bims-evares Biomed News
on Evaluation of research
Issue of 2022–05–15
sixty-two papers selected by
Thomas Krichel, Open Library Society



  1. Front Mol Neurosci. 2022 ;15 854954
       Objective: To explore the development context, research hotspots and frontiers of Transcription factor EB (TFEB) from 1991 to 2021 by bibliometric analysis.
    Methods: Publications about TFEB research from 1991 to 2021 were retrieved from the Web of Science Core Collection (WoSCC). Excel 2007 was used to collect basic information, including publications, research areas. VOSviewer 1.6.17 was used to analyze co-authorship of countries, institutes and authors. Co-citation of cited authors, cited references were analyzed by CiteSpace V.5.8.R3. In addition, CiteSpace was used to analyze keywords cluster and forecast research frontiers.
    Results: A total of 1,059 literatures were retrieved, including 1,340 research institutes and 393 academic journals. The main area of research related to TFEB is biology (340), the most published country and institutes were the United States (487) and Baylor College of Medicine (70). Settembre C owned the highest co-citations (663). Trending keywords may indicate frontier topics, including "Alzheimer's disease," "Parkinson's disease," "(p21; q12)," "melanoma," "pancreatic cancer," "breast cancer," "calcineurin," "TFE3," "trehalose," and "curcumin."
    Conclusion: This research provides valuable information for the study of TFEB. Disease research focuses more on neurodegenerative diseases (NDs) and tumors. Trehalose and curcumin are novel agents acting on TFEB. Rap-TRPML1-Calcineurin-TFEB and TFE3 are increasing signal pathway researches, similarly, the molecular biological mechanism of TFEB needs further exploration.
    Keywords:  CiteSpace; VOSviewer; WoSCC; scientometric analysis; transcription factor EB
    DOI:  https://doi.org/10.3389/fnmol.2022.854954
  2. Indian J Orthop. 2022 May;56(5): 762-770
       Aim: We performed a bibliometric analysis of top 100 systematic reviews (SR) and meta-analyses (MA) in orthopaedic literature and also evaluated articles with maximum average citation per year, which were unable to make up in the present top 100 cited list, but may have a promising future in the world of citations.
    Methods: This bibliometric study was performed by searching Web of Science database according to a specific search strategy by two independent authors according to eligibility criteria of the studies. Articles with more than 100 citations were eligible for analysis and were evaluated for following parameters: number of citations, journal name, publication date and year, first author, the total number of authors, average citations per year, methodological design of the study, geographic origin and institute associated. Inter-rater reliability was evaluated using Kappa coefficient.
    Results: The number of citations ranged from 1073 to 198 with a total citation count of 30,589. Inter-rater reliability came to out in the good agreement (Kappa value-0.8). There was visible up-gradation of the research from the 2000 year till today. Spine journal had the maximum articles (26) followed by Journal of Bone and Joint Surgery-America (12 articles). The topics "Spine" and "Sports Medicine" were the most frequently cited topics with 41 and 20 articles, respectively. USA has the maximum articles in the top 100 cited SR and MA. Based on the maximum average citations per year, 34 old articles were replaced in the list with the latest articles that have a bright future ahead and can be predicted to be in the top 100 cited SR and MA of Orthopaedics soon.
    Conclusion: This study recognizes those articles that have contributed significantly to the growth of knowledge and influenced clinical practices in orthopaedics. We believe that this will facilitate and encourage researchers and clinicians in their future research.
    Supplementary Information: The online version contains supplementary material available at 10.1007/s43465-022-00604-9.
    Keywords:  Bibliometrics; Meta-analyses; Orthopaedics; Systematic review
    DOI:  https://doi.org/10.1007/s43465-022-00604-9
  3. Front Public Health. 2022 ;10 890773
       Background: Virtual simulation has been widely used in nursing education and nursing training. This study aims to characterize the publications in terms of countries, institutions, journals, authors, collaboration relationships, and analyze the trends of virtual simulation in nursing research.
    Methods: Publications regarding virtual simulation in nursing were retrieved from Web of Science core collection. Microsoft Excel 2010, VOSviewer were used to characterize the contributions of the authors, journals, institutions, and countries. The trends, hot-spots and knowledge network were analyzed by Citespace and VOSviewer.
    Results: We identified 677 papers between 1999 and 2021. The number of publications grew slowly until 2019, after that, it got a sharp increase in 2020 and 2021. The USA, Canada and Australia were three key contributors to this field. Centennial College and University of San Paulo, University of Ottawa and Ryerson University were top major institutions with a larger number of publications. Verkuyl M was the most productive and highest cited author. Clinical Simulation in Nursing, Nurse Education Today, Journal of Nursing Education were the three productive journals. The foundational themes of virtual simulation research in nursing are "virtual learning during COVID-19, clinical nursing care, education in nurse practitioners, education technology".
    Conclusion: Virtual simulation in nursing field has attracted considerable attention during COVID-19 pandemic. The research hotspot is gradually shifting from clinical nursing care to studies of nursing education using different virtual simulation technologies.
    Keywords:  Citespace; VOSviewer; bibliometric analysis; hot-spots; nursing; virtual simulation
    DOI:  https://doi.org/10.3389/fpubh.2022.890773
  4. Int Ophthalmol. 2022 May 12.
       PURPOSE: To explore the characteristics of the top 100 most-cited articles on keratoconus research.
    METHODS: The Web of Science database was searched to identify papers published from 1950 to 2020. A bibliometric analysis of the top 100 most-cited articles was conducted in the current study. The Kruskal-Wallis test was conducted to test the citation differences between basic research, clinical research, and reviews. The Spearman correlation analysis was used to investigate the association between citations and publication year. The VOSviewer software was used to create networks of co-authorship and keywords map.
    RESULTS: The median values of the number of citations, citations/year since publication, and citations since 2013 were 186.5, 13.90, and 11, respectively. A total of 79% of articles were clinical research. Reviews exhibited a higher value of citations/year since publication and citations since 2013 than basic research (all P < 0.05). The number of publications, total number of citations, citations/year since publication and citations since 2013 on the top 100 most-cited articles list increased with an increase in the publication year in three article types (all P < 0.05). The Journal of Cataract and Refractive Surgery had the highest number of articles. There were 37 articles from the USA. Rabinowitz, YS was the most-cited author with the greatest total link strength. Extensive collaboration existed among the main core nodes containing "cross-linking," "refractive surgery," and "penetrating keratoplasty."
    CONCLUSIONS: The present study focused on the comprehensive analysis of the top 100 most-cited articles on keratoconus research, providing insight into keratoconus research developments over the past decades.
    Keywords:  Bibliometric analysis; Citation; Keratoconus; Top 100 most-cited; VOSviewer
    DOI:  https://doi.org/10.1007/s10792-022-02334-1
  5. Front Med (Lausanne). 2022 ;9 850762
       Purpose: Herpes zoster infection, with its considerable burden to individuals and society, remains a challenge around the world. However, to the knowledge of the authors, little bibliometric quantitative or qualitative analysis has been carried out to evaluate herpes zoster research. This study aimed to use a bibliometric analysis to evaluate current publication trends and hotspots on herpes zoster research worldwide, in order to advance research in this field.
    Methods: Relevant publications from January 2012 to December 2021 were collected from the Web of Science Core Collection database. Citespace (V5.8.R3) was used to analyze the research points, including publication countries, institutions and authors, cited author, cited reference and their clustering, and keyword co-occurrence, and burst keyword to acquire research trends and hotspots.
    Results: A total of 9,259 publications were obtained, with a steady increase in the number of annual publications during the decade. Articles were the main type of publication. The United States is the leading country in this research, and the University of Colorado has the highest influence in this field. Oxman is the most representative author, with a main research interest in herpes zoster vaccines. The top five cited authors' publications focused on herpes zoster vaccines, molecular mechanisms, and postherpetic neuralgia. A co-citation map resulted 19 main clusters, and revealed that vaccines, postherpetic neuralgia, treatments, varicella zoster virus and its mechanisms, and epidemiology of herpes zoster were the current research focus after clustering co-cited publications. Human herpesviruses, antiviral prophylaxis, rheumatoid arthritis, recombinant zoster vaccine, varicella vaccination and postherpetic neuralgia were the top clusters after co-occurrence keywords analysis. Moreover, burst keywords detection showed that the subunit vaccine was the new hotspot in the field of herpes zoster.
    Conclusion: This bibliometric study defined the overall prospects in the field of herpes zoster and provided valuable instruction for the ongoing research. The keyword "subunit vaccine" indicated that a vaccine for herpes zoster prevention was the hotspot. Efforts to prevent varicella zoster virus infection will be essential to improve herpes zoster outcomes.
    Keywords:  bibliometric analysis; cited reference; citespace; herpes zoster; keywords co-occurrence and burst keywords
    DOI:  https://doi.org/10.3389/fmed.2022.850762
  6. Rheumatol Int. 2022 May 10.
      The extent, range, and nature of available research in the field of primary Sjögren's syndrome (pSS) have not been understood fully. This study aimed to map the literature available on pSS, and identify global hotspots and trends in the research. Papers on pSS published between 2004 and 2021 were searched from Web of Science Core Collection. The quantity and citations of publications, and the research hotspots and trends in the field of pSS were analyzed and presented visually by Microsoft Excel and Citespace software. A total of 3606 papers mainly from 526 institutions in 83 countries/regions were included for analysis. The number of publications presented an overall upward trend in the field of pSS from 2004 to 2021. The USA ranked first in the number of publications (n = 661), followed by China (n = 491), Italy (n = 405), France (n = 351), and Japan (n = 292). Moreover, seven of the top ten countries by the number of publications on pSS were from Europe. The University of Groningen (n = 661), Xavier Mariette (n = 95), and Clinical and Experimental Rheumatology (n = 184) were the most prolific affiliation, author, and journal, respectively. Vitali C (n = 2009) and Arthritis and Rheumatism (n = 3918) held the record for the most cited papers by an author and journal, respectively. At present, the hot keywords in the field of pSS include disease activity, ultrasonography, management, consensus, and data-driven. Lymphoid organization, clinical phenotypes outcome, salivary gland ultrasonography, and Toll-like receptor are the emerging research trends in pSS. Research on pSS is flourishing. Current research of pSS mainly focuses on disease activity, ultrasonography, and management. While, the emerging research trends in pSS are lymphoid organization, clinical phenotypes outcome, salivary gland ultrasonography, and Toll-like receptor.
    Keywords:  Bibliometric; Data visualization; Knowledge map; Research hotspot; Sjögren’s syndrome
    DOI:  https://doi.org/10.1007/s00296-022-05138-9
  7. Indian J Orthop. 2022 May;56(5): 785-796
       Purpose: The knowledge regarding meniscus has vastly evolved over the past few decades. The meniscus's intact, injured, and repaired status can affect other joint structures, i.e., ligaments, articular surfaces, and overall biomechanics of the knee joint. Due to available evidence's extensiveness, it is challenging to determine the most influential topics and the emerging trends in concurrent meniscus research. This study aims to identify the top fifty cited papers in meniscus research and concurrent knee issues and analyse their characteristics.
    Methods: A comprehensive search was conducted on the Thompson Reuters Web of Science database to prepare a list of top fifty cited articles that included original articles and review articles concerning meniscus. The included articles were analysed for the source journal, investigating institution, country of the corresponding author, year of publication, total citations, annual citation rate, and a qualitative review.
    Results: The search strategy resulted in 6768 original articles and 453 review articles. The top fifty cited articles were published from 1969 to 2014 and belonged to 14 journal sources. There were 43 original articles and seven review articles. The average citations per article were 417.4 and the average citations per paper per year were 22.6. Besides the meniscus, a general interest in the clinical assessment scores, anterior cruciate ligament, long-term osteoarthritis, and cartilage was observed.
