DOI:  https://doi.org/10.1007/s12630-023-02455-w
  77. Front Pediatr. 2023 ;11 1185329
       Introduction: Women are under-represented in virtually all fields of academic medicine. Even in pediatrics, a field that historically attracts a workforce with a majority of women physicians, substantial gender disparities persist in leadership positions. However, previous studies of gender representation in various academic settings are limited to small studies or aggregate pediatric subspecialties, thereby omitting important granularity within each subspecialty. No prior studies have investigated potential gender disparities in pediatric nephrology. The aim of this study is to determine the representation of women physicians in leadership and speaking roles in the annual American Society of Pediatric Nephrology (ASPN) meeting.
    Methods: Data were analyzed from the 2012-2022 ASPN annual scientific meetings at the Pediatric Academic Society (PAS). Data were abstracted regarding gender and roles: speaker, chair/moderator, and lifetime achievement awardee. We performed a time series analysis using linear regression, with the year as the independent variable and the proportion of women as the dependent variable.
    Results: Overall, there were statistically significant increases in the proportion of women speakers per year and percentage of women chairs or moderators. There were no specific trends noted for lifetime achievement awards and no statistically significant changes in the number of lifetime achievement awards.
    Discussion: We found proportionate representations of gender representation with regards to speakers and chairs or moderators, although our data was limited by comparison to the American Board of Pediatrics (ABP) workforce cumulative "ever certified" data. The ABP data include a disproportionate representation of faculty who are men from earlier certification periods who may no longer be actively practicing pediatric nephrology.
    Keywords:  diversity; equity; pediatric nephrology; pediatrics; presentation of women; representation; trends
    DOI:  https://doi.org/10.3389/fped.2023.1185329
  78. JAMA Surg. 2023 May 17.
       Importance: Surgeon-scientists are uniquely positioned to facilitate translation between the laboratory and clinical settings to drive innovation in patient care. However, surgeon-scientists face many challenges in pursuing research, such as increasing clinical demands that affect their competitiveness to apply for National Institutes of Health (NIH) funding compared with other scientists.
    Objective: To examine how NIH funding has been awarded to surgeon-scientists over time.
    Design, Setting, and Participants: This cross-sectional study used publicly available data from the NIH RePORTER (Research Portfolio Online Reporting Tools Expenditures and Results) database for research project grants awarded to departments of surgery between 1995 and 2020. Surgeon-scientists were defined as NIH-funded faculty holding an MD or MD-PhD degree with board certification in surgery; PhD scientists were NIH-funded faculty holding a PhD degree. Statistical analysis was performed from April 1 to August 31, 2022.
    Main Outcome: National Institutes of Health funding to surgeon-scientists compared with PhD scientists, as well as NIH funding to surgeon-scientists across surgical subspecialties.
    Results: Between 1995 and 2020, the number of NIH-funded investigators in surgical departments increased 1.9-fold from 968 to 1874 investigators, corresponding to a 4.0-fold increase in total funding (1995, $214 million; 2020, $861 million). Although the total amount of NIH funding to both surgeon-scientists and PhD scientists increased, the funding gap between surgeon-scientists and PhD scientists increased 2.8-fold from a $73 million difference in 1995 to a $208 million difference in 2020, favoring PhD scientists. National Institutes of Health funding to female surgeon-scientists increased significantly at a rate of 0.53% (95% CI, 0.48%-0.57%) per year from 4.8% of grants awarded to female surgeon-scientists in 1995 to 18.8% in 2020 (P < .001). However, substantial disparity remained, with female surgeon-scientists receiving less than 20% of NIH grants and funding dollars in 2020. In addition, although there was increased NIH funding to neurosurgeons and otolaryngologists, funding to urologists decreased significantly from 14.9% of all grants in 1995 to 7.5% in 2020 (annual percent change, -0.39% [95% CI, -0.47% to -0.30%]; P < .001). Despite surgical diseases making up 30% of the global disease burden, representation of surgeon-scientists among NIH investigators remains less than 2%.
    Conclusion and Relevance: This study suggests that research performed by surgeon-scientists continues to be underrepresented in the NIH funding portfolio, highlighting a fundamental need to support and fund more surgeon-scientists.
