bims-evares Biomed News
on Evaluation of research
Issue of 2022–09–25
sixty-six papers selected by
Thomas Krichel, Open Library Society



  1. Front Surg. 2022 ;9 989513
       Purpose: We aimed to comprehensively analyze the current status, hotspots, and trends in full endoscopic spine surgery (FESS) research using bibliometric analysis and knowledge domain mapping.
    Methods: The Web of Science database was used to screen FESS-related articles published between January 1, 1993 and June 10, 2022. The evaluation involved the following criteria: total number of articles; H-index; and contributions from countries/regions, institutions, journals, and authors.
    Results: A total of 1,064 articles were included. Since 2016, there have been a significant number of publications in the field of FESS. The country/region contributing the largest number of articles was China (37.8%), followed by South Korea (24%), the United States (16.1%), Japan (5.7%), and Germany (5.1%). South Korea (35) had the highest H-index, followed by the United States (27), China (22), Japan (21), and Germany (20). World Neurosurgery (15.7%) published the largest number of FESS-related articles. However, among the top 10 most cited articles, six were published in Spine. The author who contributed the most was S.H. Lee (5.4%), and the largest number of contributions in this field originated from Wooridul Spine Hospital (South Korea; 6.1%). Notably, six of the 10 most published authors in this field were from South Korea. Of the top five productive institutions, three were from South Korea. The keywords with the strongest citation bursts in the field of FESS were "lumbar spine," "discectomy," "interlaminar," "surgical technique," "follow-up," "excision," "thoracic spine," and "endoscopic surgery." The 10 clusters generated in this study were: "endoscopic discectomy" (#0), "thoracic myelopathy" (#1), "recurrent lumbar disc herniation" (#2), "low back pain" (#3), "cervical vertebrae" (#4), "lumbar spinal stenosis" (#5), "transforaminal lumbar interbody fusion" (#6), "radiation exposure" (#7), "management" (#8), and "lumbar spine" (#9).
    Conclusion: Global research on FESS is mostly concentrated in a few countries/regions and authors. South Korea has made the largest contribution to the field of FESS. Based on the most cited keyword bursts and clusters, the focus of FESS research was found to include its indications, management, and applications.
    Keywords:  bibliometric; citespace; full endoscopic spine surgery; research trends; visualization
    DOI:  https://doi.org/10.3389/fsurg.2022.989513
  2. Medicine (Baltimore). 2022 Sep 16. 101(37): e30545
       BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a common neuro developmental disorder that affects children and adolescents. It is estimated that the prevalence of ADHD is 7.2% throughout the world. There have been a number of articles published in the literature related to ADHD. However, it remains unclear which countries, journals, subject categories, and articles have the greatest influence. The purpose of this study was to display influential entities in 100 top-cited ADHD-related articles (T100ADHD) on an alluvial plot and apply alluvial to better understand the network characteristics of T100ADHD across entities.
    METHODS: Using the PubMed and Web of Science (WoS) databases, T100ADHD data since 2011 were downloaded. The dominant entities were compared using alluvial plots based on citation analysis. Based on medical subject headings (MeSH terms) and research areas extracted from PubMed and WoS, social network analysis (SNA) was performed to classify subject categories. To examine the difference in article citations among subject categories and the predictive power of MeSH terms on article citations in T100ADHD, one-way analysis of variance and regression analysis were used.
    RESULTS: The top 3 countries (the United States, the United Kingdom, and the Netherlands) accounted for 75% of T100ADHD. The most citations per article were earned by Brazil (=415.33). The overall impact factor (IF = citations per 100) of the T100ADHD series is 188.24. The most cited article was written by Polanczyk et al from Brazil, with 772 citations since 2014. The majority of the articles were published and cited in Biol Psychiatry (13%; IF = 174.15). The SNA was used to categorize 6 subject areas. On the alluvial plots, T100ADHD's network characteristics were successfully displayed. There was no difference in article citations among subject categories (F = 1.19, P = .320). The most frequently occurring MeSH terms were physiopathology, diagnosis, and epidemiology. A significant correlation was observed between MeSH terms and the number of article citations (F = 25.36; P < .001).
    CONCLUSION: Drawing the alluvial plot to display network characteristics in T100ADHD was a breakthrough. Article subject categories can be classified using MeSH terms to predict T100ADHD citations. Bibliometric analyses of 100 top-cited articles can be conducted in the future.
    DOI:  https://doi.org/10.1097/MD.0000000000030545
  3. J Oncol. 2022 ;2022 3684228
      In the pathogenesis of melanoma, NF-κB is a key signaling pathway. Appling bibliometric analysis, we identify the frontiers and hotspots about NF-κB in melanoma, as well as distinguishing features of scientific research and output all over the world during the past 22 years. 2226 publications published from 2000 to 2021 and related information were retrieved based on Science Citation Index Expanded (SCI-expanded) of Web of Science Core Collection (WoSCC). VOSviewer and Citespace were used to analyze bibliometric indicators and visualize the hotspots and research trend of studies on NF-κB in melanoma. The results indicated that despite fluctuations, the number of publications (Np) related to the research of NF-κB in melanoma per year increased over the past 22 years. The USA had the most publications. H-index and the number of citations (Nc) of the USA were also in the first place. PloS One was the most productive journal, and League of European Research Universities (LERU) was the most productive affiliation. Recently, the keywords "NF-kappa-b," "melanoma," "apoptosis," "expression," "activation," "cancer," and "metastasis" appeared most frequently. Our study suggested that articles associated with NF-κB in melanoma tend to increase. In this field, the USA was an influential country and a big producer. Most publications focused on clinical and basic research in the past 22 years, and keywords "tumor necrosis factor" and "trail induced apoptosis" had the highest burst strength.
    DOI:  https://doi.org/10.1155/2022/3684228
  4. Int J Gen Med. 2022 ;15 7277-7285
       Background: Japan created a specialty system for general medicine in 2018. However, Japanese academic generalists' contribution to research remains unclear. This study examines the popularity of Japanese general medicine research, the characteristics of journal publications, annual trends, and the characteristics/differences among publications in journals with an impact factor (IF).
    Methods: This bibliometric analysis extracted international, English-language, journal articles published on PubMed between January 1, 2015, and December 31, 2020. Analysis included articles with either the first, second, or last author in general medicine. We classified articles according to publication or article type and field of research. We obtained standard descriptive statistics for each publication type. Chi-squared test or Fisher's exact test was used to compare nominal variables. For continuous variables, t-tests or Wilcoxon rank-sum tests were used, as appropriate.
    Results: Of the 2372 articles analyzed, original articles were most common (56.3%), followed by case reports (30.1%), reviews (7.63%), and letters/others (5.9%). Publication volume increased 2.64-fold annually over 5 years. Clinical research (60.5%) was most common among original articles, followed by basic experimental research (17.5%) and public health/epidemiology (12.7%). Medical quality and safety (4.1%), medical and clinical education (3.1%), and health services (1.42%) received comparatively little attention. Eighty percent of articles were published in journals with IF; however, these journals rarely published case reports. Among original articles, the likelihood of publishing in journals with IF was high for basic laboratory medicine articles with higher IF (median IF 3.83, OR 1.71, 95% CI 2.20-5.95, p=0.044) and lower for clinical education research with the lowest IF (median IF 1.83, OR 0.56, 95% CI 01.8-0.75, p<0.001).
    Discussion: General medicine physicians' international research output is increasing in Japan; however, research achievements have not been generalized, but rather much influenced by clinical subspecialty backgrounds. This will likely continue unless an academic generalist discipline is established.
    Keywords:  academic generalist; general medicine; impact factor; research productivity; research trend
    DOI:  https://doi.org/10.2147/IJGM.S378662
  5. Front Immunol. 2022 ;13 975695
       Background: Central nervous system tumor (CNST) is one of the most complicated and lethal forms of human tumors with very limited treatment options. In recent years, growing evidence indicates that oncolytic virotherapy (OVT) has emerged as a promising therapeutic strategy for CNSTs. And a considerable amount of literature on OVT-CNSTs has been published. However, there are still no studies summarizing the global research trends and hotspots of this field through a bibliometric approach. To fulfill this knowledge gap, bibliometric analysis was conducted based on all publications relating to OVT-CNSTs since 2000s.
    Methods: We searched the Web of Science Core Collection for all relevant studies published between 2000 and 2022. Four different tools (online analysis platform, R-bibliometrix, CiteSpace and VOSviewer) were used to perform bibliometric analysis and network visualization, including annual publication output, active journals, contribution of countries, institutions, and authors, references, as well as keywords.
    Results: A total of 473 articles and reviews were included. The annual number of publications on OVT-CNSTs showed a significant increasing trend. Molecular Therapy and Cancer Research were the most active and co-cited journals, respectively. In terms of contributions, there is no doubt that the United States occupied a leading position with the most publications (n=307, 64.9%) and the highest H-index (57). The institution and author that contributed the largest number of publications were Ohio State University and Chiocca EA, respectively. As can be seen from citation analysis, the current studies mainly focused on preclinical and phase I/II clinical results of various oncolytic virus for CNSTs treatment. Keywords co-occurrence and burst analysis revealed that the following research topics including immunotherapy, T-cells, tumor microenvironment, vaccine, blood-brain-barrier, checkpoint inhibitors, macrophage, stem cell, and recurrent glioblastoma have been research frontiers of this field and also have great potential to continue to be research hotspots in the future.
    Conclusion: There has been increasing attention on oncolytic viruses for use as CNSTs therapeutics. Oncolytic immunotherapy is a topic of great concern in this field. This bibliometric study provides a comprehensive analysis of the knowledge base, research hotspots, development perspective in the field of OVT-CNSTs, which could become an essential reference for scholars in this area.
    Keywords:  bibliometric analysis; central nervous system; hotspots; immunotherapy; oncolytic virus; tumors
    DOI:  https://doi.org/10.3389/fimmu.2022.975695
  6. Front Neurol. 2022 ;13 931551
       Objective: Hemifacial spasm (HFS) is a common neurological disorder of the brain, which is difficult to treat. Most patients are distracted by it and are unable to work or study normally, which seriously affects their physical and mental health. However, there are a few bibliometric studies on it. This paper searched the articles on HFS using a bibliometric approach.
    Method: Articles about HFS were retrieved from the Web of Science (WoS) Core Collection database. We employed the Visualization of Similarities (VOS)viewer to analyze these publications.
    Results: A total of 645 reviews or articles in English were retrieved from WoS. In this study, we found that the number of publications showed a rising trend and China is the most active in searching the treatment of HFS. About keywords, neurosciences and neurology was searched (422 times) keyword, followed by hemifacial spasm (420 times) and surgery (320 times). By assessing the organizations, Shanghai Jiao Tong University published the most papers (8.68%), followed by Sungkyunkwan University (3.26%) and Baylor College Medicine (2.64%). A total of 247 journals have delivered publications on the treatment of HFS, World Neurosurgery (44 papers) published the largest number of articles.
    Conclusion: The annual publications have increased with a fluctuating tendency. More researchers were taking an interest in HFS. This study helped us find out the hotspot and trend in research about facial spasm treatment.
    Keywords:  VOSviewer; WoS database; bibliometric analysis; hemifacial spasm; treatment
    DOI:  https://doi.org/10.3389/fneur.2022.931551
  7. Front Neurol. 2022 ;13 980096
       Background: Tension-type headache (TTH) is the most prevalent headache in the clinical practice, leading to impaired social activities, work-related disability, and heavy financial burdens. Previous studies have described possible inducement, potential pathophysiology, and clinical management of TTH; however, due to the lack of attention, literature involving bibliometric analysis is sporadic. Therefore, this study aimed to explore the current hotspots and future directions of the TTH field by bibliometric analysis.
