bims-evares Biomed News
on Evaluation of research
Issue of 2022–06–05
forty-six papers selected by
Thomas Krichel, Open Library Society



  1. Perfusion. 2022 May 30. 2676591221105405
       AIM: Although the number of global studies on ECMO, which is an important support system in the treatment of COVID-19 related respiratory failure, has increased in recent months, there is still no bibliometric study on the use of ECMO in COVID-19 in the literature. The aim of this study is to analyze the scientific articles on the use of ECMO in COVID-19 by statistical and bibliometric methods.
    METHOD: Articles published between 2019-2022 about the use of ECMO in COVID-19 were obtained from the Web of Science (WoS) database and analyzed using statistical and bibliometric methods. Spearman correlation coefficient was used for correlation studies. Network visualization maps were used to identify effe analysis and trending topics.
    RESULTS: A total of 1197 publications were found. 758 (63.3%) of these publications were articles. The top 3 contributing countries to the literature were USA (257, 33.9%), Germany (102, 13.4%) and Japan (87, 11.5%). The top 3 most active institutions were League of European Research Universities (90), Harvard University (50), and Udice French Research Universities (39). The top 3 journals with the highest count of publications were ASAIO Journal (n = 36), Frontiers in Medicine (22), and Perfusion-UK (n = 20). According to the average count of citations per article, the most influential journals were JAMA (1319), Intensive Care Medicine (327), and Lancet (95.7), respectively. We have shared a summary of 758 articles in this comprehensive bibliometric study on the use of ECMO in COVID-19.
    CONCLUSION: It can be said that the use of ECMO in COVID-19 has been the trending topic recently and most of the studies are from countries in the ELSO Awards of Excellence list which indicates that the follow-up of ECMO in certain centers and teams can also be influencing the publications. This article can be a useful resource for clinicians, scientists, and students concerning global output for ECMO use in COVID-19.
    Keywords:  COVID-19; Extracorporeal membrane oxygenation; bibliometric analysis; trends
    DOI:  https://doi.org/10.1177/02676591221105405
  2. J Oral Biol Craniofac Res. 2022 Jul-Aug;12(4):12(4): 413-420
       Background: Identification of top cited articles aids in providing comprehensive and cumulative standardized quality work to research community. The present bibliometric study was aimed at identifying 100 top cited articles on Silver diamine fluoride, highlighting its landmark publications available in the current literature and aids in providing comprehensive and cumulative standardised quality work to research community.
    Methodology: Four major databases (Web of science, Pubmed, Scopus and Embase) were searched using search terms like 'silver fluoride' OR 'silver diamine fluoride' OR 'silverdiammine fluoride' OR 'diamine silver fluoride' OR 'diammine silver fluoride' OR silver ammonia fluoride AND dentistry. Selected publications were studied to tabulate information like journal, authors, year etc and contents of the publications were summarised. Variables such as journal name, first author, journal rank, citation count and average citations per year, authorship patterns, author's country of origin, most productive authors, journals and countries were identified. Additional outcome variables were SDF concentrations used, study designs adopted and SDF use like caries arrest/prevention/anti-hypersensitive agent and as an irrigant.
    Results: Among them maximum articles were clinical trials(n = 24) however systematic(n = 12), literature(n = 14) and narrative reviews(n = 12) had an equal share. The countries with the highest number of most-cited papers were China and USA. The most studied aspect was caries arrest. Journal of Dentistry and Journal of Dental Research had major publications among top cited papers.
    Conclusion: This particular review will prove to be a great source of information for research community worldwide and will aid in directing them towards relevant articles.
    Keywords:  Antimicrobial; Bibliometric analysis; Caries arrest; Silver diamine fluoride; Tooth; Top cited
    DOI:  https://doi.org/10.1016/j.jobcr.2022.04.008
  3. Curr Rheumatol Rev. 2022 May 27.
       BACKGROUND: Giant cell arteritis (GCA) carries significant risk of vascular and visual morbidity. Given its clinical importance, the 100 most frequently cited articles on GCA were systematically identified and bibliometrically analyzed.
    METHODS: All databases belonging to the Web of Science platform were searched for research articles with no restriction on publication date. The distribution of papers among journals, countries of origin, and publication type were evaluated. The correlations between year of publication with total number of citations and annual citation rate were also assessed.
    RESULTS: The top 100 articles on GCA were published between 1946 and 2018 and were cited a median (range) of 229 (153-1,751) times. The papers were published in 30 journals, including nine rheumatology journals (n=45), seven general medical journals (n=21), three ophthalmology journals (n=8), and eleven journals from other fields of research (n=26). Based on corresponding author affiliation, the articles originated from 13 countries, led by the US (n=55), Spain (n=12), and the UK (n=11). Clinical studies (n=73) and non-systematic reviews (n=11) were the most common publication types. The median (range) number of authors per article was 5 (1-44), and 73 individuals had more than one authorship. Year of publication was significantly correlated with annual citation rate (p<0.001) but not with total number of citations (p=0.487).
    CONCLUSION: This bibliometric analysis provides insight into the history and evolution of GCA research, highlighting some of the most influential contributions to the field. The latest landmark papers may not have been identified due to temporal constraints on citation accumulation.
    Keywords:  bibliometrics; citations; cranial arteritis; giant cell arteritis; publications; temporal arteritis
    DOI:  https://doi.org/10.2174/1573397118666220527143435
  4. Aesthet Surg J. 2022 May 29. pii: sjac137. [Epub ahead of print]
       BACKGROUND: Gender disparities are pervasive in academic plastic surgery. Previous research demonstrates articles authored by women receive fewer citations than those written by men, suggesting the presence of implicit gender bias.
    OBJECTIVES: We aim to describe current citation trends in plastic surgery literature and assess gender bias. We expected women to be cited less frequently than their male peers.
    METHODS: Articles published between 2017 and 2019 were collected from eight representative plastic surgery journals stratified by impact factor. Names of primary and senior authors of the fifty most cited articles per year per journal were collected and author gender was determined via online database and internet search. Median number of citations by primary and senior author gender were compared via Kruskal-Wallis test.
    RESULTS: Among 1167 articles, women wrote 27.3% as primary author and 18% as senior author. Women-authored articles were cited as often as those authored by men (p>0.05) across all journal tiers. Articles with a female primary and male senior author had significantly more citations than articles with a male primary author (p=0.038).
    CONCLUSIONS: No implicit gender bias was identified in citations trends, a finding unique to plastic surgery. Women primary authors are cited more often than male primary authors despite women comprising a small fraction of authorship overall. Additionally, variegated authorship pairings outperformed homogenous ones. Therefore, increasing gender diversity within plastic surgery academia remains critical.
    DOI:  https://doi.org/10.1093/asj/sjac137
  5. Aesthetic Plast Surg. 2022 May 31.
       BACKGROUND: Rhinoplasty is one of the most commonly performed aesthetic surgical procedures. The current study aimed to use bibliometric analysis to qualitatively and quantitatively evaluate rhinoplasty research and determine the research trends and hotspots in this field.
    METHODS: Publications on rhinoplasty research were extracted from the web of science core collection database. VOSviewer1.6.18 was used to analyze the co-authorship, co-occurrence, the citations of countries, institutions, authors, and hotspot keywords, and the journals in which the studies were published.
    RESULTS: On April 8, 2022, 11,130 records of rhinoplasty research published between 1945 and 2021 were collected. Most of the retrieved studies were original research articles (n = 8309, 74.65%), and 1950 (17.52%) papers were available in an open-access format. The annual publication output increased annually. Research groups in the USA were the main contributors and had a strong academic reputation in this field. University of California System was the institution with the greatest contribution (4.17%, with 464 publications). Plastic and Reconstructive Surgery (1248 publications, 11.21%) published the most research in this field and was also the most frequently co-cited journal (33,894 citations, total link strength [TLS]: 722,672). R. J. Rohrich (140 publications) was the most prolific author and the most frequently co-cited author (2562 citations, TLS: 56,624). The following rhinoplasty research hotspots were identified: cleft rhinoplasty, nasal reconstruction, nasal tip, revision rhinoplasty, septorhinoplasty, nasal prosthesis, hyaluronic acid, and preservation rhinoplasty.
