bims-evares Biomed News
on Evaluation of research
Issue of 2021–12–26
forty papers selected by
Thomas Krichel, Open Library Society



  1. J Evid Based Dent Pract. 2021 Dec;pii: S1532-3382(21)00096-8. [Epub ahead of print]21(4): 101621
       BACKGROUND: Randomized controlled trials (RCTs) in dentistry provide essential evidence for dentists to practice evidence-based dentistry. This study aimed to analyze the scientific impacts of the RCTs conducted among children and adolescents published in dental journals and summarize the main contents of these studies.
    METHODS: An electronic literature search was conducted in the database Web of Science (WoS) Core Collection by two independent reviewers in June 2020, without an initial time limit. Articles reporting on RCTs conducted among children and adolescents in dental fields were identified. The most cited articles (the top 100 articles based on total citation counts and citation density) were selected. The bibliometric data were exported from the database WoS for further analysis. The citation counts were cross-checked in Google Scholar. In addition, the main content of the included RCTs was extracted and summarized.
    RESULTS: A total of 132 papers published in 28 journals reporting on RCTs in dentistry on children and adolescents were included in this study. The mean total citation count (within WoS) of the included RCTs was 60.0, ranging from 17 to 300, and the mean citation density value was 4.6, ranging from 1.3 to 15.0. The majority of the articles were in the thematic field of cariology (n = 79, 59.8%). Other thematic fields, orthodontology (20.5%), endodontology (5.3%), behavior science and quality of life (5.3%), oral and maxillofacial surgery (3.8%), oral hygiene (3.8%) and periodontology (1.5%) were involved as well. Around one-fifth of the articles (n = 23) were produced by the United States, and the included articles were most cited by the publications (n = 1937) from the United States as well.
    CONCLUSIONS: A wide range of dental topics were covered in the included RCTs conducted among children and adolescents. These top-cited RCTs mainly focus on the thematic field of cariology. The United States is an influential country with a large number of publication outputs and citations.
    Keywords:  Adolescent; Bibliometric analysis; Children; Dentistry; Randomized controlled trial
    DOI:  https://doi.org/10.1016/j.jebdp.2021.101621
  2. Chin Neurosurg J. 2021 Dec 19. 7(1): 50
       BACKGROUND: Cerebrovascular disease has become the leading cause of death in China. The purpose of this article is to analyze China's contribution to the interventional treatment of cerebrovascular diseases.
    METHODS: Bibliometric analysis was used for evaluating the quantity, quality, research hotspots, and cooperation network of publications regarding interventional treatment of cerebrovascular diseases from China. These articles were searched from the database of Web of Science Core Collection. The authors, publication years, citation times, regions, and source journals of retrieved articles were recorded. Network analysis and visualization were performed on Citespace5.6.
    RESULTS: From 1991 to 2019, a total of 5052 articles regarding cerebrovascular intervention were contributed by Chinese researchers. The number of publications from China grew fastest annually in the latest 5 years among countries. These publications were cited 61,216 times, with 12.12 average citations per item. The h-index was 82. Affiliated hospitals of Capital Medical University contributed most articles. Cerebral ischemia and intracranial aneurysm were the most popular keywords over the three decades. The timeline view of keywords indicated that cerebral ischemia always was a hot spot. Stent techniques were the main treatment tools and still had a strong developing trend. Neural regeneration and neuroprotection were the hot topics of basic researches related to cerebrovascular intervention.
    CONCLUSIONS: The number of researches grows rapidly in China over the decades, but the quality still needs further improvement. The increasing contributions of Chinese researchers to the global knowledge system of cerebrovascular intervention are promising.
    Keywords:  Bibliometrics; Cerebrovascular disorders; Endovascular procedures; Interventional radiology; Stroke
    DOI:  https://doi.org/10.1186/s41016-021-00264-y
  3. Front Pharmacol. 2021 ;12 772386
      Background: Podocyte injury has a direct causal relationship with proteinuria and glomerulosclerosis and, on a chronic level, can lead to irreversible disease progression. Podocyte injury plays a critically decisive role in the development of proteinuric kidney disease. In recent years, the research on podocyte injury has developed rapidly all over the world. However, no report has summarized the field of podocyte injury as a whole to date. Using bibliometric analysis, this study aimed to evaluate the current state of worldwide podocyte injury research in the last 30 years and identify important achievements, primary research fields, and emerging trends. Methods: Publications related to podocyte injury were retrieved from Web of Science Core Collection. HistCite, VOSviewer, CiteSpace, and the Bibliometrix Package were used for bibliometric analysis and visualization, including the analysis of the overall distribution of annual outputs, leading countries, active institutions and authors, core journals, co-cited references, and keywords. Total global citation score and total local citation score were used to assess the quality and impact of publications. Results: A total of 2,669 publications related to podocyte injury were identified. Publications related to podocyte injury tended to increase continuously. A total of 10,328 authors from 2,171 institutions in 69 countries published studies related to podocyte injury. China (39.46%) was the most prolific country, and the number of citations of studies in the United States (cited 36,896 times) ranked first. Moin A Saleem, John Cijiang He, and Zhihong Liu were the top three contributing authors, and Journal of the American Society of Nephrology and Kidney International were the most popular journals in the field. "Diabetic nephropathy" is the primary focus area of podocyte injury research, and "autophagy," "microRNA," and "inflammation" were the top keywords of emerging research hotspots, and traditional Chinese medicine monomer may be a neglected research gap. Conclusion: Our research found that global publications on podocyte injury have increased dramatically. Diabetic nephropathy is the main research field of podocyte injury, whereas autophagy, microRNA, and inflammation are the top topics getting current attention from scholars and which may become the next focus in podocyte injury research.
    Keywords:  VOSviewer; bibliometrics analysis; bibliometrix; citespace; histcite; podocyte injury; visualized
    DOI:  https://doi.org/10.3389/fphar.2021.772386
  4. Front Oncol. 2021 ;11 795568
       Objective: This study aims to analyze the 100 most cited papers and research trends on stereotactic body radiotherapy (SBRT).
    Methods: We used Web of Science to identify the 100 most frequently cited papers on SBRT on September 29, 2021 and extracted the following data: publication year, source title, country/region, organization, total citations, and average number of citations per year. The research type and research domain were classified independently by the authors. Then we carried out a bibliometric analysis to determine the trends in research on SBRT.
    Results: These 100 papers were cited a total of 26,540 times, and the median number of citations was 190 (range, 138-1688). "Stereotactic body radiation therapy for inoperable early stage lung cancer" by Timmerman et al. had the highest number of total citations (1688 times). International Journal of Radiation Oncology, Biology, Physics published the largest number of papers (37 papers), followed by Journal of Clinical Oncology (13 papers). The USA contributed the most papers (67 papers), followed by Canada (18 papers). Primary lung cancer (33 papers, 10,683 citations) and oligometastases (30 papers, 7,147 citations) were the most cited research areas.