    Conclusion: Most of the research concerning meniscus relates to the importance of meniscus preservation, the link between meniscus injuries and concomitant anterior cruciate ligament and chondral injuries, and its role in long-term gonarthrosis. The western countries have contributed the maximum to the top-cited evidence concerning meniscus. The meniscus repair and transplantation techniques have recently gained importance and need further research to qualify for the top-cited evidence.
    Keywords:  Bibliometric analysis; Knee joint; Meniscectomies; Meniscus; Tibial meniscus; Tibial meniscus tears
    DOI:  https://doi.org/10.1007/s43465-021-00592-2
  8. Int J Dent. 2022 ;2022 7678891
       Objective: To perform a bibliometric analysis of the scientific research on the development of vaccines against dental caries.
    Methods: An extraction of the scientific production published on the development of vaccines against dental caries between 2011 and 2020 was carried out from the Scopus database. Microsoft Excel was used for the elaboration of tables and SciVal for the bibliometric analysis of the data, which were divided into indicators of production, impact, and collaboration. Finally, VOSviewer was used for co-occurrence analysis of keywords and collaborative networks.
    Results: 106 studies were retrieved from the Scopus database, which were conducted on the development of dental caries vaccines within the years 2011-2020. Wuhan University, in China, was the university with the highest scientific production on the subject, with 4 publications. Regarding the most productive journals, the first place was occupied by the Journal of Dental Research with 7 publications. Regarding the most productive journals, the first place was occupied by the Journal of Dental Research with 7 publications. The highest percentage of the documents analyzed was in quartile 1 journals and in the national collaboration pattern.
    Conclusion: Most of the manuscripts regarding the development of vaccines against dental caries were published in China and in Q1 quartile journals. In addition, Yan Huimin, Yang Jingyi, Zhou Dihan, Yang Yi, Li Yuhong and Fan Mingwen were found to top the list of most productive authors. The Journal of Dental Research was also identified as the most productive and cited journal.
    DOI:  https://doi.org/10.1155/2022/7678891
  9. Int J Environ Res Public Health. 2022 Apr 20. pii: 5011. [Epub ahead of print]19(9):
      There are a wide variety of devices for the detection and diagnosis of caries from the initial stages. The purpose of this study was to perform a bibliometric study on research regarding caries diagnosis by identifying the contributing researchers, organizations, countries or regions, journals, and to provide an analysis of keyword co-occurrence and co-authorship networks. An advanced search was performed in Web of Science (WOS) Core Collection database, using the terms "caries diagno*" and "caries detect*" in the "topic" field, from 2013 to 2021. Bibliometric parameters were extracted using WOS's analyze results tools and VOSviewer software. A total of 816 documents were identified. Most of them, (61.3%) are included in "Dentistry Oral Surgery & Medicine" category within WOS. The largest scientific production on the subject is observed between 2018 and 2021, with a total of 344 records. The most productive author is Mendes FM, followed by Braga MM. The journal with the most articles published on caries diagnosis is Caries Research, with 55 articles (6.74%). The terms with the highest co-occurrence refer to the validity of diagnostic methods, tools or principles used in diagnosis or general aspects related to caries detection and diagnosis.
    Keywords:  bibliometric; caries detection; caries diagnosis; citations; scientometric analysis
    DOI:  https://doi.org/10.3390/ijerph19095011
  10. Asian J Psychiatr. 2022 May 04. pii: S1876-2018(22)00144-7. [Epub ahead of print]72 103146
       OBJECTIVES: to examine the global publication output on Obsessive Compulsive Disorder (OCD) during the last 20 years using bibliometric methods.
    METHODS: The quantitative and qualitative analysis of global publications was performed for all the publications in Scopus database by using "OCD, Obsessive Compulsive Disorder, other related disorders" as keyword in "Title" tag.
    RESULTS: 10,365 publications on OCD and related disorders were indexed in Scopus international database in the last 20 years and these publications were cited 241,962 times, averaging 23.34 citations per paper (CPP). About 24.91% share of global publication output received funding support and registered a CPP of 36.57. Among various countries, authors from USA, U.K., and Germany contributed the largest number of publications (3585, 965, and 836 publications), and publications arising from Netherlands (36.79 and 1.58), U.K. (32.65 and 1.40), and USA (32.43 and 1.39) registered the highest CPP and relative citation index (RCI). The organizations that produced the highest number of publications were Harvard Medical School, USA (487 papers), Massachusetts General Hospital, USA (454 papers), and King's College London, U.K. (297 papers). The authors who published highest number of papers were E.A. Storch (254 papers), D. Mataix-Cols (178 papers), and D.J. Stein (178 papers). The authors whose publications had highest CPP and RCI were B.D. Greenberg (USA) (73.76 and 3.16), and S.A. Rasmussen (USA) (63.36 and 2.71).
    CONCLUSIONS: This study reveals that majority of the research on OCD and related disorders is from the developed countries and compared to disorders like schizophrenia, OCD has received less research attention.
    Keywords:  Bibliometrics; Obsessive Compulsive Disorders; Publications; Scientometrics
    DOI:  https://doi.org/10.1016/j.ajp.2022.103146
  11. Curr Probl Cardiol. 2022 May 08. pii: S0146-2806(22)00140-2. [Epub ahead of print] 101243
       AIMS: Heart Failure with preserved Ejection Fraction (HFpEF) is a heterogeneous disease, which is becoming a worldwide menace. By retrieving the relevant literature of HFpEF from 2000 to 2021, qualitative and quantitative evaluations are carried out to visualize the scientific achievements in this field.
    METHODS: The data were from the Web of Science Core Collection database (WOSCC). The bibliometric tool-CiteSpace is used for scientific econometric analysis to understand the development of disciplines and research hotspots in this field.
    RESULTS: A total of 6318 HFpEF-related research papers were collected by WOSCC from 2000 to 2021, and the number of published papers and citations were in the rising stage. Fund-funded publications accounted for 80.4 percent of total publications, mainly at the national level, with the largest number being funded by the United States Department of Health and Public Services. The number of publications and centrality of the USA ranked first, indicating that the USA is mature in this research field and is in a leading position in the industry, which may benefit from the contributions of scientific research institutions such as Mayo Medical Center, Brigham Women's Hospital, Northwest University and Duke University. Low-income and middle-income countries lag far behind developed countries in terms of health care and scientific research and need to strengthen international cooperation.
    CONCLUSION: Bibliometric analysis shows that the main research directions of HFpEF are epidemiology, treatment, and comorbidity research of HFpEF and atrial fibrillation. Chronic microvascular inflammation is the latest research paradigm of HFpEF, especially phosphodiesterase 5 inhibitors.
    Keywords:  Bibliometrics; CiteSpace; Heart failure with preserved Ejection Fraction (HFpEF); Visualization
    DOI:  https://doi.org/10.1016/j.cpcardiol.2022.101243
  12. Laryngoscope. 2022 May 13.
       OBJECTIVE: To describe the academic impact and author characteristics of open-access journals in otolaryngology.
    METHODS: Original articles from three open-access (OTO Open, Laryngoscope Investigative Otolaryngology, and World Journal of Otorhinolaryngology) and three conventional subscription-based otolaryngology specific journals (Otolaryngology - Head & Neck Surgery, The Laryngoscope, JAMA Otolaryngology - Head & Neck Surgery) were assessed. Publication dates of articles from January 2017 to July 2020 were included. Google Scholar and Web of Science citation counts were recorded. H-indexes of first and last authors were included according to Google Scholar and Web of Science and analyzed.
    RESULTS: This analysis included 3284 articles. Articles published in open-access otolaryngology-specific journals had significantly fewer citations on average (6.8) than articles published in subscription-based journals (12.4, p < 0.0001). The last authors of articles published in subscription-based journals had significantly higher h-indexes (23.50) compared with the last authors of articles published in open-access journals (19.53, p < 0.0001). The first authors of articles published in open-access journals had similar h-indexes (10.26) as the first authors of articles published in subscription-based journals (10.33).
    CONCLUSIONS: Articles published in open-access journals in otolaryngology were cited significantly less than those published in subscription-based journals. The h-index of the last authors was significantly lower in open-access journals; however, the h-index of the first authors was similar between open-access and subscription-based journals. As measured by citations, open-access publications do not yet appear to have the impact of subscription-based publications.
    LEVEL OF EVIDENCE: N/A Laryngoscope, 2022.
    Keywords:  citation; h-index; open-access; otolaryngology
    DOI:  https://doi.org/10.1002/lary.30167
  13. Ann Transl Med. 2022 Apr;10(7): 401
       Background: Diabetes and periodontitis are common chronic diseases, and the pathogeneses of the 2 diseases both involve chronic inflammation. The presence of either of the 2 diseases increases the risk of the other, while the treatment of 1 can reduce the risk of the other. This study sought to summarize the current status of research in this field via a bibliometric analysis.
    Methods: The Science Citation Index Expanded (SCI-E) database was searched to retrieve relevant articles using the following search terms: "periodontitis" and "diabetes". Citespace software was used to analyze the search results, including the number of citations, the distribution of the countries, institutions, and journals that published the articles, the distribution of the authors, and the use of keywords in the articles.
    Results: A total of 2,151 articles, with 63,668 citations, were included in the analysis. The top 5 countries in terms of the number of published papers were the United States (US), China, Brazil, Japan, and the United Kingdom (UK), and the top 5 institutions in terms of the number of published papers were Columbia University, Sichuan University, the University of North Carolina, the University of Sao Paulo, and the University of Guarulhos. The top 5 authors in terms of the number of published papers were Loos, Park, Han, Wang, and Offenbacher. There was little cooperation overall. The top 3 journals in terms of the most published related articles were all periodontal disease-related journals. After periodontitis and diabetes, the most frequently used keywords were inflammation, and risk.
    Conclusions: More and more studies have been conducted on diabetes and periodontitis, and the current research mainly focuses on the treatment and management of these 2 diseases.
    Keywords:  Periodontitis; bibliometrics; diabetes; inflammation
    DOI:  https://doi.org/10.21037/atm-22-1067
  14. Paediatr Neonatal Pain. 2020 Jun;2(2): 22-32
      Retrospective evaluations of the historical role of previously published research are often fraught with subjective bias and misrepresentation, which leads to contested scientific claims. This paper investigates the historical roots of infant pain management using novel quantitative methods to identify the published literature and evaluate its relative importance. A bibliometric analysis named "reference publication year spectroscopy" (RPYS), was performed using the program CitedReferencesExplorer (CRExplorer) to avoid the subjectivity associated with comparative evaluations of individual research studies. Web of Science (WoS) search queries on infant-related synonyms, pain-related synonyms, and analgesia or anesthesia-related synonyms were combined using the Boolean operator "AND," to identify all publications related to pain management in infants. The RPYS analyses were based on 8697 papers in our publication set containing the citations for 86268 references. Selected cited publications were associated with peak citation years in 1951, 1954, 1957, 1965, 1987, 1990, 1997, 1999, and 2000. Subsequent analyses suggested that research on infant pain management made rapid progress during 1982-1992. Landmark publications were defined as those belonging to the top 10% of the most frequently referenced publications for longer than 25 years. Through this analysis, we identified and ranked 24 landmark publications to illustrate the historical background and early research on infant pain management. From the first-ever application of RPYS (an objective, reproducible approach to study the early history of any scholarly activity) to pain research, infant pain management appears rooted in the scientific rationale for neonatal pain perception, randomized trials of opioid anesthesia/analgesia, and studies describing the facial expressions and crying activity following heel-lance procedures in newborns.
