bims-evares Biomed News
on Evaluation of research
Issue of 2023–01–29
eighty papers selected by
Thomas Krichel, Open Library Society
  1. A Bibliometric Analysis of the Top 50 Most Influential Articles on External Ventricular Drains.
  2. A bibliometric analysis of studies on the gut microbiota in cardiovascular disease from 2004 to 2022.
  3. The top 100 most cited papers in insomnia: A bibliometric analysis.
  4. Bibliometric analysis of research trends in relationship between sarcopenia and surgery.
  5. Research topics and hotspot trends of lumbar spondylolisthesis: A text-mining study with machine learning.
  6. Trends of rhinoplasty research in the last decade with bibliometric analysis.
  7. Global research trends and hotspots in calcaneal fracture: A bibliometric analysis (2000-2021).
  8. The top 100 most-cited articles on adult spinal deformity: The most popular topics are still sagittal plane parameters and complications.
  9. Research status and hotspots of medication safety in older adults: A bibliometric analysis.
  10. Analysis of the Most Frequently Cited Articles in Hand and Wrist Surgery: A Modern Reading List.
  11. Bibliometric analysis of global research profile on ketogenic diet therapies in neurological diseases: Beneficial diet therapies deserve more attention.
  12. Global research trends in penile cancer: Bibliometric and visualized analysis.
  13. Peri-implantitis: A bibliometric network analysis of top 100 most-cited research articles.
  14. A bibliometric analysis of hidradenitis suppurativa literature over the past 50 years.
  15. Research landscape and trends of melanoma immunotherapy: A bibliometric analysis.
  16. Global trends in polycystic ovary syndrome research: A 10-year bibliometric analysis.
  17. Research trends on the relationship between gut microbiota and colorectal cancer: A bibliometric analysis.
  18. A global bibliometric analysis on Kawasaki disease research over the last 5 years (2017-2021).
  19. Research hotspots and trends in visceral pain research: A global comprehensive bibliometric analysis.
  20. Knowledge mapping concerning applications of nanocomposite hydrogels for drug delivery: A bibliometric and visualized study (2003-2022).
  21. Researching trends in pemphigoid diseases: A bibliometric study of the top 100 most cited publications.
  22. Health literacy in childhood and adolescence. A bibliometric analysis of scientific publications and professionals' involvement.
  23. Knowledge domain and dynamic patterns in multimodal molecular imaging from 2012 to 2021: A visual bibliometric analysis.
  24. Bibliometric and visualization analysis of research trend in mental health problems of children and adolescents during the COVID-19 pandemic.
  25. Research trends, developments, and future perspectives in brand attitude: A bibliometric analysis utilizing the Scopus database (1944-2021).
  26. Bibliometric and visualized analysis of sodium-Glucose cotransporter 2 inhibitors.
  27. Global trends and hotspots of phage therapy for bacterial infection: A bibliometric visualized analysis from 2001 to 2021.
  28. Global research trends in catheter ablation and surgical treatment of atrial fibrillation: A bibliometric analysis and science mapping.
  29. Knowledge domains and emerging trends of microglia research from 2002 to 2021: A bibliometric analysis and visualization study.
  30. Global research hot spot and trends in tinnitus treatment between 2000 and 2021: A bibliometric and visualized study.
  31. Artificial intelligence applicated in gastric cancer: A bibliometric and visual analysis via CiteSpace.
  32. Mapping knowledge landscapes and emerging trends of sonodynamic therapy: A bibliometric and visualized study.
  33. Global Research Status Regarding Uveitis in the Last Decade.
  34. Bibliometric and visual analysis of cerebral revascularization from 1999 to 2022.
  35. A bibliometric analysis of telerehabilitation services for patients with stroke.
  36. Predictors of Citations for Original Research in Ophthalmology.
  37. Gender differences in pulmonology and critical care authorship and editorial boards.
  38. Comprehensive analysis of global research on overactive bladder: A scientometric approach.
  39. Bibliometric analysis of scientific papers on extracellular vesicles in kidney disease published between 1999 and 2022.
  40. Bibliometric analysis of the effects of mental fatigue on athletic performance from 2001 to 2021.
  41. Nationwide Bibliometric Analysis of Integrated Plastic Surgery Program Directors.
  42. Global research into the relationship between electronic waste and health over the last 10 years: A scientometric analysis.
  43. Global trends in research of immune cells associated with hypertensive disorders of pregnancy: A 20-year bibliometric analyses (from 2001 to 2021).
  44. Bibliometric analysis on the adoption of artificial intelligence applications in the e-health sector.
  45. Global research trends in the COVID-19 and digestive disease: A review of visualization and bibliometric study.
  46. General practice-based cancer research publications: a bibliometric analysis 2013-2019.
  47. Knowledge mapping of COVID-19 and dentistry: A bibliometric analysis.
  48. Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis.
  49. Bibliometric analysis of traditional Chinese medicine research on heart failure in the 21st century based on the WOS database.
  50. A bibliometric analysis on the progress of myocardial bridge from 1980 to 2022.
  51. A Bibliometric Mapping Study of the Literature on Oral Health-related Quality of Life.
  52. CiteSpace-based global science, technology, engineering, and mathematics education knowledge mapping analysis.
  53. Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis.
  54. Trends of denosumab-related publications in web of science.
  55. Fate of Abstracts Presented at the Saudi Ophthalmology Society Conferences 2015-2018.
  56. Palliative care and COVID-19: a bibliometric analysis.
  57. Comparison of Gamification, Game-Based Learning, and Serious Games in Medical Education: A Scientometrics Analysis.
  58. The latest research trends in the removal of cesium from radioactive wastewater: A review based on data-driven and visual analysis.
  59. Bibliometric Analysis of the Neurosurgery Publication Productivity of Southeast Asia in the Previous Decade.
  60. Factors Associated with the Success and Timing of Orthopaedic Surgery Resident Research Thesis Project Publication.
  61. Diseases spectrum in the field of spatiotemporal patterns mining of infectious diseases epidemics: A bibliometric and content analysis.
  62. Correlations between the selection of topics by news media and scientific journals.
  63. A bibliometric analysis of preoperative anxiety research (2001-2021).
  64. Bibliometric evaluation of 2011-2021 publications on hydrogen sulfide in heart preservation research.
  65. Authorship by gender in anesthesiology journals: a retrospective cross-sectional study for Japan.
  66. Development and status of moral education research: Visual analysis based on knowledge graph.
  67. Knowledge atlas of antibody-drug conjugates on CiteSpace and clinical trial visualization analysis.
  68. Bibliometric analyses of social media for educational purposes over four decades.
  69. Gender differences and cooperation in medical authorships - an analysis of the recent ten years in five key medical disciplines.
  70. Scientometric review of research on Neglected Tropical Diseases: a 31-year perspective from the Journal of the Brazilian Society of Tropical Medicine.
  71. Corrigendum: Evolution of research trends in artificial intelligence for breast cancer diagnosis and prognosis over the past two decades: A bibliometric analysis.
  72. Bibliometric analysis of cancer research outputs in Botswana between 2009 and 2021.
  73. An Analysis of Vascular Surgery Education Publications reveals an educational shortage.
  74. Gender differences in academic productivity, educational positions, and leadership appointments of physicians in the U.S.
  75. Human Robot Collaboration in Industry 4.0: a literature review.
  76. Using the rear-view mirror to look forward.
  77. Visual analysis of environmental research progress in Germany linking Development Anthropology: A sustainable approach based on the Web of Science.
  78. Panel composition and disparities in the topics of presentation in vascular surgery conferences.
  79. Gender Disparities in Cardiac Surgery Trials: Leadership, Authorship, and Patient Enrollment.
  80. Correction: Citation impact and social media visibility of Great Barrington and John Snow signatories for COVID-19 strategy.
  1. World Neurosurg. 2023 Jan 18. pii: S1878-8750(23)00054-2. [Epub ahead of print]
    A Bibliometric Analysis of the Top 50 Most Influential Articles on External Ventricular Drains.
    Catherine Lei, Frank A De Stefano, Cody Heskett, Lane Fry, Kevin Le, Aaron Brake, Kevin Chatley, Jeremy Peterson, Koji Ebersole.
       OBJECTIVE: External ventricular drains (EVDs) are commonly used to remove cerebrospinal fluid (CSF) and monitor intracranial pressure in patients with neurological dysfunction. Often the first invasive procedure learned in training, ventricular drain placement is the quintessential neurosurgical procedure. This bibliometric analysis highlights the top contributing EVD articles in current evidence-based practice.
    METHODS: The Scopus database was used to perform a title-specific, keyword-based search for all publications until September 2022. The keywords "external ventricular drain" or "EVD" or "external ventriculostomy" were used. The 50 most cited articles were selected for analysis. Parameters included the following: title, citation count, citations per year, authors, specialty of first author, institution, country of origin, publishing journal, Source Normalized Impact Per Paper (SNIP), and Hirsch index.
    RESULTS: The keyword-based search showed that 8464 articles on EVDs were published between 1991 and 2022. The top 50 articles were published between 1999 and 2019. The top 50 articles acquired a total of 3343 citations with an average of 66.86 citations per paper. The rate of self-citations accounted for an average of 5.16% of the total number of citations. A majority of the top 50 articles focused on EVD infection and placement accuracy. The first and second most cited papers were authored by Zabramski et al. and Fried et al., respectively.
    CONCLUSION: The bibliometric analysis provides a quantitative overview of how topics and interventions are analyzed in academic medicine. In the present study, we evaluated the global trends in EVDs by analyzing the top 50 most cited papers.
    Keywords:  bibliometric analysis; external ventricular drain; neurosurgery
    DOI:  https://doi.org/10.1016/j.wneu.2023.01.040
  2. Front Cell Infect Microbiol. 2022 ;12 1083995
    A bibliometric analysis of studies on the gut microbiota in cardiovascular disease from 2004 to 2022.
    Ming Sheng, Shuquan Xu, Wei-Wei Chen, Fa-Quan Li, Yi-Ming Zhong, Yi-Xiang Ouyang, Yong-Ling Liao, Ping Lai.
       Background: Increasing evidence indicates that the gut microbiota (GM) is linked to cardiovascular disease (CVD). Many studies on the GM in CVD have been published in the last decade. However, bibliometric analysis in this field is still lacking.
    Methods: On 30 September 2022, a search of the Web of Science™ (WoS; Clarivate™, Philadelphia, PA, USA) yielded 1,500 articles and reviews on the GM and CVD. Microsoft Excel and CiteSpace and VOSviewer software were used to analyze publication trends and research hotspots in this field.
    Results: Our search generated 1,708 publications on the GM in CVD published between 2004 and 2022, and 1,500 articles and review papers were included in the final analysis. The number of publications relating to the GM in CVD increased from 1 in 2004 to 350 in 2021. China (485 publications, 9,728 non-self-citations, and an H-index of 47) and the USA (418 publications, 24,918 non-self-citations, and an H-index of 82) contributed 32.31%, and 27.85%, respectively, of the total number of publications. Examination of the number of publications (Np) and number of citations, excluding self-citations (Nc), of individual authors showed that Y. L. Tian (Np: 18, Nc: 262, and H-index: 12), from China, is the most productive author, followed by R. Knight (Np: 16, Nc: 3,036, and H-index: 15) and M. Nieuwdorp (Np: 16, Nc: 503, and H-index: 9). The Chinese Academy of Medical Sciences and Peking Union Medical College accounted for the largest number of publications (Np: 62, Nc: 3,727, and H-index: 13, average citation number (ACN): 60.11). The journal Nutrients had the most publications (Np: 73, Nc: 2,036, and ACN: 27.89). The emerging keywords in this field were "monooxygenase 3" (strength 3.24, 2020-2022), "short-chain fatty acid" (strength 4.63, 2021-2022), "fatty liver disease" (strength 3.18, 2021-2022), "metabolic disease" (strength 3.04, 2021-2022), "Mediterranean diet" (strength 2.95, 2021-2022), "prevention" (strength 2.77, 2021-2022), and "intestinal barrier" (strength 2.8, 2021-2022).
    Conclusion: Publications on the GM in CVD rapidly increased in the last decade. The USA was the most influential country in publications in this field, followed by China. The journal with the most publications was Nutrients. Monooxygenase-3, short-chain fatty acids, fatty liver disease, metabolic disease, the Mediterranean diet, intestinal barrier, and prevention are the current hotspots or potential hotspots for future study.
    Keywords:  CiteSpace; VOSviewer; WoS; bibliometric analysis; cardiovascular diseases; gut microbiota
    DOI:  https://doi.org/10.3389/fcimb.2022.1083995
  3. Front Psychiatry. 2022 ;13 1040807
    The top 100 most cited papers in insomnia: A bibliometric analysis.
    Qingyun Wan, Kai Liu, Xiaoqiu Wang, Shuting Luo, Xiya Yuan, Chi Wang, Jing Jiang, Wenzhong Wu.
       Objective: The number of citations to a paper represents the weight of that work in a particular area of interest. Several highly cited papers are listed in the bibliometric analysis. This study aimed to identify and analyze the 100 most cited papers in insomnia research that might appeal to researchers and clinicians.
    Methods: We reviewed the Web of Science (WOS) Core Collection database to identify articles from 1985 to 24 March 2022. The R bibliometric package was used to further analyze citation counts, authors, year of publication, source journal, geographical origin, subject, article type, and level of evidence. Word co-occurrence in 100 articles was visualized using VOS viewer software.
    Results: A total of 44,654 manuscripts were searched on the Web of Science. Between 2001 and 2021, the top 100 influential manuscripts were published, with a total citation frequency of 38,463. The top countries and institutions contributing to the field were the U.S. and Duke University. Morin C.M. was the most productive author, ranking first in citations. Sleep had the highest number of manuscripts published in the top 100 (n = 31), followed by Sleep Medicine Reviews (n = 9). The most cited manuscript (Bastien et al., Sleep Medicine, 2001; 3,384 citations) reported clinical validation of the Insomnia Severity Index (ISI) as a brief screening indicator for insomnia and as an outcome indicator for treatment studies. Co-occurrence analyses suggest that psychiatric disorders combined with insomnia and cognitive behavioral therapy remain future research trends.
    Conclusion: This study provides a detailed list of the most cited articles on insomnia. The analysis provides researchers and clinicians with a detailed overview of the most cited papers on insomnia over the past two decades. Notably, COVID-19, anxiety, depression, CBT, and sleep microstructure are potential areas of focus for future research.
    Keywords:  VOSviewer; bibliometric analysis; citations; insomnia; trends
    DOI:  https://doi.org/10.3389/fpsyt.2022.1040807
  4. Front Surg. 2022 ;9 1056732
    Bibliometric analysis of research trends in relationship between sarcopenia and surgery.
    Tao Liu, Fengjing Song, Deqiang Su, Xiaofeng Tian.
       Background: The relationship between sarcopenia and surgery has attracted an increasing number of researchers in recent years. Our study aimed to identify the current research hotspot and status in this field by using bibliometric and visualization analysis.
    Methods: Publications about the relationship between sarcopenia and surgery that met the inclusion criteria were collected from the Science Citation Index Expanded. The bibliometric and visualized studies were performed using VOSviewer, and R.
    Results: A total of 2,261 documents on the relationship between sarcopenia and surgery were included in our study. These articles were written by 13,757 authors from 2,703 institutions in 70 countries and were published in 772 journals. The USA is the most productive and influential country in this field (524 publications and 15,220 citations). The Udice French Research Universities was the most productive institution in this field (57 publications), and the University of Alberta had the largest number of citations. Annuals of Surgical Oncology published the most studies in this field. Shen Xian was the most productive author in this field (number of publications = 19), and Baracos Vickie was the most influential author, whose studies in this field had been cited 2,209 times. The cluster analysis was performed and visualized, and the keywords were classified into 6 clusters: Cluster 1 (body composition and nutrition), Cluster 2 (sarcopenia), Cluster 3 (malnutrition and cachexia), Cluster 4 (cancer surgery), Cluster 5 (elderly and frailty), Cluster 6 (neuromuscular scoliosis).
    Conclusion: The relationship between sarcopenia and surgery was still a controversial and well-discussed topic in recent years. Our study showed that the study in this field mainly focused on sarcopenia, oncology surgery, orthopedics, and nutrition.
    Keywords:  bibliometric analysis; oncology; orthopedics; sarcopenia; surgery; visualized study
    DOI:  https://doi.org/10.3389/fsurg.2022.1056732
  5. Front Surg. 2022 ;9 1037978
    Research topics and hotspot trends of lumbar spondylolisthesis: A text-mining study with machine learning.
    Guoxin Fan, Yufeng Li, Sheng Yang, Jiaqi Qin, Longfei Huang, Huaqing Liu, Shisheng He, Xiang Liao.
       Objectives: The study aimed to conduct a bibliometric analysis of publications concerning lumbar spondylolisthesis, as well as summarize its research topics and hotspot trends with machine-learning based text mining.
    Methods: The data were extracted from the Web of Science Core Collection (WoSCC) database and then analyzed in Rstudio1.3.1 and CiteSpace5.8. Annual publication production and the top-20 productive authors over time were obtained. Additionally, top-20 productive journals and top-20 influential journals were compared by spine-subspecialty or not. Similarly, top-20 productive countries/regions and top-20 influential countries/regions were compared by they were developed countries/regions or not. The collaborative relationship among countries and institutions were presented. The main topics of lumbar spondylolisthesis were classified by Latent Dirichlet allocation (LDA) analysis, and the hotspot trends were indicated by keywords with strongest citation bursts.
    Results: Up to 2021, a total number of 4,245 articles concerning lumbar spondylolisthesis were finally included for bibliometric analysis. Spine-subspecialty journals were found to be dominant in the productivity and the impact of the field, and SPINE, EUROPEAN SPINE JOURNAL and JOURNAL OF NEUROSURGERY-SPINE were the top-3 productive and the top-3 influential journals in this field. USA, Japan and China have contributed to over half of the publication productivity, but European countries seemed to publish more influential articles. It seemed that developed countries/regions tended to produce more articles and more influential articles, and international collaborations mainly occurred among USA, Europe and eastern Asia. Publications concerning surgical management was the major topic, followed by radiographic assessment and epidemiology for this field. Surgical management especially minimally invasive technique for lumbar spondylolisthesis were the recent hotspots over the past 5 years.
    Conclusions: The study successfully summarized the productivity and impact of different entities, which should benefit the journal selection and pursuit of international collaboration for researcher who were interested in the field of lumbar spondylolisthesis. Additionally, the current study may encourage more researchers joining in the field and somewhat inform their research direction in the future.
    Keywords:  bibliometrics; latent dirichlet allocation; lumbar spondylolisthesis; machine learning; text mining
    DOI:  https://doi.org/10.3389/fsurg.2022.1037978
  6. Front Surg. 2022 ;9 1067934
    Trends of rhinoplasty research in the last decade with bibliometric analysis.
    Xuanru Zhu, Bin Zhang, Yuesheng Huang.
       Background: As rhinoplasty (RP) with different requirements is becoming more and more popular in the latest decade, this study aims to quantitatively and qualitatively explore the trends in RP research, depict research hotspots, and point out the future direction with a bibliometric analysis.
    Methods: All RP literature studies in the last decade (from 2012 to 2021) were retrieved from the Web of Science Core database. Annual output, institutions, authors, journals, and most-cited literature studies were analyzed by bibliometric tools, including CiteSpace, bibliometric online platform, bibliometrix R language kit, BICOMB, and gCLUTO.