    Conclusions: To the best of our knowledge, this is the first bibliometric analysis of the most frequently cited papers on SBRT. Our results provide insight into the historical development of SBRT and important advances in its application to cancer treatment. Early-stage non-small-cell lung cancer and oligometastases were the most cited research areas in the top 100 publications on SBRT, and SBRT combined with immunotherapy was a hot topic in the past few years. This study is helpful for researchers to identify the most influential papers and current research hotspots on SBRT.
    Keywords:  bibliometric analysis; immunotherapy; lung cancer; oligometastases; stereotactic ablative radiotherapy (SABR); stereotactic body radiotherapy (SBRT)
    DOI:  https://doi.org/10.3389/fonc.2021.795568
  5. Front Psychiatry. 2021 ;12 776883
      Children with developmental coordination disorder (DCD) have been commonly observed and drawn an increasing amount of attention over the past decades. The aim of the present study is to evaluate the origin, current hotspots, and research trends on children with DCD using a bibliometric tool. After searching with "children" and "developmental coordination disorder" as the "topic" and "title" words, respectively, 635 original articles with 12,559 references were obtained from the electronic databases, Web of Science Core Collection (WoSCC). CiteSpace V.5.7.R2 was used to perform the analysis. The number of publications in this field was increasing over the past two decades. John Cairney from the Department of Family Medicine, McMaster University, Canada, was found to be the most productive researcher. Meanwhile, McMaster University and Canada were the most productive research institution and country, respectively. Reference and journal co-citation analyses revealed the top landmark articles and clusters in this field. Clumsiness was the most strength burst keyword. Moreover, task, meta-analysis, difficulty, adult, and impact will be the active research hotspots in future. These findings provide the trends and frontiers in the field of children with DCD, and valuable information for clinicians and scientists to identify new perspectives with potential collaborators and cooperative countries.
    Keywords:  burst detection; children; data visualization; developmental coordination disorder; web of science
    DOI:  https://doi.org/10.3389/fpsyt.2021.776883
  6. Int J Gen Med. 2021 ;14 9707-9718
       Background: Hundreds of studies have reported the application of iodine-131 (I-131) in thyroid carcinoma (THCA) in past years. However, the status of research in the field and other related topics have not been investigated. This study aimed to identify the cooperation of authors, countries, and institutions, as well as explore the hot topics and prospects regarding I-131 therapy in THCA based on previous studies.
    Methods: Publications from 2010 to 2020 were retrieved from Web of Science Core Collection according to research strategy. Bibliometric analyses were performed using VOSviewer 1.6.15 and CiteSpace 5.7.3 to evaluate and visualize the cooperation network, hot topic, and research frontier.
    Results: The number of publications showed a trend of fluctuation between 2010 and 2020. We identified 1387 publications related to I-131 therapy in THCA, which were published by 1628 institutions from 82 countries. The largest proportion of publications were emanated from the USA, and the majority of papers were published by Thyroid. Shanghai Jiao Tong University of China contributed the most papers. Although many authors participated in the research of this field, high-yield authors were few. Co-occurrence analysis classified keywords into five clusters, including assessment, efficacy measurement, monitoring, hormone regulation, and guidelines of I-131 therapy. The terms "bone marrow dosimetry and time" were among the latest hotspots. The research frontier topic in I-131 therapy focused on the "P53 and anti-Müllerian hormone".
    Conclusion: The attention to I-131 therapy in THCA should be increased considerably. It was necessary to construct active co-operations between authors, countries, and institutions to promote the development of this field. Recent researches referred to the timing and dose assessment of I-131 therapy in THCA. Future studies likely focused on targeted therapy and adverse effects evaluation were worthy of research as well.
    Keywords:  I-131; bibliometric analysis; hot spots; research trend; thyroid carcinoma
    DOI:  https://doi.org/10.2147/IJGM.S339946
  7. Heliyon. 2021 Dec;7(12): e08551
      This paper identifies the main areas and the development of the field of internet financial reporting publications and to suggest future research directions. Internet use for corporate financial reporting represents a voluntary approach to consolidate printed sustainability reports which have increasingly been published by large companies in recent years. Using a bibliometric analysis, this paper examined a sample of 246 studies from Web of Science, Scopus, Emerald, Springer, Proquest, Ebsco, and Science Direct databases and only accepted articles and review paper were published in open access to identify research activity on internet financial reporting between 1998 until 2020. This review provides the most influential articles and authors based on their citations and publications as well as their importance within the network through network visualization, overlay visualization, and density visualization. The co-authorship analysis shows 208 authors who have connected each other, the co-organization analysis resulted 76 organizations which write article about internet financial reporting and co-occurrence analysis of keywords, the results found that 669 keywords divided into 11 clusters. The analysis which uses bibliometric analysis develops the status of internet financial reporting, this is a research field in a precise way through the visualization of emerging trend and currently focused on topics. The results of analysis also have recommended some variables which can be used in further research, and it is very helpful to find knowledge basis and detect the future research directions in this area.
    Keywords:  Bibliometric analysis; Internet financial reporting; VOSviewer
    DOI:  https://doi.org/10.1016/j.heliyon.2021.e08551
  8. Int J Environ Res Public Health. 2021 Dec 13. pii: 13154. [Epub ahead of print]18(24):
      Atherosclerosis is a pathological vascular state caused by the interaction of environmental and hereditary factors. Epigenetic modifications may be the bridge connecting environmental factors and genetic factors. A search for publications on the Web of Science database in the field of atherosclerosis related to epigenetics was conducted from the earliest mention to 31 December 2020. Data on total and annual publications, citations, impact factors, Hirsch (H)-index, citation times, most prolific authors, and frequently published journals were collected for quantitative and qualitative comparison. A total of 1848 publications related to epigenetics and atherosclerosis were found. The major contributing countries were the China (522, 28.23%), United States (485, 26.23%), and Germany (119, 6.44%). The greatest number of retrieved publications were published in the journal, "Arteriosclerosis, Thrombosis, and Vascular Biology" (62, 3.66%). The publication "Oxidative Stress and Diabetic Complications" was cited 2370 times. The most frequent keywords were "DNA methylation" and "LncRNA". Publications on epigenetic research in the atherosclerosis field have increased significantly every year, indicating that the study of epigenetic modifications plays an increasingly important role in understanding the pathology of atherosclerosis.