    DOI:  https://doi.org/10.1001/jamasurg.2023.1571
  79. Infect Dis Poverty. 2023 May 16. 12(1): 51
       BACKGROUND: Climate change presents an imminent threat to almost all biological systems across the globe. In recent years there have been a series of studies showing how changes in climate can impact infectious disease transmission. Many of these publications focus on simulations based on in silico data, shadowing empirical research based on field and laboratory data. A synthesis work of empirical climate change and infectious disease research is still lacking.
    METHODS: We conducted a systemic review of research from 2015 to 2020 period on climate change and infectious diseases to identify major trends and current gaps of research. Literature was sourced from Web of Science and PubMed literary repositories using a key word search, and was reviewed using a delineated inclusion criteria by a team of reviewers.
    RESULTS: Our review revealed that both taxonomic and geographic biases are present in climate and infectious disease research, specifically with regard to types of disease transmission and localities studied. Empirical investigations on vector-borne diseases associated with mosquitoes comprised the majority of research on the climate change and infectious disease literature. Furthermore, demographic trends in the institutions and individuals published revealed research bias towards research conducted across temperate, high-income countries. We also identified key trends in funding sources for most resent literature and a discrepancy in the gender identities of publishing authors which may reflect current systemic inequities in the scientific field.
    CONCLUSIONS: Future research lines on climate change and infectious diseases should considered diseases of direct transmission (non-vector-borne) and more research effort in the tropics. Inclusion of local research in low- and middle-income countries was generally neglected. Research on climate change and infectious disease has failed to be socially inclusive, geographically balanced, and broad in terms of the disease systems studied, limiting our capacities to better understand the actual effects of climate change on health.
    Keywords:  Climate change; Infectious disease; Research trend; Systematic review
    DOI:  https://doi.org/10.1186/s40249-023-01102-2
  80. ANZ J Surg. 2023 Apr 26.
       BACKGROUND: The importance of gender diversity is well recognized. Despite promising change in addressing gender disparity, there remains a significant gap in women's representation in urology. Worldwide, a lack of diversity has been observed at scientific meetings. This study analyses the trend in women's representation at the Urological Society of Australia and New Zealand Annual Scientific Meeting (USANZ ASM) over the last nine years.
    METHOD: We retrospectively collected data from eight conference programs between 2014 and 2022, evaluating the trend in the proportion of women represented in various sections. A difference of proportions test was performed to determine whether a significant change was seen from year to year.
    RESULTS: A significant increase in women's representation was observed, the most significant increase was evident in the last three years, chairpersons increased from 5.9% to 44.1% (P = 0.003), international speakers from 11.7% to 39.1% (P ≤ 0.001), expert speakers from 19.1% to 42.0% (P = 0.002), and total speakers from 19.5% to 34.7% (P ≤ 0.001).
    CONCLUSION: Our study shows that a significant increase in the representation of women at the USANZ ASM has been achieved over the last three years. Unfortunately, this increase in representation has not been mirrored in the number of women trainees and training applicants. Additionally, this increase in representation well exceeds the proportion of women who are USANZ members, and is unevenly distributed across topics. A positive change has been observed, the challenge remains in dealing with unconscious bias and balancing the fine line between inclusivity and tokenism.
    Keywords:  conference; diversity; female; gender
    DOI:  https://doi.org/10.1111/ans.18497
  81. Drugs. 2023 May 18.
       BACKGROUND: Although expanded access is an increasingly used pathway for patients to access investigational medicine, little is known on the magnitude and content of published scientific research collected via expanded access.
    METHODS: We performed a review of all peer-reviewed expanded access publications between January 1, 2000 and January 1, 2022. We analyzed the publications for drugs, diseases, disease area, patient numbers, time, geographical location, subject, and research methodology (single center/multicenter, international/national, prospective/retrospective). We additionally analyzed endpoints reported in all COVID-19-related expanded access publications.
    RESULTS: We screened 3810 articles and included 1231, describing 523 drugs for 354 diseases for 507,481 patients. The number of publications significantly increased over time ([Formula: see text]). Large geographical disparities existed as Europe and the Americas accounted for 87.4% of all publications, whereas Africa only accounted for 0.6%. Oncology and hematology accounted for 53% of all publications. Twenty-nine percent of all expanded access patients (N = 197,187) reported on in 2020 and 2021 were treated in the context of COVID-19.
