bims-evares Biomed News
on Evaluation of research
Issue of 2022–01–09
thirty-six papers selected by
Thomas Krichel, Open Library Society
  1. Study on Pain Catastrophizing From 2010 to 2020: A Bibliometric Analysis via CiteSpace.
  2. Top-100 Most-Cited Sports-Related Concussion Articles Focus on Symptomatology, Epidemiology, and Demographics.
  3. The 50 Most Cited Articles on Meniscus Injuries and Surgery from 2000 to 2019 Focus on Arthroscopic Repair or Removal, Originate from Institutions Within the United States and Were Published Before 2010.
  4. 50 years in urinary incontinence: a bibliometric analysis of the top 100 cited articles of the last 50 years.
  5. Global trends of machine learning applications in psychiatric research over 30 years: A bibliometric analysis.
  6. Top 100 cited articles in one year of COVID-19 research - A bibliometric analysis.
  7. A bibliometric analysis of infectious diseases in patients with liver transplantation in the last decade.
  8. Research Status Quo in Traditional Mongolian Medicine: A Bibliometric Analysis on Research Documents in the Web of Science Database.
  9. Research development and trends of benzene-induced leukemia from 1990 to 2019-A bibliometric analysis.
  10. Authorship Gender Composition in Urology Literature from 2015 through 2020.
  11. Global research trends in perioperative care for the elderly: a bibliometric and visualized study.
  12. Review of authorship for COVID-19 research conducted during the 2020 first-wave epidemic in Africa reveals emergence of promising African biomedical research and persisting asymmetry of international collaborations.
  13. Health-related research publications on religious mass gatherings of Muslims: a bibliometric analysis (1980-2020).
  14. Ten Years of Publications: Scientometric comparison of major Neurosurgical Journals.
  15. Ophthalmic trauma: the top 100 cited articles in Ophthalmology journals.
  16. Global analysis of the COVID-19 research landscape and scientific impact.
  17. Redefining the Gender Gap in Urology Authorship: An 18-Year Publication Analysis.
  18. How digital marketing evolved over time: A bibliometric analysis on scopus database.
  19. Bibliometric analysis of cancer care operations management: current status, developments, and future directions.
  20. Intersectional inequalities in science.
  21. Research challenges and opportunities in the Caribbean area: first bibliometric study in the French West Indies, from 1989 to 2018.
  22. Relationships Between Obstructive Sleep Apnea and Cardiovascular Disease: A Bibliometric Analysis (2010-2021).
  23. [Hotspots and trends of Ophiopogonis Radix based on CiteSpace knowledge map].
  24. Orthopaedic Foot and Ankle Surgery Fellowship Directors Are Typically White Men in Their Early 50s With Strong Achievements in Research.
  25. Publication rate and evidence-based evaluation of abstracts presented at the veterinary endoscopy society annual meeting (2004-2019).
  26. Influential methods reports for group-randomized trials and related designs.
  27. Global cervical cancer research: A scientometric density equalizing mapping and socioeconomic analysis.
  28. The characteristics of early-stage research into human genes are substantially different from subsequent research.
  29. Key performance indicators of Russian universities for 2015-2018: Dataset and Benchmarking Data.
  30. Applications of Artificial Intelligence in Non-cardiac Vascular Diseases: A Bibliographic Analysis.
  31. Diversity in Psychological Research Activities: Quantitative Approach With Topic Modeling.
  32. National Trends of Gender Disparity in Canadian Cardiovascular Society Guideline Authors, 2001-2020.
  33. Progress in the interaction of dissolved organic matter and microbes (1991-2020): a bibliometric review.
  34. Gender Disparities Among Highly Cited Researchers in Biomedicine, 2014-2020.
  35. Firearm-related research articles in health sciences by funding status and type: A scoping review.
  36. Mapping 2 Decades of Research in Health Services Research, Health Policy, and Health Economics Journals.
  1. Front Psychol. 2021 ;12 759347
    Study on Pain Catastrophizing From 2010 to 2020: A Bibliometric Analysis via CiteSpace.
    Huifang Luo, Zongliao Cai, Yanyi Huang, Jiating Song, Qing Ma, Xiangwei Yang, Yang Song.
      Purpose: This study aimed to evaluate the global scientific output of research on pain catastrophizing and explore the hotspots and frontiers from 2010 to 2020 using bibliometric methods. Methods: Publications regarding pain catastrophizing published from 2010 to 2020 were extracted from the Web of Science Core Collection. CiteSpace was used to analyze the number of publications, countries, institutions, journals, authors, cited references, and keywords using standard bibliometric indicators. Results: A total of 1,576 publications on pain catastrophizing were retrieved from 2010 to December 31, 2020. The number and rate of the annual publications gradually increased totally. Pain (130) was the most productive journal. Meanwhile, Pain ranked first in the frequency (1,432) and centrality (0.31) of the cited journals. The most productive country and institution in this frequency field were the United States (642) and the University of Washington (73), respectively. Jensen MP (34) was the most prolific author, and Sullivan MJL (1,196) ranked first among the cited authors. In the ranking of frequency in the cited references, the first article was a critical review about pain catastrophizing published by Quartana (100). The keyword "Low back pain" had the highest frequency (556). "Total hip" was identified as a frontier research item for 2016-2020. Conclusion: The findings of this bibliometric study provide the current status and trends in the clinical research of pain catastrophizing and may help researchers to identify hot topics and explore new research directions in this field.
    Keywords:  CiteSpace; Web of Science; bibliometric analysis; pain catastrophizing; research trends
    DOI:  https://doi.org/10.3389/fpsyg.2021.759347
  2. Arthrosc Sports Med Rehabil. 2021 Dec;3(6): e1585-e1597
    Top-100 Most-Cited Sports-Related Concussion Articles Focus on Symptomatology, Epidemiology, and Demographics.
    Kade S McQuivey, M Lane Moore, Jordan R Pollock, Jeffrey D Hassebrock, Karan A Patel, Anikar Chhabra.
       Purpose: To analyze the top-100 cited articles on sports-related concussions together with a bibliometric analysis to determine citations by year, level of evidence, study design, and several other factors related to the top referenced articles in sports concussions.
    Methods: The Clarivate Analytics Web of Knowledge database was used to gather data using Boolean queries to capture all possible iterations of sports-related concussion research. Articles were organized in descending order based on the number of citations and included or excluded based on relevance to concussion. Collected information included author name, publication year, country of origin, journal name, article type, study focus, and the level of evidence.
    Results: The top-100 articles were cited 31,197 times with an average of 312.0 citations per publication. More than one half were published in 2006 or later (52). Cohort studies and descriptive articles were the most prevalent study types (22 each). Studies with Level V evidence were the most common (33). The most common areas of study were symptomatology (short term, long term) with 17 articles, followed by epidemiology/demographics with 16 articles. The least common area of study was concussion prevention (2 articles), followed by management/treatment, diagnostics (labs, imaging) with 4 articles each.
    Conclusions: We identified the most influential studies in sports-related concussion based on number of citations and citation density. A majority of these articles were published in the United States after 2006 and are most commonly cohort studies (Level IV evidence) and descriptive articles (Level V evidence). Current research focuses most heavily on the symptomatology and epidemiology/demographics of sports concussion.
    Clinical Relevance: This study serves to identify the most influential articles in sports-related concussion and identify research topics with general deficiencies within the field of sports-related concussion research.
    DOI:  https://doi.org/10.1016/j.asmr.2021.06.016
  3. Arthrosc Sports Med Rehabil. 2021 Dec;3(6): e2103-e2116
    The 50 Most Cited Articles on Meniscus Injuries and Surgery from 2000 to 2019 Focus on Arthroscopic Repair or Removal, Originate from Institutions Within the United States and Were Published Before 2010.
    Alyssa C Brown, Phara P Ross, Symone M Brown, Mary K Mulcahey.
       Purpose: To identify the 50 most cited original articles on meniscus injury and surgery from 2000 to 2019, and to perform a bibliometric analysis of the identified articles.
    Methods: A Clarivate Web of Science search, completed in June 2020, generated a list of the most cited articles related to meniscus research. Articles were sorted by number of times cited, and review articles or those unrelated to the meniscus were removed. Articles were classified as basic science or assigned the appropriate level of evidence. Extracted data included title, authors, journal, year of publication, country/institution of origin, total number of citations, and number of citations per year.
