bims-evares Biomed News
on Evaluation of research
Issue of 2022–04–17
38 papers selected by
Thomas Krichel, Open Library Society



  1. Genomics Inform. 2022 Mar;20(1): e10
      Human exposure to pollutants has been on the rise. Thus, researchers have been focused on understanding the effect of these compounds on human health, especially on the genetic information by using various tests, among them the somatic mutation and recombination tests (SMARTs). It is a sensitive and accurate method applicable to genotoxicity analysis. Here, a comprehensive bibliometric analysis of SMART assays in genotoxicity studies was performed to assess publication trends of this field. Data were extracted from the Web of Science database and analyzed by the bibliometric tools HistCite, Biblioshiny (RStudio), VOSViewer, and CiteSpace. Results have shown an increase in the last 10 years in terms of publication. A total of 392 records were published in 96 sources mainly from Brazil, Spain, and Turkey. Research collaboration networks between countries and authors were performed. Based on document co-citation, five large research clusters were identified and analyzed. The youngest research frontier emphasized on nanoparticles. With this study, how research trends evolve over years was demonstrated. Thus, international collaboration could be enhanced, and a promising field could be developed.
    Keywords:  Drosophila; SMART; Web of Science; bibliometric; cancer; genotoxicity
    DOI:  https://doi.org/10.5808/gi.21083
  2. Clin Exp Med. 2022 Apr 13.
      Breast cancer is the most frequent cause of death from cancer in 12 regions of the world. Among the breast cancer subtypes, triple-negative breast cancer (TNBC) is the most aggressive, leading to an adverse prognosis. Thus, we aimed to identify the top 100 most cited articles regarding TNBC through bibliometric analyses, to explore their current impact and publication status. We searched TNBC-related articles from the Web of Science core database on September 19, 2021, and ranked them by citation in descending order. Information extracted from the top 100 most cited articles, included title, author, institution, country, year, publication, Journal Cited Rank, citation, Web of Science category, were extracted by two researchers independently. VOSviewer was used to analyze data, such as co-authoring institutions, and author cooperation. Descriptive statistical analysis of data was performed using Excel. Citations from the top 100 most cited articles ranged from 225 to 2753, and all were published after 2007. The top 100 most cited articles were published in 38 journals, with the Journal of Clinical Oncology published the most (n = 15), followed by Clinical Cancer Research (n = 11), Lancet Oncology(n = 6). Eric P. Winer from USA, who participated 12 articles, was the most frequently published author. The USA (n = 71) was the country with the most contributions to TNBC. The most prevalent topics included: clinical features, molecular subtypes, relevant influencing factors, exploration of treatment options and prognosis of TNBC. The leading institution was the Dana Farber Cancer Institute (n = 20) from the USA. This is the first bibliometric analysis on the TNBC 100 most cited article. We provided insights into the most cited articles on TNBC and listed a detailed description of their characteristics and trend, which provides ideas for further study.
    Keywords:  Bibliometric analysis; Citation; TNBC; Triple-negative breast cancer; VOSviewer; Web of Science
    DOI:  https://doi.org/10.1007/s10238-022-00800-9
  3. Skin Appendage Disord. 2022 Mar;8(2): 122-128
       Introduction: Bibliometric analysis provides an objective assessment of current research patterns and highlights the impact of selected publications in any given scientific discipline.
    Methods: We sought to provide information about dynamic research trends in nail psoriasis by analyzing the 50 most cited articles on this topic, which were identified utilizing the Scopus citation database.
    Results: The median number of citations was 79 (range, 60-337) per article. Publication dates ranged from 1969 to 2020, while the majority of articles (46%) were published between 2000 and 2009. The top 50 highly cited articles were published in 19 different journals, with a median impact factor of 5.248 (range, 1.022-16.102). The British Journal of Dermatology published the greatest number of highly cited articles (n = 9). Most publications were original articles, and most cited research topics included medical treatment and correlation of nail psoriasis with psoriatic arthritis. Most publications originated from the USA and UK, while Phoebe Rich and Dennis McGonagle were the two most contributing authors.
    Conclusion: This analysis provides information about emerging bibliometric trends and may guide future research in the field of nail psoriasis.
    Keywords:  Bibliometric analysis; Citation; Impact factor; Nail psoriasis; Scopus
    DOI:  https://doi.org/10.1159/000519191
  4. Front Med (Lausanne). 2022 ;9 869004
       Background: Over the past 40 years, endoscopic ultrasound (EUS) has become a safe and effective tool for both diagnostic and therapeutic applications. A growing number of articles have been published annually. We aimed to explore global scientific outputs and hotspots of EUS published by different countries, organizations, and authors.
    Methods: The global literature regarding EUS during the 1900-2020 period was identified from the Web of Science (WOS) Core database. "Bibliometrix" and software VOSviewer were applied to perform bibliometric analysis.
    Results: The annual growth rate of publications from 1980 to 2020 was around 16% and the number of EUS-related articles had experienced a sudden increase in the last decade. Bhutani MS was the most productive author over the past years, with 94 publications. Hawes RH had the highest number of citations, with 6,034 citations. The United States and institutions from United States dominated the EUS research. Among the journals, GASTROINTESTINAL ENDOSCOPY published the highest number of articles, followed by ENDOSCOPY. The majority of top 10 frequently cited references were cited more than 200 times. Carcinoma, diagnosis, fine-needle-aspiration, cytology, and pancreatitis were the important keywords in co-occurrence analysis of keywords. Recent studies focused more on tissue acquisition, size of the needle, lumen-apposing metal stent, and fine-needle- biopsy.
    Conclusion: Research on EUS has significantly increased in the last decade globally and it will continue to increase. Active collaboration among different authors and countries was observed in the EUS field. Tissue acquisition, size of the needle, apposing metal stent, and fine-needle-biopsy might be the latest research frontiers and should receive more attention.
    Keywords:  VOSviewer; bibliometric analysis; bibliometrix; endoscopic ultrasound; gastroentergology
    DOI:  https://doi.org/10.3389/fmed.2022.869004
  5. J Thorac Dis. 2022 Mar;14(3): 635-645
       Background: Heart failure is the end stage of various heart diseases. For patients with poor or ineffective response drug treatment, heart transplantation is a reasonable and effective option. With the accumulation of heart transplantation cases, there are more and more studies on the immune response after heart transplantation. The purpose of the present study was to provide a bibliometric analysis of the current status of studies related to immune responses after heart transplantation.
    Methods: We searched the Science Citation Index Expanded online database with the following search terms: "heart transplantation" and "immune response". CiteSpace software was used to analyze the search results, including the annual trend in the number of publications, the annual trend in the number of citations, the distribution of the countries and institutions to which the authors belonged, the distribution of authors, the distribution of the journals that published the literature, and the use of keywords.
    Results: A total of 1,393 related research papers were included. The top five countries with the greatest number of published papers were the USA, China, Germany, the UK, and Japan. The countries with active cooperation with other countries were the USA, the UK, Germany, China, and Canada. The top five research institutions with the greatest number of published papers were the University of Pittsburgh, Harvard University, Washington University, Stanford University, and Brigham & Women's Hospital. The research institutions with active cooperation with other institutions were the University of Pittsburgh, Stanford University, Harvard University, Brigham & Women's Hospital, and Harvard Medical School. The top five authors with the most published papers were David K. C. Cooper, Hidetaka Hara, Hayato Iwase, David Ayares, and Cassandra Long. Core journals were Transplantation, Journal of Immunology, and Proceedings of The National Academy of Sciences of The United States of America. Keyword analysis revealed that research hotspots changed over time.