    CONCLUSION: Our results provide a general overview of the major directions in rhinoplasty research. Preservation rhinoplasty, rib graft, nonsurgical rhinoplasty, hyaluronic acid, FACE-Q, fillers, and three-dimensional technology may be future research hotspots.
    LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  Bibliometric analysis; Nasal reconstruction; Rhinoplasty
    DOI:  https://doi.org/10.1007/s00266-022-02910-x
  6. Nitric Oxide. 2022 May 26. pii: S1089-8603(22)00053-2. [Epub ahead of print]
      Based on the Scopus record, Nitric Oxide journal (NOJ) has completed 25 years of publications. On 8th March 2022, the publication data was retrieved from the Scopus database and analyzed on VOSviewer and R-Studio (Bibliometrix R package/Biblioshiny). NOJ has published 1928 research documents majorly comprising of articles (1611/83.56%) and reviews (210/10.89%). The total citations and h-index were 56291 & 97, respectively. The per year (from 1997 to 2022) publications and citations are presented in this study. We tried to highlight some of the influential researchers, institutes, and countries. In all publications, 7450 authors have contributed with a collaboration index of 0.241. For all authors, we provided descriptive details about their total number of publications (NoP), total citations (TC), h-index, g-index, m-index, citations per paper (CPP), citation per year (CPY), HG Sqrt and Q2Index. Based on each indicator, we highlighted the top five scientists. The research publications (over time) of the top ten authors are also described. Furthermore, the collaboration network of authors is graphically presented. We also provided descriptive details about the most productive institutes. The highest number of documents are published by the University of Sao Paolo (n = 78), Brazil, while in-country sections, USA has the highest number of publications (n = 553) with 21739 citations and 69 h-index. In the same vein, for each era (five years) details about the top five countries are provided. In all publications (n = 1794), 34 European, 3 North American, 13 Asian, 10 South American, 5 Middle East, 8 African and 2 Asia Pacific countries have contributed. Numerical details about the collaboration links of all countries and the per-era contributions of the top ten countries are also provided. Based on the co-words analysis the per era research focus is graphically presented. Descriptive details about the major trends in publication in each era are also provided. We also manually analyzed 160 words that appeared more than thirty thousand (n = 30,000) times and tried to provide a broader overview of research publications. Based on Scopus record, the NOJ ranking is yearly improving and presently (2021-2022) it holds 14th and 17th positions in clinical biochemistry and physiology. The success could be attributed to all researchers, institutes, editors-in-chief, reviewers, editorial board & entire management.
    Keywords:  25 Years and Bibliometric analysis; Nitric oxide
    DOI:  https://doi.org/10.1016/j.niox.2022.05.003
  7. Front Mol Neurosci. 2022 ;15 905679
       Background: Pain is a common complication after stroke with a high incidence and mortality rate. Many studies in the field of pain after stroke have been published in various journals. However, bibliometric analysis in the domain of pain after stroke is still lacking. This study aimed to deliver a visual analysis to analyze the global trends in research on the comorbidity of pain after stroke in the last 12 years.
    Methods: The publications from the Web of Science (WoS) in the last 12 years (from 2010 to 2021) were collected and retrieved. CiteSpace software was used to analyze the relationship of publication year with countries, institutions, journals, authors, references, and keywords.
    Results: A total of 322 publications were included in the analysis. A continuous but unstable growth in the number of articles published on pain after stroke was observed over the last 12 years. The Peoples' R China (65), Chang Gung University (10), and Topic in Stroke Rehabilitation (16) were the country, institution, and journal with the highest number of publications, respectively. Analysis of keywords showed that shoulder pain after stroke and central post-stroke pain were the research development trends and focus in this research field.
    Conclusion: This study provides a visual analysis method for the trend and frontiers of pain research after stroke. In the future, large sample, randomized controlled trials are needed to identify the potential treatments and pathophysiology for pain after stroke.
    Keywords:  CiteSpace; bibliometric; pain; stroke; visual analysis
    DOI:  https://doi.org/10.3389/fnmol.2022.905679
  8. Aesthetic Plast Surg. 2022 Jun 02.
       BACKGROUND: Breast augmentation is one of the most demanded procedures in plastic surgery and one of the most commonly performed by plastic surgeons. However, a bibliometric analysis of breast augmentation has not been published in recent years. The current study aimed to use a bibliometric analysis to conduct a qualitative and quantitative evaluation of breast augmentation research and provide the research trends and hotspots in this field.
    METHODS: Publications on breast augmentation research were extracted from the Web of Science core collection database. VOSviewer 1.6.18 was used to assess co-authorship, co-occurrence, citation of countries, institutions, authors, and journals, as well as hotspot keywords.
    RESULTS: On February 8, 2022, 4637 records of breast augmentation research published from 1985 to 2021 were collected. The bulk of the retrieved studies were original research articles (n = 2235, 48.20%). A total of 1053 (22.71%) papers were open access. The annual publication output increased annually. The USA was the driving force in this field and had a strong academic reputation. The top-contributing institution was the University of Texas MD Anderson Cancer Center (2.37%, with 110 publications). Plastic and reconstructive surgery (998 publications, 21.52%) published the most research in this field and was also the most frequently co-cited journal (22,351 citations, total link strength (TLS): 409,301). Clemens MW (68 publications, 1.47%) was the most prolific author, and Spear SL (1456 citations, TLS: 27,231) was the most frequently co-cited author. The research hotspots included the following four aspects: safety and effectiveness of breast implants, implant-based breast reconstruction, breast cancer incidence after breast implantation, and breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL). The research trends were BIA-ALCL, implant-based breast reconstruction, BREAST-Q, acellular dermal matrix, capsular contracture, and autologous fat grafting.
    CONCLUSION: The present study provides a panoramic view of breast augmentation research in plastic and reconstructive surgery. This novel comprehensive bibliometric analysis can help researchers and nonresearchers alike to rapidly identify the potential partners, research hotspots, and research trends within their areas of interest.
    LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  Augmentation mammaplasty; Bibliometric analysis; Breast augmentation; Breast implants
    DOI:  https://doi.org/10.1007/s00266-022-02904-9
  9. Oral Maxillofac Surg. 2022 Jun 02.
       OBJECTIVES: An increasing number of articles are published each year. The aim of this is to provide a list of the 100 most cited articles on the subject of ameloblastoma.
    METHODS: A bibliographic search was performed on Google Scholar (GS), Microsoft Academic (MA), and Dimensions for ameloblastoma. A ranking was created in order of citation density. Graphical representations of keywords and authorship were created with VOSviewer. Statistical analysis was performed and only results with a 95% confidence interval were considered significant.
    RESULTS: A helpful list of top 100 articles was developed to help professionals in a variety of ways. Some curiosities are discussed about this scientometric analysis in ameloblastoma articles.
    CONCLUSIONS: A useful list of the top 100 most cited articles on ameloblastoma has been provided. Bibliometric and altmetric analysis using Google Scholar, Microsoft Academic, and Dimensions is a free and excellent tool, not only as a citation manager but also as a study reference.
    Keywords:  Ameloblastoma; Bibliometric analysis; Bibliometrics; Citation analysis; Citation classics; Scientometrics; Top-cited articles
    DOI:  https://doi.org/10.1007/s10006-022-01082-x
  10. Front Med (Lausanne). 2022 ;9 868040
      This study aimed to assess the research on medical Artificial intelligence (AI) related to sex/gender and explore global research trends over the past 20 years. We searched the Web of Science (WoS) for gender-related medical AI publications from 2001 to 2020. We extracted the bibliometric data and calculated the annual growth of publications, Specialization Index, and Category Normalized Citation Impact. We also analyzed the publication distributions by institution, author, WoS subject category, and journal. A total of 3,110 papers were included in the bibliometric analysis. The number of publications continuously increased over time, with a steep increase between 2016 and 2020. The United States of America and Harvard University were the country and institution that had the largest number of publications. Surgery and urology nephrology were the most common subject categories of WoS. The most occurred keywords were machine learning, classification, risk, outcomes, diagnosis, and surgery. Despite increased interest, gender-related research is still low in medical AI field and further research is needed.
    Keywords:  artificial intelligence; bibliometric analysis; gender; medical research; medicine
    DOI:  https://doi.org/10.3389/fmed.2022.868040
  11. World Neurosurg. 2022 May 27. pii: S1878-8750(22)00740-9. [Epub ahead of print]
       OBJECTIVE: To assess the Author Impact Factor (AIF) as a useful metric and as a complement to the h-index among neurosurgical researchers.