    Results: The final list of 50 included articles with a range of 106 to 490 citations and a mean of 162.34 total or 11.91 citations per year. The most cited articles appeared in 8 of the most influential journals in the field per the Journal Citation Index. Twenty-nine (58%) originated from institutions within the United States, and only 13 (26%) were published in 2010 or later. Overall, 25 (50%) were classified as therapeutic, only 5 (10%) were therapeutic randomized controlled studies, and 17 (34%) were basic science. "Arthroscopic meniscal repair or meniscectomy" appeared most frequently, with 16 (32%) falling into this subclassification.
    Conclusion: This study of the most cited meniscus articles showed a strong predominance for therapeutic studies, studies generated and published within the United States, and studies focused on topics of arthroscopic repair or removal. Overwhelmingly, included articles were published before 2010, affirming the criticism that bibliometric analysis favors older articles.
    Clinical relevance: This study provides information about which articles are driving the field relating to meniscus injuries and meniscus surgery in the last two decades.
    DOI:  https://doi.org/10.1016/j.asmr.2021.09.013
  4. Int Urogynecol J. 2022 Jan 03.
    50 years in urinary incontinence: a bibliometric analysis of the top 100 cited articles of the last 50 years.
    I Mahamud, Anna Mainwaring.
       INTRODUCTION: A large body of literature has been published on urinary incontinence, ranging from medical treatment, epidemiology and surgical techniques. A bibliometric analysis is used to identify high-quality research papers using criteria such as citation rate and journal impact factor.
    OBJECTIVES: To describe key themes and topics in urinary incontinence literature in the last 50 years.
    METHODS: Thomson Reuters Web of Science citation indexing database was used to identify the top 100 cited articles in urinary incontinence in the last 50 years. Data sets were subdivided into manuscript type, theme, author, institution, country of origin, journal and citation rate.
    RESULTS: Mean number of citations in the top 100 group for manuscripts was 676, ranging between 2444 and 306. Most cited paper was by Irwin et al. The manuscript with the highest citation rate was by Dumoulin et al., citation rate of 470.7/year. The largest number of manuscripts was published between 2000 and 2009 (n = 47). The New England Journal of Medicine (NEJM) had the highest impact factor (74.67) and five manuscripts were published in this journal. Fifty-seven per cent of articles were published in journals with impact factor < 5. The vast majority of the articles focussed on epidemiology, followed by surgical treatment of urinary incontinence, 69% being original research studies.
    CONCLUSION: This is the first bibliometric analysis of the top 100 most influential papers in urinary incontinence. The key themes identified were epidemiology and surgical management, with most papers being original research studies.
    Keywords:  Bibliometric analysis; Epidemiology; Literature review; Urinary incontinence
    DOI:  https://doi.org/10.1007/s00192-021-05039-8
  5. Asian J Psychiatr. 2021 Dec 30. pii: S1876-2018(21)00442-1. [Epub ahead of print]69 102986
    Global trends of machine learning applications in psychiatric research over 30 years: A bibliometric analysis.
    Anuradha Baminiwatta.
      This bibliometric analysis aimed to identify active research areas and trends in machine learning applications within the psychiatric literature. An exponential growth in the number of related publications indexed in Web of Science during the last decade was noted. Document co-citation analysis revealed 10 clusters of knowledge, which included several mental health conditions, albeit with visible structural overlap. Several influential publications in the co-citation network were identified. Keyword trends illustrated a recent shift of focus from "psychotic" to "neurotic" conditions. Despite a relative lack of literature from the developing world, a recent rise in publications from Asian countries was observed. DATA AVAILABILITY: Bibliographic data for this study were downloaded from the Web of Science. The search strategy is included in the Supplementary file.
    Keywords:  Artificial intelligence; Bibliometrics; Machine learning; Mental health; Psychiatry; Trends
    DOI:  https://doi.org/10.1016/j.ajp.2021.102986
  6. Indian J Public Health. 2021 Oct-Dec;65(4):65(4): 375-379
    Top 100 cited articles in one year of COVID-19 research - A bibliometric analysis.
    Ragul Ganesh, Karthikeyan Mahalingam, N Kandaswamy, Chandradevi Shanmugam, Venugopalan Y Vishnu, Arunkumar Subbiah.
       Background: Coronavirus disease (COVID-19)-related scientific publications have increased exponentially during the present pandemic but their influence on biomedical literature is not known. The characteristics of highly cited articles help us to identify important advances and their scientific impact.
    Objectives: In the present study, we have identified and analyzed the top 100 most highly-cited articles of COVID-19 research published in the year 2020.
    Methods: A cross-sectional bibliometric analysis was using the search terms "severe acute respiratory syndrome-coronavirus-2," "COVID," "nCoV," "Coronavirus," and "HCoV" querying the Google Scholar database using the program "Publish or Perish." The first 100 English language articles with the maximum number of citations were identified and evaluated in detail.
    Results: The top 100 COVID-19 articles in 2020 had citations ranging from 1147 to 20,440. The median (interquartile range [IQR]) number of citations was 1970 (1456-2939). The number of authors ranged from 1 to 79 (median 10; IQR 5.25-19). The majority of first authors was from China (58%), followed by the United States of America (16%) and the United Kingdom (7%). The top three journals in terms of the number of published articles (37%) were the New England Journal of Medicine, Journal of the American Medical Association, and The Lancet. Most of the top-cited COVID-19 literature were descriptive studies focusing on epidemiology (48%) and clinical course (60%) of COVID-19.
    Conclusion: Clinical course and epidemiology have been the predominant areas of research interest in COVID-19 in 2020. Citation analysis of COVID-19 literature helps us to map out the most important focus for research in this pandemic and to identify gaps in knowledge which would guide further research.
    Keywords:  Bibliometric analysis; COVID-19; coronavirus; severe acute respiratory syndrome coronavirus-2
    DOI:  https://doi.org/10.4103/ijph.ijph_1133_21
  7. Ann Transl Med. 2021 Nov;9(22): 1646
    A bibliometric analysis of infectious diseases in patients with liver transplantation in the last decade.
    Han Zhong, Chun-Yan Liu, You-Qin Dai, Cheng Zhu, Ke-Jia Le, Xiao-Yun Pang, Yu-Jie Li, Zhi-Chun Gu, Yue-Tian Yu.
       Background: A bibliometric analysis was performed to reveal the current status of investigations in infectious diseases in patients with liver transplantation (LT) and to prioritize future research needs.
    Methods: The present study comprehensively retrieved publications relevant to infectious diseases in LT recipients published between 2010 and 2020. The search was conducted on the Web of Science (WoS) database. A bibliometric analysis was conducted through machine learning and visualization tools, including VOSviewer, Bibliographic Item Co-Occurrence Matrix Builder, and Graphical Clustering Toolkit. Research hotspots and trends in the field were assessed, while the contributions and collaborations of countries, institutions, and authors were documented.
    Results: A total of 691 publications were analyzed. Research output sharply increased in 2015, with a fast drop afterward. "Liver transplantation" was the most frequent keyword, with strong links to "hepatitis C virus" and "infection". Study areas included risk factors of infectious diseases in LT recipients, pathogens causing post-transplantation infections, antibacterial therapy and prophylaxis for peritransplant infection complications, living donor LT, and pediatric LT. The efficacy and safety of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) infection among liver transplant recipients has attracted recent research interest. Didier Samuel was the most productive author, while Xavier Forns was the top-cited author. Shanghai Jiao Tong University was the most productive contributor, and Gilead Sciences was the most cited organization. Moreover, the USA was the greatest contributor. Gastroenterology was the most cited journal, while Liver Transplantation was the most prolific journal.
    Conclusions: This bibliometric analysis will better understand the research status of infectious complications in LT recipients and forecast future research trends. Priority should be given to identifying risk factors for peritransplantation infections and effective treatments against infectious complications in the coming years.
    Keywords:  Infectious disease; bibliometric analysis; hotspots; liver transplantation (LT); trends
    DOI:  https://doi.org/10.21037/atm-21-2388
  8. Evid Based Complement Alternat Med. 2021 ;2021 5088129
    Research Status Quo in Traditional Mongolian Medicine: A Bibliometric Analysis on Research Documents in the Web of Science Database.
    Tae-Hun Kim, Jung Won Kang.
       Objective: In this study, the current state of research on traditional Mongolian medicine (TMM) through a bibliometric analysis of research documents located in the Web of Science (WoS) database was assessed.
    Methods: The WoS database was searched on September 2021 with the keywords "traditional Mongolian medicine." Publications on TMM scientific research were included in this study, without any language limitations. Bibliometric data from such publications were retrieved from the WoS database. Full records with cited reference lists were descriptively analyzed. To assess trends in TMM research topics, authors' keywords were analyzed. A thematic evolution map based on coword analysis was suggested. To analyze research networks among co-authors, affiliations, or countries of the authors, collaboration networks were evaluated. The Bibliometrix R package (3.1) was used for the analysis.