    Conclusions: Research on immune response after heart transplantation is concentrated in a few countries, and more clinical research is needed in the future.
    Keywords:  Immune response; bibliometric analysis; heart transplantation
    DOI:  https://doi.org/10.21037/jtd-22-200
  6. J Cancer. 2022 ;13(6): 1785-1795
      Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma subtype. Treatment of DLBCL has improved greatly in recent decades, with thousands of papers published. We conducted a bibliometric analysis of the literature on DLBCL treatment, and discussed cooperation among authors, countries, and institutions, and identified research hotspots for DLBCL treatment. We searched the Web of Science Core Collection (WOSCC) using "Diffuse Large B Cell Lymphoma or DLBCL" and "Treatment or Therapy or Clinical Trial" as the subject terms, and analyzed the publication year, research direction, country/region, institution, author, source publication, distribution of funding institutions, and other conditions provided by the database. In addition, scientometrics software was used to analyze literature citations and cooperative publications. Bibliometric analyses were performed using https://bibliometric.com/app and VOSviewer. Network maps were generated to evaluate collaborations between different authors, countries, institutions, and keywords. A total of 7,255 studies on treatment of DLBCL were retrieved from the WOSCC on February 19, 2021. We found that the number of publications increased gradually from 1999 to 2021, and this trend was relatively stable in the past 3 years. The countries that produced the most publications were the United States, China, and Japan. Among institutions, University of Texas MD Anderson Cancer Center published the most manuscripts. Furthermore, the United States also had the most annual publications, citations, distribution of journal sources, and funding. Cooperative research between countries is also relatively important to treatment of DLBCL. Therapeutic regimens such as CHOP and R-CHOP, and immunotherapy (CAR-T, PD1/PDL1, and CAR-NK, etc.), have received increased attention. Bibliometric analysis of studies related to DLBCL treatment can help researchers and clinical workers quickly understand the hotspots and development trends in this field, and provide reference for the formulation of public health policies.
    Keywords:  VOSviewer; Visualized; bibliometric analysis; diffuse large B-cell Lymphoma (DLBCL); research progress; treatment
    DOI:  https://doi.org/10.7150/jca.68453
  7. Front Psychiatry. 2022 ;13 853953
       Objectives: First dedicated articles about placebo effects have been published in the 1940s, and more than 5,000 articles have been published in scientific organs since. However, the evolution of this research field has rarely been examined. By means of bibliometric analyses we aim to generate research metrics such as the number and types of publications as well as topics, authorship networks, impacts, and future directions.
    Methods: Bibliometric methods were applied to the Journal of Interdisciplinary Placebo Studies (JIPS) database. It comprises around 5,000 scientific articles dedicated to researching placebo effects and mechanisms and is expanded continually through individual curation, making it a prime candidate for investigation. Web scraping was used to obtain complete article information from PubMed and Web of Science. The same information was obtained for addiction research as reference field. Analyses include a general characterization of the database as well as focus points concerning publication types (data vs. non-data articles), high-impact publications and more.
    Results: Analyses show that the JIPS database is a comprehensive collection of placebo publications. The development of the field is comparable to that of the comparator field and scientific publication in general. The most frequently used keywords describe populations or study design topics; the most frequent symptoms were pain, depression and anxiety. Data and non-data (e.g., review) papers are related in proportion of about 6:4 in recent decades, indicating a stable degree of productivity. A network of 26 interconnected researchers was identified who published 25 or more articles. Placebo research contributes comparable numbers of publications to high-impact journals as the comparator field. Several additional analyses are performed, with a focus on visualization of various database parameters.
    Conclusions: Bibliometric analyses of the JIPS database can be used to answer questions to the field, for example, to get an impression of blind spots and future directions. However, keywords used in indexing and publications themselves are often general and suggest that placebo research may still be considered a subspecialty of superordinate fields, particularly since there are no journals dedicated to placebo research itself. We invite interested colleagues to use this database for further analyses.
    Keywords:  authorship; bibliometrics; journal impact factor; placebo effect; publications
    DOI:  https://doi.org/10.3389/fpsyt.2022.853953
  8. Turk J Gastroenterol. 2022 Mar;33(3): 221-232
       BACKGROUND: The number of times that an article is cited could reflect its impact. This study aims to recognize and analyze the characteristics of the most frequently cited articles in the field of colorectal diseases.
    METHODS: We identified the 100 most-cited articles using the terms "colorectal," "colon," "rectal," "IBD," "ulcerative colitis," "Crohn's disease," or "colonoscopy" in Web of Science. The articles were analyzed to evaluate the characteristics, including the number of citations, country of origin, the institution of origin based on the first author's affiliation, study type, and others.
    RESULTS: Of the top-cited publications, the number of citations ranged from 1575 to 9283, with a mean of 2504.11 citations. The journal with the greatest number of most-cited articles was the New England Journal of Medicine (n = 23), followed by Science (n = 14) and Nature (n = 12). These papers were published in 14 different countries, of which more than half were from the United States (n = 60). The most popular field was colorectal cancer (n = 45), followed by colon tumors (n = 21). Most of the papers were basic science studies (n = 43) and randomized controlled trials (n = 30). Regarding the level of evidence, there were 5 studies at level I, 29 at level II, and 5, 1, and 15 studies at levels III, IV, and V, respectively.
    CONCLUSION: Our study could provide a historical perspective on scientific progress in the field of colorectal diseases. These 100 mostcited articles are of great significance for helping researchers understand this field over time.
    DOI:  https://doi.org/10.5152/tjg.2021.20901
  9. J Physician Assist Educ. 2022 Apr 15.
       PURPOSE: Little is known about physician assistant (PA) educators' publishing practices and the collective impact of their published works. The goal of this study was to describe the scholarly output of the PA professoriate in a way that is useful to both promotion committees and individual educators who are planning careers.
    METHODS: A cross-sectional study was performed to demonstrate publishing patterns. The name of each PA-credentialed educator in academic health centers was searched in Scopus. Citations of peer-reviewed articles published through 2019 were retrieved and de-duplicated. The number of publications, h-indices, journal names, and keywords were collected between May 2019 and January 2020. Differences among academic ranks were explored, and keywords were analyzed. Frequently used journals were determined and their impact factors retrieved.
    RESULTS: A total of 364 faculty met inclusion criteria. Between 1972 and 2019, 895 peer-reviewed articles were published; 603 were published in the last 10 years. Approximately half the study cohort (n = 172) published at least one peer-reviewed article that met inclusion criteria (range 1-89; median = 2). Overall, productivity remained steady over the last 10 years (range 0-59; median = 2). Faculty at the professor and associate level had a median h-index of 2.00 and assistants had a median h-index of 1.00. PhD-prepared faculty published more articles and had higher h-indices than faculty with other types of degrees.
    CONCLUSIONS: The results provide benchmarking data that can be used for promotion and professional development. More faculty must publish and increase the citation rate of their publications if we are to improve the reputation of the PA educator literature.