    Results: A total of 2,590 RP research studies dated between 2012 and 2021 were included according to our criterion. As for the country, the United States, Turkey, and Korea maintained the top three in RP research. As for the institutions, the University of California, Irvine, Stanford University, and University of Ulsan ranked top three in RP research publications based on article counts. Professor Rhorich RJ, Most SP, and Jang YJ were the most contributed authors according to article counts and citation number. The top journals were The Plastic and Reconstructive Surgery, JAMA Facial Plastic Surgery, and Aesthetic Surgery Journal. The 10 most-cited literature studies were also listed explicitly in this study. Finally, biclustering analysis on the most frequent keywords were conducted which helped us to identify seven hotspot clusters in RP research.
    Conclusions: We comprehensively summarized the publication information of RP literature studies in the past decade, highlighted the current status and trends over time, and provide guidance for in-depth research direction on RP for the future.
    Keywords:  3D anthropometry; bibliometric analysis; hotspots; outcome evaluation; rhinoplasty
    DOI:  https://doi.org/10.3389/fsurg.2022.1067934
  7. Front Surg. 2022 ;9 940432
    Global research trends and hotspots in calcaneal fracture: A bibliometric analysis (2000-2021).
    Yang-Ting Cai, Yu-Ke Song, Min-Cong He, Xiao-Ming He, Qiu-Shi Wei, Wei He.
       Background: Calcaneal fracture is common and carries high morbidity and disability. Its treatment is therefore of vital concern. Many topics concerning calcaneal fracture remain controversial, and the subject has not yet been well-researched. We aim to analyze and illustrate the trends in development, overall knowledge structure, "hotspots," and research frontiers on the topic of calcaneal fracture.
    Methods: Literature relating to calcaneal fracture published between 2000 and 2021 was retrieved from Science Citation Index Expanded (SCIE) database of the Web of Science. Three bibliometric tools (Bibliometrix, CiteSpace, and VOSviewer software) were used for analysis and the generation of knowledge maps. Annual trends in publication counts and the relative contributions of different countries, regions, institutions, authors, and journals, as well as keyword clusters, "hot topics," and research frontiers, were analyzed.
    Results: A total of 1,687 publications were included in the analysis. The number of calcaneal fracture articles published worldwide each year was highest in 2019, with a total of 128 articles. The United States has made the greatest contribution to the field, with the largest number of publications and the highest H-index. Foot & Ankle International was the most productive journal, publishing a total of 167 articles on calcaneal fracture during the study period. Hebei Medical University of China and the University of California, San Francisco were the most prolific institutions. Professors T. Schepers, S. Rammelt, H. Zwipp, and Y. Z. Zhang have made remarkable contributions to the field. However, the degree of collaboration between researchers and among institutions was relatively low, and took place mainly in Europe and the Americas. All relevant keywords could be categorized into three clusters: studies of internal fixation, studies of fractures, and studies of osteoporosis. A trend of balanced and diversified development could be seen within these clusters. Keywords with ongoing "citation bursts," such as sinus tarsi approach, wound complications, minimally invasive technique, extensile lateral approach, surgical treatment, and plate, may continue to be research "hotspots" in the near future.
    Conclusion: Based on current global trends, the number of publications on calcaneal fracture will continue to increase. Topics such as minimally invasive techniques and complications have become important hotspots of research. We recommend enhancing international communication and collaboration for future research in this field.
    Keywords:  bibliometric analysis; calcaneal fractures; hotspots; research trends; visualization
    DOI:  https://doi.org/10.3389/fsurg.2022.940432
  8. Front Surg. 2022 ;9 961582
    The top 100 most-cited articles on adult spinal deformity: The most popular topics are still sagittal plane parameters and complications.
    Fu-Sheng Liu, Lin-Xia Deng, Fu-Bing Liu, Qian-Shi Zhang, Xiao-Bin Wang, Jing Li.
       Purpose: This study aimed to summarize the characteristics of the 100 most-cited articles on adult spinal deformity (ASD) and to analyze past and current research hotspots and trends.
    Methods: Literature searches (from inception to 28 April 2022) using Web of Science databases were conducted to identify ASD-related articles. The top 100 most-cited articles were collected for further analysis. Meanwhile, author keywords from articles published in the last 5 years were selected for further analysis.
    Results: The top 100 most-cited articles on ASD were selected from 3,354 papers. The publication year ranged from 1979 to 2017, and all papers were written in English. The citation count among them ranged from 100 to 1,145, and the mean citation number was 215.2. The foremost productive first author was Schwab F. University of Washington had the largest number of publications. The United States of America had the largest number of published articles (n = 84) in this field. Spine was the most popular journal. Complications were the most studied themes. The visualization analysis of author keywords from the literature in the recent 5 years showed that complications, sagittal plane parameters, and surgical techniques are still the research hotspots, and minimally invasive surgery will continue to develop rapidly.
    Conclusion: Based on a comparative analysis of the results of bibliometric and visualization, complications and sagittal plane parameters are still the major topics of research at present and even later, and minimally invasive surgery has a growth trend in this field of ASD.
    Keywords:  adult spinal deformity; bibliometric; most-cited articles; trends; visualization analysis
    DOI:  https://doi.org/10.3389/fsurg.2022.961582
  9. Front Public Health. 2022 ;10 967227
    Research status and hotspots of medication safety in older adults: A bibliometric analysis.
    Chuantao Xie, Yanhong Gu, Yanan Wang, Feixia Ni, Yumei Li.
       Background: Medication safety is a significant concern in healthcare. Research on medication safety for older adults has taken a broad approach, resulting in a range of proposals. At this juncture, it is necessary to identify the main contributors and establish the current developmental status of the principal research topics.
    Objective: This study sets out to summarize the state-of-the-art in medication safety for older adults, identifying significant achievements, key topics, and emerging trends.
    Methods: The Web of Science Core Collection (WOSCC) database was searched for relevant documentation over the interval 1st January 2000 to 31st December 2021. Annual outputs and citations were identified from the WOS citation reports. CiteSpace and VOSviewer were adopted for bibliometric analysis and visualization that included the distribution of countries/regions, organizations, authors and journals, and an analysis of co-cited references and keywords.
    Results: A total of 1,638 documents were retrieved for bibliometric analysis, yielding 34.29 citations per document. Publications have increased over the past two decades, reaching 177 outputs in 2019. Our database encompasses 71 countries/regions, 2,347 organizations, and 7,040 authors. The United States ranks first in terms of scientific activity with 604 publications (36.87%). We have identified the University of Sydney as the most prolific organization (53 publications). J. T. Hanlon, J. H. Gurwitz, D. O'Mahony, and G. Onder are the most influential researchers in terms of publications and citations. The Journal of the American Geriatrics Society ranks first with 89 (5.43%) papers. In terms of major research directions, three topics have been identified from co-cited reference and keyword analysis: (1) estimation of the prevalence and variables associated with polypharmacy and potentially inappropriate medication; (2) analysis of interventions involving pharmacists and the associated impact; (3) patient experience and perception associated with medication use or pharmaceutical care.
    Conclusion: Research on medication safety for older adults has progressed significantly over the past two decades. The United States, in particular, has made important contributions to this field. Polypharmacy and potentially inappropriate medication use, interventions involving pharmacists, patient experience and perception represent the current focus of research. Our findings suggest that these directions will continue as research hotspots in the future.
    Keywords:  aged; bibliometric analysis; hotspots; inappropriate prescribing; medication safety; patient safety; polypharmacy; research trends
    DOI:  https://doi.org/10.3389/fpubh.2022.967227
  10. Cureus. 2022 Dec;14(12): e32690
    Analysis of the Most Frequently Cited Articles in Hand and Wrist Surgery: A Modern Reading List.
    Stephanie Delma, Yagiz Ozdag, Eugene P Warnick, Jessica Baylor, Louis C Grandizio.
      The aim of this investigation was to analyze the 50 most frequently cited articles on hand and wrist surgery of all time and those published during the 21st century. We aimed to evaluate the article, author, and journal characteristics for these publications in order to create a modern reading list of impactful upper-extremity articles. A search of the Journal Citation Reports 2022 edition to identify journals containing possible hand or wrist-related articles was performed. Related journals were identified and then searched on the Web of Science database to identify hand and wrist articles. The top 50 most cited articles overall and the top 50 most cited articles from 2000-2021 were identified and indexed. Several bibliometric parameters, such as study type, study topic, study design, level of evidence, citation count, citation density, the institution of the lead author, the gender of lead and senior authors, and country were analyzed. For the most cited articles of all time, the number of citations ranged from 224 to 1109 with a mean of 368 citations and 15.0 citation density. Citations for the top 50 articles from 2000-2021 ranged from 153 to 950 with a mean of 233 citations and 14.5 citation density. For both groups, the most common level of evidence was level IV (33% and 27%). No correlation between journal impact factor and citation count or citation density was found. In both groups, "fracture" was the most common topic and papers were predominantly written by male authors. Frequently cited publications on hand and wrist surgery are often clinical papers that contain low levels of evidence and tend to focus on topics related to fracture care. Female authors remain underrepresented.
    Keywords:  bibliometric analysis; citations; hand surgery; orthopaedic surgery; wrist surgery
    DOI:  https://doi.org/10.7759/cureus.32690
  11. Front Endocrinol (Lausanne). 2022 ;13 1066785
    Bibliometric analysis of global research profile on ketogenic diet therapies in neurological diseases: Beneficial diet therapies deserve more attention.
    Yinuo Wang, Junyao Zhang, Yingying Zhang, Junyan Yao.
       Background: The protective effects of Ketogenic Diet Therapies (KDTs) on neurological diseases have been extensively studied over the past two decades. The purpose of this study was to quantitatively and qualitatively analyze the publication of KDTs in the neurological field from 2000 to 2021.
    Methods: A literature search was performed on June 7th, 2022, using the search terms: (("ketone" OR "ketogenic" OR "*hydroxybuty*") AND ("neuro*")) in the WoSCC database. Collected data were further analyzed using VOSviewer, CiteSpace and other online bibliometric websites. The annual publication volume and citation trends were summarized. The collaborations among highly cited countries, institutions, authors and journals were visualized. The co-citation analysis of highly cited references and journals were also visualized. Moreover, the research focuses and fronts were revealed by co-occurrence analysis and burst keywords detection.
    Results: A total of 2808 publications with 88,119 citations were identified. From 2000-2021, the number of publications and citations presented rising trends. The United States was the country with an overwhelming number of publications and cited times. Johns Hopkins University was the most contributory institution. Kossoff Eric H was the author with the largest number of publications. And Epilepsia was both the largest publisher and the most frequently cited journal. The keywords of intense interest involved "Modified Atkins Diet", "Temporal Lobe Epilepsy", "Alzheimer's Disease", "Parkinson's Disease", "Cerebral Blood Flow", "Neuroinflammation", "Oxidative Stress", "Metabolism" and "Mitochondria".
    Conclusion: We presented the global trend of KDTs in neurological diseases and provided important information for relevant researchers in a bibliometric way. This bibliometric study revealed that treating epilepsy, neuroprotection and functional effects of KDTs on mitochondria and oxidative stress have been the spotlight from 2000 to 2021. These have emerged as the basis for transformation from basic research to clinical application of KDTs.
    Keywords:  Citespace; Ketogenic Diet; Neurological Diseases; Neuroprotection; Oxidative Stress; VOSviewer; bibliometric analysis; hotspots
    DOI:  https://doi.org/10.3389/fendo.2022.1066785
  12. Front Oncol. 2022 ;12 1091816
    Global research trends in penile cancer: Bibliometric and visualized analysis.
    Sheng Deng, Zhihua Xuan, Junlong Feng, Haisong Li, Bin Wang, Zhen Yang, Lihua Xuan, Fanchao Meng, Lu Wang, Yangchun Xiao, Jisheng Wang.
       Background: Penile cancer is a malignant tumor of the genitourinary system that mostly occurs in middle-aged and elderly men aged 50-70 years, which can seriously affect physical, psychological, and sexual health. Hundreds of original articles and reviews on penile cancer are published each year. However, a bibliometric analysis of these publications has not been performed.
    Objective: This study aimed to systematically analyze and visualize penile cancer-related publications through bibliometrics and reveal identified topics, hotspots, and knowledge gaps in related fields.
    Methods: Based on the Web of Science core collection database, we first analyzed the quantity and quality of publications in the field of penile cancer. Second, we profiled the publishing groups in terms of country, institution, author's publication, and cooperation network. Then, we systematized and summarized the hot topics of research.
    Results: This bibliometric analysis was conducted from 2001 to 2022. The analysis identified 1,687 articles and reviews, which were published in 432 journals. The number of publications and citations on penile cancer-related research has steadily increased over the last two decades. Furthermore, academic institutions in Europe and the United States play a leading role in penile cancer research. The country, institution, journal, and author with the most publications were the United States (507), H Lee Moffitt Cancer Research Center (96), Journal of Urology (83), and Spiess P (87), respectively. The most frequently used keywords were penile cancer (743), squamous-cell carcinoma (717), cancer (380), carcinoma (232), lymphadenectomy (229). 16 keyword clustering information was obtained, including #0 male circumcision, #1 lichen sclerosus, #2 chemotherapy, #3 penile neoplasms, #4 targeted therapy, #5 resection margin, #6 cervical cancer, #7 lymph node dissection, #8 prognostic factor, #9 prostate cancer, #10 inguinal lymph node dissection, #11 human papillomavirus DNA, #12 gene, #13 penile intraepithelial neoplasia, #14 male sexual function, and #15 penile cancer.
    Conclusion: More and more scholars are devoted to the research on penile cancer. This bibliometric analysis revealed that the main research topics and hotspots in penile cancer included risk factors and surgical treatment plans.
    Keywords:  bibliometrics; data visualization; hotspots; penile cancer; research status
    DOI:  https://doi.org/10.3389/fonc.2022.1091816
  13. Clin Implant Dent Relat Res. 2023 Jan 23.
    Peri-implantitis: A bibliometric network analysis of top 100 most-cited research articles.
    Hamoun Sabri, Hom-Lay Wang.
       BACKGROUND: Over the past decades, there has been an increase in research publications focusing on peri-implantitis. When facing limited healthcare resources, bibliometric analyses can guide researchers and funding parties toward areas where reallocation or more focus on research activity is warranted. The main objective of this study was to identify the trends of the top 100 cited articles on peri-implantitis research as the first study of its kind.
    METHODS: A Web of Science search, using the keywords "peri-implantitis or periimplantitis" was built to create a database of the most-cited articles. Articles were ranked by citation count and screened by two independent reviewers. The bibliometric characteristics of the studies were gathered and analyzed using several bibliometric software. Author collaborations, author clusters, and keyword co-occurrence network analyses were also performed. The correlation between the citation count and the age of each article was tested.
    RESULTS: The top 100 cited papers were published from 1994 to 2018 and the total citation counts ranged from 119 to 972 with 244.5 citations/paper on average. There was no correlation between the age of the articles and the citation count (p-value = 0.67). 21% of the studies consisted of prospective clinical studies. 35% of the papers focused on treatment and prevention of peri-implantitis while 65% concerned epidemiology. The top three most prolific countries were Sweden (n = 31), Germany (n = 15), and Switzerland (n = 13). We found 12 authors who had greater than five publications on the list. Also, the most published journal was Clinical Oral Implants Research.
    CONCLUSION: This study provides insight into the characteristics and quality of the most highly cited peri-implantitis literature. This revealed a deficiency in terms of the number of studies on treatment strategies as well as a higher level of evidence studies among the most- impactful papers on peri-implantitis at the moment.
    Keywords:  bibliometric analysis; bibliometrics; dental implants; peri-implantitis; web of science
    DOI:  https://doi.org/10.1111/cid.13177
  14. Int J Dermatol. 2023 Jan 25.
    A bibliometric analysis of hidradenitis suppurativa literature over the past 50 years.
    Galia Peles, Amir Horev.
       BACKGROUND: We aimed to describe the existing literature on hidradenitis suppurative (HS) in the last 50 years and the key processes made over time.
    METHODS: On July 27, 2022, we searched for HS studies published in the last 50 years (from 1972 to 2022) using Web of Science. The search was made using the keywords "Hidradenitis Suppurativa" and "Acne Inversa." The data are subdivided according to publications and citations rate, country, publication year, journal and impact factor, keywords analysis of top 100 cited papers study design, and pediatric versus adults.
    RESULTS: In total, 5072 documents were retrieved. The annual number of HS publications has increased over the years. The manuscript with the highest citation number was by Zouboulis et al., a total of 552 citations from 2015. The manuscript with the highest citation rate per year was by Mantovani et al., with a citation rate of 70.7/year. According to keywords analysis among the top 100 cited papers, most of the articles focused on management, followed by the pathogenesis of HS. Only 805 out of 5072 (15.8%) HS articles described the disease among children.
    CONCLUSIONS: In the current analysis, we shed light on HS's transformations over the last 50 years. In addition, we described the 100 top cited papers and other essential characteristics not examined before, such as HS research in children, gender bias research, specific pharmacological therapy with keyword analysis, comorbidities, preventative care, and publications per country after controlling for population.
    DOI:  https://doi.org/10.1111/ijd.16585
  15. Front Oncol. 2022 ;12 1024179
    Research landscape and trends of melanoma immunotherapy: A bibliometric analysis.
    Yanhao Liu, Lan Yu, Yanjiao Liang, Xi Cheng, Shu Jiang, Haiming Yu, Zhen Zhang, Linlin Lu, Baozhen Qu, Yuxian Chen, Xiaotao Zhang.
       Background: Immunotherapy for lung cancer has been a hot research area for years. This bibliometric analysis was intended to present research trends on melanoma immunotherapy.
    Method: On April 1, 2022, the authors identified 2,109 papers on melanoma immunotherapy using the Web of Science and extracted their general information and the total number of citations. The authors then conducted a bibliometric analysis to present the research landscape, clarify the research trends, and determine the most cited papers (top-papers) as well as major journals on melanoma immunotherapy. Subsequently, recent research hotspots were identified by analyzing the latest articles in major journals.
    Results: The total and median number of citations of these 2,109 papers on melanoma immunotherapy was 137,686 and 11, respectively. "Improved survival with ipilimumab in patients with metastatic melanoma" by Hodi et al. was the most cited paper (9,824 citations). Among the journals, the top-paper number (16), average citations per paper (2,510.7), and top-papers rate (100%) of New England Journal of Medicine were the highest. Corresponding authors represented the USA took part in most articles (784). Since 2016, the hottest research area has changed from CTLA-4 to PD-1.
    Conclusions: This bibliometric analysis comprehensively and quantitatively presents the research trends and hotspots based on 2,109 relevant publications, and further suggests future research directions. The researchers can benefit in selecting journals and in finding potential collaborators. This study can help researchers gain a comprehensive impression of the research landscape, historical development, and current hotspots in melanoma immunotherapy and can provide inspiration for future research.
    Keywords:  CTLA-4; PD1/PDL1; adoptive cell therapy; bibliometric analysis; clinical trials; immunotherapy; melanoma; tumor mutation burden
    DOI:  https://doi.org/10.3389/fonc.2022.1024179
  16. Front Endocrinol (Lausanne). 2022 ;13 1027945
    Global trends in polycystic ovary syndrome research: A 10-year bibliometric analysis.
    Na Shi, Hong-Bo Ma.
       Background: Polycystic ovary syndrome (PCOS) is one of the most common reproductive metabolic disorders in women, significantly affecting the biological functionalities of ovaries. This disease has garnered enormous interest from researchers. However, there is a lack of a comprehensive research concerning assessing the current status and future trends in PCOS field. This study uses bibliometric tools to comprehensively analyze the PCOS-related research progress based on the literature in the past decade.
    Methods: The reported PCOS literature in the past decade is downloaded from the Web of Science database. The bibliometric software is applied to analyze the co-authorship, co-citation, and co-occurrence status.