    Keywords:  analgesia; anesthesia; bibliometrics; cited references analysis; infant‐newborn; nociception; pain; reference publication year spectroscopy (RPYS)
    DOI:  https://doi.org/10.1002/pne2.12035
  15. Curr Probl Cardiol. 2022 May 04. pii: S0146-2806(22)00110-4. [Epub ahead of print] 101213
       BACKGROUND: Chronic heart failure (CHF) is the terminal stage of a variety of heart diseases with higher morbidity and mortality. Although CHF has been studied for decades, the comprehensive analysis by bibliometrics has not been done. So, we analyzed the scientific outputs of global chronic heart failureresearches, explored the current research status and hotpots from 2009 to 2019.
    METHODS: Web of Science Core Collection (WOSCC) was the data source, and the data was retrieved on June 25, 2020, according to the set search strategy. Bibliometrics tools- CiteSpace V (Drexel university, Chaomei Chen) and VOS viewer (Leiden University, van Eck NJ)-were used for analyzing published literature and exploring research hotspots and frontier directions.
    RESULTS: A total of 21,484 articles were included, and the rate of published articles increased from 2009 to 2019 annually. United States of America (USA) was the leading country, Duke University was the leading institution, and Stefan D Anker was the most productive researcher in this field. The analysis of keywords showed that mortality, risk, outcomes, association, and dysfunction were the main hotpots and frontier directions of CHF.
    CONCLUSION: Bibliometric analysis of the outputs on CHF shows an overall view about the current status of the research on CHF. Clinical treatment and the associations among organs in the patients with CHF are the major research frontiers. However, further research and collaboration are still required worldwide. Our findings can help researchers grasp the research status of CHF and determine new directions for future researches as soon as possible.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; chronic heart failure
    DOI:  https://doi.org/10.1016/j.cpcardiol.2022.101213
  16. World Neurosurg. 2022 May 07. pii: S1878-8750(22)00591-5. [Epub ahead of print]
       BACKGROUND: The National Institute of Health (NIH) has developed a new metric, the Relative Citation Ratio (RCR), to assess the impact of research articles and compare academic productivity across different fields. Global surgery, obstetrics, trauma, and anesthesia (SOTA) are young and increasingly popular fields attracting researchers and funding. This study analyzes the RCR of global neurosurgery and compares it with other global SOTA specialties. The authors go on to discuss the implications for researchers, academic institutions, and aspiring global neurosurgeons.
    METHODS: Metadata were queried from the National Institute of Health (NIH) Relative Citation Ratio (RCR) website for twelve established global surgery specialties, including global neurosurgery. We performed descriptive and bivariable inferential analyses to evaluate differences in the number of total publications, median number of citations per year, and median RCR for each specialty for which data was available.
    RESULTS: Global surgery had the most publications (680 total articles, 20.61 articles/year). Global pediatric surgery had the highest median citations per year (2.00, IQR=0.63-3.50; P=0.048) and median relative citation ratio (1.36, IQR: 0.33-1.95; P=0.693). The median expected citations per year for all surgery, obstetrics, trauma, and anesthesia articles was 1.77.
    CONCLUSION: We observed a strong development of global neurosurgery and SOTA research. Overall, the use of Relative Citation Ratio will facilitate standardized inter-field and intra-field academic productivity comparisons. Based on the results presented in this study, we may assert that global neurosurgery is a viable career route for young and aspiring global neurosurgeons.
    Keywords:  global neurosurgery; global surgery; relative citation ratio
    DOI:  https://doi.org/10.1016/j.wneu.2022.05.003
  17. J Infect Dev Ctries. 2022 Apr 30. 16(4): 675-682
       INTRODUCTION: Leishmaniasis is a set of tropical diseases widely distributed throughout the world. Publications concerning different aspects of leishmaniasis have shown an increasing trend in recent years, especially in Brazil, where this disease has been under continuous expansion. The present study analyzes the data and assess trends in publications on leishmaniasis in Brazil and worldwide.
    METHODOLOGY: The bibliometric analysis was performed on the Scopus database, addressing data on scientific publications about leishmaniasis in the first nineteen years of the 21st century. The tendency of the annual number of publications was analyzed by mean of linear regression equations.
    RESULTS: The literature search identified 19.317 publications. Brazil was the country with the largest number of studies (24.88%). The annual growth rate for Brazilian publications was 4.66%, whereas worldwide publications grew 2.96%. The leading ten international authors contributed to 8.71% of the publications, whereas the ten principal Brazilian authors contributed to 4.31%. The largest collaboration network between authors was between Brazil and the United States. Oswaldo Cruz Foundation occupied the premier position in both worldwide and Brazilian ranking in number of publications. The international journal with the largest number of publications and SCImago Journal Rank indicator was PLOS Neglected Tropical Diseases. The Journal of Immunology had the highest H-index. Most of the research covered topics related to immunology and molecular biology.
    CONCLUSIONS: The data show relevant characteristics of the scientific production on leishmaniasis and demonstrate the fundamental role played by Brazil in the production of knowledge in this area of study.
    Keywords:  Brazil; Leishmaniasis; bibliometrics; information science
    DOI:  https://doi.org/10.3855/jidc.13064
  18. Front Res Metr Anal. 2022 ;7 869974
      The present study aimed to reveal the abundant tapestry of research on citrus waste and livestock feed, taking into account the recurring challenges posed by feed shortage and high price of conventional animal feed in livestock farming. In total, 565 articles were retrieved in a BibTeX format for analysis using bibliometric package in R studio. The retrieved data included, but not restricted to authors, citations, keywords, journals, and institutions. Published outputs on citrus waste and animal feed for livestock production obtained from Scopus and web of science (WOS) databases were used in this study. The field of citrus waste and livestock feed research experienced an increase in terms of research outputs with an annual growth of 10.20% during the study period. Based on the country level, Brazil was rated first with an aggregate sum of publications (n = 81), with China having a huge global academic influence with most top article citations (n = 1,338). The topmost authors' keywords commonly used in the studied research area were citrus pulp (n = 48), pectin (n = 26), performance (n = 22), and citrus (n = 33), which created a hint on associated studies on citrus waste and livestock feed. The present study provides a global trend to traverse the intellectual quandary on citrus waste and livestock feed research, and guidance for further studies in this field. It is essential to stress that the present study only dealt with core areas of citrus waste and livestock feed research, hence, it is anticipated that new empirical research and prospective solutions would afford new knowledge insight on citrus waste and livestock feed as new studies evolve.
    Keywords:  alternative feed resource; alternative resource; bibliometric evaluation; bibliometrics; citrus; feed; livestock; livestock production
    DOI:  https://doi.org/10.3389/frma.2022.869974
  19. Hand (N Y). 2022 May 13. 15589447221093672
       BACKGROUND: The purposes of this study were to analyze the trends in Oxford level of evidence (LOE), LOE of most-cited articles, and association between LOE and journal impact factor (IF) and SCImago Journal Rank (SJR) over a 10-year period (2009-2018) in 3 prominent hand surgery journals, specifically HAND, Journal of Hand Surgery (American Volume) (JHS), and Journal of Hand Surgery (European Volume) (JHSE).
    METHODS: All articles published from 2009 to 2018 in HAND, JHS, and JHSE were reviewed for assigned or available LOE. Data were pooled and analyzed for trends in LOE; relationship among IF, SJR, and LOE; and citation density.
    RESULTS: A total of 3921 total publications were tabulated from 2009 to 2018, with the majority of studies being level V (1700, 43%) and fewer studies being level I (146, 4%). Over the 10-year study period, there was no significant change in frequency of level I studies for any journal. HAND trended significantly toward higher LOE, JHS trended toward higher LOE, and JHSE trended toward decreased LOE without significance. Among all journals, the annual number of articles and the average LOE were independent significant predictors of IF and SJR. Statistically significant correlations were found between citation density and LOE for JHS and HAND.
    CONCLUSIONS: Higher quality evidence is becoming more prevalent in the hand surgery literature over the past 10 years. Annual articles, average LOE, and level I and II and level IV articles were significant predictors of increasing IF and SJR.
    Keywords:  SCImago Journal Rank; hand surgery; impact factor; level of evidence; top 10 most-cited
    DOI:  https://doi.org/10.1177/15589447221093672
  20. J Korean Med Sci. 2022 May 09. 37(18): e142
       BACKGROUND: Retraction is a process for correcting the literature and provides a barrier to the dissemination of publications that include major faults or false-misleading data. The aim of this study was to examine the characteristics of retracted articles in the biomedical field sourced from Turkey.
    METHODS: In this descriptive cross-sectional study, all retracted publications from Turkey on PubMed were listed without date restriction. Data covering the article title, authors, publication date, retraction date, time between publication and retraction dates (in months), journal, article type, country of the corresponding author, peer review timeline (in days), reason for retraction, and subject area of the retracted item were recorded. Citation data were obtained using the Scopus database. The altmetric attention scores of the articles were recorded.
    RESULTS: A total of 102 articles were listed and after the implementation of exclusion criteria, 86 articles were included for analysis. The first retracted article was published in 2000 (n = 1), while the most retracted articles were published in 2020 (n = 11). The median time lag between publication and retraction was 10.33 (0.73-144.06) months. The main factors causing retraction were plagiarism (n = 23), duplication (n = 22) and error (n = 17). The total number of citations was 695. A total of 224 citations were in the pre-retraction period and 471 citations were in the post-retraction period.
    CONCLUSION: The retracted article counts showed a rising trend over the years. The leading causes of retraction for articles from Turkey were plagiarism, duplication, and error. It was found that the articles continued to be cited after the retraction. Researchers in Turkey should be educated on retraction, particularly plagiarism and duplication. Strategies should be developed to prevent articles from being cited after retraction.
    Keywords:  Article; Duplication; Ethics; Plagiarism; Publication; Retraction; Turkey
    DOI:  https://doi.org/10.3346/jkms.2022.37.e142
  21. Clin Rheumatol. 2022 May 14.
       BACKGROUND: Sjögren's syndrome is an autoimmune disease with a complicated pathophysiology, and treatment strategies are in desperate need of improvement. In this research, we provide the literature topic trends and knowledge structure connected to Sjögren's syndrome from the perspective of bibliometrics for further research.
    METHODS: We acquired 3753 publications from the PubMed database and 3880 catalogs from the Web of Science Core Collection, with a time limit of 2010 to 2021 and the search term as "Sjögren's syndrome." Using the VOSviewer and bibliographic item co-occurrence matrix generator, we conducted cocited analysis, extracted major MeSH terms, generated matrices and performed biclustering analysis, visual matrix, drawn strategy diagram, and social network analysis.
    RESULTS: Through the clustering of the major MeSH terms, a total of five categories and 10 research topics were identified. Cocitation analysis suggests that diagnosis and clinical manifestations have been the main basis over the past 12 years and also are the mature content in the first quadrant of the strategy map. Ultrasonography, immunosuppressive agents and therapy, mechanism and therapeutic targets, and diagnostic autoantibodies are examples of the third quadrant, which wields great potential to progress. Genetic predisposition and psychology, in the fourth quadrant, need to be developed additionally. The subject keywords near the network's edge, such as "Salivary Glands, Minor/pathology," "Immunosuppressive Agents/therapeutic use," and "Autoantibodies/blood," are all growing research hotspots with much space, according to social network analysis.
    CONCLUSION: Through bibliometric analysis of the literature related to Sjögren's syndrome in the past 12 years, we obtained the knowledge basis, undeveloped topics, and emerging hotspots, which can suggest recommendations for future research. Key Points • We disclosed the topic trends and knowledge structure of Sjögren's syndrome literature over the past 12 years. • Clinical manifestations and diagnosis of Sjögren syndrome are included in mature and comprehensive studies, whereas ultrasonography, immunosuppressants and treatments, mechanisms and therapeutic targets, and diagnostic autoantibodies are studies with high potential for advancement. Additional research in genetics and psychology is needed. • We identified potential future research hotspots, including "Salivary Glands, Minor/pathology," "Immunosuppressive Agents/therapeutic use," and "Autoantibodies/blood."