    CONCLUSIONS: By summarizing characteristics of patients, diseases, and research methods described in all scientific literature published on expanded access, we provide a unique dataset for future research. We show that published scientific research on expanded access has surged over the past decades, partly due to COVID-19. However, international collaboration and equity in geographic access remain an issue of concern. Lastly, we stress the need for harmonization of research legislation and guidance on the value of expanded access data within real-world data frameworks to improve equity in patient access and streamline future expanded access research.
    DOI:  https://doi.org/10.1007/s40265-023-01879-4
  82. J Hist Behav Sci. 2023 May 16.
      This article provides a detailed analysis of the intellectual research project of Wilhelm Mann, one of the pioneers of experimental and educational psychology in Chile. Mann's work has been the object of so little analysis that his intellectual influences and networks are not clearly known. We analyzed 338 intratext citations from 22 works by Wilhelm Mann published during the period 1904-1915. As a result, we obtained a mapping of his cooperation networks and used a quantitative approach to study the authors who most influenced his career, among whom were William Stern, Herbert Spencer, Wilhelm Wundt, Alfred Binet, and Ernst Meumann. Mann was closely connected to the international and contemporary advances and discussions of his time, despite the lack of infrastructure and difficulties in communication. Mann was the first psychologist to develop a long-term project in Chile that aimed to measure the individualities of Chilean students and their intellectual development.
    Keywords:  Chile; Wilhelm Mann; citation concept analysis (CCA); educational psychology; experimental psychology; history of psychology
    DOI:  https://doi.org/10.1002/jhbs.22261
  83. Aust Crit Care. 2023 May 10. pii: S1036-7314(23)00056-5. [Epub ahead of print]
       BACKGROUND: Recent studies highlight that female anaesthesiology researchers have lower visibility on professional social networks (PSNs) than male researchers.
    OBJECTIVE: The objective of this work was to compare the use of PSNs between women and men in critical care research.
    METHODS: We included the first/last authors (FAs/LAs) among the most frequently cited articles in 2018 and 2019 in three critical care journals (Intensive Care Medicine, Critical Care Medicine, and Critical Care). We compared the use of three PSNs-Twitter, ResearchGate, and LinkedIn-between women and men in the FA/LA positions.
    RESULTS: We analysed 494 articles, which allowed us to include 426 FAs and 383 LAs. The use of a PSN was similar between women and men (Twitter: 35 vs. 31% FA p = 0.76, 38 vs. 31% LA p = 0.24; ResearchGate: 60 vs. 70% FA p = 0.06, 67 vs. 66% LA p = 0.95; LinkedIn: 54 vs. 56% FA p = 0.25, 68 vs. 64% LA p = 0.58; respectively). On ResearchGate, women had a lower reputation score (FA group 26.4 [19.5-31.5] vs. 34.8 [27.4-41.6], p < 0.01; LA group 38.5 [30.9-43.7] vs. 42.3 [37.6-46.4], p < 0.01) and fewer followers (FA group 28.5 [19-45] vs. 68.5 [72,5-657] p < 0.01; LA group 96.5 [43,8-258] vs. 178 [76.3-313.5] p = 0.02). Female researchers were FAs in 30% of the articles and LAs in 16%.
    CONCLUSION: In the field of critical care, the visibility of female researchers on the social networks dedicated to scientific research is lower than that of male researchers.
    Keywords:  Critical care; Gender; Medical research; Social media; Social network; Women
    DOI:  https://doi.org/10.1016/j.aucc.2023.04.003
  84. J Am Med Inform Assoc. 2023 May 18. pii: ocad082. [Epub ahead of print]
       OBJECTIVE: Identifying consumer health informatics (CHI) literature is challenging. To recommend strategies to improve discoverability, we aimed to characterize controlled vocabulary and author terminology applied to a subset of CHI literature on wearable technologies.
    MATERIALS AND METHODS: To retrieve articles from PubMed that addressed patient/consumer engagement with wearables, we developed a search strategy of textwords and Medical Subject Headings (MeSH). To refine our methodology, we used a random sample of 200 articles from 2016 to 2018. A descriptive analysis of articles (N = 2522) from 2019 identified 308 (12.2%) CHI-related articles, for which we characterized their assigned terminology. We visualized the 100 most frequent terms assigned to the articles from MeSH, author keywords, CINAHL, and Engineering Databases (Compendex and Inspec together). We assessed the overlap of CHI terms among sources and evaluated terms related to consumer engagement.