    Methods: By using CiteSpace and VOSviewer, literature regarding TTH between 2002 and 2021 from the Web of Science database was summarized and extracted. Annual publication trend, the most productive countries/regions and institutions, distribution of categories, co-citation of journals and references, and co-occurrence of keywords were analyzed.
    Results: A total of 3,379 publications were included in the final visualization, indicating a stable trend in current research and a lack of breakthroughs over the past decades. These studies were mainly conducted in 120 countries/regions led by the United States and more than 600 institutions. Four eternal core themes were identified in TTH, including neurosciences, nursing, developmental psychology, and general/internal medicine. Cephalalgia ranked first, with the highest number of literature, and is the most influential journal in this area. Keyword analysis demonstrated that the similarities and differences between migraine and TTH, epidemiological studies, clinical double-blind trials, and potential populations have become key issues in the TTH field.
    Conclusion: TTH has received less attention and breakthroughs in the past 20 years. To promote coordinated development between regions to fight headaches, cooperation and exchanges between countries and institutions are essential in the future. Relevant studies about headaches in children and adolescents, inducing factors such as emotional triggers and sleep disorders, concomitant diseases, possible pathogenesis, and headache treatments, are in the spotlight in recent years. This study offers a powerful roadmap for further research in this field.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; network; tension-type headache
    DOI:  https://doi.org/10.3389/fneur.2022.980096
  8. Int J Environ Res Public Health. 2022 Sep 15. pii: 11597. [Epub ahead of print]19(18):
      Cancer has become a major threat to global health care. With the development of computer science, artificial intelligence (AI) has been widely applied in histopathological images (HI) analysis. This study analyzed the publications of AI in HI from 2001 to 2021 by bibliometrics, exploring the research status and the potential popular directions in the future. A total of 2844 publications from the Web of Science Core Collection were included in the bibliometric analysis. The country/region, institution, author, journal, keyword, and references were analyzed by using VOSviewer and CiteSpace. The results showed that the number of publications has grown rapidly in the last five years. The USA is the most productive and influential country with 937 publications and 23,010 citations, and most of the authors and institutions with higher numbers of publications and citations are from the USA. Keyword analysis showed that breast cancer, prostate cancer, colorectal cancer, and lung cancer are the tumor types of greatest concern. Co-citation analysis showed that classification and nucleus segmentation are the main research directions of AI-based HI studies. Transfer learning and self-supervised learning in HI is on the rise. This study performed the first bibliometric analysis of AI in HI from multiple indicators, providing insights for researchers to identify key cancer types and understand the research trends of AI application in HI.
    Keywords:  CiteSpace; VOSviewer; artificial intelligence; bibliometrics; histopathological images
    DOI:  https://doi.org/10.3390/ijerph191811597
  9. Ann Med Surg (Lond). 2022 Sep;81 104330
       Background: Schizophrenia research has significantly grown in the past years. However, there is no comprehensive evaluation of schizophrenia research publications from Southeast Asia (SEA). Thus, this study determined the characteristics and trends of published articles about schizophrenia in SEA through a bibliometric analysis.
    Methods: A database search on schizophrenia research in SEA countries was performed using the Scopus databases from 1973 to 2021. Bibliometric information was obtained from Scopus, and network visualization was conducted using VOSviewer software.
    Results: There were 1068 articles on schizophrenia from SEA from 1973 until 2021. Schizophrenia research outputs from SEA started to increase from 2000 onwards. Singapore, Malaysia, and Thailand were the most productive countries in schizophrenia research and had the most collaborations. Most schizophrenia research in SEA was published in Asia- or SEA-based journals. The research hotspots for schizophrenia in SEA included treatment, pathophysiology, symptomatology, and psychological and social aspects of schizophrenia. Lastly, correlation analysis showed that gross domestic product per capita, research and development (R&D) expenditures, number of researchers in R&D, number of physicians, and international research collaborations were significantly correlated with higher research productivity and scientific impact in schizophrenia research.
    Conclusion: In conclusion, this study showed the trends and gaps for research in SEA and the socioeconomic factors correlated with research productivity for schizophrenia in SEA. This study emphasized increasing financial support and collaborations for schizophrenia research to improve research productivity in schizophrenia in the SEA region.
    Keywords:  ASEAN; Citation analysis; Mental health; Psychiatry; Scientometrics
    DOI:  https://doi.org/10.1016/j.amsu.2022.104330
  10. Front Surg. 2022 ;9 1000360
       Study Design: Bibliometric analysis.
    Objective: Anterior cervical discectomy and fusion (ACDF) is a typical surgical method in spine surgery and has progressed significantly in the last several decades. The purpose of this study is to determine how the 100 most-cited original articles on ACDF have been the most influential in this field by identifying and analyzing them.
    Methods: The articles on ACDF were identified by searching the Thomson ISI Web of Science database on 30 May 2022. The 100 most-cited articles were selected according to specific criteria. The data extracted from the articles included title, publication date, total citations, journal name, first author, institutions, and keywords.
    Results: The total number of citations was 13,181, with a mean number of 131.81 ± 100.18. The publication dates ranged from 1994 to 2018. Most of these articles originated in the United States (68%) and were published in the 2000s (32%) and 2010s (48%). Spine published most of the articles (30%), followed by the Journal of Neurosurgery-Spine (16%), Spine Journal (14%), and European Spine Journal (13%). The most prolific author was Dr. Todd J Albert (n = 7), with 1,312 citations. The Texas Back Institute was the most productive institution (n = 10). The keywords ACDF, cervical spine, cervical spine, and fusion showed the highest degree of centrality.
    Conclusion: One hundred top-cited articles on ACDF were identified and analyzed in this study. We demonstrate that ACDF is a growing and popular area of research, with the focus of research varying through timeline trends. This will provide a comprehensive and detailed basis for spine surgeons to make clinical decisions and assimilate the research focus of cervical spine surgery.
    Keywords:  ACDF; anterior cervical discectomy and fusion; bibliometric analysis; most cited articles; top 100
    DOI:  https://doi.org/10.3389/fsurg.2022.1000360
  11. Medicine (Baltimore). 2022 Sep 16. 101(37): e30357
       BACKGROUND: To analyze global trends in focus and funding of research related to high tibial osteotomy (HTO) and to identify the 100 most cited articles in this field.
    METHODS: A Web of Science search was used to identify HTO publications in English-language scientific journals from January 1967 till February 3th, 2021. Results were filtered to the 100 most cited articles by reading the abstract or full-text paper. Information of these articles was recorded for further analysis. The 10 top-cited articles during the last 5 years and the 10 top-cited articles about HTO ranked by average citations per year were selected to predict research trends.
    RESULTS: In all, 48 out of the 100 top-cited articles were published between 2000 and 2010. The United States of America was the primary contributor (n = 29) followed by Germany (n = 17) and Japan (n = 11). The total number of citations per article ranged from 65 to 563, median 108, mean 135 (standard deviation = 84). The American Journal of Bone and Joint Surgery accounted for 23 out of the 100 top-cited articles. Koshino T was the most cited author (603 citations). The most frequently highlighted study theme was prognostic research. Patient-based clinical research was the dominant study design (85%). The majority of articles (48 out of 100) were level IV evidence with a mean of 141 (standard deviation = 97) citations. Top-cited articles in the last 5 years focused on open wedge osteotomy.
    CONCLUSION: Technical optimization of open wedge osteotomy has emerged as the main area of research in HTO. More specifically, recent publications focus on the surgical technology, cartilage repair and new fixation devices. Besides, papers with a high level of evidence are needed for the development of HTO.
    DOI:  https://doi.org/10.1097/MD.0000000000030357
  12. Childs Nerv Syst. 2022 Sep 23.
       BACKGROUND: Since the advent of endovascular treatment, the long-term prognosis of vein of Galen malformation (VOGM) has markedly improved; however, the nature of research leading to this point is unclear. The objective of this study was to define the composition of VOGM research to date, by means of a bibliometric analysis of the 100 most cited VOGM articles.
    METHODS: An electronic search of Elsevier's Scopus database was performed to identify the 100 most cited articles on VOGM screened against predetermined criteria. Data were then compared.
    RESULTS: The 100 most cited VOGM articles were published between 1974 and 2017 in 38 unique journals and originated from 16 unique countries. Mean citation count and rate were 59.4 citations and 2.9 citations/year, respectively. The USA (n = 42); Hôpital de Bicêtre, France (n = 15); and Dr. Pierre Lasjaunias (n = 16) were the largest individual country, institutional, and author contributors. Compared to the older articles (published < 2000), key differences for newer articles were statistically higher citation rates (P < 0.01), more authors (P < 0.01), higher proportion of endovascular treatment descriptions (P = 0.01), and more originating from Asia Pacific (P < 0.01).
    CONCLUSIONS: From the 100 most cited VOGM articles to date, there has been a noticeable shift from diagnosing VOGM based on the foundational work by Dr. Lasjaunias to understanding how we can model clinical outcomes now that endovascular treatment has become the standard of care. Significant shifts in prognosis are pending, and the current bibliometric data implicate we are on the precipice of more recent works making an impact in the near future.
    Keywords:  Bibliometric; Congenital vascular lesions; Most cited; Trends; VOGM; Vein of Galen malformation
    DOI:  https://doi.org/10.1007/s00381-022-05687-1
  13. J Optom. 2022 Sep 20. pii: S1888-4296(22)00040-1. [Epub ahead of print]
       PURPOSE: The objective of this study is to analyse co-authorship and co-citation networks of publications in the field of artificial intelligence in ophthalmology and optometry. As well as, identify the different areas of research and the most cited publication.
    METHOD: A search of publications was performed in the Web of Science database for the period from 1977 to December 2021, using the term "Artificial Intelligence AND (Ophthalmol* OR optometry)". The analysis of the publication was carried out using the Citation Network Explorer, VOSviewer and CiteSpace software.
    RESULTS: 1086 publications and 2348 citation networks were found. 2020 was the year with the highest number of publications, a total of 351 publications and 115 citation networks. The most cited publication was "Clinically applicable deep learning for diagnosis and referral in retinal disease" published by De Fauw et al. in 2018, with a citation index of 723. Through the clustering function, three groups were found that cover the main research areas in this field: retinal pathology, anterior segment and glaucoma.
    CONCLUSIONS: The citation network analysis offers an in-depth analysis of scientific publications and the adoption of new topics and fields of research. The results of an exhaustive analysis of citation networks in artificial intelligence in the field of ophthalmology and optometry are presented since the publication of the first article in 1977.
    Keywords:  Artificial intelligence; Citation network; Vision
    DOI:  https://doi.org/10.1016/j.optom.2022.06.005
  14. Front Public Health. 2022 ;10 979861
       Objectives: Drug-induced gingival overgrowth (DIGO) is a frequent adverse medication reaction that is generally caused by cyclosporine, phenytoin, and nifedipine, which belong to the category of immunosuppressants, anticonvulsants, and calcium channel blockers, respectively. This bibliometric analysis aims to depict the main citation characteristics and analyze the research trends in DIGO investigations.
    Methods: An exhaustive search was performed in the Scopus database to create the bibliometric list of DIGO in the syntax. Furthermore, the information related to the number of citations, drugs related to DIGO, study topic and design, authorship, publication year, journal, contributing institution, country of origin, and the department was extracted.
    Results: In total, 399 papers on DIGO were retrieved in this study. The total number of citations and that after the removal of self-citations were 7,814 and 7,314, respectively. The mean number of citations was 19.6 in a range of 0-608. The main paper types were articles (76.94%) and reviews (19.55%). A remarkable increasing trend in the number of citations has been observed since 1994. Cyclosporine (44.89%) is the most commonly used drug that shares a close relationship with DIGO, followed by phenytoin (18.22%), nifedipine (17.93%), and amlodipine (6.81%). The review (27.82%) type constituted the most widely used design in the DIGO studies. According to the top 20 keywords, the risk factors and pathogenesis of DIGO have been prominent topics of research works for several years.