    DOI:  https://doi.org/10.1097/JPA.0000000000000417
  10. Front Cardiovasc Med. 2022 ;9 804463
       Background: Metabolomics has immense research value in coronary artery disease and has drawn increasing attention over the past decades. Many articles have been published in this field, which may challenge researchers aiming to investigate all the available information. However, bibliometrics can provide deep insights into this research field.
    Objective: We aimed to qualitatively and quantitatively study metabolomics and coronary artery disease research, visually analyse the development status, trends, research hotspots, and frontiers of this field, and provide a reference for research on coronary artery disease.
    Methods: Articles were acquired from the Web of Science Core Collection. VOSviewer and CiteSpace software were used to analyse publication growth, country/region, institution, journal distribution, author, reference, and keywords, and detected the keywords with strong citation burstness to identify emerging topics.
    Results: A total of 1121 references were obtained, and the annual number of publications increased over the past 16 years. Metabolomics research has shown a gradual upward trend in coronary artery disease. The United States of America and China ranked at the top in terms of percentage of articles. The institution with the highest number of research publications in this field was Harvard University, followed by the University of California System and Brigham Women's Hospital. The most frequently cited authors included Hazen SL, Tang WH, and Wang ZN. Ala-Korpela M was the most productive author, followed by Clish CB and Adamski J. The journal with the most publications in this field was Scientific Reports, followed by PLoS One and the Journal of Proteome Research. The keywords used at a high frequency were "risk," "biomarkers," "insulin resistance," and "atherosclerosis." Burst detection analysis of top keywords showed that "microbiota," "tryptophan," and "diabetes" are the current research frontiers in this field.
    Conclusion: This study provides useful information for acquiring knowledge on metabolomics and coronary artery diseases. Metabolomics research has shown a gradual upward trend in coronary artery disease studies over the past 16 years. Research on tryptophan metabolism regulated by intestinal flora will become an emerging academic trend in this field, which can offer guidance for more extensive and in-depth studies in the future.
    Keywords:  CiteSpace; VOSviewer; coronary artery disease; metabolomics; visual analytics
    DOI:  https://doi.org/10.3389/fcvm.2022.804463
  11. Int J Environ Res Public Health. 2022 Apr 05. pii: 4356. [Epub ahead of print]19(7):
      In the last few years, there has been an emphasis on the importance of health literacy (HL) and health education (HE) as basic tools to empower individuals and the community. The increasing interest in HL and HE has been observed through the evolution of publications and the nature of the main trends in the last few years. Knowing how HL and HE have evolved in scientific publications can help us to identify trends and set work priorities in this scope. Based on this, a bibliometric analysis (from 2000 to 2021) was conducted in two phases: first, an analysis was performed on the publications included in the Web of Science (WOS); second, a more specific analysis was conducted on the Core Collection from WOS. The data were analyzed with two software programs, the and Bibliometrix package for RStudio, and VOSviewer to analyze number of publications, citations, authors, collaborations, keywords trends, keywords evolutions and clusters of related terms. A total of 1799 articles were found in the first phase, and 727 in the second. The results from both analyses showed that the publications increased unequally until 2020, and considerably decreased in 2021; however, in spite of this, the number of citations remained constant. Likewise, five word clusters related with HL and HE were identified. D. Nutbeam stood out as the most prolific author on the subject, the USA as the country with the most publications, and the International Journal of Environmental Research and Public Health as having the most articles on the subject. This analysis may be a useful and helpful tool for future studies on the subject.
    Keywords:  RStudio; VOSviewer; bibliometric analysis; health education; health literacy; machine learning
    DOI:  https://doi.org/10.3390/ijerph19074356
  12. PLoS One. 2022 ;17(4): e0265831
      Cumulative advantage-commonly known as the Matthew Effect-influences academic output and careers. Given the challenge and uncertainty of gauging the quality of academic research, gatekeepers often possess incentives to prefer the work of established academics. Such preferences breach scientific norms of universalism and can stifle innovation. This article analyzes repeat authors within academic journals as a possible exemplar of the Matthew Effect. Using publication data for 347 economics journals from 1980-2017, as well as from three major generalist science journals, we analyze how articles written by repeat authors fare vis-à-vis less-experienced authors. Results show that articles written by repeat authors steadily decline in citation impact with each additional repeat authorship. Despite these declines, repeat authors also tend to garner more citations than debut authors. These contrasting results suggest both benefits and drawbacks associated with repeat authorships. Journals appear to respond to feedback from previous publications, as more-cited authors in a journal are more likely to be selected for repeat authorships. Institutional characteristics of journals also affect the likelihood of repeat authorship, as well as citation outcomes. Repeat authorships-particularly in leading academic journals-reflect innovative incentives and professional reward structures, while also influencing the intellectual content of science.
    DOI:  https://doi.org/10.1371/journal.pone.0265831
  13. J Nurs Manag. 2022 Apr 16.
       AIM: This study conducted a bibliometric analysis of nursing publications on the COVID-19 between January 1, 2020, and October 24, 2021.
    BACKGROUND: COVID-19 has been a hot research topic that has attracted many researchers from various disciplines. One of the ways to combat the COVID-19 pandemic is to produce knowledge and present it with a holistic approach. Therefore, it is crucial to make bibliometric and content analyses of scientific publications. Scientific data should be evaluated to keep up with the developments in the nursing profession and practices during the COVID-19 pandemic.
    METHODS: Data were collected from the Web of Science database. The sample consisted of 1280 publications that met the inclusion criteria. The data were analyzed using descriptive content and bibliometric analysis. The VOSviewer, a mapping and visualization software program, was used for bibliometric analysis.
    RESULTS: The USA is one of the countries with the highest number of publications, citations, and international cooperation during the pandemic. Of all these publications, 1183 (92.42%) are original articles. The Journal of Nursing Management has the highest number of publications and citations. The publications focus primarily on the topics of COVID-19, pandemic, nursing, coronavirus, and nurses. The current topics that the publications address are online education, online learning, practice, nursing student, perceived stress, stress, fear, quality of life, and experience to determine the impacts of the pandemic on mental health nursing education.
    CONCLUSIONS: The COVID-19 pandemic has an impact on nursing, and the number of publications is increasing worldwide. In the early days of the pandemic, researchers focused on the topics of coronavirus infections, infection control, global health, health policy, and nursing policy. Afterward, they addressed current topics, such as education and the psychological effects of the pandemic.
    IMPLICATIONS FOR NURSING MANAGEMENT: Our results will help nurse managers identify issues related to COVID-19 that have not been researched yet and have not been adequately explained in their own institutions. They will also help them choose appropriate journals to get their studies published, appropriate countries to cooperate with, and access information about the studies on the subject matter. Our results will also help them make evidence-based decisions about mental health and nursing education.