    RESULTS: The 308 articles were published in 181 journals, more in health journals (82%) than informatics (11%). Only 44% were indexed with the MeSH term "wearable electronic devices." Author keywords were common (91%) but rarely represented consumer engagement with device data, eg, self-monitoring (n = 12, 0.7%) or self-management (n = 9, 0.5%). Only 10 articles (3%) had terminology from all sources (authors, PubMed, CINAHL, Compendex, and Inspec).
    DISCUSSION: Our main finding was that consumer engagement was not well represented in health and engineering database thesauri.
    CONCLUSIONS: Authors of CHI studies should indicate consumer/patient engagement and the specific technology investigated in titles, abstracts, and author keywords to facilitate discovery by readers and expand vocabularies and indexing.
    Keywords:  author keywords; consumer health informatics; controlled vocabulary; patient engagement; wearable devices
    DOI:  https://doi.org/10.1093/jamia/ocad082
  85. Int J Parasitol Parasites Wildl. 2023 Aug;21 89-98
      As the number of known and described parasite species grows every year, one might ask: how much do we actually know about these species beyond the fact they exist? For free-living taxa, research effort is biased toward a small subset of species based on their properties or human-centric factors. Here, using a large data set on over 2500 helminth parasite species described in the past two decades, we test the importance of several predictors on two measures of research effort: the number of times a species description is cited following its publication, and the number of times a species' name is mentioned in the scientific literature. Our analysis highlights some taxonomic biases: for instance, descriptions of acanthocephalans and nematodes tend to receive more citations than those of other helminths, and species of cestodes are less frequently mentioned in the literature than other helminths. We also found that helminths infecting host species of conservation concern receive less research attention, perhaps because of the constraints associated with research on threatened animals, while those infecting host species of human use receive greater research effort. Intriguingly, we found that species originally described by many co-authors subsequently attract more research effort than those described by one or few authors, and that research effort correlates negatively with the human population size of the country where a species was discovered, but not with its economic strength, measured by its gross domestic product. Overall, our findings reveal that we have conducted very little research, or none at all, on the majority of helminth parasite species following their discovery. The biases in study effort we identify have serious implications for future research into parasite biodiversity and conservation.
    Keywords:  Conservation; Human uses; Number of authors; Research effort; Species knowledge; Taxonomy
    DOI:  https://doi.org/10.1016/j.ijppaw.2023.04.010
  86. medRxiv. 2023 May 03. pii: 2023.05.02.23289357. [Epub ahead of print]
      Open science practices are research tools used to improve research quality and transparency. These practices have been used by researchers in various medical fields, though the usage of these practices in the surgical research ecosystem has not been quantified. In this work, we studied the use of open science practices in general surgery journals. Eight of the highest-ranked general surgery journals by SJR2 were chosen and their author guidelines were reviewed. From each journal, 30 articles published between January 1, 2019 and August 11, 2021 were randomly chosen and analyzed. Five open science practices were measured (preprint publication prior to peer-reviewed publication, use of Equator guidelines, study protocol preregistration prior to peer-reviewed publication, published peer review, and public accessibility of data, methods, and/or code). Across all 240 articles, 82 (34%) used one or more open science practices. Articles in the International Journal of Surgery showed greatest use of open science practices, with a mean of 1.6 open science practices compared to 0.36 across the other journals (p<.001). Adoption of open science practices in surgical research remains low, and further work is needed to increase utilization of these tools.
    DOI:  https://doi.org/10.1101/2023.05.02.23289357
  87. Crit Care Med. 2023 May 18.
       OBJECTIVE: To study ICU trials published in the four highest-impact general medicine journals by comparing them with concurrently published non-ICU trials in the same journals.
    DATA SOURCES: PubMed was searched for randomized controlled trials (RCTs) published between January 2014 and October 2021 in the New England Journal of Medicine, The Lancet, the Journal of the American Medical Association, and the British Medical Journal.
    STUDY SELECTION: Original RCT publications investigating any type of intervention in any patient population.
    DATA EXTRACTION: ICU RCTs were defined as RCTs exclusively including patients admitted to the ICU. Year and journal of publication, sample size, study design, funding source, study outcome, type of intervention, Fragility Index (FI), and Fragility Quotient were collected.