    Conclusions: This bibliometric analysis will facilitate the understanding of researchers and clinicians, especially those at the beginning of their careers in periodontology on DIGO, by identifying landmark research and providing an overview of this field.
    Keywords:  Scopus; bibliometric; citation analysis; drug-induced gingival overgrowth; research trends
    DOI:  https://doi.org/10.3389/fpubh.2022.979861
  15. Clin Rheumatol. 2022 Sep 19.
      This study aimed to perform a bibliometric analysis of the IgG4-related disease (IgG4-RD) research field over the past 20 years to explore its research hotspots and trends. The literature of IgG4-RD published in the Web of Science Core Collection databases was reviewed from January 1, 2003, to April 30, 2022. A bibliometric analysis was carried out using CiteSpace software to evaluate and visualize the evolving dynamics and hotspots in the field of IgG4-RD. A total of 3174 IgG4-RD articles were reviewed. Since 2011, there has been a rapid increase in published literature. Japan is the highest yielding country and Kanazawa University the highest yielding institution. The USA has the highest centrality (0.34) and plays a critical role in cooperation and communication of IgG4-RD research. Nine highly connected clusters of IgG4-RD were observed by keyword analysis. Research hotspots included IgG4-RD involved organs and differentiation from Rosai-Dorfman disease and primary sclerosing cholangitis. Further research topics include pathogenesis, relapse, and malignancy. As a cross-discipline systemic disease, IgG4-RD requires attention by clinicians in multiple fields. This bibliometric analysis can help researchers grasp trends and provide new perspectives for future research on IgG4-RD.
    Keywords:  Bibliometric analysis; CiteSpace; IgG4-RD; Research hotspots; Web of Science Core Collection Databases
    DOI:  https://doi.org/10.1007/s10067-022-06377-8
  16. BMJ Open. 2022 Sep 20. 12(9): e063365
       OBJECTIVES: To describe and map scientific literature related to alcohol consumption, its determinants, governance, harm and control policies by publication output, author affiliations, funding, countries of study and research themes.
    DESIGN: Bibliometric analysis using performance analysis and science mapping techniques.
    DATA SOURCES: Scientific articles.
    ELIGIBILITY CRITERIA: Indexed scientific articles published between 1 January 2010 and 31 December 2021 with an English abstract focused on alcohol consumption, its determinants, harms, governance and control policies.
    DATA EXTRACTION AND SYNTHESIS: Searches were run in Web of Science and PubMed. Performance metrics were analysed using descriptive statistics. Keywords were used for science mapping in a deductive approach to cluster articles by five main research themes. The 'policy response' theme was further analysed by six subthemes.
    RESULTS: 4553 articles were included in the analysis. Three out of four articles (3479/4553, 76.4%) were authored solely by authors affiliated with HIC institutions. One in five articles (906/4553, 19.9%) had at least one author affiliated to an institution from an upper-middle-income, middle-income or low-income country context. Governments, followed by research institutions, were the predominant funding source. Half (53.1%) studied a single country and, of these, 77.0% were high-income countries (HICs). Australia, USA and UK were the most studied countries, together accounting for 44.9% (975/2172) of country-specific articles. Thematically, 'consumption' was most studied, and 'alcohol determinants', least. 'Policy response' articles were predominately conducted in HIC contexts.
    CONCLUSIONS: Although the attributable harm of alcohol is known to affect more significantly lower-income and middle-income countries, scientific publications primarily report on HIC contexts by authors from HICs. Research themes reflect known cost-effective policy actions, though skewed towards HICs and a focus on consumption. The implementation of context-specific alcohol control policies requires addressing the determinants of the uneven geographical and thematic distribution of research.
    Keywords:  Health policy; alcohol; health promotion; quantitative research; risk factor
    DOI:  https://doi.org/10.1136/bmjopen-2022-063365
  17. J Psycholinguist Res. 2022 Sep 20.
      This study adopted descriptive and explorative methods to analyze 2162 published documents, in general, and 1903 articles, in particular, in System from 1973 to 2020 based on the Scopus database. Data preprocessing and analysis were performed using data mining, text mining, and bibliometric techniques through Excel, VOSviewer, and RapidMiner software. To analyze the article titles and identify their themes, N-Grams was considered among the text mining techniques. From the data mining techniques, clustering was applied to explore the clusters of languages, educational technologies, technological spaces for foreign languages, etc. Bibliometric techniques such as co-authorship networks and citation analysis were in turn used to analyze the tops and trends of research in System. The results are classified into 5 categories including: (1) journal status; (2) publication trend; (3) articles with and without abstract/keyword; (4) highly-cited and uncited articles; (5) core and poor topics and keywords. The core topics are English as a Foreign Language, motivation, and second language acquisition. Among the languages, English, Chinese, and Japanese are at the top, and Italian, Danish, Persian, and Taiwanese are less discussed. Based on the findings, System has moved in line with its goals and scope, which are the applications of educational technology and applied linguistics to solve the problems of foreign language teaching and learning.
    Keywords:  Applied linguistics; Bibliometric analysis; Data mining analysis; Language and linguistics; Psycholinguistics; Research trends; Text mining analysis
    DOI:  https://doi.org/10.1007/s10936-022-09911-6
  18. Front Pharmacol. 2022 ;13 973118
      This study aimed to analyze the landscape of maternal methylmercury exposure and its offspring consequences based on knowledge mapping of the 100 most-cited papers about this theme. A search was performed using the Web of Science, without any restriction of language or publication year. Data bibliometrics, such as the number of citations, citation density, corresponding author's country, year of publication, study design, and keywords, were extracted from each paper and analyzed. VOSviewer software was used to create graphical bibliometric maps. Of a total of 1,776 studies on this theme, the 100 most-cited papers rendered the number of citations ranged from 110 to 1,356 citations. The non-systematic reviews and cohort studies from Anglo-Saxon countries published in the first decade of the 2000s were the most frequent. Clarkson, Grandjean, and Myers were the authors with higher citation density. A total of 520 keywords represented the evolution of the theme, from classic episodes of MeHg intoxication, as well as main the health changes until the different forms of exposure and, in recent years, biomonitoring studies were highlighted. Our findings provide the global research trends highlighting the network of most influential authors and a better understanding of the evolution and future scenarios of this theme.
    Keywords:  bibliometrics; methylmercury; neonatal outcomes; pregnancy; toxicology
    DOI:  https://doi.org/10.3389/fphar.2022.973118
  19. Medicine (Baltimore). 2022 Sep 16. 101(37): e30413
       BACKGROUND: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease, which is well known for its poor symptoms, and the incidence is increasing worldwide. Although conventional medicines are practiced initially, patients often move or accompany to complementary and alternative medicines for better outcomes. Herbal medications, one of traditional medicinal approach, are widely used in clinical conditions. However, no research has broadly reviewed the current research trends regarding the scope of herbal medicines in RA. The aim of this study was to conduct a bibliometric analysis of applications of herbal medicine for RA from 1991 to the present.
    METHODS: We retrieved literature on herbal medicine for RA from the Web of Science database from 1991 to 2021. The VOSviewer program was used to analyze keywords, authors, countries, and organizations through visual knowledge mapping to assess the research hotspots and trends.
    RESULTS: A total of 516 articles were included in the analysis, which showed an increasing trend in the number of publications over time. Four clusters were identified from the keyword analysis: complementary and alternative medicine cluster, mechanism of the pain cluster, control for the pain cluster, and recent research trend cluster. People's Republic of China published 250 articles, which was the greatest number of publications, followed by the United States of America (82 articles) and South Korea (52 articles). Furthermore, Moudgil, KD of the University of Maryland published 15 articles about the mechanism of herbal medicine on autoimmune arthritis and their interaction with various drugs. Lu, AP of the Hong Kong Baptist University published 14 articles about herbal medicine interactions. On an institutional level, the China Academy of Chinese Medical Science published 33 articles, followed by the Hong Kong Baptist University and the University of Maryland with 27 and 20 articles, respectively. Clusters of organizations from the People's Republic of China and the United States of America revealed higher average citations for earlier average publication years.
    CONCLUSIONS: This bibliometric study identified trends in herbal medicine for RA from 1991 to 2021, which may guide the hot topics and future directions in this research field.
    DOI:  https://doi.org/10.1097/MD.0000000000030413
  20. Circulation. 2022 Sep 22. 101161CIR0000000000001094
    American Heart Association Research Committee
      A task force composed of American Heart Association (AHA) Research Committee members established processes to measure the performance of the AHA's research portfolio and evaluated key outcomes that are fundamental to the overall success of the program. This report reviews progress that the AHA research program has had in achieving its goals relevant to the research programs in the AHA's research portfolio from 2008 to 2017. Comprehensive performance metrics were identified to assess the impact of AHA funding on researchers' career progress and research outcomes. Metrics included bibliometric analysis (ie, tracking of publications and their impact) and career development measures (ie, subsequent grant funding, intellectual property, faculty appointment/promotion, or industry position). Publication rates ranged from ≈0.5 to 4 publications per year, with a strong correlation between number of publications per year and later career stage. The Field-Weighted Citation Index, a metric of bibliometric impact, was between 1.5 and 3.0 for all programs, indicating that AHA awardee publications had a higher citation impact compared with similar publications. To gain insight into the career progression of AHA awardees, a 2-year postaward survey was distributed. Of the Postdoctoral Fellowship recipient respondents, 72% obtained academic research positions, with the remaining working in industry or government research settings; 72% of those in academic positions obtained additional funding. Among respondents who were Beginning Grant-in-Aid and Scientist Development Grant awardees, 45% received academic promotions and 83% obtained additional funding. Measuring performance of the AHA's research portfolio is critical to ensure that its strategic goals are met and to show the AHA's commitment to high-quality, impactful research.
    Keywords:  AHA Scientific Statements; cardiovascular diseases; research report
    DOI:  https://doi.org/10.1161/CIR.0000000000001094
  21. Front Psychiatry. 2022 ;13 931575
       Objective: A bibliometric analysis of COVID-19 is conducted to examine the developmental context, research hotspots, and frontiers of mental health.
    Methods: Using the Web of Science Core Collection (WOSCC), we have retrieved articles on mental health research related to COVID-19 which were published between 2019 and 2021. The coauthorship of countries, institutes, and authors was analyzed using VOSviewer 1.6.17, and the co-citation map of authors/references was analyzed as well. CiteSpace version 5.8.R3 was used to analyze keyword clusters and forecast research frontiers.
    Results: There were 8,856 articles retrieved, including 10,559 research institutes and 1,407 academic journals. The most published country and institutes were the United States (2190) and the University of London (373). Wang, Chengyu owned the highest co-citations (1810). Frontier topics can be identified by trending keywords, including "anxiety," "depression," "psychological distress," "quarantine," "post-traumatic stress disorder (PTSD)," "insomnia," and "Healthcare workers."
    Conclusion: The most common psychological problems of people during the epidemic are anxiety and depression. Insomnia and PTSD need to be solved under the normalization of the epidemic. GAD-7 and PHQ-9 scales are the most convenient and effective for screening anxiety and depression. Healthcare workers, older adults, and college students should be concerned, and social and family support is essential.
    Keywords:  COVID-19; CiteSpace; VOSviewer; mental health; scientometric analysis
    DOI:  https://doi.org/10.3389/fpsyt.2022.931575
  22. Front Cardiovasc Med. 2022 ;9 920491
       Background: With high morbidity and mortality, cardiopathy is a major component of cardiovascular disease, causing a huge burden of disease to public health worldwide. In recent years, research on acupuncture treatment of cardiopathies has been increasing. However, no bibliometric analysis has been conducted to systematically describe the research progress and hotspots in this field. Therefore, this study aimed to conduct a bibliometric analysis of the relevant literature to explore the current status and future development of acupuncture for cardiopathies.