    Keywords:  COVID-19; VOSviewer; Web of Science; bibliometric analysis; content analysis; nursing
    DOI:  https://doi.org/10.1111/jonm.13636
  14. Int J Environ Res Public Health. 2022 Mar 31. pii: 4142. [Epub ahead of print]19(7):
      Environmental audit is inevitably linked to climate change, one immediate target of the auditors is likely to be climate control, and the warming of the Earth and the consequent climatic changes affect us all. What is the link between environmental audit and climate change? What ties together some of these themes between environmental audit and climate change? The interaction between climate change and environmental audit has been one of the most challenging. In this paper, a scientometric analysis of 84 academic publications between 2013 and 2021 related to climate change and environmental audit is presented to characterize the knowledge domain by using the CiteSpace visualization software. First, we present the number of publications, the number of citations, research categories, and journals published through Web of Science database. Secondly, we analyze countries, authors, and journals with outstanding contributions through network analysis. Finally, we use keyword analysis and apply three types of knowledge mapping to our research, cluster view, timeline view, and time zone view, revealing the focus and future directions. We identify the most important topic in the field of climate change and environment audit as represented on the basis of existing literature data which include the Carbon Emissions, Social Capital, Energy Audit, Corporate Governance, Diffusion of Innovation Environmental Management System, and Audit Committee. The results show that climate change and environmental audit publications grew slowly, but the research are widely cited by scholars. Published journals are relatively scattered, but the cited journals are the world's top journals, and most research countries are developed countries. The most productive authors and institutions in this subject area are in UK, Australia, USA, Spain, and Netherlands. There are no leading figures, but the content of their research can be divided into six clusters. Future research content involving city, policy, dynamics, information, biodiversity, conservation and clustering social capital, diffusion of innovation environmental management, and audit committee are the directions for future research. It is worth noting that cities, policies, and adaptability are closely linked to public health.
    Keywords:  climate change; environmental audit; knowledge map; public health
    DOI:  https://doi.org/10.3390/ijerph19074142
  15. Front Res Metr Anal. 2022 ;7 862537
       Background: Impact factor (IF) is a quantitative tool designed to evaluate scientific journals' excellence. There was an unprecedented upsurge in biomedical journals' IF in 2020, perhaps contributed by the increased number of publications since the COVID-19 outbreak. We conducted a cross-sectional study (2018-2020) to analyze recent trends in standard bibliometrics (IF, Eigenfactor, SNIP) of pediatric journals. We also estimated reference and publication counts of biomedical journals since publication volume determines the number of citations offered and IF.
    Methods: Various bibliometrics of pediatric journals and reference/publication volumes of biomedical journals were compared between 2020 vs. 2019 and 2019 vs. 2018. We also compared open access (OA) and subscription journals' trends. Finally, we estimated IF changes in the journals of a different specialty, pulmonology.
    Results: The study included 164 pediatric and 4,918 biomedical journals (OA = 1,473, subscription = 3,445). Pediatric journals' IFs had increased significantly in 2020 [median (IQR) = 2.35 (1.34)] vs. 2019 [1.82 (1.22)] (Wilcoxon: p-value < 0.001). IFs were unchanged between 2018 and 2019. Eigenfactor remained stable between 2018 and 2020, while SNIP increased progressively. Reference/publication volumes of biomedical journals escalated between 2018 and 2020, and OA journals experienced faster growth than subscription journals. IFs of pulmonary journals also increased considerably in 2020 vs. 2019.
    Conclusions: We report an upsurge in pediatric journals' IF, perhaps contributed by a sudden increase in publication numbers in 2020. Therefore, considering this limitation, IF should be cautiously used as the benchmark of excellence. Unlike IF, Eigenfactor remained stable between 2018 and 2020. Similar changes in IF were also observed among the journals of another specialty, pulmonology.
    Keywords:  COVID-19; Eigenfactor; SNIP; bibliometrics; impact factor; open access journals; publication bias
    DOI:  https://doi.org/10.3389/frma.2022.862537
  16. PLoS One. 2022 ;17(4): e0266404
      Interdisciplinary scientific collaboration promotes the innovative development of scientific research. Photocatalytic hydrogen evolution (PHE) is a typical interdisciplinary subject. This study aims to explore the characteristics of discipline interaction and the temporal evolution in the field. Bibliometric analysis could be used to understand the stage of research in a particular subject. In this work, the publications on the topic in Web of Science (WoS) platform from 1999 to 2020 were selected. On the basis of social network theory, the characteristics of interdisciplinary were revealed from three perspectives. First, the disciplinary interaction network is constructed through disciplinary co-occurrence to detect the characteristics of interaction structure among different disciplines. Then the node centrality index is employed to explore the influence of disciplines in the interactive network by using network centrality analysis. Moreover, the dynamic of discipline interaction evolution is studied using blockmodeling analysis. In the field of PHE, the number of disciplines and the intensity of interaction among different subjects gradually increased in the past 20 years. Chemistry and Material Sciences are the core discipline, and they play an important role in the network. The whole network is divided into different discipline groups. The scale of the discipline group is becoming large, and the disciplinary interaction is becoming more complex. The obtained results are helpful for guiding scholars to carry out interdisciplinary interaction. The methods of detecting interdisciplinary interactive relationship could provide paths for interdisciplinary research in other fields.
    DOI:  https://doi.org/10.1371/journal.pone.0266404
  17. Int J Environ Res Public Health. 2022 Mar 31. pii: 4165. [Epub ahead of print]19(7):
      The increasing application of nutrition in cancer management has attracted a great deal of research interest in recent decades. Nutritional therapies, interventions, and assessments were known to have positive effects on reducing side effects from cancer therapy. In order to identify the global research output for nutrition in cancer research, a bibliometric analysis during the past 10 years was conducted to evaluate the current status of trends, gaps, and research directions as no bibliometric studies have been conducted regarding nutrition and cancer. After the data collection, a total of 1521 articles were chosen for this bibliometric study. The visualization analysis was performed with VOSviewer. The number of publications has grown continuously since a substantial spark was identified in 2019. The majority of the authors' affiliations were in European countries. Four cancer types were recognized among the top 10 author keywords; they were breast cancer, head and neck cancer, colorectal cancer, and gastric cancer. The Nutrients journal was the most popular among the authors as the journal published 195 articles related to the topic. In conclusion, providing evidence-based nutritional solutions for various types of cancer is essential to nutrition and cancer research. Since it is presumed to have a growing number of cancer patients worldwide with the aging population, it is vital to continuously generate research finding effective nutrition therapies for cancer patients.
    Keywords:  bibliometric; cancer care; cancer management; nutrition; nutrition therapy
    DOI:  https://doi.org/10.3390/ijerph19074165
  18. PLoS One. 2022 ;17(4): e0266565
      This paper primarily aims to provide a citation-based method for exploring the scholarly network of artificial intelligence (AI)-related research in the information science (IS) domain, especially from Global North (GN) and Global South (GS) perspectives. Three research objectives were addressed, namely (1) the publication patterns in the field, (2) the most influential articles and researched keywords in the field, and (3) the visualization of the scholarly network between GN and GS researchers between the years 2010 and 2020. On the basis of the PRISMA statement, longitudinal research data were retrieved from the Web of Science and analyzed. Thirty-two AI-related keywords were used to retrieve relevant quality articles. Finally, 149 articles accompanying the follow-up 8838 citing articles were identified as eligible sources. A co-citation network analysis was adopted to scientifically visualize the intellectual structure of AI research in GN and GS networks. The results revealed that the United States, Australia, and the United Kingdom are the most productive GN countries; by contrast, China and India are the most productive GS countries. Next, the 10 most frequently co-cited AI research articles in the IS domain were identified. Third, the scholarly networks of AI research in the GN and GS areas were visualized. Between 2010 and 2015, GN researchers in the IS domain focused on applied research involving intelligent systems (e.g., decision support systems); between 2016 and 2020, GS researchers focused on big data applications (e.g., geospatial big data research). Both GN and GS researchers focused on technology adoption research (e.g., AI-related products and services) throughout the investigated period. Overall, this paper reveals the intellectual structure of the scholarly network on AI research and several applications in the IS literature. The findings provide research-based evidence for expanding global AI research.
