bims-evares Biomed News
on Evaluation of research
Issue of 2022‒12‒04
sixty-two papers selected by
Thomas Krichel
Open Library Society
  1. Top 50 Most Cited Articles About OAB: A Bibliometric Analysis.
  2. Global trends and prospects in research of artificial cornea over past 20 years: a bibliometric and visualized analysis.
  3. Research landscape and trends of lung cancer radiotherapy: A bibliometric analysis.
  4. One hundred most cited articles related to Endoscopic retrograde cholangiopancreatography: A bibliometric analysis.
  5. Knowledge atlas and emerging trends on ncRNAs of osteosarcoma: A bibliometric analysis.
  6. Intellectual disability and COVID-19: A bibliometric review.
  7. The scientific progress and prospects of artificial intelligence in digestive endoscopy: A comprehensive bibliometric analysis.
  8. Characteristics and trends in acceptance and commitment therapy research: A bibliometric analysis.
  9. Scientific authorship in neurosurgery.
  10. The 100 most cited articles in peri-implant diseases. A bibliometric study of the web of science.
  11. Cerebellar Liponeurocytoma: Publication Trends, Scientometrics Analysis, and Critical Review.
  12. Virtual reality for neurorehabilitation: A bibliometric analysis of knowledge structure and theme trends.
  13. Global trends and hotspots in research of robotic surgery in oncology: A bibliometric and visual analysis from 2002 to 2021.
  14. Top 100 most-cited articles on hemorrhoids: A bibliometric analysis and visualized study.
  15. Bibliometric Analysis of Indian Journal of Palliative Care from 1995 to 2022 using the VOSviewer and Bibliometrix Software.
  16. Psychological capital in university students: analysis of scientific activity in the scopus database.
  17. Pandemic Critical Care Research during the COVID-19 (2020-2022): A Bibliometric Analysis Using VOSviewer.
  18. The global research of bladder cancer immunotherapy from 2012 to 2021: A bibliometric analysis.
  19. Artificial Intelligence in Intensive Care Medicine: Bibliometric Analysis.
  20. Global trends and Frontier topics about vascular smooth muscle cells phenotype switch: A bibliometric analysis from 1999 to 2021.
  21. Suicide and suicidal ideation in the times of the Covid-19 pandemic: A scientometric analysis.
  22. Hyperbaric oxygen therapy research: an analysis of the 100 most-cited publications from 2011 to 2020.
  23. Demoralization: Where it stands-and where we can take it: A bibliometric analysis.
  24. A bibliometric and visual analysis of contaminant transport modeling in the groundwater system: current trends, hotspots, and future directions.
  25. Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021.
  26. A bibliometric analysis of the recent advances in diazepam from 2012 to 2021.
  27. Research on application of tumor treating fields in glioblastoma: A bibliometric and visual analysis.
  28. Bibliometric and visual analysis of coronary microvascular dysfunction.
  29. Mapping the trends and impact of research collaboration between countries in oral implantology publications: A bibliometric analysis from 1999 to 2019.
  30. Association between electroconvulsive therapy and depressive disorder from 2012 to 2021: Bibliometric analysis and global trends.
  31. Research trends in social media addiction and problematic social media use: A bibliometric analysis.
  32. Worldwide productivity and research trends of publications concerning stent application in acutely ruptured intracranial aneurysms: A bibliometric study.
  33. A Scientometric Analysis of Studies on Patellar Dislocation.
  34. Global trends in Akkermansia muciniphila research: A bibliometric visualization.
  35. A bibliometric and visualization-based analysis of temozolomide research hotspots and frontier evolution.
  36. The Great Inflation: How COVID-19 affected the Journal Impact Factor of high impact medical journals.
  37. Emerging trends in epigenetic and childhood trauma: Bibliometrics and visual analysis.
  38. A Bibliometric and Visualized Analysis of Liver Fibrosis From 2002 to 2022.
  39. Trends in research on sick sinus syndrome: A bibliometric analysis from 2000 to 2022.
  40. The schizophrenia and gut microbiota: A bibliometric and visual analysis.
  41. The 50 most impactful articles on the medial ulnar collateral ligament: An altmetric analysis of online media.
  42. Trends in dithiocarbamates food research: A bibliometric vision.
  43. Advances in research on schistosomiasis and toxoplasmosis in China: a bibliometric analysis of Chinese academic journals published from 1980 to 2021.
  44. Bibliometric and visual analysis in the field of ketogenic diet on cancer from 2012 to 2021.
  45. The Circulation Journal Official Impact Factor and the Most Frequently Cited Papers in 2021.
  46. Retracted papers originating from paper mills: cross sectional study.
  47. Exosome-Based Therapy for Ischemic Stroke: A Bibliometric Analysis of Current Trends and Future Directions.
  48. Plant responses to high temperature and drought: A bibliometrics analysis.
  49. Trends in gender of first and senior authors of articles published in JMIRO.
  50. Bibliometric and visual analysis of fecal microbiota transplantation research from 2012 to 2021.
  51. Gender disparity in academic advancement: exploring differences among adult and pediatric radiologists.
  52. Global Analyses and Latest Research Hot Spots of Adipose-Derived Stem Cells in Fat Grafting: A Bibliometric and Visualized Review.
  53. LDA-based topic modeling for COVID-19-related sports research trends.
  54. COVID-19 and finance scholarship: A systematic and bibliometric analysis.
  55. A Bibliometric Review: Brain Tumour MRIs using different CNN Architectures.
  56. Comment on "research on the remediation of cesium pollution by adsorption: Insights from bibliometric analysis".
  57. Effects of mitochondrial dysfunction on bone metabolism and related diseases: a scientometric study from 2003 to 2022.
  58. Current research topics in FAPI theranostics: a bibliometric analysis.
  59. TELS: Evolution patterns of research keywords from the evidence of PNAS Social Sciences topics.
  60. Diverse roles of the CIPK gene family in transcription regulation and various biotic and abiotic stresses: A literature review and bibliometric study.
  61. Trends in country and gender representation on editorial boards in anaesthesia journals: a pooled cross-sectional analysis.
  62. An exploratory study of citations in systematic reviews of randomized trials published in Latin American journals.
  1. Urology. 2022 Nov 23. pii: S0090-4295(22)00974-8. [Epub ahead of print]
    Top 50 Most Cited Articles About OAB: A Bibliometric Analysis.
    Susan Gong, Fred Gong, Abdo Kabarriti.
      OBJECTIVE: To identify key articles about OAB using citation number and bibliometric analysis.METHODS: We searched for articles in the Web of Science Core Collection between 1900 and 2022 using terms specific to OAB. We identified relevant OAB articles and selected the top 50 most cited. A bibliometric analysis was performed to collect and analyze data about authorship, title, publication year, total citations, journal, journal impact factor, country, institution, study type, citation index, conflict of interest (COI), and conclusions.
    RESULTS: A total of 12,200 records were identified. The top 50 most cited articles were published between 1997-2015 in nine countries, across over 30 different institutions, and in 19 journals. The country, institution, and journal which produced the greatest number of articles were the USA, Southmead General Hospital in England, and BJU International, respectively. The mean number of citations per article was 365.66. Observational studies and clinical trials were the most common. Most articles were published in 2006 and were sponsored. The most cited article also had the most citations per year. This study is limited by using a single database and a single parameter as a proxy for paper importance.
    CONCLUSION: Bibliometric analyses are an important resource for clinicians to understand the body of knowledge of OAB by identifying landmark papers. This objective approach to literature review can facilitate future research and scholarly efforts.
    Keywords:  OAB, bibliometric analysis; top cited articles; urology
    DOI:  https://doi.org/10.1016/j.urology.2022.09.038
  2. Int Ophthalmol. 2022 Nov 27.
    Global trends and prospects in research of artificial cornea over past 20 years: a bibliometric and visualized analysis.
    Youran Cai, Jiaxin Zhou, Xuyang Xu, Bingbing He, Wenjin Zou.
      BACKGROUND: Many studies have been focused on the area of the artificial cornea. In our study, a bibliometric analysis was performed on the artificial cornea to identify the global key research fields and trends over the past 20 years.METHODS: Publications about artificial cornea were retrieved and downloaded from the Web of Science Core Collection from 2002 to 2021. CiteSpace and VOSviewer were used to analyze countries, institutions, authors, and related research areas.
    RESULTS: A total of 829 eligible publications were analyzed. The USA was the most productive country for the artificial cornea, followed by China and Canada. Harvard University was the most prolific institution in this field. Cornea published most of the studies in this area and Dohlman CH was the most cited author.
    CONCLUSIONS: Bibliometric analysis in our study first provides a general perspective on the artificial cornea, which can be helpful to further explore the issues in the rapidly developing area.
    Keywords:  Artificial cornea; Bibliometric analysis; CiteSpace; Publication; VOSviewer
    DOI:  https://doi.org/10.1007/s10792-022-02600-2
  3. Front Oncol. 2022 ;12 1066557
    Research landscape and trends of lung cancer radiotherapy: A bibliometric analysis.
    Yanhao Liu, Shu Jiang, Yaru Lin, Haiming Yu, Lan Yu, Xiaotao Zhang.
      Background: radiotherapy is one of the major treatments for lung cancer and has been a hot research area for years. This bibliometric analysis aims to present the research trends on lung cancer radiotherapy.Method: On August 31, 2022, the authors identified 9868 articles on lung cancer radiotherapy by the Web of Science (Science Citation Indexing Expanded database) and extracted their general information and the total number of citations. A bibliometric analysis was carried out to present the research landscape, demonstrate the research trends, and determine the most cited papers (top-papers) as well as top-journals on lung cancer radiotherapy. After that, the authors analyzed the recent research hotspots based on the latest publications in top-journals.
    Results: These 9868 papers were cited a total of 268,068 times. "Durvalumab after chemoradiotherapy in stage III non-small-cell lung cancer" published in 2017 by Antonia et al.was the most cited article (2110 citations). Among the journals, New England Journal of Medicine was most influential. Moreover, J. Clin. Oncol. and Int. J. Radiat. Oncol. Biol. Phys. was both influential and productive. Corresponding authors represented the USA (2610 articles) and China mainland (2060 articles) took part in most publications and articles with corresponding authors from Netherlands were most cited (46.12 citations per paper). Chemoradiotherapy was the hottest research area, and stereotactic body radiotherapy has become a research hotspot since 2006. Radiotherapy plus immunotherapy has been highly focused since 2019.
    Conclusions: This bibliometric analysis comprehensively and quantitatively presents the research trends and hotspots based on 9868 relevant articles, and further suggests future research directions. The researchers can benefit in selecting journals and in finding potential collaborators. This study can help researchers gain a comprehensive picture of the research landscape, historical development, and recent hotspots in lung cancer radiotherapy and can provide inspiration for future research.
    Keywords:  SAbR; SBRT; bibliometric analysis; chemoradiotherapy; chemotherapy; immunotherapy; lung cancer; radiotherapy
    DOI:  https://doi.org/10.3389/fonc.2022.1066557
  4. Front Surg. 2022 ;9 1005771
    One hundred most cited articles related to Endoscopic retrograde cholangiopancreatography: A bibliometric analysis.
    Xuan Xu, Lulu Guan, Yao Wu, Huajing Ke, Yuanbin Zhao, Pi Liu.
      Background: Endoscopic retrograde cholangiopancreatography (ERCP) has developed over the past few decades into a reliable technology for diagnostic and therapeutic purposes. Through a bibliometric analysis, this research attempted to evaluate the characteristics of the top 100 articles on ERCP that had the most citations.Methods: We extracted pertinent publications from the Web of Science Core Collection (WoSCC) on July 9, 2022. The top 100 ERCP articles with the most citations were identified and analyzed. The following data were extracted: publication year, country/region, organization, total citation times, annual citation times, research type and research field, etc. To implement the network's visual analysis, a bibliographic coupling network based on keywords was built using the VOSviewer 1.6.17 program.
    Results: The journal with the most publications were GASTROINTESTINAL ENDOSCOPY, with 45 articles. Most of the top 100 articles came from the United States (n = 47) and Italy (n = 14). Indiana University and the University of Amsterdam were among the most important institutions in ERCP research. ML Freeman of the University of Minnesota contributed the highest number (n = 9) and the most highly cited paper. The age of the paper and article type is closely related to citation frequency. Of the 100 most-cited articles, clinical application in the field of ERCP has focused on three aspects: diagnosis, treatment, and complications. Clinical use of ERCP has shifted from diagnosis to treatment. Post-ERCP pancreatitis is the focus of attention, and the clinical application of technically complex therapeutic ERCP is the future development trend.
    Conclusion: This study lists the most influential articles in ERCP by exposing the current state of the field, and showing the evolution of research trends to provide perspective for the future development of ERCP.
    Keywords:  ERCP; bibliometric analysis; post-ERCP pancreatitis; top-cited; visualization
    DOI:  https://doi.org/10.3389/fsurg.2022.1005771
  5. Front Endocrinol (Lausanne). 2022 ;13 1028031
    Knowledge atlas and emerging trends on ncRNAs of osteosarcoma: A bibliometric analysis.
    Bo Wang, Chunhua Yang, Chuqiao Zhou, Shipeng Xiao, Hui Li.
      Background: Osteosarcoma is a common bone sarcoma that occurs in childhood and adolescence. Although research on non-coding RNAs (ncRNAs) of osteosarcoma has been developed rapidly in recent years, a specific bibliometric analysis on this topic has not yet been performed. The bibliometric analysis aims to summarize knowledge atlas, research hotspots, and emerging trends and to provide researchers with new perspectives in further studies.Methods: All publications regarding ncRNAs of osteosarcoma published from 2000 to 2021 were retrieved from the Web of Science Core Collection. Quantitative indicators including the number of publications and citations, H-index, and journal citation reports were analyzed by using Excel 2019 and R software. VOSviewer and CiteSpace were used to analyze the cooperation among countries/institutions/journals/authors and the co-occurrence of keywords, keywords bursts, and references.
    Results: A total of 3206 publications were extracted. A significant growth trend in the annual number of publications over the past 22 years is revealed (R 2 = 0.999). The most prolific country and institution were China (2260) and Shanghai Jiao Tong University (134), respectively. Professors Wang W and Liu W contributed the most to this field. The keywords were stratified into six clusters: Cluster 1 (apoptosis and growth), Cluster 2 (cancer and progression), Cluster 3 (microRNAs and downregulation), Cluster 4 (genes and differentiation), Cluster 5 (expression and biological functions), and Cluster 6 (metastasis). The long non-coding RNAs and circular RNAs have been considered as an important research hotspot in the near future.
    Conclusion: This study offers a scientific perspective on ncRNAs of osteosarcoma and provides researchers with valuable information to understand the knowledge structure and to identify emerging trends in this field.