    Keywords:  DNA methylation; atherosclerosis; bibliometrics; epigenetics; publication
    DOI:  https://doi.org/10.3390/ijerph182413154
  9. Animals (Basel). 2021 Nov 26. pii: 3385. [Epub ahead of print]11(12):
      Background: Fascioliasis is a zoonotic neglected tropical disease caused by Fasciola hepatica and F. gigantica. In endemic regions, fascioliasis represents a huge problem in livestock production and significantly threatens public health. The present study was performed to assess the key bibliometric indicators, plot the global research outcome, and strive to find the research frontiers and trends in fascioliasis. Methods: A descriptive bibliometric and visualized study was conducted. The data were extracted from the Web of Science Core Collection (WoSCC) database. The WoSCC was searched using key terms covering a wide range of synonyms related to the causative agent (Fasciola) and the disease (fascioliasis). The database search was performed for the period from the inception of WoSCC until 3 October 2021. The downloaded data were exported into VOSviewer software version 1.6.17 for Windows to construct co-authorship countries, keywords co-occurrence, bibliographic coupling sources, and citation and documents network visualization. Results: A total of 4165 documents were included in this bibliometric analysis. The included documents were published between the years 1913 and 2021 from 116 countries, mainly from the United States of America (USA) (n = 482, 11.6%). The most prolific year was 2018 (n = 108). The journal that attracted the most publications was Veterinary Parasitology (n = 324), while the most productive author in this area was Rondelaud D (n = 156). In terms of total link strength (TLS), the most influential country was Spain (TLS = 236), followed by the USA (TLS = 178). Conclusion: This study is of value for veterinarians, doctors, and researchers to explore insights into research frontiers and trends in research on fascioliasis. The number of publications on fascioliasis has increased over time. Above 35% of publications have been produced by the USA, France, England, and Spain. "Fasciola hepatica" and "cattle" were the most dominant and widely used keywords. Research collaboration should be established among the researchers from developing countries with developed countries to learn new advancements and effective control strategies for fascioliasis.
    Keywords:  VOSviewer software; bibliometric analysis; fascioliasis; research trend; web of science core collection
    DOI:  https://doi.org/10.3390/ani11123385
  10. World J Gastrointest Surg. 2021 Nov 27. 13(11): 1509-1522
       BACKGROUND: One of the most popular bariatric procedures is sleeve gastrectomy, and it has become significantly more common in recent years.
    AIM: To evaluate the research activity in sleeve gastrectomy over the last two decades, and to visualize the hot spots and emerging trends in this type of bariatric surgery using bibliometric methods.
    METHODS: The Scopus database was used to search for publications related to sleeve gastrectomy. The retrieved publications were reviewed in terms of year of publication, type of study, country of origin, institutions, journals, and citation patterns by using descriptive analysis. Collaboration network and term co-occurrence analysis were visualized by using VOSviewer software.
    RESULTS: The search strategy yielded a total of 6508 publications on sleeve gastrectomy from 2001 to 2020. As regards the document type, the majority were articles (n = 5230; 80.36%), followed by reviews (n = 544; 8.36%). The top three countries are the United States, with 1983 publications (30.47%), followed by France (600; 9.22%) and Italy (417; 6.71%). The most cited publication was published in 2012 by Schauer et al in the New England Journal of Medicine (n = 1435 citations). This publication found that weight loss was greater in the sleeve gastrectomy group than in the medical therapy group. Furthermore, this study demonstrated that 12 mo of medical therapy plus bariatric surgery greatly improved glycemic regulation in obese patients with uncontrolled type 2 diabetes compared with medical therapy alone. The focus of the current literature on sleeve gastrectomy was directed toward several themes such as morbidity and potential complications, the complexity of the procedure and different surgical approaches, and diabetes and body mass index in correlation to sleeve gastrectomy.
    CONCLUSION: The number of sleeve gastrectomy publications has gradually grown over the last 20 years. This bibliometric analysis could help researchers better understand the knowledge base and research frontiers surrounding sleeve gastrectomy. In addition, future studies may focus on emerging research hotspots.
    Keywords:  Bariatric surgery; Bibliometric; Scopus; Sleeve gastrectomy; VOSviewer
    DOI:  https://doi.org/10.4240/wjgs.v13.i11.1509
  11. Healthcare (Basel). 2021 Dec 17. pii: 1749. [Epub ahead of print]9(12):
      Atopic dermatitis (AD) has been increasing in prevalence over the past few decades; however, AD has never been analyzed using a bibliometric approach. We searched for AD studies in the dermatology and allergy category of the Web of Science and SCOPUS databases using the keywords "atopic dermatitis", "eczema", and "atopy". In total, 53,460 documents were retrieved. We analyzed annual publication trends and performed keyword and co-authorship network analyses. The annual number of AD publications has increased over the years. Asthma, food allergies, the skin barrier, IgE, and epidemiology have received extensive attention. The keywords 'allergic rhinitis', 'child(ren)', 'quality of life', and 'probiotics' have become more commonly used in recent years. AD research has been led by only a few countries, such as the USA, Germany, and the UK, and longstanding research topics such as asthma, allergy, and the immune system continue to be important. We suggest that global collaborations, research in developing countries, and research that is more holistic (thus exploring how genes, the immune system, the environment, and the microbiome together impact AD) are necessary.
    Keywords:  asthma; atopic dermatitis; bibliometric analysis; immunoglobulin E; probiotics
    DOI:  https://doi.org/10.3390/healthcare9121749
  12. SICOT J. 2021 ;7 64
       BACKGROUND: The internet has changed the way we access and publish Orthopaedic literature. Traditional subscription journals have been challenged by the open access method of publication which permits the author to make their article available to all readers for free, often at a cost to the author. This has also been adopted in part by traditional subscription journals forming hybrid journals. One of the criticisms of open access publications is that it provides the author with a "pay to publish" opportunity. We aimed to determine if access to the journals impacts their influence.
    METHODS: We selected the top 40 Trauma and Orthopaedic Journals as ranked by the SCImago Rank. Each journal was reviewed and assessed for the journal quality, defined by reviewing the journal impact factor and SCImago rank; influence, defined by reviewing the top 10 articles provided by the journal for the number of citations; and cost of open access publication.
    RESULTS: Of the top 40 journals, 10 were subscription, 10 were open access, and 20 were hybrid journals. Subscription journals had the highest mean impact factor, and SCImago rank with a significant difference in the impact factor (p = 0.001) and SCImago rank (p = 0.021) observed between subscription and open access journals. No significant difference was seen between citation numbers of articles published in subscription and open access journals (p = 0.168). There was a positive correlation between the cost of publishing in an open access journal and the impact factor (r = 0.404) but a negative correlation between cost and the number of citations (r = 0.319).
    CONCLUSION: Open access journals have significantly lower quality measures in comparison to subscription journals. Despite this, we found no difference between the number of citations, suggestive of there being no difference in the influence of these journals in spite of the observed difference in quality.