    DOI:  https://doi.org/10.1371/journal.pone.0266565
  19. Front Oncol. 2022 ;12 832385
      Machine learning and semantic analysis are computer-based methods to evaluate complex relationships and predict future perspectives. We used these technologies to define recent, current and future topics in pancreatic cancer research. Publications indexed under the Medical Subject Headings (MeSH) term 'Pancreatic Neoplasms' from January 1996 to October 2021 were downloaded from PubMed. Using the statistical computing language R and the interpreted, high-level, general-purpose programming language Python, we extracted publication dates, geographic information, and abstracts from each publication's metadata for bibliometric analyses. The generative statistical algorithm "latent Dirichlet allocation" (LDA) was applied to identify specific research topics and trends. The unsupervised "Louvain algorithm" was used to establish a network to identify relationships between single topics. A total of 60,296 publications were identified and analyzed. The publications were derived from 133 countries, mostly from the Northern Hemisphere. For the term "pancreatic cancer research", 12,058 MeSH terms appeared 1,395,060 times. Among them, we identified the four main topics "Clinical Manifestation and Diagnosis", "Review and Management", "Treatment Studies", and "Basic Research". The number of publications has increased rapidly during the past 25 years. Based on the number of publications, the algorithm predicted that "Immunotherapy", Prognostic research", "Protein expression", "Case reports", "Gemcitabine and mechanism", "Clinical study of gemcitabine", "Operation and postoperation", "Chemotherapy and resection", and "Review and management" as current research topics. To our knowledge, this is the first study on this subject of pancreatic cancer research, which has become possible due to the improvement of algorithms and hardware.
    Keywords:  Python (programming language); bibliometric (R-package); latent Dirichlet allocation (LDA) algorithm; machine learning; natural language processing (NLP); pancreatic ductal adenocarcinoma
    DOI:  https://doi.org/10.3389/fonc.2022.832385
  20. Environ Sci Pollut Res Int. 2022 Apr 15.
      In this paper, Web of Science (a database) is used to retrieve related literature in the field of heavy metal pollution in desert. CiteSpace is used to make a quantitative and qualitative evaluation on the literature in the field on the basis of a brief analysis on the research status, research focus, and evolution process in the field. Through CiteSpace visual analysis, a comparative analysis is given on related literature in terms of annual number of published papers, author groups, and their countries and regions, journals, publishing institutions, highly cited papers, research focuses, and burst terms, so as to explore the research status and future development trend of the field on a global scale. The results are shown as follows: (1) The literature in the field was originally published in 2000; the number of published papers increased steadily. The literature was mostly published on high-quality journals, the USA topped in terms of the number of published papers, and the research results achieved by developed countries had a greater influence. Chinese Acad Sci topped with the highest centrality and most published papers, which have made outstanding contributions to the field and occupy a leading position in the field. However, the fact is that there lacks communication and cooperation among research institutions. The most influential journal is Science of the Total Environment. (2) The hot research words in the field are as follows: heavy metal, soil, pollution, lead, desert, cadmium, and microelement. (3) In the field, burst terms have transformed from atmospheric deposition, biomonitoring, and phytoremediation to trace element, stream sediment, street dust, and water quality, and finally transformed to river and sediment. New words keep emerging in the research, and more and more attention is paid to the issue of heavy metal pollution in river sediment, which will be a future research hotspot in the field.
    Keywords:  CiteSpace; Desert; Heavy metal; Visual analysis
    DOI:  https://doi.org/10.1007/s11356-022-20216-y
  21. RSC Adv. 2022 Feb 03. 12(8): 4973-4987
      Microplastics (MPs) and per- and polyfluoroalkyl substances (PFAS) are ubiquitous in the environment due to consumer and industrial use. These compounds are very persistent in the environment and human body, which has made them hot environmental topics in recent years; but how this did come about? What factors have been driving the trends of their publication records, the public concern over environmental and public health issues caused by these pollutants, and the collaboration between scientists, regulators, and policymakers to solve these problems? In this paper, to understand these factors and contrast them between the two hot topics ("PFAS" and "MPs"), the changes in the bibliometric and scientometric trends of their publication records (extracted from the Web of Science from 1990 to 2020) have been visualized over time based on different classification perspectives, such as year, country, source, and organization. According to the analyses performed on these records, utilizing publication ratios and principal component and cluster analyses, in recent years (beginning in 2018) research topics related to MPs have surpassed PFAS topics. In addition, the economic, social, and geographical conditions of the top 20 countries with the highest number of publications in MPs and PFAS were explored to identify which countries are most concerned about each of these topics and why. For instance, PFAS research topics were more prevalant in countries with larger water areas compared to land area; while MPs topic were more prevelant in countries that produced more plastic wastes, and had higher landfilling and recycling rates and greater proportion of treated wastewater.
    DOI:  https://doi.org/10.1039/d1ra09344d
  22. GM Crops Food. 2022 Dec 31. 13(1): 65-85
      In this study, we present the bibliometric trends emerging from research outputs on consumer perception and preference for genetically modified (GM) foods and policy prescriptions for enabling the consumption using VOSviewer visualization software. Consumers' positive response is largely influenced by the decision of the governments to ban or approve the GM crops cultivation. Similarly, the public support increases when the potential benefits of the technology are well articulated, consumption increases with a price discount, people's trust on the government and belief in science increases with a positive influence by the media. Europe and the USA are the first region and country, respectively, in terms of the number of active institutions per research output, per-capita GDP publication and citations. We suggest research-, agri-food industries-, and society-oriented policies to be implemented by the stakeholders to ensure the safety of GM foods, encourage consumer-based studies, and increase public awareness toward these food products.
    Keywords:  Bibliometric analysis; GM food; GMOs; consumer perception; consumer preferences; future research thrust; industry implications; policy imperatives
    DOI:  https://doi.org/10.1080/21645698.2022.2038525
  23. Cancers (Basel). 2022 Mar 27. pii: 1697. [Epub ahead of print]14(7):
      Squamous-cell carcinoma of the anus (ASCC) is a rare disease. Barriers have been encountered to conduct clinical and translational research in this setting. Despite this, ASCC has been a prime example of collaboration amongst researchers. We performed a bibliometric analysis of ASCC-related literature of the last 20 years, exploring common patterns in research, tracking collaboration and identifying gaps. The electronic Scopus database was searched using the keywords "anal cancer", to include manuscripts published in English, between 2000 and 2020. Data analysis was performed using R-Studio 0.98.1091 software. A machine-learning bibliometric method was applied. The bibliometrix R package was used. A total of 2322 scientific documents was found. The average annual growth rate in publication was around 40% during 2000-2020. The five most productive countries were United States of America (USA), United Kingdom (UK), France, Italy and Australia. The USA and UK had the greatest link strength of international collaboration (22.6% and 19.0%). Two main clusters of keywords for published research were identified: (a) prevention and screening and (b) overall management. Emerging topics included imaging, biomarkers and patient-reported outcomes. Further efforts are required to increase collaboration and funding to sustain future research in the setting of ASCC.