    Keywords:  Citespace; VOSviewer; bibliometric analysis; non-coding RNAs; osteosarcoma
    DOI:  https://doi.org/10.3389/fendo.2022.1028031
  6. Front Psychiatry. 2022 ;13 1052929
    Intellectual disability and COVID-19: A bibliometric review.
    Jiangbo Ying, Giles Ming Yee Tan, Melvyn Weibin Zhang.
      Background: During the COVID-19 pandemic, the vulnerabilities of certain groups of people have been highlighted, such as people with intellectual disability (ID). Although related research on ID has developed rapidly during the COVID-19 pandemic, the quantitative analysis of those research results has not been systematically performed through bibliometric analysis. Bibliometric analysis is a useful and rigorous method to explore large volumes of research data, and it allows researchers to extract quantitative information on distribution by author, time, country, and journal.Aim: The aim of the present study is to comprehensively analyze the current status and developing trends in publications on ID research related to and conducted during the COVID-19 pandemic.
    Methods: A bibliometric analysis was performed using the Web of Science database. Biblioshiny software was used to analyze and visualize the following information: main information of dataset, annual scientific production, journals which published the most relevant sources, most-cited authors, most-cited countries, most-cited global documents, word-cloud of keywords authors have used, and both the co-occurrence and co-citation networks.
    Results: A total of 450 publications were included. The average number of citations per document was 5.104. Among the top three journals, Journal of Applied Research in Intellectual Disabilities published 32 articles, Journal of Intellectual Disability Research published 29 articles, and British Journal of Learning Disabilities published 17 articles. The article with the title COVID-19 and People with Intellectual Disability: Impact of a Pandemic was the most cited with total 144 citations The United Kingdom had the most publications and had strong cooperative relationships with the United States, Canada, and Australia. The most popular keywords included mental health, autism, developmental disability, and lockdown. Thematic map analysis identified several possible clusters, including telemedicine, physical activities, and mental health.
    Conclusion: The present study provides a better understanding in this research field and may help clinicians, researchers and stakeholders to obtain more comprehensive view of ID and COVID-19. The insights gained from this analysis could inform future research.
    Keywords:  COVID-19; bibliometric analysis; intellectual disability; research trends; scientific collaboration
    DOI:  https://doi.org/10.3389/fpsyt.2022.1052929
  7. Medicine (Baltimore). 2022 Nov 25. 101(47): e31931
    The scientific progress and prospects of artificial intelligence in digestive endoscopy: A comprehensive bibliometric analysis.
    Pei-Ling Gan, Shu Huang, Xiao Pan, Hui-Fang Xia, Mu-Han Lü, Xian Zhou, Xiao-Wei Tang.
      BACKGROUND: Artificial intelligence (AI) has been used for diagnosis and outcome prediction in clinical practice. Furthermore, AI in digestive endoscopy has attracted much attention and shown promising and stimulating results. This study aimed to determine the development trends and research hotspots of AI in digestive endoscopy by visualizing articles. Publications on AI in digestive endoscopy research were retrieved from the Web of Science Core Collection on April 25, 2022. VOSviewer and CiteSpace were used to assess and plot the research outputs. This analytical research was based on original articles and reviews. A total of 524 records of AI research in digestive endoscopy, published between 2005 and 2022, were retrieved. The number of articles has increased 27-fold from 2017 to 2021. Fifty-one countries and 994 institutions contributed to all publications. Asian countries had the highest number of publications. China, the USA, and Japan were consistently the leading driving forces and mainly contributed (26%, 21%, and 14.31%, respectively). With a solid academic reputation in this area, Japan has the highest number of citations per article. Tada Tomohiro published the most articles and received the most citations.. Gastrointestinal endoscopy published the largest number of publications, and 4 of the top 10 cited papers were published in this journal. "The Classification," "ulcerative colitis," "capsule endoscopy," "polyp detection," and "early gastric cancer" were the leading research hotspots. Our study provides systematic elaboration for researchers to better understand the development of AI in gastrointestinal endoscopy.
    DOI:  https://doi.org/10.1097/MD.0000000000031931
  8. Front Psychol. 2022 ;13 980848
    Characteristics and trends in acceptance and commitment therapy research: A bibliometric analysis.
    Zhihong Li, Wenru Shang, Caiyun Wang, Kehu Yang, Juanmei Guo.
      Purpose: As acceptance and commitment therapy (ACT) becomes mainstream and a growing body of literature emerges, it is critical to map the global collaborative network and a quantitative and systematic assessment of ACT, as research on this topic is still lacking. This review aims to provide a comprehensive understanding of the trajectory, key themes, and future prospects in ACT research.Methods: Publications were extracted from the Web of Science Core Collection before 2022. Excel 2019, VOSviewer, and CiteSpace software were used to analyze the characteristics and trends of ACT research. Examples include publications trend analysis, authors' cooperation network analysis, keywords co-occurrence analysis, and citation burst analysis.
    Results: A total of 799 articles in 314 journals contributed by 2,862 authors from 958 institutions in 52 countries were identified. The number of publications has increased significantly since 2015. The United States/Utah State University is the most productive country/institution; Karolinska Institute, Utah State University, and King's College of London are the most significant nodes. Twohig M.P., Hayes S.C., and Levin M.E. are the most influential authors. Keyword co-occurrence analysis found the curative mechanisms, using network technology or mobile technology as adjuvant therapy, reducing psychological diseases of cancer patients were potential trends.
    Conclusion: This review is the first attempt of its kind to systematically examine the knowledge structure and draw an evidence map of ACT research. It deepens the understanding of existing research, gives many operable research directions and suggests to future ACT research.
    Keywords:  acceptance and commitment therapy; anxiety; bibliometric analysis; depression; knowledge map; research trends
    DOI:  https://doi.org/10.3389/fpsyg.2022.980848
  9. Neurocirugia (Astur : Engl Ed). 2022 Nov 28. pii: S2529-8496(22)00077-6. [Epub ahead of print]
    Scientific authorship in neurosurgery.
    Rubén Diana-Martín, Pedro David Delgado-López.
      INTRODUCTION: Assessment of scientific bibliographic production is a complex issue, mainly based on the impact factor (IF) of the journals and the h index, that quantifies the number of cites an author receives. In order to estimate the bibliographic production and the influence of co-authorship among Spanish neurosurgeons, we performed a PubMed search aimed to identify all papers published by a sample of neurosurgeons.METHODS: Cross-sectional observational and regional study. We identified a sample of 183 neurosurgeons from Madrid and Castilla y León Autonomous Communities. The bibliometric information was gathered in March 2022 via PubMed free access website. For each author we registered the type of journal, total number of articles, order of appearance in the authors' list, total IF, the proportion of articles signed as first or second author (Personal Authorship Quotient [PAQ]) and the percentage of IF attributable to those articles (Personal Impact Quotient [PIQ]).
    RESULTS: A total of 3,592 articles from 183 authors were published in 412 different journals, of which only 9.9% were pure neurosurgical journals. Only 17 neurosurgeons (9,3%) had published at least one article as unique author. The average number of articles per neurosurgeon was 20 (median 9) of which 57.7% were published in neurosurgical journals, and 22,2% in Neurocirugía (official publication of the SENEC). The average PAQ was 0.367 (median 0.364) and the average PIQ was 0.317 (median 0.251). Both proportions tended to decrease as the number of publications increased.
    CONCLUSIONS: On average, Spanish neurosurgeons publish half of their articles in neurosurgical journals, appear as first or second author in one third of the cases, and the IF attributable to these papers comprise 25% of the total IF. The PAQ and PIQ provide bibliometric information that minimizes the enlarging effect on curriculum of massive co-authorship and allow comparisons among authors and different scientific fields.
    Keywords:  Article; Artículo.; Authorship; Autoría; Bibliometrics; Bibliometría; Factor de impacto; Impact factor; Manuscript; Manuscrito; Neurocirugía; Neurosurgery
    DOI:  https://doi.org/10.1016/j.neucie.2022.11.007
  10. J Clin Exp Dent. 2022 Nov;14(11): e920-e925
    The 100 most cited articles in peri-implant diseases. A bibliometric study of the web of science.
    Andrés López-Roldán, Beatriz Tarazona-Álvarez, Antonio Vidal-Infer, Adolfo Alonso-Arroyo.
      Background: The purpose of the study was to analyze the 100 most-cited articles on peri-implantitis pathology in the Web of Science database.Material and Methods: The articles were selected from all categories of the Web of Science, to consider all variations and synonyms of peri-implant disease. Articles were reviewed for typographical, transcription, and indexing errors.
    Results: The top 100 most-cited articles were published from 1994 to 2018, and had a total of 24,103 citations; 53 of the studies were funded. In total, 274 authors contributed to the papers, 5 of whom contributed to 10 or more articles. Review (n = 47) and clinical (n = 45) articles were the most prevalent types. European public universities made the largest contribution to the literature, and Sweden and Switzerland were the most active countries. All of the articles were published in 12 high-impact-factor journals.
    Conclusions: This is the first analysis of the most-cited articles on periimplantitis published in the Web of Science. In this bibliometric analysis, the most cited articles were published in high-impact-factor journals and were predominantly review articles. The most-cited authors are also active in other scientific disciplines such as periodontics. Key words:Dental implantation, Dental implants, Peri-implantitis, Mucositis.
    DOI:  https://doi.org/10.4317/jced.59786
  11. World Neurosurg. 2022 Nov 29. pii: S1878-8750(22)01650-3. [Epub ahead of print]
    Cerebellar Liponeurocytoma: Publication Trends, Scientometrics Analysis, and Critical Review.
    Rabia Ali, Sulaman Durrani, Karim Rizwan Nathani, Ryan Jarrah, Mohamad Bydon.
      BACKGROUND: The literature on cerebellar liponeurocytoma (CL) has never been systematically assessed using bibliometric analytic methodologies. We quantitatively analyzed the major trends and scientific output regarding CL, highlighting potential avenues for research.METHODS: Elsevier's Scopus database was used to collect all published studies relevant to Cerebellar Liponeurocytoma from 1978 to 2021. The specific bibliometric parameters were extracted and analyzed with R v4.1.2.
    RESULTS: Our search yielded 108 documents published in 67 sources from 1978 to 2021. The annual growth rate of publications regarding CL has been 7.47% per year since 1978. Journals with the most publications on CL include Clinical Neuropathology and Neurology India (n=5), followed by Acta Neuropathologica and Journal of Neuro-oncology (n=4). A total of 529 authors have published on CL and they have been cited 598 times. The ten most influential authors in the field were determined using their total number of citations and the local H-index. Kleihues P has the highest number of citations (n=177) with a local H index of 3, followed by Chimelli L with 167 citations and a local H index of 4. Davis DG has 149 citations and a local H index of 3. China had the most single country publications (SCPs) followed by India, Italy, and the USA. France and Austria have the most multiple country publications (MCPs) followed by China, Tunisia, Brazil, United Kingdom, Egypt, and Israel.
    CONCLUSION: Our study is the first bibliometric analysis evaluating the present literature and publication trends in CL. Generally, the current literature has a few studies regarding CL relative to other neuro-oncological pathologies. This can be due to the low incidence of the disease and highlights a need for high volume database studies that can offer high quality evidence on the subject.
    Keywords:  Cerebellar liponeurocytoma; bibliometric analysis; lipomatous medulloblastoma; liponeurocytoma
    DOI:  https://doi.org/10.1016/j.wneu.2022.11.098
  12. Front Public Health. 2022 ;10 1042618
    Virtual reality for neurorehabilitation: A bibliometric analysis of knowledge structure and theme trends.
    Qi-Fan Guo, Lin He, Wei Su, Hui-Xin Tan, Lian-Yi Han, Chen-Fan Gui, Yi Chen, Han-Hong Jiang, Qiang Gao.
      Background: As an emerging technology, virtual reality (VR) has been broadly applied in the medical field, especially in neurorehabilitation. The growing application of VR therapy promotes an increasing amount of clinical studies. In this paper, we present a bibliometric analysis of the existing studies to reveal the current research hotspots and guide future research directions.Methods: Articles and reviews on the related topic were retrieved from the Science Citation Index Expanded of Web of Science Core Collection database. VOSviewer and Citespace software were applied to systematically analyze information about publications, countries, institutions, authors, journals, citations, and keywords from the included studies.
    Results: A total of 1,556 papers published between 1995 and 2021 were identified. The annual number of papers increased gradually over the past three decades, with a peak publication year in 2021 (n = 276). Countries and institutions from North America and Western European were playing leading roles in publications and total citations. Current hotspots were focused on the effectiveness of VR therapy in cognitive and upper limb motor rehabilitation. The clusters of keywords contained the four targeted neurological diseases of VR, while the burst keywords represented that the latest studies were directed toward more defined types of VR therapy and greater study design.
    Conclusions: Our study offers information regarding to the current hotspots and emerging trends in the VR for rehabilitation field. It could guide future research and application of VR therapy in neurorehabilitation.
    Keywords:  bibliometric; hotspots; neurorehabilitation; research trends; virtual reality
    DOI:  https://doi.org/10.3389/fpubh.2022.1042618
  13. Front Oncol. 2022 ;12 1055118
    Global trends and hotspots in research of robotic surgery in oncology: A bibliometric and visual analysis from 2002 to 2021.
    Hua Lu, Tingliang Han, Fangcun Li, Jiali Yang, Zhaomeng Hou.
      Background: With the development of robotic surgery in the field of oncology, an increasing number of relevant research papers have been published. In order to explore the research hotspots and trends in this field, a bibliometric and visual analysis was performed for the first time.Methods: The literature records related to oncology robotic surgery were obtained from the Web of Science Core Collection database and imported into the software VOSviewer 1.6.18, CiteSpace 6.1.R3, and the Bibliometric Online Analysis Platform for analysis.
    Results: A total of 6,964 publications, including 5,635 articles and 1,329 reviews, were included in this study. Over the past 20 years, annual publications and citations have experienced rapid growth, particularly in the last two years. The United States was the country with the most publications, while Yonsei University in South Korea was the most productive institution. The Journal of Robotic Surgery and the Journal of Urology were the journals with the most publications and citations, respectively. Mottrie A from Belgium and Ficarra V from Italy were the authors with the highest number of publications and citations, respectively. The keywords "robotic surgical procedure", "laparoscopic surgery", "prostate cancer", "colorectal cancer", "gastric cancer", "resection", "complications classification", "open surgery", "transoral robotic surgery", "pathological outcomes", and "robot-assisted surgery" reflect the research hotspots and trends of oncology robotic surgery.
    Conclusion: The therapeutic advantages of robotic surgery in oncology are not yet prominent, and further randomized controlled trials with multicenter and large samples are needed to evaluate the advantages of robotic surgery compared with laparoscopic surgery and open surgery in the treatment of tumors from multiple outcome indicators.