    Results: A total of 9936 publications imported into bibliometric tools for analysis show a sharp increase in the annual citations. The USA is dominant in terms of contribution in the field of PCOS, while China is making a significant contribution to the advancement of this field. Monash University is the most prolific institution with the highest H-index value. The contribution of University of Adelaide must be acknowledged. Legro RS and Teede HJ are the most active and influential authors in recent times, while Azziz R is the most contributed pioneer in this field. The Journal of Clinical Endocrinology & Metabolism is the most active journal with the highest number of publications and citations. The pathogenesis of PCOS had been a long-term forefront of research. In recent years, the health management in PCOS prevention and long-term complications was attracting more and more attention. The keywords like "gut microbiota", "microRNAs", "apoptosis", "Myo-inositol", "TNF-alpha", "androgen receptor", and "Vitamin D-deficient" are considered the latest research topics.
    Conclusion: The study comprehensively analyzes the current status and global trends in the PCOS field, providing a significant reference for researchers to explore this field effectively.
    Keywords:  bibliometrics; current status; global research trends; polycystic ovary syndrome; research hotspots
    DOI:  https://doi.org/10.3389/fendo.2022.1027945
  17. Front Cell Infect Microbiol. 2022 ;12 1027448
    Research trends on the relationship between gut microbiota and colorectal cancer: A bibliometric analysis.
    Weigen Wu, Yaobin Ouyang, Pan Zheng, Xinbo Xu, Cong He, Chuan Xie, Junbo Hong, Nonghua Lu, Yin Zhu, Nianshuang Li.
       Background: Colorectal cancer (CRC)is the third most common cancer in the world and the second leading cause of cancer-related deaths, and over the past two decades, many of these researchers have provided a substantial amount of important information on the role of gut microbes in the development and progression of CRC. A causal relationship between the presence of specific microorganisms and CRC development has also been validated. Although a large number of papers related to this area have been published, no bibliometric study has been conducted to review the current state of research in this area and to highlight the research trends and hotspots in this area. This study aims to analyze the current status and future research trends of gut microbiota and CRC through bibliometric analysis.
    Methods: Publications from 2001 to 2022 were retrieved from the Web of Science Core Collection database and screened according to inclusion criteria. VOSviewer and CiteSpace software were used to visualize the research trends in this field, including the analysis of title, country, institution, author, number of publications, year of publication, number of citations, journal, and H-index.
    Results: A total of 863 studies were eventually identified, and the articles retrieved were cited an average of 44.85 times each. The number of publications on this topic has been increased steadily since 2011. China and the USA have made the largest contribution in the field. FRONTIERS IN MICROBIOLOGY is the top productive journal with 26 papers, and Gut journal has the highest average citation (167.23). Shanghai Jiao Tong University is the most contributive institution. Professor Yu J, Sung, Joseph J. Y and Fang JY are the most productive authors in this field. Keyword co-occurrence analysis showed that the terms of "Gut Microbiota", "Colorectal Cancer", "Inflammation", "Probiotic" and "Fusobacterium Nucleatum" were the most frequent, which revealed the research hotpots and trends in this field.
    Conclusions: There has been a growing number of publications over the past two decades according to the global trends. China and the USA still maintained the leading position in this field. However, collaboration between institutions needs to be strengthened. It's commended to pay attention to the latest hotspots, such as "F. nucleatum" and "probiotics". This bibliometric analysis evaluates the scope and trends of gut microbiota and CRC, providing a useful perspective on current research and future directions for studying the link between the gut microbiota and CRC.
    Keywords:  bibliometric analysis; colorectal cancer; gut microbiota; hot spots; research trends
    DOI:  https://doi.org/10.3389/fcimb.2022.1027448
  18. Front Public Health. 2022 ;10 1075659
    A global bibliometric analysis on Kawasaki disease research over the last 5 years (2017-2021).
    Weifu Tan, Liao Jing, Yunxiao Wang, Wei Li.
       Background: Kawasaki disease (KD) is a systemic vasculitis of unknown etiology that mainly affects children. We aim to conduct a bibliometric analysis to explore the latest research hotspots and trends of KD.
    Method: By using the keywords "Kawasaki disease," "Kawasaki syndrome", and "Mucocutaneous Lymph Node Syndrome," the Web of Science (WOS) and Scopus databases were searched for publications related to KD from 2017 to 2021. Author, country and journal submissions were classified and evaluated using Biblioshiny software (using R language). VOSviewer (version 1.6.18) was used to visualize the relevant network relationships.
    Result: According to the search strategy, 5,848 and 6,804 KD studies were published in WOS and Scopus, respectively. The results showed an overall increasing trend in the number of publications and citations during the study period. The three most influential institutions in the WOS were St. Marianna University, Kawasaki Medical School and The University of Tokyo in Japan, while in Scopus, Harvard Medical School, University of California and Tehran University of Medical Sciences were the most influential institutions. The most influential authors of the two databases are Goodman SG, Kazunori Kataoka, and Takeshi Kimura of the WOS and Marx Nikolau and Wang Y, Burns JC, and Newburger JW of the Scopus, respectively. And Scientific Reports and Frontiers in Pediatrics were the most critical journals. The most cited documents were the WOS document by McCrindle et al. and the Scopus document by Benjamin et al. published in 2017, while the keywords in the last few years were focused on "COVID-19," "multisystem inflammatory syndrome," and "pandemic."
    Conclusion: This bibliometric analysis summarizes for the first time the research progress in KD (2017-2021), providing a qualitative and quantitative assessment of KD research bibliometric information. In the field, researchers mainly from Japan and USA are dominant, followed by China. It is recommended to pay close attention to the latest hot spots, such as "COVID-19" and "multisystem inflammatory syndrome." These results provide a more intuitive and convenient way for researchers to obtain the latest information on KD.
    Keywords:  COVID-19; Kawasaki disease; Scopus; Web of Science; bibliometric analysis
    DOI:  https://doi.org/10.3389/fpubh.2022.1075659
  19. Front Mol Neurosci. 2022 ;15 1022463
    Research hotspots and trends in visceral pain research: A global comprehensive bibliometric analysis.
    Le Guan, Yang Liu, Bin Wu, Aiqin Chen, Wucheng Tao, Chun Lin.
       Background: Visceral pain is a complex and heterogeneous disorder that is considered more prominent compared to somatic pain, due to its multiple and complex causes and accompanying emotional and mood disorders. Research has become increasingly extensive over the years, but a bibliometric analysis of this field is lacking. The aim of this study was to analyze global research trends in visceral pain over the past 40 years through visual analysis.
    Methods: We conducted a comprehensive search of the literature from January 1981 to December 2021 using the Web of Science core database. The medical subject term 'visceral pain' was searched. We used CiteSpace and VOSviewer for bibliometric analysis and network visualization, including top-ranked authors, keywords, research collaborations, and literature co-occurrence network analysis.
    Results: A total of 5,047 articles were included in the analysis. The number of articles on visceral pain has continued to grow steadily over the past 40 years. The United States (1,716 articles), University of California (159 articles), and Neurogastroenterology and Motility (276 articles) were the country, institution, and journal with the most publications, respectively. Keyword analysis showed that inflammation, visceral hypersensitivity, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), anxiety, and quality of life were the research trends and priorities in this research field.
    Conclusion: Visceral pain-related research has received increasing attention in recent decades. However, there are still many unresolved issues in the field of visceral pain, such as the specific molecular mechanisms and clinical treatments between visceral pain and inflammation, IBD, IBS, anxiety, and quality of life, which may require further exploration based on modern scientific and technological means and more basic research, especially for the therapeutic targets of visceral pain, which may become a hot spot for future research and provide guidance for the treatment of clinical diseases related to visceral pain.
    Keywords:  anxiety; bibliometric analysis; inflammation; quality of life; visceral pain
    DOI:  https://doi.org/10.3389/fnmol.2022.1022463
  20. Front Bioeng Biotechnol. 2022 ;10 1099616
    Knowledge mapping concerning applications of nanocomposite hydrogels for drug delivery: A bibliometric and visualized study (2003-2022).
    Hao Wang, Hongxun Fu, Yefan Fu, Lin Jiang, Liye Wang, Haibin Tong, Zuoxu Xie, Peng Huang, Meiyan Sun.
      Background: Nanocomposite Hydrogels (NHs) are 3D molecular networks formed by physically or covalently crosslinking polymer with nanoparticles or nanostructures, which are particularly suitable for serving as carriers for drug delivery systems. Many articles pertaining to the applications of Nanocomposite Hydrogels for drug delivery have been published, however, the use of bibliometric and visualized analysis in this area remains unstudied. The purpose of this bibliometric study intended to comprehensively analyze the knowledge domain, research hotspots and frontiers associated with the applications of Nanocomposite Hydrogels for drug delivery. Methods: We identified and retrieved the publications concerning the applications of NHs for drug delivery between 2003 and 2022 from Web of Science Core Collection Bibliometric and visualized analysis was utilized in this investigative study. Results: 631 articles meeting the inclusion criteria were identified and retrieved from WoSCC. Among those, 2,233 authors worldwide contributed in the studies, accompanied by an average annual article increase of 24.67%. The articles were co-authored by 764 institutions from 52 countries/regions, and China published the most, followed by Iran and the United States. Five institutions published more than 40 papers, namely Univ Tabriz (n = 79), Tabriz Univ Med Sci (n = 70), Islamic Azad Univ (n = 49), Payame Noor Univ (n = 42) and Texas A&M Univ (n = 41). The articles were published in 198 journals, among which the International Journal of Biological Macromolecules (n = 53) published the most articles, followed by Carbohydrate Polymers (n = 24) and ACS Applied Materials and Interfaces (n = 22). The top three journals most locally cited were Carbohydrate Polymers, Biomaterials and Advanced materials. The most productive author was Namazi H (29 articles), followed by Bardajee G (15 articles) and Zhang J (11 articles) and the researchers who worked closely with other ones usually published more papers. "Doxorubicin," "antibacterial" and "responsive hydrogels" represent the current research hotspots in this field and "cancer therapy" was a rising research topic in recent years. "(cancer) therapeutics" and "bioadhesive" represent the current research frontiers. Conclusion: This bibliometric and visualized analysis offered an investigative study and comprehensive understanding of publications regarding the applications of Nanocomposite Hydrogels for drug delivery from 2003 to 2022. The outcome of this study would provide insights for researchers in the field of Nanocomposite Hydrogels applications for drug delivery.
    Keywords:  bibliometrics; bibliometrix; citespace; drug delivery; knowledge mapping; nanocomposite hydrogels
    DOI:  https://doi.org/10.3389/fbioe.2022.1099616
  21. Front Med (Lausanne). 2022 ;9 1088083
    Researching trends in pemphigoid diseases: A bibliometric study of the top 100 most cited publications.
    Shih-Cheng Huang, Tsu-Man Chiu, Chien-Ying Lee, Hui-Chin Chang, Wen-Jun Wu, Shuo-Yan Gau.
       Background: In the field of autoimmune and inflammatory disorders, different approaches were applied to provide information regarding disease activity, comorbidities, epidemiological reports and risk factors. However, no previous studies had thoroughly analyzed the research trend in the field, and the bibliometric analysis focusing on pemphigoid diseases was available. The objective of the current study was to evaluate the current research trend in the field.
    Methods: A search has been conducted for the Web of Science database based on various subcategories of pemphigoid diseases. Detailed information including articles' publication types, Author information, citation, and publication information was attained for further analysis.
    Results: Within the 6,995 studies, the top 100 most-cited articles were extracted for analysis. Among the top 100 studies, 70% of the studies focused on bullous pemphigoid. More than 60% of the top 100 studies were studies with original data. Furthermore, 30% of the studies were guidelines and narrative reviews. For the issues primarily focused on, most of the high-impact studies described the molecular mechanism of pemphigoid diseases (26%), managements (19%), risk factors of pemphigoid diseases (17%). Additionally, some other studies provided general review or discussed about the issue of epidemiology, diagnosis/definition, comorbidities and clinical characteristics of pemphigoid diseases.
    Conclusion: This comprehensive bibliographic study of pemphigoid diseases provided an overview of current research focuses in the field. Topics such as disease management, molecular mechanism of pathogenesis, and drug-inducing pemphigoid diseases were highly mentioned in the most-cited studies. For researchers and clinicians, the researching trend and study focus in the top-100 cited studies could serve as a potential reference for future investigation and patient management.
    Keywords:  autoimmune; bibliometric analysis; dermatology; immunology; pemphigoid diseases
    DOI:  https://doi.org/10.3389/fmed.2022.1088083
  22. Heliyon. 2023 Jan;9(1): e12896
    Health literacy in childhood and adolescence. A bibliometric analysis of scientific publications and professionals' involvement.
    Nerea Santafé-Madueño, Anabel Ramos-Pla, Laia Selva-Pareja, Maria Barcenilla-Guitard, Anna Espart.
       Background: Health Literacy (HL) is a powerful tool to empower children and adolescents in their own health. School nurses are the professionals who, with their expertise in health promotion and education, can facilitate this literacy throughout the educational process.
    Purpose: To analyze the scientific production in HL in childhood and adolescence in the last two decades, and to determine the involvement of professionals in this field, with emphasis on nursing professionals.
    Methods: A bibliometric analysis of the scientific literature (from 2000 to 2021) of articles retrieved from the Web of Science database was carried out. Original articles in all languages were considered as inclusion criteria. Bibliometrix 3.1.4 package from RStudio and VOSviewer were used to analyze publications and explain main results about citations, authors, countries, keywords trends, evolution, clusters of related terms, and professionals' involvement.
    Results: A total of 2032 articles were included in the analysis. The results of the analysis showed that both publications and citations increased substantially since 2014. The most prolific authors in this field are not the most cited so far. The countries that published the most during the period evaluated were the United States, Australia and Canada. The keyword clusters identified in this scientometric study made it possible to determine hotspots in the study of HL in childhood and adolescence, with "mental health" being one of the main terms identified. There are different health-related professionals who are publishing in this field; in spite of this, nurses are not visible as authors in the publications.
    Conclusion: The scientific literature on HL in childhood and adolescence is a growing field in which different professionals are involved. Despite the increase in the number of publications, and despite the role that nurses play in schools regarding HL, their presence in scientific production is practically nonexistent.
    Keywords:  Adolescence; Bibliometrics; Childhood; Health Literacy; Nursing
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e12896
  23. Medicine (Baltimore). 2023 Jan 27. 102(4): e32780
    Knowledge domain and dynamic patterns in multimodal molecular imaging from 2012 to 2021: A visual bibliometric analysis.
    Zhe Du, Tianbing Wang.
      Multimodal molecular imaging technologies have been widely used to optimize medical research and clinical practice. Bibliometric analysis was performed to identify global research trends, hot spots, and scientific frontiers of multimodal molecular imaging technology from 2012 to 2021. The articles and reviews related to multimodal molecular imaging were retrieved from the Web of Science Core Collection. A bibliometric study was performed using CiteSpace and VOSviewer. A total of 4169 articles and reviews from 2012 to 2021 were analyzed. An increasing trend in the number of articles on multimodal molecular imaging technology was observed. These publications mainly come from 417 institutions in 92 countries, led by the USA and China. K. Bailey Freund published the most papers amongst the publications, while R.F. Spaide had the most co-citations. A dual map overlay of the literature shows that most publications were specialized in physics/materials/chemistry, and molecular/biology/immunology. Synergistic therapy in cancer, advanced nanotechnology, and multimodal imaging in ophthalmology are new trends and developing areas of interest. A global bibliometric and visualization analysis was used to comprehensively review the published research related to multimodal molecular imaging. This study may help in understanding the dynamic patterns of multimodal molecular imaging technology research and point out the developing areas of this field.
    DOI:  https://doi.org/10.1097/MD.0000000000032780
  24. Front Public Health. 2022 ;10 1040676
    Bibliometric and visualization analysis of research trend in mental health problems of children and adolescents during the COVID-19 pandemic.
    Zeming Guo, Yiran Zhang, Qin Liu.
       Objectives: To analyze the evolution of research on children and adolescents mental health issues during COVID-19 pandemic and discuss research hotspots and cutting-edge developments.
    Methods: The literature obtained from the web of science core collection as of June 28, 2022, was analyzed using Citespace, VOSviewer bibliometric visualization mapping software.
    Results: A total of 6,039 relevant papers were found, of which 5,594 were included in the study. The number of literatures is growing since 2020; and the country, institution, and journal publications were analyzed. The co-citation analysis shows that there are more research articles among the highly cited articles and a lack of systematic reviews that use critical thinking for review. In the cluster analysis, mental health and life change were the most representative. The timeline view of the keywords shows that Online learning (#0), Public health (#1), and Mental health (#2) are the three largest clusters and shows the change over time.
    Conclusion: This study helped analyze the mental health of children and adolescents during the COVID-19 pandemic and identified hot trends and shortcomings, which are important references for the theoretical basis of future research and decision making and technical guidance for systematic reviews.
    Keywords:  COVID-19; Citespace; adolescent; bibliometric analysis; children; mental health
    DOI:  https://doi.org/10.3389/fpubh.2022.1040676
  25. Heliyon. 2023 Jan;9(1): e12765
    Research trends, developments, and future perspectives in brand attitude: A bibliometric analysis utilizing the Scopus database (1944-2021).
    Alharthi Rami Hashem E, Nor Zafir Md Salleh, Mazilah Abdullah, Adnan Ali, Faisal Faisal, Roshazlizawati Mohd Nor.
      Brand attitude has been the primary concern for corporation sustainability for a long. Studies have focused on various attributes concerning brand attitude comprising of many research articles. This study focuses on bibliometric analysis of brand attitude examining 1497 documents published for the years 1944-2021. The purpose of this study is to examine historic research trends, developments, and future conduits based on co-authorship and co-occurrence analysis using VOSviewer. The study highlights the most prolific articles containing the most productive authors and their affiliations, keywords, and influential journals, along with future research trends. The result shows that the number of publications follows a very slow trail until 2008, mildly until 2012, following which the cumulative growth in publication increased manifold. Further, results show that researchers from the United States, South Korea, and Taiwan extended many efforts to the global knowledge of literature leading other countries. The emerging hotspot keywords analysis suggests that brand avoidance, subtle, brand betrayal, consumer ethnocentrism, environmental sustainability and policy, brand activism, brand authenticity, consumer brand engagement, and brand competence are the key areas that attract researchers' attention policymakers as future research boulevards. In the case of consumers' brand attitudes, there is a scarcity of studies that investigated the consumers' implicit and explicit brand attitudes.
    Keywords:  Bibliometric analysis; Brand attitude; Explicit brand attitude; Implicit brand attitude; Scientometrics analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e12765
  26. Front Pharmacol. 2022 ;13 1009025
    Bibliometric and visualized analysis of sodium-Glucose cotransporter 2 inhibitors.
    He Sun, Zhongqing Wang, Yuxi Wang, Haichuan Rong, Danyang Wang, Xiangnian Liu, Ke Jin, Zhicheng Sun, Qiuling Fan.