    Keywords:  HIV; HPV; anal cancer; bibliometrics; machine learning; oncology; radiotherapy; squamous-cell carcinoma
    DOI:  https://doi.org/10.3390/cancers14071697
  24. J Surg Res. 2022 Apr 09. pii: S0022-4804(22)00140-8. [Epub ahead of print]276 298-304
       INTRODUCTION: It is unknown whether the ranking of plastic surgery residency programs influences resident research output. This study aims to determine whether program reputation and other factors are associated with integrated plastic surgery resident academic productivity.
    MATERIALS AND METHODS: Programs were divided into four tiers based on Doximity reputation rankings. Residents from 2019 to 2020 were found through program websites and social media accounts. Works published during residency were identified through PubMed and Scopus from July 1 of each resident's intern year to August 10, 2020. Variables included resident demographics and medical school, residency reputation ranking, geographic region, and medical school affiliation. 'High research output' was defined as having ≥75th percentile of publications adjusted by training year.
    RESULTS: In total, 921 residents in 80 programs were identified. The median (IQR) number of total publications and original articles was 3 (1-6) and 2 (0-4), respectively. On multivariable analysis, residents in top-20 ranked programs (OR = 2.31, 95% CI [1.55; 3.43], P < 0.001) or from programs associated with top-20 medical schools (OR = 1.61, 95% CI [1.08; 2.41], P = 0.020) were more likely to have higher research output. On the other hand, coming from a top-50 in research medical school (OR = 1.80, 95% CI [1.31; 2.47], P < 0.001) or being in a program affiliated with a top-20 medical school (OR = 2.52, 95% CI [1.69; 3.78], P < 0.001) were associated with higher original article output. Gender and geographic location were not associated with higher research output.
    CONCLUSIONS: Program reputation and affiliated medical school research rankings are associated with research productivity during integrated plastic surgery residency. Applicants with a particular interest in research careers may consider this as they apply to residency.
    Keywords:  Plastic surgery; Reputation; Research; Residency
    DOI:  https://doi.org/10.1016/j.jss.2022.03.003
  25. J Hand Surg Glob Online. 2020 Jul;2(4): 182-185
       Purpose: To determine whether demographic differences exist among editors, reviewers, and authors in The Journal of Hand Surgery (JHS). We aimed to test the null hypothesis that there would be no difference among these 3 groups with respect to gender, geographic location, academic productivity, and financial relationships with industry.
    Methods: Editors, reviewers, and physician authors were identified for 2018 JHS. Gender and geographic location were recorded for each person. We used the Scopus database to determine the Hirsch index (h-index) as well as the number of publications and citations for members of each group. Industry payment information was obtained using the Open Payments Web site.
    Results: The editor group contained 20% women compared with the author group (17% women). Authors (59%) were less likely to be from the United States compared with editors (91%) and reviewers (88%). Editors were found to have a higher h-index (16) compared with reviewers (14) and authors (12). Authors demonstrated significantly higher mean total payments from industry ($41,738) compared with editors ($13,712) and reviewers ($20,457).
    Conclusions: In 2018, there appeared to be an even distribution with respect to gender among editors, authors and reviewers in the JHS. International editors and reviewers are relatively under-represented compared to authors. Whereas editors and reviewers demonstrated higher h-indices compared with authors, JHS authors had significantly higher mean total payments in the Open Payments database.
    Clinical relevance: Defining demographics, academic productivity, and conflicts of interest for journal editors, reviewers, and authors may aid in identifying potential sources of both author and peer review bias.
    Keywords:  Authorship; Diversity; Gender; Hand surgery; Peer review
    DOI:  https://doi.org/10.1016/j.jhsg.2020.05.002
  26. World Neurosurg. 2022 Apr 11. pii: S1878-8750(22)00459-4. [Epub ahead of print]
       OBJECTIVES: With the recent paradigm shift in neurosurgical publications, open access (OA) publishing is burgeoning along with traditional publishing methods. We aimed to explore costs of publication across 53 journals.
    METHODS: We identified 53 journals publishing neurosurgical work. Journal type, submission and open access charges, colour print fees, impact indicators, publisher, and subscription prices were obtained from journal and publisher websites. Costs were unified in American Dollars. Mean prices per journal were used to equilibrate membership and subscription discounts. Correlations were performed using Spearman Rho (ρ), p<0.05.
    RESULTS: Of the 53 journals, 12 are OA-only, 40 are hybrid, and 1 is traditional. 22 and 43 journals provide their submission costs by end of phase 1 and 2, respectively (prices always for phase 2; 26 free of charge, 4 under $500, and 1 under $1000). Median OA charge is $3286 (49 journals; range $0-$7827). 36 of the 53 journals did not list print fees for colour figures (29 in phase 2). Median fee estimate per figure is $422 (range $25-$1060). Median personal subscription for 1 year is $344 (range $60-$1158; 48 journals). Median institutional subscription for 1 year is $2082 (Range $38-$5510; 34 journals). There is mild positive correlation between journal impact factor and OA fees (ρ=0.287, p=0.046).
    CONCLUSIONS: The lack of easily accessible information about Neurosurgical publications, such as submission costs, or OA charges create unnecessary hurdle and should be remedied. Publishing in Neurosurgery should be a pleasant learning experience for the cost anxiety should not be a limiting factor.
    Keywords:  cost; journal; neurosurgery; publication
    DOI:  https://doi.org/10.1016/j.wneu.2022.04.021
  27. Scand J Urol. 2022 Apr 11. 1-7
       OBJECTIVE: To investigate how urological studies using composite endpoints as the primary outcome were cited.
    MATERIALS AND METHODS: In this quality analysis of citations, three randomized clinical trials each investigating oncological and non-oncological urology were selected for citation analysis based on pre-defined criteria. In total, 531 papers citing the selected studies were reviewed; citations were evaluated based on whether they correctly referred to the composite endpoint and if singleton endpoints were defined and/or discussed.
    RESULTS: Among the citations, 223/531 (42%) referred to the composite endpoint, of which 217/223 (97.3%) correctly cited the composite endpoint. However, only 91/217 (41.9%) defined and/or discussed the singleton endpoints of the composite endpoint. The lack of a validated instrument for citation analysis was a limitation of this study. Meanwhile, the main strength is the large number of individually analyzed citations.
    CONCLUSIONS: The composite endpoints of urological randomized clinical trials are generally cited without referring to the composite endpoint; when cited, the composite endpoints are described correctly. However, in most cases, without defining or discussing the singleton endpoints.
    Keywords:  Randomized controlled trials; citations; composite endpoints; endpoints; urology
    DOI:  https://doi.org/10.1080/21681805.2022.2058607
  28. J Surg Res. 2022 Apr 07. pii: S0022-4804(22)00077-4. [Epub ahead of print]276 272-282
       INTRODUCTION: There is a paucity of literature evaluating research-funding differences between male and female surgeons. Our study aims to evaluate possible disparities in the National Institutes of Health (NIH) grant awards by surgeon gender, type of medical degree (MD/DO), and advanced degrees among six surgery specialties: general surgeons, neurosurgeons, urologists, obstetricians/gynecologists, plastic, and orthopedic surgeons, from 2015 to 2020.
    METHODS: A retrospective cohort study was performed investigating the number of NIH grants received by male and female surgeon-scientists overall and within each listed specialty, 2015-2020. As a surrogate for grants submitted, the proportion of active surgeon-scientists per specialty was used. A priori level of significance was defined as P < 0.05.