    Keywords:  CiteSpace; VOSviewer; bibliometric; oncology; robotic surgery; visual analysis
    DOI:  https://doi.org/10.3389/fonc.2022.1055118
  14. Front Surg. 2022 ;9 1021534
    Top 100 most-cited articles on hemorrhoids: A bibliometric analysis and visualized study.
    Zhaochu Wang, Xuxiong Wu, Yang Li, Juan Huang, Rong Shi, Jing Wang.
      Background: Hemorrhoids have a significant incidence in people and are becoming a common public health problem. This study provides a bibliometric and visualized analysis of the most influential literature in the field. The aim is to reveal trends in the field of hemorrhoids and to provide a reference for researchers.Methods: The 100 most frequently cited studies in the field of hemorrhoids were collected from the Web of Science(WOS), and were analyzed in terms of the annual publication, types of literature, countries, institutions, authors, journals, and keywords. During the study, we used a combination of VosViewer, Carrot2, Microsoft Excel, and Tableau tools to better present the visual information.
    Results: A total of 4,481 articles were retrieved, of which 3,592 were of the Article and Review types, among which we selected the 100 most frequently cited. A large amount of highly cited literature on hemorrhoid surgery emerged from 1990 to 2010, and the interest of researchers in hemorrhoid surgery seems to have waned after 2010. The sources of highly cited literature in the field of hemorrhoids are predominantly Western, with the United States. and the United Kingdom accounting for almost half of the publications worldwide. However, countries with higher prevalence populations do not have significant research on hemorrhoids. St. Mark's Hospital has published the largest number of influential articles in the field of hemorrhoid disease. Kamm MA and Phillips RKS are the most authoritative authors in the field. Diseases of the Colon & Rectum and the British Journal of Surgery are the most influential journals in this field. The highly cited literature covers a wide range of disciplines, with Thomson's classic "The nature of hemorrhoids" receiving the most attention among the studies focusing on hemorrhoids. Keyword and clustering analysis revealed that The most famous focus in the field of hemorrhoid research is the evolution of stapled hemorrhoidectomy (SH) and Milligan-morgan hemorrhoidectomy (MMH).
    Conclusions: This study is the first to explore developments in the field of hemorrhoids, and it helps surgeons quickly understand global trends in the field of hemorrhoids. In recent years, the development of hemorrhoids seems to have hit a bottleneck, with scholarly interest in the field of waning, especially in surgery Procedures. The theory of inferior anal cushion migration has proven to be the most influential theory in the field, but after studies based on SH and MMH, more high-quality evidence is needed to continue advancing the field of hemorrhoids. The results of this study are intended to add to the attention and interest of scholars in this area and provide a reference for further research.
    Keywords:  Milligan-morgan hemorrhoidectomy; bibliometric; hemorrhoids; stapled hemorrhoidectomy; visualized study
    DOI:  https://doi.org/10.3389/fsurg.2022.1021534
  15. Indian J Palliat Care. 2022 Oct-Dec;28(4):28(4): 338-353
    Bibliometric Analysis of Indian Journal of Palliative Care from 1995 to 2022 using the VOSviewer and Bibliometrix Software.
    Rajashree Srivastava, Shikha Srivastava.
      Introduction: The Indian Journal of Palliative Care (IJPC) is an open-source, interdisciplinary and peer-reviewed journal started in 1994 that publishes high-quality articles in the field of palliative care in India. The purpose of this study is to analyse the bibliometric data of its publications using bibliometric analysis to understand the key bibliometric factors affecting the journal and its contribution to the field of palliative care research.Material and Methods: A software-assisted bibliometric analysis of the IJPC was conducted. The dimensions database was used to mine the bibliometric data of the journal from 1995 to 2022. A total of 1046 records were analysed using the VOSviewer and Biblioshiny by Bibliometrix software.
    Results: The analysis represented a vivid and graphically elaborate picture of the journal. It gives insight into the most productive and influential authors, countries, affiliations, sources and documents along with a picture of the network among them.
    Conclusion: This study highlights a gradual upward trend in the annual production of the journal. A strong connection of the IJPC could be seen with leading journals publishing in the field of palliative care globally.
    Keywords:  Bibliometrics; Indian journal of palliative care; Single journal study; VOSviewer; Visual mapping
    DOI:  https://doi.org/10.25259/IJPC_30_2022
  16. Heliyon. 2022 Nov;8(11): e11849
    Psychological capital in university students: analysis of scientific activity in the scopus database.
    Jesús Manuel Guerrero-Alcedo, Lorena C Espina-Romero, Jessica Paola Palacios Garay, Freddy Roberpierre Jaimes Álvarez.
      Lately there has been an increase in the number of publications on psychological capital, especially in the specialty of organizational psychology, and not so much in the field of educational psychology. This study aims to analyze the main bibliometric indicators of production, collaboration and impact of scientific literature related to psychological capital in university students. We searched the Scopus database for documents using the comprehensive search strategy until June 27, 2021. Data were collected regarding title, keywords, authors, co-authors, citations received, details of the most productive journals, year of publication, countries, and institutions. From 2009 to 2021, 82 documents were published, mainly from countries such as China, Australia, the United Kingdom, the United States and Spain; the most productive journal was the so-called Revista Argentina de Clínica Psicológica while Curtin University was the most influential institution in the subject of study. The author's co-occurrence network analysis, trend topics, and keyword analysis highlighted themes involving psychological capital with educational and health variables in college students. The findings can help both academics and professionals to obtain an overview of advances in the subject and thus identify important gaps in the literature and propose promising new lines of research.
    Keywords:  Bibliometric review; Psycap; Psychological capital; Students; University
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e11849
  17. Biomed Res Int. 2022 ;2022 8564649
    Pandemic Critical Care Research during the COVID-19 (2020-2022): A Bibliometric Analysis Using VOSviewer.
    Mohammed Ageel.
      This paper has reviewed the global research on the pandemic critical care research during the COVID-19 from 2020 to 2022. To this end, a bibliometric and cluster analysis by full counting has been carried out using VOSviewer software and bibliographic data extracted from the Scopus database. The research found and studied 2778 documents. The types of research documents were limited to an article (81.46%), a letter (9.43%), an editorial (3.92%), a note (3.92%), a conference paper (0.90), and a short survey (0.04%). The results show an incessant increase in the number of research documents published and citations received during the COVID-19 pandemic. The U.S., U.K., Italy, and France have been shown to be the most productive countries, and there is a predominance of European institutions supporting and fostering research on pandemic critical care. Cecconi, M. (Italy) and Shankar-Hari, M. (U.K.) produced the highest number of research documents. Mapping of citation, co-citation, co-authorship, and keyword cooccurrence highlighted the hotspot, knowledge structure, and important themes. Citation dynamics for the top-cited research documents revealed static discourse. By reviewing the evolutionary trends of pandemic critical care research investigated factors, such as the influential works, main research topics, and the research frontiers, this paper reveals the scientific literature production's main research objectives and directions that could be addressed and explored in future studies. This paper reveals the scientific literature production's main research objectives and directions that could be addressed and explored in future studies after reviewing the evolutionary trends of pandemic critical care research during the COVID-19 and the investigated factors, such as influential works, main research topics, and research frontiers.
    DOI:  https://doi.org/10.1155/2022/8564649
  18. Front Oncol. 2022 ;12 999203
    The global research of bladder cancer immunotherapy from 2012 to 2021: A bibliometric analysis.
    Qiuqiu Qiu, Can Deng, Hanqiang Li, Junhui Qiu, Zefeng Shen, Yongquan Ding.
      Intravesical instillation of Bacillus Calmette-Guérin has been used as an immunotherapy to treat superficial bladder cancer for almost half a century. In recent years, the approval of several monoclonal antibody treatments has transformed the treatment landscape for patients with muscle-invasive or metastatic uroepithelial carcinoma. The purpose of this study was to conduct a thorough review of immunotherapy in bladder cancer through a bibliometric approach. Publications related to bladder cancer immunotherapy were obtained from the Web of Science Core Collection on July 1st, 2022. We conducted a bibliometric analysis of literature information using CiteSpace IV, VOSviewer, and Scimago Graphica, including co-authorship or co-citation of authors, countries/regions, journals, references, and keyword co-occurrence. There was a total of 2,352 papers included, with the most contributions coming from the United States, China, and Italy. The United States had the highest H-index value and was the leading country in this field. Meanwhile, the number of publications in China was steadily growing. The top three productive researchers were Kamat AM, Necchi A, and Shariat SF, with Powles T as the top co-cited author. Most papers were published by the University of Texas System. The majority of papers in this field were published in Urologic Oncology Seminars and Original Investigations and European Urology was the most influential journal with the highest H-index. The tumor microenvironment and complete molecular characterization may still be the frontier in this research area, allowing us to obtain a better understanding of the pathogenesis and clinical prognosis of bladder cancer. More research are conducted to identify clinically meaningful biomarkers that may provide opportunities for the personalization of bladder cancer therapy. This study provides clinicians and researchers with an overview and helpful guidance on how to choose the research direction and management of bladder cancer immunotherapy.
    Keywords:  bibliometrics; bladder cancer; immune checkpoint inhibitor; immunotherapy; metastatic urothelial carcinoma
    DOI:  https://doi.org/10.3389/fonc.2022.999203
  19. J Med Internet Res. 2022 Nov 30. 24(11): e42185
    Artificial Intelligence in Intensive Care Medicine: Bibliometric Analysis.
    Ri Tang, Shuyi Zhang, Chenling Ding, Mingli Zhu, Yuan Gao.
      BACKGROUND: Interest in critical care-related artificial intelligence (AI) research is growing rapidly. However, the literature is still lacking in comprehensive bibliometric studies that measure and analyze scientific publications globally.OBJECTIVE: The objective of this study was to assess the global research trends in AI in intensive care medicine based on publication outputs, citations, coauthorships between nations, and co-occurrences of author keywords.
    METHODS: A total of 3619 documents published until March 2022 were retrieved from the Scopus database. After selecting the document type as articles, the titles and abstracts were checked for eligibility. In the final bibliometric study using VOSviewer, 1198 papers were included. The growth rate of publications, preferred journals, leading research countries, international collaborations, and top institutions were computed.
    RESULTS: The number of publications increased steeply between 2018 and 2022, accounting for 72.53% (869/1198) of all the included papers. The United States and China contributed to approximately 55.17% (661/1198) of the total publications. Of the 15 most productive institutions, 9 were among the top 100 universities worldwide. Detecting clinical deterioration, monitoring, predicting disease progression, mortality, prognosis, and classifying disease phenotypes or subtypes were some of the research hot spots for AI in patients who are critically ill. Neural networks, decision support systems, machine learning, and deep learning were all commonly used AI technologies.
    CONCLUSIONS: This study highlights popular areas in AI research aimed at improving health care in intensive care units, offers a comprehensive look at the research trend in AI application in the intensive care unit, and provides an insight into potential collaboration and prospects for future research. The 30 articles that received the most citations were listed in detail. For AI-based clinical research to be sufficiently convincing for routine critical care practice, collaborative research efforts are needed to increase the maturity and robustness of AI-driven models.
    Keywords:  artificial intelligence; bibliometric analysis; intensive care medicine; machine learning; sepsis
    DOI:  https://doi.org/10.2196/42185
  20. Front Pharmacol. 2022 ;13 1004525
    Global trends and Frontier topics about vascular smooth muscle cells phenotype switch: A bibliometric analysis from 1999 to 2021.
    Ying Han, Langchao Yan, Lu Xia, Shifu Li, Qian Zhang, Chen Jin.
      Objective: Vascular smooth muscle cell phenotype switch (VSMCPS) plays a significant role in vascular remodeling. This study aimed to conduct a bibliometric analysis and visualize the knowledge map of research on VSMCPS. Methods: We retrieved publications focusing on VSMCPS from the Web of Science Core Collection database (SCI-EXPANDED) from 1999 to 2021. Using bibliometric tools, VOSviewer and CiteSpace, we identified the most productive researchers, journals, institutions, and countries. At the same time, the trends, hot topics, and knowledge networks were analyzed and visualized. Results: A total of 2213 publications were included in this analysis. The number of annual publications in the VSMCPS field exhibited an upward trend and could be roughly divided into three phases. Until 2006, the most prolific authors were from the United States. As of 2008, the number of articles published in China increased dramatically to reach 126 papers in 2020. As of 2014, China was the most productive country in this field. The United States ranked first in the number of highly-influential authors, institutions, and literature from 1999 to 2022. Owens GK, Hata, Akiko, and Wen, jin-kun were the most prolific authors. Arteriosclerosis Thrombosis and Vascular Biology, Circulation Research, and Cardiovascular Research were the top-ranked journals in this field. "Vascular remodeling," "atherosclerosis," "neointima," "hypertension", and "inflammation" were the main researched topics. New diseases, new mechanisms, and new phenotype (e.g., micro RNA, macrophage-like-cell, hypoxia, autophagy, long noncoding RNA, oxidative stress, endoplasmic reticulum stress, senescence, aging, abdominal aortic aneurysm, and aortic dissection) represent the trending topics in recent years. Conclusion: This study systematically analyzed and visualized the knowledge map of VSMCPS over the past 2 decades. Our findings provide a comprehensive overview for scholars who want to understand current trends and new research frontiers in this area.
    Keywords:  VOSviewer; bibliometric; citespace; phenotype switching; vascular smooth muscle cells
    DOI:  https://doi.org/10.3389/fphar.2022.1004525
  21. Indian J Psychiatry. 2022 Sep-Oct;64(5):64(5): 497-504
    Suicide and suicidal ideation in the times of the Covid-19 pandemic: A scientometric analysis.
    Rajat Jagdish Palod, Mahika Milind Joshi, Rupali Kumar, Virendra Siddharam Ligade.
      Objectives: The article aims to explore the studies performed on suicide because of coronavirus disease 19 through a bibliometric analysis. A quantitative analysis of the topic furnishes data on the publication pattern, influential research journals, highly cited articles, productive countries and organizations, the authorship pattern, and the collaborative pattern between authors.Methods: Data regarding the type of documents, most cited articles, influential research journals, contributions per country, and so on were extracted for the study from the Scopus database. Data analysis and visualization were performed through R-Studio and the VOSviewer application.
    Results: A bibliometric analysis encompassing scientific contributions based on suicide or suicide-related ideation because of the coronavirus pandemic showed a total of 494 documents published in 230 journals/books. The articles published by proficient authors in reputed journals highlighted the key areas of research in the field. USA dominated the list of scientific production of countries contributing to 340 documents.
    Conclusion: The results provided by this analysis could act as a steppingstone for experts to design a roadmap for mental health research during the pandemic. Studies can be designed to gather information on mental health conditions across specific age groups. Research collaborations that facilitate the publication of pooled protocols and data are encouraged.