    Results: A total of 234 scientific publications were included in the analysis. The top three countries of origin of the corresponding authors were China (n = 153), Japan (n = 28), and South Korea (n = 9). The top three relevant affiliations of the authors in the included publications were "Inner Mongolia Medical University," "Inner Mongolia University of Nationalities," and "National University of Mongolia." "Flavonoids," "cytotoxicity," "NMR," and "Tibetan medicine" were the most frequently used keywords in the included documents. Most publications focused on the chemical analysis and mechanism of effects of Mongolian herbal medications. There were few publications on nonpharmacological interventions such as bloodletting or TMM diagnostics, which should be promoted in future publications.
    Conclusion: There were only a limited number of publications on TMM identified through a search of the WoS database, using the keywords "Traditional Mongolian medicine." More improved strategy for searching for TMM publications must be established. Research publications on TMM, especially regarding nonpharmacological interventions, need to be promoted. In addition, collaboration with researchers worldwide needs to be encouraged in the future.
    DOI:  https://doi.org/10.1155/2021/5088129
  9. Environ Sci Pollut Res Int. 2022 Jan 08.
    Research development and trends of benzene-induced leukemia from 1990 to 2019-A bibliometric analysis.
    Qianyu Sun, Boshen Wang, Shouxiang Xu, Xiaowei Cong, Yuepu Pu, Juan Zhang.
      Benzene is an occupational and environmental toxicant, causing hematopoietic damage. Our study is aimed to extract the trend of benzene-induced leukemia (BIL) and qualitatively and quantitatively estimate research on it. Publications on BIL were identified from the Web of Science Core Collection (WoSCC). Microsoft Excel 2019 (Redmond, WA) and The CiteSpace 5.6.R5 software (Drexel University, Philadelphia, PA) were used to analyze the publication outcomes, countries, institutions, authors, keywords, and research frontiers. The overall 1152 publications were collected from 1990 to 2019 until November 6, 2020. Environ Health Persp had the highest number of articles published. The USA were the top country in terms of BIL. The Smith MT, Yin SN, Lan Q, and Hayes RB are both listed in the top 10 of co-cited authors, high contribution authors, and the authors of co-cited references. High IF articles account for a considerable proportion, among all the publications. Chinese institutions engaged in BIL and contributed a large part of articles. Exposure population, exposure dose, and exposure risk are the research hotspots in this field. The risk of benzene exposure on childhood leukemia is at issue, and the studies on attributable risk of benzene-induced leukemia are few. More early, sensitive, and specific epigenetic biomarkers of benzolism may be the leading research fields of benzene-induced leukemia in the next few years.
    Keywords:  Benzene; Bibliometric; CiteSpace; Leukemia; Research frontier; Web of Science
    DOI:  https://doi.org/10.1007/s11356-021-17432-3
  10. Urology. 2022 Jan 04. pii: S0090-4295(21)01199-7. [Epub ahead of print]
    Authorship Gender Composition in Urology Literature from 2015 through 2020.
    María Camila Suárez Arbeláez, Daniel E Nassau, Manish Kuchakulla, Arjun Watane, Aayush Shah, Meghana Kalavar, Jesse Ory, Ranjith Ramasamy.
       OBJECTIVE: To describe the current landscape of first and last female authorship in urology journals relative to the journals' impact factor. We hypothesized that women would have a smaller proportion of publications in journals with higher impact factors.
    METHODS: Eighteen urology journals were divided into groups based on impact factor accordingly: from 33.2 to 6.2 were classified as high (European Urology, Nature Reviews Urology, The Journal of Urology, BJU International, Prostate Cancer and Prostatic Diseases, and The Journal of Sexual Medicine), from 5.8 to 5.0 as medium (Asian Journal of Andrology, European Urology Focus, Sexual Medicine Reviews, Bladder Cancer, Prostate and World Journal of Urology), and from 4.8 to 2.2 as low (Urologic Oncology, Journal of Endourology, Neurourology and Urodynamics, Urology, Journal of Pediatric Urology and Female Pelvic Medicine & Reconstructive Surgery). A computer script was designed using Python™ to search PubMed® and record first and last author of publications between 2015-2020. Gender was determined by Gender-Api (https://gender-api.com). Names with an accuracy of <90% were excluded. Type of peer-review and scope of each journal were also analyzed. Statistical analysis was performed using Matlab.
    RESULTS: A total of 37,413 first and 28,414 last authors were identified during the study period. Overall, women represented 21% (8,029/37,413) of first and 15% (4,232/28,414) of last authors. Women were significantly less published in high impact journals compared to both medium and low impact journals (p<.001 in all). Among all journals, articles with female first authors were more likely to have a female last author (OR: 2.72, CI: 2.5-2.9, p<.001). Subspecialty journals had more female last authors than general journals (p<.05), and female representation increased if reviews were double-blinded (p<.001). Over the last 6 years, there has been a significant increase in female senior authorship among all journals (p=.045).
    CONCLUSIONS: The proportion of female authorship was significantly lower in higher impact urology journals. While the underlying cause is likely multifactorial, this finding highlights a gender discrepancy that may impact women's ability to achieve career goals in academic medicine when compared to their male counterparts.
    Keywords:  Gender disparity; authorship; impact factor, urology; publications
    DOI:  https://doi.org/10.1016/j.urology.2021.11.041
  11. J Anesth. 2022 Jan 07.
    Global research trends in perioperative care for the elderly: a bibliometric and visualized study.
    Qinghua Chen, Ya Wang, Shengwen Song, Guohao Xie, Baoli Cheng, Xiangming Fang.
       PURPOSE: Aged surgical patients are at a relatively higher risk of morbidity and mortality than younger surgical patients. The present study aimed to investigate the trends and research status of perioperative care for the elderly in the anesthesiology field.
    METHODS: We screened manuscripts published between May 31, 1991, and May 31, 2020, from the Web of Science Core Collection (WoSCC). A clustered network was derived from all references cited in all of the included manuscripts. The top authors, journals, institutions, countries, keywords, co-cited articles, and trends were identified through bibliometric analysis and visualization using CiteSpace 5.8.R3 and VOSviewer 1.6.15.
    RESULTS: We included a total of 1860 manuscripts published between 1991 and 2020. The number of publications on perioperative care for the elderly sharply increased from 2014 onwards. The United States of America and the University of California, San Francisco were the leading publication country (24.8%, 461/1860) and institution (2.6%, 48/1860), respectively. High-frequency keywords in cluster analysis included the type of anesthesia, postoperative pain management, postoperative cognitive dysfunction, and postoperative delirium, indicating postoperative cognitive dysfunction and postoperative delirium remain the focus areas for research in perioperative care for the elderly. Organ function protection was the new research focus according to the burst detection analysis of top keywords.
    CONCLUSIONS: The number of studies on perioperative care for the elderly has increased apparently worldwide. Postoperative cognitive dysfunction and postoperative delirium remain primary research focus areas. Organ function protection appears to be the second most highly researched topic in the perioperative care for the elderly.
    Keywords:  Bibliometric analysis; Elderly; Global trends; Perioperative care; Visualized analysis
    DOI:  https://doi.org/10.1007/s00540-021-03033-4
  12. Trop Med Int Health. 2022 Jan 05.
    Review of authorship for COVID-19 research conducted during the 2020 first-wave epidemic in Africa reveals emergence of promising African biomedical research and persisting asymmetry of international collaborations.
    Serge Tonen-Wolyec, Dieu-Merci Mbumba Lupaka, Salomon Batina-Agasa, François-Xavier Mbopi Keou, Laurent Bélec.
       OBJECTIVE: The contribution of African authors to the biomedical literature is small. We evaluated the African and non-African scientific production published in the international literature on the COVID-19 in Africa during the first year of the epidemic (2020).
    METHODS: Papers on COVID-19 in Africa were extracted from the Medline (Pubmed) database for bibliometric analysis including the proportions of three leading and last authors by study type, study country, authors' and laboratories/institutions' countries of affiliation, and journal ranking.
    RESULTS: A total of 160 articles fulfilling the inclusion criteria was analyzed. The majority (91.3%) was produced by half (53.7%) of African countries, with important regional disparities, and generally without sources of funding mentioned. The majority (>85.0) of authors in lead positions (first, second, third, and last authors) were Africans. Only a small number (8.7%) of studies on COVID-19 in Africa were carried out by laboratories not on the African continent (mainly Europe, USA and China) and generally received funding. The last and first authors were more frequently of non-African origin in journals with an Impact Factor ranking ≥1, and more frequently of African origin in journals with a lower ranking (< 1). The first and last non-African authors tended to report their studies in high-ranking ≥1 journals.