    METHODS: The 5-Year AIF and h-index were compared among three groups of researchers: (1) the 100 most prolific of all time within general neurosurgical journals ("Experienced"); (2) the 100 most prolific during the 2015-2019 period within general neurosurgical journals ("Trending Group"); and (3) the 100 Post Graduation Year 7 neurosurgical residents with the highest h-index ("Amateur").
    RESULTS: The Amateur group had a lower median h-index than the Experienced (6 vs 55; p<0.001) and Trending (6 vs 43; p<0.001) groups. The highest h-index of the Amateur group (24) was lower than the 1st quartile of the Experienced (46.25) and Trending (26.00) groups. The Amateur group had a lower median 5-Year AIF than the Experienced (2.15 vs 3.17; p<0.001) and Trending (2.15 vs 2.85; p=0.02) groups. Unlike the h-index, the gap between the 5-Year AIF distribution of the Amateur group and other groups was not profound. Although there was a positive correlation between the metrics in the three groups, they did not proxy for each other. For instance, while the h-index of some experienced authors that haven't published recently was high, their AIFs were zero. Also, some Amateur authors published very impactful articles and had a high 5-Year AIF. However, since their number of publications is inevitably low, their h-index were low.
    CONCLUSIONS: The AIF provides intuitive and complementary information to the h-index regarding the research output of neurosurgical authors.
    Keywords:  Author Impact Factor; Bibliometrics; Citation metrics; Neurosurgery; h-index
    DOI:  https://doi.org/10.1016/j.wneu.2022.05.100
  12. Trop Dis Travel Med Vaccines. 2022 Jun 01. 8(1): 14
       BACKGROUND: The neglected tropical diseases (NTDs) are endemic in several Arab countries. The purpose of the current study was to assess the contribution of researchers in Arab countries to the knowledge base on NTDs using bibliometric indicators.
    METHODS: Keywords related to all 20 NTDs were obtained from previously published bibliometric studies and were combined with the names of Arab countries listed as country affiliation. the search strategy was implemented in the Scopus database and bibliometric indicators were generated for the study period from 1971 to 2020 RESULTS: The search strategy generated 6542 documents; representing less than 4% of the global research in the field. Scientific research on NTDs from researchers in Arab countries (a) has experienced slow growth; (b) generated a relatively inadequate number of publications over the study period; (c) was disseminated mainly through journals in the field of parasitology or tropical medicine; (d) was contributed by researchers from the 22 Arab countries, but mainly by researchers from Egypt, Saudi Arabia, and Sudan; (e) has fragmented author networks with weak collaboration between active authors in the field; (f) was characterized by strong cross-country research collaboration with researchers in the US and the UK; (g) has focused on three main diseases, specifically, schistosomiasis, leishmaniasis, and onchocerciasis, and (h) showed less emphasis on soil-transmitted helminthiasis infections despite high prevalence.
    CONCLUSIONS: Arab countries cannot achieve the 2030 global agenda without control and elimination of prevalent NTDs. Researchers in Arab countries need to establish strong research networks to exchange expertise on all NTDs.
    Keywords:  Arab countries; Bibliometric analysis; Neglected tropical diseases
    DOI:  https://doi.org/10.1186/s40794-022-00173-7
  13. Front Surg. 2022 ;9 870781
       Background: Patellar instability is a common multifactorial disease in orthopedics, which seriously affects the quality of life. Because of the unified pathogeny, diagnosis and treatment, patellar instability has gradually attracted the interest of more scholars these years, resulting in an explosive growth in the research output. This study aims to summarize the knowledge structure and development trend in the field from the perspective of bibliometrics.
    Methods: The data of articles and reviews on patellar instability was extracted from the Web of Science database. The Microsoft Excel, R-bibliometrix, CiteSpace, VOSviewer, Pajek software are comprehensively used to scientifically analyze the data quantitatively and qualitatively.
    Results: Totally, 2,155 papers were identified, mainly from North America, Western Europe and East Asia. Until December 31, 2021, the United States has contributed the most articles (1,828) and the highest total citations (17,931). Hospital for Special Surgery and professor Andrew A Amis are the most prolific institutions and the most influential authors respectively. Through the analysis of citations and keywords based on a large number of literatures, "medial patellofemoral ligament construction", "tibial tubercle-trochlear groove (TT-TG) distance", "epidemiological prevalence", "multifactor analysis of etiology, clinical outcome and radiographic landmarks " were identified to be the most promising research directions.
    Conclusions: This is the first bibliometric study to comprehensively summarize the research trend and development of patellar instability. The result of our research provides the updated perspective for scholars to understand the key information in this field, and promote future research to a great extent.
    Keywords:  Bibliometrics; patellar dislocation; patellar instability; patellofemoral joint; visualized study
    DOI:  https://doi.org/10.3389/fsurg.2022.870781
  14. Environ Sci Pollut Res Int. 2022 Jun 02.
      Groundwater plays a pivotal role in sustaining the water needs of the population of South and Southeast Asia. However, long-term overexploitation and unsustainable practices have caused groundwater depletion, and deterioration in many parts of the region, further impacting human health and ecosystem services. Thus, understanding the current groundwater research activities and identifying the issues are crucial for improving future studies. This study conducted a bibliometric analysis to evaluate the groundwater-related literature available for South and Southeast Asia from the Scopus database for the last 50 years (1970-2020). Of the total, this study identified 7895 documents, representing 13% of the total global research productivity. India was the most productive country, followed by Pakistan and Malaysia. National Geophysical Research Institute, Anna University, and Indian Institute of Technology, Kharagpur, were the top three institutions with the highest number of groundwater-related publications. In international research collaboration, the USA and Japan were the two most collaborated countries with the South and Southeast Asian countries. Environmental science, earth and planetary sciences, and agricultural and biological sciences were the top three disciplines. The Environmental Earth Sciences journal published the highest number of groundwater-related publications in the study period. Research topic trends were observed through keyword analysis revealing increased outputs for groundwater quality, availability and suitability, recharge, and management. Our results provide valuable insights on groundwater issues that have received the most attention in South and Southeast Asia and identify the potential research topics and opportunities for researchers working in the groundwater domain.
    Keywords:  Bibliometrics; Groundwater; Keyword analysis; Scopus; South and Southeast Asia; VOSviewer
    DOI:  https://doi.org/10.1007/s11356-022-21163-4
  15. ANZ J Surg. 2022 May 30.
       BACKGROUND: women historically have been underrepresented in the field of academic publishing. This study aims to analyse ANZJS gender authorship trends and compare this to the proportion of women in surgery in Australia/NZ using RACS demographic data to provide parity context.
    METHODS: This is a bibliographic gender analysis of ANZJS publications from 2002 to 2021; articles were analysed using a web-based application classifying gender from names.
    RESULTS: There were exactly 7265 articles were analysed. Gender was predicted for 87% (6303/7265) first-, 89% (5847/6439) last- and 98% (323/329) editorial first-authors. There were 1269/6303 (20%) women first-authors, this increased from 14% to 27% (p = 0.001) over time. Eleven percent (654/5847) of last-authors were women, this proportion remained unchanged (p = 0.09). Eleven (3%) editorials were first-authored by women, with 3/329 (1%) as solo-author.
    CONCLUSION: Numbers of women authors remain low in ANZJS, although the percentage of women first-authors has increased over time. However, if being last-author serves as a measure of senior academic supervision, and, editorial authorship shows leadership in one's field, women authors in these positions, in ANZJS, represent a small minority.
    Keywords:  academic advancement; academic surgery; authorship; gender equity; women in surgery
    DOI:  https://doi.org/10.1111/ans.17822
  16. Orthop J Sports Med. 2022 May;10(5): 23259671221093074
       Background: The wide range of clinical applications and controversial scientific evidence associated with platelet-rich plasma (PRP) therapy in musculoskeletal medicine requires an examination of the most commonly cited studies within this field.
    Purpose: To identify the 50 most cited articles on PRP, assess their study design, and determine any correlations between the number of citations and level of evidence (LoE) or methodological quality.
    Study Design: Cross-sectional study.