    RESULTS: After adjusting for confounders, male surgeons had a higher mean number of NIH grants and higher grant funding than female surgeons (P < 0.001 for both). Type of medical degree (MD/DO) was not significantly associated with NIH funding. An advanced degree was associated with NIH funding among neurosurgeons only (P < 0.05). Differences in the proportion of active surgeon-scientists and proportion of NIH grants received by male and female surgeon-scientists were found only in the fields of orthopedic surgery (5.8% female surgeons and received 20.7% of grants, P = 0.003) and plastic surgery (17.2% female surgeons and received 33.3% of grants, P = 0.01).
    CONCLUSIONS: Male surgeons received most of the total surgical NIH grants. However, funding for female surgeons in orthopedic and plastic surgery outpaces that of their male counterparts when compared to gender proportions in their respective field. Future studies should further investigate the effects of additional applicant demographics on securing NIH grant funding.
    Keywords:  Gender equity; Grant awards; Medical and advanced degrees; National Institutes of Health; Surgical specialties
    DOI:  https://doi.org/10.1016/j.jss.2022.02.009
  29. Gen Psychiatr. 2022 ;35(2): e100590
       Background: The ongoing pandemic has led to a global surge in coronavirus disease 2019 (COVID-19)-related mental health research. However, most related publications come from Western countries or China, and their findings cannot always be extrapolated to Arab countries.
    Aims: This study provides a quantitative and qualitative analysis of mental health research pertaining to Arab countries' response to the COVID-19 pandemic.
    Methods: A scoping review of the World Health Organization (WHO) COVID-19 database for publications on mental health was conducted by authors affiliated with Arab institutions, including articles from inception to 24 October 2020. The included publications were evaluated for their national distribution, international collaboration, publication type, and main research themes. Methodological quality analysis of the included research studies was performed using the original and modified versions of the Newcastle-Ottawa Scale.
    Results: In total, 102 articles were included in this study, averaging 4.6 articles per Arab country. Most of the articles emerged from the Kingdom of Saudi Arabia, Jordan, and Egypt. A majority of publications demonstrated international collaboration. Most of the publications were original research studies and cross-sectional in design. The predominant research theme was examining the pandemic's mental health effects on the general population and healthcare workers. Only 28.0% of the studies were of high methodological quality, whereas 41.5% were moderate and 30.5% were low in quality.
    Conclusions: Mental health research in response to the COVID-19 pandemic in the Arab region has quantitative and qualitative shortfalls. Arab institutions need to respond to the pandemic promptly in order to address the delineated research gap and to generate higher-quality research output.
    Keywords:  COVID-19; Mental Health; Psychiatry
    DOI:  https://doi.org/10.1136/gpsych-2021-100590
  30. J Clin Epidemiol. 2022 Apr 06. pii: S0895-4356(22)00084-1. [Epub ahead of print]
       OBJECTIVE: To evaluate for COVID-19 treatments without benefits in subsequent large RCTs how many of their most-cited clinical studies had declared favorable results.
    STUDY DESIGN: Scopus searches (December 23, 2021) identified articles on lopinavir-ritonavir, hydroxycholoroquine, azithromycin, remdesivir, convalescent plasma, colchicine or interferon (index interventions) that represented clinical trials and had >150 citations. Their conclusions were correlated with study design features. The ten most recent citations for the most-cited article on each index intervention were examined on whether they were critical to the highly-cited study. Altmetric scores were also obtained.
    RESULTS: 40 eligible articles of clinical studies had received >150 citations. 20/40 (50%) had favorable conclusions, 4 were equivocal. Highly-cited articles with favorable conclusions were rarely RCTs (3/20) while those without favorable conclusions were mostly RCTs (15/20, p=0.0003). Only 1 RCT with favorable conclusions had >160 patients. Citation counts correlated strongly with Altmetric scores, especially news items. Only 9 (15%) of 60 recent citations to the most highly-cited studies with favorable or equivocal conclusions were critical.
    CONCLUSION: Many clinical studies with favorable conclusions for largely ineffective COVID-19 treatments are uncritically heavily cited and disseminated. Early observational studies and small randomized trials may cause spurious claims of effectiveness that get perpetuated.
    Keywords:  COVID-19; bias; non-randomized studies; randomized controlled trials
    DOI:  https://doi.org/10.1016/j.jclinepi.2022.04.001
  31. J Postgrad Med. 2022 Apr 13.
       Introduction: Quality assessment of randomized controlled trials (RCTs) is important to prevent clinical application of erroneous results.
    Materials and Methods: This was an assessment of published RCTs in surgical subspecialties during 2011-2018 based on MEDLINE and EMBASE search. The primary objective of the present study was to quantitatively and qualitatively analyze the RCTs published from India based on year of publication, geographical distribution, and subspecialty using the modified Jadad score (high quality if score is ≥3; or ≥2 if blinded design was not feasible). Its secondary objective was to identify factors affecting the quality of RCTs.
    Results: Among 1304 trials identified, 162 were analyzed. Of these 96 (59%) had a score of ≥3; and 104 (64.2%) were of high quality (score ≥2). Year-wise there was no significant quantitative (P = 0.329) or qualitative (P = 0.255) variation. Geographic regions had similar quantity (P = 0.206) and quality (P = 0.068). The RCTs among subspecialties too were comparable in quantity and quality. Higher impact factor of journal (P = 0.013) and assessment by Institute Review Board (IRB) (P = 0.004) were significantly associated with a better study quality. Type of institution, number of authors, centricity, assistance by a statistician, and source of funding did not affect the quality of RCTs.
    Conclusions: The quantity and quality of surgical RCTs were stable and comparable over the years and across geographical regions and subspecialties. Higher impact factor of journal and review by IRB were significantly associated with a better study quality.
    Keywords:  Blinding; drop-out; quality assessment; randomization; reliability
    DOI:  https://doi.org/10.4103/jpgm.JPGM_104_21
  32. PLoS One. 2022 ;17(4): e0266855
      Consumer trust and organic food product credibility play a crucial role in understanding consumer behavior. The aim of this review is to identify extrinsic factors which influence consumers' perceived trust in organic food. The research was conducted based on the PRISMA guidelines. During our search, 429 articles were found, from which 55 studies were selected for further analysis. To assess the connection between the selected articles, a bibliometric analysis was done with VOSViewer and CitNetExplorer software. The following factors were identified as influencing the credibility of organic food: labeling, certification, place of purchase, country of origin, brand, price, communication, product category, packaging. From these, labeling, certification, and country of origin are well-researched factors in relation to credibility. The significance of the other discovered factors is supported; nonetheless, further research is needed to evaluate their effect on consumer trust.
    DOI:  https://doi.org/10.1371/journal.pone.0266855
  33. BMC Med Res Methodol. 2022 Apr 10. 22(1): 105
       INTRODUCTION: Over the last years, the number of systematic reviews published is steadily increasing due to the global interest in this type of evidence synthesis. However, little is known about the characteristics of this research published in Portuguese medical journals. This study aims to evaluate the publication trends and overall quality of these systematic reviews.
    MATERIAL AND METHODS: This was a methodological study. We aimed the most visible Portuguese medical journals indexed in MEDLINE. Systematic reviews were identified through an electronic search (through PUBMED). We included systematic reviews published up to August 2020. Systematic reviews selection and data extraction were done independently by three authors. The overall quality critical appraisal using the A MeaSurement Tool to Assess systematic Reviews (AMSTAR-2) was independently assessed by three authors. Disagreements were solved by consensus.