    Keywords:  Biclustering analysis; Cocited analysis; Coword analysis; Hot research topics; Sjögren’s syndrome; Social network analysis; Strategic diagram
    DOI:  https://doi.org/10.1007/s10067-022-06196-x
  22. BMC Med Educ. 2022 May 10. 22(1): 356
       BACKGROUND: A rigorous faculty appointment and promotion (FAP) system is vital for the success of any academic institution. However, studies examining the FAP system in Asian universities are lacking. We surveyed the FAP policies of Taiwan's medical schools and identified an overreliance on the CJA score (manuscript Category, Journal quality, and Author order). The potential shortcomings of this metric and recommendations for refinement were discussed.
    METHODS: We obtained the FAP documents from all 12 medical schools in Taiwan, and analyzed their use of traditional versus non-traditional criteria for FAP according to a published methodology. The influence of the journal impact factor (JIF) on the FAP process was quantified by comparing its relative weight between papers with two extreme JIFs. To better understand the research impact and international standing of each school, we utilized the public bibliographic database to rank universities by the number of papers, and the proportions of papers within the top 10% or 50% citation.
    RESULTS: Compared with other countries, Taiwan's medical schools focus more on the quantifiable quality of the research, mostly using a "CJA" score that integrates the category, JIF or ranking, and authorship of a paper, with the JIF being the most influential factor. The CJA score for an article with a JIF of 20 can be up to three times the threshold for promotion to Assistant Professor. The emphasis on JIF is based on a presumed correlation between JIF and citation counts. However, our analysis shows that Taiwan's medical schools have lower-than-average citation counts despite a competitive rank in the number of publications.
    CONCLUSIONS: The JIF plays an unrivaled role in determining the outcome of FAP in Taiwan's medical schools, mostly via the CJA system. The questionable effectiveness of the current system in elevating the international standing of Taiwan's higher-education institutions calls for a re-examination of the FAP system. We recommend a reduction in the relative importance of CJA score in the FAP system, adopting more rigorous metrics such as the h-index for evaluating research quality, and supporting more research aimed at improving the FAP system.
    Keywords:  Faculty; Journal impact factor; Medical education; Research
    DOI:  https://doi.org/10.1186/s12909-022-03435-2
  23. J Patient Saf. 2022 May 04.
       BACKGROUND: Error reporting is vital for the prevention of medical errors. Despite the importance of error reporting, underreporting of medical errors is a common reality in many countries. Therefore, barriers to error reporting and reporting systems are a constantly evolving field of research. For this reason, studies on medical error reporting and reporting systems should be evaluated multidimensionally.
    AIM: The aim of this study is to evaluate the global research on medical error reporting and reporting systems through bibliometric analysis to obtain a structured macroscopic overview of the features and developments.
    METHODS: A bibliometric analysis of 1464 publications from 1970 to 2021 was performed to map the literature of medical error reporting and assess the structure of the scientific community.
    RESULTS: After 2000, the number of publications increased annually until a maximum of 2020 was reached. The International Journal for Quality in Health Care and the Journal of Patient Safety have been the most productive journals when it comes to publishing on the subject. Trend topics of keyword plus have changed over time. The United States (1399), England (580), and Australia (478) are the 3 nations with the highest number of publications. On the other hand, it is seen that the subject has yet to be discussed in a few developing or underdeveloped countries.
    CONCLUSIONS: This bibliometric analysis shows that the number of publications and authors and cross-country cooperation are low regarding error reporting. The low number of publications and the lack of cooperation, especially in developing countries, reveal the importance of global cooperation.
    DOI:  https://doi.org/10.1097/PTS.0000000000001025
  24. Front Endocrinol (Lausanne). 2022 ;13 845776
       Introduction: Thyroid nodules (TNs) are a common clinical condition. The probability of thyroid nodules being malignant is 7-15%. However, in recent decades, a number of publications on TNs have not been well summarized and discussed. The aim of this study was to summarize and sort out medical publications on TNs over the past 2 decades using a bibliometric method.
    Materials and Methods: Medical publications from January 1st, 2000, to November 1st, 2021, were searched in the Web of Science Core Collection database using the Medical Subject Heading (MeSH) term "thyroid nodule". Full associated data were downloaded, and detailed information was extracted using the bibliometric analysis platform VOSviewer.
    Results: A total of 8271 publications related to TNs from the last 2 decades were found and included in this study. An increasing trend was presented in the annual number of publications. The United States, China and Italy contributed the most publications. Carcinoma, management, ultrasound, and fine-needle aspiration were the most popular subjects in the field of TNs. The topics of the studies could be stratified into four clusters. The first cluster was using ultrasound to evaluate the nodules, including the thyroid imaging reporting and data system (TI-RADS), elastography and benign features. The second cluster was the fine-needle aspiration method, including the Bethesda system, cytology and BRAF mutations. The third cluster was the management of nodules, including radiofrequency and thermal ablation, surgery, and consensus statements. The last cluster was carcinoma, which is correlated with all three clusters described above. The preoperative diagnosis of cytologically indeterminate nodules was particularly highlighted in the top 10 most cited publications in recent years.
    Conclusion: How to diagnose thyroid nodules as malignant or benign, especially in cytologically indeterminate nodules, is still the most concerning topic in TN research. Although the fine-needle aspiration method and gene-expression classifiers show promising results, there is still a crucial need for translations from fundamental studies to clinical applications.
    Keywords:  FNA (fine needle aspiration); bibliometric; management; thyroid cancer; thyroid nodules
    DOI:  https://doi.org/10.3389/fendo.2022.845776
  25. NanoImpact. 2021 Jan;pii: S2452-0748(20)30072-0. [Epub ahead of print]21 100278
      The potential releases of nanoparticles (NPs) into soil medium have drawn considerable attention due to the increasing production and application of NPs worldwide. Understanding the interactions between NPs and plants is particularly important to assess the risks of NPs in the soil ecosystem. Although important knowledge has been gained about the NPs-plants interactions, current results of numerous published articles are still scattered. Therefore, this paper reviews the scientific progress in the NPs-plants interactions via a scientometric analysis to identify the main gaps and to provide future perspectives. Scientific documents on the interaction of nanoparticles and plant research during the period January 2000-July 2020 have been collected from Web of Science core collection and analyzed using CiteSpace. Overall, 9 scientometric indicators, i.e. literature quantity and growth trend, contributing countries, authors, institutions, keywords, cited journals, cited authors, and cited articles, are employed to understand the results retrieved from the 961 documents collected. The number of studies on nano-plant interaction research has been growing at an average annual rate of 56%. 71 countries and around 3380 authors have contributed to this field. Among the cited journals, Environmental Science and Technology stands out as the most-cited journal followed by Science of the Total Environment and Environmental Pollution, respectively. Moreover, the keyword citation burst, an indicator of the most active area of research or emerging trend, indicates that the beneficial side of nanoparticles and the trophic transfer require further exploration. This paper will be beneficial for fully understanding the salient research themes and the research trends of nano-plant interaction in future.
    Keywords:  Nanomaterials; Plant response; Scientometric study; Visualizations
    DOI:  https://doi.org/10.1016/j.impact.2020.100278
  26. J Surg Res. 2022 May 10. pii: S0022-4804(22)00231-1. [Epub ahead of print]277 335-341
       INTRODUCTION: Academic rank and metrics such as total publications (pubs) and H-index are indicators to measure academic achievement. This study aims to determine whether there are gender differences in academic productivity or faculty appointments among endocrine surgeons in the United States.
    METHODS: A database was generated from the American Association of Endocrine Surgeons (AAES) website. Community or academic practice was designated by institution affiliation and faculty appointment. Academic metrics, including pubs, H-index, and weighted-RCR (relative citation ratio), were obtained from public databases.
    RESULTS: A total of 258 AAES members were affiliated with an academic institution. The majority were men (58%). Overall, men in endocrine surgery had higher academic metrics: pubs (56.0 [26-134], 23.0 [11-56], P < 0.0001), H-index (19.0 [11-35], 9.0 [5-21], P < 0.0001), weighted-RCR (63.5 [22-193], 24.1 [8-74], P < 0.005) and rank (associate professor or professor, P < 0.0001). Subgroup analysis accounting for time in practice found no difference in total publications, weighted RCR, or faculty appointments between genders in practice for 0-5 y. However, among surgeons in practice for 6-10 y, men had higher academic metrics (pubs: 31.0 [16-79], 18.5 [9-33]; RCR: 46.0 [14-102], 13.3 [9-34]) and faculty appointments (all P < 0.05).
    CONCLUSIONS: There are gender disparities in academic productivity and faculty appointment among US endocrine surgeons. While junior faculty show no gender differences in most indicators of academic productivity or rank, men with 6-10 y in practice have higher average academic metrics and rank. Whether the absence of gender disparities among junior faculty is a sustainable reflection of recent efforts to encourage equal mentorship and professional opportunities or whether disparities will manifest as faculty progress remains to be determined.
    Keywords:  Academic surgery; Endocrine surgery; Gender disparities
    DOI:  https://doi.org/10.1016/j.jss.2022.04.045
  27. OTO Open. 2022 Apr-Jun;6(2):6(2): 2473974X221099499
       Objectives: The h-index is a measure of research output and contribution that shows strong correlation with academic promotion in medicine. The purpose of this article is to clearly explain how h-index scores are calculated and how otolaryngologists can effectively and advantageously use these scores for their career development.
    Data Sources: PubMed.
    Review Methods: We performed an up-to-date PubMed literature review describing the design of the h-index and how to use it effectively along with its role in academic medicine, including otolaryngology.
    Conclusions: H-index scores are used as a metric for scientific output that considers the number of publications and the number of times each is cited. Search engines can automatically calculate h-index scores for one's work. Studies also revealed significant positive correlations that the h-index has from fellowship involvement, which could be beneficial for career advancement in academic medicine.
    Implications for Practice: Aspiring academic otolaryngologists should create a research profile to link and calculate the h-index for publications, submit to well-read high-impact journals for increased viewership and citations, and expand on foundational and personal research topics. Future studies should evaluate faculty and resident awareness of h-indices in the otolaryngology department to see how we can further address any underlying barriers. Otolaryngologists with the knowledge and tools necessary to maximize h-index scores and produce high-quality research in modern-day medicine not only provide potential advantages in career development but also bring significant contribution to the field of otolaryngology and patient care.
    Keywords:  academic medicine; academic otolaryngology; fellowship training; h-index; research productivity; scholarly impact
    DOI:  https://doi.org/10.1177/2473974X221099499
  28. Int J Environ Res Public Health. 2022 May 03. pii: 5562. [Epub ahead of print]19(9):
      The application of resilience thinking to tourism destination research is a new perspective on sustainable tourism and has gradually become a popular research topic. Some literature has been conducted on tourism destination resilience, but there has not been a comprehensive review and analysis of the whole field. This study was based on the literature from 2000 to 2021 in the Web of Science core collection database. The collaboration analysis, literature co-citation analysis, keyword co-occurrence, burst detection analysis in CiteSpace, and qualitative analysis were adopted to conduct a holistic tourism destination resilience research review. The results indicated that the United States, Australia, China, and the United Kingdom were the primary countries involved in tourism destination resilience research. Five hot research themes were obtained. (1) concept and connotation of tourism destination resilience, (2) drivers of tourism destination resilience, (3) sustainable management framework and practices, (4) perception of tourism destination resilience, and (5) the resilience of the tourism community. Furthermore, four research gaps and future directions were proposed in this study, including the theoretical framework of tourism destination resilience, assessment of tourism destination resilience, sustainable management and resilience, and application of advanced technology in tourism destination resilience. This study assists researchers in understanding the development and future research directions in tourism destination resilience research.