    Methods: The Web of Science database was queried to identify the top 50 most cited articles on PRP in orthopaedic surgery. Bibliometric characteristics, number of citations, and LoE were recorded. Methodological quality was evaluated using the Modified Coleman Methodology Score (MCMS), Methodological Index for Non-randomized Studies (MINORS), and Minimum Information for Studies Evaluating Biologics in Orthopaedics (MIBO). The Pearson correlation coefficient and Spearman correlation coefficient (r S) were used to determine the degree of correlation between the number of citations or citation density and LoE, MCMS, MINORS score, and MIBO score. Student t tests were performed for 2-group comparisons.
    Results: The top 50 articles were published between 2005 and 2016 in 21 journals. The mean number of citations and citation density were 241 ± 94 (range, 151-625) and 23 ± 8, respectively, and the mean LoE was 2.44 ± 1.67, with 15 studies classified as LoE 1. The mean MCMS, MINORS score, and MIBO score were 66.9 ± 12.6, 16 ± 4.7, and 12.4 ± 3.7, respectively. No correlation was observed between the number of citations or citation density and LoE, MCMS, MINORS score, and MIBO score. A significant difference (P = .02) was noted in LoE in articles from the United States (3.56 ± 1.7) versus outside the United States (2 ± 1.5). Seven of the 8 in vivo studies were published between 2005 and 2010, whereas 19 of the 25 clinical outcome investigations were published between 2011 and 2016. Studies that were published more recently were found to significantly correlate with number of citations (r S = -0.38; P = .01), citation density (r S = 0.36; P = .01), and higher LoE (r S = 0.47; P = .01).
    Conclusion: The top 50 most cited articles on PRP consisted of high LoE and fair methodological quality. There was a temporal shift in research from in vivo animal studies toward investigations focused on clinical outcomes.
    Keywords:  PRP; level of evidence; methodological quality; orthobiologics; platelet-concentrated therapy; platelet-rich plasma
    DOI:  https://doi.org/10.1177/23259671221093074
  17. Front Neurol. 2022 ;13 871491
      Exosomes have received great attention for their diagnostic, therapeutic, and prognostic roles in the field of neuroscience over the past decade. This scientometric study aimed to quantitatively and qualitatively evaluate knowledge structure, hot topics, and research trends of studies about exosomes in the field of neuroscience using visualization tools. Web of Science Core collection databases were searched for relevant publications between 2005 and 2021. The Carrot2 online system, BICOMB, gCLUTO, and Ucinet software were utilized for key word analysis, and co-citations analyses were conducted in Citespace and VOSviewer. Altogether, 21 high-frequency key words were collected from 856 included articles, and 5 clusters were identified through biclustering analyses. The strategic diagram and social network analysis further determined research hotspots and trends. Co-citation analysis results revealed a few crucial works that contributed to the development of research on exosomes in the field of neuroscience. Moreover, the important sources that had contributed to the development of this field were identified. Our findings suggested that Alzheimer's disease-related research remained a hot topic in this field till now, and recent researchers had extended their scopes to more cognitive impairments. Importantly, researches related to exosomes in multiple sclerosis and Parkinson's disease were promising. While exosomes in acute central nervous system injury had not been sufficiently investigated, with continuous improvement in exosome-based delivery technology, this subject might make a breakthrough in terms of therapeutic innovations in the immediate future.
    Keywords:  Alzheimer's disease; Parkinson's disease; co-citation analysis; exosomes; field of neuroscience; key words analysis; multiple sclerosis; scientometrics
    DOI:  https://doi.org/10.3389/fneur.2022.871491
  18. J Cutan Aesthet Surg. 2022 Jan-Mar;15(1):15(1): 77-81
       Background: Dermatology is the science of the skin. In India, dermatology came into picture in the twentieth century. Today's dermatology practiced in India is the modern approach developed and established in western countries based on western medical theory, knowledge, experience, and results from study. Growth of dermatology field in India has progressed since two to three decades. This paper assesses the contributions made by India in the dermatology field by analyzing the total number of publications in top dermatological journals.
    Materials and Methods: SCImago Journal Rank indicator (2019) was used to search for top dermatology journals and publication metrics was recorded from respective journal websites. Simple statistics tools were used to determine the number of publications during this 20-year period.
    Results: From 1999 to 2019, there were 547 publications from India, in the top dermatologic journals. It was noted that, original research article contributes maximum number of documents (136). Journal of Dermatology had a maximum number of publications with 174 when compared to other journals. Postgraduate Institute of Medical Education and Research, Chandigarh' had a maximum number of publication (150).
    Conclusion: The last 20 years have seen a massive increase in the field of dermatology. Today, dermatology is a well-developed field in India. From 1999 to 2019, there is an increase in the trend of publications along with the collaborative publications in the top dermatologic journals. This show the encouraging trend in terms of publications from India in past 20 years.
    Keywords:  Dermatology; India; journals; publications
    DOI:  https://doi.org/10.4103/JCAS.JCAS_243_20
  19. Eur Rev Med Pharmacol Sci. 2022 May;pii: 28850. [Epub ahead of print]26(10): 3551-3561
       OBJECTIVE: This study aimed to analyze the current research status and trends of publications on relapsed/refractory Non-Hodgkin lymphoma (r/r NHL) using CiteSpace software and to know which centers and authors we should follow in the first place while doing research on r/r NHL.
    MATERIALS AND METHODS: The publications were retrieved from the Web of Science Core collection database, and CiteSpace (5.5.R5) software was used to analyze the authors, institutions, countries, and keywords.
    RESULTS: A total of 567 publications from 2009 to 2021 were retrieved, and the most fertile authors, institutions, nationalities and keywords in the field of r/r NHL were identified. Pier Luigi Zinzani team, Kensei Tobinai team, Andre Goy team, and Julie M. Vose team are recognized the main research teams in this field. USA makes the greatest contribution having research funds for r/r NHL. Key cluster areas of research include mantle cell lymphoma, pathway, lymphoma, relapse, pixantrone, Non-Hodgkin lymphoma, romidepsin, relapsed, T-cell lymphoma, and activated T cells. According to the keywords' timeline, the research trends of r/r NHL changed from bone marrow transplantation, radioimmunotherapy, chemotherapy to novel target drugs (like ibritumomab tiuxetan, inhibitor) and criteria EBM.
    CONCLUSIONS: The bibliometric study provides insights into hotspots and trends in the field of r/r NHL in the past 12 years. It serves us to extract useful information from complex data and provide information for clinicians and researchers.
    DOI:  https://doi.org/10.26355/eurrev_202205_28850
  20. Ann Med Surg (Lond). 2022 May;77 103542
       Background and objective: Adipose-derived mesenchymal stem cells (AdMSC) are multipotent adult mesenchymal cells isolated and cultured from the stromal vascular fraction derived from adipose tissue. The present study was conducted to analyze the global trends in AdMSC research using bibliometric and visual analysis tools.
    Methods: The literature search was done on February 13, 2022, using appropriate keywords and inclusion-exclusion criteria from the Scopus database. The extracted data were retrospectively analyzed and visualized using Bibliometrics and R packages and VOSviewer.
    Results: Preliminary analysis identified 1569 documents from the Scopus database published between 2005 and 2021. The average citations received per document was 26.51, whereas the average citations per year per document was 3.347. In addition, the selected documents had an h-index value of 90. China was the most productive country, whereas Seoul National University (South Korea) was identified as the most productive institute/university in AdMSC research. In addition, the National Natural Science Foundation of China funded the most research studies in AdMSC research.
    Conclusion: The findings from this study indicate a progressive increase in interest among the research community towards AdMSC, suggesting promising prospects in the coming years.
    Keywords:  AdMSC, Adipose-derived mesenchymal stem cells; Adipose tissue-derived mesenchymal stem cell; Adipose-derived mesenchymal stem cell; Bibliometric analysis; MSC, Mesenchymal stem cell; Mesenchymal stem cells; Research progress; Research trends; Scopus; WoS, Web of Science
    DOI:  https://doi.org/10.1016/j.amsu.2022.103542
  21. N Am Spine Soc J. 2022 Jun;10 100125
       Background: There are known classifications that describe thoracolumbar (TL) burst type injury but it is unclear which have the most influence on management. Our objective is to investigate the association of classification publications with the quantity and type of the most influential articles on TL burst fractures.