    Methods: The Web of Science (WoS) Core Collection Database was searched for literature related to acupuncture therapies for cardiopathies from 2011 to 2021. Using CiteSpace 5.8 R3, cooperation network diagrams of authors, institutions, countries and journals, keyword co-occurrences, and clustering were performed and analyzed.
    Results: A total of 321 studies were included. Overall, the number of annual publications increased yearly. These publications came from 31 countries or regions, of which China and the United States made the greatest contributions. In total, 333 authors from 258 institutions participated in this field, and Beijing University of Chinese Medicine and Professor Fanrong Liang were the most published institution and author, respectively. Evidence-based Complementary and Alternative Medicine published the largest number of articles, and CIRCULATION was the most commonly cited journal. Based on co-occurrences and cluster analysis of 257 keywords, three research frontiers and hotspots were identified: acupuncture for blood pressure regulation, acupuncture for coronary heart disease, and acupuncture for regulation of heart rate. In these three research frontiers, the rostral ventrolateral medulla (RVLM) and autonomic nervous system (ANS) are the most popular mechanisms.
    Conclusion: A stable development trend has formed in this field. Further research should focus on the role of acupuncture therapies in the treatment of hypertension or hypertensive heart disease, coronary heart disease, and arrhythmia based on the mechanisms related to the RVLM and ANS.
    Keywords:  CiteSpace; acupuncture; bibliometric analysis; cardiopathy; cardiovascular disease
    DOI:  https://doi.org/10.3389/fcvm.2022.920491
  23. Int J Environ Res Public Health. 2022 Sep 17. pii: 11728. [Epub ahead of print]19(18):
      This study aims to map the knowledge structure and themes trends of primary ovarian insufficiency (POI) therapy to help researchers rapidly master the hotspots and prospects of POI therapy from the increasing number of publications. The literature search and bibliometric analyses were performed by using Web of Science Core Collection and VOSviewer. Annual publications from 2000 to 2022 continued to increase with some fluctuations. The most productive country, organization, and journal were the USA, Shanghai Jiao Tong University, and Human Reproduction, respectively. Harvard University was the organization with the highest citation. Fertility and Sterility and Nelson, L.M. were the most influential journal and author, respectively. Seven clusters separated by keywords association showed the extensive scope of POI therapy. The hotspots of POI therapy were hormone replacement therapy and fertility preservation, and the innovative treatment strategies including in vitro activation and mesenchymal stem cells had development potential. In addition, our result showed that the high-cited articles were published in journals with high impact factors. The paper provides a comprehensive overview of the development and hotspots of POI therapy, allowing researchers to recognize the current status and future directions of POI therapy.
    Keywords:  bibliometric analysis; primary ovarian insufficiency; science mapping; therapy
    DOI:  https://doi.org/10.3390/ijerph191811728
  24. Front Pharmacol. 2022 ;13 1007491
      Background Research on drug therapy for HIV remained major hot-spots, but relevant data were not satisfactory. We aimed to assess the status and trends of the most cited studies on drug therapy for HIV by using bibliometric methods. Methods The Web of Science Core Collection database was searched for the drug therapy for HIV studies. The period for retrieval was from the beginning of the database to July 26, 2022. The 100 top cited studies were selected. These general information and bibliometric data were collected and analyzed. VOS viewer software was used for visualization analysis. Results The number of citations for the 100 top cited studies ranged from 451 to 5597 and were published from 1987 to 2017. These studies were published in 29 journals. The top 3 journals in terms of the number of studies were the New England Journal of Medicine (n = 22), Lancet (n = 15), and JAMA (n = 13). The most frequently nominated author was Matthias Eiger from the University of Bern, who has contributed 5 studies. United States, Switzerland, and England contributed most of the highly cited studies. Research hot spots reflected clinical trials, treatment adverse events, basic research, and clinical adherence. Conclusion The majority of 100 top-cited studies have been published in the United States, and primarily focused on treatment adverse events, basic research, and clinical adherence. They provide a basic list of the most important and influential academic contributions to literature of HIV drug treatment for researchers.
    Keywords:  HIV; citation analysis; drug therapy; hotspots; top-cited
    DOI:  https://doi.org/10.3389/fphar.2022.1007491
  25. Animals (Basel). 2022 Sep 07. pii: 2321. [Epub ahead of print]12(18):
      An increasing number of scientists since 1970 has examined Artemia as an important species in aquaculture-related fields. However, a global scientometric review of Artemia literature is still lacking, which is the objective of this research. Using a CiteSpace analysis, the distribution of core authors and institutions, highly cited keywords and papers, author and journal contributions, and hot topics in the literature, as well as a co-citation analysis, particularly regarding authors, journals, documents, and clusters, were determined. Hence, 8741 relevant publications were generated from the Web of Science Core Collection database. The results revealed that the most significant contributions in Artemia research primarily originated from the USA, Brazil, Spain, India, China, and Belgium. Moreover, Artemia research focused mainly on top keywords such as brine shrimp and antimicrobial activity. Emerging trends related to Artemia research were Atlantic halibut, elongation factor, Artemia salina, lean protein, inert diet, alpha-crystallin protein, and Artemia embryo. At the same time, the study generated a vast total of 45 co-citation clusters. The present study provides the existing body of knowledge on Artemia research by sharing a visual knowledge map. This study offers a valuable perspective and profound understanding for researchers, farmers, and consortia interested in promoting Artemia as a sustainable live food in the global aquaculture industry.
    Keywords:  crustacea; decapoda; fish; larval rearing; shrimp
    DOI:  https://doi.org/10.3390/ani12182321
  26. Int J Environ Res Public Health. 2022 Sep 06. pii: 11176. [Epub ahead of print]19(18):
      The growing emphasis on evidence-based practice has led to a need for more research on healthcare disciplines, and for the synthesis and translation of that research into practice. This study explored the global research trend in regard to End-of-Life Care (EoLC), and assessed the impact and influence, on the scientific community, of relevant EoLC publications EoLC. Over 350,000 related publications on EoLC were retrieved from three databases (PubMed, Scopus, and Web of Science). Our analysis of the global research trend revealed an exponential rise in the number of related publications on EoLC since the year 1837. This study assessed the bibliometric information of 547 current journal publications on EoLC, sorted by relevance, from the three databases. The USA (47.3%) and the UK (16.1%) were the most productive countries, in terms of the number of relevant publications. The bibliometric analysis also revealed which EoLC research was most impactful and influential, from different parameters including documents, authors, sources, and organisations. The keyword analysis further suggested the growing importance of advance care planning and decision-making in regard to EoLC, as well as an episodic upsurge of EoLC publications related to the COVID-19 pandemic. There were few collaborations among the prolific research on EoLC. This study recommends increased research collaboration across the globe, for wider wisdom-sharing on EoLC issues.
    Keywords:  End-of-Life Care; advance care; bibliometric analysis; palliative care; research trend; terminal care
    DOI:  https://doi.org/10.3390/ijerph191811176
  27. Medicina (Kaunas). 2022 Aug 29. pii: 1170. [Epub ahead of print]58(9):
      Background and Objectives: Fracture-related infection (FRI) is a challenging complication in trauma surgery. A consensus definition of FRI has only recently been published. Therefore, the purpose of this study was to evaluate the state of research related to FRI. Material and Methods: A systemic literature review was conducted on research on FRI published between 2017 and 2020. The Web of Science database was used, and a bibliometric analysis was performed. To provide robust evidence regarding the impact of publications, the behavior of publications in non-traditional dissemination channels was analyzed. For this, the Research Interest Score and the Altmetric Score were combined. The Research Interest Score was calculated from information extracted from ResearchGate, while Altmetric Score includes information from different websites and apps with a significant volume of traffic, such as Twitter. Results: A total of 131 published papers were identified. The most significant contribution came from the United States and European countries. The most relevant articles were published by the journal Injury-International Journal of the Care of the Injured. A positive correlation was observed between the number of citations and Research Interest Scores, whereas the number of citations and Altmetric Score showed no correlation. The social media platform most used by FRI researchers was Twitter. Conclusions: By evaluating the status of publications for FRI between 2017 and 2020, an upward trend in the number of publications was evident. This could be related to the increasing acceptance of the long-needed definition for FRI and the implications it carries for daily clinical practice.
    Keywords:  bibliometry; fracture-related infection; medical information science; research scores
    DOI:  https://doi.org/10.3390/medicina58091170
  28. J Am Pharm Assoc (2003). 2022 Aug 23. pii: S1544-3191(22)00288-6. [Epub ahead of print]
       BACKGROUND: There are approximately 352,000 pharmacists practicing in the United States, with most (59%) being female. Editorial board membership and publications with a female as the first author in selected pharmacy journals has increased in the past 2 decades. This study determined whether these positive trends are also occurring in critical care pharmacy.
    OBJECTIVE: To report publication rate and publication impact stratified by male and female gender among pharmacists designated Fellow of Critical Care Medicine (FCCM).
    METHODS: Pharmacists designated FCCM from inception through the 2020 convocation year were identified in January 2021 using a list provided by the Society of Critical Care Medicine. Pharmacists were excluded if they were designated Master of Critical Care Medicine, did not have an active pharmacist license, or did not have data in the Scopus database. Data were collected in February 2021 including year of first publication, total number of publications, citations, and Hirsch index (h-index).
    RESULTS: A total of 134 pharmacists were evaluable, including 76 males (57%) and 58 females (43%). Males had an earlier first publication year than females (2005 vs. 2010; P < 0.001). Males have produced a higher number of publications per individual pharmacist (29 vs. 13; P = 0.002) and a similar number of publications per year (2 vs. 1; P = 0.05). When comparing publication impact, males generated more citations (384 vs. 139; P = 0.001) and had a higher h-index (10 vs. 6, P < 0.001). These trends persisted when data from only the past 5 years were used.
    CONCLUSION: There is statistically significant gender disparity in publication rate and impact. However, this disparity seems to be decreasing with time as the rate of females designated FCCM is increasing. This is consistent with an overall increase in the proportion of pharmacists who are female and deserves further exploration.
    DOI:  https://doi.org/10.1016/j.japh.2022.08.018
  29. Medicine (Baltimore). 2022 Sep 16. 101(37): e30714
       BACKGROUND: Radiation enteritis (RE) caused by radiation therapy, can seriously affect human health. Recently, studies on RE have been growing rapidly, but there are no bibliometric studies on RE. This study aims to explore the development trends and research hotspots of RE.
    METHODS: Academic papers on the Web of Science were retrieved on the topic of "radioactive enteritis" from the establishment of the database to December 2020. Countries, institutions, and subjects selected in this field were visualized using Citespace, HistCite, and Vosviewer. The annual trends in publications, distribution, co-authorship status, and research hotspots were analyzed.
    RESULTS: The authors ranked first in terms of publication amount were Delaney, Francois, Milliat, and Vozenin-Brotons. The United States had the highest number of posts, followed by China, France, the United Kingdom, and Spain.
    CONCLUSION: Future research in the field of RE will focus on double-blind clinical trials of RE, and the related mechanisms, such as oxidative stress and apoptosis.
    DOI:  https://doi.org/10.1097/MD.0000000000030714
  30. J Knee Surg. 2022 Sep 19.
       BACKGROUND: Concentrated bone marrow aspirate (cBMA) has garnered widespread and increasing attention in recent years. We aimed to characterize the most influential articles in cBMA research while clarifying controversies surrounding its use and clinical efficacy and identifying important areas on which to focus future research efforts.