    Keywords:  Anxiety; bibliometric analysis; coronavirus; depression; mental health
    DOI:  https://doi.org/10.4103/indianjpsychiatry.indianjpsychiatry_382_21
  22. Undersea Hyperb Med. 2022 Fourth Quarter;49(4):49(4): 519-532
    Hyperbaric oxygen therapy research: an analysis of the 100 most-cited publications from 2011 to 2020.
    Hsin-Tzu Yeh, Ching-Hsing Lee.
      Objective: Hyperbaric oxygen (HBO2) is used in several clinical and research fields. This study aimed to analyze the 100 most-cited hyperbaric-related publications of the past 10 years to understand the trends in HBO2 research.Methods: This was a literature review. All publication and citation data were retrieved from the Scopus database. Publications with "hyperbaric oxygen," "hyperbaric oxygenation," "HBO," and "HBOT" in the title, abstract, or keywords published between January 01, 2011, and December 31, 2020, were enrolled. The 100 most-cited HBO2-focused publications were identified, and their publication title, authors' nationality, publication journal, year, type (original or review), and application field were recorded and analyzed using descriptive statistics. Linear regression was used to evaluate the trends in publication numbers.
    Results: A total of 6,517 publications were enrolled. The annual rate of increase was 4.56 per year (p-value = 0.13, 95% CI: -1.62 to 10.74). The total, average, median and mode of citations were 67,726, 10.4, 4, and 0, respectively. The 100 most-cited HBO2-focused publications accounted for 1.5% (100/6,517) of all publications and 8.1% (5509/67,726) of the total number of times cited. The most-cited publications originated from 17 countries and were published in 65 journals, led by the Cochrane Database of Systematic Reviews.
    Conclusions: The annual number of HBO2 publications was stationary. The citation numbers showed a skewed distribution. The United States was the leading country in HBO2 research. Of 26 application fields, traumatic brain injury, stroke, and diabetic foot were the leading three fields.
    Keywords:   citation ; hyperbaric oxygen ; hyperbaric oxygen treatment ; publication
    DOI:  https://doi.org/10.22462/07.08.2022.11
  23. Front Psychol. 2022 ;13 1016601
    Demoralization: Where it stands-and where we can take it: A bibliometric analysis.
    Qingyong Zheng, Lu Xiong, Huijun Li, Ming Liu, Jianguo Xu, Xiaofeng Luo.
      Objectives: The purpose is to analyze existing studies related to the field of demoralization through bibliometrics.Methodology: Relevant literature on demoralization was searched from PubMed, Web of Science, the Cochrane Library, and CINAHL Complete. Bibliometric analysis was performed using GraphPad Prisma 8.2.1, VOSviewer 1.6.18 and R software. Research publication trends, author-country collaboration, research hotspots and future trends were explored by generating network relationship maps.
    Results: A total of 1,035 publications related to the field of demoralization were identified. The earliest relevant studies have been published since 1974, and the studies have grown faster since 2000. Psyche-oncology and Psychother Psychosom had the highest number of publications (n = 25). The United States, Italy and Australia have made outstanding contributions to the field and there was an active collaboration among leading scholars. Major research hotspots include the multiple ways of assessing demoralization, the specificity of various demographics and psychological disorders in different disease contexts, and the association and distinction of diverse clinical psychological abnormalities. The impact of COVID-19 on demoralization and subsequent interventions and psychological care may become a future research direction.
    Conclusion: There has been a significant increase in research in the field of demoralization after 2000. The United States provided the most publications. There is overall active collaboration between authors, countries, and institutions. In future research, more attention will be paid to the effects of COVID-19 on demoralization and intervention care for this psychology.
    Keywords:  COVID-19; bibliometrics; data visualization; demoralization; development history; psychological distress
    DOI:  https://doi.org/10.3389/fpsyg.2022.1016601
  24. Environ Sci Pollut Res Int. 2022 Dec 02.
    A bibliometric and visual analysis of contaminant transport modeling in the groundwater system: current trends, hotspots, and future directions.
    Abhay Guleria, Sumedha Chakma.
      Contaminant transport modeling (CTM) in the groundwater represents the complex bio-geo-chemical processes in the subsurface system and plays a vital role in designing remediation strategies for contaminated sites. Hence, this study evaluated 1955 articles on CTM-based studies published from 2010 to 2022 by utilizing the Scopus® database to provide a quantitative analysis of current trends and future directions. A systematic approach comprised of a bibliometric survey and visualization of various networks was conducted with the VOSviewer and Biblioshiny software for quantitative analysis of progress of CTM research field over the past decade. The hotspots and evolution of themes of CTM were found using Sankey diagrams, and thematic maps. It was observed that articles were published at an exponential rate over past 5 years. The analysis of Scopus® database revealed that the average citations per article and the average citations per year per article were 14.7 and 2.225. In the past decade, USA published 489 articles and emerged as the leading country based on mutual collaborations and cooperation with other top 9 most productive countries. Flinders University was ranked in the first position based on the number of articles, followed by Pacific Northwest National Laboratory. The findings obtained from this study can help researchers identify exploitation and core areas, to understand better the direction of research of mathematical model development, and to determine hotspots of CTM research field.
    Keywords:  Bibliometric analysis; Biblioshiny; Contaminant transport modeling; Groundwater; Research hotspots; VOSviewer
    DOI:  https://doi.org/10.1007/s11356-022-24370-1
  25. Front Med (Lausanne). 2022 ;9 975376
    Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021.
    Menghan Mao, Yanyu Zhou, Yingfu Jiao, Suqing Yin, Chiwai Cheung, Weifeng Yu, Po Gao, Liqun Yang.
      Background and aims: The gut microbiota is involved in the regulation of pain, which is proved by plenty of evidence. Although a substantial quantity of research on the link between the gut microbiota and pain has emerged, no study has focused on the bibliometric analysis of this topic. We aim to present a bibliometric review of publications over the past 20 years and predict research hot spots.Methods: Relevant publications between 2002 and 2021 were extracted from the Science Citation Index-Expanded (SCI-EXPANDED) of the Web of Science Core Collection (WoSCC) database on April 22, 2022. CiteSpace (version 5.8 R3c), VOSviewer, the Online Analysis Platform of Literature Metrology, and the R package bibliometrix were used to analyze and visualize.
    Results: A total of 233 articles have been published between 2002 and 2021. The number of publication outputs increased rapidly since 2016. The collaboration network revealed that the USA, Baylor College of Medicine, and Vassilia Theodorou were the most influential country, institute, and scholar, respectively. Alimentary pharmacology and therapeutics and Gut were the most co-cited journal and Neurogastroenterology and Motility was the most productive journal. Visceral sensitivity, fibromyalgia, gastrointestinal, chronic pain, stress, gut microbiome, LGG, brain-gut axis, SLAB51, and sequencing were the top 10 clusters in co-occurrence cluster analysis. Keyword burst detection indicated that the brain-gut axis and short-chain fatty acid were the current research hot spots.
    Conclusion: Research on the links between the gut microbiota and pain has increased rapidly since 2016. The current research focused on the brain-gut axis and short-chain fatty acid. Accordingly, the SCFAs-mediated mechanism of pain regulation will be a research direction of great importance on the links between the gut microbiota and pain. This study provided instructive assistance to direct future research efforts on the links between the gut microbiota and pain.
    Keywords:  CiteSpace; bibliometric analysis; gut microbiota; hot spots; pain
    DOI:  https://doi.org/10.3389/fmed.2022.975376
  26. Front Pharmacol. 2022 ;13 1042594
    A bibliometric analysis of the recent advances in diazepam from 2012 to 2021.
    Ming Zhang, Lin Kou, Yaya Qin, Junwen Chen, Dazhang Bai, Li Zhao, Hongyu Lin, Guohui Jiang.
      Background: Diazepam is a classic benzodiazepine drug that has been widely used for disorders such as anxiety, sleep disorders, and epilepsy, over the past 59 years. The study of diazepam has always been an important research topic. However, there are few bibliometric analyses or systematic studies in this field. This study undertook bibliometric and visual analysis to ascertain the current status of diazepam research, and to identify research hotspots and trends in the past 10 years, to better understand future developments in basic and clinical research. Methods: Articles and reviews of diazepam were retrieved from the Web of Science core collection. Using CiteSpace, VOSviewer, and Scimago Graphica software, countries, institutions, authors, journals, references, and keywords in the field were visually analyzed. Results: A total of 3,870 publications were included. Diazepam-related literature had high volumes of publications and citations. The majority of publications were from the USA and China. The highest number of publications and co-citations, among the authors, was by James M Cook. Epilepsia and the Latin American Journal of Pharmacy were the journals with the most publications on diazepam and Epilepsia was the most frequently cited journal. Through a comprehensive analysis of keywords and references, we found that current research on diazepam has focused on its mechanism of action, application in disease, pharmacokinetics, risk, assessment, and management of use, status epilepticus, gamma-aminobutyric acid receptors (GABAR), intranasal formulation, gephyrin, and that ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) is the current research hotspot. Conclusion: Research on diazepam is flourishing. We identified research hotspots and trends in diazepam research using bibliometric and visual analytic methods. The clinical applications, mechanisms of action, pharmacokinetics, and assessment and management of the use of diazepam are the focus of current research and the development trend of future research.
    Keywords:  CiteSpace; VOSviewer; Web of Science; bibliometrics; diazepam; visual analysis
    DOI:  https://doi.org/10.3389/fphar.2022.1042594
  27. Front Oncol. 2022 ;12 1055366
    Research on application of tumor treating fields in glioblastoma: A bibliometric and visual analysis.
    Xue Du, Chunbao Chen, Yu Xiao, Yu Cui, Lu Yang, Xiaochun Li, Xueping Liu, Ruisi Wang, Bangxian Tan.
      Background: Glioblastoma, one of the common tumors of the central nervous system (CNS), is prone to recurrence even after standard treatment protocols. As an innovative physiotherapy method emerging in recent years, the tumor treating fields (TTFields) technique has been approved for the treatment of glioblastoma due to its non-invasive and portable features. The purpose of this study is to visualize and analyze the scientific results and research trends in TTFields therapy for glioblastoma.Methods: Publications related to TTFields therapy for glioblastoma were searched in the Web of Science Core Collection (WoSCC) database in September 2022. A bibliometric and visual analysis of publications in this field was performed mainly using CiteSpace and R software for country/region, author, journal, reference and keyword.
    Results: A total of 618 publications in this field were retrieved, and 248 were finally obtained according to the search criteria, including 159 articles (64.11%) and 89 reviews (37.89%). The cumulative number of publications increased year by year, with an average growth rate (AGR) of 28.50%. The test results of Pearson correlation coefficient showed a high positive correlation between publications and citations (r=0.937, p<0.001). The USA had the largest number of publications (123, 49.60%), followed by Germany (32, 12.90%) and China (30, 12.10%). As for the country/region collaborations, the USA cooperated most closely with other countries/regions, followed by Germany and China. The degree of collaboration (DC) between countries/regions was 25.81%. The institutions with the largest number of publications were Tel Aviv Univ (10), Harvard Med Sch (10) and Novocure Ltd (10). Moreover, Wong E (18) possessed the greatest number of publications, followed by Weinberg U (11) and Kirson E (10). The DC between authors was 97.58%. STUPP R (236) was the most cited author followed by KIRSON ED (164) and GILADI M (104). JOURNAL OF NEURO-ONCOLOGY (22) was the journal with the largest number of published publications (75), followed by FRONTIERS IN ONCOLOGY (15) and CANCERS (13). The top 10 keywords that occurred frequently included glioblastoma (156), tumor treating field (152), temozolomide (134), randomized phase III (48), brain (46), survivor (46), cancer (44), trial (42), alternating electric field (42) and radiotherapy (36). Furthermore, cluster analysis was performed on the basis of keyword co-occurrence, and finally 15 clusters were formed to determine the current research status and future development trend of TTFields therapy for glioblastoma.
    Conclusion: TTFields has been increasingly known as the fourth novel physical anti-tumor therapy in addition to surgery, radiotherapy and anti-tumor drugs. Cooperation and communication between countries/regions need to be enhanced in future research. Several studies have demonstrated the therapeutic potential of TTFields in glioma, and its application alone or in combination with other treatments has become a current research hotspot.
    Keywords:  bibliometrics; citespace; glioblastoma; tumour treating fields; visual analysis
    DOI:  https://doi.org/10.3389/fonc.2022.1055366
  28. Front Cardiovasc Med. 2022 ;9 1021346
    Bibliometric and visual analysis of coronary microvascular dysfunction.
    Xiaoxiao Lin, Guomin Wu, Beibei Gao, Shuai Wang, Jinyu Huang.
      Background: Coronary microvascular dysfunction (CMD) may play an important role in various cardiovascular diseases, including HFpEF and both obstructive and non-obstructive coronary artery disease (CAD). To date, there has been no bibliometric analysis to summarize this field. Here, we aim to conduct a bibliometric analysis of CMD to determine the current status and frontiers in this field.Materials and methods: Publications about CMD were taken from the Web of Science Core Collection database (WOSCC). WOSCC's literature analysis wire, the VOSviewer 1.6.16, and CiteSpace 5.1.3 were used to conduct the analysis.
    Results: A total of 785 publications containing 206 reviews and 579 articles are included in the sample. The leading authors are Iacopo Olivotto, Paolo G. Camici, and Carl J. Pepine. The most productive institutions are the University of Florence, Cedars Sinai Medical Center, and Harvard University. The most productive countries are the USA, Italy, and England. There are a total of 237 journals that contribute to this field, and the leading journals in our study were the International Journal of Cardiology, the European Heart Journal and the JACC. From 2012 to 2021, the top three most-cited articles focused on the association between HFpEF and CMD. The important keywords are heart failure, hypertrophic cardiomyopathy, chest pain, women, coronary flow reserve (CFR), endothelial dysfunction and prognostic value. "Positron emission tomography" shows the strongest burst strength, followed by "blow flow" and "artery." The keywords that started to burst from 2015 are particularly emphasized, including "heart failure," "coronary flow reserve," and "management."
    Conclusion: Studies about CMD are relatively limited, and the largest contribution comes from the USA, Italy and England. More studies are needed, and publications from other countries should be enhanced. The main research hotspots in the CMD field include CMD in patients with HFpEF, sex differences, the new methods of diagnosis for CMD, and the effective treatment of CMD. Attention should be given to CMD in patients with HFpEF, and untangling the association between CMD and HFpEF could be helpful in the development of physiology-stratified treatment for patients with CMD and HFpEF.
    Keywords:  HFpEF; bibliometric analysis; coronary microvascular dysfunction (CMD); treatment; visual maps
    DOI:  https://doi.org/10.3389/fcvm.2022.1021346
  29. J Prosthet Dent. 2022 Nov 24. pii: S0022-3913(22)00653-9. [Epub ahead of print]
    Mapping the trends and impact of research collaboration between countries in oral implantology publications: A bibliometric analysis from 1999 to 2019.