    CONCLUSIONS: Our study demonstrates the emergence of promising African research capable of publishing in indexed but low-impact factor medical journals and reveals the persistence of a North-South asymmetry in international cooperation in biomedical research with Africa.
    Keywords:  Bibliometry; COVID-19; Leadership; Medical research; Sub-Saharan Africa
    DOI:  https://doi.org/10.1111/tmi.13717
  13. Trop Dis Travel Med Vaccines. 2022 Jan 04. 8(1): 1
    Health-related research publications on religious mass gatherings of Muslims: a bibliometric analysis (1980-2020).
    Waleed M Sweileh.
       OBJECTIVE: Mass gatherings medicine is an emerging and important field at the national and international health security levels. The objective of the current study was to analyze research publications on religious mass gatherings of Muslims using bibliometric tools.
    METHODS: Keywords related to religious mass gatherings of Muslims were used in Scopus database. The duration of the study was from January 01, 1980 to December 31, 2020. Examples of keywords used include hajj, Umrah, mass gatherings/Mecca or Makkah, mass gatherings/Karbala, pilgrim/Makkah or Mecca, and others. Bibliometric indicators and mapping were presented.
    RESULTS: In total, 509 documents were retrieved. The average number of citations per article was 16.7 per document. Analysis of the retrieved documents indicated that (1) more than 90% of the retrieved documents were about the mass gatherings in Mecca/Makkah; (2) two-thirds of the retrieved documents were research articles; (3) a take-off phase in the number of publications was observed after 2008; (4) the retrieved documents were disseminated in a wide range of journals but specifically the ones in the fields of infectious diseases, public health, and travel medicine; (5) the retrieved documents were mainly published by scholars from Saudi Arabia with collaborative research ties with scholars in the US, France, the UK, and Australia; (6) Saudi Arabia contributed to more than half of the retrieved documents; and (7) four research themes were found: knowledge, attitude, and practices of pilgrims to Mecca/Makkah, vaccination, etiology of hospital admission among pilgrims, and epidemiology of various types of infectious diseases.
    CONCLUSIONS: Research on mass gatherings, specifically the Hajj, is emerging. Researchers from the Saudi Arabia dominated the field. Research collaboration between scholars in Saudi Arabia and scholars in low- and middle-income countries is needed and must be encouraged since these countries have weaker health systems to screen, monitor, and control the spread of infectious diseases because of the Hajj season.
    Keywords:  Bibliometrics; Islam; Religious mass gatherings; Saudi Arabia; Travel medicine
    DOI:  https://doi.org/10.1186/s40794-021-00158-y
  14. World Neurosurg. 2021 Dec 29. pii: S1878-8750(21)01940-9. [Epub ahead of print]
    Ten Years of Publications: Scientometric comparison of major Neurosurgical Journals.
    Kanwaljeet Garg, Edoardo Agosti, Bipin Chaurasia, Marco M Fontanella.
       BACKGROUND: The goal of this study was to examine neurosurgical scientific publications and change in the trends in major neurosurgical journals during the last 10 years.
    METHODS: The peer-reviewed articles published in 12 prominent neurosurgical Journals over the last 10 years were analyzed. The journals were grouped into two groups based on the number of articles published in a journal in a year (> / = 500 or < 500).
    RESULTS: The total number of peer-reviewed articles published in 10 years in these 12 journals was 48,957. The number of peer-reviewed articles published in a year increased from 3,441 to 7,316 over this time. The maximum number of peer-reviewed articles were published in 2019 in Group A (n = 7,170) and in 2018 in Group B journals (n = 615). The commonest article type was Original articles and Case reports in both the groups, but the proportion of original articles published was higher in Group A journals (54.0%) as compared to Group B journals (44.5%). Review articles were more commonly published in Group B. The proportion of articles published in Group A and B journals from the USA was 48.0% and 31.7% respectively, while the proportion of articles from Europe was 21.4% and 36.2%, respectively.
    CONCLUSION: Neurosurgical publications are continuously increasing, with a parallel growth in the number of authors and citations all over the world. There are significant differences in the scientometric indices of major neurosurgical journals based on their yearly articles published.
    Keywords:  Bibliometric; Neurosurgery; Scientometric
    DOI:  https://doi.org/10.1016/j.wneu.2021.12.095
  15. Eye (Lond). 2022 Jan 03.
    Ophthalmic trauma: the top 100 cited articles in Ophthalmology journals.
    Alex T Pham, Todd D Whitescarver, Bradley Beatson, Boonkit Purt, Yoshihiro Yonekawa, Ankoor S Shah, Marcus H Colyer, Fasika A Woreta, Grant A Justin.
       OBJECTIVES: To analyze the top 100 cited papers on ophthalmic trauma.
    METHODS: A literature search of Ophthalmology journals within the ISI Web of Science database for the most cited papers related to ophthalmic trauma.
    RESULTS: The most cited articles were published between 1943 and 2013, the greatest number being published in 2000. Ophthalmology (45), Archives of Ophthalmology (17), and the American Journal of Ophthalmology (15) published most of the articles. The institutions with the highest number of publications were Wilmer Eye Institute (10) and Massachusetts Eye and Ear Infirmary (7). Sixty-seven percent of the articles originated from the USA. The most common type of trauma studied was non-open-globe injuries and the most frequent topic studied were pathological conditions secondary to trauma (34), particularly endophthalmitis (8), and optic neuropathy (6). Articles presenting a standardized classification system for eye injury received the highest average of citations per publication. Types of research most frequently cited were observational clinical studies (62) and epidemiological studies (30); the least frequent were clinical trials (2).
    CONCLUSION: This bibliographic study provides a historical perspective of the literature and identifies trends within the most highly influential papers on ophthalmic trauma. Many of these articles emerged within the past three decades and came from Ophthalmology journals that remain high impact to this day. Clinical trials have been difficult to conduct and are lacking, reflecting a critical need in ophthalmic trauma research, as most of our understanding of ophthalmic trauma comes from observational and epidemiological studies.
    DOI:  https://doi.org/10.1038/s41433-021-01871-w
  16. Am J Infect Control. 2022 Jan 02. pii: S0196-6553(21)00865-8. [Epub ahead of print]
    Global analysis of the COVID-19 research landscape and scientific impact.
    Ying Chen, Shixiang Chen, Bingxin Ma, Zhaoxia Duan, Jin Yang, Yulu Wang, Xiaojun Zhang, Yaqi Huang, Yanwen Zhang, Cuiyu Deng, Qi Lu, Yaogang Wang, Yue Zhao.
       OBJECTIVES: To consider a one-year time window of the COVID-19 crisis to integrate qualitative and quantitative data and provide an in-depth analysis of all COVID-19 publications from geographical, epidemiological and chronological perspectives.
    METHODS: Publications on COVID-19 from December 1, 2019, to December 31, 2020 without document type limitations were extracted from the Web of Science database. Microsoft Excel 2016, GraphPad Prism 9, VOSviewer 1.6.15 and IBM SPSS 21.0 were used to analyze the global epidemiological publication landscape and its correlations, research hotspots around the world and the top 5 countries in terms of publications.
    RESULTS: A total of 51,317 documents were analyzed in the present study. The publication trend could be divided into an increasing output stage and an explosive output stage. There were positive correlations between monthly publications, confirmed cases and deaths. Research hotspots from the whole year, from individual quarters, and from the top 5 countries with the most publications were further identified.
    CONCLUSIONS: The correlation analysis of publications indicated that confirmed cases and deaths were forces driving the scientific output, reflecting the growing trend to some extent. Moreover, the hotspot analysis provided valuable information for scientists, funders, policy and decision-makers to determine what areas should be their focus when faced with public health emergencies in the future.
    Keywords:  Bibliometric; COVID-19; Keyword co-occurrence; Research landscape
    DOI:  https://doi.org/10.1016/j.ajic.2021.12.025
  17. Eur Urol Focus. 2021 Dec 30. pii: S2405-4569(21)00311-4. [Epub ahead of print]
    Redefining the Gender Gap in Urology Authorship: An 18-Year Publication Analysis.
    Megan Prunty, Stephen Rhodes, Helen Sun, Sarah P Psutka, Kirtishri Mishra, Alexander Kutikov, David Chen, Lee Ponsky, Adam Calaway, Laura Bukavina.
       BACKGROUND: Academic authorship is a critical productivity metric used for academic promotion.