    Keywords:  CiteSpace; bibliometric analysis; future research directions; research hotspots; tourism destination resilience
    DOI:  https://doi.org/10.3390/ijerph19095562
  29. Ecotoxicol Environ Saf. 2022 May 10. pii: S0147-6513(22)00466-3. [Epub ahead of print]238 113626
      Sustainable industrial development requires research on pollution control in industrial wastewater, particularly sulfate-rich wastewater, which poses a threat to the environment. This article differs from the previous sulfate wastewater treatment process and equipment review. Based on the quantitative analysis, this paper has determined some characteristics of the related literature on the pollution control technology of high-concentration sulfate wastewater to help researchers establish future research directions. From 1991-2020, the WoS database published 9473 articles related to high-concentration sulfate wastewater treatment technology. We used bibliometric analysis combined with social network analysis and s-curve technical analysis in this research. The United States was the first to start this type of research, Australia has insightful and instructive research articles in this area, and China is the most active in international cooperation. The keywords that appear most frequently in the dataset are degradation, adsorption, oxidation, reduction, and recovery. By S-curve fitting, it is known that biological treatment methods are closer to the maturity stage than physical and chemical treatment methods.
    Keywords:  Bibliometric analysis; Research progress; S-curve; Sulfate-rich wastewater; Wastewater treatment
    DOI:  https://doi.org/10.1016/j.ecoenv.2022.113626
  30. Int J Environ Res Public Health. 2022 Apr 19. pii: 4929. [Epub ahead of print]19(9):
      The journey of graduate students through academia can be a difficult road plagued with several roadblocks due to several intersectional factors. These difficulties often impact the students' mental health with severe consequences on their well-being and personal and academic achievements. There is a critical need for researchers to conduct studies in response to the positive mental well-being for this group of trainees, considering their peculiar role in the scholarly environment. This study aimed to explore the scientific research on the health and well-being of graduate students; typify the scientific landscape and development trajectory, cooperation networks, and fundamental research areas; and identify areas of needed research in this field. A bibliometric analysis of articles indexed in Scopus and published in the past decade (2012 to 2021) was undertaken. The results revealed that the research on graduate students' mental health and well-being has increased over the years, significantly in the past two years, probably owing to the incidence of the COVID-19 pandemic and concerns around remote learning. The highest number of publications was from the United Kingdom (U.K.) and United States (U.S.), while the organizational affiliations were mainly from universities. The most prominent source type of publications was journal articles. The result also shows a weak collaboration across countries and organizations. The study identifies other areas of useful research, collaboration, intervention strategies, and policy review.
    Keywords:  Ph.D. students; bibliometrics; graduate students; knowledge structure; mental health; well-being
    DOI:  https://doi.org/10.3390/ijerph19094929
  31. J Med Internet Res. 2022 May 11. 24(5): e36086
       BACKGROUND: Digital technology uses in cardiology have become a popular research focus in recent years. However, there has been no published bibliometric report that analyzed the corresponding academic literature in order to derive key publishing trends and characteristics of this scientific area.
    OBJECTIVE: We used a bibliometric approach to identify and analyze the academic literature on digital technology uses in cardiology, and to unveil popular research topics, key authors, institutions, countries, and journals. We further captured the cardiovascular conditions and diagnostic tools most commonly investigated within this field.
    METHODS: The Web of Science electronic database was queried to identify relevant papers on digital technology uses in cardiology. Publication and citation data were acquired directly from the database. Complete bibliographic data were exported to VOSviewer, a dedicated bibliometric software package, and related to the semantic content of titles, abstracts, and keywords. A term map was constructed for findings visualization.
    RESULTS: The analysis was based on data from 12,529 papers. Of the top 5 most productive institutions, 4 were based in the United States. The United States was the most productive country (4224/12,529, 33.7%), followed by United Kingdom (1136/12,529, 9.1%), Germany (1067/12,529, 8.5%), China (682/12,529, 5.4%), and Italy (622/12,529, 5.0%). Cardiovascular diseases that had been frequently investigated included hypertension (152/12,529, 1.2%), atrial fibrillation (122/12,529, 1.0%), atherosclerosis (116/12,529, 0.9%), heart failure (106/12,529, 0.8%), and arterial stiffness (80/12,529, 0.6%). Recurring modalities were electrocardiography (170/12,529, 1.4%), angiography (127/12,529, 1.0%), echocardiography (127/12,529, 1.0%), digital subtraction angiography (111/12,529, 0.9%), and photoplethysmography (80/12,529, 0.6%). For a literature subset on smartphone apps and wearable devices, the Journal of Medical Internet Research (20/632, 3.2%) and other JMIR portfolio journals (51/632, 8.0%) were the major publishing venues.
    CONCLUSIONS: Digital technology uses in cardiology target physicians, patients, and the general public. Their functions range from assisting diagnosis, recording cardiovascular parameters, and patient education, to teaching laypersons about cardiopulmonary resuscitation. This field already has had a great impact in health care, and we anticipate continued growth.
    Keywords:  atrial fibrillation; cardiac; cardiology; cardiopulmonary resuscitation; cardiovascular; electrocardiography; health application; heart; hypertension; photoplethysmography; wearable device, digital health, mHealth
    DOI:  https://doi.org/10.2196/36086
  32. Plast Reconstr Surg Glob Open. 2022 May;10(5): e4301
       Background: Lack of female and ethnically underrepresented in medicine (UIM) surgeons remains concerning in academic plastic surgery. One barrier to inclusion may be unequal opportunity to publish research. This study evaluates the extent of this challenge for plastic surgery trainees and identifies potential solutions.
    Methods: Data were collected on academic plastic surgeons' research productivity during training. Bivariate analysis compared publication measures between genders and race/ethnicities at different training stages (pre-residency/residency/clinical fellowship). Multivariate analysis determined training experiences independently associated with increased research productivity.
    Results: Overall, women had fewer total publications than men during training (8.89 versus 12.46, P = 0.0394). Total publications were similar between genders before and during residency (P > 0.05 for both) but lower for women during fellowship (1.32 versus 2.48, P = 0.0042). Women had a similar number of first-author publications during training (3.97 versus 5.24, P = 0.1030) but fewer middle-author publications (4.70 versus 6.81, P = 0.0405). UIM and non-UIM individuals had similar productivity at all training stages and authorship positions (P > 0.05 for all). Research fellowship completion was associated with increased total, first-, and middle-author training publications (P < 0.001 for all).
    Conclusions: Less research productivity for female plastic surgery trainees may reflect a disparity in opportunity to publish. Fewer middle-author publications could indicate challenges with network-building in a predominately male field. Despite comparable research productivity during training relative to non- UIM individuals, UIM individuals remain underrepresented in academic plastic surgery. Creating research fellowships for targeting underrepresented groups could help overcome these challenges.
    DOI:  https://doi.org/10.1097/GOX.0000000000004301
  33. Actas Dermosifiliogr. 2022 03;pii: S0001-7310(22)00134-X. [Epub ahead of print]113(3): 313-315
      
    DOI:  https://doi.org/10.1016/j.ad.2022.02.009
  34. Zhongguo Zhong Yao Za Zhi. 2022 Apr;47(8): 2228-2236
      This study aims to analyze the research on the prevention and treatment of cerebral small vessel diseases(CSVDs) with traditional Chinese medicine(TCM) based on knowledge map, and to preliminarily explore the research hotspots and trends. To be specific, articles on TCM treatment of CSVDs in CNKI, Wanfang, and VIP(from establishment to November 2021) were retrieved, followed by bibliometric analysis. Then CiteSpace 5.7 R4 and Gephi were employed for generation of maps on annual number of articles, author cooperation, institution cooperation, keyword co-occurrence, keyword clustering, and keyword emergence. A total of 106 eligible articles were screened out, and the annual number of articles presented a steady upward trend. A total of 277 authors were included in the author cooperation network, among whom CHEN Zhigang published the most articles. A total of 87 institutions were included in the institution cooperation network, among which Dongfang Hospital of Beijing University of Chinese Medicine showed the most frequent cooperation with other institutions. Keyword clustering showed that research on the TCM treatment of CSVDs mainly focused on five aspects: related disease research, neurological function deficits, disease nature and location in TCM, TCM treatment methods, and formulas. The prevention and treatment of CSVDs with TCM in China has been developing steadily in the past ten years, and TCM has unique advantages in the prevention and treatment of this disease. The knowledge maps vividly demonstrated the development and research hotspots and trends in this field. The result is expected to provide a reference for further research in this field.
    Keywords:  CiteSpace; Gephi; cerebral small vessel disease(CSVD); traditional Chinese medicine
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20220104.501
  35. Eur Heart J. 2022 May 14. 43(19): 1794-1798
      The association between the dissemination of scientific articles on Twitter and online visibility (as assessed by the Altmetric Score) is still controversial, and the impact on citation rates has never been rigorously addressed for cardiovascular medicine journals using a randomized design. The ESC Journals Study randomized 695 papers published in the ESC Journal Family (March 2018-May 2019) for promotion on Twitter or to a control arm (with no active tweeting from ESC channels) and aimed to assess whether Twitter promotion was associated with an increase in citation rates (primary endpoint) and of the Altmetric Score. This is the final analysis including 694 articles (one paper excluded due to retraction). After a median follow-up of 994 days (interquartile range: 936-1063 days), Twitter promotion of articles was associated with a 1.12 (95% confidence interval: 1.08-1.15) higher rate of citations, and this effect was independent of the type of article. Altmetric Attention Score and number of users tweeting were positive predictors for the number of citations. A social media strategy of Twitter promotion for cardiovascular medicine papers seems to be associated with increased online visibility and higher numbers of citations.
    Keywords:  Altmetrics; Cardiovascular articles; Citations; Randomized study; Social media; Twitter
    DOI:  https://doi.org/10.1093/eurheartj/ehac150
  36. NanoImpact. 2021 Apr;pii: S2452-0748(21)00025-2. [Epub ahead of print]22 100316
      Application of nanomaterials for the treatment of effluents originated from various industrial and non-industrial sources, has been rapidly developed in recent decades. In this situation, there is a need for conclusive studies to identify the current status of the knowledge in this field and to promote the commercialization of such technologies by providing recommendations for future studies. In the present manuscript, a scientometric assessment on the progress made in this field has been performed and the results have been organized and discussed in terms of science statistics, research hotspots and trends, as well as the relevant sustainability aspects. Based on a set of keywords, identified through a pre-literature analysis, a total of 6539 documents were retrieved from the Web of Science (WoS) database and analyzed to achieve the main goals of this study. The results demonstrate that the studies in this field have been initiated since the beginning of the 2000s but were mainly performed in lab and pilot scales. Also, China and Iran were identified as the most contributing countries in this scientific area in terms of the number of publications. Among various types of engineered nanomaterials (ENMs), there has been especial attention for the application of iron-based nanomaterials as well as carbonaceous structures (such as graphene oxide and biochar). Besides, there are not still strong collaborations formed among researchers in this area worldwide. Regarding the research hotspots, the synthesis of green and sustainable nanomaterials (e.g., biosynthesis approaches) has received attention in recent years. The results can also demonstrate that the most widely studied pathway for the removal of pollutants from (waste)waters involves the adsorption of the pollutants using ENMs. Treatment of contaminants of emerging concern (CECs) as well as exploring the mechanisms involved in the treatment of contaminated (waste)waters using ENMs and the possible by-products are considered the current trends in the literature. Regarding the sustainability aspects of ENMs for (waste)water treatment, the results achieved in this study calls for in-depth sustainability studies, which consider parameters such as economic, environmental, and social aspects of nanomaterials utilization for (waste)water treatment purposes, besides the technical parameters, to push transferring such technologies from lab and pilot scales to large and real-scale applications.
    Keywords:  Bibliometric analysis; Industrial effluents; Nanotechnology; Research trends
    DOI:  https://doi.org/10.1016/j.impact.2021.100316
  37. N Am Spine Soc J. 2022 Jun;10 100118
       Background: Excellent research in all fields, including spine surgery, exists in many different regions and languages. This study seeks to determine the relative number of spine related peer-reviewed publications throughout the world based on language.