    METHODS: The Science Citation Index Expanded subsection of the Web of Science Core Collection was systematically searched to identify the top 50 most cited publications on orthopedic cBMA research. Publication and study characteristics were extracted, and Spearman correlations were calculated to assess the relationship between citation data and level of evidence.
    RESULTS: The top 50 articles were published between the years 1996 and 2018, with 58% published in the year 2010 or later. Of the 29 studies for which level of evidence was assessed, the majority were Level IV (24, 83%). Twenty-one articles (42%) were classified as basic science or translational (9 cell culture, 8 animal study, and 4 using human blood samples). Application to treat cartilage defects was the most common focus of studies (17 studies, 34%), followed by analysis of cBMA composition (14 studies, 28%). No correlation was found between rank, citation rate, or year of publication and level of evidence.
    CONCLUSIONS: The most influential articles on cBMA are recent and consist of a majority low-level of evidence studies. Cohort studies were the most common study type among the top 50 most cited articles, while basic science articles were relatively less common. These results suggest a rapidly evolving field with the potential to better explain inconsistent clinical results with improved understanding and documentation of basic science concepts in addition to large-scale, prospective clinical trials. Orthobiologics and especially cBMA holds great promise for the future, and higher-level clinical trials will help better define the best clinical uses for this treatment.
    DOI:  https://doi.org/10.1055/a-1946-6981
  31. Clin Radiol. 2022 Sep 21. pii: S0009-9260(22)00335-X. [Epub ahead of print]
       AIM: To identify the most disruptive publications, which are those that are cited more frequently than their own references, in academic radiology journals and their characteristics, such as the number of authors and relative time to publication.
    MATERIAL AND METHODS: A comprehensive literature search was undertaken to identify the 100 most disruptive publications in the field of radiology. Subsequently, statistical analysis was applied to establish the distribution of disruptive scores of the isolated publications using a non-parametric probability density function. The relation between disruptive scores and citation counts was then determined, with the aid of a correlation coefficient. Finally, data regarding any significant connection between disruption scores and time of publication, number of authors, and study design were examined.
    RESULTS: Analysing the top 100 papers in increments of 10-year periods showed no significant difference in the distribution of disruption scores over time. No correlation between an article's citation count and disruption score was established. Additionally, no significant relation between the number of authors/study design and disruption scores was identified.
    CONCLUSION: The disruption score highlights significant impact elements not entirely accounted for by citation count. Its potential benefit in assessing scientific impact should be contemplated.
    DOI:  https://doi.org/10.1016/j.crad.2022.07.003
  32. Healthcare (Basel). 2022 Sep 05. pii: 1701. [Epub ahead of print]10(9):
      The growing use of information and communication technology has now expanded to health professionals in practice. This study aimed to highlight the current status of Information and Communication Technology (ICT) use in health sciences as reported in journal papers between 2002 and 2021. This paper presents the annual trends, top institutes and countries, citations, h-index, keywords distribution, and top authors in this research domain. The data were extracted from the Web of Science database, and R studio and Bibexcel tools were used for analysis. The study analyzed a total of 140 documents published over a span of two decades. Health Care Sciences Services (34) and Computer Science published the most health science articles (29). The USA (19) was the most productive country, followed by England (16) and the Netherlands (15). Berg M was the most productive author, with 36 articles. The results show that institutions such as Erasmus University and Duke University have published numerous articles on the topic, encouraged by specific R&D funding schemes, and made a significant contribution to the development of health sciences research. The findings of this study offer valuable information about international initiatives and projects relevant to the advancement of ICT in health science research, which may be utilized to pinpoint potential future study topics such as artificial intelligence development.
    Keywords:  ICT; citation; h-index; health science; scientometric
    DOI:  https://doi.org/10.3390/healthcare10091701
  33. PLoS One. 2022 ;17(9): e0274802
       OBJECTIVES: To explore and analyze research hotspots and frontiers in CRF in ovarian cancer patients to provide an evidence-based basis for scholars and policymakers.
    BACKGROUND: Ovarian cancer is one of the most common and lethal gynecological malignancies. Cancer-related fatigue (CRF) is an annoying and pervasive side-effect that seriously affects the activities of daily living and decreases the quality of life (QoL) of cancer survivors.
    METHODS: The literature was retrieved from the Web of Science Core Collection (WOSCC) from inception to 2021-12-31. CiteSpace was used to discuss research countries, institutions, authors, and keywords.
    RESULTS: This study ultimately included 755 valid publications, and the number of publications showed a gradual upward trend. The countries, institutions, authors, and journals that have published the most articles and cited the most frequently were the United States, the University of Texas MD Anderson Cancer Center, Michael Friedlander and Amit M Oza, Gynecologic Oncology, and Journal of Clinical Oncology. The top three high-frequency keywords were Ovarian cancer, chemotherapy, and clinical trial. The top three keywords with the strongest citation bursts were cyclophosphamide, double-blind, and open-label.
    CONCLUSIONS: Conducting multi-center, large-sample, randomized controlled clinical trials to determine whether chemotherapeutic agents have severe adverse effects and to discuss the relationship between CRF and QoL and overall survival in cancer survivors are hotspots in this field. The new trends may be applying double-blind, randomized controlled trials to clarify the causes of CRF and open-label, randomized trials to determine the efficacy, safety, and tolerability of chemotherapeutic agents.
    DOI:  https://doi.org/10.1371/journal.pone.0274802
  34. Front Integr Neurosci. 2022 ;16 940265
      Mammalian target of rapamycin (mTOR) is an important molecule that regulates cell metabolism, growth, and proliferation in the nervous system. This study aimed to present the current study hot spots and predict the future development trend of the mTOR pathway in neurologic diseases using bibliometrics. We referred to the publications in the Web of Science Core Collection database. VOSviewer and CiteSpace programs were used to evaluate countries/regions, institutions, authors, journals, keywords, and citations showing the current study focus and predicting the future trend of mTOR in neuroscience. The search date ended on 19 June 2022, and there were 3,029 articles on mTOR in neuroscience from 2002 to 2021. Visual analysis showed that although the number of publications declined slightly in some years, the number of publications related to mTOR generally showed an upward trend, reaching its peak in 2021. It had the largest number of publications in the United States. Keywords and literature analysis showed that protein synthesis regulation, ischemia, mitochondrial dysfunction, oxidative stress, and neuroinflammation may be hot spots and future directions of the nervous system in mTOR studies. Recently, the most studied neurological diseases are Alzheimer's disease (AD), tuberous sclerosis complex (TSC), and depression, which are still worthy of further studies by researchers in the future. This can provide a useful reference for future researchers to study mTOR further in the field of neuroscience.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; citations; mTOR; neuroscience
    DOI:  https://doi.org/10.3389/fnint.2022.940265
  35. Front Oncol. 2022 ;12 957370
      
    Keywords:  CiteSpace; acute myeloid leukemia; aml; bibliometric analysis; targeted therapy
    DOI:  https://doi.org/10.3389/fonc.2022.957370
  36. Open Forum Infect Dis. 2022 Sep;9(9): ofac415
       Background: The landscape of infectious diseases research by interprofessional teams continues to change in both scope and engagement. Limited information exists regarding publication metrics and factors associated with publication of abstracts presented at professional infectious diseases meetings.
    Methods: This was a retrospective, observational study evaluating abstracts presented at IDWeek in 2017 and 2018. The primary endpoint was the proportion of abstracts that were subsequently published in peer-reviewed journals. Factors associated with publication were evaluated, and a description of publication metrics was reported.
    Results: Of the 887 abstracts analyzed from the IDWeek meetings, 236 (26.6%) were published. Significantly more abstracts were published if they were presented as a platform presentation versus poster presentation (35% vs 21%, P < .001). Inclusion of a PhD author significantly increased the likelihood of publication (P = .0014). Prospective studies, greater number of authors, and greater number of study subjects were more common among published abstracts. Median time to publication was 10.9 months, and the majority were published in infectious diseases journals, with an overall average impact factor of 7.7 across all journals.
    Conclusions: Abstracts from IDWeek presented as oral platforms and those including a PhD author were more likely to be published. Large, diverse authorship teams were common among published abstracts. The high quality of resulting manuscripts is evident by the destination journals and their respective impact factors. These data may be used to inform and motivate clinicians and trainees engaging in infectious diseases-related research.
    Keywords:  IDSA; IDWeek; abstracts; academician; publications; research
    DOI:  https://doi.org/10.1093/ofid/ofac415
  37. Front Public Health. 2022 ;10 925475
       Background: Autism spectrum disorders (ASD) are heterogeneous neurodevelopmental conditions that affect people worldwide. Early diagnosis and clinical support help achieve good outcomes. However, medical system structure and restricted resource availability create challenges that increase the risk of poor outcomes. Understanding the research progress of childhood ASD in recent years, based on clinical literature reports, can give relevant researchers and rehabilitation therapists more resonable research guides.
    Objective: This bibliometric study aimed to summarize themes and trends in research on childhood ASD and to suggest directions for future enquiry.
    Methods: Citations were downloaded from the Web of Science Core Collection database on childhood ASD published from 1 January 2012, to 31 December 2021. The retrieved information was analyzed using CiteSpace.5.8. R3, and VOS viewer.
    Results: A total of 7,611 papers were published across 103 areas. The United States was the leading source of publications. The clusters that have continued into 2020 include coronavirus disease 2019, gut microbiota, and physical activity, which represent key research topics. Keywords with frequency spikes during 2018-2021 were "disabilities monitoring network," "United States," and "caregiver."
    Conclusions: The Autism and Developmental Disabilities Monitoring Network in the United States can be used as a reference for relevant workers worldwide. An intelligent medical assistant system is being developed. Further studies are required to elucidate challenges associated with caring for a child with ASD.
    Keywords:  CiteSpace; VOSviewer; autism spectrum disorders; bibliometrics; children
    DOI:  https://doi.org/10.3389/fpubh.2022.925475
  38. Diagnostics (Basel). 2022 Sep 16. pii: 2238. [Epub ahead of print]12(9):
      There has been a steady increase (annual percentage growth rate of 19.2%, average of 18.3 citations per document) in capsule endoscopy (CE) publications from a global, interdisciplinary research community on a growing range of CE applications over the last 20+ years. We here present the status of CE as a field of research, tracing its evolution over time and providing insight into its potential for diagnostics, prevention and treatment of gastrointestinal (GI) tract diseases. To portray the development of the CE research landscape in the 2000-2021 time span, we analyzed 5764 scientific publications. Analyses were performed using the R language and environment for statistical computing and graphics and VOSviewer, a software developed for scientific literature analysis by scientometricians. The aim of this paper is to provide a wide comprehensive analysis of the trends in CE publications. We thus performed subgroup analysis on the selected papers, including indications, annual percentage growth rate, average citations per document, most publications from research areas/interdisciplinary field of the articles, geography, collaboration networks through institutions, specific clinical keywords and device type. The firm increase in CE publications over the last two decades highlights the overall strength of the technology in GI applications. Furthermore, the introduction to the field of artificial intelligence (AI) tools has been promoting a range of technological advances that keep on affecting the diagnostic potential of CE.
    Keywords:  capsule endoscopy; meta-view; research
    DOI:  https://doi.org/10.3390/diagnostics12092238
  39. Geriatrics (Basel). 2022 Sep 03. pii: 90. [Epub ahead of print]7(5):
      Gender equality, with an emphasis on female education, has been designated by the United Nations as one of the 17 Sustainable Development Goals (SDGs) to be completed by 2030, since gender disparity is a major impediment to scientific and economic progress. This study was carried out in an effort to address the gender gaps that can be seen in academic and scientific publications. The purpose of this study is to describe the gender distribution of editorial board members and editors-in-chief across geriatrics journals with high impact factors. Clarivate Journal Citation Reports (JCR) 2021 were used to guide the selection of geriatric and gerontology journals utilizing Scopus All Science Journal Classification Codes. The genders of the editors-in-chief and editorial board members were determined and analyzed using publicly accessible data. A total of 47 geriatric journals with an average impact factor of 4.27 were examined. Of the 65 editors-in-chief, 21 (32%) were women, whereas 876 female editorial members were found out of a total of 2414, which constitutes 36% in total. Despite making up 60% of the geriatric medical workforce, women are still underrepresented on editorial boards and as chief editors in well-known geriatric periodicals.