    OBJECTIVE: To characterize temporal changes in female representation in academic authorship in ten primary urology journals as the complement of female urologists is increasing.
    DESIGN, SETTING, AND PARTICIPANTS: Publication records were retrieved from 2002 to 2020 for the ten urology journals with the highest impact factor. The names of all authors were gathered and gender was inferred using first names.
    OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Trends in first and last/senior authorship by gender were evaluated overall, within journals, and by geographic region.
    RESULTS: A total of 59,375 articles were analyzed, of which 94.1% had gender information for the first author and 94.2% had gender information for the last author. The percentage of overall female authors increased positively from 17.2% (95% highest density interval [HDI] 12.9-21.4%) in 2002 to 27.2% (HDI 21.7-33.6%; p < 0.01) in 2020. Overall female first authorship increased from 15.2% (95% HDI 11.0-19.5%) to 28.5% (95% HDI 21.8-35.6%; p < 0.01). There was also significant growth for female senior authors from 10.4% (95% HDI 7.6-13.5%) to 18.6% (95% HDI 13.6-23.8%; p < 0.01). Assessment of journal-specific changes revealed that Neurourology and Urodynamics (12.6%, 95% HDI 9.9-15.1%) and The Journal of Sexual Medicine (16.2%, 95% HDI 13.6-19.0%) had significantly higher growth in female authorship when compared to Journal of Endourology (7.2%, 95% HDI 5.5-8.7%) and Urologic Oncology (4.5%, 95% HDI 2.0-6.8%; p < 0.05).
    CONCLUSIONS: Although overall female authorship increased between 2002 and 2020, women remain underrepresented in urology authorship. The percentage of females in senior (last) author positions is less than the percentage of females in first author positions. Journal-specific differences can probably be attributed to gender-based differences in subspecialized fields.
    PATIENT SUMMARY: In this study, we characterized the underrepresentation of women as authors in urology journals and analyzed the change in female authorship for ten academic urology journals over the course of 18 years. Although the proportion of female authors has increased over that time, the percentage of females in senior authorship roles is less than the percentage of females in first author positions.
    Keywords:  Gender; Practice patterns; Urology; Women
    DOI:  https://doi.org/10.1016/j.euf.2021.12.001
  18. Heliyon. 2021 Dec;7(12): e08603
    How digital marketing evolved over time: A bibliometric analysis on scopus database.
    Mohammad Faruk, Mahfuzur Rahman, Shahedul Hasan.
      Nowadays, a large number of customers are spending their time on social and digital media for a variety of purposes ranging from information searching to the final purchase of products. Responding to this shift, marketers are spending a significant part of the advertising budget on digital marketing. Therefore, the purpose of this study is to review articles on digital marketing to identify top themes, determine the current status of research in digital marketing and indicate how influential works have shaped it. This research has reviewed 925 papers published between 2000 and 2019 in Scopus by applying bibliometrics analysis. These results show that on average 2.18 authors have contributed to every single paper on digital marketing and the collaboration index is 2.71. The top contributing countries in the digital marketing field are USA, India and UK. The study also identifies three dominant clusters in digital marketing research, e.g., 1) strategic planning with digital marketing 2) mobile marketing with apps development and 3) dealing with demographic profiles of customers.
    Keywords:  4th industrial revolution; Bibliometric analysis; Digital marketing; Scopus database
    DOI:  https://doi.org/10.1016/j.heliyon.2021.e08603
  19. Health Care Manag Sci. 2022 Jan 04.
    Bibliometric analysis of cancer care operations management: current status, developments, and future directions.
    Majed Hadid, Adel Elomri, Tarek El Mekkawy, Laoucine Kerbache, Abdelfatteh El Omri, Halima El Omri, Ruba Y Taha, Anas Ahmad Hamad, Mohammed Hamad J Al Thani.
      Around the world, cancer care services are facing many operational challenges. Operations management research can provide important solutions to these challenges, from screening and diagnosis to treatment. In recent years, the growth in the number of papers published on cancer care operations management (CCOM) indicates that development has been fast. Within this context, the objective of this research was to understand the evolution of CCOM through a comprehensive study and an up-to-date bibliometric analysis of the literature. To achieve this aim, the Web of Science Core Collection database was used as the source of bibliographic records. The data-mining and quantitative tools in the software Biblioshiny were used to analyze CCOM articles published from 2010 to 2021. First, a historical analysis described CCOM research, the sources, and the subfields. Second, an analysis of keywords highlighted the significant developments in this field. Third, an analysis of research themes identified three main directions for future research in CCOM, which has 11 evolutionary paths. Finally, this paper discussed the gaps in CCOM research and the areas that require further investigation and development.
    Keywords:  Bibliometric; Biblioshiny; Cancer care operations management; Cancer care services; Operations research; Thematic evolution
    DOI:  https://doi.org/10.1007/s10729-021-09585-x
  20. Proc Natl Acad Sci U S A. 2022 Jan 11. pii: e2113067119. [Epub ahead of print]119(2):
    Intersectional inequalities in science.
    Diego Kozlowski, Vincent Larivière, Cassidy R Sugimoto, Thema Monroe-White.
      The US scientific workforce is primarily composed of White men. Studies have demonstrated the systemic barriers preventing women and other minoritized populations from gaining entry to science; few, however, have taken an intersectional perspective and examined the consequences of these inequalities on scientific knowledge. We provide a large-scale bibliometric analysis of the relationship between intersectional identities, topics, and scientific impact. We find homophily between identities and topic, suggesting a relationship between diversity in the scientific workforce and expansion of the knowledge base. However, topic selection comes at a cost to minoritized individuals for whom we observe both between- and within-topic citation disadvantages. To enhance the robustness of science, research organizations should provide adequate resources to historically underfunded research areas while simultaneously providing access for minoritized individuals into high-prestige networks and topics.
    Keywords:  bibliometrics; gender; intersectionality; race; science of science
    DOI:  https://doi.org/10.1073/pnas.2113067119
  21. Rev Panam Salud Publica. 2021 ;45 e159
    Research challenges and opportunities in the Caribbean area: first bibliometric study in the French West Indies, from 1989 to 2018.
    Cédric Contaret, Raymond Cesaire, Jacqueline Deloumeaux, Rémi Neviere, Dabor Resiere, André Cabie, Emmanuelle Sylvestre, Clarisse Joachim, Moustapha Drame.
       Objective: To analyze, describe, and quantify the collaborations and scientific output of the two university teaching hospitals of Martinique and Guadeloupe, at the regional, national, and international level.
    Methods: A bibliometrics analysis was performed from the international databases Web of Science and PubMed, for the period from 1989 to 2018, inclusive (30 years). Three types of bibliometric indicators were used, namely quantitative indicators, performance indicators, and organization-specific indicators. Affiliations of the first and last authors were identified from PubMed.
    Results: Between 1989 and 2018, a total of 1 522 indexed articles were published with at least one author affiliated to either the University Hospital of Martinique (n = 827) or the University Hospital of Guadeloupe (n = 685). The majority of articles were in category Q1 (35.8% for Martinique and 35.2% for Guadeloupe). In Martinique, over the last 30 years, the three main research areas have been clinical neurology, ophthalmology, and surgery, together representing 28.7% of all research areas, with the highest number of articles published in the field of clinical neurology (n = 81). In the University Hospital of Guadeloupe, the area of hematology was largely represented, with 79 articles published. For both hospitals, the first and last authors of the articles published were mainly from mainland France.
    Conclusions: This quantitative analysis shows the development of medical and scientific research in Martinique and Guadeloupe over the last three decades, as well as the extent of their collaborative partnerships at the national and international levels.
    Keywords:  Caribbean region; Collaboration indicator; Guadeloupe; Martinique; bibliometrics
    DOI:  https://doi.org/10.26633/RPSP.2021.159
  22. Med Sci Monit. 2022 Jan 03. 28 e933448
    Relationships Between Obstructive Sleep Apnea and Cardiovascular Disease: A Bibliometric Analysis (2010-2021).
    Yumeng Wang, Xintian Shou, Yang Wu, Zongjing Fan, Jie Cui, Rui Zhuang, Ruixiang Luo.