      Background: Sodium-glucose cotransporter 2 inhibitors have proved to be extremely effective and reliable in reducing hyperglycemia, and have also been used for the treatment of cardiovascular and renal disease in patients with or without type 2 diabetes. Thousands of research articles on SGLT2 inhibitors have been published in the past, but few bibliometric analyses have systematically been studied this field. We aimed to visualize the global research hotspots and trends of SGLT2 inhibitors using a bibliometric analysis to provide new evidence and ideas for researchers and clinicians in this field. Methods: We retrieved publications from Science Citation Index Expanded of Web of Science Core Collection in 2004-2022 on 1 July 2022. Microsoft Excel, CiteSpace and VOSviewer were employed to collect publication data, analyze publication trends, and visualize relevant results. Results: We identified 4,419 original research articles on SGLT2 inhibitors published between 2004 and the first half of 2022. Global SGLT2 inhibitors-related research increased rapidly from 2004 to 2022, especially recently. United States made the greatest contribution to the topic, with (1,629, 36.86%) publications and citations (88,892). AstraZeneca was the most prolific institutions (272, 6.16%). Heerspink HJL published the most related articles (98), whereas Zinman B was cited the most frequently (1,784 citations). Diabetes Obesity and Metabolism was the journal with the most studies (406, 9.19%), and The New England Journal of Medicine was the most commonly cited journal (11,617 citations), with nine of the top 10 co-cited references published in this journal. The emerging keywords "heart failure," "diabetic cardiomyopathy," "ejection fraction," "mortality," "biomarker," "fibrosis," "ampk," and "guideline" appeared the most recently as research frontiers. Conclusion: United States is the leader in SGLT2 inhibitor research. Recently, the research on SGLT2 inhibitors has focused on clinical trials, related mechanisms, and therapy. In the future, the research on SGLT2 inhibitors will delve into molecular mechanisms, especially those related to fibrosis and AMPK, revealing the link between SGLT2 inhibitors and heart failure and diabetic cardiomyopathy will be the next research hotspot.
    Keywords:  bibliometric; co-occurrence analysis; diabetic cardiomyopathy; heart failure; sodium—glucose cotransporter 2 inhibitor; visualization
    DOI:  https://doi.org/10.3389/fphar.2022.1009025
  27. Front Microbiol. 2022 ;13 1067803
    Global trends and hotspots of phage therapy for bacterial infection: A bibliometric visualized analysis from 2001 to 2021.
    Zulipikaer Maimaiti, Zhuo Li, Chi Xu, Jiying Chen, Wei Chai.
       Background: Antibiotic resistance is one of the main global threats to human health, and just the development of new antimicrobial medications is not enough to solve the crisis. Phage therapy (PT), a safe and effective treatment method, has reignited the interest of researchers due to its efficacy in the clinical treatment of drug-resistant bacterial infections. There is, however, no bibliometric analysis of the overall trends on this topic. Therefore, this study aims to provide an overview of the current state of development and research in this area.
    Methods: We extracted all relevant publications from the Web of Science Core Collection (WoSCC) database between 2001 and 2021. We performed bibliometric analysis and visualization using CiteSpace, VOS viewer, and R software. Annual trends of publications, countries/regions distributions, institutions, funding agencies, co-cited journals, author contributions, core journals, references, and keywords were analyzed.
    Results: A total of 6,538 papers were enrolled in this study, including 5,364 articles and 1,174 reviews. Publications have increased drastically from 61 in 2001 to 937 in 2021, with 3,659 articles published in the last 5 years. North America, Western Europe, and East Asia were significant contributor regions. The United States, China, and the United Kingdom were the most productive countries. The Polish Academy of Sciences was the most contributive institution. Frontiers in Microbiology and Applied and Environmental Microbiology were the most productive and co-cited journals. A. Gorski and R. Lavigne published most articles in this field, while V. A. Fischetti was the author with the most cited. Regarding keywords, research focuses include phage biology, phage against clinically important pathogens, phage lysis proteins, phage therapy, biofilm-related research, and recent clinical applications.
    Conclusion: Phage therapy is a potential strategy for combating antibiotic resistance, and it will provide us with an alternative therapeutic option for bacterial infection. According to global trends, the scientific output of PT in bacterial infections is increasing, with developed countries such as the United States leading the way in this area. Although the safety and efficacy of PT have been proven, more clinical trials on the phages against infectious diseases caused by various pathogens are still needed.
    Keywords:  bacterial infection; bibliometrics; hotspot; phage therapy; research trends
    DOI:  https://doi.org/10.3389/fmicb.2022.1067803
  28. Front Surg. 2022 ;9 1048454
    Global research trends in catheter ablation and surgical treatment of atrial fibrillation: A bibliometric analysis and science mapping.
    Xiang Gao, Kai Liu, Xinke Zhao, Xinfang Lv, Xue Wu, Chunzhen Ren, Qilin Chen, Yingdong Li.
       Introduction: To evaluate the global research results of the catheter ablation and surgical treatment of atrial fibrillation in the past 40 years by bibliometrics, and to explore the hotspots and prospects for future development.
    Methods: Relevant literatures were selected from the Web of Science Core Collection. VOSviewer 1.6.17, SciMAT 1.1.04, and CiteSpace 5.8.R1 were used to analyze the data objectively, deeply and comprehensively.
    Results: As of July 14, 2021, 11,437 studies for the catheter ablation and surgical treatment of atrial fibrillation have been identified from 1980 to 2021. The Journal of Cardiovascular Electrophysiology and Circulation respectively ranked first in terms of the number of publications and the number of co-citations. A total of 6,631 institutions from 90 countries participated in the study, with USA leading the way with 3,789 documents. Cryoablation, atrial fibrosis, substrate modification, minimally invasive and access surgery will still be the research focus and frontier in the next few years.
    Conclusions: The publication information for the catheter ablation and surgical treatment of atrial fibrillation were reviewed, including country, institution, author, journal publications, and so on. Developed countries had the advantage in this research areas, and cooperation with low-income countries should be improved. The former research hotspots in the field of catheter ablation and surgical treatment of atrial fibrillation were analyzed, and the future research direction was predicted.
    Keywords:  atrial fibrillation; bibliometric analysis; catheter ablation; citation analysis; science mapping analysis; surgical treatment
    DOI:  https://doi.org/10.3389/fsurg.2022.1048454
  29. Front Aging Neurosci. 2022 ;14 1057214
    Knowledge domains and emerging trends of microglia research from 2002 to 2021: A bibliometric analysis and visualization study.
    Guangjie Liu, Tianhua Li, Anming Yang, Xin Zhang, Songtao Qi, Wenfeng Feng.
       Background: Microglia have been identified for a century. In this period, their ontogeny and functions have come to light thanks to the tireless efforts of scientists. However, numerous documents are being produced, making it challenging for scholars, especially those new to the field, to understand them thoroughly. Therefore, having a reliable method for quickly grasping a field is crucial.
    Methods: We searched and downloaded articles from the Web of Science Core Collection with "microglia" or "microglial" in the title from 2002 to 2021. Eventually, 12,813 articles were located and, using CiteSpace and VOSviewer, the fundamental data, knowledge domains, hot spots, and emerging trends, as well as the influential literature in the field of microglia research, were analyzed.
    Results: Following 2011, microglia publications grew significantly. The two prominent journals are Glia and J Neuroinflamm. The United States and Germany dominated the microglia study. The primary research institutions are Harvard Univ and Univ Freiburg, and the leading authors are Prinz Marco and Kettenmann Helmut. The knowledge domains of microglia include eight directions, namely neuroinflammation, lipopolysaccharide, aging, neuropathic pain, macrophages, Alzheimer's disease, retina, and apoptosis. Microglial phenotype is the focus of research; while RNA-seq, exosome, and glycolysis are emerging topics, a microglial-specific marker is still a hard stone. We also identified 19 influential articles that contributed to the study of microglial origin (Mildner A 2007; Ginhoux F 2010), identity (Butovsky O 2014), homeostasis (Cardona AE 2006; Elmore MRP 2014); microglial function such as surveillance (Nimmerjahn A 2005), movement (Davalos D 2005; Haynes SE 2006), phagocytosis (Simard AR 2006), and synapse pruning (Wake H 2009; Paolicelli RC 2011; Schafer DP 2012; Parkhurst CN 2013); and microglial state/phenotype associated with disease (Keren-Shaul H 2017), as well as 5 review articles represented by Kettenmann H 2011.
    Conclusion: Using bibliometrics, we have investigated the fundamental data, knowledge structure, and dynamic evolution of microglia research over the previous 20 years. We hope this study can provide some inspiration and a reference for researchers studying microglia in neuroscience.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; knowledge domain; microglia
    DOI:  https://doi.org/10.3389/fnagi.2022.1057214
  30. Front Neurol. 2022 ;13 1085684
    Global research hot spot and trends in tinnitus treatment between 2000 and 2021: A bibliometric and visualized study.
    Tao Ye, Kefan Chen, Dongyang Li, Kailong Yin, Yuan Li, Jin Long, Lian Hui.
       Background: In the 21st century, the prevalence of tinnitus is increasing, impacting approximately one in five people. It is a very complicated condition that significantly affects quality of life. Despite the availability of hundreds of tinnitus treatment options, none are very successful. In light of this, there has been a steady increase in studies on tinnitus treatments in the recent past. To comprehend them better, this study used bibliometric approaches to analyze and summarize 21st century scientific research accomplishments in tinnitus treatment.
    Methods: The Web of Science Core Collection (WoSCC) was searched for papers that had been published and related to the treatment of tinnitus. VOSviewer, CiteSpace, R, and Tableau software programs were used to conduct bibliometric studies. To evaluate and visualize the results.
    Results: 2,933 publications on tinnitus treatment were found in 74 countries. Between 2000 and 2021, publications increased steadily. Otolaryngology-Head & Neck Surgery had the highest impact factor, whereas Otology & Neurotology had the most magazines and the highest h, g, and m index. Langguth B was the most prolific author in terms of productivity during the past 21 years. Numerous eminent authors and organizations from multiple nations collaborated. With 626 papers, the United States of America (USA) contributed the most to this field, making them the leading contributor. Neuroplasticity, sound therapy, and cognitive behavioral therapy (CBT) have attracted the attention of researchers, leading to the development of innovative diagnostic and treatment strategies for tinnitus.
    Conclusion: This bibliometric study provides a comprehensive analysis of worldwide publications, cooperation, and research hotspots in tinnitus therapy, revealing the present status of research on this issue and guiding tinnitus treatment research in the coming years.
    Keywords:  bibliometric analysis; management; research frontiers; tinnitus; visualized maps
    DOI:  https://doi.org/10.3389/fneur.2022.1085684
  31. Front Oncol. 2022 ;12 1075974
    Artificial intelligence applicated in gastric cancer: A bibliometric and visual analysis via CiteSpace.
    Guoyang Zhang, Jingjing Song, Zongfeng Feng, Wentao Zhao, Pan Huang, Li Liu, Yang Zhang, Xufeng Su, Yukang Wu, Yi Cao, Zhengrong Li, Zhigang Jie.
       Objective: This study aimed to analyze and visualize the current research focus, research frontiers, evolutionary processes, and trends of artificial intelligence (AI) in the field of gastric cancer using a bibliometric analysis.
    Methods: The Web of Science Core Collection database was selected as the data source for this study to retrieve and obtain articles and reviews related to AI in gastric cancer. All the information extracted from the articles was imported to CiteSpace to conduct the bibliometric and knowledge map analysis, allowing us to clearly visualize the research hotspots and trends in this field.
    Results: A total of 183 articles published between 2017 and 2022 were included, contributed by 201 authors from 33 countries/regions. Among them, China (47.54%), Japan (21.86%), and the USA (13.11%) have made outstanding contributions in this field, accounting fsor 82.51% of the total publications. The primary research institutions were Wuhan University, Tokyo University, and Tada Tomohiro Inst Gastroenterol and Proctol. Tada (n = 12) and Hirasawa (n = 90) were ranked first in the top 10 authors and co-cited authors, respectively. Gastrointestinal Endoscopy (21 publications; IF 2022, 9.189; Q1) was the most published journal, while Gastric Cancer (133 citations; IF 2022, 8.171; Q1) was the most co-cited journal. Nevertheless, the cooperation between different countries and institutions should be further strengthened. The most common keywords were AI, gastric cancer, and convolutional neural network. The "deep-learning algorithm" started to burst in 2020 and continues till now, which indicated that this research topic has attracted continuous attention in recent years and would be the trend of research on AI application in GC.
    Conclusions: Research related to AI in gastric cancer is increasing exponentially. Current research hotspots focus on the application of AI in gastric cancer, represented by convolutional neural networks and deep learning, in diagnosis and differential diagnosis and staging. Considering the great potential and clinical application prospects, the related area of AI applications in gastric cancer will remain a research hotspot in the future.
    Keywords:  CiteSpace; Web of Science; artificial intelligence; bibliometric analysis; gastric cancer; research trends
    DOI:  https://doi.org/10.3389/fonc.2022.1075974
  32. Front Pharmacol. 2022 ;13 1048211
    Mapping knowledge landscapes and emerging trends of sonodynamic therapy: A bibliometric and visualized study.
    Zhenjiang Wu, Kunming Cheng, Zefeng Shen, Yanqiu Lu, Hongtao Wang, Guolei Wang, Yulin Wang, Weiguang Yang, Zaijie Sun, Qiang Guo, Haiyang Wu.
      Background: Ultrasound-triggered sonodynamic therapy (SDT), as a non-invasive approach, has attracted considerable attention in a wide variety of malignant tumors and other diseases. Over the past 2 decades, the number of scientific publications on SDT has increased rapidly. However, there is still a lack of one comprehensive report that summarizes the global research trends and knowledge landscapes in the field of SDT in detail. Thus, we performed a bibliometric analysis on SDT from 2000 to 2021 to track the current hotspots and highlight future directions. Methods: We collected publications on SDT research from the Web of Science Core Collection database. The annual number of publications and citations, major contributors, popular journals, international collaborations, co-cited references and co-occurrence keywords were analyzed and visualized with CiteSpace, VOSviewer, and R-bibliometrix. Results: A total of 701 publications were included. The annual publication output increased from 5 in 2000 to 175 in 2021, and the average growth rate was 18.4%. China was the most productive country with 463 documents (66.05%), and Harbin Medical University was the most prolific institution (N = 73). Ultrasound in Medicine and Biology published the most papers related to SDT. Materials Science, and Chemistry were the research areas receiving the most interest. All the keywords were divided into four different clusters including studies on mechanisms, studies on drug delivery and nanoparticles, studies on cancer therapy, as well as studies on ultrasound and sonosensitizers. In addition to nanomaterials-related studies including nanoparticles, mesoporous silica nanoparticles, nanosheets, liposomes, microbubble and TiO2 nanoparticle, the following research directions such as immunogenic cell death, metal-organic framework, photothermal therapy, hypoxia, tumor microenvironment, chemodynamic therapy, combination therapy, tumor resistance, intensity focused ultrasound, drug delivery, and Staphylococcus aureus also deserve further attention and may continue to explode in the future. Conclusion: SDT has a bright future in the field of cancer treatment, and nanomaterials have increasingly influenced the SDT field with the development of nano-technology. Overall, this comprehensive bibliometric study was the first attempt to analyze the field of SDT, which could provide valuable references for later researchers to better understand the global research trends, hotspots and frontiers in this domain.
    Keywords:  bibliometric; cancer; data visualization; nanoparticle; sonodynamic therapy; ultrasound
    DOI:  https://doi.org/10.3389/fphar.2022.1048211
  33. Ocul Immunol Inflamm. 2023 Jan 25. 1-10
    Global Research Status Regarding Uveitis in the Last Decade.
    Ao Lu, Zhangluxi Liu, Guannan Su, Peizeng Yang.
       PURPOSE: To provide an overview on global uveitis research in the last decade in terms of countries/regions, organizations, scholars, journals, trending topics, and fundings.
    METHODS: This cross-sectional bibliometric analysis yielded 10656 uveitis publications in English for subsequent bibliometric analysis.
    RESULTS: In terms of the number of publications, the leading country/region was the USA (3007). The most productive organizations were the University College London (420). The most productive research teams were Professor Yang's group (146). A higher h-index was noted in University College London (48). Professor Rosenbaum was the first h-index holder (32). Keywords of interest includes topics such as biologics, COVID and OCT. Publications by Ocular Immunology and Inflammation (968) ranked the first position.
    CONCLUSIONS: The USA is the leading force in uveitis study. Asian countries/regions, such as China (mainland) and India, are exerting a substantial role worldwide. Trendy topics cover COVID-19, OCTA.
    Keywords:  Bibliometric analysis; big data; data mining; scientific performance; uveitis
    DOI:  https://doi.org/10.1080/09273948.2023.2170251
  34. Front Neurosci. 2022 ;16 1088448
    Bibliometric and visual analysis of cerebral revascularization from 1999 to 2022.
    Ding Zhang, Xiaoqian Li, Ni Jia, Wei Chen, Yueqiang Hu.
       Background: Cerebral revascularization is a neurosurgical procedure used to restore the cerebral collateral circulation channel. This study examines the countries, institutions, authors, journals, keywords, and references related to the disease in the field of cerebral revascularization from 1999 to 2022 from a bibliometrics perspective, evaluates the changes of knowledge structure clustering and identifies the new hot spots and new research directions in this field.
    Methods: The Web of Science Core Collection (WOSCC) database and the PICOS retrieval method were used to conduct a comprehensive search for articles and reviews pertaining to cerebral revascularization. The final filtered data were bibliometrically and visually drawn using Microsoft office 365, CiteSpace (v.6.1.R2), and VOSviewer (v.1.6.18).
    Results: From 1999 to 2022, a total of 854 articles pertaining to cerebral revascularization, which originated from 46 nations, 482 institutions, and 686 researchers, were extracted from the WOSCC database, and the number of publications in this field of study was rising. The United States held the highest proportion in the ranking analysis of countries, institutions, authors, and journals. By analyzing co-citations, the scientific organization of this field and the development status of frontier fields were realized. Cerebral revascularization, moyamoya disease, extracranial intracranial bypass, and occlusion are the current research focal points in the field of cerebral revascularization. Hyperperfusion and vascular disorder may also become a new study focus in this discipline in the near future.
    Conclusion: Using the method of bibliometrics, this study analyzed and reviewed the articles in the field of cerebral revascularization, which enabled scholars to better comprehend the dynamic process in this field and provided a foundation for future in-depth research.
    Keywords:  CiteSpace; VOSviewer; bibliometric; cerebral revascularization; visualization
    DOI:  https://doi.org/10.3389/fnins.2022.1088448
  35. Front Neurol. 2022 ;13 1026867
    A bibliometric analysis of telerehabilitation services for patients with stroke.
    Dan Wu, Haojie Zhang, Yan Leng, Kai Li, Shijue Li, Wai Leung Ambrose Lo.
       Background: Routine rehabilitation services were disrupted by the COVID-19 pandemic outbreak. Telehealth was identified as an alternative means to provide access to these services. This bibliometric study aimed to analyze the scientific literature to discover trends and topics in the potential applications of telerehabilitation for patients with stroke.
    Methods: The Web of Science electronic database was searched to retrieve relevant publications on telerehabilitation. Bibliometric data, including visual knowledge maps of authors, countries, institutions, and references, were analyzed in CiteSpace. Visualization maps were generated in VOSviewer to illustrate recurrent keywords and countries actively involved in this research area.
    Results: The analysis was performed based on 6,787 publications. The number of publications peaked between 2019 and 2021, coinciding with the years of the COVID-19 outbreak. A total of 113 countries in Europe, North America, Asia, and Oceania had at least one publication in this research field, implying global attention in this research area. Nine of the top 10 most productive countries are developed countries, indicating a potentially higher capability to implement a telerehabilitation program.
    Conclusion: The potential benefits and diversity of telerehabilitation are already highly visible from clinical studies, and further improvements in these technologies are expected to enhance functionality and accessibility for patients. More relevant research is encouraged to understand the barriers to increased adaptation of telerehabilitation services, which will finally translate into a significant therapeutic or preventive impact.
    Keywords:  bibliometric analysis; cerebral vascular accident (CVA); rehabilitation; stroke; telerehabilitation
    DOI:  https://doi.org/10.3389/fneur.2022.1026867
  36. Semin Ophthalmol. 2023 Jan 25. 1-4
    Predictors of Citations for Original Research in Ophthalmology.
    Angela S Zhu, John C Lin, Chaerim Kang, Riaz Qureshi, Roberta W Scherer, Paul B Greenberg.