    Methods: Web of Science was searched, and exclusion and inclusion criteria were used to extract the top 100 cited articles on TL burst fractures. The effects on type, number, and other variables were separated into four eras as defined by four major classification publications.
    Results: 30 out of the top 100 articles represent level 1 or 2 evidence. The most influential journal was Spine, accounting for 35 articles and 4,537 citations. The highest number of articles (53) was published between the years 1995-2005, culminating with the Thoracolumbar Injury Severity Classification Score (TLICS) paper. After 2005, there was an increase in average citations per year. Following 2013, the number of highly influential articles decreased, and systematic reviews (SRs) became a larger proportion of the literature. There was a statistically significant increase in the level of 1 and 2 evidence articles with time until the publication of TLICS. The predictive value of time for higher levels of evidence was only seen in the pre-2005 years (AUC: 0.717, 95% CI 0.579-0.855, p = 0.002).
    Conclusions: In 1994, two articles marked the beginning of an era of highly influential TL burst fracture literature. The 2005 TLICS score was associated with a preceding increase in LOE and productivity. Following 2005, the literature saw a decrease in productivity and an increase in systematic review/meta-analysis (SR-MAs). These trends represent an increase in scholarly discussion that led to a systematic synthesis of the existing literature after publication of the 2005 TLICS article.
    Keywords:  AO classification; AUC, area under the curve; Bibliometric analysis; LOE, level of evidence; LSC, Load Sharing Classification; RCT, randomized controlled trial; ROC, receiver operating characteristic; SR, systematic review; SR-MA, systematic review with meta analysis; Systematic review; TL, thoracolumbar; TLICS; TLICS, Thoracolumbar Injury Severity Classification Score; Thoracolumbar burst
    DOI:  https://doi.org/10.1016/j.xnsj.2022.100125
  22. J Am Coll Radiol. 2022 May 27. pii: S1546-1440(22)00339-8. [Epub ahead of print]
       OBJECTIVE: To compare academic and demographic metrics among recipients of three major early career radiology, interventional radiology, and radiation oncology grants to National Institutes of Health (NIH) K awardees at the time the grants were awarded and then over the course of their careers.
    METHODS: Radiologists who received the RSNA Research Scholar Grant, General Electric Radiology Research Academic Fellowship (GERRAF), American Roentgen Ray Society (ARRS) Scholar Award, or NIH Career Development (K) Award before January 1, 2015, were included. Research metrics at time of grant award (eg, publications) and subsequent scholarly productivity (eg, academic rank, h-index, NIH funding) were recorded until April 2020. Wilcoxon ranked-sum, chi-square, logistic regression, and standard least-square regression were used for data analysis.
    RESULTS: There were 279 recipients: 48 K Award, 115 RSNA Research Scholar Grant, 36 ARRS, and 80 GERRAF. At the time of grant awarding, GERRAF recipients were less likely to have an MD-PhD degree (odds ratio [OR]: 0.36; P = .002) and were more likely to be women (OR: 1.55; P = .042) than K Award recipients. Similarly, recipients of the ARRS (OR: 2.87; P = .010) and GERRAF (OR: 3.19; P = .002) were more likely to have a master's degree. Academic rank, leadership positions, and R01 funding were significant predictors of h-index and total publications over time. Academic rank and the GERRAF were significant predictors of subsequent NIH funding duration but there were no significant predictors of NIH funding amount.
    CONCLUSIONS: Early career radiology awards, specifically the GERRAF, provide support for female and non-PhD investigators and result in comparable academic performance metrics to NIH K Award recipients.
    Keywords:  Early career grants; NIH; radiation oncology; radiology; research productivity
    DOI:  https://doi.org/10.1016/j.jacr.2022.04.003
  23. J Ophthalmol. 2022 ;2022 8195228
      This review is proposed to summarize the updates on COVID-19 and ophthalmology along with the bibliometric features of articles that have been published since the beginning of the COVID-19 outbreak. The databases, including PubMed, Scopus, and Web of Science, were searched using "Coronavirus," "COVID-19," "SARS-CoV-2," "pandemic," "ophthalmology," "ophthalmic," and "eye" keywords. All published articles except commentaries, errata, and corrigenda up to April 2021 were included. Titles and abstracts were screened, and ophthalmology-focused articles were collected. The bibliographic information of the articles, such as the name and country of the first author, type of study, date of publication, language, and journal name, were extracted. Included studies were assessed using the Joanna Briggs Institute (JBI) critical appraisal checklist. After systematic searching, 2,669 distinct articles were screened by title/abstract, and 1,174 ophthalmology-focused articles were selected to be reviewed. Ophthalmology-focused publications accounted for less than 0.5 percent of the total COVID-19-related articles. Most of the articles were published in the Indian Journal of Ophthalmology, and the main publication type was "original article." Almost 88% of the publications were in English. There was a decline in the publication rate during the initial months of 2021 compared with the middle and last months of 2020. Most of the publications were affiliated with the United States of America. However, Singapore and the United Kingdom were the countries with the highest number of publications after population adjustment. Furthermore, a comprehensive review on major topics including SARS-CoV-2 ocular tropism, ophthalmic manifestations, ocular complications due to COVID-19 treatment strategies, the pandemic effect on ophthalmology care and operations, myopia progression during the pandemic, and telemedicine was conducted.
    DOI:  https://doi.org/10.1155/2022/8195228
  24. J Clin Epidemiol. 2022 May 30. pii: S0895-4356(22)00138-X. [Epub ahead of print]
       OBJECTIVE: To evaluate the impact of co-publication on the citation of Cochrane evidence.
    STUDY DESIGN AND SETTING: This was a retrospective cohort study including Cochrane reviews published up to 31 December 2015 and their citing up to 11 July 2021, identified from the Web of Science Core Collection database.
    RESULTS: A total of 101 co-published and 202 non-co-published Cochrane reviews were included. The median for the total number of citations and the medians for the numbers of citations to the Cochrane review in the first, second, third and fifth years after publication in the co-published group were higher than those in the non-co-published group [71 (IQR: 37.5, 118.5) vs. 32.5 (13, 67); 1 (0, 3) vs. 0 (0, 1); 6 (3, 11.5) vs. 2 (1, 5); 8 (4, 15) vs. 3.5 (1, 8); 8 (4, 15) vs. 3 (1, 9), respectively, all p<0.001]. Co-publication of Cochrane reviews meant that 4 of 21 journals and 6 of 22 journals had a higher IF in the first and the second year after the co-publication than they would have had without the co-publication.
    CONCLUSION: Co-publication is associated with a higher citation frequency of Cochrane reviews and may increase the IF of the journal in which it is co-published. This facilitates broader application of Cochrane evidence and promotes its dissemination.
    Keywords:  Citation number; Co-publication; Cochrane reviews; Cohort study; Dissemination; Journal impact factor
    DOI:  https://doi.org/10.1016/j.jclinepi.2022.05.016
  25. Evid Based Complement Alternat Med. 2022 ;2022 4565069
      Osteoporosis has become a major public health problem and bisphosphates treatment for osteoporosis is a rapidly developing research field. Every year, plenty of studies devoted to the treatment of osteoporosis are published, giving clinicians a new perspective on bisphosphates treatment for osteoporosis. However, the quality of the scientific papers in this area is unclear. The aim of the present study was to characterize the 100 top-cited articles regarding bisphosphates treatment for osteoporosis. This analysis provides an accessible list for practitioners of endocrinology, pharmacy, epidemiology, imaging, surgery, and scientific research to identify the most frequently cited literature and better understand the future direction.
    DOI:  https://doi.org/10.1155/2022/4565069
  26. J Clin Epidemiol. 2022 May 27. pii: S0895-4356(22)00135-4. [Epub ahead of print]
    PRESS working group
       OBJECTIVE: To survey the citations of retracted non-Cochrane systematic reviews (SRs) in scientific literature .
    STUDY DESIGN AND SETTING: We searched the Web of Science and Google Scholar from their inception to 30 April 2020 to find the citations of 153 previously identified retracted non-Cochrane SRs. We calculated the numbers of citations before and after retraction separately. We also described how the citation addressed the retraction and how it was used in the article.