      BACKGROUND Obstructive sleep apnea (OSA) is a common disease that can lead to intermittent hypoxia, increased sympathetic overdrive, and excessive oxidative stress, and eventually lead to cardiovascular/cerebrovascular diseases and metabolic disorders. The prevalence of OSA is reported to be higher in people with certain cardiovascular diseases (CVD). Therefore, the relationship between OSA and CVD has been gradually favored by researchers. MATERIAL AND METHODS Data were downloaded from the Web of Science Core Collection database. Citespace was used to remove duplicated data and construct knowledge visual maps. RESULTS A total of 7047 publications were obtained. The USA was the largest contributor as well as an important player in the cooperation network between nations. The leading institution was the Mayo Clinic. Our study ultimately identified the top 5 hotspots and 4 research frontiers in this field. Top 5 hotspots were: the specific types of obstructive sleep apnea-related cardiovascular and metabolic co-morbidities, the curative effects of CPAP on these co-morbidities, the specific mechanisms of co-morbidities, the importance of polysomnography on OSA and its co-morbidities with CVD, and the prevalence of OSA and its co-morbidities with CVD in particular populations. The top 4 frontiers were: the relationship between OSA and resistant hypertension, the molecular mechanisms of OSA and its co-morbidities with CVD, specific medications and treatment guidelines for the co-morbidities, and the mainstream research methods in this field. CONCLUSIONS This study provides insight and valuable information for researchers and helps to identify new perspectives concerning potential collaborators and cooperative institutions, hot topics, and research frontiers in this field.
    DOI:  https://doi.org/10.12659/MSM.933448
  23. Zhongguo Zhong Yao Za Zhi. 2021 Dec;46(24): 6549-6557
    [Hotspots and trends of Ophiopogonis Radix based on CiteSpace knowledge map].
    Zi-Ling Zeng, Lin Tong, Si-Hong Liu, Lei Zhang, Hong-Jie Gao, Guang-Kun Chen, Hua-Min Zhang.
      Ophiopogonis Radix is an important Yin-nourishing drug in traditional Chinese medicine(TCM), with the effects of nourishing Yin, promoting fluid production, clearing away heart-fire, and relieving restlessness. It is widely used in clinical practice due to its multiple chemical components and pharmacological effects. The technique &quot;mapping knowledge domains&quot; is an effective tool to quantitatively and objectively visualize the development frontiers and trends of certain disciplines. In this study, TCM research papers related to Ophiopogonis Radix were retrieved from Web of Science(WoS) and CNKI, and the research institutions, journals, and keywords involved were visualized and analyzed using the scientometric software CiteSpace. The co-occurrence network of related research on Ophiopogonis Radix was constructed, and the Ophiopogonis Radix-disease-target network was plotted using Cytoscape 3.8.2. The hot topics in Chinese and English papers were analyzed and the shortcomings in the research on Ophiopogonis Radix were summed up. Furthermore, the development trends were discussed. A total of 1 403 Chinese papers and 292 English papers were included in this study. The analysis of research institutions showed that Beijing University of Chinese Medicine and China Pharmaceutical University were the two research institutions with the largest numbers of papers published. The analysis of journals showed that Hebei Journal of Traditional Chinese Medicine and Journal of Asian Natural Products Research were the two journals with the highest numbers of papers concerning Ophiopogonis Radix. The keyword analysis showed that the research contents of Chinese papers focused on the analysis of medication regularity and clinical observation trials, while the English papers focused on component analysis and pharmacological investigation. Data mining and apoptosis-based pharmacological mechanism might be the research trends in the future.
    Keywords:  CiteSpace; Cytoscape 3.8.2; Ophiopogonis Radix; content analysis method; scientometrics
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20210802.501
  24. Arthrosc Sports Med Rehabil. 2021 Dec;3(6): e1629-e1636
    Orthopaedic Foot and Ankle Surgery Fellowship Directors Are Typically White Men in Their Early 50s With Strong Achievements in Research.
    Muhammad Ali Elahi, M Lane Moore, Matthew K Doan, Jordan R Pollock, Jeffrey D Hassebrock, Justin L Makovicka, Joseph C Brinkman, Karan A Patel.
       Purpose: To determine the objective characteristics of orthopaedic foot and ankle fellowship directors (FDs) by concentrating on the demographic characteristics, academic background, institutional history, research experience, and professional affiliations of these leaders.
    Methods: Data for each FD were collected by searching institutional biographies, personal websites, or publicly available curricula vitae. Data collection included the following variables: age, sex, race/ethnicity, previous training institutions, residency and fellowship graduation years, advanced degrees, military affiliation, institutional loyalty, year hired, FD career timeline, total number of publications, total number of citations, and h-index.
    Results: Of the 47 FDs, 44 (93.6%) were men and 3 (6.4%) were women. The mean age was 50.8 ± 9.4 years. Most orthopaedic foot and ankle FDs were white (n = 42, 89.4%), followed by Asian (n = 4, 8.5%) and black or African American (n = 1, 2.1%). The mean Scopus h-index, total number of publications, and total number of citations for all foot and ankle FDs were 13.3 ± 9.5, 47.5 ± 45.8, and 898.1 ± 1,040.3, respectively. Among all foot and ankle FDs, the mean tenure in the FD position was 5.8 ± 4.6 years.
    Conclusions: Orthopaedic foot and ankle FDs are primarily white men in their 50s, with minimal female and minority representations. These FDs are distinguished by their high level of research productivity. Additionally, orthopaedic foot and ankle training backgrounds seem to play an important role, given that most of the appointed FDs trained in only a few select programs.
    Clinical Relevance: This study outlines some of the most important characteristics among foot and ankle FDs and identifies important disparities within this population of leaders that may have detrimental effects on the field.
    DOI:  https://doi.org/10.1016/j.asmr.2021.07.018
  25. Vet Surg. 2022 Jan 05.
    Publication rate and evidence-based evaluation of abstracts presented at the veterinary endoscopy society annual meeting (2004-2019).
    Karen E Moy-Trigilio, Nicole J Buote, Stephen Parry.
       OBJECTIVE: To determine the rate of full-length publication for the 2004-2019 Veterinary Endoscopy Society (VES) annual meeting abstracts and to identify abstract and author characteristics as predictors of publication.
    STUDY DESIGN: Observational bibliographical study.
    SAMPLE POPULATION: Three hundred and eighty-nine abstracts.
    METHODS: Abstracts from 2004-2019 Veterinary Endoscopy Society (VES) proceedings and matching full-length publications retrieved from bibliographic databases were systematically reviewed. Variables assessed included species, specimen type (cadaver, live animal, etc.), subdiscipline (orthopedics, internal medicine, etc.), institution, country of origin, study design, level of evidence (LoE), time to publication, number of authors, their credentials, and gender. Logistic regression, Fisher's exact tests and t-tests were used to assess the bivariate relationship between publication and characteristics of the authors and publications.
    RESULTS: The overall publication rate for presented abstracts published as full-length articles in peer-reviewed journals was 26%. Median time from abstract presentation to full-length article publication was 430 days. Factors associated with full-length article publication were identified: affiliated institution (P = .01), species studied (P = .04), subdiscipline focus (P = .01), level of evidence (P = .01), number of authors (P = .01), and first author's gender (P = .03).
    CONCLUSION: Veterinary Endoscopy Society abstracts were commonly categorized into a lower LoE. Abstracts from academic institutions regarding canine patients and soft tissue surgery topics were more likely to be published. Abstracts citing female first authors or with more than 1 author had higher odds of publication.
    CLINICAL SIGNIFICANCE: Data reported provide authors with predictors for publication and identify topics for research opportunities. Veterinary specialty societies may utilize this information when evaluating abstracts.
    DOI:  https://doi.org/10.1111/vsu.13761
  26. Clin Trials. 2022 Jan 06. 17407745211063423
    Influential methods reports for group-randomized trials and related designs.
    David M Murray.
       BACKGROUND: This article identifies the most influential methods reports for group-randomized trials and related designs published through 2020. Many interventions are delivered to participants in real or virtual groups or in groups defined by a shared interventionist so that there is an expectation for positive correlation among observations taken on participants in the same group. These interventions are typically evaluated using a group- or cluster-randomized trial, an individually randomized group treatment trial, or a stepped wedge group- or cluster-randomized trial. These trials face methodological issues beyond those encountered in the more familiar individually randomized controlled trial.
    METHODS: PubMed was searched to identify candidate methods reports; that search was supplemented by reports known to the author. Candidate reports were reviewed by the author to include only those focused on the designs of interest. Citation counts and the relative citation ratio, a new bibliometric tool developed at the National Institutes of Health, were used to identify influential reports. The relative citation ratio measures influence at the article level by comparing the citation rate of the reference article to the citation rates of the articles cited by other articles that also cite the reference article.