      There is a dearth of literature on factors associated with citation of publications in ophthalmology. We investigated predictors of citations for original ophthalmologic research articles based on author, study, and journal characteristics. In accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA), we extracted articles that studied the leading cause of vision impairment in the United States (cataract, diabetic retinopathy, age-related macular degeneration, and glaucoma) and were published in the top fifteen ophthalmology journals with the highest impact factors that accepted original research. Descriptive statistics, one-way analysis of variance (ANOVA) tests, and negative binomial regression were used to compare citation counts based on author, study, and journal characteristics. In this study, author research productivity, journal impact factor, study funding, and location in high-income countries were predictors of increased citation in ophthalmology.
    Keywords:  citations; ophthalmology; research articles
    DOI:  https://doi.org/10.1080/08820538.2023.2168493
  37. Curr Med Res Opin. 2023 Jan 28. 1-21
    Gender differences in pulmonology and critical care authorship and editorial boards.
    Adeel Nasrullah, Alisha Sharma, Amina Hamza, Deeksha Ramanujam, Sana Shah, Shiza Virk, Aaisha Shah, Anam Javed, Ishan Garg, Lisa Saa, Akanksha Verma, Andrew Faturous, Sara Assaf, Briana DiSilvio, Abu Baker Sheikh.
       OBJECTIVE: This study aims to characterize the gender distribution of first authors, senior authors, and editorial board members across several high-impact factor journals in PCCM.
    METHODS: In this cross-sectional study, we analysed gender disparities in critical care authorship and editorial boards, based on publications from January 1, 2019 to December 31, 2021 from the top 20 high impact journals based on the Journal of Citation Reports.
    RESULTS: Among 20 journals (median impact factor of 6.66), 25% of editors-in-chief and 28.8% of editorial board members were female. From 2019 to 2021, a total of 23,994 articles were published. Female first authors and last authors made up 29.1% and 21.2% of the authorship, respectively (n = 6,637 articles).
    CONCLUSIONS: Our study demonstrates significant gender disparities in critical care authorship and editorial boards, with males predominantly filling the roles of editors in chief, editorial members, and first and senior authors. Despite this significant difference in gender distribution, there was no statistically significant correlation between authorship and editor gender.
    Keywords:  Diversity; Gender disparity; gender equity; leadership; pulmonology and critical care; women
    DOI:  https://doi.org/10.1080/03007995.2023.2174329
  38. Front Surg. 2022 ;9 1078052
    Comprehensive analysis of global research on overactive bladder: A scientometric approach.
    Lu Wang, Sheng Deng, Fanchao Meng, Lun Zhang, Zhenxing Min, Jitao Li, Jisheng Wang.
       Background: Overactive bladder, a syndrome marked by an urgent need to urinate, is a globally prevalent ailment. Human health and quality of life are seriously affected. Therefore, it is essential to investigate the current progress and trends in this field.
    Objective: No bibliometric analysis of overactive bladder has been conducted. Through the use of bibliometrics and visualization, this study intends to examine the current progress and development trend of this field.
    Methods: Global publications on overactive bladder between January 2004 and August 2022 were extracted from the Web of Science core collection database. A bibliometric and visual analysis was carried out using VOSviewer software and CiteSpace.
    Results: Over the last 20 years, publications have grown rapidly, but after 2019, they started to fall. According to the collaboration network, the United States, Univ Pittsburgh AND NEUROUROLOGY AND URODYNAMICS are the most active countries, institutes AND journals in the field, respectively. All keywords were categorized by the symbiosis analysis into four categories: experimental study, symptoms, clinical use, and quality of life. The most prevalent keyword across all clusters is "overactive bladder."
    Conclusion: Year after year, there have been more publications in the field of overactive bladder research in many countries, and there has been a deeper level of cooperation and exchange. Researchers will still be interested in overactive bladder in the future. Currently, the clinical application of the disease and the safety and effectiveness of medications are being investigated. However, radical innovation in relevant experimental technologies is a significant obstacle in this field.
    Keywords:  analysis; bibliometric; clinical research; overactive bladder; publications
    DOI:  https://doi.org/10.3389/fsurg.2022.1078052
  39. Front Cell Dev Biol. 2022 ;10 1070516
    Bibliometric analysis of scientific papers on extracellular vesicles in kidney disease published between 1999 and 2022.
    Marady Hun, Huai Wen, Phanna Han, Tharith Vun, Mingyi Zhao, Qingnan He.
      Background: In recent years, there has been an increasing interest in using extracellular vesicles (EVs) as potential therapeutic agents or natural drug delivery systems in kidney-related diseases. However, a detailed and targeted report on the current condition of extracellular vesicle research in kidney-related diseases is lacking. Therefore, this prospective study was designed to investigate the use of bibliometric analysis to comprehensively overview the current state of research and frontier trends on extracellular vesicle research in kidney-related diseases using visualization tools. Methods: The Web of Science Core Collection (WoSCC) database was searched to identify publications related to extracellular vesicle research in kidney-related diseases since 1999. Citespace, Microsoft Excel 2019, VOSviewer software, the R Bibliometrix Package, and an online platform were used to analyze related research trends to stratify the publication data and collaborations. Results: From 1 January 1999 to 26 June 2022, a total of 1,122 EV-related articles and reviews were published, and 6,486 authors from 1,432 institutions in 63 countries or regions investigated the role of extracellular vesicles in kidney-related diseases. We found that the number of articles on extracellular vesicles in kidney-related diseases increased every year. Dozens of publications were from China and the United States. China had the most number of related publications, in which the Southeast University (China) was the most active institution in all EV-related fields. Liu Bi-cheng published the most papers on extracellular vesicles, while Clotilde Théry had the most number of co-citations. Most papers were published by The International Journal of Molecular Sciences, while Kidney International was the most co-cited journal for extracellular vesicles. We found that exosome-related keywords included exosome, exosm, expression, extracellular vesicle, microRNA, microvesicle, and liquid biopsy, while disease- and pathological-related keywords included biomarker, microRNA, apoptosis, mechanism, systemic lupus erythematosus, EGFR, acute kidney injury, and chronic kidney disease. Acute kidney disease (AKI), CKD, SLE, exosome, liquid biopsy, and extracellular vesicle were the hotspot in extracellular vesicle and kidney-related diseases research. Conclusion: The field of extracellular vesicles in kidney-related disease research is rapidly growing, and its domain is likely to expand in the next decade. The findings from this comprehensive analysis of extracellular vesicles in kidney-related disease research could help investigators to set new diagnostic, therapeutic, and prognostic ideas or methods in kidney-related diseases.
    Keywords:  EVs; acute kidney disease; bibliometric analysis; chronic kidney disease; exosomes; kidney disease
    DOI:  https://doi.org/10.3389/fcell.2022.1070516
  40. Front Psychol. 2022 ;13 1019417
    Bibliometric analysis of the effects of mental fatigue on athletic performance from 2001 to 2021.
    Xiao-Xin Chen, Zhi-Guang Ji, Yi Wang, Jing Xu, Li-Yan Wang, Hong-Biao Wang.
       Aims: To explore the research hot topics and main contents in the field of the influence of mental fatigue on athletic performance, and to provide new ideas and directions for future research in this field.
    Methods: Using CiteSpace and VOSviewer visualization tool software core collection of Web of Science database to TS = ("mental fatigue" OR "mental exertion" OR "cognitive fatigue" OR "Cognitive exertion" OR "mental exhaustion" OR "mental tiredness") AND ("athletic performance" OR "technical skill*" OR "Skill*" OR "technique" OR "decision making" OR "performance") AND ("Humans") searched for the influence of mental fatigue on athletic performance from 2001 to 2021 to conduct visual analysis. Research hot topics were analyzed from the aspects of high-impact countries/regions, institutions, authors, high-frequency keywords, and mutation terms.
    Results: A total of 658 publications were identified finally, and there has been an increasing trend in the annual number of publications, with the United States ranking first in the number of publications and influence. Future research will focus on promoting the application of EEG technology as an objective indicator for assessing mental fatigue, exploring effective methods and measures for pharmacological or non-pharmacological interventions against fatigue, and focusing on the effects of mental fatigue on endurance performance, technical skills, and sports-related decision-making.
    Conclusion: The results of the present study help us understand the status of the mental fatigue and athletic performance field and its recent developments.
    Keywords:  athletic performance; bibliometric analysis; decision-making; mental fatigue; technical skill
    DOI:  https://doi.org/10.3389/fpsyg.2022.1019417
  41. Plast Reconstr Surg Glob Open. 2023 Jan;11(1): e4711
    Nationwide Bibliometric Analysis of Integrated Plastic Surgery Program Directors.
    Michelle Y Seu, Shooka Esmaeeli, Aaron L Wiegmann, Jennifer Akin, Taylor Jaraczewski, Farnaz Dadrass, Thomas Q Xu, Amir H Dorafshar, Deana Shenaq.
      Studies have linked bibliometric indices with the academic level of plastic surgeons, but this relationship has not been explored with residency program directors (PDs). As teachers of the next generation, PDs' academic performance is an important component of residency program success. We sought to identify distinguishing characteristics of integrated plastic surgery programs, focusing on their PD bibliometric indices.
    Methods: We identified plastic surgery programs based on 2021 Doximity reputation and research output rankings, respectively, and then divided them into four quartiles (Q1-Q4). PD academic history and bibliometric indices (h-index, the number of publications, and citations) were collected through Doximity profiles and program websites: PubMed, Scopus, Google Scholar, American Society of Plastic Surgeons, and Accreditation Council for Graduate Medical Education.
    Results: Eighty-four programs were identified. There was a significant positive relationship between h-index, the number of publications, and type of research with reputation ranking (P < 0.05). After adjusting for years of experience post-training, h-index (OR = 1.24; P < 0.001) and the number of publications (OR = 1.05, P < 0.001) were significantly associated with reputation ranking. There was a statistically significant relationship between PD research fellowship completion and research output ranking (P < 0.01). After adjusting for years of experience post-training, h-index (OR = 1.05; P = 0.047) and the number of publications (OR = 1.01; P = 0.04) were significantly associated with research output ranking.
    Conclusion: Higher ranked programs tend to have PDs who have a strong record of scholarly activity, as evidenced by certain bibliometric indices.
    DOI:  https://doi.org/10.1097/GOX.0000000000004711
  42. Front Public Health. 2022 ;10 1069172
    Global research into the relationship between electronic waste and health over the last 10 years: A scientometric analysis.
    Huiting Tian, Lingzhi Chen, Jinyao Wu, Daitian Zheng, Qiuping Yang, Zeqi Ji, Jiehui Cai, Yexi Chen, Zhiyang Li.
       Introduction: The aims of this research were to conduct the first holistic and deep scientometric analysis of electronic waste and health and provide with the prediction of research trends and hot topics.
    Method: A comprehensive literature search was conducted via the Web of Science Core collection databases on 26 August 2022 to identify all articles related to electronic waste and health. A total of 652 records have been extracted from the Web of Science after applying inclusion and exclusion criteria and were analyzed using bibliometrix software of R-package, VOSviewer, and CiteSpace, visualized by tables and diagrams.
    Result: The number of publications and total citations had shown a general growth trend from 2012 to 2021, with an average annual growth rate of 23.74%. Mainland China was the significant nation with the greatest number of publications, citations, and international links. The journal publishing the most was "Science of the Total Environment" (n = 56). Huo X and Hu XJ were the top two author contributing to this field with the highest h-index (23). Over time, the focus in this field shifted to exposure to heavy metal, polychlorinated biphenyls, polybrominated biphenyl ethers, and poly- and perfluorinated alkyl substances from electronic waste, and managements, such as hydrometallurgy.
    Discussion: By this scientometric analysis, we found that the most active country, journal, organization and author contributing to this filed, as well as high impact documents and references and research hotspots. Also, we found that the hotspots might be exposure to toxic substances from electronic waste procession, its impact on human health and relevant managements. And evironmentally friendly materials to replace heavy metal mate rials, and environmentally friendly and effective recycling methods of electronic waste need to be further studied.
    Keywords:  VOSviewer; bibliometrix; electronic waste (e-waste); environment; health; scientometric
    DOI:  https://doi.org/10.3389/fpubh.2022.1069172
  43. Front Immunol. 2022 ;13 1036461
    Global trends in research of immune cells associated with hypertensive disorders of pregnancy: A 20-year bibliometric analyses (from 2001 to 2021).
    Yue Wang, Baoxuan Li, Fei Tong.
       Background: A growing evidence suggests that immune cells play a significant role in the pathogenesis of hypertensive disorders of pregnancy (HDP).Over the past 20 years, several studies have been conducted on the role of immune cells in hypertensive disorders of pregnancy. This study used bibliometric analysis to assess research hotspots and future trends in studies on immune cells in hypertensive disorders of pregnancy.
    Methods: We extracted all relevant literature on immune cells and hypertensive disorders of pregnancy from the Web of Science core collection for the period of 2001 to 2021. We used VOS Viewer, CiteSpace, R-bibliometrix and Python for bibliometric analysis.
    Results: We identified 2,388 records published in 593 journals by 9,886 authors from 2,174 universities/institutions in 91 countries/regions. The number of publications tended to increase over time, with the highest number of publications in 2021, up to 205. The USA was the country with the most publications. UNIVERSITY OF MISSISSIPPI was the most influential institution. Lamarca B, Romero R, and Saito S were the most prolific authors. Finally, three research hotspot clusters were identified based on keywords, which reflected the role of immune cells in the development of hypertensive disorders of pregnancy, the current research status,and predicted hot spots for future research.
    Conclusions: Our study systematically analyzed the role of immune cells in the pathogenesis of hypertensive disorders of pregnancy in the last 20 years. Our results indicated that immune cells, such as T cells, natural killer (NK) cells,and macrophages, and the cytokines released such as TNF-α, IFN-γ in the maternal circulation and at the maternal-fetal interface would influence the development of hypertensive disorders of pregnancy and we need further investigate the role of individual immune cells and translational studies to provide new therapeutic perspectives to mitigate adverse perinatal outcomes due to hypertensive disorders of pregnancy. In conclusion, bibliometric studies provide a general overview of immune cells in the study of hypertensive disorders of pregnancy.
    Keywords:  bibliometric analysis; hypertensive disorders of pregnancy (HDP); immune cells; inflammation; research hotspots
    DOI:  https://doi.org/10.3389/fimmu.2022.1036461
  44. Digit Health. 2023 Jan-Dec;9:9 20552076221149296
    Bibliometric analysis on the adoption of artificial intelligence applications in the e-health sector.
    Abdul Khalique Shaikh, Saadat M Alhashmi, Nadia Khalique, Ahmed M Khedr, Kaamran Raahemifar, Sadaf Bukhari.
      Artificial Intelligent (AI) applications in e-health have evolved considerably in the last 25 years. To track the current research progress in this field, there is a need to analyze the most recent trend of adopting AI applications in e-health. This bibliometric analysis study covers AI applications in e-health. It differs from the existing literature review as the journal articles are obtained from the Scopus database from its beginning to late 2021 (25 years), which depicts the most recent trend of AI in e-health. The bibliometric analysis is employed to find the statistical and quantitative analysis of available literature of a specific field of study for a particular period. An extensive global literature review is performed to identify the significant research area, authors, or their relationship through published articles. It also provides the researchers with an overview of the work evolution of specific research fields. The study's main contribution highlights the essential authors, journals, institutes, keywords, and states in developing the AI field in e-health.
    Keywords:  artificial intelligence; bibliometric analysis; e-health; health care; machine learning; smart health- care; telehealth
    DOI:  https://doi.org/10.1177/20552076221149296
  45. Medicine (Baltimore). 2023 Jan 20. 102(3): e32705
    Global research trends in the COVID-19 and digestive disease: A review of visualization and bibliometric study.
    Peiling Gan, Shu Huang, Xiao Pan, Huifang Xia, Xinyi Zeng, Wensen Ren, Lei Shi, Muhan Lü, Xian Zhou, Xiaowei Tang.
       BACKGROUND: The rapid spread of coronavirus disease 2019 (COVID-19) has attracted worldwide attention. There were also reported gastrointestinal symptoms in patients with COVID-19. This work aims to analyze the global research trends in COVID-19 and digestive disease.
    METHODS: The related papers on COVID-19 and digestive disease were identified with Pubmed and web of science core collection on September 3, 2021. Bibliometric visualization was conducted through VOSviewer and CiteSpace.
    RESULTS: The analytic research was based on original articles and reviews. There were 997 articles found, with citations ranging from 0 to 878. These articles were distributed among 86 countries and 355 journals. The USA mainly contributed (288 articles), where 3 of the top 10 institutions were located. Followed by China (215 articles) and Italy (160 articles). The highest level of scientific collaboration has been formed between the USA to China. The World Journal of Gastroenterology (39 papers) published the most significant number of articles. Concerning the research topic, the colon/small bowel had the largest number of articles, followed by the liver and pancreaticobiliary. "Liver injury," "inflammatory bowel disease," "management," and "endoscopy" were the hotspot keywords. The largest cluster of liver transplantation had offered hints regarding research frontiers.
    CONCLUSION: The analytic results showed that the liver, especially liver transplantation, and inflammatory bowel disease were the 2 most influential research topics in COVID-19 and digestive disease.
    DOI:  https://doi.org/10.1097/MD.0000000000032705
  46. Br J Gen Pract. 2023 Feb;73(727): e133-e140
    General practice-based cancer research publications: a bibliometric analysis 2013-2019.
    Kristi Milley, Sophie Chima, Napin Karnchanachari, Mairead McNamara, Paige Druce, Jon Emery.
       BACKGROUND: General practice plays a critical role in the prevention, diagnosis, management, and survivorship care of patients with cancer. Mapping research outputs over time provides valuable insights into the evolving role of general practice in cancer care.
    AIM: To describe and compare the distribution of cancer in general practice research publications by country, cancer type, area of the cancer continuum, author sex, and journal impact factor.
    DESIGN AND SETTING: A bibliometric analysis using a systematic approach to identify publications.
    METHOD: MEDLINE and Embase databases were searched for studies published between 2013 and 2019, which reported on cancer in general practice. Included studies were mapped to the cancer continuum framework. Descriptive statistics were used to present data from the included studies.
    RESULTS: A total of 2798 publications were included from 714 journals, spanning 79 countries. The publication rate remained stable over this period. Overall, the US produced the most publications (n = 886, 31.7%), although, per general population capita, Denmark produced nearly 10 times more publications than the US (20.0 publications per million compared with 2.7 publications per million). Research across the cancer continuum varied by country, but, overall, most studies focused on cancer screening, diagnosis, and survivorship. More than half of included studies used observational study designs (n = 1523, 54.4%). Females made up 66.5% (n = 1304) of first authors, but only 47.0% (n = 927) of last authors.
    CONCLUSION: Cancer in general practice is a stable field where research is predominantly observational. There is geographical variation in the focus of cancer in general practice research, which may reflect different priorities and levels of investment between countries. Overall, these results support future consideration of how to improve under-represented research areas and the design, conduct, and translation of interventional research.
    Keywords:  bibliometrics; cancer; general practice; primary health care
    DOI:  https://doi.org/10.3399/BJGP.2022.0025
  47. Front Public Health. 2022 ;10 1040175
    Knowledge mapping of COVID-19 and dentistry: A bibliometric analysis.
    Jia Chen, Qian Zhang, Xin Liu, Ying Han, Qiming Gong.
       Background: COVID-19 has a significant impact on dental medicine. The present study aims to overview dental-related research on COVID-19 by visual mapping method.