    Keywords:  gender disparity; geriatrics; women in geriatrics
    DOI:  https://doi.org/10.3390/geriatrics7050090
  40. Poult Sci. 2022 Aug 13. pii: S0032-5791(22)00423-0. [Epub ahead of print]101(11): 102134
      To have a better contribution to the poultry production community, the Poultry Science Association founded journals including Poultry Science (PS) at 1921. Now, after 100 yr of publishing, PS ranks between the top 10 journals in the category of "agriculture, dairy, and animal science". One hundred years after publishing the first paper in PS, the poultry industry has been completely revolutionized. Hence, it will be interesting to establish scientometrics study of the PS development during the last century. Therefore, based on findings of the current study, among countries/authors' collaborations, future research fronts, and possibility of hot topics in the coming years may be predictable. Accordingly, a total of 22,451 articles were retrieved. For content analyses, according to the PS categorization for subject areas, 14 different subject areas were developed, including "behavior, breeding and quantitative genetics, education and extension, health and welfare, immunology, management and environment, metabolism and nutrition, microbiology and virology, modeling, molecular biology, physiology and anatomy, production, products, processing and marketing, and reproduction". Considering the 100-yr of PS, the most frequent subject area was "nutrition and metabolism" (14,109 articles), and "modeling" (1,114 articles) attracted less scholarly attention. However, considering the last decade (2011-2020), the most important subject area was "molecular biology" (1,420 of 2,466 articles; 57.58%), followed by "modeling" (544 of 1,144 articles; 48.88%). Moreover, the most frequent poultry species/strains were broilers (retrieved in 6,156 articles), followed by laying hens, turkeys, and quail. Considering collaboration of countries and researchers, it can be said that a total number of 108 countries contributed to PS, with the most prolific country being United States (with 9,421 articles; 43.16%), followed by China, Canada, the Netherlands, and Japan. Among the authors, Harms RH (287 articles), and Siegel PB (208) were the most prolific authors, and Siegel PB and Dunnington EA (71 articles) had more collaborations. To study keyword trends, including 3 time periods broilers was the central co-occurrent keyword, while the importance of chickens and turkeys declined during the time. Salmonella spp. was a constant representative of poultry microbiology during 100 yr. While "nutrition and metabolism" was the most important subject area, nutrition-related keywords (major items) were not concentrated and co-occurred with a variety of keywords from different subject areas. While "molecular biology" ranked first over the past decade, the importance of "nutrition and metabolism" should not be ignored. In fact, in recent years, molecular basis of the nutrition has been studied. In big-data era and due to developing the molecular biology technologies, it seems that using mathematical modeling and computational methodologies will increase and probably remains as one of the most attractive research areas for scientists at least in the upcoming future decades.
    Keywords:  collaboration; content analyses; research fronts; scientometrics; subject areas
    DOI:  https://doi.org/10.1016/j.psj.2022.102134
  41. Trop Med Health. 2022 Sep 21. 50(1): 70
       BACKGROUND: The national malaria control policy in the Central African Republic (CAR) promotes basic, clinical, and operational research on malaria in collaboration with national and international research institutions. Preparatory work for the elaboration of National Strategic Plans for the implementation of the national malaria control policy includes developing the research component, thus requiring an overview of national malaria research. Here, this survey aims to provide an inventory of malaria research as a baseline for guiding researchers and health authorities in choosing the future avenues of research.
    METHODS: Data sources and search strategy were defined to query the online Medline/PubMed database using the "medical subject headings" tool. Eligibility and study inclusion criteria were applied to the selected articles, which were classified based on year, research institute affiliations, and research topic.
    RESULTS: A total of 118 articles were retrieved and 51 articles were ultimately chosen for the bibliometric analysis. The number of publications on malaria has increased over time from 1987 to 2020. These articles were published in 32 different journals, the most represented being the Malaria Journal (13.73%) and the American Journal of Tropical Medicine and Hygiene (11.76%). The leading research topics were drug evaluation (52.94%), expatriate patients (23.54%), malaria in children (17.65%), morbidity (13.7%), and malaria during pregnancy (11.76%). The publications' authors were mainly affiliated with the Institut Pasteur of Bangui (41%), the French Military Medical Service (15.5%), and the University of Bangui (11.7%). Collaborations were mostly established with France, the UK, and the USA; some collaborations involved Switzerland, Austria, Pakistan, Japan, Sri Lanka, Benin, Cameroun, Ivory Coast, and Madagascar. The main sources of research funding were French agencies (28.6%) and international agencies (18.3%). Most studies included were not representative of the whole country. The CAR has the capacity to carry out research on malaria and to ensure the necessary collaborations.
    CONCLUSION: Malaria research activities in the CAR seem to reflect the priorities of national policy. One remaining challenge is to develop a more representative approach to better characterize malaria cases across the country. Finally, future research and control measures need to integrate the effect of COVID-19.
    Keywords:  Central African Republic; Control policy; Database; Malaria research; Publication output
    DOI:  https://doi.org/10.1186/s41182-022-00446-z
  42. Med J Islam Repub Iran. 2022 ;36 65
      Background: Mapping scientific trends is one of the most important missions of scientometric research for effective research. The main goal of this paper was to visualize and draw the intellectual and cognitive structures of information retrieval (IR) in the medical sciences using science mapping. Methods: In this cross-sectional scientometric study, we recruited all documents indexed in the Web of Science database with the topic of storing and retrieval of information in medical sciences. To analyze the results, 3 software, SciMAT-v1.1.04, VOSviewer-v1.6.14, CitNetExplorer_v1.0.0, were used. Results: Our results showed that most scientific productions in this field fall into 2 categories: (1) effective methods of organizing information and (2) application and operation of the IR system in the process of intelligent questioning and answering, and analyzing information behaviors of physicians and health professionals. The results showed that the similarity index increased over time from 0.43 to 0.71. Analysis of the findings showed that similarity measures, expert systems, concepts, experience, answers, and multimodel IR clusters were considered as mature and completely centralized clusters in the first quarter of the strategic chart. Conclusion: Because of the dramatic approximation of the vocabulary used by researchers and a relative slowdown in the growth rate of the subject's domain in the last decade, it seems necessary to pay attention to the expansion of the fields of IR and the application of its concepts in medical information sciences. Also, it can be recommended that designers of IR systems and techniques in medical information sciences pay more attention to human factors attentively to develop new technologies and tools.
    Keywords:  Citation Network; Information Retrieval; Medical And Health Science; Research Trends; Scientometric
    DOI:  https://doi.org/10.47176/mjiri.36.65
  43. PLoS One. 2022 ;17(9): e0274810
      Can the male citation advantage (more citations for papers written by male than female scientists) be explained by gender homophily bias, i.e., the preference of scientists to cite other scientists of the same gender category? Previous studies report much evidence that this is the case. However, the observed gender homophily bias may be overestimated by overlooking structural aspects such as the gender composition of research topics in which scientists specialize. When controlling for research topics at a high level of granularity, there is only little evidence for a gender homophily bias in citation decisions. Our study points out the importance of controlling structural aspects such as gendered specialization in research topics when investigating gender bias in science.
    DOI:  https://doi.org/10.1371/journal.pone.0274810
  44. Int J Environ Res Public Health. 2022 Sep 09. pii: 11343. [Epub ahead of print]19(18):
      Reducing the effect of mankind's activities on the climate and improving adaptability to global warming have become urgent matters. The carbon footprint (CF), derived from the concept of ecological footprint, has been used to assess the threat of climate change in recent years. As a "top to bottom" method, input-output analysis (IOA) has become a universally applicable CF assessment tool for tracing the carbon footprint embodied in economic activities. A wide range of CF studies from the perspective of the IOA model have been presented and have made great progress. It is crucial to have a better understanding of what the relevant research focuses on in this field, yet so far a systematic synopsis of the literature is missing. The purpose of this paper is to explore the knowledge structure and frontier trends in respect of the IOA model applied to CF research using scientometric visualization analysis. The main findings of this paper are as follows. (1) Published articles show a two-stage increase in the period 2008 to 2021, and present a complex academic network of countries, authors, and institutions in this important domain. (2) The classic studies are mainly divided into three categories: literature reviews, database application introduction, and CF accounting in different scales. (3) The research hotspots and trends show that the research scales tend to be more microscopic and applications of models tend to be more detailed. In addition, supply-chain analysis and driver-factor analysis will probably become the main research directions in the future.
    Keywords:  carbon footprint; input–output model; knowledge-mapping analysis; visual analysis
    DOI:  https://doi.org/10.3390/ijerph191811343
  45. Foods. 2022 Sep 16. pii: 2870. [Epub ahead of print]11(18):
      This study aimed to conduct a systematic literature review (SLR) of the research performed in the plant-based meat analogues area. Historical, current, and future tendencies are discussed. The paper offers a comprehensive SLR coupled with a bibliometric analysis of the publication from 1972 to January 2022. The articles were obtained using a research string and precise inclusion and exclusion criteria from two prominent databases, Scopus and Web of Science (WoS). The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow technique was used to describe the data screening and selection. In total, 84 publications were selected for further analysis after a thorough literature assessment. From this study, six main themes were identified: (1) objectives of the study; (2) type of plant protein; (3) product type; (4) added ingredients; (5) texturization technique; and (6) quality assessment considered in the studies. Recent trends in publication imply that meat analogue technology is gaining prominence. This review revealed significant research on improving meat analogues via texturization. Even though extrusion is used industrially, the technique is still in its infancy and needs improvement. Future studies should focus more on fiber and protein-protein interactions, macromolecule conformation and mechanisms, diversifying or improving current methods, sensory attributes, and gastrointestinal absorption rate of each novel protein ingredient.
    Keywords:  alternative proteins; bibliometric analysis; extrusion cooking; high-moisture meat analogues (HMMA); meat analogues; meat substitutes; plant-based protein; systematic literature review (SLR); texturized vegetable protein (TVP); texturizing technique
    DOI:  https://doi.org/10.3390/foods11182870
  46. Eval Program Plann. 2022 Sep 05. pii: S0149-7189(22)00111-2. [Epub ahead of print]95 102157
      The discussion on the 'societal impact of university research' has emerged within the recent decade with different utilisation from the British REF impact stories to the EU Framework Programmes' criteria. The fundamental idea is that (university) research should contribute to addressing societal challenges, such as climate change, and not just pursue 'scientific excellence'. Several approaches have been developed, from case studies of the 'productive interactions' that co-create knowledge with societal stakeholders to the so-called 'altmetrics' tracking online dissemination of research outputs. Nonetheless, these experiences do not always point in the same direction, and the notion of 'societal impact' seems still unclearly defined. Given the growing policy pressure on universities to address societal challenges, this paper reviews the scientific literature on the so-called 'societal impact' of university research. By querying three scientific archives (Web of Science, Scopus and ScienceDirect), 135 relevant scientific publications are selected and discussed, looking for conceptualisations, monitoring methods and success factors. The review maps a value-laden discussion arguing for longer-term, multi-dimensional perspectives on university research impacts beyond bibliometric indicators. Findings highlight a progressive shift from 'attribution', i.e., looking for causal relationships between research and societal changes, to 'contribution', acknowledging researchers' efforts to engage with societal challenges.