    Caroline Dini, Marta Maria Alves Pereira, João Gabriel Silva Souza, Erica Dorigatti de Avila, Valentim Adelino R Barão.
      STATEMENT OF PROBLEM: Scientific collaboration provides a suitable strategy for enhancing the exchange of knowledge and technological development. However, the impact of collaboration in oral implantology research between countries and how it has been influenced by the income status of the country has not been previously evaluated.PURPOSE: The purpose of this bibliometric analysis was to evaluate how collaboration between countries affected oral implant publications and whether patterns of collaboration differ depending on the country's income.
    MATERIAL AND METHODS: Articles were retrieved from 7 well-established journals whose scope included oral implantology at 5 time points (1999, 2004, 2009, 2014, and 2019). Data were extracted, and descriptive, bivariate, and multivariate logistic regression analyses were performed (α=.05).
    RESULTS: A total of 1944 articles were included; of which, 27.5% presented collaboration between countries. In 2009, 2014, and 2019, collaboration between countries was more likely to occur than at previous time points (P≤.005). Corresponding authors with a higher h-index (P<.05) and authors from Europe and North America (P<.001) were more likely to establish international connections. The possibility of collaboration between countries was higher for animal studies (P<.001) and for articles published by Clinical Oral Implants Research (P=.026). Collaborations between high-income and upper-middle- or lower-middle-income countries were more likely to happen in 2014 and 2019 (P<.05), as well as when the number of authors was higher (P=.015), compared with collaboration between high-income countries. With regard to the continent, European articles were less likely to have collaborations with upper-middle- or lower-middle-income countries (P<.001).
    CONCLUSIONS: The findings revealed that some parameters related to the study, authors, countries, and journals were statistically associated with the presence of collaboration between countries. However, the bibliometric parameters showed different trends when countries of different incomes established collaboration.
    DOI:  https://doi.org/10.1016/j.prosdent.2022.10.009
  30. Front Hum Neurosci. 2022 ;16 1044917
    Association between electroconvulsive therapy and depressive disorder from 2012 to 2021: Bibliometric analysis and global trends.
    Haipeng Cai, Ruonan Du, Kebing Yang, Wei Li, Zhiren Wang.
      Background: Depressive disorder is a chronic mental illness that is vulnerable to relapse, imposes a huge economic burden on society and patients, and is a major global public health problem. Depressive disorders are characterized by depressed mood, decreased energy and interest, and suicidal ideation and behavior in severe cases. They can be treated through pharmacotherapy and psychotherapy or physical treatments such as electroconvulsive therapy (ECT). In patients with suicidal ideation, behavior, or refractory depressive disorder ECT has a faster onset of action and better efficacy than pharmacotherapy. This study used bibliometric and visual analyses to map the current state of global research on ECT for depressive disorder and to predict future research trends in this area.Materials and methods: A literature search was performed for studies on ECT and depressive disorder in the Web of Science Core Collection (WoSCC) database. All studies considered for this paper were published between 2012 and 2021. Bibliometric and co-occurrence analyses were performed using the CiteSpace software.
    Results: In total, 2,184 publications were retrieved. The number of publications on ECT and depressive disorder have been increasing since 2012, with China being a emerging hub with a growing influence in the field. Zafiris J. Daskalakis is the top author in terms of number of publications, and The Journal of ECT is not only the most published journal but also the most co-cited journal in the field. Co-occurrence analysis showed that electroconvulsive therapy, treatment-resistant depression, bipolar disorder, hippocampus, efficacy, and electrode placement are current research hotspots. Molecular biomarkers, neuroimaging predictors, and late-life depression will become research hotspots in the future.
    Conclusion: Our analysis made it possible to observe an important growth of the field since 2012, to identify key scientific actors in this growth and to predict hot topics for future research.
    Keywords:  CiteSpace; bibliometrics analysis; depressive disorder; electroconvulsive therapy; global trends
    DOI:  https://doi.org/10.3389/fnhum.2022.1044917
  31. Front Psychiatry. 2022 ;13 1017506
    Research trends in social media addiction and problematic social media use: A bibliometric analysis.
    Alfonso Pellegrino, Alessandro Stasi, Veera Bhatiasevi.
      Despite their increasing ubiquity in people's lives and incredible advantages in instantly interacting with others, social media's impact on subjective well-being is a source of concern worldwide and calls for up-to-date investigations of the role social media plays in mental health. Much research has discovered how habitual social media use may lead to addiction and negatively affect adolescents' school performance, social behavior, and interpersonal relationships. The present study was conducted to review the extant literature in the domain of social media and analyze global research productivity during 2013-2022. Bibliometric analysis was conducted on 501 articles that were extracted from the Scopus database using the keywords social media addiction and problematic social media use. The data were then uploaded to VOSviewer software to analyze citations, co-citations, and keyword co-occurrences. Volume, growth trajectory, geographic distribution of the literature, influential authors, intellectual structure of the literature, and the most prolific publishing sources were analyzed. The bibliometric analysis presented in this paper shows that the US, the UK, and Turkey accounted for 47% of the publications in this field. Most of the studies used quantitative methods in analyzing data and therefore aimed at testing relationships between variables. In addition, the findings in this study show that most analysis were cross-sectional. Studies were performed on undergraduate students between the ages of 19-25 on the use of two social media platforms: Facebook and Instagram. Limitations as well as research directions for future studies are also discussed.
    Keywords:  bibliometric analysis; problematic social media use; research trends; social media; social media addiction
    DOI:  https://doi.org/10.3389/fpsyt.2022.1017506
  32. Front Neurol. 2022 ;13 1029613
    Worldwide productivity and research trends of publications concerning stent application in acutely ruptured intracranial aneurysms: A bibliometric study.
    Rundong Chen, Yanpeng Wei, Guanghao Zhang, Renkun Zhang, Xiaoxi Zhang, Dongwei Dai, Qiang Li, Rui Zhao, Yi Xu, Qinghai Huang, Pengfei Yang, Qiao Zuo, Jianmin Liu.
      Background: Stenting is a common clinical practice to treat acutely ruptured intracranial aneurysm (RIA). Although multiple studies have demonstrated its long-term safety and effectiveness, there is currently a lack of bibliometric analysis on stent application in acutely RIA. This study sought to summarize the current status of research in this field and lay a foundation for further study.Materials and methods: Related publications were searched in the Web of Science Core Collection (WoSCC) database. Data analysis and visualization were performed by R and CiteSpace software.
    Results: A total of 275 publications published in English from 1997 to 2022 were included in this study. The growth of publications slowed down. The reference co-citation network identified 13 clusters with a significant network (Q = 0.7692) and convincing clustering (S = 0.9082). The research focus was acutely RIA and the application of stents during interventional procedures. The main trends of research were: (1) development of materials, and (2) safety of stent application in acutely RIA. The United States contributed the most articles, and Jianmin Liu was the most prolific author. Mayo Clinic was the leading institution in this field. Most articles were published in Interventional Neuroradiology.
    Conclusions: This study analyzed the research trends, hotspots and frontiers of stent application in acutely RIA. It is our hope that the results obtained could provide useful information to researchers to get a clearer picture about their future research directions in this field.
    Keywords:  Citespace; bibliometric; cluster analysis; ruptured intracranial aneurysms; stent application; stent-assisted coiling
    DOI:  https://doi.org/10.3389/fneur.2022.1029613
  33. Orthop J Sports Med. 2022 Nov;10(11): 23259671221137051
    A Scientometric Analysis of Studies on Patellar Dislocation.
    Hong Wang, Zhi Yi, Hongwei Zhan, Yuanjun Teng, Shifeng Zhang, Meng Wu, Bin Geng, Yayi Xia.
      Background: Patellar dislocation is attracting considerable research interest.Purpose: To assess studies on patellar dislocation using a scientometric method to better understand the current status of research and explore future study directions.
    Study Design: Scoping review.
    Methods: The Web of Science Core Collection database was selected to retrieve publications on patellar dislocation. Articles and reviews written in English with patellar dislocation as the main topic were included. Conference abstracts, notes, letters, expert opinions, and animal studies were excluded. A total of 4632 articles were identified in our initial search. In addition, Excel 2019, CiteSpace 6.1.R1, and VOSviewer 1.6.9 were used to analyze the h-index, the most highly cited publication, publication essentials, and research themes.
    Results: A total of 1485 articles were included in our analysis, with 36,608 citations and an h-index of 93. Overall, 1494 institutions and 195 journals were identified from these studies. The United States (n = 531) was the most productive country. The institution and journal with the largest number of articles were the Hospital for Special Surgery (n = 59) and Knee Surgery, Sports Traumatology, Arthroscopy (n = 212), respectively. The article "Scoring of Patellofemoral Disorders" by Kujala et al in 1993 was the most highly cited reference. The most commonly found terms used were patellar dislocation, patellar instability, medial patellofemoral ligament, knee, recurrent patellar dislocation, and soft tissue restraints. Four topics were identified after clustering analysis of key terms: risk factors, medial patellofemoral ligament reconstruction, patellar dislocation in skeletally immature patients, and lateral retinacular release.
    Conclusion: This scientometric review of articles on patellar dislocation summarized the current status of research (countries, institutions, and authors) and identified potential research directions.
    Keywords:  CiteSpace; citation analysis; patellar dislocation; research hotspots; scientometric analysis
    DOI:  https://doi.org/10.1177/23259671221137051
  34. Front Microbiol. 2022 ;13 1037708
    Global trends in Akkermansia muciniphila research: A bibliometric visualization.
    Zitong Li, Haoran Ke, Ying Wang, Shuze Chen, Xiuying Liu, Qianyun Lin, Pu Wang, Ye Chen.
      Background: Akkermansia muciniphila is a member of the gut microbiome, using mucin as sources of carbon, nitrogen, and energy. Since the first discovery of this unique bacterium in 2004, A. muciniphila has been extensively studied. It is considered a promising "next-generation beneficial microbe." The purpose of this paper is to sort out the research status and summarize the hotspots through bibliometric analysis of the publications of A. muciniphila.Methods: The publications about A. muciniphila from January 2004 to February 2022 were obtained from the Web of Science Core Collection. Visualization analyses were performed using three bibliometric tools and GraphPad Prism.
    Results: A total of 1,478 published documents were analyzed. Annual publication number grew from 1 in 2004 to 336 in 2021, with China being the leading producer (33.36%). De Vos, Willem M was the most productive author with the highest H-index (documents = 56, H-index = 37), followed by Cani, Patrice D (documents = 35, H-index = 25). And Scientific Reports published the most papers. PNAS was the keystone taxa in this field, with high betweenness centrality (0.11) and high frequency. The keywords with high frequency in recent years include: oxidative stress, diet, metformin, fecal microbiota transplantation, short-chain fatty acids, polyphenols, microbiota metabolites and so on. The keyword "oxidative stress" was observed to be increasing in frequency recently.
    Conclusion: Over time, the scope of the research on the clinical uses of A. muciniphila has gradually increased, and was gradually deepened and developed toward a more precise level. A. muciniphila is likely to remain a research hotspot in the foreseeable future and may contribute to human health.
    Keywords:  Akkermansia muciniphila; bibliometrics; gut microbiota; trends; visualization
    DOI:  https://doi.org/10.3389/fmicb.2022.1037708
  35. Front Oncol. 2022 ;12 905868
    A bibliometric and visualization-based analysis of temozolomide research hotspots and frontier evolution.
    Peng Song, Hui Li, Kuo Xu, Zi-Wei Li, Xia Ren, Xian-Jun Fu.
      The literature related to TMZ research in the Web of Science (WOS) database was analyzed using bibliometrics and visualization by Citespace and VOSviewer.The publication status (number of publications, institutions, and frequency of citations), collaborations, and research focus was analyzed to clarify the current situation of TMZ research. And the recent research on TMZ provides a detailed summary. Based on objective data analysis, this study provides a complete analysis portraying the progression of historical milestones in TMZ development and future research directions from various TMZ research domains.
    Keywords:  bibliometrics; development process; glioblastoma; temozolomide; web of science
    DOI:  https://doi.org/10.3389/fonc.2022.905868
  36. J Med Internet Res. 2022 Nov 30.
    The Great Inflation: How COVID-19 affected the Journal Impact Factor of high impact medical journals.
    Panagiotis Giannos, Orestis Delardas.
      BACKGROUND: The journal impact factor (IF) is the leading method of scholarly assessment in today's research world, influencing where scholars submit their research and funders distribute their resources. The Coronavirus disease 2019 (COVID-19), one of the most serious health crises, resulted in an unprecedented surge of publications across all areas of knowledge. An important question is whether COVID-19 affected the "gold standard of scholarly assessment".OBJECTIVE: We aimed to comprehensively compare the productivity trends of COVID-19 and non-COVID-19 literature as well as track their evolution and scholarly impact across three consecutive calendar years.
    METHODS: We took as an example six high impact general medicine journals (Annals, BMJ, Lancet, Nature, NEJM and JAMA) and searched the literature using the Web of Science database for manuscripts published between January 1, 2019 and December 31, 2021. To assess the effect of COVID-19 and non-COVID-19 literature in their scholarly impact, we calculated their annual Ifs and percentage changes. Thereafter, we estimated the citation probability of COVID-19 and non-COVID-19 publications along with their publication and citation rates by journal.
    RESULTS: A significant increase (P=.03) in IF change for COVID-19 manuscripts published from 2019 to 2020 was seen (Annals: 283%, BMJ: 199%, Lancet: 392%, Nature: 80%, NEJM: 196%, JAMA: 208%), against non-COVID-19 ones. The likelihood of highly cited publications was significantly increased in COVID-19 manuscripts from 2019 to 2021 (Annals: Z=3.4, P<.001; BMJ: Z=4.3, P<.001; Lancet: Z=3.5, P<.001; Nature: Z=7.1, P<.001; NEJM: Z=4.7, P<.001; JAMA: Z=3.8, P<.001).The publication and citation rates of COVID-19 publications followed a positive trajectory, as opposed to non-COVID-19. The citation rate for COVID-19 publications peaked 10 months earlier than the publication rate.
    CONCLUSIONS: The rapid surge of COVID-19 publications emphasised the capacity of scientific communities to respond against a global health emergency, yet inflated IFs create ambiguity as benchmark tools for assessing scholarly impact. The immediate implication is a loss in value of and trust on journal IFs as metrics of research and scientific rigour perceived by academia and the society. Loss of confidence towards procedures employed by highly reputable publishers may incentivise authors to exploit the publication process by monopolising their research on COVID-19 and encourage them towards publishing in journals of predatory behaviour.