    Methods: We analyzed the publications in the "Dentistry Oral Surgery Medicine" category in the Web of Science core collection. On June 10, 2022, we conducted an advanced search using the items TS = ("Novel coronavirus 2019" or "COVID 19" or "Coronavirus disease 2019" or "2019-nCOV" or "SARS-CoV-2" or "coronavirus-2") and WC = ("Dentistry Oral Surgery medicine") to screen publications in the dental field that focus on COVID-19 or SARS-CoV-2. The contributions of authors, journals, institutions, and countries were described using Microsoft Excel 2010 and VOSviewer. The keywords co-occurring analysis and references analysis were visualized using VOSviewer and CiteSpace.
    Results: A total of 1,732 papers were identified between 2020 and 2022. The United States, the United Kingdom, and Brazil were three major contributors to this field. Univ São Paulo (Brazil) ranked first with 55 publications in this field. Martelli Junior, Hercilio from Universidade Jose do Rosario Vellano (Brazil) was the most prolific author with 19 publications. Oral Diseases and British Dental Journal were the two most productive journals. The central topics were dental practice and infection control, oral manifestation related to COVID-19, dental education and online learning, teledentistry, and mental health problems.
    Conclusion: The growth rate of publications regarding dental research on COVID-19 has risen sharply. Research topics shifted from "Dental practice and infection control, oral manifestation related to COVID-19" in 2020 to "Dental education and online learning, teledentistry, mental health problems," which are three important research topics for the future.
    Keywords:  COVID-19; CiteSpace; VOSviewer; bibliometric analysis; dentistry; oral surgery medicine
    DOI:  https://doi.org/10.3389/fpubh.2022.1040175
  48. Front Microbiol. 2022 ;13 1074003
    Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis.
    Runzhi Huang, Mengyi Zhang, Yuwei Lu, Dayuan Xu, Yifan Liu, Minghao Jin, Shuyuan Xian, Siqiao Wang, Xirui Tong, Jianyu Lu, Wei Zhang, Weijin Qian, Jieling Tang, Yiting Yang, Bingnan Lu, Zhengyan Chang, Xin Liu, Shizhao Ji.
       Background: Rheumatic diseases (RD) are a group of multi-system inflammatory autoimmune diseases whose causes are still under study. In the past few decades, researchers have found traces of the association between rheumatic diseases and intestinal microbiota, which can partially explain the pathogenesis of rheumatic diseases. We aimed to describe the research trend and main divisions on how gut flora interreacts with rheumatic diseases, and discussed about the possible clinical applications.
    Methods: We analyzed bibliometric data from the Web of Science core collection (dated 15th May 2022). Biblioshiny R language software packages (bibliometrix) were used to obtain the annual publication and citations, core sources according to Bradford's law, and country collaboration map. We designed and verified the keyword co-occurrence network and strategic diagram with the help of VOSviewer and CiteSpace, subdivided the research topic into several themes and identified research dimensions. The tables of most local cited documents and core sources were processed manually. Furthermore, the Altmetric Attention Score and the annual Altmetric Top 100 were applied to analyze the annual publication and citation.
    Results: From a total of 541 documents, we found that the overall trend of annual publication and citation is increasing. The major research method is to compare the intestinal microbial composition of patients with certain rheumatic disease and that of the control group to determine microbial alterations related to the disease's occurrence and development. According to Bradford's law, the core sources are Arthritis and Rheumatology, Annals of the Rheumatic Diseases, Current Opinion in Rheumatology, Nutrients, Rheumatology, and Journal of Rheumatology. Since 1976, 101 countries or regions have participated in studies of rheumatology and intestinal microbes. The United States ranks at the top and has the broadest academic association with other countries. Five themes were identified, including the pivotal role of inflammation caused by intestinal bacteria in the rheumatic pathogenesis, the close relationship between rheumatic diseases and inflammatory bowel disease, immunoregulation mechanism as a mediator of the interaction between rheumatic diseases and gut flora, dysbiosis and decreased diversity in intestine of patients with rheumatic diseases, and the influence of oral flora on rheumatic diseases. Additionally, four research dimensions were identified, including pathology, treatment, disease, and experiments.
    Conclusion: Studies on rheumatic diseases and the intestinal microbiota are growing. Attention should be paid to the mechanism of their interaction, such as the microbe-immune-RD crosstalk. Hopefully, the research achievements can be applied to diseases' prevention, diagnosis, and treatment, and our work can contribute to the readers' future research.
    Keywords:  bibliometric analysis; dysbiosis; host microbial interactions; intestinal microbiota; rheumatic diseases
    DOI:  https://doi.org/10.3389/fmicb.2022.1074003
  49. Heliyon. 2023 Jan;9(1): e12770
    Bibliometric analysis of traditional Chinese medicine research on heart failure in the 21st century based on the WOS database.
    Yun-Hu Chen, Mo-Qing Yin, Li-Hua Fan, Xue-Chun Jiang, Hong-Feng Xu, Tao Zhang, Xing-Yu Zhu.
       Introduction: Heart Failure (HF) is a key area of research in human medicine, and traditional Chinese medicine (TCM) is an important branch of this field. This study aimed to use bibliometric methods to sort out the trajectory of TCM research on HF in this century (2000-2022) from a high dimension and to analyze its characteristics, hotspots and frontiers.
    Methods: In this study, the search formula "TS=(("traditional Chinese medicine") OR ("Chinese medicine")) AND TS=("heart failure")" was used to find relevant studies included in the Web of Science Core Collection from 2000 to 2022. Targeted literature records were analyzed and mapped using CiteSpace and VOSviewer.
    Results: The authors and collaborators of this study were still in the formation process, but several well-known scholars were included: YONG WANG, WEI WANG, etc. The main research institutions in this research area were Beijing Univ Chinese Med, China Acad Chinese Med Sc, etc. The main country of study was China. Current research hotspots and frontiers were Qili Qiangxin capsules, extracts (Tanshinone ⅡA, Panax ginseng, etc.), cardiac hypertrophy, ventricular remodeling, oxidative stress, signaling pathways, network pharmacology, etc. Influential journals that publish papers in this field were the Journal of Ethnopharmacology, Scientific Reports, Biomedicine & Pharmacotherapy, etc. The top 3 co-cited journals were Circulation, J ethnopharmacol, and J am coll cardiol.
    Conclusions: We analyzed valuable details in TCM research on HF in the 21st century, which may help researchers identify potential collaborators and partner institutions, hotspots, and frontiers in the field.
    Keywords:  Bibliometrics; Heart failure (HF); Knowledge mapping; Systematic review; Traditional Chinese medicine (TCM); Visual analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e12770
  50. Front Cardiovasc Med. 2022 ;9 1051383
    A bibliometric analysis on the progress of myocardial bridge from 1980 to 2022.
    Liang Chen, Wen-Yuan Yu, Rui Liu, Ming-Xin Gao, Bo-Lin Wang, Xiao-Hang Ding, Yang Yu.
       Introduction: Although the vast majority of patients with a myocardial bridge (MB) are asymptomatic, the anomaly was found to be associated with stable or unstable angina, vasospastic angina, acute coronary syndrome, and even malignant arrhythmias and sudden cardiac death in some cases.
    Methods: By retrieving the relevant literature on MB from 1 January 1980 to 31 July 2022 from the Web of Science Core Collection (WoSCC) database, we used the bibliometric tools, including CiteSpace, VOS viewer, and alluvial generator, to visualize the scientific achievements on MB.
    Results: A total of 630 articles were included. The number of published articles was in a fluctuating growth trend. These publications came from 37 contries, led by the USA and China. The leading country on MB was the United States, the leading position among institutions was Stanford University, and the most productive researcher on MB was Jennifer A. Tremmel. After analysis, the most common keywords were myocardial bridge, mortality, coronary angiography, descending coronary artery, and sudden death.
    Conclusion: Our findings can aid researchers in understanding the current state of MB research and in choosing fresh lines of inquiry for forthcoming investigations. Prevalence and prognosis, mechanism atherosclerosis, hemodynamic significance, and molecular autops will likely become the focus of future research. In addition, more studies and cooperations are still needed worldwide.
    Keywords:  atherosclerosis; bibliometric; management; myocardial bridge; review
    DOI:  https://doi.org/10.3389/fcvm.2022.1051383
  51. J Evid Based Dent Pract. 2023 Jan;pii: S1532-3382(22)00103-8. [Epub ahead of print]23(1S): 101780
    A Bibliometric Mapping Study of the Literature on Oral Health-related Quality of Life.
    Xueqian Yu, Yanning Chen, Yueyang Li, Jialan Hong, Fang Hua.
       BACKGROUND: Oral health is an indispensable component of overall health, and oral health status significantly influences people's physical, mental, and social well-being. Oral health-related quality of life (OHRQoL), an important and widely used dental patient-reported outcome (dPRO), is attracting more and more researchers' attention and interest. This study aimed to analyze and map the existing scientific literature regarding OHRQoL through a bibliometric approach, including a summary of the characteristics of OHRQoL-related publications, the identification of prolific entities, high-frequency keywords analysis, and research trend analysis via periodic high-impact keywords.
    METHODS: A literature search was conducted in the Web of Science Core Collection to collect OHRQoL-related original research and review articles. After examination and deduplication, the following bibliometric information was extracted from each article: title, abstract, keywords, authors, affiliations, geographic origin (countries/regions), year of publication, journal name, and references. Various scientometric mapping tools including Microsoft Office spreadsheet, VOSviewer, Biblioshiny R-package software, and Scimago Graphica were used to analyze basic bibliometric parameters, leading producers, high-impact keywords, and research trends.
    RESULTS: A total of 3324 OHRQoL-related articles (3119 original research articles and 205 review papers) were collected, which received 65,704 citations. A total of 9950 authors from 2429 organizations contributed to this body of research. Prolific authors from Europe, USA, Brazil, New Zealand, China, and Canada were identified, and they also centered collaboration clusters in the co-author network. Community Dentistry and Oral Epidemiology was the most prolific journal. Twenty-one keywords with more than 200 occurrences, and 23 keywords with more than 150 occurrences, were identified for publications of 1994-2021 and 2012-2021, respectively. Keyword analysis revealed hot topics such as instrument development and validation, studies targeting children and adolescents, as well as clinical studies in operative dentistry, implantology, orthodontics, and community dentistry. Oral Health Impact Profile is the most commonly used instrument in OHRQoL-related research.
    CONCLUSIONS: OHRQoL is an impactful topic in dental health care as it is not only useful in dental research and patient-centered clinical outcome measures but also provides valuable guidance in dental public health administration and policy making. OHRQoL-related research presents a dynamic landscape and is expected to continue presenting high productivity and broad application in the future.
    Keywords:  Bibliometrics; Dental patient-reported outcome; Oral health-related quality of life; Scientometrics
    DOI:  https://doi.org/10.1016/j.jebdp.2022.101780
  52. Front Psychol. 2022 ;13 1094959
    CiteSpace-based global science, technology, engineering, and mathematics education knowledge mapping analysis.
    Duo Yang, Xiaopeng Wu, Jiali Liu, Jincheng Zhou.
      To better understand the latest developments in global science, technology, engineering, and mathematics (STEM) education research, this study collected STEM education research materials to sort out the development of STEM education as a whole, so as to get a clearer path and trend of STEM education development. This study conducted a visualization and quantitative analysis of the literature on STEM education research in Science Citation Index Extended (SCI-E) and Social Science Citation Index (SSCI) using the CiteSpace (5.8.R3) tool. First, the basic information of STEM education was analyzed in terms of annual publication volume, authors, countries, and research institutions. Secondly, the main fields, basic contents and research hotspots of this research were analyzed by keyword co-occurrence and keyword time zone mapping. Finally, the research frontiers and development trends are presented through co-citation clustering and high-frequency keyword bursts. The research hotspots are focused on engineering education, teachers' professional development, and gender differences. The research frontiers are mainly related to teacher professional development, 21st century skills, early childhood creativity, and gender differences. This study systematically analyzes the latest developments in global STEM education research, which is beneficial for readers to understand the full picture of STEM education research so that researchers can conduct more in-depth studies and promote better development of STEM education. The number of analyzed literature is limited. We only analyzed articles from SSCI and SCI-E databases, and the articles were written in English. In addition, we only analyzed the literature and lacked empirical studies on the findings of the literature.
    Keywords:  CiteSpace; STEM education; bibliometrics; knowledge graph; knowledge mapping
    DOI:  https://doi.org/10.3389/fpsyg.2022.1094959
  53. Front Oncol. 2022 ;12 1071860
    Hepatic arterial infusion chemotherapy in hepatocellular carcinoma: A bibliometric and knowledge-map analysis.
    Mei Li, Kai Zhang, Ji'an He, Weihao Zhang, Tianye Lv, Li Wang, Wenge Xing, Haipeng Yu.
       Background: In recent years, hepatic arterial infusion chemotherapy (HAIC) has gained popularity in the treatment of hepatocellular carcinoma. Although several studies have been published, no bibliometric analysis have been conducted on this topic.
    Objectives: To understand the development status and future trends in the application of HAIC, we conducted bibliometric analysis to examine the cooperation and influence among countries, institutions, authors, and journals.
    Methods: All relevant articles and reviews on the use of HAIC in HCC treatment were retrieved from the Web of Science database. A bibliometric analysis of countries, institutions, journals, authors, and keywords related to this field was performed using R and VOSviewer software. The main aspects analyzed were the research status and key fields of HAIC in HCC treatment.
    Results: A total of 1026 articles published in 292 journals by 4937 authors from 959 institutions between 1974 and 2021 were retrieved. A rapid increase in articles published after 1990 was observed, which reached the peak in 2021. Japan had the most publications and citations. Yonsei University, Sun Yat-sen University, and Hiroshima University were the three leading institutions in research on this topic. Kwang-Hyub Han and Masatoshi Kudo have the greatest academic influence in this field. Most publications were made in the Hepato-Gastroenterology, whereas cancer had the most citations. The main aspects of HAIC treatment of HCC include HAIC and TACE, chemotherapy drug selection, HAIC and targeted therapy and immunotherapy, HAIC and surgery, and hepatotoxicity. Keywords such as FOLFOX, lenvatinib, hepatic arterial infusion chemotherapy are hot words in this field in recent years.
    Conclusion: The research on the use of HAIC in the treatment of HCC has been on the rise. Currently, HAIC combined with targeted therapy or immunotherapy has attracted significant attention.
    Keywords:  FOLFOX; bibliometric; data mining; hepatic arterial infusion chemotherapy; hepatocellular carcinoma
    DOI:  https://doi.org/10.3389/fonc.2022.1071860
  54. Medicine (Baltimore). 2023 Jan 27. 102(4): e32784
    Trends of denosumab-related publications in web of science.
    Xiaohong Jiang, Tianyu Xie, Wenyu Feng, Zhaojie Qin, Shijie Liao, Yun Liu, Shenglin Lu, Mingwei He, Qingjun Wei.
      Denosumab is a human monoclonal antibody that targets nuclear factor-kappa B ligand and is highly effective in blocking bone resorption. Bibliometrics can intuitively show the research development process, research status, research hotspots and development trend of a certain topic for researchers. This study assessed the course of research and development for denosumab in terms of publications over the past 2 decades. Web of Science databases were searched to identify publications related to research on denosumab from January 1, 2005 to December 31, 2022. The VOS Viewer software (version 1.6.17) and Bibliometrix package in R (version 4.1.3) were used in this study. There were 5119 denosumab-related publications during this period. The total number of citations of denosumab-related publications reached 94917. The most articles were published in the field of Endocrinology Metabolism. As an international language, English remains the most popular language for writing papers. Five of the top ten institutions originated in the USA. Through the VOS Viewer analysis, we found that the relationships between Amgen Inc. with its collaborations were grouped into 4 clusters, the USA was the mainland for research and development on denosumab, closely collaborating with many other countries, such as Canada, Japan, England, and China. Wagman RB from USA was the most prolific author with 119 publications. The journal with the most publications was Osteoporosis International (481 publications). The most cited article was "Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis" with 2053 citations. The clinical trial comprised 6 of the 10 most frequently cited publications, and the rest consisted of reviews. The most frequent keywords for publications since January 1, 2014 were "prevention" and "management," indicating that a number of prevention and management measures have been developed to regulate the use of denosumab in treating osteoporosis. Our research provided a comprehensive review of denosumab-related publications, suggesting that the development of denosumab is a long process and numerous clinical trials have been conducted before applications in clinical settings.
    DOI:  https://doi.org/10.1097/MD.0000000000032784
  55. Middle East Afr J Ophthalmol. 2022 Jan-Mar;29(1):29(1): 33-37
    Fate of Abstracts Presented at the Saudi Ophthalmology Society Conferences 2015-2018.
    Abdulaziz K Alsarhani, Abdullah I Almater, Mansour A Alobrah, Rahaf M Al Malawi, Waleed K Alsarhani.
       PURPOSE: The aim of the study was to determine the publication rates of abstracts presented at the annual Saudi Ophthalmology Society (SOS) Conferences from 2015 to 2018.
    METHODS: This is a cross-sectional study on abstracts collected from the scientific programs for the SOS meetings from 2015 to 2018. Titles and first authors' names were used in the search process on PubMed. A Chi-square test was conducted to compare between the categorical variables. Kruskal-Wallis test was used for nonnormally distributed variables.
    RESULTS: A total of 365 abstracts were presented in the SOS Conferences from 2015 to 2018. In the SOS meetings (2015-2018), the publication rate was 45.7%. Seventy-two (43.1%) of the published abstracts were published in journals with an impact factor. The mean impact factor was 1.4 ± 1.9. The median time to publication was 12.0 months (range: 0-60 months). On univariate analysis, basic science (P < 0.001), abstracts on rare diseases (P = 0.003), affiliation with eye hospitals (P < 0.001), and public hospitals (0.007) were associated with a higher publication rate. On multivariate analysis, basic science studies (odds ratio [OR]: 4.23, confidence interval [CI]: 1.77-10.12, P = 0.001), rare topic-related abstracts (OR: 2.03, CI: 1.22-3.38, P = 0.007), and eye center affiliation (OR: 1.67, CI: 1.03-2.68, P = 0.036) were associated with a better publication rate. The factors associated with publication in high impact factor journals were oral abstracts (P = 0.007) and noncase report abstracts (P = 0.023).
    CONCLUSION: Basic science studies, rare topic-related abstracts, and first author affiliation with an eye center were all associated with a higher publication rate. Orally presented and noncase report abstracts increased the chance of publication in higher impact factor journals.
    Keywords:  Ophthalmology abstracts; Saudi ophthalmology; ophthalmology meetings; research productivity
    DOI:  https://doi.org/10.4103/meajo.meajo_67_22
  56. BMJ Support Palliat Care. 2023 Jan 26. pii: spcare-2022-004108. [Epub ahead of print]
    Palliative care and COVID-19: a bibliometric analysis.
    Alessandra Bernardis, Valentina Gonzalez-Jaramillo, Andreas S Ebneter, Steffen Eychmüller.
       OBJECTIVE: To assess the impact of COVID-19 on the palliative care (PC) publication trend in the last 10 years and the collaboration between countries and main topics that were discussed in the papers.
    METHODS: We used Scopus to identify publications on PC between 2012 and 2021 and publications about PC and COVID-19 between 2020 and 2021. We used VOSviewer to assess the main topics using the keywords from the papers and to assess country collaboration.
    RESULTS: 1937 publications resulted. An increase in publications about PC was observed during the pandemic, only partially explained by OVID-19-related publications. Cancer-related PC publications were the ones with the most marked increase. We identified six clusters in the distribution of the keywords: bioethics, cancer, nursing home/telemedicine, public health, caring and PC following the WHO definition. The countries with higher number of publications were the United States and England.
    CONCLUSION: We showed an increase in the number of PC publications in the last 2 years that was only partially explained by COVID-19-related publications. Most of the publications increase was due to cancer-related publications, since, during the time of the pandemic, publications on cancer and PC increased markedly, while those on heart failure, lung disease and dementia, remained constant.