    Methods: Peer-reviewed publications from the eleven most prolific languages in regard to both the number of peer-reviewed spine publications indexed in PubMed and total peer-reviewed publications from 1950-2020 were identified in PubMed.
    Results: 29,711,547 peer-reviewed publications were analyzed for the languages of interest with 870,404 (3.0%) of those being spine related peer-reviewed publications. Between 1988 and 2019, non-English language peer-reviewed publications decreased annually for both all peer-reviewed publications and spine related peer-reviewed publications by 44% and 36%, respectively. All medical and spine specific peer reviewed publications in English compared to non-English publications have increased by 7.22 and 6.35 times since 1988, respectively. While the ratio of non-English to English spine related publications decreased in all eleven countries, the percentage of the number of spine specific publications written in Chinese (462%), Portuguese (378%), and Spanish (88%) have increased by the listed percentages.
    Conclusion: While the proportion of peer-reviewed publications in the field of spine surgery written in English have increased over the past several decades, there are many non-English language peer-reviewed publications each year, particularly in Chinese. Although the rapid increase in the proportion of English spine related publications is beneficial to English speaking physicians and researchers, further research is necessary to understand the impact on non-English speaking physicians and researchers.
    DOI:  https://doi.org/10.1016/j.xnsj.2022.100118
  38. Int J Environ Res Public Health. 2022 May 09. pii: 5766. [Epub ahead of print]19(9):
      Global temperature change is related to the destiny of all mankind, and carbon mitigation, as well as greenhouse gases control, are key points. In order to explore the basic knowledge, research hotspots and trends in global carbon mitigation research, this paper, based on 15,304 carbon mitigation articles from Web of Science, from 1991 to 2021, conducts spatio-temporal distribution, country distribution, research hotspots and cooperation network analysis, and draws frontier knowledge graphs of carbon mitigation by using CiteSpace, Gephi and other scientific knowledge mapping and literature analysis software. The key scholars, important literature, main contribution institutions and countries/regions in the field of carbon mitigation research were extracted, and the research basis and evolution law were displayed. The study found that: (1) The research on carbon mitigation is increasing every year, which can be roughly divided into four stages: germination, low-speed development, medium-speed development and high-speed development. (2) The spatial distribution of carbon mitigation research is unbalanced, mainly showing a characteristic of "one super and many strong" centered on the United States. (3) The research hotspots of carbon mitigation have gradually evolved from phenomenon analysis, policy guidance, method exploration to mechanism improvement. Further research might focus on ocean carbon sink, carbon trading and carbon-negative technology.
    Keywords:  bibliometrics; carbon mitigation; hot spot analysis; scientific knowledge graphs; trend analysis
    DOI:  https://doi.org/10.3390/ijerph19095766
  39. Mar Pollut Bull. 2022 May 05. pii: S0025-326X(22)00394-0. [Epub ahead of print]179 113712
      Microplastic pollution in marine environment has been a growing public concern in recent years. This article analyzed the scientific literatures related to marine microplastics through a combination of social network analysis and bibliometrics. Researches related to microplastics have grown rapidly since 2011, with approximately two-thirds of the total number of articles published in the last three years. Researchers in United States and Europe have provided tremendous support, however, the efforts and progress of Chinese researchers cannot be ignored. Moreover, the international cooperation is getting closer, and related strategies are launched continuously. The results showed that Marine Pollution Bulletin is the most active journal. Through keyword analysis, we understand the development history and current hotspots of the whole microplastics researches, including ecological risks, interrelationship between microplastics and other pollutants, and detection methodology. Finally, some suggestions and perspectives for future microplastics research are provided.
    Keywords:  Bibliometric analysis; Ecological risks; Marine environment; Microplastics; VOSviewer
    DOI:  https://doi.org/10.1016/j.marpolbul.2022.113712
  40. J Informetr. 2022 May;16(2): 101295
      Based on publication data on coronavirus-related fields, this study applies a difference in differences approach to explore the evolution of gender inequalities before and during the COVID-19 pandemic by comparing the differences in the numbers and shares of authorships, leadership in publications, gender composition of collaboration, and scientific impacts. We find that, during the pandemic: (1) females' leadership in publications as the first author was negatively affected; (2) although both females and males published more papers relative to the pre-pandemic period, the gender gaps in the share of authorships have been strengthened due to the larger increase in males' authorships; (3) the share of publications by mixed-gender collaboration declined; (4) papers by teams in which females play a key role were less cited in the pre-pandemic period, and this citation disadvantage was exacerbated during the pandemic; and (5) gender inequalities regarding authorships and collaboration were enhanced in the initial stage of COVID-19, widened with the increasing severity of COVID-19, and returned to the pre-pandemic level in September 2020. This study shows that females' lower participation in teams as major contributors and less collaboration with their male colleagues also reflect their underrepresentation in science in the pandemic period. This investigation significantly deepens our understanding of how the pandemic influenced academia, based on which science policies and gender policy changes are proposed to mitigate the gender gaps.
    Keywords:  COVID-19; Gender inequality; Mixed-gender collaboration; Scientific collaboration; Scientific impacts
    DOI:  https://doi.org/10.1016/j.joi.2022.101295
  41. RSC Adv. 2022 May 05. 12(22): 14137-14153
      Silica aerogels are three-dimensional porous materials that were initially produced in 1931. During the past nearly 90 years, silica aerogels have been applied extensively in many fields. In order to grasp the progress of silica-based aerogels, we utilize bibliometrics and visualization methods to analyze the research hotspots and the application of this important field. Firstly, we collect all the publications on silica-based aerogels and then analyze their research trends and performances by a bibliometric method regarding publication year/citation, country/institute, journals, and keywords. Following this, the major research hotspots of this area with a focus on synthesis, mechanical property regulation, and the applications for thermal insulation, adsorption, and Cherenkov detector radiators are identified and reviewed. Finally, current challenges and directions in the future regarding silica-based aerogels are also proposed.
    DOI:  https://doi.org/10.1039/d2ra01511k
  42. J Cancer Policy. 2021 Dec;pii: S2213-5383(21)00044-8. [Epub ahead of print]30 100313
       BACKGROUND: The rapid growth in cancer research continues expanding the literature. Text mining approaches help make sense of large bodies of scientific literature and integrate the mounting data into the health care delivery system. Our objective is to generate a comprehensive understanding of the themes and trends in cancer research.
    METHODS: We employed a three-step text mining process of corpus generation and term-list creation and analysis, including latent semantic analysis for dimension reduction and factor analysis for topic identification to analyze 93,423 abstracts from the top 20 cancer/oncology journals for the period between 1999 and 2020.
    RESULTS: We identified 14 distinct topics in cancer literature. The results revealed the uptrend topics - including cell signaling (T-2), immunotherapy (T-3), clinical trials (T-5), disparities and epidemiology (T-7), cancer practice and policy (T-8), outcome research (T-9), and molecular therapeutics (T-10). - and downtrend topics such as cell death (T-1), early phase clinical trials (T-4), angiogenesis (T-6), cancer screening (T-12), and transplant (T-13). The topics of biomarkers(T-11) and cancer genetics(T-16) remained relatively stable. While the topics of angiogenesis (n = 10,490) and cell death (n = 10,258) included the highest number of abstracts, biomarkers (n = 3203), and cancer genetic (n = 4322) themes included the least number of articles. These findings suggest that despite having the lowest numbers of publications, certain topics such as cancer genetic (T-16) and biomarkers (T-11) have been exhibiting a stable trend and drawing a steady amount of attention from cancer researchers over the past 20 years.
    CONCLUSION: Findings of this study contribute explanatory insight about themes and trends in cancer research, which can help researchers and stakeholders to identify areas for future studies.
    POLICY SUMMARY STATEMENT: The findings indicate the increasing efforts to improve cancer practice and cancer care through policy efforts. Therefore, policymakers and other stakeholders may use the findings in prioritization and funding of specific topics.
    Keywords:  Cancer research; Oncology; Text mining; Themes; Topics; Trends
    DOI:  https://doi.org/10.1016/j.jcpo.2021.100313
  43. Environ Dev Sustain. 2022 Apr 30. 1-34
      In this paper, we reveal and systemize development trends in the scientific field of the circular economy (CE). Our results imply that academic research on the CE focuses heavily on theoretical conceptualizations and technological solutions. However, these advancements alone are unlikely to help prevent from ecological collapse. With this observation in mind, we explore the potential held by a more relational, action-based approach to support a faster and more efficient transition from the linear economy to the CE. A useful combination of several bibliometric techniques gave us valuable references for re-focusing this area of science to adopt action-oriented research where a group of stakeholders collaborates and co-creates solutions. An analysis of valuable action-oriented CE studies reveals that scholars focus on the techno-economic aspect, where they develop ways to create optimal circular material and energy flows and co-design processes for products/services, as well as the organizational aspect, where they study self-sustainable community networks and participatory governance. We identify three research streams that would benefit from such action-oriented research for a faster practical implementation: sustainable supply chains, waste management, and business model innovation. A practice-based agenda is proposed to stimulate the scientific community to conduct future research on a CE that better supports companies.
    Keywords:  Bibliometric analysis; Circular economy; Closed-loop system; Future research; Sustainability
    DOI:  https://doi.org/10.1007/s10668-022-02347-x
  44. Cureus. 2022 Apr;14(4): e23943
      The coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on the practice of medicine worldwide, particularly in anesthesiology. As the clinical realm has rapidly adjusted to the realities of the pandemic, anesthesiology literature has also changed significantly to reflect this. The purpose of this study was to characterize the effects the COVID-19 pandemic has had on anesthesiology literature. Specifically, it was hypothesized that the COVID-19-related literature in the anesthesiology community would gain more interest than non-COVID-19-related articles. A total of 15 anesthesiology-related journals with the highest impact factor in 2019, according to the Journal Citation Reports (JCR), were selected for data collection. An advanced PubMed search identified 5,722 COVID-19-related articles published by these journals in 2020. Next, articles with titles including "corona," "COVID," "COVID-19," "pandemic," "SARS," or "SARS-CoV-2" were selected for inclusion in the study, which resulted in 676 (12%) articles. A Kruskal-Wallis test was used to assess the Altmetric score, which is a weighted calculation of the attention an article receives online, for COVID-19 versus non-COVID-19 articles. Articles were then further characterized across multiple different variables, including country of origin, month published, type of article, and subspecialty of anesthesiology it pertained to. Of the 15 journals investigated, 676 (12%) articles of the 5,722 total articles published were found to be COVID-19-related material. The majority of the articles were found to be published in April (18%), May (19.5%), and June (14%). The majority of these articles were related either to general anesthesia (operating room anesthesiology that is not tied to a particular subspecialty fellowship track) (48%) or critical care (39%). By article type, most were determined to be editorial (71%) in nature, followed by original research articles (21%), of which most were cross-sectional (55%) studies. When compared with non-COVID-19-related articles, COVID-19-related articles had a significantly greater Altmetric score (29.518 versus 8.6333, p < 0.001). Of the COVID-19-related articles, original articles had the greatest Altmetric score, when compared to editorials and guidelines (54.794 versus 20.777 versus 40.643, p < 0.002). The response of the academic anesthesiology community to the COVID-19 pandemic was strong and timely, with a particularly strong focus on critical care anesthesia. The impact of the pandemic was strongly felt by the anesthesiology community, and their timely response served to guide our country and world through an incredibly challenging time. The pandemic highlighted the value of anesthesiologists worldwide, not only in the operating room setting but particularly as critical care physicians.