    CLINICALTRIAL:
    DOI:  https://doi.org/10.2196/43089
  37. Front Psychiatry. 2022 ;13 925273
    Emerging trends in epigenetic and childhood trauma: Bibliometrics and visual analysis.
    Yuting Nie, Lulu Wen, Juexian Song, Ningqun Wang, Liyuan Huang, Li Gao, Miao Qu.
      Background: The epigenetic study of childhood trauma has become a valuable field. However, the evolution and emerging trends in epigenetics and childhood trauma have not been studied by bibliometric methods.Objective: This study aims to evaluate status of epigenetic studies in childhood trauma and reveal the research trends based on bibliometrics.
    Methods: A total of 1,151 publications related to childhood trauma and epigenetics published between 2000 and 2021 were retrieved from the Web of Science Core Collection (WoSCC). CiteSpace (5.8. R 3) was used to implement bibliometric analysis and visualization.
    Results: Since 2010, the number of related publications has expanded quickly. The United States and McGill University are the most influential countries and research institutes, respectively. Elisabeth Binder is a leading researcher in childhood trauma and epigenetic-related research. Biological Psychiatry is probably the most popular journal. In addition, comprehensive keyword analysis revealed that "glucocorticoid receptor," "brain development," "epigenetic regulation," "depression," "posttraumatic stress disorder," "maternal care," "histone acetylation," "telomere length," "microRNA," and "anxiety" reflect the latest research trends in the field. A comprehensive reference analysis demonstrated NR3C1 gene methylation, FKBP5 DNA methylation, BDNF DNA methylation, and KITLG methylation have been hot spots in epigenetic studies in the field of childhood trauma in recent years. Notably, the relationship between childhood adversity and NR3C1 gene methylation levels remains unresolved and requires well-designed studies with control for more confounding factors.
    Conclusion: As the best of our knowledge, this is the first bibliometric analysis of the association between childhood trauma and epigenetics. Our analysis of the literature suggests that childhood trauma may induce depression, anxiety, and post-traumatic stress disorder through epigenetic regulation of glucocorticoid receptor expression and brain development. The hypothalamic-pituitary-adrenal axis is the key points of epigenetic research. The current researches focus on NR3C1 gene methylation, FKBP5 DNA methylation, BDNF DNA methylation, and KITLG methylation. These results provide a guiding perspective for the study of epigenetic effects of childhood trauma, and help researchers choose future research directions based on current keywords.
    Keywords:  CiteSpace; DNA methylation; childhood trauma; epigenetics; visual analysis
    DOI:  https://doi.org/10.3389/fpsyt.2022.925273
  38. J Gastroenterol Hepatol. 2022 Dec 02.
    A Bibliometric and Visualized Analysis of Liver Fibrosis From 2002 to 2022.
    Qianqian Zhao, Luhua Liang, Fei Zhai, Guixia Ling, Rongwu Xiang, Xiwei Jiang.
      Fibrosis of the liver is a degenerative alteration that occurs in the majority of chronic liver disorders. Further progression can lead to cirrhosis, liver failure, and hepatocellular carcinoma, which can seriously affect the health and lives of patients. The field of liver fibrosis research has flourished in the last 20 years, with approximately 9,000 articles retrieved from the Web of Science Core Collection database alone. In order to identify future research hotspots and potential paths in a thorough and scientifically reliable manner, it is important to organize and visualize the research on this topic from a holistic and very general perspective. This study used bibliometric analysis with CiteSpace and VOSviewer software to provide a quantitative analysis, hotspot mining, and commentary of articles published in the field of liver fibrosis over the last 20 years. This bibliometric analysis contains a total of 8,994 articles with 45,667 authors from 6,872 institutions in 97 countries, published in 1,371 journals and citing 156,309 references. The literature volume has steadily increased over the last 20 years. Research has focused on gastroenterology & hepatology, pharmacology & pharmacy, and medicine, research & experimental areas. We found that the pathological mechanisms, diagnostic and quantitative methods, etiology, and anti-fibrotic strategies constitute the knowledge structure of liver fibrosis. Finding mechanisms for liver fibrosis regression, identifying precise non-invasive diagnostic and prognostic biomarkers, and creating efficient liver fibrosis patient treatments are the main goals of current research.
    Keywords:  Bibliometrics; CiteSpace; Liver fibrosis; VOSviwer
    DOI:  https://doi.org/10.1111/jgh.16081
  39. Front Cardiovasc Med. 2022 ;9 991503
    Trends in research on sick sinus syndrome: A bibliometric analysis from 2000 to 2022.
    Xin'ai Zhang, Yong Zhao, Yutong Zhou, Jiayu Lv, Jiaran Peng, Haiyan Zhu, Ruxiu Liu.
      Sick sinus syndrome (SSS) is a refractory arrhythmia disease caused by the pathological changes of sinoatrial node and its adjacent tissues. 2,251 publications related to SSS were retrieved from Web of Science database from 2000 to 2022 and analyzed by using VOS viewer and CiteSpace software. The results showed the United States dominated the field, followed by Japan, Germany, and China. SSS was closely related to risk factors such as atrial fibrillation and aging. Sick sinus syndrome, atrial fibrillation and sinus node dysfunction were the top three keywords that had the strongest correlation with the study. Pacemaker implantation, differentiation and mutation are research hotspots currently. Clinical studies on SSS found that sick sinus syndrome, atrial fibrillation, and pacemakers were the top three keywords that had the largest nodes and the highest frequency. In the field of basic applied research and basic research, atrial fibrillation and pacemaker cells were the focus of research. In conclusion, bibliometric analysis provided valuable information for the prevention, treatment and future research trends of SSS.
    Keywords:  CiteSpace; VOS viewer; bibliometric; sick sinus syndrome; sinus node dysfunction
    DOI:  https://doi.org/10.3389/fcvm.2022.991503
  40. Front Psychiatry. 2022 ;13 1022472
    The schizophrenia and gut microbiota: A bibliometric and visual analysis.
    Chao Yang, Xiaoxiao Lin, Xianteng Wang, Huanzhong Liu, Jinyu Huang, Shuai Wang.
      Background: Many studies have explored the link between the gut microbiota and schizophrenia. To date, there have been no bibliometric analyses to summarize the association between the gut microbiota and schizophrenia. We aimed to conduct a bibliometric study of this association to determine the current status and areas for advancement in this field.Materials and methods: Publications related to the gut microbiota and schizophrenia were retrieved from the Web of Science Core Collection (WoSCC). The WoSCC literature analysis wire and VOSviewer 1.6.16 were used to conduct the analysis.
    Results: In total, 162 publications were included in our study. The publications generally showed an upward trend from 2014. A total of 873 authors from 355 organizations and 40 countries/regions contributed to this field. The leading authors were Timothy Dinan, John F Cryan, and Emily Severance. The leading institutions were Johns Hopkins University, the University College Cork, and the University of Toronto. The most productive countries were the United States (US), China, and Canada. In total, 95 journals contributed to this field. Among them, the top three productive journals were Schizophrenia Research, Progress in Neuro Psychopharmacology Biological Psychiatry, and Frontiers in Psychiatry. The important keywords in the clusters were gut microbiome, bipolar disorder, schizophrenia, antipsychotics, weight gain, metabolic syndrome, gut-brain axis, autism, depression, inflammation, and brain.
    Conclusion: The main research hotspots involving the connection between schizophrenia and the gut microbiota were the characteristics of the microbiota composition in schizophrenia patients, the gut-brain axis, and microbial-based interventions for schizophrenia. The studies about the association between gut microbiota and schizophrenia are limited, and more studies are needed to provide new insights into the gut microbiota in the pathogenesis and treatment of schizophrenia.
    Keywords:  antipsychotics; bibliometric analysis; gut microbiota; gut-brain axis; schizophrenia
    DOI:  https://doi.org/10.3389/fpsyt.2022.1022472
  41. SAGE Open Med. 2022 ;10 20503121221129921
    The 50 most impactful articles on the medial ulnar collateral ligament: An altmetric analysis of online media.
    Kunal M Kirloskar, Matthew D Civilette, William R Rate, Andrew S Cohen, Brett D Haislup, Suresh K Nayar, Blake M Bodendorfer, Heath P Gould.
      The purpose of this study was to use the Altmetric Attention Score to determine the 50 most impactful medial ulnar collateral ligament articles in online media and compare their characteristics to the most-cited medial ulnar collateral ligament articles in the scientific literature. The Altmetric database was queried to identify all published articles about the medial ulnar collateral ligament, and this list was stratified by the Altmetric Attention Score to identify the 50 highest scoring articles. Several data elements were extracted, including article topic, article type, journal name, and the number of online mentions on Facebook, Twitter, news, and other platforms. Each article's geographic origin was determined based on the institutional affiliation of the first author. Our index search yielded 1283 articles published between 1987 and 2020, from which the 50 articles with the highest Altmetric Attention Scores were included for analysis. Altmetric Attention Scores of the top 50 medial ulnar collateral ligament articles ranged from 20 to 482 (median: 32, interquartile range: 20-62). The most common article type was original research (72%), and the most common topic was epidemiology/risk factors (26%). A majority of studies were Level 3 (36%) or Level 4 evidence (36%). Of the top 50 medial ulnar collateral ligament articles, 94% originated from the United States. A few articles had a high Altmetric Attention Score, suggesting that medial ulnar collateral ligament research does not generate consistently high online attention. The lack of Level 1 studies suggests the need for high-level studies on the medial ulnar collateral ligament. Most studies originated in the United States and were published in the American Orthopaedic Society for Sports Medicine-affiliated journals. The medial ulnar collateral ligament articles included in this study differed substantially from a previous report of the most-cited medial ulnar collateral ligament articles in the literature, suggesting that alternative metrics add a unique dimension to understanding the overall impact of published research on the medial ulnar collateral ligament.
    Keywords:  AAS; MUCL; Medial ulnar collateral ligament; altmetric attention score; altmetrics; bibliometrics; citation rate
    DOI:  https://doi.org/10.1177/20503121221129921
  42. Chemosphere. 2022 Nov 23. pii: S0045-6535(22)03835-8. [Epub ahead of print]313 137342
    Trends in dithiocarbamates food research: A bibliometric vision.
    José Manuel Veiga-Del-Baño, Salvadora Martínez-López, Gabriel Pérez-Lucas, Juan José Cuenca-Martínez, Pedro Andreo-Martínez.
      Dithiocarbamate Fungicides (DTFs) are widely analyzed and studied mainly due to the fact that they play an important role in the cultivation of fruits and vegetables. This manuscript aims to display the results of a bibliometric analysis based on the Web of Science© database, performed in the DTF and food research area. A total of 374 publications were examined. The most scientific production was concentrated between 2012 and 2021, showing a decrease of 32% over the last two years. The Journal of Agricultural and Food Chemistry, India, and Sardar Vallabhbhai National Institute of Technology were the most productive journal, country, and institution, respectively. Reference Publication Year Spectroscopy index showed a decrease of 95% in the last last years studied. Finally, current and future trends should focus on keywords such as individual DTF (Mancozeb, Thiram and Maneb), metabolites (Ethylenethiourea, Propilenthiourea) and a change in the analysis methodology: HPLC versus traditional GC.
    Keywords:  Bibliometric review; Dithiocarbamates; Food; Fungicides; GC; HPLC
    DOI:  https://doi.org/10.1016/j.chemosphere.2022.137342
  43. Acta Trop. 2022 Nov 28. pii: S0001-706X(22)00474-0. [Epub ahead of print] 106783
    Advances in research on schistosomiasis and toxoplasmosis in China: a bibliometric analysis of Chinese academic journals published from 1980 to 2021.
    Yiran Tao, Chunxiang Shen, Yu Zhang, Xinyu Zhao, Jian Wu, Minjun Ji, Zhipeng Xu.
      BACKGROUND: The scale-up of zoonotic parasite control in China, coupled with numerous academic articles in Chinese journals has led to the development of new tools and strategies aimed at further consolidating parasite control goals. As a result, there is a growing need for an up-to-date understanding of the research progress and prevention and control experience of parasitic diseases in China.METHODS: To understand the research status of schistosomiasis and toxoplasmosis in China, academic articles published in Chinese journals from 1980 to 2021 were retrieved from China National Knowledge Infrastructure (CNKI) and Wanfang databases. The Bibliographic Items Co-occurrence Matrix Builder (BICOMB) software was used to extract and analyze the keyword frequencies. The 'K/A ratio' as the frequency of a keyword that occurred in all the articles within a certain time stage was calculated to compare the popularity of the same keyword in different time stages. Keyword co-occurrence network maps were constructed by VOSviewer software.
    RESULTS: A total of 18,508 articles in the research field of Schistosoma and 13,289 articles in the field of Toxoplasma gondii were included. Results in both fields showed some similarities: the annual number of articles presented an increasing trend before entering the 21st century and decreased rapidly in recent years. Two opposite changing trends of keyword frequency could be observed in the K/A ratio analysis: the K/A ratios of 'Surveillance' and 'Infection' continuously increased over time, while those of 'Schistosoma mansoni' and 'Mesenteric lymph nodes' decreased. The diversification of keyword co-occurrence networks could be observed in the co-occurrence network maps.
    CONCLUSIONS: This bibliometric analysis reveals trends in research themes in the fields of Schistosoma and Toxoplasma gondii from 1980 to 2021, presenting China's experience such as a high degree of government involvement and multidisciplinary participation in schistosomiasis and toxoplasmosis control and elimination.
    Keywords:  Bibliometric analysis; Schistosoma japonicum; Schistosomiasis; Toxoplasma gondii; Toxoplasmosis
    DOI:  https://doi.org/10.1016/j.actatropica.2022.106783
  44. Front Nutr. 2022 ;9 1060436
    Bibliometric and visual analysis in the field of ketogenic diet on cancer from 2012 to 2021.
    Rongrong Li, Qingcheng Huang, Chenxiao Ye, Changhong Wu, Ning Luo, Yi Lu, Jianqiao Fang, Yun Wang.
      Increasing evidence demonstrated that the ketogenic diet (KD) played a positive effect on cancer treatment. However, no systematic review and bibliometric analysis were conducted in this field. This study aimed to explore the current status, and reveal the potential trends and hotspots to provide a reference for future research. Publications were extracted from the Web of Science Core Collection. CiteSpace (5.6.R3) software and the website of bibliometrics were used for visual analysis. A total of 500 publications with 334 articles and 166 reviews were included, with the timespan of 2012 to 2021. The United States was the most productive country. Majority of the top 10 institutions were from the United States, and Harvard University was the top-contributing institution. The most prolific author and the co-cited author was Thomas N Seyfried from Boston College. The highest cited reference was published in PLoS ONE, authored by Abdelwahab Mohammed G, with 161 citations. Glioma and breast cancer were the most common types of cancer in this field, while hepatocellular carcinoma and pancreatic cancer were the new hotspots. The anti-tumor mechanism of KD mainly focused on regulating metabolism, decanoic acid, oxidative stress, fatty acid oxidation, and cell apoptosis. Additionally, the presence of "chemotherapy" and "radiotherapy" in the keywords indicated that KD combined with anti-tumor research was a topic, while "immunotherapy" has became a recent frontiers. Notably, as a metabolic therapy, KD was deserved more attention in the treatment of hepatocellular carcinoma and pancreatic cancer, and KD combined with immunotherapy was the new hotspot and frontier. Additionally, more molecular studies and high-quality uniformly, randomized, controlled clinical trials are urgently warranted to evaluate the effect of KD in multiple cancers.