    RESULTS: In total, 1043 reports were identified that were published through 2020. However, 55 were deemed to be the most influential based on their relative citation ratio or their citation count using criteria specific to each of the three designs, with 32 group-randomized trial reports, 7 individually randomized group treatment trial reports, and 16 stepped wedge group-randomized trial reports. Many of the influential reports were early publications that drew attention to the issues that distinguish these designs from the more familiar individually randomized controlled trial. Others were textbooks that covered a wide range of issues for these designs. Others were "first reports" on analytic methods appropriate for a specific type of data (e.g. binary data, ordinal data), for features commonly encountered in these studies (e.g. unequal cluster size, attrition), or for important variations in study design (e.g. repeated measures, cohort versus cross-section). Many presented methods for sample size calculations. Others described how these designs could be applied to a new area (e.g. dissemination and implementation research). Among the reports with the highest relative citation ratios were the CONSORT statements for each design.
    CONCLUSIONS: Collectively, the influential reports address topics of great interest to investigators who might consider using one of these designs and need guidance on selecting the most appropriate design for their research question and on the best methods for design, analysis, and sample size.
    Keywords:  Group-randomized trial; cluster-randomized trial; individually randomized group treatment trial; stepped wedge cluster-randomized trial; stepped wedge group-randomized trial
    DOI:  https://doi.org/10.1177/17407745211063423
  27. PLoS One. 2022 ;17(1): e0261503
    Global cervical cancer research: A scientometric density equalizing mapping and socioeconomic analysis.
    Dörthe Brüggmann, Kathrin Quinkert-Schmolke, Jenny M Jaque, David Quarcoo, Michael K Bohlmann, Doris Klingelhöfer, David A Groneberg.
      Cervical cancer has caused substantial morbidity and mortality for millions of women over the past decades. While enormous progress has been made in diagnosis, prevention and therapy, the disease is still fatal for many women-especially in low-income countries. Since no detailed studies are available on the worldwide research landscape, we here investigated the global scientific output related to this cancer type by an established protocol. The "New Quality and Quantity Indices in Science" platform assessed all relevant cervical cancer research published in the Web of Science since 1900. A detailed analysis was conducted including country-specific research productivity, indicators for scientific quality, and relation of research activity to socioeconomic and epidemiologic figures. Visualization of data was generated by the use of density equalizing map projections. Our approach identified 22,185 articles specifically related to cervical cancer. From a global viewpoint, the United States of America was the dominating country in absolute numbers, being followed by China and Japan. By contrast, the European countries Sweden, Austria, and Norway were positioned first when the research activity was related to the population number. When the scientific productivity was related to annual cervical cancer cases, Scandinavian countries (Finland #1, Sweden #4, Norway #5, Denmark #7), the Alpine countries Austria (#2) and Switzerland (#6), and the Netherlands (#3) were leading the field. Density equalizing mapping visualized that large parts of Africa and South America were almost invisible regarding the global participation in cervical cancer research. Our data documented that worldwide cervical cancer research activity is continuously increasing but is imbalanced from a global viewpoint. Also, the study indicated that global and public health aspects should be strengthened in cervical carcinoma research in order to empower more countries to take part in international research activities.
    DOI:  https://doi.org/10.1371/journal.pone.0261503
  28. PLoS Biol. 2022 Jan 06. 20(1): e3001520
    The characteristics of early-stage research into human genes are substantially different from subsequent research.
    Thomas Stoeger, Luís A Nunes Amaral.
      Throughout the last 2 decades, several scholars observed that present day research into human genes rarely turns toward genes that had not already been extensively investigated in the past. Guided by hypotheses derived from studies of science and innovation, we present here a literature-wide data-driven meta-analysis to identify the specific scientific and organizational contexts that coincided with early-stage research into human genes throughout the past half century. We demonstrate that early-stage research into human genes differs in team size, citation impact, funding mechanisms, and publication outlet, but that generalized insights derived from studies of science and innovation only partially apply to early-stage research into human genes. Further, we demonstrate that, presently, genome biology accounts for most of the initial early-stage research, while subsequent early-stage research can engage other life sciences fields. We therefore anticipate that the specificity of our findings will enable scientists and policymakers to better promote early-stage research into human genes and increase overall innovation within the life sciences.
    DOI:  https://doi.org/10.1371/journal.pbio.3001520
  29. Data Brief. 2022 Feb;40 107695
    Key performance indicators of Russian universities for 2015-2018: Dataset and Benchmarking Data.
    Anna I Guseva, Viacheslav M Kalashnik, Vladimir I Kaminskii, Sergey V Kireev.
      This article presents a performance dataset of 93 Russian universities, collected from 2015 to 2018 and evaluated according to 24 indicators. These data were gathered from materials, published in the process of monitoring the effectiveness of higher education institutions by the Ministry of Science and Higher Education of the Russian Federation, Web of Science (citation-based research analytics tool InCites) and Scopus (citation-based research analytics tool SciVal) databases, and information from international ranking agencies QS, THE, ARWU. The dataset comprises the assessments of university performances according to the most important indicators used in socio-economic studies of comparative analysis of higher education system development levels in different countries: educational, scientific and research, international, financial and economic performance and international public recognition (university positions in leading international rankings). Evaluated universities are grouped pursuant to their missions: Federal Universities (FU), National Research Universities (NRU), Flagship Universities (FlU) and university-participants of the Russian Academic Excellence Project (Project 5-100). The indicators for the comparative analysis are aggregated by the type of activities and analyzed based on the calculation of median values and Displaced Ideal Method. The dataset can be helpful to researchers, university administration, specialists of higher education system, etc. Data processing can be executed using data mining methods, machine learning, and pattern analysis for the development of intellectual structures, applicable for university performance assessment in different educational systems. Presented data allows us to assert that the implementation of targeted support for leading Russian universities has a positive impact on the development of Russian higher education increasing its role on the international academic arena. Leading national research university-participants of the Project 5-100 had the greatest influence on increasing the competitiveness of Russian education in the world.
    Keywords:  Data collection and processing algorithms; Displaced Ideal Method; National Research Universities; Russian Academic Excellence Project; World University Rankings
    DOI:  https://doi.org/10.1016/j.dib.2021.107695
  30. Angiology. 2022 Jan 07. 33197211062280
    Applications of Artificial Intelligence in Non-cardiac Vascular Diseases: A Bibliographic Analysis.
    Fabien Lareyre, Cong Duy Lê, Ali Ballaith, Cédric Adam, Marion Carrier, Samantha Amrani, Caroline Caradu, Juliette Raffort.
      Research output related to artificial intelligence (AI) in vascular diseases has been poorly investigated. The aim of this study was to evaluate scientific publications on AI in non-cardiac vascular diseases. A systematic literature search was conducted using the PubMed database and a combination of keywords and focused on three main vascular diseases (carotid, aortic and peripheral artery diseases). Original articles written in English and published between January 1995 and December 2020 were included. Data extracted included the date of publication, the journal, the identity, number, affiliated country of authors, the topics of research, and the fields of AI. Among 171 articles included, the three most productive countries were USA, China, and United Kingdom. The fields developed within AI included: machine learning (n = 90; 45.0%), vision (n = 45; 22.5%), robotics (n = 42; 21.0%), expert system (n = 15; 7.5%), and natural language processing (n = 8; 4.0%). The applications were mainly new tools for: the treatment (n = 52; 29.1%), prognosis (n = 45; 25.1%), the diagnosis and classification of vascular diseases (n = 38; 21.2%), and imaging segmentation (n = 38; 21.2%). By identifying the main techniques and applications, this study also pointed to the current limitations and may help to better foresee future applications for clinical practice.
    Keywords:  Artificial intelligence; bibliographic analysis; bibliometry; deep learning; machine learning; vascular diseases
    DOI:  https://doi.org/10.1177/00033197211062280
  31. Front Psychol. 2021 ;12 773916
    Diversity in Psychological Research Activities: Quantitative Approach With Topic Modeling.
    Sachio Otsuka, Yoshiyuki Ueda, Jun Saiki.
      Recent cultural studies have discussed universality and diversity in human behavior using numerous samples investigated worldwide. We aimed to quantitatively extend this discussion to various research activities in psychology in terms of geographic regions and time trends. Most psychology departments have specialists in various fields of psychology. Further, research institutions in all regions typically aim to provide systematic and balanced research education. Nevertheless, most researchers recognize universal features and patterns of diversity in research activities in psychology in terms of regional differences and time trends. However, these arguments remain intuitive and vague, and no studies have conducted quantitative analyses. To this end, we conducted topic modeling for the abstracts of psychological articles with the regions of author affiliations and publication periods as covariates. The results showed that the topic proportions related to basic research were high in North-Central America, whereas those related to clinical research were high in Europe. Interestingly, the regional differences shown by topic modeling were not observed in the frequency analysis of keywords, indicating that topic modeling revealed implicit characteristics. Moreover, we observed an increasing trend of neuroscience topics across publication periods. However, this trend was not valid for the psychology journal Psychological Science. Taken together, our results suggest diversity of geographic regions and periods in research activities in psychology. More importantly, our findings indicate that universality holds neither for human behavior nor research activities on human mental processes.