    RESULTS: Sixty-six systematic reviews published in 5 Portuguese medical journals were included. Most (n = 53; 80.3%) were systematic reviews without meta-analysis. Up to 2010 there was a steady increase in the number of systematic reviews published, followed by a period of great variability of publication, ranging from 1 to 10 in a given year. According to the systematic reviews' typology, most have been predominantly conducted to assess the effectiveness/efficacy of health interventions (n = 27; 40.9%). General and Internal Medicine (n = 20; 30.3%) was the most addressed field. Most systematic reviews (n = 46; 69.7%) were rated as being of "critically low-quality".
    CONCLUSIONS: There were consistent flaws in the methodological quality report of the systematic reviews included, particularly in establishing a prior protocol and not assessing the potential impact of the risk of bias on the results. Through the years, the number of systematic reviews published increased, yet their quality is suboptimal. There is a need to improve the reporting of systematic reviews in Portuguese medical journals, which can be achieved by better adherence to quality checklists/tools.
    Keywords:  AMSTAR-2; Meta-analysis; Portugal; Quality; Systematic review
    DOI:  https://doi.org/10.1186/s12874-022-01591-z
  34. Health Res Policy Syst. 2022 Apr 12. 20(1): 39
       BACKGROUND: In light of replication and translational failures, biomedical research practices have recently come under scrutiny. Experts have pointed out that the current incentive structures at research institutions do not sufficiently incentivise researchers to invest in robustness and transparency and instead incentivise them to optimize their fitness in the struggle for publications and grants. This cross-sectional study aimed to describe whether and how relevant policies of university medical centres in Germany support the robust and transparent conduct of research and how prevalent traditional metrics are.
    METHODS: For 38 German university medical centres, we searched for institutional policies for academic degrees and academic appointments as well as websites for their core facilities and research in general between December 2020 and February 2021. We screened the documents for mentions of indicators of robust and transparent research (study registration; reporting of results; sharing of research data, code and protocols; open access; and measures to increase robustness) and for mentions of more traditional metrics of career progression (number of publications; number and value of awarded grants; impact factors; and authorship order).
    RESULTS: While open access was mentioned in 16% of PhD regulations, other indicators of robust and transparent research were mentioned in less than 10% of institutional policies for academic degrees and academic appointments. These indicators were more frequently mentioned on the core facility and general research websites. Institutional policies for academic degrees and academic appointments had frequent mentions of traditional metrics.
    CONCLUSIONS: References to robust and transparent research practices are, with a few exceptions, generally uncommon in institutional policies at German university medical centres, while traditional criteria for academic promotion and tenure still prevail.
    Keywords:  Incentives; Open science; Robustness; Science policy; Transparency; University medical centre
    DOI:  https://doi.org/10.1186/s12961-022-00841-2
  35. J Contemp Psychother. 2022 Apr 06. 1-10
      The Psyche Awards were developed to recognize the best journal articles published during the previous year. Each award confronts a specific topic within the field of mental health care, identifying articles that integrate the science and practice of psychology. For the current awards, 161 journals were screened, and 223 relevant articles were identified. The papers were then narrowed down to 46 papers distributed across 11 award categories. A panel of four expert judges read each article and rated all papers for their contribution to the field. The current award categories highlight some of the best articles published during 2021, capturing important information about psychological assessment, treatment of depression, working with suicidal clients, technology-assisted psychotherapy, the impact of Covid-19 on mental health, lessons from a review of history, recent innovations in the field, and strategies to expand the integration of science and practice.
    Keywords:  Professional development; Psychotherapy outcome; Psychotherapy process
    DOI:  https://doi.org/10.1007/s10879-022-09540-z
  36. Ann Palliat Med. 2022 Mar 22. pii: apm-21-2645. [Epub ahead of print]
      Takotsubo cardiomyopathy (TTC) is often acute with a high mortality rate and is subject to relapse. Meanwhile, its complex pathogenesis has attracted increasing attention. To learn more about TTC, CiteSpace V.5.7 R5W was used in this study to analyze the research status, hot spots, and trends in TTC before 2020. The keywords, co-citation references, as well as country and institution distribution were explored. A total of 2,349 papers were reviewed. The United States, Italy, and Germany were the main countries studying TTC and had good cooperation relationships. The Mayo Clinic topped the institution list, but the rate of inter-institutional cooperation was not high. Research hotspots include disease features, auxiliary diagnostic methods, epidemiology, and pathophysiological mechanisms, and the latest ones are complications related to prognosis, such as cardiovascular abnormalities caused by myocardial infarction and normal or non-obstructive coronary arteries (MINOCA), atrial fibrillation, stroke, cancer, and COVID-19. In conclusion, the research of TTC is in a hot development period. Our research will help clinicians and researchers to better understand TTC and its research status by providing a foundation for research objectives. In doing this, our research will help to provide better scientific management, diagnosis, and treatment for patients with TTC, which will in turn improve the prognosis of this condition.
    Keywords:  CiteSpace; Takotsubo cardiomyopathy (TTC); emerging trends; knowledge domain; scientometric review
    DOI:  https://doi.org/10.21037/apm-21-2645
  37. Res Involv Engagem. 2022 Apr 11. 8(1): 12
       BACKGROUND: Patient advocates are increasingly authoring peer-reviewed publications that could enhance patient care and understanding of the lived experience. Although patient authorship may be seen as an innovation in the peer-reviewed publication environment and some may not be aware of or accept patient authorship, we know patient-authored publications exist. However, identifying patient-authored publications is often challenging and time-consuming.
    MAIN BODY: In this commentary, we propose a definition for a patient author and patient-authored publications. We outline factors driving the increase in patient authorship, including patient interest, recognition of the value of including the patient voice and major funders recognising the importance of involving patient advocates in research. Evidence and experience-based guidance on patient authorship is emerging, and we highlight practical guidance for patient advocates on authoring peer-reviewed publications. To gain a better understanding of patient authorship, an efficient method is needed to identify patient-authored publications. A dataset on patient-authored publications could be used for a range of quantitative and qualitative research studies. The affiliation search function in PubMed can provide an easy, and reproducible way to identify a dataset of patient-authored publications in the international peer-reviewed literature, but only if patient authors include a standard metatag, (e.g. Patient Author) as one of their listed affiliations, combined with other affiliations as appropriate. From 2020 to 2021, there was a nine-fold increase in patient-authored publications in PubMed identified using the Patient Author tag. We recognize that terminology can be contentious and some authors may prefer alternative metatags. Further efforts are required to gain consensus on a suitable, standard metatag or set of metatags to use to show the true extent of patient authorship.
    CONCLUSION: Patient authorship is not only legitimate, but it also exemplifies the principles of diversity, equity and inclusion. Stakeholders in the publication community need to review their policies and procedures to identify and address barriers to patient authorship. Patient advocates, funders, researchers and publishers could all help to promote awareness and acceptance of patient authorship and the merits of using a standard metatag or set of metatags, so that patient-authored publications are no longer hidden in plain sight.
    Keywords:  Authorship; Diversity; Equity and inclusion; Patient and public involvement; Patient author; PubMed; Publications
    DOI:  https://doi.org/10.1186/s40900-022-00346-w