    Keywords:  Altmetrics; Coproduction; Impact pathways; Research evaluation; Societal impact
    DOI:  https://doi.org/10.1016/j.evalprogplan.2022.102157
  47. Nature. 2022 Sep 19.
      
    Keywords:  Careers; Funding; Institutions
    DOI:  https://doi.org/10.1038/d41586-022-02984-2
  48. Mar Policy. 2022 Sep 12. 105285
      Fighting the COVID-19 pandemic has led to a dramatic increase in plastic waste, which has had a huge impact on the environment, including the marine environment. This work is aimed to evaluate the pattern of national research cooperation, research hotspots, and research evolution before and during the epidemic by systematically reviewing the publications on marine plastic pollution during 2015-2019 (before the pandemic) 2020-2022 (during the pandemic) using the Systematic Literature Review and Latent Semantic Analysis. The results show (i) Compared to pre-pandemic, publications on marine pollution during the COVID-19 pandemic declined briefly and then increased sharply. (ii) Compared with before the pandemic, the national cooperation model has changed during the pandemic, and four major research centers have been formed: Central European countries centered on Italy; Nordic countries centered on United Kingdom; South Korea; Asia and Africa centered on India A developing country and a Pacific Rim country centered on United States and China. (iii) The knowledge map of keyword clustering does not change significantly before and during the COVID-19: ecosystem, spatial distribution, environmental governance and biodegradation. However, there are differences in the sub-category research of the four types of keywords. (iv) The impact of marine plastics on organisms and the governance of marine plastic pollution have become a branch of knowledge that has evolved rapidly during the pandemic. The governance of marine plastic pollution and microplastics are expected to become an important research direction.
    Keywords:  Bibliometric analysis; COVID-19; Latent semantic analysis; Marine plastic pollution; Systematic literature review
    DOI:  https://doi.org/10.1016/j.marpol.2022.105285
  49. Int J Environ Res Public Health. 2022 Sep 13. pii: 11529. [Epub ahead of print]19(18):
      In the context of the coronavirus disease 2019 (COVID-19), people's social mentality and mental health have been severely affected, which has hindered or even reversed the achievement of the United Nations Sustainable Development Goals (SDGs). However, there is a lack of investigation into the potential relationship between social mentality and health, as well as of the comparison between different databases worldwide and in China, in the current context of COVID-19. Hence, the aim of this paper is to explore the research hotspots and development trends of social mentality and health in China and worldwide, while improving people's health, building a sustainable society, and facilitating the achieving of the SDGs. A bibliometric method is employed in this paper from a macro-quantitative and micro-qualitative perspective to explore the research hotspots and trends of social mentality and health in the world and China from the two databases, namely the English-language Web of Science (WOS) and the Chinese-language China National Knowledge Infrastructure (CNKI). The results indicate that: (1) By using keyword co-occurrence and clustering analysis via the CiteSpace software bibliometric tool, 11 current research hotspots have been identified and studies are increasing in terms of using the Chinese language and the English language. (2) The current studies in the CNKI database mainly focus on the macro social environmental factors affecting social mentality and population research, while the studies in the WOS database pay more attention to social mentality and health in the context of the COVID-19 epidemic situation and a variety of professions. Hence, future research could explore the influencing factors and cultivation methods toward a healthy social mentality from the perspective of methodology and toward achieving SDG 3, providing healthy lives and promote well-being for all at all ages, and SDG 11, building sustainable cities and communities in the post-pandemic COVID-19 era.
    Keywords:  COVID-19; bibliometric; city; comparative study; mental health; social mentality; sustainable development; youth
    DOI:  https://doi.org/10.3390/ijerph191811529
  50. Children (Basel). 2022 Aug 27. pii: 1300. [Epub ahead of print]9(9):
      There are numerous children and adolescents throughout the world who are either diagnosed with speech and language disorders or manifest any of them as a result of another disorder. Meanwhile, since the emergence of language as an innate capability, the question of whether it constitutes a behaviour or an innate ability has been debated for decades. There have been several theories developed that support and demonstrate the biological foundations of human language. Molecular evidence of the biological basis of language came from the FOXP2 gene, also known as the language gene. Taking a closer look at both human language and biology, biolinguistics is at the core of these inquiries-attempting to understand the aetiologies of the genetics of speech and language disorders in children and adolescents. This paper presents empirical evidence based on both scientometrics and bibliometrics. We collected data between 1935 and 2022 from Scopus, WOS, and Lens. A total of 1570 documents were analysed from Scopus, 1440 from the WOS, and 5275 from Lens. Bibliometric analysis was performed using Excel based on generated reports from these three databases. CiteSpace 5.8.R3 and VOSviewer 1.6.18 were used to conduct the scientometric analysis. Eight bibliometric and eight scientometric indicators were used to measure the development of the field of biolinguistics, including but not limited to the production size of knowledge, the most examined topics, and the most frequent concepts and variables. A major finding of our study is identifying the most examined topics in the genetics of speech and language disorders. These included: gestural communication, structural design, cultural evolution, neural network, language tools, human language faculty, evolutionary biology, molecular biology, and theoretical perspective on language evolution.
    Keywords:  FOXP2; biolinguistics; evo-devo; language biological bases; language faculty; language gene; nature–nurture dichotomy; scientometric review
    DOI:  https://doi.org/10.3390/children9091300
  51. Environ Geochem Health. 2022 Sep 21.
      Risk assessment has been recognized as an important tool for evaluating heavy metal pollution and providing risk-based information for decision makers. In order to accurately assess the risk of heavy metals in contaminated soil to human health, it is necessary to conduct bioavailability studies on heavy metals in soil. Bioavailability of heavy metals in soils and the implications for risk assessment and land management/remediation has evolved over the decades and now has considerable practical and economic implications internationally. This article aims to explore its evolution by undertaking a bibliometric analysis of the research fields which have addressed heavy metal bioavailability in soils, with a focus on the risk assessment of contaminated land and human exposure to soil-borne metals. Bibliometric analysis techniques are applied to monitor and assess the changing research literature on the bioavailability of heavy metals in contaminated soils. Over 5000 articles were found for the period 1979-2020. The purpose was not to perform an exhaustive literature review, but to draw out trends and patterns in the literature, and to make observations on past and current priorities. Key words were extracted from the analysis and the roles of different countries in driving the research literature identified. Three phases in literature/subject development were identified. Between 1979 and 2000 (initial phase, 213 articles), studies used extraction procedures and solubility studies to investigate the roles of soil properties on metal form/speciation and focused on bioavailability to (crop) plants in agricultural soils. Between 2001 and 2010 (slow development phase, 1105 articles), attention switched to metals introduced in soil amendments and wastes, metal impacts on soil microbial processes, and incorporating bioavailability in risk assessment. More rigorous techniques were being used, such as the diffusive gradients in thin films technique, to better understand kinetic and metal speciation in soils and the quantitative relationship to bioavailability. By 2011-2020 (rapid development phase, 3137 articles), research was being conducted in many countries (site specific, often industrially contaminated and urban sites), with a focus shift to health risk assessment, remediation, and bioavailability to various ecological receptors (e.g., humans and animals), with the development of many methods of bioavailability (e.g., simulated gastrointestinal tract enzymolysis methods). Some priorities for research on soil heavy metal bioavailability are identified.
    Keywords:  Bibliometric; Bioavailability; Contaminated soil; Heavy metal; Phase development
    DOI:  https://doi.org/10.1007/s10653-022-01387-6
  52. Genes (Basel). 2022 Sep 14. pii: 1646. [Epub ahead of print]13(9):
      Genetic research in Autism Spectrum Disorder (ASD) has progressed tremendously in recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence, expression, epigenetic transformation, and interactions with other physiological and environmental systems have been found to increase the likelihood of developing ASD. There is therefore a need to represent this wide-ranging yet voluminous body of literature in a systematic manner so that this information can be synthesised and understood at a macro level. Therefore, this study made use of scientometric methods, particularly document co-citation analysis (DCA), to systematically review literature on ASD genetic research from 2018 to 2022. A total of 14,818 articles were extracted from Scopus and analyzed with CiteSpace. An optimized DCA analysis revealed that recent literature on ASD genetic research can be broadly organised into 12 major clusters representing various sub-topics. These clusters are briefly described in the manuscript and potential applications of this study are discussed.
    Keywords:  ASD; Autism Spectrum Disorder; CiteSpace; autism; genetics; scientometrics
    DOI:  https://doi.org/10.3390/genes13091646
  53. Int J Environ Res Public Health. 2022 Sep 12. pii: 11475. [Epub ahead of print]19(18):
      The world is undergoing an unprecedented trend of fast urbanization, which causes a range of socio-environmental consequences, one of which is shrinking cities and towns (SCT). SCT refer to the cities or towns that are experiencing population decline and economic downturn. In the existing literature, there have been numerous studies on SCT; however, there is a lack of study which investigates its knowledge domains. Therefore, this paper aims to conduct a scientometric analysis to achieve an outline of the SCT research status. Through the procedures of literature search and screening, a total of 716 SCT-related studies were extracted from the Scopus. The VOSviewer software system program was then utilized to visualize the present SCT-related studies. The visualization results revealed that the journal of Sustainability made significant contributions to the SCT research in terms of relevant publications. In addition, Haase, Annegret received the most co-citations, and was also the most productive author in this field. Furthermore, it was identified that current SCT research is mainly conducted in developed countries. Through the analysis of keywords, the emerging research topics were revealed. Discussions were further made from the perspectives of prevailing research methods, evaluation criteria, and solutions for SCT problems.
    Keywords:  knowledge mapping; resilience; shrinking cities and towns; urbanization; visualization
    DOI:  https://doi.org/10.3390/ijerph191811475
  54. BMJ Support Palliat Care. 2022 Sep 21. pii: spcare-2022-003820. [Epub ahead of print]
       OBJECTIVE: There is a growing interest in developing a scientific research metric to assess the level of palliative care (PC) development in countries. This study assesses a metric based on publishing in specialised PC journals as an indicator for the level of PC development.
    METHODS: A 3-year average articles per million population per year (3y-AAMY) metric was calculated using documents published in 19 specialised PC journals indexed in Scopus database. Countries were categorised into six levels starting with level '0' with no publications then levels Q1 to Q5 according to the 3y-AAMY quintiles (Q5=best performance). The relationship between the 3y-AAMY and the level of PC development in countries and opioid consumption figures was tested.
    RESULTS: During 2016-2018, 6610 eligible documents were published in the selected 19 journals. The median (IQR) 3y-AAMY of 191 countries was 0.0123 (0-0.237). The 3y-AAMY differed significantly among the levels of PC development, being 0 (IQR:0-0) for category 1 (no known activity) countries and 1.129 (IQR:0.286-4.625) for category 4B (advanced integration) countries (Kruskal-Wallis test p<0.000001 and Jonckheere-Terpstra trend test p<0.00001). The correlation between the 3y-AAMY and average opioid consumption was a highly significant positive one (Spearman's ρ=0.681, p<0.0001). Furthermore, opioid consumption differed significantly between the 3y-AAMY categories being highest for Q5 countries (Kruskal-Wallis test p<0.000001 and Jonckheere-Terpstra trend test p<0.00001).
    CONCLUSION: A metric based on publishing in specialised PC journals correlates significantly with the levels of PC development and opioid consumption in countries and may be used alongside other indicators for the assessment of PC development.