    Keywords:  bibliometric analysis; cancer; clinical trials; immunotherapy; ketogenic diet; mechanism
    DOI:  https://doi.org/10.3389/fnut.2022.1060436
  45. Circ J. 2022 Nov 30.
    The Circulation Journal Official Impact Factor and the Most Frequently Cited Papers in 2021.
    Toshihisa Anzai.
      
    DOI:  https://doi.org/10.1253/circj.CJ-66-0208
  46. BMJ. 2022 Nov 28. 379 e071517
    Retracted papers originating from paper mills: cross sectional study.
    Cristina Candal-Pedreira, Joseph S Ross, Alberto Ruano-Ravina, David S Egilman, Esteve Fernández, Mónica Pérez-Ríos.
      OBJECTIVES: To describe retracted papers originating from paper mills, including their characteristics, visibility, and impact over time, and the journals in which they were published.DESIGN: Cross sectional study.
    SETTING: The Retraction Watch database was used for identification of retracted papers from paper mills, Web of Science was used for the total number of published papers, and data from Journal Citation Reports were collected to show characteristics of journals.
    PARTICIPANTS: All paper mill papers retracted from 1 January 2004 to 26 June 2022 were included in the study. Papers bearing an expression of concern were excluded.
    MAIN OUTCOME MEASURES: Descriptive statistics were used to characterise the sample and analyse the trend of retracted paper mill papers over time, and to analyse their impact and visibility by reference to the number of citations received.
    RESULTS: 1182 retracted paper mill papers were identified. The publication of the first paper mill paper was in 2004 and the first retraction was in 2016; by 2021, paper mill retractions accounted for 772 (21.8%) of the 3544 total retractions. Overall, retracted paper mill papers were mostly published in journals of the second highest Journal Citation Reports quartile for impact factor (n=529 (44.8%)) and listed four to six authors (n=602 (50.9%)). Of the 1182 papers, almost all listed authors of 1143 (96.8%) paper mill retractions came from Chinese institutions and 909 (76.9%) listed a hospital as a primary affiliation. 15 journals accounted for 812 (68.7%) of 1182 paper mill retractions, with one journal accounting for 166 (14.0%). Nearly all (n=1083, 93.8%) paper mill retractions had received at least one citation since publication, with a median of 11 (interquartile range 5-22) citations received.
    CONCLUSIONS: Papers retracted originating from paper mills are increasing in frequency, posing a problem for the research community. Retracted paper mill papers most commonly originated from China and were published in a small number of journals. Nevertheless, detected paper mill papers might be substantially different from those that are not detected. New mechanisms are needed to identify and avoid this relatively new type of misconduct.
    DOI:  https://doi.org/10.1136/bmj-2022-071517
  47. World Neurosurg. 2022 Nov 28. pii: S1878-8750(22)01677-1. [Epub ahead of print]
    Exosome-Based Therapy for Ischemic Stroke: A Bibliometric Analysis of Current Trends and Future Directions.
    Braxton R Schuldt, Roshini Kalagara, Susmita Chennareddy, Ian C Odland, Margaret H Downes, Emma Reford, James M Vicari, Muhammad Ali, Abhiraj D Bhimani, David Putrino, Christopher P Kellner.
      INTRODUCTION: Stroke is a leading cause of mortality and disability worldwide. Exosomes, or small extracellular vesicles with signaling properties, have recently been identified as novel mechanisms for stroke treatment. This study aims to use bibliometric techniques to identify current research trends and future directions of exosome-based stroke therapy.METHODS: The Web of Science Core Collection (WOSCC) was searched using terms that included "exosome" and all stroke types. Bibliometric data, including authors, publication years, citations, countries/regions, institutions, journals, and Keywords Plus, were extracted directly from the WOSCC. Keywords were mapped using VOSviewer.
    RESULTS: 424 documents were identified from 2010-2021 with a total of 12,708 citations. The number of publications increased yearly from 2012-2021, the majority of which were research and review articles. China and the United States produced the most publications with Henry Ford Hospital and Oakland University serving as the two most highly published research institutions. Documents were published most frequently in the journal Stroke. Keywords Plus analyses revealed three main research areas: exosomes as pathogenic mediators, biomarkers, and treatments of stroke. Ischemic stroke was the most prevalent type of stroke included in these studies.
    CONCLUSIONS: Using bibliometric techniques, this study identified a current and growing interest in the research of exosomes in stroke, particularly in their pathogenic, biomarker, and potential minimally invasive therapeutic properties. Given the high prevalence of ischemic stroke in the current literature, further characterization of exosomes in other stroke types, such as intracerebral hemorrhage, emerges as a future direction for this field of research.
    Keywords:  Exosome; Intervention; Stroke; Technology
    DOI:  https://doi.org/10.1016/j.wneu.2022.11.125
  48. Front Plant Sci. 2022 ;13 1052660
    Plant responses to high temperature and drought: A bibliometrics analysis.
    Yong Cui, Shengnan Ouyang, Yongju Zhao, Liehua Tie, Changchang Shao, Honglang Duan.
      Global climate change is expected to further increase the frequency and severity of extreme events, such as high temperature/heat waves as well as drought in the future. Thus, how plant responds to high temperature and drought has become a key research topic. In this study, we extracted data from Web of Science Core Collections database, and synthesized plant responses to high temperature and drought based on bibliometric methods using software of R and VOSviewer. The results showed that a stabilized increasing trend of the publications (1199 papers) was found during the period of 2008 to 2014, and then showed a rapid increase (2583 papers) from year 2015 to 2021. Secondly, the top five dominant research fields of plant responses to high temperature and drought were Plant Science, Agroforestry Science, Environmental Science, Biochemistry, and Molecular Biology, respectively. The largest amount of published article has been found in the Frontiers in Plant Science journal, which has the highest global total citations and H-index. We also found that the journal of Plant Physiology has the highest local citations. From the most cited papers and references, the most important research focus was the improvement of crop yield and vegetation stress resistance. Furthermore, "drought" has been the most prominent keyword over the last 14 years, and more attention has been paid to "climate change" over the last 5 years. Under future climate change, how to regulate growth and development of food crops subjected to high temperature and drought stress may become a hotspot, and increasing research is critical to provide more insights into plant responses to high temperature and drought by linking plant above-below ground components. To summarize, this research will contribute to a comprehensive understanding of the past, present, and future research on plant responses to high temperature and drought.
    Keywords:  bibliometric analysis; drought stress; high temperature stress; plant; plant responses; yield
    DOI:  https://doi.org/10.3389/fpls.2022.1052660
  49. J Med Imaging Radiat Oncol. 2022 Nov 29.
    Trends in gender of first and senior authors of articles published in JMIRO.
    Vikneswary Batumalai, Shivani Kumar, Puma Sundaresan.
      INTRODUCTION: Despite progress of women in science and medicine, women remain underrepresented in academic publication. The aim of this study was to evaluate potential gender differences in women authorship in the Journal of Medical Imaging and Radiation Oncology (JMIRO).METHODS: Gender of the first and senior author of all articles published in JMIRO between 2012 and 2021 were examined. Changes over time and differences among groups were compared using the chi-square test.
    RESULTS: In total, 1,138 articles were assessed. Women were first and senior authors on 34% and 25% of all articles respectively. The proportion of women as first author was 30%, 41% and 36% for medical imaging (MI), radiation oncology (RO) and combined MI/RO articles respectively. Similarly, the proportion of women as senior author was lower than men at 22%, 32% and 23% for MI, RO and MI/RO articles respectively. Women first authorship over the study period remained stable from 2014 (36%) to 2020 (38%); however, it decreased dramatically in 2021 to 28%. There was a trend of increasing women senior authorship from 2013 (15%) to 2017 (35%) but decreased to 23% in 2021.
    CONCLUSION: Over the past 10 years of publications, one in three first authors were women and only one in four senior authors were women. The acknowledgement of this imbalance is the first step to pave the way towards addressing underlying systemic issues related to academic publication and disparities in gender and other inequities.
    Keywords:  diversity; gender equity; inclusion; medical imaging; radiation oncology
    DOI:  https://doi.org/10.1111/1754-9485.13492
  50. Front Cell Infect Microbiol. 2022 ;12 1057492
    Bibliometric and visual analysis of fecal microbiota transplantation research from 2012 to 2021.
    Fengwei Zhang, Peilin Yang, Yilin Chen, Ruirui Wang, Baocheng Liu, Jianying Wang, Min Yuan, Lei Zhang.
      Background: Fecal microbiota transplantation (FMT) is an emerging therapy for diseases associated with intestinal flora imbalance that has attracted increasing attention in recent years. This study aims to provide an overview of research trends in the field, and act as a reference point for future scientific research by analyzing the state of current research, identifying hotspots, and potential frontiers of FMT.Methods: Articles relating to FMT that were published between the years 2012 and 2021 were retrieved from the Web of Science Core Collection. Bibliometric analysis was performed using Microsoft Excel and CiteSpace.
    Results: A total of 2,403 English language articles relating to FMT research were published over the last ten years. Most of this research was carried out in the United States of America, with Harvard Medical school being the most productive institution. Much of the research was published in the PLoS One journal. Alexander Khoruts was identified as a prominent, productive researcher in the field. Keyword analysis revealed that research hot spots included gut microbiota, Clostridium difficile infection (CDI), and diseases. Burst detection indicated that future research frontiers include clinical practice guidelines and strategies.
    Conclusion: Our analysis explored hot spots and emerging trends in the FMT field. Indications for use of FMT extended from digestive system diseases to other systemic diseases. Additionally, areas such as risk assessment and control, along with application methods were also a focus of current research. Moreover, research relating to optimization of clinical practice has excellent prospects.
    Keywords:  CiteSpace; bibliometric; clostridium difficile infection; fecal microbiota transplantation; gut microbiota
    DOI:  https://doi.org/10.3389/fcimb.2022.1057492
  51. Pediatr Radiol. 2022 Nov 29.
    Gender disparity in academic advancement: exploring differences among adult and pediatric radiologists.
    Samantha M Schilling, Andrew T Trout, Rama S Ayyala.
      BACKGROUND: Gender imbalance in research output and academic rank in academic radiology is well-documented and long-standing. Less is known regarding this imbalance among pediatric radiologists.OBJECTIVE: To characterize gender differences for academic rank and scholarly productivity of pediatric radiologists relative to adult radiologists.
    MATERIALS AND METHODS: During summer 2021, faculty data for the top 10 U.S. News & World Report ranked adult radiology programs and the top 12 largest pediatric hospital radiology departments were collected. Information regarding self-reported gender, age, years of practice and academic rank was accessed from institutional websites and public provider databases. The h-index and the number of publications were acquired via Scopus. Group comparisons were performed using Mann-Whitney and chi-square tests.
    RESULTS: Three hundred and sixty-four (160 women) pediatric and 1,170 (468 women) adult radiologists were included. Compared to adult radiologists, there were significantly fewer pediatric radiologists in advanced ranks (associate or full professor) (P = 0.024), driven by differences between male (P = 0.033) but not female radiologists (P = 0.67). Among pediatric radiologists, there was no significant difference in years in practice (P = 0.29) between males and females. There also was no significant difference in academic rank by gender (P = 0.37), different from adult radiology where men outnumber women in advanced ranks (P < 0.001). Male pediatric radiologists displayed higher academic productivity (h-index: 9.0 vs. 7.0; P = 0.01 and number of publications: 31 vs. 18; P = 0.003) than their female colleagues.
    CONCLUSION: Academic pediatric radiology seems to have more equitable academic advancement than academic adult radiology. Despite similar time in the workforce, academic output among female pediatric radiologists lags that of their male colleagues.
    Keywords:  Academic advancement; Adult; Gender; Pediatric radiology; Publications
    DOI:  https://doi.org/10.1007/s00247-022-05547-9
  52. Aesthetic Plast Surg. 2022 Dec 02.
    Global Analyses and Latest Research Hot Spots of Adipose-Derived Stem Cells in Fat Grafting: A Bibliometric and Visualized Review.
    Tian-Hao Li, Zi-Ming Li, Xiao-Han Qin, Nan-Ze Yu, Jiu-Zuo Huang, Xiao Long.
      BACKGROUND: Fat grafting is one of the most effective treatments for soft tissue restoration and augmentation. Adipose-derived stem cells (ASCs) supplementation is one of the foremost concerns to improve its efficiency. There have been several studies aiming at adipose-derived mesenchymal stem cells in fat grafting, but no relevant bibliometric research has conducted.METHODS: Articles about fat grafting and ASCs were retrieved in Web of Science Core Collection (WoSCC). Using VOSviewer 1.6.10.0 (Leiden University, the Netherlands) and CiteSpace 6.1.R2 (Drexel University, USA), the information of national distribution, institutions, journals, authors and keywords were evaluated and calculated.
    RESULTS: A total of 1166 papers in the field of ASCs in fat grafting were retrieved from 2002 to 2021. The USA produced the most articles, and the top 2 productive institutions were all from the USA. Researchers and institutions conducting ASCs in fat grafting research have shown a widespread and close connection. Plastic and Reconstructive Surgery published the most article on ASCs in fat grafting, and professor Rubin Peter is the most productive author. The top 10 references with the highest LCS mainly focused on applying ASCs to assist fat transplantation in plastic surgery. The most cited keywords formed 4 clusters, and "mesenchymal stem," "mesenchymal stromal cell," "stromal vascular fraction" and "long term" were the most recently trending keywords.
    CONCLUSIONS: This article provides a summary of the current research status focusing on fat grafting and ASCs. More efforts will be made to promote the application of ASCs in fat grafting.
    LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  Adipose-derived stem cells; Bibliometric; Fat grafting; Lipoinjection
    DOI:  https://doi.org/10.1007/s00266-022-03201-1
  53. Front Psychol. 2022 ;13 1033872
    LDA-based topic modeling for COVID-19-related sports research trends.
    Jea Woog Lee, YoungBin Kim, Doug Hyun Han.