    Keywords:  acute respiratory distress syndrome (ards); altmetric attention score (aas); anesthesia literature; coronavirus disease 2019 (covid-19); severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
    DOI:  https://doi.org/10.7759/cureus.23943
  45. Minerva. 2022 Apr 30. 1-19
      In the 1990s, China created a research evaluation system based on publications indexed in the Science Citation Index (SCI) and on the Journal Impact Factor. Such system helped the country become the largest contributor to the scientific literature and increased the position of Chinese universities in international rankings. Although the system had been criticized by many because of its adverse effects, the policy reform for research evaluation crawled until the breakout of the COVID-19 pandemic, which accidently accelerates the process of policy reform. This paper highlights the background and principles of this reform, provides evidence of its effects, and discusses the implications for global science.
    Keywords:  China; Global science; Policy; Reform; Research evaluation
    DOI:  https://doi.org/10.1007/s11024-022-09468-7
  46. Plast Reconstr Surg Glob Open. 2022 May;10(5): e4300
       Background: The present study assesses training characteristics, scholastic achievements, and traditional career accomplishments of ethnically underrepresented in medicine (UIM) plastic and reconstructive surgery (PRS) faculty relative to non-UIM PRS faculty.
    Method: A cross-sectional analysis of core PRS faculty appointed to accredited United States residency training programs (n = 99) was performed.
    Results: Of the 949 US PRS faculty, a total of 51 (5.4%) were identified as UIM. Compared with non-UIM faculty, there were few differences when evaluating medical education, residency training, pursuit of advanced degrees, and attainment of subspecialty fellowship training. UIM faculty were more likely than non-UIM faculty to have graduated from a medical school outside the United States (25% versus 13%, P = 0.014). In addition, UIM faculty did not differ from non-UIM counterparts in traditional career accomplishments, including promotion to full professor, obtaining NIH funding, serving as program director, receiving an endowed professorship, appointment to a peer-reviewed editorial board, scholarly contributions (H-index and number of publications), and appointment to chief/chair of their division/department.
    Conclusions: The historical lack of ethnic diversity that comprise US academic PRS faculty persists. This study reveals that those UIM faculty who are able to obtain faculty appointments are equally successful in achieving scholastic success and traditional career accomplishments as their non-UIM counterparts. As we strive toward increasing representation of UIM physicians in academic plastic surgery, the field will benefit from efforts that promote a pipeline for underrepresented groups who traditionally face barriers to entry.
    DOI:  https://doi.org/10.1097/GOX.0000000000004300
  47. Eur Urol Focus. 2022 May 06. pii: S2405-4569(22)00104-3. [Epub ahead of print]
       BACKGROUND: Gender disparities in editorial board composition exist across a variety of surgical subspecialties.
    OBJECTIVE: To investigate temporal variation in gender representation on the editorial boards of urology journals and assess the relationship between editorial board composition and female authorship.
    DESIGN, SETTING, AND PARTICIPANTS: We analyzed female authorship and editorial board composition between 2002 and 2020 among eight high-impact urology journals. Female publication status was assessed using publication records retrieved from PubMed. Editorial board information was manually extracted and titles were grouped for comparison as Editor-in-Chief, mid-level editor, and consulting editors.
    OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Female representation across different editorial levels was analyzed via hierarchical logistic regression with additional terms to test for between-journal differences in overall representation and change over time. The relationship between representation on editorial boards and as publication authors was assessed at the journal level via correlation.
    RESULTS AND LIMITATIONS: Eight journals and 49 412 articles were analyzed. No female has held the title of Editor-in-Chief for any of these eight journals in 18 yr. Significant growth was seen for mid-level editors, whereas no growth was seen for consulting editors. Neurourology and Urodynamics and Journal of Sexual Medicine had significantly higher than average female editorial board representation (p < 0.05). Across the eight journals, there was a statistically significant correlation between the proportion of overall female authors and female editors (r = 0.93, 95% confidence interval 0.65-0.99). For all journals, the proportion of female contributing authors is greater than the proportion of female editorial board members.
    CONCLUSIONS: Women in urology represent a small but increasing presence as editorial board members. Clear differences exist between journals, potentially attributable to specialty-specific demographics. Despite increasing representation, no female has ever been appointed Editor-in-Chief for any of the eight journals evaluated. At the journal-specific level, a positive correlation was observed between female editorial staff and female authorship. Given the implication of both academic authorship and editorial board assignment on academic advancement, actionable changes are outlined to guide improvement in gender diversity at the journal level.
    PATIENT SUMMARY: Females are under-represented on the editorial boards for urology journals, although some roles have seen growth over time. Moreover, female editorial board membership is associated with representation of females among article authors. Gender disparities in both are noteworthy because they affect career paths and contribute to the gender gap in urology.
    Keywords:  Diversity; Gender; Practice patterns; Urology; Women
    DOI:  https://doi.org/10.1016/j.euf.2022.04.009
  48. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2022 Apr 20. 40(4): 279-282
      Objective: To analyze the literature of related research reports on occupational hearing loss (ONIHL) , study the characteristics of the subject and determine the research hotspots. Methods: In December 2020, PubMed database was searched by bibliometrics for ONIHL published in PubMed database from January 1971 to December 2020. Bicomb 2.03 software was used to extract the subject. The publication year, publication country, source magazine and subject words were summarized and analyzed. Results: A total of 1 473 papers were included in this study, and the number of papers was 66 from 1971 to 1980, and 628 from 2011 to 2020, an increase of nearly 10 times. The top three countries were the United States, China and Germany, with 31.5% (464/1473) , 11.5% (171/1473) and 6.2% (91/1473) ; The cross-sectional study was the most applied type; The top five words for 2011-2020: Mental Illness, polymorphism, cardiovascular disease, high frequency hearing impairment and standards and regulations. Conclusion: Susceptibility Genes, Psychological Disorders, Cardiovascular Diseases and Risk Assessment are hot areas in ONIHL at present. Researchers should focus on major fields and grasp future trends as a whole.
    Keywords:  Hearing loss; Literature measurement; Noise, occupational; Research hotspot
    DOI:  https://doi.org/10.3760/cma.j.cn121094-20210329-00174
  49. Int J Environ Res Public Health. 2022 May 05. pii: 5625. [Epub ahead of print]19(9):
      The prevention and treatment of cardiovascular disease (CVD) are necessary to improve patient quality of life and to reduce the burden of medical and other social problems. Reducing the impact of CVD through environmental intervention was hailed as the most economical approach and research into such interventions is becoming key. The purpose of this article is to summarize the research topics and developments in the field of the built environment and CVD between 2000 and 2021 using scientometric analysis. In total, 1304 records retrieved from the Web of Science core database were analyzed using CiteSpace software, and the results were displayed using knowledge mapping. The number of publications and conferences relating to the built environment and CVD showed an upward trend over the study period, with the United States taking the lead. Physical activity and the food environment were used as mediators and entry points to map the relationship between the built environment and CVD. Walkability, residence characteristics, the food environment, and greenness were key research topics. Research shifted over the period to incorporate quantitative analyses of subjective feelings while focusing on decreasing sedentary behavior. Understanding the variability in the built environment is critical to improving the generalizability of the findings presented in the individual studies. Inter-disciplinary and multi-disciplinary research is conducive to innovation and ensuring the integration of real environmental elements. This study provides an overview and valuable guidance for researchers relating to how the built environment impacts CVD.
    Keywords:  built environment; cardiovascular disease; food environment; physical activity; scientometric analysis; walkability
    DOI:  https://doi.org/10.3390/ijerph19095625
  50. FASEB J. 2022 May;36 Suppl 1
      In October 2021, the AD Scientific Index published a list of the Latin America Top 10.000 Scientists.This list was carefully elaborated to be a reference for the scientific performance and the added value of the scientific productivity of individual scientists. The total and last 5 years' values of the i10 index, h-index, and citation scores in Google Scholar were used. Individual scientists were classified by 12 subjects (Agriculture & Forestry, Arts, Design and Architecture, Business & Management, Economics & Econometrics, Education, Engineering & Technology, History, Philosophy, Theology, Law/Law and Legal Studies, Medical and Health Sciences, Natural Sciences, Social Sciences, and Others). Within these main subjects, a further classification included the authors' citation of their research field, such as organic chemistry, software architecture, anatomy, exercise physiology, neurosciences, and many others. Of the 10.000 scientists listed, a total of 7656 are Brazilian, most of them (2134) from the University of São Paulo. We searched the subject "Anatomy" on the list and found 33 mentions. From these, 29 are Brazilian scientists, 9 of them working with "plant anatomy" or related botanic fields, leaving a total of 20 names listed as working either on human or animal anatomy. We cross-checked these 20 names with the actual list of the Brazilian Society of Anatomy members and found that 18 listed scientists are members of the Brazilian Society of Anatomy (Sociedade Brasileira de Anatomia - SBA). Despite being little in number, Brazilian Anatomists have been expressively contributing to the Anatomical Sciences, having h-index above 26 and over 64,600 citations. The complete list with names, Institutions and field of interest will be presented.
    DOI:  https://doi.org/10.1096/fasebj.2022.36.S1.0R570
  51. Plast Reconstr Surg Glob Open. 2022 May;10(5): e4302
       Background: Academic advancement in plastic surgery necessitates creation of opportunities for rising faculty, which are pivotal for women in their efforts to close prominent gender gaps in higher ranks. We study positions of academic prestige that benefit from internal nomination as surrogates for opportunities afforded to men and women seeking leadership roles.
    Methods: We collected the following datapoints: authors of invited discussions published in Plastic and Reconstructive Surgery from 2010 to 2019; current editorial board members of representative plastic surgery journals; recipients of society-sponsored traveling fellowships; and directors of the American Board of Plastic Surgery. Public profiles for all authors and surgeons were referenced to confirm gender identification.
    Results: Seven-hundred ninety-seven plastic and reconstructive surgery discussions were included, 18% of which included female first or senior authorship. Seventy-one (9%) discussions listed a female senior author. Male and female senior authors were equally as likely to collaborate with a female first co-author (25% and 26%, respectively). Only 17% of invited authors contributed to 55% of discussion articles. Women occupied 19% of journal editorial board positions, though none were editors-in-chief. American Society of Reconstructive Microsurgery, American Society of Maxiliofacial Surgeons, American Society for Surgery of the Hand, and Plastic Surgery Foundation traveling fellowships were awarded to one (3%), four (7%), five (13%), and 141 (15%) female plastic surgeons, respectively. Women comprise 26% of directors of American Board of Plastic Surgery.
    Conclusions: Female representation in plastic surgery is rising, but it is not mirrored across appointed positions in academia. We should strive to support advancements that allow selected prestigious positions to more accurately reflect the gender distribution within the plastic surgery community.
    DOI:  https://doi.org/10.1097/GOX.0000000000004302
  52. BMC Res Notes. 2022 May 13. 15(1): 165
      Poor quality medical research causes serious harms by misleading healthcare professionals and policymakers, decreasing trust in science and medicine, and wasting public funds. Here we outline underlying problems including insufficient transparency, dysfunctional incentives, and reporting biases. We make the following recommendations to address these problems: Journals and funders should ensure authors fulfil their obligation to share detailed study protocols, analytical code, and (as far as possible) research data. Funders and journals should incentivise uptake of registered reports and establish funding pathways which integrate evaluation of funding proposals with initial peer review of registered reports. A mandatory national register of interests for all those who are involved in medical research in the UK should be established, with an expectation that individuals maintain the accuracy of their declarations and regularly update them. Funders and institutions should stop using metrics such as citations and journal's impact factor to assess research and researchers and instead evaluate based on quality, reproducibility, and societal value. Employers and non-academic training programmes for health professionals (clinicians hired for patient care, not to do research) should not select based on number of research publications. Promotions based on publication should be restricted to those hired to do research.