    Keywords:  Service evaluation
    DOI:  https://doi.org/10.1136/spcare-2022-003820
  55. Cien Saude Colet. 2022 Oct;pii: S1413-81232022001003975. [Epub ahead of print]27(10): 3975-3985
      The scope of this research outlines the field of study on public health policies for youth supported by bibliometric maps, from the perspective of identifying research gaps. VOSviewer software was used based on the exploratory-descriptive profile, with data located in October 2021, using the key words "public", "youth", "health" with the connecting "and", which resulted in 172 articles. The following groupings were located: co-authorship by country; co-authorship by key words; co-quote by article; co-quote by reference cited; bibliographic coupling; co-quote of authors. The results reveal an interdisciplinary field, represented by studies in the areas of education, social work, law, and social sciences, with a significant recurrence of the themes of mental health, violence, and obesity, as well as discussions on substance use and abuse, such as cigarette smoking for example. Debates about the social configuration, defined by the idea of community, as well as its prevalence and prevention are present in the scope of these studies. Finally, eight research agenda topics are derived from the discussion about the growing movement towards health promotion as a public policy, while socio-economic and cultural aspects are presented with greater emphasis, in the quest to understand the impacts of this scenario for youth.
    DOI:  https://doi.org/10.1590/1413-812320222710.04812022
  56. Int J Environ Res Public Health. 2022 Sep 08. pii: 11305. [Epub ahead of print]19(18):
      Climate change communication is a crucial strategy for addressing the major challenges of climate change, and the knowledge mapping analysis and overview of it helps to clarify research progress. Based on CiteSpace, 428 pieces of domestic and foreign literature are collected to clarify the basic status of climate change communication research and summarize research hotspots and prospects. The study found that: (1) The earliest traceable English literature on climate change communication appeared in 2000. The number of articles published has risen steadily since 2008, reaching its first peak in 2015. (2) In contrast, research into Chinese climate change communication began late and progressed slowly. The Chinese literature on climate change communication first appeared in 2009. Although domestic research generally continues to pay attention to this phenomenon, there is still room for development compared with international research. (3) The research hotspots for climate change communication are obtained through keyword co-occurrence analysis. Public perceptions of climate change are strongly influenced by political ideology. Since climate change has political attributes, people from different political parties or groups form their views on climate change through identity protection. (4) The research content on climate change communication can be summarized into the following six aspects: the development of climate change communication research; differences in public perceptions of climate change; factors influencing climate change communication; key elements of the climate change communication process; the important role of the media in climate change communication; and effective strategies for climate change communication. Finally, the shortcomings of this study are summarized and future research prospects on climate change communication are put forward from the perspectives of research methods, research contexts, and research paradigms.
    Keywords:  CiteSpace; climate change communication; knowledge mapping; literature review
    DOI:  https://doi.org/10.3390/ijerph191811305
  57. Toxics. 2022 Sep 01. pii: 523. [Epub ahead of print]10(9):
      Triclosan (TCS) is a widely used chemical whose effects on human health remains elusive. TCS may play a role in a variety of health issues, including endocrine dysfunction, irregular embryonic development, and immune suppression. It is possible that TCS's penetrative abilities across all body barriers, including the blood-brain barrier, may make bioaccumulation the primary driver of these issues. In addition, chronic overuse of this chemical in everyday life may further contribute to the already increasing problem of antibiotic resistance. TCS research has steadily increased since its transition from medical to commercial use over the last 50 years. However, there are some clear gaps in the depth of this research as the safety of this agent is not fully agreed upon. The Food and Drug Administration recently issued regulatory rules regarding TCS in some commercial products; however, it is still found in a variety of goods marketed as "antimicrobial" or "antibacterial". The purpose of this bibliometric study is to analyze research trends in this field and determine the amount of global attention TCS has received as to its relevancy in human health. Documenting and determining research concentration trends related to this field may outline where additional research is most necessary, as well as demonstrate the most valuable research produced and its relation to the advancement of our understanding of TCS. We found there to be a shift in research from TCS and its role in medical environments, to research based on the indirect effects of TCS through environmental contaminations, such as the propagation of antibiotic resistance. This shift was coupled with an increase in global research related to this field and identified China as a significant contributor. Although TCS has received notice, the simple fact of its continued use in so many common products, as well as the unclear understanding of its direct health impacts, reinforces the need for additional and more conclusive research before it has possible irreversible effects on our environment and health.
    Keywords:  bibliometrics; human health; triclosan
    DOI:  https://doi.org/10.3390/toxics10090523
  58. J Autism Dev Disord. 2022 Sep 20.
       PURPOSE: Ever since Leo Kanner first described autism in 1943, the research in this field has grown immensely. In 2021 alone, 5837 SCOPUS indexed documents were published with a title that contained the words: "autism", "autistic", or "ASD". The purpose of this study was to examine the most common topics of autism research in 2021 and present a geographical contribution to this research.
    METHODS: We performed a content analysis of 1102 abstracts from the articles published in 11 Autism journals in 2021. The following journals, indexed by the SCOPUS database, were included: Autism, Autism Research, Molecular Autism, Journal of Autism and Developmental Disorders, Research in Autism Spectrum Disorders, Focus on Autism and Other Developmental Disabilities, Education and Training in Autism and Developmental Disabilities, Review Journal of Autism and Developmental Disorders, Advances in Autism, Autism and Developmental Language Impairments, and Autism in Adulthood.
    RESULTS: According to the analysis, the main research topics were: mental health, social communication, social skills, quality of life, parenting stress, ADHD, Covid-19, self-efficacy, special education, and theory of mind. In relation to geographic distribution, most studies came from the USA, followed by the UK, Australia, and Canada.
    CONCLUSION: Research topics were aligned with the priorities set by stakeholders in autism, most notably persons with autism themselves and their family members. There is a big gap in research production between developed countries and developing countries.
    Keywords:  Autism journals; Content analysis; Research topics; SCOPUS
    DOI:  https://doi.org/10.1007/s10803-022-05751-4
  59. Scand J Gastroenterol. 2022 Sep 19. 1-10
      As lncRNAs are essential participants in colorectal carcinogenesis. This study aimed to use the VOSviewer tool to access the research cores and frontiers on the relationship between lncRNAs and CRC. Our findings showed that the mechanism of lncRNA in the occurrence and development of CRC was the core theme of the field. (1) Immunotherapy and immune microenvironment of CRC and lncRNAs, (2) CRC and lncRNAs in exosomes and (3) CRC and lncRNA-targeted therapy might represent three research frontiers. A comprehensive understanding of their existing mechanisms and the search for new regulatory paradigms are the core topics of future research. This knowledge will also help us select appropriate targeting methods and select appropriate preclinical models to promote clinical translation and ultimately achieve precise treatment of CRC.
    Keywords:  CRC; bibliometric analysis; lncRNA; precision treatment; research trend
    DOI:  https://doi.org/10.1080/00365521.2022.2124537
  60. Front Med (Lausanne). 2022 ;9 982664
      The need for promoting diversity and equitable authorship representation in academics faces increasing recognition, with some articles pointing out the lack of diversity in specific fields. Currently, there are no such articles scrutinizing the author diversity in the field of Gastroenterology. Cochrane systematic reviews are perceived worldwide to be amongst the highest quality of evidence available, thereby its conclusions often impact policy and practice globally. However, little is known about the current state of authorship diversity in Gastroenterology-related Cochrane reviews.
    Keywords:  academic Gastroenterology; authorship; bias; diversity; gender
    DOI:  https://doi.org/10.3389/fmed.2022.982664
  61. Int J Environ Res Public Health. 2022 Sep 07. pii: 11260. [Epub ahead of print]19(18):
      One Health, a multidisciplinary approach to public health, which integrates human, animal, and environmental studies, is prudent for circumpolar Arctic health research. The objective of our bibliometric review was to identify and compare research in select infectious diseases in Arctic wildlife species with importance to human health indexed in English language databases (PubMed, Scopus) and the Russian database eLibrary.ru. Included articles (in English and Russian languages) needed to meet the following criteria: (1) data comes from the Arctic, (2) articles report original research or surveillance reports, (3) articles were published between 1990 and 2018, and (4) research relates to naturally occurring infections. Of the included articles (total n = 352), most were from Russia (n = 131, 37%), Norway (n = 58, 16%), Canada (n = 39, 11%), and Alaska (n = 39, 11%). Frequently reported infectious agents among selected mammals were Trichinella spp. (n = 39), Brucella spp. (n = 25), rabies virus (n = 11), Echinococcus spp. (n = 10), and Francisella tularensis (n = 9). There were 25 articles on anthrax in eLibrary.ru, while there were none in the other two databases. We identified future directions where opportunities for further research, collaboration, systematic reviews, or monitoring programs are possible and needed.
    Keywords:  Arctic; One Health; bibliometric review; infectious disease; wildlife health; zoonosis
    DOI:  https://doi.org/10.3390/ijerph191811260
  62. World Neurosurg. 2022 Sep 16. pii: S1878-8750(22)01328-6. [Epub ahead of print]
       BACKGROUND: The COVID-19 pandemic committees of all countries restricted face-to-face interactions. This study aimed to determine how the pandemic changed the research output for many neurosurgeons while highlighting how social media may have been used as a contactless platform to maintain research productivity during these times.
    METHODS: A cross-sectional, descriptive, 24-item, non-randomized online survey was applied worldwide and shared using social media platforms and emails. The questions mainly focused on comparing the results of the pre-pandemic period to the pandemic period (after March 2020).
    RESULTS: A total of 202 respondents from 60 different countries responded to the survey. Interest in neurosurgical education increased from 24% to 76%, while the topic of epidemiology gained interest from 28% to 72% when the pre-pandemic era was compared to the pandemic era. Preference for prospective studies decreased from 66% to 34%, while interest in retrospective studies increased from 39% to 61%. In evaluating publication types, the preference for reviews increased from 36% to 64%. Sixty-two percent of respondents stated they had concerns over delays in individual contributions/lack of accountability. These concerns were followed by problems with theft of intellectual property/data and authorship disputes. Forty-one percent believed that the support of extra hands on a load-heavy project was the most powerful benefit of social media collaboration. Those who reported increased publications during the pandemic were also more likely to collaborate using social media (p = 0.030).
    CONCLUSION: During the pandemic, social media collaborations helped increase research output for neurosurgeons.
    Keywords:  COVID-19; collaboration; pandemic; productivity; research; scholarly collaboration network; social media
    DOI:  https://doi.org/10.1016/j.wneu.2022.09.051
  63. Heliyon. 2022 Sep;8(9): e10510
      Increasing lecturers' research productivity plays a crucial role in improving teaching quality and university prestige. This research aims to establish and test a model for evaluating management factors that affect the research productivity of Vietnamese university lecturers. Data were collected by surveying 398 lecturers and researchers at universities affiliated with the Vietnam National University, Hanoi (VNU). Structural equation modeling (SEM) methodology was applied for data analysis. The research outcomes indicate that resources and policies to favor research activities are the two most influential factors affecting research productivity in lecturers. The decentralization factor, in contrast, did not show statistical significance, since its p-value was greater than 0.05. Based on the results obtained, several policy recommendations are proposed, namely: (i) ensuring resources for faculty's scientific research activities; (ii) improving policies for lecturers to enhance their scientific research achievements: (iii) developing strategies for scientific research activities; (iv) enhancing awareness of affiliated unit leaders about the importance of scientific research.
    Keywords:  Management; Research productivity; Resources for scientific research; Structural equation modeling
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e10510
  64. Mol Biol Cell. 2022 Oct 01. 33(12): pe6
      Although the process of publishing a scientific paper has gotten simpler, it is increasingly difficult to publish a paper in high profile journals. We have analyzed the publishing data in the cell biology field and found several alarming trends developing over the last two decades. There is an emerging divide between scientist-run journals and professional-run high profile journals. How did this happen? What should we do? The core issue is whether the current standard for high profile journals hurts rather than helps the scientific discovery process. In this regard, we suggest that the editors and scientists should direct their focus on the potential impact and rigor of the work instead of the "perfection" or "completeness" of the study.
    DOI:  https://doi.org/10.1091/mbc.E22-04-0140