    Keywords:  COVID-19; end of life care; ethics; family management; supportive care; terminal care
    DOI:  https://doi.org/10.1136/spcare-2022-004108
  57. J Adv Med Educ Prof. 2023 Jan;11(1): 50-60
    Comparison of Gamification, Game-Based Learning, and Serious Games in Medical Education: A Scientometrics Analysis.
    Mohadeseh Zohari, Neda Karim, Shiva Malgard, Maryam Aalaa, Shadi Asadzandi, Sharareh Borhani.
       Introduction: Game in education aims to enhance human motivation and performance in a given activity. Gamification experts and health researchers are still unsure about the status of progress of game for health. So, to fill in this gap, the present study aimed to analyze scientific productions to identify production trends, subject areas, countries, institutes, and authors in these three areas on gamification, game-based learning, and serious games in medical education, as well as to determine co-authorship patterns.
    Methods: The present descriptive quantitative research was conducted through scientometric analysis by using co-authorship networks in gamification, game-based learning, and serious games. First, an advanced search was performed from 1990 to 2020 and the studies were retrieved from Web of sciences, on Aug 17, 2021 The plain text format of data was inputted to Microsoft Excel, CiteSpace and Gephi to analyze scientometric maps for the three domains. Subsequently, the required indicators to review co-authorship networks were obtained: Degree centrality, Betweenness centrality, Closeness centrality, Density, Clustering coefficient, collaboration index and collaboration coefficient.
    Results: There were 466 documents in gamification, 155 documents in game-based learning, and 295 documents in serious games. The results indicated the rising trend of scientific publications on the three domains. US was a prolific country in all three domains. Author collaboration has remarkably increased, although the number of single-author articles is still high.
    Conclusion: Due to the increasing growth of publications on these three domains, research can be continued by forming specialized groups and supporting joint publications. Also, research policy-makers should promote author collaborations on the national and international scale.
    Keywords:   Game-based learning; Gamification; Medical education
    DOI:  https://doi.org/10.30476/JAMP.2022.94787.1608
  58. Sci Total Environ. 2023 Jan 18. pii: S0048-9697(23)00279-6. [Epub ahead of print]869 161664
    The latest research trends in the removal of cesium from radioactive wastewater: A review based on data-driven and visual analysis.
    Heyao Liu, Lizhi Tong, Minhua Su, Diyun Chen, Gang Song, Ying Zhou.
      The widespread adoption of nuclear energy has increased the amount of radioactive cesium (Cs) that is discharged into waste streams, which can have environmental risks. In this paper, we provide a comprehensive summary of current advances in aqueous Cs removal by employing a bibliometric analysis. We collected 1580 articles related to aqueous Cs treatment that were published on the Web of Science database between 2012 and 2022. By applying bibliometric analysis combined with network analysis, we revealed the research distribution, knowledge base, research hotspots, and cutting-edge technologies in the field of aqueous Cs removal. Our findings indicate that China, Japan, and South Korea are the most productive countries with respect to Cs removal research. In addition, both historic events and environmental threats might have contributed to research in Asian countries having a higher focus on Cs removal as well as strong international cooperation between Asian countries. A detailed keyword analysis reveals the main knowledge base for aqueous Cs removal and highlights the potential of the adsorption-based method for treating Cs contamination. Furthermore, the results reveal that exploration of functional materials is a popular research topic in the field of Cs removal. Since 2012, novel materials, including Prussian blue, graphene oxide, hydrogel and nanocomposites, have been widely investigated because of their high capacity for Cs removal. On the basis of the detailed information, we report the latest research trends on aqueous Cs removal, and propose future research directions and describe the challenges related to effective Cs treatment. This scientometric review provides insights into current research hotspots and cutting-edge trends in addition to contributing to the development of this crucial research field.
    Keywords:  Adsorption; Bibliometric analysis; Cesium removal; Radionuclides; Visualization
    DOI:  https://doi.org/10.1016/j.scitotenv.2023.161664
  59. World Neurosurg. 2023 Jan 18. pii: S1878-8750(23)00074-8. [Epub ahead of print]
    Bibliometric Analysis of the Neurosurgery Publication Productivity of Southeast Asia in the Previous Decade.
    Muhammad Kamil, Zainal Muttaqin, Ryosuke Hanaya, Kazunori Arita, Koji Yoshimoto.
      
    Keywords:  Bibliometric analysis; Developing countries; Global neurosurgery; Neurosurgery; Neurosurgery education; Southeast Asia
    DOI:  https://doi.org/10.1016/j.wneu.2023.01.059
  60. JB JS Open Access. 2023 Jan-Mar;8(1):pii: e22.00072. [Epub ahead of print]8(1):
    Factors Associated with the Success and Timing of Orthopaedic Surgery Resident Research Thesis Project Publication.
    Andrew W Kuhn, Paul M Inclan, David M Brogan, Alexander W Aleem, Robert H Brophy.
      Scholarship and research are important aspects of orthopaedic surgery training. Many orthopaedic surgery residency programs have developed dedicated research curricula, often culminating in a capstone thesis project with the intended goal of peer-reviewed publication. However, data on the success of these programs are scarce. The purpose of the current study was to determine the success rate and time to publication of resident research thesis projects at our own institution while evaluating factors associated with these outcomes.
    Methods: Resident research thesis projects performed over the past 15 years were aggregated and reviewed. Additional data regarding the projects and former trainees who performed them were collected using public resources which included measures of current academic aptitude (i.e., H-index and number of publications) as well as project and publication characteristics. Cox and linear regression analyses were conducted to assess the relation between numerous predictor variables and the success and time to publication. All analyses were conducted at the 95% confidence interval (CI) level.
    Results: Sixty-eight (n = 68; 83%) resident research thesis projects were published an average of 2,582.8 days, or roughly 7 years from the start of their residency training. Graduate adjusted H-index was associated with increased success and decreased time to publication (hazard ratio 1.183 [95% CI: 1.059-1.322], p = 0.003). A lower journal impact factor was associated with taking significantly shorter time to reach publication (F(1,66) = 7.839, p = 0.007; Β1 = 146.45, p = 0.007). Study type (clinical vs. laboratory), posttraining practice setting (academic vs. private), and whether the research topic was within the same area of the trainee's matched fellowship(s) did not predict publication success.
    Discussion/Conclusion: Over the past 15 years, 83% of orthopaedic resident research thesis projects at our institution were published. A higher adjusted H-index was associated with greater completion and faster timing to publication. A lower journal impact factor was also associated with quicker publication. These data highlight the publication metrics of a formalized resident research program and identify factors associated with success and timing of publication.
    DOI:  https://doi.org/10.2106/JBJS.OA.22.00072
  61. Front Public Health. 2022 ;10 1089418
    Diseases spectrum in the field of spatiotemporal patterns mining of infectious diseases epidemics: A bibliometric and content analysis.
    Weili Lu, Hongyan Ren.
      Numerous investigations of the spatiotemporal patterns of infectious disease epidemics, their potential influences, and their driving mechanisms have greatly contributed to effective interventions in the recent years of increasing pandemic situations. However, systematic reviews of the spatiotemporal patterns of communicable diseases are rare. Using bibliometric analysis, combined with content analysis, this study aimed to summarize the number of publications and trends, the spectrum of infectious diseases, major research directions and data-methodological-theoretical characteristics, and academic communities in this field. Based on 851 relevant publications from the Web of Science core database, from January 1991 to September 2021, the study found that the increasing number of publications and the changes in the disease spectrum have been accompanied by serious outbreaks and pandemics over the past 30 years. Owing to the current pandemic of new, infectious diseases (e.g., COVID-19) and the ravages of old infectious diseases (e.g., dengue and influenza), illustrated by the disease spectrum, the number of publications in this field would continue to rise. Three logically rigorous research directions-the detection of spatiotemporal patterns, identification of potential influencing factors, and risk prediction and simulation-support the research paradigm framework in this field. The role of human mobility in the transmission of insect-borne infectious diseases (e.g., dengue) and scale effects must be extensively studied in the future. Developed countries, such as the USA and England, have stronger leadership in the field. Therefore, much more effort must be made by developing countries, such as China, to improve their contribution and role in international academic collaborations.
    Keywords:  bibliometrics; content analysis; diseases spectrum; infectious diseases; research directions; research gaps; spatiotemporal patterns
    DOI:  https://doi.org/10.3389/fpubh.2022.1089418
  62. PLoS One. 2023 ;18(1): e0280016
    Correlations between the selection of topics by news media and scientific journals.
    Melanie Leidecker-Sandmann, Lars Koppers, Markus Lehmkuhl.
      The aim of this study is to reveal a robust correlation between the amount of attention international journalism devotes to scientific papers and the amount of attention scientific journals devote to the respective topics. Using a Mainstream-Media-Score (MSM) ≥ 100 (which we regard as an indicator for news media attention) from the altmetrics provider Altmetric, we link 983 research articles with 185,166 thematically similar articles from the PubMed database (which we use to operationalize attention from scientific journals). The method we use is to test whether there is a concomitant increase in scientific attention after a research article has received popular media coverage. To do so, we compare the quotient of the number of thematically similar articles published in scientific journals during the period before and after the publication of an MSM ≥ 100 article. Our main result shows that in 59 percent of cases, more thematically similar articles were published in scientific journals after a scientific paper received noteworthy news media coverage than before (p < 0.01). In this context, we neither found significant differences between various types of scientific journal (p = 0.3) nor between scientific papers that were originally published in renowned opinion-leading journals or in less renowned, non-opinion-leading journals (p = 0.1). Our findings indicate a robust correlation between the choice of topics in the mass media and in research. However, our study cannot clarify whether this correlation occurs because researchers and/or scientific journals are oriented towards public relevance (publicity effect) or whether the correlation is due to the parallelism of relevance attributions in quality journalism and research (earmark hypothesis). We infer that topics of social relevance are (more) likely to be picked up by popular media as well as by scientific journals. Altogether, our study contributes new empirical findings to the relationship between topic selection in journalism and in research.
    DOI:  https://doi.org/10.1371/journal.pone.0280016
  63. Front Pediatr. 2022 ;10 938810
    A bibliometric analysis of preoperative anxiety research (2001-2021).
    Siyuan Sun, Jingjing Feng, Zhiwei Fu, Zhengyi Lu, Jiafeng Chen, Mingyan Hua, Diansan Su, Juan Gu.
      Recently, mental health has received increasing attention, particularly preoperative anxiety, which constitutes a bad emotional experience for surgical patients. Many experts have studied preoperative anxiety in terms of its related risk factors, interventions, and postoperative effects; however, there has been no systematic analysis of published articles. This paper presents a bibliometric review of documents related to preoperative anxiety published between 2001 and 2021. A detailed data analysis of 1,596 publications was conducted using CiteSpace and VOSviewer. Since the 20th century, the field of preoperative anxiety has gradually developed; research began around 2000 and has made a huge leap forward since 2016. Developed countries, led by the United States, were the first to conduct research, but preoperative anxiety research in developing countries like Turkey and China has gradually increased and led to an irreplaceable contribution. Intervention has remained the main topic of preoperative anxiety research, and measures have developed from premedication to the provision of education and information. Moreover, the use of advanced equipment such as virtual reality has emerged with great popularity. Based on previous research, the application of virtual reality combined with pediatric patients will become a new research direction.
    Keywords:  bibliometric analysis; hotspot; preoperative anxiety; research front; web of science
    DOI:  https://doi.org/10.3389/fped.2022.938810
  64. Front Cardiovasc Med. 2022 ;9 941374
    Bibliometric evaluation of 2011-2021 publications on hydrogen sulfide in heart preservation research.
    Mingcong Chen, Qian Zhou, Fei Wu, Fang Sun, Yang Meng, Yang Zhang, Mingyi Zhao.
       Background: Hydrogen sulfide (H2S) is known for its unpleasant odor and severe toxicity. However, an in-depth study of H2S showed that it can be used as an important messenger, which can play important physiological and pathological roles in vitro and in vivo. In recent years, the application of H2S in the field of cardiac preservation has attracted the interest and attention of scholars worldwide. H2S plays an effective and protective role in cardiac ischemia/reperfusion injury through antioxidant, anti-inflammatory, and antiapoptotic mechanisms.
    Objective: The purpose of this study is to analyze the current scientific achievements on the application of H2S in the field of cardiac preservation and to provide new ideas for further research.
    Methods: TS = ("hydrogen sulfide" OR "hydrogen sulfide") AND TS = ("cardiac" OR "heart" OR "myocardium" OR "hearts") AND TS = ("reperfusion" or "transplantation" or "implanted" or "transplant" or "implantation" or "migration" or "preservation" or "grafting" OR "ischemia" OR "perfusion" or "conservation" or "preserve" or "reservation") AND DT = (Article OR Review) AND LA = (English) were used as search strategies for data collection from the Science Citation Index-Expanded database of the Web of Science Core Collection. CiteSpace 5.8. R3 and Microsoft Office Excel 2019 were used for data analysis.
    Results: A total of 429 related articles were included, and the total number of articles showed a fluctuating upward trend. We used CiteSpace 5.8. R3 and Microsoft Excel 2019 to evaluate and visualize the results, analyzing institutions, countries, journals, authors, co-cited references, and keywords.
    Conclusions: As increasing evidence shows that H2S plays an indispensable role in the field of cardiac preservation, its mechanistic research and clinical application may become the main focus of future research.
    Keywords:  CiteSpace; bibliomeric analysis; heart preservation; hydrogen sulfide; visualization analysis
    DOI:  https://doi.org/10.3389/fcvm.2022.941374
  65. J Anesth. 2023 Jan 23.
    Authorship by gender in anesthesiology journals: a retrospective cross-sectional study for Japan.
    Michiko Kinoshita, Mina Takahashi, Katsuya Tanaka, Yoko Sakai.
       PURPOSE: Although it is important to recognize gender disparities in publishing to achieve gender diversity, women's authorship in Japan remains unclear. Therefore, this study aimed to investigate the percentage and analyze the trends of articles authored and published in anesthesiology journals by Japanese female authors.
    METHODS: The genders of the first and last authors affiliated with Japanese institutions were surveyed in the Journal of Anesthesia (JA) (1990, 1995, and 2000-2022) and 11 international anesthesiology journals (2010-2022).
    RESULTS: We included 845 and 819 original research articles from JA in the analyses of the first and last authors, respectively. The proportion of female first authors significantly increased from 41 (11.7%) out of 351 before 2009 to 119 (24.1%) out of 494 after 2010 (p < 0.001). The proportion of female last authors was 11 (3.3%) out of 335 before 2009 and 22 (4.5%) out of 484 after 2010, respectively, with no significant difference (p = 0.470). We included 624 and 572 original research articles from international anesthesiology journals in the analyses of first and last authors, respectively. Among these, there were 134 (21.5%) and 23 (4.0%) female first and last authors, respectively. These proportions in international anesthesiology journals did not significantly differ from those in JA (p = 0.334, p = 0.789, respectively).
    CONCLUSION: The percentage of female first authors has increased, commensurate with the percentage of female anesthesiologists. However, the percentage of female last authors has not increased and remains low in Japan.
    Keywords:  Anesthesiology; Authorship; Diversity; Gender gap; Woman
    DOI:  https://doi.org/10.1007/s00540-023-03165-9
  66. Front Psychol. 2022 ;13 1079955
    Development and status of moral education research: Visual analysis based on knowledge graph.
    Jingying Chen, Yidan Liu, Jian Dai, Chengliang Wang.
       Introduction: Moral education is an educational process of the continuation, construction, and transformation of moral and social norms, and is an important guarantee for the sustainable vitality of human morality.
    Methods: With bibliometrics applied and VOSviewer and CiteSpace as tools, this paper systematically analyzes 497 articles published in the Social Sciences Citation Index of Web of Science core collection from 2000 to 2022 in the field of moral education research.
    Results: By quantifying specific performance information in the field of moral education in terms of authors, journals, organizations and countries, this paper identifies the highly productive authors and organizations, as well as core journals (i.e., the Journal of Moral Education). A cluster analysis is used to show the knowledge structure, and an evolutionary analysis to present the macro-development trend of moral education.
    Discussion: In this paper, the comprehensive description of the research topics on moral education clarifies the development model and disciplinary prospect of the moral education research, and provides theoretical and practical support for the continuous development and application practice of the moral education research.
    Keywords:  bibliometrics; knowledge graph; moral education; moral instruction; visual analysis
    DOI:  https://doi.org/10.3389/fpsyg.2022.1079955
  67. Front Oncol. 2022 ;12 1039882
    Knowledge atlas of antibody-drug conjugates on CiteSpace and clinical trial visualization analysis.
    Peizhuo Yao, Yinbin Zhang, Shuqun Zhang, Xinyu Wei, Yanbin Liu, Chong Du, Mingyou Hu, Cong Feng, Jia Li, Fang Zhao, Chaofan Li, Zhen Li, Lisha Du.
       Objective: Antibody-drugs conjugates (ADCs) are novel drugs with highly targeted and tumor-killing abilities and developing rapidly. This study aimed to evaluate drug discovery and clinical trials of and explore the hotspots and frontiers from 2012 to 2022 using bibliometric methods.
    Methods: Publications on ADCs were retrieved between 2012 and 2022 from Web of Science (WoS) and analyzed with CiteSpace 6.1.R2 software for the time, region, journals, institutions, etc. Clinical trials were downloaded from clinical trial.org and visualized with Excel software.
    Results: A total of 696 publications were obtained and 187 drug trials were retrieved. Since 2012, research on ADCs has increased year by year. Since 2020, ADC-related research has increased dramatically, with the number of relevant annual publications exceeding 100 for the first time. The United States is the most authoritative and superior country and region in the field of ADCs. The University of Texas MD Anderson Cancer Center is the most authoritative institution in this field. Research on ADCs includes two clinical trials and one review, which are the most influential references. Clinical trials of ADCs are currently focused on phase I and phase II. Comprehensive statistics and analysis of the published literature and clinical trials in the field of ADCs, have shown that the most studied drug is brentuximab vedotin (BV), the most popular target is human epidermal growth factor receptor 2 (HER2), and breast cancer may become the main trend and hotspot for ADCs indications in recent years.
    Conclusion: Antibody-drug conjugates have become the focus of targeted therapies in the field of oncology. The innovation of technology and combination application strategy will become the main trend and hotspots in the future.
    Keywords:  CiteSpace; Web of Science; antibody-drug conjugates; clinical trials; research trends
    DOI:  https://doi.org/10.3389/fonc.2022.1039882
  68. Front Psychol. 2022 ;13 1061989
    Bibliometric analyses of social media for educational purposes over four decades.
    Zhonggen Yu, Paisan Sukjairungwattana, Wei Xu.
      The unexpected outbreak of COVID-19 pandemic has led students to frequently use social media to receive education, which brought about both positive and negative learning outcomes (Oliveira et al., 2022). To address the issue of integrating social media into education, this study conducted both quantitative and qualitative studies using VOSviewer and CitNetExplorer. The qualitative study through CitNetExplorer, involving 1780 publications, concluded that while social media might have gained popularity in education based on the classic theoretical framework of the zone of proximal development, there might be many challenges such as teacher resistance, data privacy, costs, and ethical and social issues. Besides, this study conducted bibliometric analyses using VOSviewer (N = 1841) to identify the top cited authors, organizations, documents, references, sources, countries, and keywords with high occurrences based on the citation networks. In the future, researchers could enhance the studies on how to guide students and teachers to properly integrate social media into education.
    Keywords:  bibliometric analysis; challenges; education; educational outcomes; social media
    DOI:  https://doi.org/10.3389/fpsyg.2022.1061989
  69. BMC Med Educ. 2023 Jan 27. 23(1): 68
    Gender differences and cooperation in medical authorships - an analysis of the recent ten years in five key medical disciplines.