    Keywords:  Medical research; Reporting biases; Reproducibility; Research integrity; Research quality; Research waste
    DOI:  https://doi.org/10.1186/s13104-022-06050-y
  53. JMIR Public Health Surveill. 2022 May 10.
       BACKGROUND: Preprints are publicly available manuscripts posted to various servers that have not been peer-reviewed. Although preprints have existed since 1961, they have gained increased popularity during the COVID-19 pandemic due to the need for immediate, relevant information.
    OBJECTIVE: The aim of this study is to evaluate the publication rate and impact of preprints included in the CDC COVID-19 Science Update and assess the performance of the COVID-19 Science Update team in selecting impactful preprints.
    METHODS: All preprints in the first 100 editions (April 1, 2020 - July 30, 2021) of the Science Update were included in the study. Preprints that were not published were categorized as "unpublished preprints". Preprints that were subsequently published exist in two versions (in a peer-reviewed journal and on the original preprint server) which were analyzed separately and referred to as "peer-reviewed preprint" and "original preprint", respectively. Time-to-publish was the time interval between the date on which a preprint was first posted to the date on which it was first available as a peer-reviewed article. Impact was quantified by Altmetric Attention Score and citation count for all available manuscripts on August 6, 2021. Preprints were analyzed by publication status, rate, and time to publication.
    RESULTS: Among 275 preprints included in the CDC COVID-19 Science Update during the study period, most came from three servers: medRxiv (n=201), bioRxiv (n=41), and SSRN (n=25), with eight coming from other sources. More than half (152 of 275, 55.3%) were eventually published. The median time-to-publish was 2.31 months (IQR 1.38-3.73). When preprints posted in the last 2.31 months were excluded (to account for the time-to-publish), the publication rate was to 67.8%. Seventy-six journals published at least one preprint from the CDC COVID-19 Science Update and 18 journals published at least three. The median Altmetric Attention Score for unpublished preprints (n=123) was 146 (IQR 22-552) and median citation count of 2 (IQR 0-8); for original preprints (n=152) these values were 212 (IQR 22-1164) and 14 (IQR 2-40), respectively; for peer-review preprints, these values were 265 (IQR 29-1896) 19 (IQR 3-101), respectively.
    CONCLUSIONS: Prior studies of COVID-19 preprints found publication rates between 5.4% and 21.1%. Preprints included in the CDC COVID-19 Science Update were published at a higher rate than overall COVID-19 preprints, and those that were ultimately published were published within months and received higher attention scores than unpublished preprints. These findings indicate that the Science Update process for selecting preprints appears have done so with high fidelity in terms of their likelihood to be published and impactful. Incorporation of high-quality preprints into the CDC COVID-19 Science Update improves this activity's capacity to inform meaningful public health decision making.
    DOI:  https://doi.org/10.2196/35276
  54. Foods. 2022 Apr 29. pii: 1299. [Epub ahead of print]11(9):
      The relationship between food and human health drives the search for knowledge of food components that are related to these benefits. The scientific community shows a growing interest in the knowledge of the interactions between components of citrus fruits and probiotics to develop ways to improve the quality of the food produced. In this bibliometric review, a study of scientific publications is carried out on the potential of probiotics in citrus fermentation, addressing the importance and future trends of plant-based products in the functional food group as an alternative to the dairy market. The review process of the articles initially took place with a bibliometric analysis and was followed by a literature review. The Scopus database was used in the search for articles, carried out in May 2021. The use of foods as carriers of probiotics is an alternative that has been growing and the surveys evaluated show the desire to diversify the probiotics available on the market. In addition, it was observed that citrus fruits have great potential for the development of functional foods due to their high acceptability and possibilities of development and application in various products.
    Keywords:  citrus fruits; functional foods; health; probiotics
    DOI:  https://doi.org/10.3390/foods11091299
  55. Drug Discov Today. 2022 May 09. pii: S1359-6446(22)00172-6. [Epub ahead of print]
      University-industry collaborative research and development (UIC R&D) is generally seen as a driver of the pharmaceutical innovation process. Here, we perform a bibliometric review of UIC R&D practices over the past 30 years (1991-2020) by analyzing 800+ publications. At the strategic level of organizational cooperation patterns, the analysis shows that pharmaceutical UIC R&D mainly aims at strategic alliance formation, which gears toward universities and companies collaboratively exploring and commercializing technological breakthroughs. At the structural level of universities and companies investing in cooperation and aligning their activities, analytical results indicate that universities and companies organize themselves as interdependent entities in an open innovation ecosystem. At the cultural level of generally accepted collaboration norms and habits, analytical results show that university-company partnerships are becoming a rule rather than an exception. This study delves into a 30-year history of UIC R&D practices that support the pharmaceutical innovation process. It provides academics and practitioners with an insight into possible strategies for UIC R&D in the future and presents avenues for science, business and innovation research. Teaser: This paper describes the development of pharmaceutical university-industry collaborative research and development (UIC R&D) practices over the past 30 years (1991-2020), based on a bibliometric analysis of 800+ publications. It formulates advice for academics and business practitioners working in this field and provides an agenda for further research in this area.
    Keywords:  University–industry collaboration; big pharma; drug development; innovation ecosystem; strategic management
    DOI:  https://doi.org/10.1016/j.drudis.2022.05.001
  56. BMJ Open. 2022 May 12. 12(5): e061054
       OBJECTIVES: To investigate whether there is an association between women's representation as peer reviewers and editors of medical journals.
    METHODS: In this cross-sectional study, the gender of editors and peer reviewers of journals of the British Medical Journal Publishing Group (BMJ-PG) in 2020 was determined based on given names. Trends over time were analysed for the BMJ between 2009 and 2017.
    RESULTS: Overall, this study included 47 of the 74 journals in the BMJ-PG. Women accounted for 30.2% of the 42 539 peer reviewers, with marked variation from 8% to 50%. Women represented 33.4% of the 555 editors, including 19.2% of the 52 editors-in-chief. There was a moderate positive correlation between the percentage of women as editors and as reviewers (Spearman correlation coefficient 0.590; p<0.0001). The percentage of women as editors, excluding editors-in-chief, was higher when the editor-in-chief was a woman than a man (53.3% vs 29.2%, respectively; p<0.0001). Likewise, the percentage of women as peer reviewers was higher in journals that had a woman as editor-in-chief in comparison with a man (32.0% vs 26.4%, respectively; p<0.0001). There was a slight increase in the percentage of women as peer reviewers from 27.3% in 2009 to 29.7% in 2017 in the BMJ.
    CONCLUSIONS: Women account for less than one in three peer reviewers of medical journals. Women's representation as peer reviewers is higher in journals with higher percentage of women as editors or with a woman as editor-in-chief. It is, thus, imperative to address the persisting gender gap at all levels of the publishing system.
    Keywords:  general medicine (see internal medicine); medical education & training; medical ethics
    DOI:  https://doi.org/10.1136/bmjopen-2022-061054
  57. Arab J Urol. 2022 ;20(2): 81-87
       Objective: To conduct a scoping review examining the status of prostate cancer research in Arab countries and systematically map publications across the cancer care pathway. Prostate cancer incidence has been rising in the Arab world and tackling its increasing burden will require evidence-based policies.
    Methods: We searched Medline, PubMed and Scopus for peer-reviewed publications related to both our research topic and countries of interest by using controlled vocabulary and keywords. Search results were limited for the period between 2000 and 2020, screened for duplicates, and then included in our study based on pre-specified eligibility criteria. We used a structured data extraction form to extract information related to the article, its methodology, its cancer care pathway, funding status, and authorship.
    Results: A total of 4142 publications were retrieved from our search, of which 874 articles remained after applying eligibility criteria. Trends show a steady increase in prostate cancer research in the Arab world. Most studies were focussed on diagnosis and treatment, whereas a lack in studies concerning screening and prevention, as well as epidemiological data, was evident. Most studies were not funded and had no female author. Country gross domestic product and population were positively correlated with its research output. The USA had the highest number of corresponding authors. The majority of Arab-based studies did not involve collaborations with other countries. Most research conducted was basic or clinical studies with a low level of evidence.
    Conclusion: Our present review identified significant gaps and limitations in prostate cancer research in Arab countries. Priority areas for research investment have also been highlighted as a first step towards context-specific health policies.
    Abbreviations: ASR: age-standardised rate; COVID-19: coronavirus disease 2019; GDP: gross domestic product; HDI: Human Development Index; KSA: Kingdom of Saudi Arabia; UAE: United Arab Emirates.
    Keywords:  Arab region; Prostate cancer; bibliometrics; oncology; screening; urology
    DOI:  https://doi.org/10.1080/2090598X.2021.2024984
  58. J Am Acad Dermatol. 2022 May 09. pii: S0190-9622(22)00786-1. [Epub ahead of print]
      
    Keywords:  authorship; clinical trials; dermatology; disparity; gender; research
    DOI:  https://doi.org/10.1016/j.jaad.2022.05.002
  59. J Clin Pathol. 2022 May 11. pii: jclinpath-2021-208051. [Epub ahead of print]
      
    Keywords:  EDUCATION; QUALITY CONTROL; STATISTICS
    DOI:  https://doi.org/10.1136/jclinpath-2021-208051
  60. PLoS One. 2022 ;17(5): e0266132
    COVID-SHINE group
      The COVID-19 pandemic has been testing countries' capacities and scientific preparedness to actively respond and collaborate on a common global threat. It has also heightened awareness of the urgent need to empirically describe and analyze health inequalities to be able to act effectively. In turn, this raises several important questions that need answering: What is known about the rapidly emerging COVID-19 inequalities research field? Which countries and world regions have been able to rapidly produce research on this topic? What research patterns and trends have emerged, and how to these compared to the (pre-COVID-19) global health inequalities research field? Which countries have been scientifically collaborating on this important topic? Where are the scientific knowledge gaps, and indirectly where might research capacities need to be strengthened? In order to answer these queries, we analyzed the global scientific production (2020-2021) on COVID-19 associated inequalities by conducting bibliometric and network analyses using the Scopus database. Specifically, we analyzed the volume of scientific production per country (via author affiliations), its distribution by country income groups and world regions, as well as the inter-country collaborations within this production. Our results indicate that the COVID-19 inequalities research field has been highly collaborative; however, a number of significant inequitable research practices exist. When compared to the (pre-COVID-19) global health inequalities research field, similar inequalities were identified, however, several new dynamics and partnerships have also emerged that warrant further in-depth exploration. To ensure preparedness for future crises, and effective strategies to tackle growing social inequalities in health, investment in global health inequalities research capacities must be a priority for all.
    DOI:  https://doi.org/10.1371/journal.pone.0266132
  61. Front Res Metr Anal. 2022 ;7 817821
      Research is a critical component of the public health enterprise, and a key component of universities and schools of public health and medicine. To satisfy varying levels of stakeholders in the field of public health research, accurately measuring the return on investment (ROI) is important; unfortunately, there is no approach or set of defined metrics that are universally accepted for such assessment. We propose a research metrics framework to address this gap in higher education. After a selected review of existing frameworks, we identified seven elements of the generic research lifecycle (five internal to an institution and two external). A systems approach was then used to broadly define four parts of each element: inputs, processes, outputs, and outcomes (or impacts). Inputs include variables necessary to execute research activities such as human capital and finances. Processes are the pathways of measurement to track research performance through all phases of a study. Outputs entail immediate products from research; and outcomes/impacts demonstrate the contribution research makes within and beyond an institution. This framework enables the tracking and measurement of research investments to outcomes. We acknowledge some of the challenges in applying this framework including the lack of standardization in research metrics, disagreement on defining impact among stakeholders, and limitations in resources for implementing the framework and collecting relevant data. However, we suggest that this proposed framework is a systematic way to raise awareness about the role of research and standardize the measurement of ROI across health science schools and universities.
    Keywords:  health research; public health; research impact; research measurement; research metrics; research outcomes
    DOI:  https://doi.org/10.3389/frma.2022.817821