    RESULTS: A We identified 954 citations of 128 retracted SRs. The number of retracted SRs and citations reached the peak in 2014 and 2016, respectively, and the majority of the citations (n=580, 60.8%) were in articles published after the SR was retracted. The mean number of citation per retracted SRs was 7.5. 2.6 before and 4.5 after the publication of the retraction notice. Twenty-nine (5.0%) citations indicated the retraction of the SRs in the reference section. Nine of these citations supported the retracted SR's results, and 15 disagreed with them.
    CONCLUSION: Retracted SRs continue to be cited after the publication of the retraction notice. Standardized methods are needed to guide the management of retractions and avoid inappropriate citations of retracted articles.
    Keywords:  Citation; Meta-Analyses; Retraction; Systematic Reviews
    DOI:  https://doi.org/10.1016/j.jclinepi.2022.05.013
  27. Drug Discov Today. 2022 May 30. pii: S1359-6446(22)00214-8. [Epub ahead of print]
      Bacteriotherapy has proved to be a powerful tool in the fight against cancer. Herein, we used VOSviewer, CiteSpace, and Python to perform the first global bibliometric analysis of the literature from 2012 to 2021 on bacteria-mediated cancer therapy. Based on the results, East Asia and North America contributed the most publications to this research area. Additionally, the keyword analysis indicated that immunotherapy and nanoparticle (NP)-based drug delivery systems have long been popular topics in cancer bacteriotherapy, whereas the gut microbiota and probiotics are emerging research hotspots. This study provides crucial insights into the historical development of bacteria-mediated cancer therapy from 2012 to 2021, which will be helpful for scientists conducting further investigation into this promising field.
    Keywords:  Cancer; bacteria; bacteria-mediated cancer therapy; bibliometric analysis; cancer-bacteriotherapy
    DOI:  https://doi.org/10.1016/j.drudis.2022.05.023
  28. Work. 2022 May 25.
       BACKGROUND: Despite the prevalence of publications focusing on the trends of the studies on ergonomics, the information of the aging focused studies within these publications is limited.
    OBJECTIVE: This study aims to provide general information regarding the trends of the studies on ergonomics and aging by using bibliometric analysis techniques and to provide a general view regarding to the development of this field.
    METHODS: The bibliometric data of the publications on ergonomics and aging were retrieved from the WOS Database and analysed by using the Bibliometrix extension of the R Packet Programme. For the visualisation of the bibliometric data, the Vosviewer programme was used.
    RESULTS: Analysis results of the 405 papers published between the years of 1979 and 2020 show that main themes were digital human modelling, design for all, workplace ergonomics, transport and vehicle design, kitchen design, human factors, care and vision in old age.
    CONCLUSIONS: The content of the studies on ergonomics and aging changed from basic elements of ergonomic design for older people to the investigations about computer-aided applications and the effect of the developing technology. Therefore, it can be said that the studies on ergonomics and aging are changing parallel to the development of the technology.
    Keywords:  Ergonomics; aging; bibliometric; gerontology; old age
    DOI:  https://doi.org/10.3233/WOR-210112
  29. Front Cell Dev Biol. 2022 ;10 877079
      Radiotherapy, a popular cancer management procedure, negatively impacts reproductive health particularly by reducing the fertility potential. The purpose of this study was to analyze the research trend in radiotherapy associated with male infertility over the past 20 years (2000-May 2021). SCOPUS database was used to retrieve relevant scientometric data (publication per year, affiliation, journals, countries, type of document and area of research) for different subgenres of radiotherapy and male infertility. A total of 275 articles were published related to radiotherapy and male infertility, with the United States being the most dominant country in research output in this field. Radiotherapy and male infertility research have shown positive growth over the last two decades. In-depth analysis revealed that publications (n) related to radiotherapy and male infertility research mainly focused its impact on semen parameters (n = 155) and fertility preservation techniques (n = 169). Our scientometric results highlight a limited research focus on the field of radiotherapy and its impact on male reproductive hormones. Furthermore, a significant lack of research was noticed in the area of omics and male reproductive organs linked to radiotherapy. Substantial research is warranted to further decipher the effect of radiotherapy, at molecular level, leading to male infertility.
    Keywords:  fertility preservation; infertility; omics; radiotherapy; reproductive hormones; semen
    DOI:  https://doi.org/10.3389/fcell.2022.877079
  30. Nat Hum Behav. 2022 May 30.
      Citations and text analysis are both used to study the distribution and flow of ideas between researchers, fields and countries, but the resulting flows are rarely equal. We argue that the differences in these two flows capture a growing global inequality in the production of scientific knowledge. We offer a framework called 'citational lensing' to identify where citations should appear between countries but are absent given that what is embedded in their published abstract texts is highly similar. This framework also identifies where citations are overabundant given lower similarity. Our data come from nearly 20 million papers across nearly 35 years and 150 fields from the Microsoft Academic Graph. We find that scientific communities increasingly centre research from highly active countries while overlooking work from peripheral countries. This inequality is likely to pose substantial challenges to the growth of novel ideas.
    DOI:  https://doi.org/10.1038/s41562-022-01351-5
  31. J Trauma Acute Care Surg. 2022 Jun 01.
    EAST Research-Scholarship Committee
       INTRODUCTION: The EAST mission includes fostering research and providing career development opportunities. EAST has awarded for 20 years a Research Scholarship to a promising young investigator. The Research mentorship efforts were expanded 5 yrs ago with the INVEST-C Hack-a-thon. INVEST-C provides an intensive, short-term engagement to propel junior faculty toward establishing research independence. This study investigates the impact of these programs on academic productivity.
    METHODS: Pubmed records, NIH Reporter data, and SCOPUS h-index was acquired for all scholarship [SCH] awardees from 2002-2021 (n = 20) and all INVEST-C [INV] participants (2017-2020, n = 19). Current type of practice, total number of funding awards, and timing of first award were ascertained. INVEST-C participants were also surveyed on an annual basis to track their progress. Medians (IQR) are reported and compared (ANOVA).
    RESULTS: Median publications (PUB) of SCH awardees was 56 [IQR 33-88], h-index 16 (12-21), and 25% with > = 1 NIH grant since their SCH. Amongst the last 10 awardees with a minimum of 2 yrs from SCH, 40% have received a NIH award compared with a mean NIH funding rate of 18.5% over the same time period. For those remaining in academics (90% SCH), PUB were higher for those >5 yrs (66, 51-115) vs. <5 yrs from their SCH (33, 22-59, p = 0.05), but there was no difference in h-index (16, IQR 14-25, vs 15, 9-19, p = NS). Comparing the most recent 5 yrs of SCH to INV group, there was no difference in academic productivity as measured by total PUB (SCH 33, IQR 22-59 vs INV 34, IQR 18-44, p = 0.7) or h-index (INV 9, 5-14, p = 0.1). However, no attendee held research funding prior to INV, but 31.6% (6/19) have subsequently acquired > = 1 funding award (11 non-NIH, 1 NIH) in the short interval since participation.
    CONCLUSION: Investments in research activities have translated to significant extramural funding. Those in the last 5 yrs have been particularly fruitful with INV participants already achieving equal median academic productivity to SCH recipients.
    LEVEL OF EVIDENCE: Level III, Epidemiologic, Cohort.
    DOI:  https://doi.org/10.1097/TA.0000000000003714
  32. Ann Thorac Surg. 2022 May 25. pii: S0003-4975(22)00725-1. [Epub ahead of print]
       BACKGROUND: The objective of this work was to delineate career progression and research productivity of women practicing cardiothoracic surgery in the academic setting.
    METHODS: Cardiothoracic surgeons at the 79 accredited U.S. cardiothoracic surgery training programs in 2020 were included in this cross-sectional analysis. Data regarding sub-specialization, training, practice history, and publications were gathered from public sources including department websites, CTSNet, and Scopus.