    Keywords:  Citations; Open access; Orthopaedic Literature; Publications
    DOI:  https://doi.org/10.1051/sicotj/2021062
  13. Healthcare (Basel). 2021 Dec 04. pii: 1680. [Epub ahead of print]9(12):
      Nursing professionals are constantly exposed to several risk factors and high levels of stress that can affect their mental, emotional, and physical health, which can trigger burnout syndrome. This article aims to use bibliometric analysis to investigate burnout research trends among nursing professionals worldwide and to compare the contributions of different countries/institutions, scientific journals, authors, keywords, and citations. A bibliometric study was performed using the Scopus and Web of Science databases, in the period up to November 2021, aiming to search original and review articles in the English language regarding burnout in nursing professionals. The analysis was performed with a sample of 1406 articles. The most cited article indicated that 43% of nurses had high burnout scores, and a similar percentage were dissatisfied with their work. The most productive and most cited country in the world was the United States of America. Regarding the 10 most cited documents, there were no studies that could provide interventions to reduce burnout in nursing professionals, which can result in a need to develop studies on prevention capable of mitigating the problem, in view of the impacts generated on their mental, emotional, and physical health.
    Keywords:  bibliometric study; burnout syndrome; nursing professionals
    DOI:  https://doi.org/10.3390/healthcare9121680
  14. Int J Environ Res Public Health. 2021 Dec 13. pii: 13150. [Epub ahead of print]18(24):
      This study comprehensively summarizes research in the field of meditation, especially mindfulness meditation from 1900 to 2021, by analyzing the knowledge map through CiteSpace and VOSviewer software. Using "mindfulness *" or "meditation *" as the topic, articles included in the Science Citation Index Expanded and Social Sciences Citation Index were searched in the web of science core database, resulting in the selection of 19,752 articles. Over half a century ago, Deikman published the field's first article in the Journal of Nervous and Mental Disease in 1963, and publications have soared in subsequent decades. The USA is in the core position in terms of global collaboration, total publication numbers, and total citations. The Mindfulness journal ranked first for the most published articles and citations. "The benefits of being present: Mindfulness and its role in psychological well-being," written by Brown and Ryan, was the most cited article. Mindfulness, meditation, depression, intervention, stress reduction, stress, and anxiety are the top co-occurrence keywords. The timeline of cluster analysis discloses that before 2010, hypertension, cancer, mindfulness, generalized anxiety disorder, and other topics received great attention. In the decade since 2010, scholars have shown interest in meta-analysis, attention, and self-assessment, and keen attention to mindfulness-based interventions. These findings provide an important foundation to direct future research.
    Keywords:  CiteSpace; VOSviewer; bibliometric; health; meditation; mindfulness; well-being
    DOI:  https://doi.org/10.3390/ijerph182413150
  15. J Med Internet Res. 2021 Dec 20.
       BACKGROUND: Social media has been extensively used for the communication of health-related information and consecutively for the potential spread of medical misinformation. Conventional systematic reviews have been published on this topic to identify original articles and to summarize their methodological approaches and themes. A bibliometric study could complement their findings, for instance, by evaluating the geographical distribution of the publications and if they were well cited and disseminated in high impact journals.
    OBJECTIVE: The aim of the present study was to perform a bibliometric analysis of the current literature to discover the prevalent trends and topics related to medical misinformation on social media.
    METHODS: Web of Science Core Collection electronic database was accessed to identify relevant papers with the following search string: ALL=(misinformati* OR "wrong informati*" OR disinformati* OR "misleading informati*" OR "fake news*") AND ALL=(medic* OR illness* OR disease* OR health* OR pharma* OR drug* OR therap*) AND ALL=("social media*" OR Facebook* OR Twitter* OR Instagram* OR YouTube* OR Weibo* OR Whatsapp* OR Reddit* OR TikTok* OR WeChat*). Full records were exported to a bibliometric software, VOSviewer, to link bibliographic information with citation data. A term map and keyword maps were created to illustrate recurring terms and keywords.
    RESULTS: Based on the analysis of 529 papers on medical and health-related misinformation on social media, we found that the most popularly investigated social media platforms were Twitter (90), YouTube (67), and Facebook (57). Articles targeting these three platforms also had higher citations per paper (>13.7) than articles covering other social media platforms (Instagram, Weibo, Whatsapp, Reddit, and WeChat; <8.7). Moreover, social media platform-specific papers accounted for 44% of all identified publications. Investigations on these platforms had different foci. Topic preference for Twitter-based research was the investigation of cyberchondria and hypochondriasis, YouTube-based research explored tobacco smoking, whereas Facebook-based research studied vaccine hesitancy related to autism. COVID-19 was a common topic investigated across all platforms. Overall, the United States had contributions to half of all identified papers, and 80% of the top ten most productive institutions were based in this country. The identified papers were mostly published in journals of the categories public environmental and occupational health, communication, health care sciences services, medical informatics, and medicine general internal, with the top journal being the Journal of Medical Internet Research.
    CONCLUSIONS: There is a significant platform-specific topics preference for social media investigations on medical misinformation. With a large population of internet users from China, it may be reasonably expected that Weibo, WeChat, TikTok (and its Chinese version Douyin) would become more investigated in future studies. Currently these platforms present research gaps that leave their usage and information disseminated warranting further evaluation. Future studies should also include social platforms targeting non-English users to provide a wider global perspective.
    DOI:  https://doi.org/10.2196/28152
  16. Zhongguo Zhen Jiu. 2021 Dec 12. 41(12): 1410-4
      The paper retrieves and analyzes SCI articles on acupuncture-moxibustion published in the world from 1921 to 2020. It is found that the overall growth of SCI articles on acupuncture-moxibustion in both China and global countries is increasing, and the proportion of publication amount in China is increased gradually. It is believed that the articles on acupuncture-moxibustion researches from 1921 to 2020 in the world collected in SCI database indicate three stages, i.e. scattered publication, internationalization and great contribution on acupuncture-moxibustion in TCM. The paper investigates the first SCI article on acupuncture-moxibustion in the world and in China respectively and analyzes the main disciplines, research institutions and journal distribution, as well as the highly cited articles in the global countries. It is proposed that acupuncture-moxibustion research in China should reflect the academic ideological characteristics of acupuncture-moxibustion in TCM, develop the interdisciplinary research and deepen the cooperation with high-level scientific institutions so as to improve the international academic influence of acupuncture-moxibustion in TCM.
    Keywords:  SCI database; acupuncture-moxibustion; bibliometrics; literature analysis
    DOI:  https://doi.org/10.13703/j.0255-2930.20210506-0003
  17. Addict Behav Rep. 2021 Dec;14 100371
       Aims: The increase in scientific interest in so-called behavioral addictions has been growing in recent years. For this reason, the aim of our study is to use bibliometric techniques to identify where and with what intensity these behaviors are being studied.
    Methods: In October 2020, we conducted a search in the Web of Science Core Collection using a search equation designed to retrieve the articles that combine the general keywords of addiction with specific terms of the 7 groups of behavioral addictions analyzed (gambling; gaming; information and communication related disorders; and the so-called somatic addictions related to sex, shopping, food and sports). Articles published from 1995 to 2019 were included.