    Keywords:  diversity; publication period; regional difference; text mining; topic modeling
    DOI:  https://doi.org/10.3389/fpsyg.2021.773916
  32. CJC Open. 2021 Dec;3(12 Suppl): S12-S18
    National Trends of Gender Disparity in Canadian Cardiovascular Society Guideline Authors, 2001-2020.
    Devesh Rai, Syed Hamza Waheed, Miranda Guerriero, Muhammad Waqas Tahir, Ritambhara Pandey, Harsh Patel, Samarthkumar Thakkar, Sharon L Mulvagh, Alexandra Bastiany, Shelley Zieroth, Colleen M Norris, Harriette G C Van Spall, Erin D Michos, Martha Gulati.
       Background: The level of representation of women in cardiology remains low compared to that of men, particularly in leadership positions. We evaluated gender disparity in the authorship of Canadian Cardiovascular Society (CCS) guidelines.
    Methods: All CCS guidelines from 2001-2020 were identified. Gender was assessed based on pronoun use in the biographies and social media of the authors. Only primary panel authors were included in our analysis. Stratified analyses were performed based on subspecialties.
    Results: A total of 76 guidelines were identified, with 1172 authors (26% women, 74% men, P < 0.0001), with no significant change in percentage of women authors over 2 decades, (37.1% in 2001, 36.3% in 2020, P = 0.34). Inclusion of women as authors occurred less frequently than inclusion of men in general cardiology guidelines (20.1% vs 79.9%, P < 0.0001) and all subspecialties-heart failure (36.4% vs 63.6%, P < 0.0001), interventional cardiology (12.6% vs 87.4%, P < 0.0001), electrophysiology (20.2% vs 79.8%, P < 0.0001), and pediatric cardiology (41.7% vs 58.3%, P = 0.02). It was less likely for women to be a chair or cochair of a guideline writing committee, compared with men (20.1% vs 79.8%, P < 0.0001). There were 609 unique authors (25.6% women, 74.4% men, P < 0.0001), 542 unique medical doctorate (MD) authors (20.7% women, 79.3% men, P < 0.0001), and 67 unique non-MD authors (65.7% women, 34.3% men, P = 0.0003).
    Conclusions: There is a persistent shortfall in the inclusion of women authors for CCS guidelines, which has not changed over time. Further efforts are required to promote women's inclusion in leadership roles, which may lead to authorship of the guidelines.
    DOI:  https://doi.org/10.1016/j.cjco.2021.04.003
  33. Environ Sci Pollut Res Int. 2022 Jan 08.
    Progress in the interaction of dissolved organic matter and microbes (1991-2020): a bibliometric review.
    Xuan Yang, Yun Zhang, Qi Liu, Jishu Guo, Qichao Zhou.
      Dissolved organic matter (DOM) and microbes are key in the planetary carbon cycle, and research on them can lead to a better understanding of the global carbon cycle and an improved ability to cope with environmental challenges. Several papers have reviewed one or several aspects of the interaction of DOM and microbes, but no overall review has been performed. Here, we bibliometrically analyzed all publications from the Web of Science on DOM and microbes (1991-2020). The results showed that studies on DOM and microbes grew exponentially during this period; the USA contributed the most to the total publications, and China has had the fastest increasing rate since 2010. Moreover, we used the Latent Dirichlet Allocation model to identify topics and determine their (cold or hot) trends by analyzing the abstracts of 9851 publications related to DOM and microbes. A total of 96 topics were extracted, and these topics that are related to the source, composition, and removal path of DOM and the temporal-spatial patterns of DOM and microbes consistently rose from 1991 to 2020. Most studies have used accurate and rapid methods combined with microbiological genetic approaches to study the interaction of DOM and microbes in terrestrial and aquatic ecosystems. The results also showed that the impacts of climate change and land use on the interaction of DOM and microbes, and topics related to human health have received considerable attention. In the future, the interaction mechanism of DOM and microbes and its response to environmental change should be further elucidated.
    Keywords:  Bibliometrics; Dissolved organic matter; Environmental change; Human health; Interaction; Microbes; Study areas and techniques
    DOI:  https://doi.org/10.1007/s11356-022-18540-4
  34. JAMA Netw Open. 2022 Jan 04. 5(1): e2142513
    Gender Disparities Among Highly Cited Researchers in Biomedicine, 2014-2020.
    Amrollah Shamsi, Brady Lund, Mohammad Javad Mansourzadeh.
      
    DOI:  https://doi.org/10.1001/jamanetworkopen.2021.42513
  35. Prev Med Rep. 2021 Dec;24 101604
    Firearm-related research articles in health sciences by funding status and type: A scoping review.
    Sixtine Gurrey, Hasanah McCauley, Melanie Benson, Pavithra Prabhu, Mary D Fan, Frederick P Rivara, David Hemenway, Matthew Miller, Deborah Azrael, Ali Rowhani-Rahbar.
      Federal funding for firearm-related research in the health sciences has incurred Congressional restrictions and executive actions. Little is known about the funding landscape for published scholarship in this field. This study's aim was to characterize the number and sources of funding, including federal and non-federal sources, for firearm-related research articles published in health sciences journals. We performed a scoping review of original, empirical, peer-reviewed articles related to firearms published in health science journals and indexed in PubMed between January 2000 and December 2019, using the PRISMA extension for Scoping Review checklist. Four reviewers independently screened each article twice for inclusion. Included articles were reviewed again to identify funding sources. Articles were characterized as having explicitly declared funding, explicitly declared no funding, or no explicit funding declaration. Among articles with funding, we examined proportions by funding source. 812 articles met the inclusion criteria. 119 (14.7%) of the articles declared not having received any funding, and 240 (29.6%) had no funding declaration. 453 (55.8%) of the articles declared at least one source of funding. Of those, 221 (48.8%) reported at least one federal grant, and 232 (51.2%) reported at least one philanthropic grant. The number of published articles increased by 328.6% between 2000 and 2019. While the volume increased during the study period, the proportion of articles with funding was lower in 2019 (55.6%) than it was in 2000 (87.5%; proportion difference: 31.9%; 95% CI: 16.7%-47.2%). This study highlights the continued funding limitations in this field despite a growing volume of research.
    Keywords:  CDC, Centers for Disease Control and Prevention; Firearms; Funding; Health sciences; Injury; NIH, National Institutes of Health; Violence
    DOI:  https://doi.org/10.1016/j.pmedr.2021.101604
  36. Med Care. 2022 Jan 05.
    Mapping 2 Decades of Research in Health Services Research, Health Policy, and Health Economics Journals.
    Ferhat D Zengul, Nurettin Oner, Bunyamin Ozaydin, Allyson G Hall, Eta S Berner, James J Cimino, Christy H Lemak.
       OBJECTIVE: To identify major research topics and exhibit trends in these topics in 15 health services research, health policy, and health economics journals over 2 decades.
    DATA SOURCES: The study sample of 35,159 abstracts (1999-2020) were collected from PubMed for 15 journals.
    STUDY DESIGN: The study used a 3-phase approach for text analyses: (1) developing the corpus of 40,618 references from PubMed (excluding 5459 of those without abstract or author information); (2) preprocessing and generating the term list using natural language processing to eliminate irrelevant textual data and identify important terms and phrases; (3) analyzing the preprocessed text data using latent semantic analysis, topic analyses, and multiple correspondence analysis.
    PRINCIPAL FINDINGS: Application of analyses generated 16 major research topics: (1) implementation/intervention science, (2) HIV and women's health, (3) outcomes research and quality, (4)veterans/military studies, (5) provider/primary-care interventions, (6) geriatrics and formal/informal care, (7) policies and health outcomes, (8) medication treatment/therapy, (9) patient interventions, (10) health insurance legislation and policies, (11) public health policies, (12) literature reviews, (13) cost-effectiveness and economic evaluation, (14) cancer care, (15) workforce issues, (16) socioeconomic status and disparities. The 2-dimensional map revealed that some journals have stronger associations with specific topics. Findings were not consistent with previous studies based on user perceptions.
    CONCLUSION: Findings of this study can be used by the stakeholders of health services research, policy, and economics to develop future research agendas, target journal submissions, and generate interdisciplinary solutions by examining overlapping journals for particular topics.
    DOI:  https://doi.org/10.1097/MLR.0000000000001685
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