      Introduction: The COVID-19 pandemic could generate a turning point for introducing a new system for sports participation and business. The purpose of this study is to explore trends and topic structures of COVID-19-related sports research by analyzing the relevant literature.Methods: Sports studies related to COVID-19 were collected in searching international academic databases. After the pre-processing step using the refinement and morpheme analysis function of the Net Miner program, topic modeling and social network analysis were used to analyze Journal Citation Reports found using the search term 'COVID-19 sports'.
    Results: As a result, this study used subject modeling to reveal important potential topics in COVID-19-related sports research articles. 'Sports participation', 'elite players', and 'sports industry' were macroscopically classified, and detailed research topics could be identified from each division.
    Conclusion: This study revealed important latent topics from COVID-19-related sports research articles using topic modeling. The results of the research elucidate the structure of academic knowledge on this topic and provide guidance for future research.
    Keywords:  COVID-19; LDA algorithm; data science; research trend; sport; topic modeling
    DOI:  https://doi.org/10.3389/fpsyg.2022.1033872
  54. Int Rev Financ Anal. 2023 Jan;85 102458
    COVID-19 and finance scholarship: A systematic and bibliometric analysis.
    Sabri Boubaker, John W Goodell, Satish Kumar, Riya Sureka.
      COVID-19 has posed unprecedented challenges to global finances because of its unparalleled global scope, with both concomitant shocks as well as the likely altering of risk assessments and forecasts for the foreseeable future. As the effects of COVID-19 on financial markets and institutions have been widely addressed by various literature, we systematically synthesize this literature. Through a comprehensive search process, we extract and review 818 articles. Appling bibliometric methods, we explore the trends among various research constituents involved in the field. Using multi-dimensional scaling, we identify the intellectual structure of research in the domain and outline four distinct themes. We also identify the evolution and shifts in research within the short span of three years since the inception of COVID-19. Through detailed content analysis, various future research directions are proposed.
    Keywords:  Bibliometric analysis; COVID-19; Finance literature; Systematic literature review; Systematic review
    DOI:  https://doi.org/10.1016/j.irfa.2022.102458
  55. World Neurosurg. 2022 Nov 25. pii: S1878-8750(22)01642-4. [Epub ahead of print]
    A Bibliometric Review: Brain Tumour MRIs using different CNN Architectures.
    Arati Rath, Dipak Kumar Mohanty, Bhabani Shankar Prasad Mishra, Dilip Kumar Bagal.
      Numerous scientists and researchers have been developing advanced procedures and methods for diagnosing the kind and phase of a human tumour. Brain tumours, which are neoplastic and abnormal developments of brain cells, are one of the most prominent causes of death. Brain tumours, also known as lesions or neoplasia, may be roughly classified as either primary or metastatic. Primary brain tumours arise from brain tissue and its surrounding environment. The recognition of brain tumours using magnetic resonance images (MRIs) via a deep learning technique such as Convolutional Neural Network (CNN) has garnered significant academic interest over the last few decades. In this study, a detailed evaluation based on bibliometrics is considered in order to synthesise and organise the available academic literature and to identify current research trends and hotspots. We used bibliometric methodologies and a literature review for the CNN-based Brain Tumor to synthesise and evaluate prior studies. For this bibliometric analysis, we applied the Visualization of Similarity Viewer (VOSviewer) programme to classify the major publications, notable journals, financial sponsors, and affiliations. In conclusion, we suggest that one of the next paths of study will be the incorporation of other databases to advance CNN-based brain tumour identification from MRIs.
    Keywords:  Brain Tumor; CNN; Deep Learning; MRI
    DOI:  https://doi.org/10.1016/j.wneu.2022.11.091
  56. Chemosphere. 2022 Nov 23. pii: S0045-6535(22)03850-4. [Epub ahead of print]313 137357
    Comment on "research on the remediation of cesium pollution by adsorption: Insights from bibliometric analysis".
    Waseem Hassan.
      
    DOI:  https://doi.org/10.1016/j.chemosphere.2022.137357
  57. BMC Musculoskelet Disord. 2022 Nov 26. 23(1): 1016
    Effects of mitochondrial dysfunction on bone metabolism and related diseases: a scientometric study from 2003 to 2022.
    Wei Zhang, Chang-Liang Xia, Jun-Nan Ma, Jia-Xuan Li, Qi Chen, Shuan-Ji Ou, Yang Yang, Yong Qi, Chang-Peng Xu.
      BACKGROUND: In recent years, mitochondrial dysfunction has been extensively studied and published, but research on the effects of mitochondrial dysfunction on bone metabolism and related diseases is only just beginning. Furthermore, no studies have been carried out to systematically illustrate this area from a scientometric point of view. The goal of this research is to review existing knowledge and identify new trends and possible hotspots in this area.METHODS: All publications related to the relationship between mitochondrial dysfunction and bone metabolism and related diseases from 2003 to 2022 were searched at the Web of Science Core Collection (WoSCC) on May 7, 2022. Four different analytical tools: VOSviewer 1.6.18, CiteSpace V 6.1, HistorCite (12.03.07), and Excel 2021 were used for the scientometric research.
    RESULTS: The final analysis included 555 valid records in total. Journal of Biological Chemistry (Co-citations = 916) is the most famous journal in this field. China (Percentage = 37%), the United States (Percentage = 24%), and Korea (Percentage = 12%) are the most productive countries. Blanco FJ and Choi EM are the main researchers with significant academic influence. Current research hotspots are basic research on mitochondrial dysfunction and the prevention or treatment of bone metabolism-related diseases.
    CONCLUSION: The study of the consequences of mitochondrial dysfunction on bone metabolism and associated diseases is advancing rapidly. Several prominent researchers have published extensive literature and are widely cited. Future research in this area will focus on oxidative stress, aging, gene expression, and the pathogenesis of bone metabolism-related diseases.
    Keywords:  Bone metabolic diseases; Bone metabolism; Mitochondrial dysfunction; Osteoarthritis
    DOI:  https://doi.org/10.1186/s12891-022-05911-8
  58. Eur J Nucl Med Mol Imaging. 2022 Nov 28.
    Current research topics in FAPI theranostics: a bibliometric analysis.
    Andor F van den Hoven, Ruth G M Keijsers, Marnix G E H Lam, Andor W J M Glaudemans, Frederik A Verburg, Wouter V Vogel, Jules Lavalaye.
      PURPOSE: The study aimed to provide a comprehensive bibliometric overview of the current scientific publications on fibroblast activation protein inhibitor (FAPI) positron emission tomography imaging and radionuclide therapy.METHODS: A PubMed search was performed to identify all MEDLINE-indexed publications on FAPI imaging and radionuclide therapy. The last update was performed on 31 May 2022. An online database of this literature was created, and hierarchical topic-related tags were subsequently assigned to all relevant studies. Frequency analysis was used to evaluate the distribution of the following characteristics: first author's country of origin, journal of publication, study design, imaging techniques and radiopharmaceutical used, histopathological correlation, the type of cancer, and benign disease/uptake types evaluated.
    RESULTS: A total of 294 relevant publications on original studies were identified, consisting of 209 (71%) case reports/series and 85 cohort studies (29%). The majority of studies focused on imaging topics, predominantly comparing uptake on FAPI-PET/CT with 2-[18F]FDG-PET/CT, anatomical imaging, and/or histopathology results. 68% of studies focused on malignancies, with gastro-intestinal cancer, hepato-pancreato-biliary cancer, mixed cancers/metastases, lung cancer, sarcoma, head and neck cancer, and breast cancer being the most frequently reported. 42% of studies focused on benign disease categories, with cardiovascular, musculoskeletal, HPB, head and neck, and IgG4-related disease as most common categories. 16/294 (5%) studies focused on radionuclide therapy, with preliminary reports of acceptable toxicity profiles, tumour activity retention, and suggestion of disease control.
    CONCLUSION: FAPI research is rapidly expanding from diagnostic studies in malignancies and benign diseases to the first reports of salvage radionuclide therapy. The research activity needs to shift now from low-level-of-evidence case reports and series to prospectively designed studies in homogenous patient groups to provide evidence on how and in which clinical situations FAPI theranostics can be of added value to clinical care. We have provided an overview of current research topics to build upon.
    Keywords:  Bibliometric analysis; FAPI theranostics; Positron emission tomography imaging
    DOI:  https://doi.org/10.1007/s00259-022-06052-9
  59. Front Big Data. 2022 ;5 1045513
    TELS: Evolution patterns of research keywords from the evidence of PNAS Social Sciences topics.
    Bing Liu, Mengfan Shi, Yi Kuang, Xin Jiang.
      By reviewing scientific literature, researchers may obtain a comprehensive understanding of field developments, keeping abreast of the current research status and hotspot shifts. The evolution pattern of keywords is supposed to be an efficient indicator in revealing the shifting and sustainability configuration of scientific concepts, ideas, and research hotspots. Here we take an extensive investigation of the evolution of keywords among all publications in PNAS Social Sciences from 1990 to 2021. Statistical tests show the keyword mention time series always accompanied by the emergence of a log-normal distribution. Additionally, we introduce a novel schema of four patterns (TELS), which are Transient impact type, Explosive impact type, Large impact type, and Small impact type, respectively, to illustrate the evolution of keywords. The TELS schema can be used to capture the whole life circle feature of any proposed keyword, from a pool of candidates. By dividing the entire time into four periods, we also introduce the concept of elite keywords to reveal the temporal feature of social sciences focus. An explicit transition from anthropology research to neuroscience and social problems research can be observed from the evolution diagram. We argue that the proposed method is of general sense and might be applicable to other fields of science.
    Keywords:  elite keywords; keyword analysis; keywords evolution pattern; keywords novelty; log-normal distribution
    DOI:  https://doi.org/10.3389/fdata.2022.1045513
  60. Front Genet. 2022 ;13 1041078
    Diverse roles of the CIPK gene family in transcription regulation and various biotic and abiotic stresses: A literature review and bibliometric study.
    Chen Yang, Jin Yi-Feng, Wang Yushu, Gao Yansong, Wang Qi, You Xue.
      CIPKs are a subclass of serine/threonine (Ser/Thr) protein kinases. CBLs are ubiquitous Ca2+ sensors that interact with CIPK with the aid of secondary Ca2+ messengers for regulation of growth and development and response to stresses faced by plants. The divergent roles of the CIPK-CBL interaction in plants include responding to environmental stresses (salt, cold, drought, pH, ABA signaling, and ion toxicity), ion homeostasis (K+, NH4 +, NO3 -, and microelement homeostasis), biotic stress, and plant development. Each member of this gene family produces distinct proteins that help plants adapt to diverse stresses or stimuli by interacting with calcium ion signals. CIPK consists of two structural domains-an N-terminal domain and a C-terminal domain-connected by a junction domain. The N-terminal domain, the site of phosphorylation, is also called the activation domain and kinase domain. The C-terminal, also known as the regulatory domain of CIPK, further comprises NAF/FISL and PPI. CBL comprises four EF domains and conserved PFPF motifs and is the site of binding with the NAF/FISL domain of CIPK to form a CBL-CIPK complex. In addition, we also performed a bibliometric analysis of the CIPK gene family of data extracted from the WoSCC. A total of 95 documents were retrieved, which had been published by 47 sources. The production over time was zigzagged. The top key terms were gene, CIPK, abiotic stress, and gene expression. Beijing Forestry University was the top affiliation, while The Plant Cell was the top source. The genomics and metabolomics of this gene family require more study.
    Keywords:  CIPK; bibliometric; biotic and abiotic stresses; gene family; protein kinases; transcription regulation; web of science
    DOI:  https://doi.org/10.3389/fgene.2022.1041078
  61. Anaesthesia. 2022 Sep;77(9): 981-990
    Trends in country and gender representation on editorial boards in anaesthesia journals: a pooled cross-sectional analysis.
    Anaesthesia Journal Editorial Board Diversity and Representation Study Group
      Evidence exists that women and people from low- and middle-income countries are under-represented on the editorial boards of medical journals. This may adversely influence the journal output. We conducted a pooled, cross-sectional evaluation of the editorial board membership of anaesthesia journals. We collected data on members of editorial boards from the founding year and at 5-yearly intervals until 2020. For each editor, we recorded gender, country of affiliation, World Bank income classification (1990 onwards) and editorial role (2020 only). The composite editorial board diversity score was calculated for each editorial board. We obtained complete data for the composition of editorial boards from all 30 journals for 2020, but for only 171 out of 304 editorial boards (56%) over the time period examined. In 2020, 409 out of 1973 (21%) were women (range across the editorial boards 0-39%) and 139 out of 1982 (7%) were from low-, low-middle- and upper-middle-income countries (range across the editorial boards 0-71%). In 2020, of editorial board positions with known seniority status, 109 out of 259 (42%) of women and 306 out of 960 (32%) of men were in senior roles. In the same year, 397 out of 1115 (36%) of people from high-income countries were in senior roles, compared with 19 out of 93 (20%) of people from upper-middle-income countries and 0 out of 14 (0%) people from lower-middle-income countries. The median composite editorial board diversity score was 4 (range 2-6) in 2020 - 5 or less suggests poor diversity, while 8 or more suggests good diversity. Women and people from low- and middle-income countries are under-represented on anaesthesia journal editorial boards. The editorial boards do not reflect the anaesthesia workforce and may act as a barrier to the publication of research produced by these groups. Urgent action is required to improve diversity.
    Keywords:  LMIC; diversity; editorial board; gender; representation
    DOI:  https://doi.org/10.1111/anae.15733
  62. Medwave. 2022 Nov 29. 22(10): e2654
    An exploratory study of citations in systematic reviews of randomized trials published in Latin American journals.
    Vivienne C Bachelet, Jonathan Calabrán, Emma Krögh, Javiera Leon, Julio Villanueva.
      Introduction: The prevalence of inclusion of randomized controlled trials published in Latin American journals has not been evaluated yet. This study explores the extent to which randomized trials published in Latin American medical journals are cited and used in systematic reviews.Methods: We did a descriptive observational study on randomized trials published in MEDLINE-indexed Latin American journals from 2010 to 2015. The primary outcome was the inclusion of these trials in systematic reviews. The secondary outcome was the total number of citations each trial received, as reported by Google Scholar.
    Results: Twenty-nine journals were selected. After searching these journals, we found 135 trials that fulfilled the inclusion criteria accounting for 2% of all research articles published in these journals. Of these, 55 (41%) were included in 202 systematic reviews. Of the nine most-cited randomized trials by systematic reviews and meta-analyses, only two were published in Spanish. Nine received zero citations by any article type. Most had small sample sizes.
    Conclusions: The overall impact of randomized controlled trials published in Latin American journals is low. Little funding, language bias and small sample sizes may explain the low inclusion in systematic reviews and meta-analyses.
    Keywords:  Language bias; Latin America; Randomized controlled trials; Systematic reviews
    DOI:  https://doi.org/10.5867/medwave.2022.10.2654
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