    RESULTS: A total of 1065 surgeons (51.3% cardiac, 32.1% thoracic, 16.6% congenital) were identified. Women accounted for 10.6% (113) of the population (7.9% of cardiac, 15.5% of thoracic, 9.6% of congenital surgeons). The median number of cardiothoracic surgeons per institution was 12 [IQR 10-17], with a median of one woman [IQR 0-2]. Fifteen of 79 (19%) programs had zero women. Among women faculty, 5.3% were clinical instructors, 51.3% were assistant professors, 23.0% were associate professors, 16.8% were full professors, and 3.5% had unspecified titles (vs. 2.0%, 32.9%, 23.0%, 37.5%, and 4.6% among men, respectively, p<0.001). Women and men authored a comparable number of first-author (0.4 [0.0-1.3] vs. 0.5 [0.0-1.1], p=0.56) publications per year, but fewer last-author (0.1 [0.0-0.7] vs. 0.4 [0.0-1.3], p<0.0001) and total publications per year (2.7 [1.0-6.2] vs. 3.7 [1.3-7.8], p=0.05) than men. H-index was lower for women than for men overall (8.0 [3.0-15.0] vs. 15.0 [7.0-28.0], p<0.001), but was similar between men and women who had been practicing for 10-20 years.
    CONCLUSIONS: Gender disparities persist in academic cardiothoracic surgery. Efforts should be made to support women in achieving senior roles and academic productivity.
    DOI:  https://doi.org/10.1016/j.athoracsur.2022.04.057
  33. Ann Otol Rhinol Laryngol. 2022 Jun 03. 34894221100024
       OBJECTIVE: To compare NIH funding in the field of Otolaryngology to other medical and surgical specialties between 2009 and 2019.
    METHODS: Data was collected from the NIH RePORTER database on funding dollars received by each specialty from 2009 to 2019. Along with data on total active physicians per specialty using the Physician Specialty Data Book, comparisons were drawn between Otolaryngology and other medical and surgical specialties with regards to trends in total funding and NIH funding dollars per physician. The distributions of grant funding, within Otolaryngology from various NIH institutes among principal investigators, organizations, and subspecialties were further explored.
    RESULTS: There were 3810 grants (1147 unique projects) for a total of $1 276 198 555 funded by the NIH to Otolaryngology departments from 2009 to 2019. Statistically insignificant funding increases (P > .05) caused otolaryngology to fall from first to fourth in funding among studied specialties. The National Institute on Deafness and Other Communication Disorders funded 57% of all unique projects, and 57.2% of all unique NIH projects were otology related. Most projects were basic science related. The top 10 principal investigators obtained 22.3% of the total NIH funding for Otolaryngology. The top 3 organizations over the studied period comprised 26.55% of the total funding, generating a combined 729 grants. Among principal investigators, 63.0% had a PhD degree, 25.3% had an MD, and 9.6% had an MD/PhD.
    CONCLUSION AND RELEVANCE: NIH funding in Otolaryngology has remained stable and is highly concentrated among a small number of organizations, geographic regions, and principal investigators. Recent initiatives by academic communities have sought to address funding disparities by incorporating diversity and inclusion into clinician-scientist pipelines. We urge our colleagues to strive toward identification of the factors that contribute to successful acquisition of funding and implementation of a more conducive institutional infrastructure to produce research.
    Keywords:  NIH; National Institute of Health; otolaryngology; research comparison; research disparity; research ranking
    DOI:  https://doi.org/10.1177/00034894221100024
  34. Account Res. 2022 May 30.
      Retracted clinical trials may be influential in citing systematic reviews and clinical guidelines.We assessed the influence of 27 retracted trials on systematic reviews and clinical guidelines (citing publications), then alerted authors to these retractions. Citing publications were randomized to up to three emails to contact author with/without up to two co-authors, with/without the editor. After one year we assessed corrective action.We included 88 citing publications; 51% (45/88) had findings likely to change if the retracted trials were removed, 87% (39/45) likely substantially.51% (44/86) of contacted citing publications replied. Including three authors rather than the contact author alone was more likely to elicit a reply (P=0.03), but including the editor did not increase replies (P=0.66). Whether findings were judged likely to change, and the size of the likely change, had no effect on response rate or action taken. One year after emails were sent only nine publications had published notifications.Email alerts to authors and editors are inadequate to correct the impact of retracted publications in citing systematic reviews and guidelines. Changes to bibliographic and referencing systems, and submission processes are needed. Citing publications with retracted citations should be marked until authors resolve concerns.
    Keywords:  Publication integrity; clinical guideline; impact; retraction; systematic review
    DOI:  https://doi.org/10.1080/08989621.2022.2082290
  35. United European Gastroenterol J. 2022 Jun 03.
      
    Keywords:  impact factor; journalology; publishing; trainee editors
    DOI:  https://doi.org/10.1002/ueg2.12264
  36. J Therm Biol. 2022 May;pii: S0306-4565(22)00049-3. [Epub ahead of print]106 103234
      Climate action was among one of the main targets for the United Nation Sustainable Development Goals (i.e. UN SDG: 13), which is to "take urgent action to combat climate change and its impacts". The United Nations Framework Convention on Climate Change (UNFCCC) is also concurred to improve climate change's mitigation and adaptation strategies along with the SDG's goals. Thermal tolerance has been proposed as one of the possible adaptation strategies for animals affected by anthropogenic effects and excess heat from climate change. However, no scientometrics analysis of thermal tolerance research has been conducted to date. As a result, the goal of this study was to gather information from the literature to determine the current state of thermal tolerance, development trends, and current research. Researchers will be able to better understand the trends and development of the thematic research area of thermal tolerance by using scientometric analysis to generate data on thermal tolerance. For frequency, co-occurrence, co-citation, clustering, and burst analysis, CiteSpace software was used. The scientometric review of thermal tolerance studies from 1970 to 2021 (5243 studies) reveals significant increases in the size of the literature, the frequency of citations, and the hotspots investigated. Susan Lindquist and the Journal of Thermal Biology are the most influential authors and journals, respectively. The most common clusters related to the thematic area of thermal tolerance are oxygen consumption and heat shock protein, with climate change and temperature being one of the most popular keywords. We concluded that, along with the thriving field and climate change issues, thermal tolerance is becoming one of the future research interests. In addition, knowing the current trends and developments of thermal tolerance in aquatic species is important for various stakeholders.
    Keywords:  Acclimatization; Body size; Climate change; Oxygen consumption; Sustainable Development Goal; Temperature
    DOI:  https://doi.org/10.1016/j.jtherbio.2022.103234
  37. Ann Med Surg (Lond). 2022 May;77 103667
    Colombian Future Surgeons Collaborative Group
       Introduction: Global surgery has become the undisputed starting point for addressing a myriad of problems in surgery today. Therefore, it is necessary to constantly evaluate the scientific productivity in surgery, its behavior, validity and impact. In Latin America, specifically in Colombia, there are no studies that have analyzed this production.
    Methods: A retrospective cross-sectional bibliometric study was carried out, in which the Colombian Ministry of Science database was consulted with the validated results up to July 2021. In the search section for research groups, the key word "Surgery" was used, and all associated GrupLAC (platform where the information of the research groups can be found) and their registered products were reviewed.
    Results: 40 groups were included. Only 5 (12.5%) were registered in surgery as main line of research. The great majority of the groups were in the medium-low category, 50% in category C and 22.5% in category B. The vast majority of surgical groups are located in Bogotá (19; 47.5%). The first surgery group in the country was created in 1994 and the last one in 2017. In 27 years of surgical research, a total of 4121 registered scientific articles were found, 83 books, 713 book chapters, 2891 products associated with participation in scientific events, 1221 theses directed, and 1670 projects in colombian surgical research groups. There was evidence of a high rate of underreporting of data, due to duplication of products and incomplete registration of data.
    Conclusions: There is a high rate of underreporting of products and data in the GrupLAC of Colombian surgical research groups. Most of the production is located in the Andes region (Antioquia, Valle del Cauca and Bogotá), and is predominantly composed of scientific articles and products associated with participation in scientific events.