    DATA SYNTHESIS: A total of 2,770 publications were screened. Of 2,431 original RCTs, 132 (5.4%) were ICU RCTs, gradually rising from 4% in 2014 to 7.5% in 2021. ICU RCTs and non-ICU RCTs included a comparable number of patients (634 vs 584, p = 0.528). Notable differences for ICU RCTs were the low occurrence of commercial funding (5% vs 36%, p < 0.001), the low number of RCTs that reached statistical significance (29% vs 65%, p < 0.001), and the low FI when they did reach significance (3 vs 12, p = 0.008).
    CONCLUSIONS: In the last 8 years, RCTs in ICU medicine made up a meaningful, and growing, portion of RCTs published in high-impact general medicine journals. In comparison with concurrently published RCTs in non-ICU disciplines, statistical significance was rare and often hinged on the outcome events of just a few patients. Increased attention should be paid to realistic expectations of treatment effects when designing ICU RCTs to detect differences in treatment effects that are reliable and clinically relevant.
    DOI:  https://doi.org/10.1097/CCM.0000000000005937
  88. Nature. 2023 May 19.
      
    Keywords:  Authorship; Policy; Politics; Publishing; Research data
    DOI:  https://doi.org/10.1038/d41586-023-01705-7
  89. Behav Anal Pract. 2023 Jun;16(2): 388-398
      Procedural integrity refers to the extent to which an independent variable is implemented as described. Measuring procedural integrity is one important factor when considering internal and external validity of experiments. Experimental articles in behavior-analytic journals have rarely reported procedural-integrity data. The purpose of this study was to update previous reviews of whether articles published in the Journal of Applied Behavior Analysis reported procedural integrity, spanning a period from 1980 to 2020, and compare reporting in JABA to recent reviews of studies published in Behavior Analysis in Practice (2008-2019) and the Journal of Organizational Behavior Management (2000-2020). Procedural integrity continues to be underreported across all three journals, but an increasing trend in reporting procedural integrity is evident in the Journal of Applied Behavior Analysis and Behavior Analysis in Practice. In addition to our recommendations and implications for research and practice, we provide examples and resources to assist researchers and practitioners with recording and reporting integrity data.
    Keywords:  Adherence; Fidelity; Procedural integrity; Publication practices; Treatment integrity
    DOI:  https://doi.org/10.1007/s40617-022-00741-5
  90. Am J Sports Med. 2023 May 15. 3635465231169042
       BACKGROUND: Spin is a reporting bias that misrepresents research. Ultimately it can affect surgeon decision making and patient care. Anterior cruciate ligament (ACL) reconstruction is common, but debate continues over optimal treatment modalities.
    PURPOSE: To identify the prevalence of spin in meta-analysis and systematic review abstracts regarding the treatment of ACL injuries with quadriceps tendon graft.
    STUDY DESIGN: Cross-sectional study.
    METHODS: Electronic libraries (MEDLINE, Embase, Web of Science, Google Scholar) were searched for meta-analyses and systematic reviews regarding the treatment of ACL tears with quadriceps tendon graft. The 9 most severe types of spin commonly found in abstracts were used as an evaluation tool to assess the articles. Two reviewers each performed a blinded assessment of each article for spin. A third reviewer helped after review was done to address any discrepancies between the original reviewers. Further evaluation included year of publication, number of citations, journal impact factor, and A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR-2) score.
    RESULTS: The electronic database search resulted in 986 articles, of which 13 met our inclusion criteria. After review, we found that 53.8% (7/13) of the included articles contained 1 of the 9 most severe forms of spin. Of the 13 articles, 15.4% (n = 2) contained 2 types of spin, and 38.5% (n = 5) contained 1 type of spin. No studies contained ≥3 types of spin. Of the types of spin evaluated, the most prevalent (n = 4; 30.8%) was type 3 ("selective reporting of or overemphasis on efficacy outcomes or analysis favoring the beneficial effect of the experimental intervention"). All studies, regardless of the presence of spin, were found to be low or critically low quality according to the AMSTAR-2 assessment.
    CONCLUSION: This study demonstrated the presence of spin in 53.8% of meta-analysis and systematic review abstracts pertaining to quadriceps tendon graft for ACL reconstruction. Orthopaedic surgeons should learn to recognize spin as they review articles when deciding the treatment course for ACL injuries. Additionally, strict criteria should be considered to reduce the prevalence of spin in orthopaedic literature.
    Keywords:  ACL reconstruction; bias; orthopaedics; quadriceps tendon; spin
    DOI:  https://doi.org/10.1177/03635465231169042