    Jin Yamamura, Isabel Molwitz, Ann-Kathrin Ozga, Thai-An Nguyen, Ilka Wedekind, Liesa Wolf-Baldauf, Minobu Kamo, Jing Zhao, Elif Can, Sarah Keller.
       BACKGROUND: Career prospects in academic medicine are strongly linked to scientific authorship and this marker has been widely used as an indicator of gender equity in academia. However, direct comparisons of medical disciplines regarding their proportion of female physicians (FP) in different countries are missing. This study examines the gender parity and gender cooperation using first authorships (FA) and senior authorships (SA) of scientific publications in five medical disciplines and six different OECD countries over a 10-year time-trend.
    METHODS: Articles from three high-impact journals in each of the medical discipline radiology, urology, surgery, gynecology, and pediatrics from the years 2007/8 and 2017/18 were retrospectively reviewed. The gender and affiliation location of the FA and SA of original research articles and reviews were assigned and compared with the proportion of in each discipline for the United States of America, Canada, United Kingdom, France, Germany, and Japan. Mantel-Haenszel test and multinomial logistic regression models were used to calculate differences in proportions of women authors and FP and to assess trends and proportions of FA and SA.
    RESULTS: 30,803 articles were evaluated. Equally, with rising proportions of FP in all disciplines, the number of women authors increased across years. The shares of women FAs were either significantly higher (urology/surgery/gynecology) or balanced (pediatrics/radiology) compared to the proportion of FP. In contrast, the shares of women SA were balanced only in disciplines with a low proportion of FP (urology and surgery) and otherwise reduced. Women same-gender cooperation was as common as men same-gender cooperation and preferred over a women-led mixed gender cooperation in disciplines where this seemed to be practicable due to the high proportions of FP.
    CONCLUSION: In contrast to FA, a significant disparity persists in SA, particularly in disciplines with a high proportion of FP. The discrepancy between FA and SA may reflect, among others, dropout from an academic career in early or mid-academic levels, for example, due to structural inequality; together with the findings on gender preference in authorship collaborations, this may inform future strategies for promoting equal career advancement for women physicians.
    Keywords:  Authorship; Career; Gender; Impact; Women
    DOI:  https://doi.org/10.1186/s12909-023-04041-6
  70. Rev Soc Bras Med Trop. 2023 ;pii: S0037-86822023000100306. [Epub ahead of print]56
    Scientometric review of research on Neglected Tropical Diseases: a 31-year perspective from the Journal of the Brazilian Society of Tropical Medicine.
    Anderson Fuentes Ferreira, Jorg Heukelbach, Carlos Henrique Nery Costa, Eliana Amorim de Souza, Adjoane Maurício Silva Maciel, Dalmo Correia, Alberto Novaes Ramos.
       BACKGROUND: To analyze the temporal evolution of research on Neglected Tropical Diseases (NTDs) published by the Journal of the Brazilian Society of Tropical Medicine (JBSTM).
    METHODS: We performed an analysis of the scientific production in JBSTM on NTDs using an advanced search, which included authors' descriptors, title, and abstract, and by combining specific terms for each NTDs from 1991 to 2021. Data related to authors, countries of origin, institutions, and descriptors, were evaluated and analyzed over time. Bibliographic networks were constructed using VOSviewer 1.6.16.
    RESULTS: The JBSTM published 4,268 scientific papers during this period. Of these 1,849 (43.3%) were related to NTDs. The number of publications on NTDs increased by approximately 2.4-fold, from 352 (total 724) during 1991-2000 to 841 (total 2,128) during 2011-2021, despite the proportional reduction (48.6% versus 39.5%). The most common singular NTDs subject of publications included Chagas disease (31.4%; 581/1,849), leishmaniasis (25.5%, 411/1,849), dengue (9.4%, 174/1,849), schistosomiasis (9.0%; 166/1,849), and leprosy (6.5%, 120/1,849), with authorship mostly from Brazil's South and Southeast regions.
    CONCLUSIONS: Despite the proportional reduction in publications, JBSTM remains an important vehicle for disseminating research on NTDs during this period. There is a need to strengthen the research and subsequent publications on specific NTDs. Institutions working and publishing on NTDs in the country were concentrated in the South and Southeast regions, requiring additional investments in institutions in other regions of the country.
    DOI:  https://doi.org/10.1590/0037-8682-0403-2022
  71. Front Oncol. 2022 ;12 1061324
    Corrigendum: Evolution of research trends in artificial intelligence for breast cancer diagnosis and prognosis over the past two decades: A bibliometric analysis.
    Asif Hassan Syed, Tabrej Khan.
      [This corrects the article DOI: 10.3389/fonc.2022.854927.].
    Keywords:  Bibliometrix analysis; artificial intelligence; breast cancer; diagnosis and prognosis; knowledge structures
    DOI:  https://doi.org/10.3389/fonc.2022.1061324
  72. J Cancer Policy. 2023 Jan 20. pii: S2213-5383(23)00022-X. [Epub ahead of print]35 100405
    Bibliometric analysis of cancer research outputs in Botswana between 2009 and 2021.
    Moses O Koobotse, Matshediso Zachariah, Bonolo Senabye, Irene Gobe, Khutsafalo Kadimo, Keneuoe C Nthontho, Margaret Mokomane, Garesego Koto, Thato Phuthego, Henry Lekgetho, Andrew Ndlovu, Modisa Motswaledi, Alfred Mbwinja, Leabaneng Tawe, Pleasure Ramatlho, Giacomo M Paganotti, Lynnete Kyokunda, Peter Vuylsteke, Surbhi Grover, Doreen Ramogola-Masire, Ishmael Kasvosve.
       INTRODUCTION: Cancer research is critical for cancer control policies; however, the state of cancer research activities in Botswana is largely unknown. The goal of this review was to describe trends and patterns of cancer research outputs in Botswana.
    METHODS: PubMed, Web of Science, EBSCOhost, African Journals Online, and African Index Medicus databases were systematically searched for peer-reviewed, primary cancer-related research articles published on the Botswana population or by Botswana institutions between January 2009 and June 2021.
    RESULTS: Of the 86 publications included, 39 (45 %) were about cervical cancer, followed by breast cancer (10 %) and Kaposi sarcoma (7 %). The remainder (27 %) were not focused on any specific cancer type. The research activities were skewed towards three main areas of scientific interest: early detection, diagnosis, and prognosis; cancer control, survivorship, and outcomes; and treatment. Botswana was represented by authors in the first (54 %), last (53 %), and any authorship (53 %) positions. The United States of America had the strongest collaborative partnerships with Botswana, followed by the United Kingdom and South Africa. The majority of funding institutions were American (76 %) and the National Institutes of Health was the most mentioned funding organization, accounting for 33 % of all financial acknowledgments. Only 9 % of the funding acknowledgments came from Botswana.
    CONCLUSION AND POLICY SUMMARY: Although cancer research in Botswana is expanding because of substantial foreign assistance, it is also hampered by a lack of local funding, minimal participation by Botswana-affiliated researchers, and research that is not aligned with disease burden. Our study highlights the need to strengthen local research capacity in Botswana.
    Keywords:  Bibliometrics; Botswana; Cancer; Research
    DOI:  https://doi.org/10.1016/j.jcpo.2023.100405
  73. J Vasc Surg. 2023 Jan 23. pii: S0741-5214(23)00264-1. [Epub ahead of print]
    An Analysis of Vascular Surgery Education Publications reveals an educational shortage.
    Rebecca N Treffalls, John A Treffalls, Nathalie S Barsoum, Niva Shrestha, Qi Yan, Mark G Davies.
       BACKGROUND: As vascular surgery training continues to evolve with the growth of integrated vascular surgery residency (0+5) programs and consolidation of fellowship programs, optimizing all aspects of the education for vascular surgery trainees, both fellows, and 0+5 residents, has become increasingly important. This study aimed to determine the prevalence, quality, and content of vascular surgery education publications across journals.
    METHODS: Journal websites (N=26) and PubMed were queried to identify vascular surgery education publications from 2012-2021. Publications were organized into 11 content categories: (1) Curriculum, (2) simulation, (3) trainee assessment, (4) program evaluation, (5) wellness/burnout, (6) diversity/inclusion, (7) mentorship/career, (8) case outcomes, (9) perceptions of training, (10) social media, and (11) other. Publication interactivity and quality were measured via PlumX data and Medical Education Research Study Quality Instrument (MERSQI) scores. Data were analyzed via univariate analysis and linear regressions.
    RESULTS: There were 115 identified vascular surgery education publications composing 0.2% (IQR 0.05) of total publications from selected journals. The Journal of Vascular Surgery had the highest proportion (0.8%) of vascular surgery education publications, followed by the Journal of Surgical Education (0.7%) and Annals of Vascular Surgery (0.6%). Vascular surgery journals composed a majority (79%) of the publications. Fifteen percent of authors (IQR 0-25) had master's or doctorate degrees in education. Senior authors were more often identified as male gender (77%), while more first authors (41%) were identified as female gender. Interactivity analysis showed that there were 10.3 (12) citations, 33.1 (IQR 34) captures, and 8.4 (IQR 14) social media interactions per publication. The educational quality had a median MERSQI score of 11 (IQR 9-12.5), with 49% of publications greater than the median score. Publications on training (44% curriculum and 20% simulation) were significantly more frequent compared to other topics (P<0.001), with no change in publication content over ten years (P=0.29). The volume of vascular surgery education publications did not change over the study period (P=0.13) despite the ongoing changes in the educational environment.
    CONCLUSION: Despite increasing importance placed on vascular surgery education by national vascular societies, publications on vascular surgery education remain sparse among all journals. Vascular surgery educational content has not changed over the last ten years, with a primary focus on curriculum and simulation training. Further promotion of vascular surgery educational research is required to increase the quality, volume, and diversity of education publications.
    Keywords:  Content; Educational Publications; Graduate Medical Education; Quality; Vascular Surgery
    DOI:  https://doi.org/10.1016/j.jvs.2022.12.066
  74. Work. 2023 Jan 19.
    Gender differences in academic productivity, educational positions, and leadership appointments of physicians in the U.S.
    Jennifer M V Talbott, Summer Ghaith, Darcy A Reed, Annie T Sadosty, Benjamin J Sandefur, Sharonne N Hayes, Michele Y Halyard, Lanyu Mi, Elisabeth S Lim, Rachel A Lindor.
       BACKGROUND: Promotions in academic medicine are frequently based on number of publications and leadership positions held. While prior study has established women publish less than men, many evaluations are limited to individual specialties and do not evaluate involvement with educational activities.
    OBJECTIVE: To compare gender differences in academic output, intramural leadership positions, and educational leadership positions of academic physicians.
    METHODS: The curriculum vitae and de-identified demographic data of all permanent physicians employed at a multi-site academic medical center were reviewed from April to May 2020. Multivariable logistic and Poisson regressions evaluated leadership positions and number of publications.
    RESULTS: Of 3,359 physicians in the demographic database, 32.3% (n = 1,087) were women and 72.5% were white (n = 2,510). Of the 3,015 physicians in the curriculum vitae database, 32% (n = 962) were women. Women were more likely (p < 0.001) to be assistant professor (54% vs. 42.7%) and less likely to be associate (18.1% vs. 20.3%) or full professor (14.6% vs. 29.1%). Women assistant professors published 22% fewer articles (ratio estimate = 0.78, p < 0.001), associate professors 18% less (coefficient = 0.82, p < 0.001), and full professors 23% less (coefficient = 0.77, p < 0.001). Fewer women were program directors for residencies (1.6% vs. 2.9%, p = 0.02) or fellowships (5.4% vs. 7.4%, p = 0.04), and held fewer division or department leadership positions (OR 0.8, 95% CI as [0.6, 1.0], p = 0.03).
    CONCLUSION: Women physicians do not outperform men across any education, leadership, or publication category. A cultural shift is needed to redefine traditional metrics for leadership appointments if academic medicine hopes to achieve equity.
    Keywords:  Gender equity; medicine; publications; sexism; women
    DOI:  https://doi.org/10.3233/WOR-220193
  75. Procedia Comput Sci. 2023 ;217 1887-1895
    Human Robot Collaboration in Industry 4.0: a literature review.
    Alessio Baratta, Antonio Cimino, Maria Grazia Gnoni, Francesco Longo.
      Technological developments through the fourth industrial revolution (Industry 4.0) jointly with the global COVID-19 pandemic have brought about a change in life and work of almost all existing professionals. Some researchers argue how the fifth industrial revolution will approach the fourth much sooner than all previous industrial revolutions. In fact, several sources start talking about the fifth industrial revolution, although the paradigms that will define its context and areas of development are still unclear. This research study focuses on one of the foundational aspects of the fourth industrial revolution and which already has the basis for being projected into the fifth industrial revolution and thus the possibility to be taken to the next level: Human-Robot Collaboration. A state-of-the-art study and a bibliometric analysis have been carried out in order to identify research trends related to this paradigm. In addition, the authors present a definition of HRC trying to describe its main characteristics and the key aspects that identify it. In the second part of the paper, a summary of the main research trends is presented, reporting some significant case studies.
    Keywords:  Human-Robot Collaboration; Industry 4.0.; bibliometric analysis
    DOI:  https://doi.org/10.1016/j.procs.2022.12.389
  76. Euro Surveill. 2023 Jan;28(2):
    Using the rear-view mirror to look forward.
    Eurosurveillance editorial team
      
    Keywords:  COVID-19; SARS-CoV-2; impact factor; metrics; peer reviewer
    DOI:  https://doi.org/10.2807/1560-7917.ES.2023.28.2.220112e
  77. Front Psychol. 2022 ;13 1018183
    Visual analysis of environmental research progress in Germany linking Development Anthropology: A sustainable approach based on the Web of Science.
    Wei Zong, Fei Wang, Bo Tu, Huazhong Tu, Hao Zhang, Chuke Wu, Muhammad Toseef.
      Environmental devaluation is a major concern for European countries as they seek to scrutinize strategies for development anthropology. Germany holds diversified ties with the socioeconomic and environmental development of the region. In accordance with global obligations, Germany's research on environmental issues, protection laws and actions, and universities and scientific research institutions in the field of environmental protection are progressing toward the development of a sustainable future securing the development anthropology. However, Germany's research on environmental issues is unclear to the rest of the world. Chinese scholars also lack effective countermeasures and suggestions for implementing environmental protection cooperation between China and Germany under the Belt and Road Initiative to draw a sustainable global drain. Understanding the current situation and frontier trend of environmental research in German academic circles is essential and irreplaceable for relying on research results data and quantitative analysis theory to carry out the research process. The methodology of this paper established a quantitative analysis based on "institutions," "scholars," "research objects," and "frequency of keywords" among the research results on environmental issues in Germany. It constructs a digital portrait of the field of environmental research in Germany. Knowledge mapping is extensively used in this study as the primary research tool to show the development of environmental research in Germany. The standard deviation of social science research has roughly doubled in that time. CiteSpace, a visual tool for document statistical analysis, is used to analyze the research results on environmental protection published by German scholars from 2008 to 2018. The study results include Web of Science Network, and finally, a visual map is drawn. This study analyzes the status quo, research institutions, keywords, research hotspots, and research trends of international cooperation in environmental research in Germany. The findings are in supportive position of environment study that is the key to human existence and societal development. Leading to this Germans are in concern of human anthropology being reflected in scholarly published work. In response to practical challenges, "global warming" and "sustainable development" became the most frequently used keywords. It provides sustainable thoughts and countermeasures to strengthen Sino-German environmental protection exchange and cooperation further.
    Keywords:  Belt and Road; Germany; development anthropology; economic growth; sustainable environmental; sustainable thoughts
    DOI:  https://doi.org/10.3389/fpsyg.2022.1018183
  78. Vascular. 2023 Jan 28. 17085381231154343
    Panel composition and disparities in the topics of presentation in vascular surgery conferences.
    Utsav Soni, John Phair, Leo Zekelman, Smita Mascharak, Krystina Choinski, Evan Lipsitz, Issam Koleilat.
       BACKGROUND: Previous studies identified gender disparities in surgical conference presenters and moderators. We sought to assess disparities in the representation of women in terms of speakers and moderators, but with particular emphasis on panels and topics of discussion at vascular surgery conferences.
    METHODS: Data regarding presenters and moderators from the Southern Association of Vascular Surgery, Western Vascular Society, Vascular and Endovascular Surgical Society, Society for Clinical Vascular Surgery, and Society for Vascular Surgery conferences was obtained from online meeting archives and via email correspondence. Scientific session speakers, moderators, and panelists were identified by sex. Specific vascular topics for each discussion were also identified. Keynote speakers or special guests were excluded.
    RESULTS: Compared to men, women were less often presenters (18% versus 82%, p < .002) and moderators (16% versus 84%, p < .001) of conference sessions. Women were most likely to present on dialysis access and least likely to present on venous disease overall. Women were more likely to present on aortic (24% vs 19%; p < .013) and cerebrovascular disease (33% vs 27%; p < .021) at regional compared to national conferences. Of panels assessed, 68% were all-male. Subgroup analysis suggests that some improvements have been made over time.
    CONCLUSIONS: Significant disparities persist in the topics presented and in panel composition suggesting potential areas for improvement in equity. Further study should focus on evaluating trends in the training level of the presenter and the topics presented, and assessing parity in structural factors that impact research presentation opportunities.
    Keywords:  Women; conferences; manel; panel; topics; vascular surgery
    DOI:  https://doi.org/10.1177/17085381231154343
  79. Ann Thorac Surg. 2023 Jan 24. pii: S0003-4975(23)00040-1. [Epub ahead of print]
    Gender Disparities in Cardiac Surgery Trials: Leadership, Authorship, and Patient Enrollment.
    Giovanni Jr Soletti, Roberto Perezgrovas-Olaria, Arnaldo Dimagli, Lamia Harik, Lisa Rong, C Noel Bairey Merz, Mohamed Rahouma, Sigrid E Sandner, Annetine C Gelijns, Mario Gaudino.
       BACKGROUND: Studies have highlighted the paucity of women-led randomized controlled trials (RCTs) in cardiovascular medicine. Whether this finding also applies to cardiac surgery has not been evaluated. In this study, we evaluate women authorship, leadership, and women enrollment in cardiac surgery RCTs.
    METHODS: A systematic literature search was conducted to identify RCTs comparing two or more adult cardiac surgical procedures published from 2000 to 2022. Women-led RCTs were defined as those with a woman either as a first or last author. Linear regression and correlation analyses were used.
    RESULTS: Of fifty-eight RCTs, eight (13.8%) were women-led. Seventeen (29.3%) RCTs had no women authors. Overall, 17.9% of all authors were women, but only 1.2% of all authors were women cardiac surgeons and only 19% of the RCTs had a women cardiac surgeon among the authors. The median proportion of women authors was 14.3% by RCT, which was significantly higher in women- compared to men-led RCTs (28.6% vs 11.8%, P=0.01). No significant change in the proportion of women authors was observed over the study period. North American RCTs had a higher proportion of women authors compared to other geographical regions (28.6% vs 12.5%, P=0.01). No correlation was found between the proportion of women authors and the proportion of women participants enrolled in individual RCTs.
    CONCLUSIONS: Over the last two decades, only a minority of cardiac surgery RCTs were women-led and no significant increase in women authorship occurred. There are important geographical differences in women authorship.
    DOI:  https://doi.org/10.1016/j.athoracsur.2023.01.022
  80. BMJ Open. 2022 Sep 02. 12(9): e052891corr1
    Correction: Citation impact and social media visibility of Great Barrington and John Snow signatories for COVID-19 strategy.
      
    DOI:  https://doi.org/10.1136/bmjopen-2021-052891corr1
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