    Results: We found 9199 distinct articles. Gambling was the most studied addiction, but Information and Technology Communication-related disorders (ITC) had the highest growth rate over the span of five five-year periods, followed by gaming and food addiction. In general, there was a growth rate of 130.46% in the research on behavioral addiction issues. By geographical region, the United States was the most productive country regarding all addictions, but Oceania had the highest proportion of publications per million population. There was a clear interest among Asian countries in studying problems related to ITC and gaming problems.
    Conclusions: The importance of the seven behavioral addictions analyzed according to their growth rate in scientific research fields over the last 25 years was confirmed in our study. In addition, the differences in interest by geographical region show us that it is important to delve deeper into cultural particularities to better understand this phenomenon.
    Keywords:  Behavioral addiction; Bibliometric study; Food addiction; Gambling; Gaming; Geographical differences; ITC-related disorders; Sex addiction; Shopping addiction; Sports addiction
    DOI:  https://doi.org/10.1016/j.abrep.2021.100371
  18. J Med Chem. 2021 Dec 21.
      A bibliometric study of authors across medicinal chemistry journals over 20 years reveals important trends. Most United States (US) based authors are assigned as racially/ethnically Asian or White; few are Black or Hispanic. More US coauthors have the same race/ethnicity as the corresponding author than expected. The percentage of female authors increased globally, but only slowly. Since 2010, the number of female and male authors declined by 9% and 30%, respectively. Geographically, most authors are male except in Italy where there is gender balance. Gender homophily is observed globally. Geographically, the discipline is now more widely practiced. Article output doubled from 2000 to 2010 with a large increase in articles from China. China excepted, output has since declined. The average number of authors per article rose by a third since 2000. The value of high diversity groups in education, research, and industry cannot be overstated. We recommend diversity is addressed by every medicinal chemist.
    DOI:  https://doi.org/10.1021/acs.jmedchem.1c01632
  19. Soc Sci Humanit Open. 2021 ;4(1): 100165
      With the rapid global spread of the COVID-19 pandemic, researchers from diverse fields of study have contributed markedly in different research aspects. Considering the substantial economic significance of the pandemic at the micro and macro level throughout the world, we review the scientific publications in the discipline of Economics. To draw a broad inference, we analyze a total of 1,636 scientific publications starting from 1974, which covers the period of earlier pandemics or epidemics that have a close association with COVID-19 using bibliometric analysis. Our analysis and mapping reveal key information related to the contributors at different levels, including author, institution, country, and publication sources. Besides, we identify the historical concentration of research using scientific clustering and illustrate transformations at different times. Moreover, recognizing the underlying inadequacy of economics research, we propose several areas of future research. Our findings and suggestions are expected to act as a roadmap to potential research opportunities and notable implications for business and policymakers.
    Keywords:  Bibliometrics; COVID-19; Coronavirus; Economics; Epidemic; Pandemic
    DOI:  https://doi.org/10.1016/j.ssaho.2021.100165
  20. Int J Environ Res Public Health. 2021 Dec 10. pii: 13065. [Epub ahead of print]18(24):
      Many scholars have conducted in-depth research on the theme of land use change and food security, and formed fruitful research results, but there is a lack of quantitative analysis and comprehensive evaluation of research achievements. Therefore, based on the relevant literature on the theme of land use change and food security in the core collection of the Web of Science (WOS) database, this paper takes the advantage of CiteSpace and VOSviewer bibliometric software to draw the cooperative network and keyword cooccurrence map to analyze the research progress and frontier. The results reveal that: (1) The research started in 1999 and can be divided into three stages: initial research, rapid development, and a stable in-depth stage. This topic has increasingly become a research hotspot in the academic community. (2) The distribution of research institutions is concentrated and forms a small cluster, and the research networks between developed and developing countries have been established, and developed countries are in the core position, but the cooperation network is not prominent. (3) The research content is becoming increasingly organized and systematic, and the research hot topics are divided into seven aspects. (4) The research area of the subject covers multiple levels, such as global, national, and specific natural geographical regions, and has formed a research system of geographic information technology and satellite remote sensing technology. It also presents the trend of cross integration with economics, land management and soil science. In the future, theoretical innovation still needs to be strengthened, and we should strengthen the research on the impact of agricultural chemical fertilizers on food security and study the impact of urban expansion on land use change.
    Keywords:  CtieSpace; VOSviewer; food security; land use change; progress and frontier; visual analysis
    DOI:  https://doi.org/10.3390/ijerph182413065
  21. Int J Environ Res Public Health. 2021 Dec 08. pii: 12966. [Epub ahead of print]18(24):
      Natural resources are becoming scarcer and, together with the growth of the population, a widespread situation of overexploitation is inevitable that has become the biggest challenge for today's world. In this context, the agri-food sector has a considerable environmental impact in terms of water and energy consumption. For about two decades, the Water-Energy-Food Nexus (WEF) Nexus has been trying to address this problem, focusing on efficient interrelationships among these dimensions. The objective of this work is to analyse the evolution of research on WEF Nexus in the agri-food sector and its development in scientific databases. For that purpose, a bibliometric study was carried out with publications obtained from the Scopus database, examining the main journals, authors, institutions, countries, subject areas, funding sponsors, and keywords. Moreover, a final section is specifically dedicated to the agri-food innovations in WEF Nexus in order to explore innovative aspects to effectively overcome technical barriers that hinder a real implementation of the Nexus approach. The results show that, over the past decade, Nexus research in the agri-food sector has been growing exponentially. The top country in this field is USA, the most studied area is environmental science, and the most relevant keywords are "energy use", "water budget", "food security", "sustainable development", and "water resources".
    Keywords:  Water–Energy–Food Nexus; agri-food sector; bibliometric analysis; innovation practices; sustainability
    DOI:  https://doi.org/10.3390/ijerph182412966
  22. Orphanet J Rare Dis. 2021 Dec 20. 16(1): 517
       BACKGROUND: Systemic sclerosis (SSc) is a rare detrimental disease warranting global research efforts. Evaluating how socio-economic factors impact country research output on SSc could help to identify solutions advancing research.
    METHODS: Publication production on SSc during 1969-2018 and data for structural and policy factors for WHO member countries were collected from public sources. Associations between SSc research output and country-level factors were investigated through panel regression. Difference-in-differences analysis further assessed the causal effects of rare disease legislation.
    RESULTS: SSc publications demonstrated exponential growth (r = 0.9410, as against an r = 0.8845 after linear adjustment), but were concentrated in high-income countries (HICs). Ten countries, nine of which were HICs, published 12,261 (77.5%) SSc publications but another 87 countries produced none. Gross domestic products (GDP), population and expenditure on research and development were positively associated with SSc publications (p < 0.001). Higher health expenditure was only found to be associated with increased SSc publications in HICs (p < 0.001). Rare disease legislation increased annual publication production by 62.8% (95% CI 0.390-0.867; p < 0.001) averagely. In middle-income countries (MICs), the effect was especially swift and lasting. No significant impact was found with GDP per capita, female percentage, and political indicators.