    Keywords:  Colombia; General surgery; Publishing; Research; Research group
    DOI:  https://doi.org/10.1016/j.amsu.2022.103667
  38. Res Vet Sci. 2022 May 23. pii: S0034-5288(22)00120-5. [Epub ahead of print]148 27-32
      Publication bias and the decreased publication of trials with negative or non-significant results is a well-recognized problem in human and veterinary medical publications. These biases may present an incomplete picture of evidence-based clinical care and negatively impact medical practices. The purpose of this study was to utilize a novel sentiment analysis tool as a quantitative measure for assessing clinical trial reporting trends in human and veterinary medical literature. Abstracts from 177,617 clinical trials in human medical journals and 8684 in veterinary medical journals published in the PubMed database from 1995 to 2020. Abstracts were analyzed using the GAN-BioBERT sentiment classifier for both general trends and percentage of neutral/negative publications. Sentiment was defined on a - 1 (highly negative) to 1 (highly positive) scale. Human-based clinical trial publications were less likely to feature positive findings (OR 0.87, P < 0.001) and more likely to include neutral findings (OR 1.18, P < 0.001) relative to veterinary clinical trials. No difference was found in reporting of negative sentiment trials (OR 1.007, P = 0.83). In both groups, the published sentiment of clinical trials increased over time. Using sentiment analysis to evaluate large publication datasets and compare publication trends within and between groups, this study is significant in its detection of significant publication differences between human and veterinary medicine clinical trials and a continued unbalanced positive sentiment in the published literature. The implications of this unbiased reporting have important clinical and research implications that require consideration.
    Keywords:  Clinical trial registries; Publication bias; Results reporting; Sentiment analysis
    DOI:  https://doi.org/10.1016/j.rvsc.2022.04.010
  39. Hum Genet. 2022 May 30.
      Angelman syndrome is a rare neurodevelopmental disorder caused by mutations affecting the chromosomal 15q11-13 region, either by contiguous gene deletions, imprinting defects, uniparental disomy, or mutations in the UBE3A gene itself. Phenotypic abnormalities are driven primarily, but not exclusively (especially in 15q11-13 deletion cases) by loss of expression of the maternally inherited UBE3A gene expression. The disorder was first described in 1965 by the English pediatrician Harry Angelman. Since that first description of three children with Angelman syndrome, there has been extensive research into the genetic, molecular and phenotypic aspects of the disorder. In the last decade, this has resulted in over 100 publications per year. Collectively, this research has led the field to a pivotal point in which restoring UBE3A function by genetic therapies is currently explored in several clinical trials. In this study, we employed a bibliometric approach to review and visualize the development of Angelman syndrome research over the last 50 years. We look into different parameters shaping the progress of the Angelman syndrome research field, including source of funding, publishing journals and international collaborations between research groups. Using a network approach, we map the focus of the research field and how that shifted over time. This overview helps understand the shift of research focus in the field and can provide a comprehensive handbook of Angelman syndrome research development.
    DOI:  https://doi.org/10.1007/s00439-022-02460-x
  40. Eur J Orthod. 2022 May 27. pii: cjac026. [Epub ahead of print]
       OBJECTIVES: To assess the representation of female scientists as speakers of blindly selected oral presentations or invited speakers in the latest European Orthodontic Society (EOS) conferences between 2015 and 2020. To examine the association with a number of study- and author-related characteristics.
    MATERIALS AND METHODS: Abstract books and programmes of the EOS conferences held between 2015 and 2020, were electronically searched to identify the gender of all speakers. The following predictor variables were assessed: year, continent of authorship, number of centres, number of authors involved, study design, study topic, and presentation as a WJB Houston Award nominee.
    RESULTS: A total of 312 oral presentations were recorded with almost even distribution of female/male gender. In the majority of oral presentations, a European-origin speaker affiliation was confirmed (208/312; 66.7%), with a relatively equal representation of women (P = 0.05). Seniority in authorship of oral presentations belonged to male scientists (209/312; 67%). Furthermore, a total of 84 invited speakers were identified, of which only 15 (17.9%) were female, indicating a substantial gender gap. No more than four women were invited to lecture annually, compared to a minimum of 10 male scientists. Overall, a significant difference was recorded for the odds of a female scientist to be invited as a speaker in the EOS conference (range of odds across years: 0.20-0.36), compared to the odds for conducting an oral presentation in the same context and timescale (range of odds across years: 0.75-1.45) (Mantel-Haenszel test for homogeneity, P-value < 0.001).
    LIMITATIONS: Findings were based solely on the annual orthodontic conference of the EOS, without further insights on national conferences, or identification of wide-range timescale effects.
    CONCLUSIONS AND IMPLICATIONS: Gender disparity related to invited speakers at the EOS 2015-20 annual conferences was unequivocally confirmed. Nevertheless, gender differences were not identified in oral presentations. Firm efforts to ensure female scientist's voice is equally represented are needed including a move from theory to practice.
    DOI:  https://doi.org/10.1093/ejo/cjac026
  41. JNCI Cancer Spectr. 2022 May 02. pii: pkac036. [Epub ahead of print]6(3):
      To explore persisting gender disparities across leadership roles in medicine, we examined factors associated with holding endowed chairs in US oncology divisions. In 2019, we identified 95 academic oncology divisions, using the Oncology Division Chiefs and Department Chairs listing in the American Society of Clinical Oncology myConnection forum. We collected public information on gender, degree, total National Institutes of Health funding as principal investigator, H-indices, publication and citation numbers, and graduation year and constructed a multivariable logistic regression model. All statistical tests were 2-sided. We identified 1087 oncology full professors. Of these, 287 (26.4%) held endowed chairs: 60 of 269 women (22.3%) vs 227 of 818 men (27.8%) (P = .08). On multivariable analysis, greater research productivity and National Institutes of Health funding were associated with having an endowed chair (P < .001), whereas gender was not (P = .45). Though sample size was limited, if gender differences are in fact smaller in certain subspecialties than other fields of internal medicine, insights might emerge to guide efforts to promote equity.
    DOI:  https://doi.org/10.1093/jncics/pkac036
  42. Forensic Sci Int Synerg. 2022 ;5 100269
      The large volume of information available within citation databases has become a challenge to manage and distil in all areas of research. In this study, a scientometric approach has been applied to fibres as an evidence type using information contained in Scopus and Web of Science. A comparison was also made with the references listed in the INTERPOL International Forensic Science Managers Symposium Science (IFSMS) reports (2004-2019) where only a limited number of documents were common with the citation databases, illustrating the value of the IFSMS reports. Finally, this study also highlights that data availability and location are generally omitted in publications. The forensic science community has an opportunity to change this culture and lead the way in making their data available, aligning with the ideals of fairness, openness and transparency of the underpinning data upon which scientific developments are based.
    DOI:  https://doi.org/10.1016/j.fsisyn.2022.100269
  43. Int J Radiat Oncol Biol Phys. 2022 May 30. pii: S0360-3016(22)00478-3. [Epub ahead of print]
       PURPOSE: Radiation Oncology (RO) societies which provide research grants from membership dues or charitable donations owe it to their funders to assess value-for-money, yet very little has been published on the outcomes of such grants. A previous Royal Australian and New Zealand College of Radiologists (RANZCR) survey confirmed significant academic impact from their RO grants. The purpose of this work was to update and broaden the survey using, to our knowledge for the first time in the RO literature, the "Payback Framework", a model employed extensively elsewhere in health research.
    METHODS AND MATERIALS: Between funding years 2010 and 2020, 58 grants were awarded to 41 individuals, median 1 per individual (range 1-4), median AUD$20k (US$14k) per grant (range AUD$5k-$26k). Five recipients of failed projects were excluded. The remaining 36 individuals, receiving 51 grants totaling AUD$940k (US$660k), were eligible for a voluntary on-line survey (SurveyMonkey) assessing project outcomes. Data collection and checking extended to 31 January 2022.
    RESULTS: The survey response rate was 100% (36/36). Objective academic outcomes attributable, at least in part, to the grants included 103 conference presentations, 59 publications, 21 prizes and 18 higher degrees. 27 consequential grants totaled AUD$6.4M (US$4.5M), a 6.8-fold return on investment. Broader impacts included perceived contributions to guideline development (53% of recipients), changes in clinical decision making (72%) or radiotherapy techniques (61%), enabling of subsequent research (56%), development of novel research tools (19%) and recruitment of research assistant(s) (19%). The three most important factors reported to contribute to project success were the RO grant (83%), networking (81%) and local infrastructure (81%). The grant program was rated very positively.
    CONCLUSIONS: This updated RANZCR survey has confirmed continuing significant academic output from its RO research grants but has also revealed broader benefits using the Payback Framework. We would encourage other RO societies to report their grant outcomes using a similar framework.
    Keywords:  Payback Framework; funding impact; radiation oncology; research grants; survey
    DOI:  https://doi.org/10.1016/j.ijrobp.2022.04.051