    CONCLUSIONS: SSc research output increased over time with substantial country disparities. Effective health policies facilitating research should be expanded especially among MICs to accelerate research advancement.
    Keywords:  Bibliometrics; Research output; Systemic sclerosis
    DOI:  https://doi.org/10.1186/s13023-021-02149-w
  23. Int J Cardiol. 2021 Dec 15. pii: S0167-5273(21)02013-1. [Epub ahead of print]
       BACKGROUND: Retractions of erroneous and fraudulent papers from the biomedical literature continue to be a major concern. The aim of this analysis is to summarize trends of retractions in the cardiovascular literature over the past four decades.
    METHODS: A review of the Retraction Watch database for retracted articles published between 1978 and 2020 in the cardiovascular literature was performed. Retractions with the term "medicine" in the subject code were selected. Titles and abstracts were reviewed and only retractions of articles in cardiovascular medicine and surgery were included.
    RESULTS: 459 retraction notices published in 228 journals were identified. The number of retractions increased with time from 1 in 1991 to 48 at the end of 2019 (P < 0.001). Overall, the yearly percentage of retraction increased during the study period (P < 0.001) but decreased after 2015. China had the highest percentage of retractions when compared to other countries (P < 0.001). The majority of articles were retracted for scientific misconduct (n = 289, 63.0%); retractions due to scientific misconduct increased significantly over the study period (P = 0.04) but decreased after 2015. The median time from publication to retraction was 1.4 years (interquartile range [IQR]: 0.6-3.8) and decreased significantly over time (P < 0.001). The median number of citations of retracted articles was 8.0.
    CONCLUSIONS: The number of retractions and the yearly percentage of retraction in the cardiovascular literature increased significantly during the study period, although a decrease was seen after 2015. Scientific misconduct represents the most common reason for retraction, although a reduction has been observed in the last five years.
    Keywords:  Cardiovascular literature; Retraction; Scientific misconduct
    DOI:  https://doi.org/10.1016/j.ijcard.2021.12.021
  24. Qatar Med J. 2021 ;2021(3): 43
      It is with great pride that we celebrate the 50th issue of Qatar Medical Journal (QMJ) that has achieved significant growth recently. Our mission is to encourage authors to submit high-quality and innovative research promoting medical advancements. In the past two years, manuscripts submissions have tripled in number and were enriched by a more diverse pool of authors with global representation, resulting in an increase in the number of published issues moving from being a biannual to a triannual journal. Additionally, the number of articles published in an issue has doubled. QMJ continues to be an open-access peer-reviewed journal, publishing original research work, reviews, editorials, and case reports that are particularly relevant to medicine and free of charge to authors. It is indexed in several renowned and highly ranked platforms such as PubMed Central, Scopus, Scimago, Google Scholar, and the Directory of Open Access Journals. It was also recently indexed in the World Health Organization's Index Medicus for the Eastern Mediterranean Region (IMEMR). We look forwards to becoming the highest-rated medical journal, in terms of impact factor, regionally.
    DOI:  https://doi.org/10.5339/qmj.2021.43
  25. Int J Environ Res Public Health. 2021 Dec 11. pii: 13095. [Epub ahead of print]18(24):
       BACKGROUND: The new media provides a convenient platform to access, use and exchange health information. And as a special group of health care, maternal health care is still of international concern due to their high mortality rate. Scientific research is a good way to provide advice on how to improve maternal health through stringent reasoning and accurate data. However, the dramatic increase of publications, the diversity of themes, and the dispersion of researchers may reduce the quality of information and increase the difficulty of selection. Thus, this study aims to analyze the research progress on maternal health under the global new media environment, exploring the current research hotspots and frontiers.
    METHODS: A scientometric analysis was carried out by CiteSpace5.7.R1. In total, 2270 articles have been further analyzed to explore top countries and institutions, potential articles, research frontiers, and hotspots.
    RESULTS: The publications ascended markedly, from 29 in 2008 to 472 publications by 2020. But there is still a lot of room to grow, and the growth rate does not conform to the Price's Law. Research centers concentrated in Latin America, such as the University of Toronto and the University of California. The work of Larsson M, Lagan BM and Tiedje L had high potential influence. Most of the research subjects were maternal and newborn babies, and the research frontiers were distributed in health education and psychological problems. Maternal mental health, nutrition, weight, production technology, and equipment were seemingly hotspots.
    CONCLUSION: The new media has almost brought a new era for maternal health, mainly characterized by psychological qualities, healthy and reasonable physical conditions and advanced technology.
    Keywords:  bibliometric analysis; cited reference analysis; hotspots; maternal health; new media; structural variation analysis
    DOI:  https://doi.org/10.3390/ijerph182413095
  26. Elife. 2021 Dec 24. pii: e72737. [Epub ahead of print]10
      Disagreement is essential to scientific progress but the extent of disagreement in science, its evolution over time, and the fields in which it happens remain poorly understood. Here we report the development of an approach based on cue phrases that can identify instances of disagreement in scientific articles. These instances are sentences in an article that cite other articles. Applying this approach to a collection of more than four million English-language articles published between 2000 and 2015 period, we determine the level of disagreement in five broad fields within the scientific literature (biomedical and health sciences; life and earth sciences; mathematics and computer science; physical sciences and engineering; and social sciences and humanities) and 817 meso-level fields. Overall, the level of disagreement is highest in the social sciences and humanities, and lowest in mathematics and computer science. However, there is considerable heterogeneity across the meso-level fields, revealing the importance of local disciplinary cultures and the epistemic characteristics of disagreement. Analysis at the level of individual articles reveals notable episodes of disagreement in science, and illustrates how methodological artifacts can confound analyses of scientific texts.
    Keywords:  citation analysis; disagreement; meta-research; metascience; natural language processing; none
    DOI:  https://doi.org/10.7554/eLife.72737
  27. J Korean Med Sci. 2021 Dec 20. 36(49): e345
      During the coronavirus disease 2019 (COVID-19) pandemic, publications on the disease have exploded globally. The present study analyzed PubMed and KoreaMed indexed COVID-19 publications by Korean researchers from January 1, 2020 to August 19, 2021. A total of 83,549 COVID-19 articles were recorded in PubMed and 1,875 of these were published by Korean authors in 673 journals (67 Korean and 606 overseas journals). The KoreaMed platform covered 766 articles on COVID-19, including 612 by Korean authors. Among the Journal of Korean Medical Science (JKMS) articles on COVID-19, PubMed covered 176 and KoreaMed 141 documents. Korean researchers contributed to 2.2% of global publications on COVID-19 in PubMed. The JKMS has published most articles on COVID-19 in Korea.
    Keywords:  Bibliographies as Topic; COVID-19; Journal of Korean Medical Science; Korean Researcher; Periodicals as Topic; Publications
    DOI:  https://doi.org/10.3346/jkms.2021.36.e345
  28. Zhongguo Zhong Yao Za Zhi. 2021 Nov;46(21): 5475-5485
      This study aimed to provide researchers with a better understanding of the research status, progress and problems of Chinese medicine-induced kidney injury. The mapping knowledge domain(MKD) was chosen to visualize the research process, hotspots,and frontiers, thus providing a reference for follow-up research. The relevant articles were retrieved from China National Knowledge Infrastructure(CNKI) from its inception to November 20, 2020, and 683 were finally included for visualization, with a knowledge map covering the keywords, research institutions and authors plotted by Cite Space. Since 2006, the annual number of published articles regarding Chinese medicine-induced kidney injury has steadily declined. The top five keywords sorted by frequency of co-occurrence were tubulointerstitial nephritis(TIN), aristolochic acid(AA), Akebiae Caulis, experimental research, and descriptive research. Akebiae Caulis appeared at the highest frequency of co-occurrence among Chinese medicines and exhibited the highest burst intensity. The burst ended in 2020, when the Chinese medicine with the highest burst intensity changed to Tripterygii wilfordii and its preparations. It could be seen that Akebiae Caulis was the hotspot in the research of Chinese medicine-induced kidney injury, and T. wilfordii became the research frontier. The current research has mainly focused on &quot; organic anion transporters&quot; and &quot; metabolomics&quot;. The decline in articles about Chinese medicine-induced kidney injury was attributed to the reduced clinical case reports after the in-depth study of Chinese medicine-induced kidney injury. However, more clinical studies need to be conducted based on the concept and method of pharmacovigilance to construct a pharmacovigilance system of Chinese medicine for actively and passively monitoring and collecting the clinical cases with Chinese medicine-induced kidney injury, figuring out the incidence and characteristics of adverse reactions caused by Chinese medicine, and carrying out comprehensive and multi-dimensional safety research.
    Keywords:  Chinese medicine; Cite Space; bibliometric science; kidney injury; safety
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20210413.502
  29. J Craniofac Surg. 2021 Dec 20.
       ABSTRACT: Facial paralysis can impair one's ability to form facial expressions that are congruent with internal emotion. This hinders communication and the cognitive processing of emotional experience. Facial reanimation surgery, which aims to restore full facial expressivity is a relatively recent undertaking which is still evolving. Due in large part to published techniques, refinements, and clinical outcomes in the scientific literature, consensus on best practice is gradually emerging, whereas controversies still exist.Taking stock of how the discipline reached its current state can help delineate areas of agreement and debate, and more clearly reveal a path forward. To do this, the authors have analyzed the 50 seminal publications pertaining to facial reanimation surgery. In longstanding cases, the free gracilis transfer emerges as a clear muscle of choice but the nerve selection remains controversial with prevailing philosophies advocating cross facial nerve grafts (with or without the support of an ipsilateral motor donor) or an ipsilateral motor donor only, of which the hypoglossal and nerve to masseter predominate. The alternative orthodoxy has refined the approach popularized by Gillies in 1934 and does not require the deployment of microsurgical principles. Although this citation analysis does not tell the whole story, surgeons with an interest in facial reanimation will find that this is a good place to start.
    DOI:  https://doi.org/10.1097/SCS.0000000000008436
  30. Int J Environ Res Public Health. 2021 Dec 09. pii: 13003. [Epub ahead of print]18(24):
      This paper used 1526 works from the literature on disaster risk perception from 2000 to 2020 in the Web of Science core collection database as the research subject. The CiteSpace knowledge graph analysis tool was used to visual analyze the country, author, institution, discipline distribution, keywords, and keyword clustering mapping. The paper drew the following conclusions. Firstly, disaster risk perception research has experienced three stages of steady development, undulating growth, and rapid growth. Secondly, the field of disaster risk perception was mainly concentrated in the disciplines of engineering, natural science, and management science. Thirdly, meteorological disasters, earthquakes, nuclear radiation, and epidemics were the main disasters in the field of disaster risk perception. Residents and adolescents were the main subjects of research in the field of disaster risk perception. Fourthly, research on human risk behavior and risk psychology and research on disaster risk control and emergency management were two major research hotspots in the field of disaster risk perception. Finally, the research field of disaster risk perception is constantly expanding. There is a trend from theory to application and multi-perspective combination, and future research on disaster risk perception will be presented more systematically. The conclusion can provide a reference for disaster risk perception research, as well as directions for future research.
    Keywords:  CiteSpace; disaster risk perception; knowledge graph; visual analysis; web of science
    DOI:  https://doi.org/10.3390/ijerph182413003
  31. Acta Dermatovenerol Alp Pannonica Adriat. 2021 Dec;30(4): 127-128
      Next spring, we will celebrate 30 years since the first issue of Acta Dermatovenerologica Alpina, Pannonica et Adriatica (Acta Dermatovenerol APA) was published and, to our astonishment and disappointment, it seems that the goal we have long awaited (and worked hard for)-obtaining an official impact factor (IF)-is nowhere in sight. Every application for an IF has been met with various reasons why our journal does not fulfill the criteria for inclusion in the Science Citation Index Expanded (SCIE). Given the highly non-transparent evaluation process, we conclude that there probably really is no room for small and independent journals in the world of publishing giants and commercial interests. Although disheartened, we will continue our long-established tradition of providing open-access and quality content in dermatology and sexually transmitted infections for researchers and clinicians in the region and worldwide because science should be open and committed to teamwork.
  32. Int J Environ Res Public Health. 2021 Dec 09. pii: 13008. [Epub ahead of print]18(24):
      Since the 1970s, health communication (HC) has attracted widespread attention from practitioners and researchers in various fields in China, leading to the production of a vast array of literature. In order to reveal the current state, popular themes, and research frontiers of HC research, this study employed the CiteSpace software to conduct a comprehensive review based on 1505 HC publications from 1992 to 2021 retrieved from the China National Knowledge Infrastructure (CNKI) database. The results demonstrated that (1) the number of HC publications has experienced an annual increase over the past 20 years, albeit with certain inverted S-shaped fluctuations and (2) the most prolific authors mainly included Wang L.Y., Zhang Z.L., and Wang Y.L., while well-known universities played a leading role in HC research in China. A significant finding was that a stable core group of authors or institutional has been not formed in the HC field. Furthermore, (3) research hotspots included health education, new media, health literacy, health information, animal husbandry and veterinary medicine (AHVM), the doctor-patient relationship, and public health emergencies. Additionally, the development of the field could be divided into four stages, indicating a significant shift in HC research from focusing on medicine and public health issues towards communication issues. Finally, (4) new research frontiers have mainly included the WeChat official account and Health China.
    Keywords:  China; CiteSpace; development process; health communication; research frontier; research hotspots
    DOI:  https://doi.org/10.3390/ijerph182413008
  33. Per Med. 2022 Jan;19(1): 1-4
      
    Keywords:  COVID-19; altmetrics; demographics; genetics; healthcare; impact factor; personalized medicine; readership; social media; top content
    DOI:  https://doi.org/10.2217/pme-2021-0138
  34. Molecules. 2021 Dec 15. pii: 7605. [Epub ahead of print]26(24):
      As coffee consumption is on the rise, and the global coffee production creates an excess of 23 million tons of waste per year, a revolutionary transition towards a circular economy via the transformation and valorization of the main by-products from its cultivation and preparation (Coffee Husk (CH), Coffee Pulp (CP), Coffee Silverskin (CS), and Spent Coffee Grounds (SCG)) is inspiring researchers around the world. The recent growth of scholarly publications in the field and the emerging applications of coffee by-products published in these scientific papers encourages a systematic review to identify the knowledge structure, research hotspots, and to discuss the challenges and future directions. This paper displays a comprehensive scientometric analysis based on 108 articles with a high level of influence in the field of coffee by-products and their applications. According to our analysis, the research in this field shows an explosive growth since 2017, clustered in five core applications: bioactive compounds, microbial transformation, environmental applications, biofuels from thermochemical processes, and construction materials.
    Keywords:  applications; coffee by-products; coffee husk; coffee pulp; coffee silverskin; scientometric analysis; spent coffee grounds
    DOI:  https://doi.org/10.3390/molecules26247605
  35. J Vasc Surg. 2021 Dec 16. pii: S0741-5214(21)02343-0. [Epub ahead of print]
       OBJECTIVES: Spin is the manipulation of language that distorts the interpretation of objective findings. The purpose of this study is to describe the characteristics of spin found in statistically nonsignificant randomized controlled trials (RCT) comparing carotid endarterectomy (CEA) to carotid artery stenting (CAS) for carotid stenosis (CS), and endovascular repair (EVAR) to open repair (OR) for abdominal aortic aneurysms (AAA).
    METHODS: A search of MEDLINE, EMBASE, and the Cochrane Controlled Register of Trials was performed in June 2020 for studies published describing AAA or CS. All phase three RCTs with nonsignificant primary outcomes comparing OR to EVAR or CEA to CAS were included. Studies were appraised for the characteristics and severity of spin using a validated tool. Binary logistic regression was performed to assess the association of spin grade to (1) funding source (commercial vs non-commercial) and (2) the publishing journal's impact factor.
    RESULTS: Thirty-one of 355 articles captured were included for analysis. Spin was identified in nine abstracts (9/18) and 13 main texts (13/18) of AAA articles and seven abstracts (7/13) and ten main texts (10/13) of CS articles. For both AAA and CS articles, spin was most commonly found in the manuscript discussion section, with the most commonly employed strategy being the interpretation of statistically nonsignificant primary results to show treatment equivalence or rule out adverse treatment effects. Increasing journal impact factor was associated with a statistically significant lower likelihood of spin in the study title or abstract conclusion (βOR = 0.96, 95% CI: 0.94 - 0.98, p < 0.01) while no significant association could be found with funding source (βOR = 1.33, 95% CI: 0.30-5.92, p = 0.71).
    CONCLUSIONS: A large proportion of statistically nonsignificant RCTs contain interpretations that are inconsistent with their results. These findings should prompt authors and readers to appraise study findings independently and to limit the use of spin in study interpretations.
    DOI:  https://doi.org/10.1016/j.jvs.2021.09.051
  36. ESMO Open. 2021 Dec;pii: S2059-7029(21)00243-X. [Epub ahead of print]6(6): 100281
       BACKGROUND: Exploratory research showed that female oncologists are frequently under-represented in leadership roles. European Society for Medical Oncology (ESMO) Women for Oncology (W4O) therefore implemented gender equality programs in career development and established international studies on female representation at all stages of the oncology career pathway.
    METHODS: For 2017-2019, data were collected on (i) first and last authorship of publications in five major oncology journals and (ii) representation of women in leadership positions in oncology-as invited speakers at National/International congresses, board members or presidents of National/International societies and ESMO members. The 2015/2016 data from the first published W4O Study were incorporated for comparisons.
    RESULTS: Across 2017-2019, female oncologists were significantly more likely to be first than last authors (P < 0.001). The proportion of female first authors was similar across years: 38.0% in 2017, 37.1% in 2018, 41.0% in 2019 (P = 0.063). The proportion of female last authors decreased from 30.4% in 2017 to 24.2% in 2018 (P = 0.0018) and increased to 28.5% in 2019 (P = 0.018). Across 2015-2019, invited speakers at International/National oncology congresses were significantly less likely to be female than male (P < 0.001; 29.7% in 2015 to 36.8% in 2019). Across 2016-2019, board members of International/National oncology societies were significantly less likely to be female than male (P < 0.001; 26.8% in 2016 to 35.8% in 2019). There were statistically significant increasing trends in female speakers and board members across the study periods (P < 0.001 for both). Societies with a female president had a higher proportion of female board members across these periods (P = 0.026).
    CONCLUSIONS: Reported progress towards gender equality in career development in oncology is real but slow. Women in leadership positions are essential for encouraging young women to aspire to and work towards similar or greater success. Therefore, continued monitoring is needed to inform ESMO W4O initiatives to promote gender balance at all stages of the career pathway.
    Keywords:  ESMO Women for Oncology; female leadership; gender equality; gender gap; women representation
    DOI:  https://doi.org/10.1016/j.esmoop.2021.100281
  37. Sci Prog. 2021 Oct;104(4): 368504211061974
      This study aimed to identify the relationships between the keywords of research on metabolic syndrome in cancer survivors and the entire knowledge research structure, through topic extraction from a macro perspective. From six electronic databases, 918 studies published between 1996 and 2019 were identified and reviewed, and 365 were included. Keyword network analysis and topic modeling were applied to examine the studies. In keyword network analysis, "obesity," "treatment," "breast cancer," "body mass index," and "prostate cancer" were the major keywords, whereas "obesity" and "breast" were the dominant keywords and ranked high in frequency, degree centrality, and betweenness centrality. In topic modeling, five clustered topics emerged, namely metabolic syndrome component, post CTX(chemotherapy) sequence, prostate-specific antigen-sensitive plot, lifestyle formation, and insulin fluctuation. Topic 2, post CTX sequence, showed the highest salience in earlier studies, but this has decreased over time, and the themes of the studies have also broadened. This study may provide critical basic data for determining the changing trends of research on metabolic syndrome in cancer survivors and for predicting the direction of future research through the visualization of the effects and interactions between the major keywords in research on metabolic syndrome in cancer survivors.
    Keywords:  Metabolic syndrome; cancer survivors; research analysis; social network analysis; topic modeling
    DOI:  https://doi.org/10.1177/00368504211061974