bims-evares Biomed News
on Evaluation of research
Issue of 2021–11–28
fifty-two papers selected by
Thomas Krichel, Open Library Society



  1. Front Aging Neurosci. 2021 ;13 722944
      Background: For measuring the impact in clinical and scientific research, the citation count of the articles is used in the bibliometric analysis, although there is no comprehensive summary of neurodegenerative disease research. This study intends to provide the neuroscientists and investigators with a practical reference guide to appraise the most important and influential articles written on this subject through a macroscopic view of the research activities on neurodegenerative diseases. Materials and Methods: The Clarivate Analytics Web of Science was searched in July 2020. To ensure the breadth of the search scope, the search terms were confirmed as "multiple sclerosis" (MS) or "amyotrophic lateral sclerosis" (ALS) or "Parkinson's" or "Alzheimer's" or "Huntington's" or "neurodegenerative." After excluding completely unrelated articles, the top-cited articles were collected and evaluated from special characteristics. The data analysis was performed using SPSS 18.0. The articles were characterized by citation number, publication year, topic, study type, authorship, journal, country, and institute of responding author and foundation. Results: The query identified 593,050 articles. A total of 45% of the top-cited articles were published during 2000-2009, followed by 30 articles from 1990-1999. Diagnosis and pathology were the main research categories (n = 62). Alzheimer's disease (AD) was the main study topic (n = 43). Meanwhile, the United States confirmed the tremendous impact on the field of neurodegenerative diseases. Notably, 69 of 100 articles were studied in the United States, and the National Institutes of Health sponsored 49 articles. There were only 22 articles that can be divided by evidence level. No article was categorized as level 1 evidence. In the journal list with multiple articles, seven of 15 were general journals. The 58 authors, who contributed to more than one article, have been identified by VOSviewer, and the clusters of authors reveal the evolution of research focus in neurodegenerative diseases. Conclusions: This study analyzed the bibliometric characteristics and connections of 100 top-cited articles in the field of neurodegenerative diseases in the Web of Science. Their main outcomes were as follows: First, the pathology and diagnostic researches took a major role in top-cited articles while the therapy articles are relatively less. Second, the United States confirmed the tremendous impact on the field of neurodegenerative diseases. Third, researchers also submitted their researches to general journals, not just focused on specialty journals.
    Keywords:  aging neuroscience; bibliometric analysis; comparative scientometric analysis; neurodegenerative diseases; visualization; women in neuroscience
    DOI:  https://doi.org/10.3389/fnagi.2021.722944
  2. Int Endod J. 2021 Nov 24.
       AIM: To identify the top 100 most-cited case reports and case series published in Endodontic journals and to analyse their bibliometric characteristics.
    METHODOLOGY: The Clarivate Analytics' Web of Science (WoS), Scopus, and PubMed databases were used to identify the top 100 most-cited case reports and case series in Endodontic journals. Complete bibliographic records of the selected case reports and case series were exported in plain text or BibTeX format and imported into the R environment for statistical computing and graphics. The following parameters were then analysed: names and affiliations of the authors, title, year of publication, journal of publication, first author, corresponding author, literature cited within reports, language, citation counts, impact factor of the journal, keywords, Keywords Plus, and research topic.
    RESULTS: In total, 88 case reports and 12 case series published in English between 1977 and 2016 were identified as the most-cited reports in the field of Endodontics. The terms 'case report(s)' or 'case series' were not included in the title of 57 articles. The number of authors per report ranged from one to seven, with the average number of co-authors per report being 3.14. The most cited author was M Trope (University of Pennsylvania, USA). The University of Washington and Private Practice, Cetraro, Italy were the most productive institutions. The country whose case reports received the largest total number of citations was the USA. The largest number of the most-cited reports appeared in 2002, 2004, and 2007 (n=7, respectively). According to the WoS database, the total number of citations ranged from 42 to 453, with the average number of citations per report being 79.97. The majority of the top 100 most-cited articles were published in the Journal of Endodontics and the International Endodontic Journal. The most frequently used author keywords were revascularization and mineral trioxide aggregate. The majority of the case reports and case series dealt with topics related to pulp regeneration.
    CONCLUSION: This bibliometric study provides a comprehensive overview on the progress, trends and current directions in clinical practice within the field of Endodontics.
    Keywords:  Bibliometrics; Endodontics; case reports; case series; citations
    DOI:  https://doi.org/10.1111/iej.13668
  3. Indian J Orthop. 2021 Oct;55(5): 1326-1334
       Background: Due to the increasing number of joint arthroplasty operations, surgeons have begun to devote more attention to the problem of periprosthetic osteolysis. In recent years, numerous studies have focussed on periprosthetic osteolysis, but there have been no relevant bibliometric studies.
    Methods: We searched the Web of Science database for relevant articles concerning periprosthetic osteolysis published from 1965 to 2021. The following data were extracted: authors' name, article title, publication journal, impact factor (IF) of the journal in the publication year, keywords, topic of the article, publication country/region, the sum of times cited, H-index and funding sources. VOSviewer and Excel 2019 were used to conduct the bibliometric study and visualise the analysis.
    Results: A total of 1255 publications were included. In all selected articles, "orthopaedics" became the dominant topic (662 of 1255, 52.75%). The most productive years were 2018 and 2019, with a total of 83 publications. The Journal of Arthroplasty published the most articles on periprosthetic osteolysis (110 publications). The United States of America published the most articles (525, 41.83%). The latest keywords "continuous intramedullary infusion", "erythromycin", "autophagy", "bone-resorbing cells" and "proinflammatory cytokines" both appeared in five articles in 2017.
    Conclusion: This bibliometric study showed that there is a growing trend in published articles related to periprosthetic osteolysis. Journal of Arthroplasty was the top productive journal on periprosthetic osteolysis. The United States of America dominates studies of periprosthetic osteolysis. "Continuous intramedullary infusion", "erythromycin", "autophagy", "bone-resorbing cells" and "proinflammatory cytokines" may be new research hotspots in the field of periprosthetic osteolysis.
    Keywords:  Bibliometric study; Periprosthetic osteolysis; Total joint arthroplasty; VOSviewer
    DOI:  https://doi.org/10.1007/s43465-021-00462-x
  4. Indian J Orthop. 2021 Oct;55(5): 1335-1347
       Background: Revision total knee arthroplasty (TKA) is a longstanding area of research interest in orthopedics due to its increasing global demand and associated technical challenges. The present study aims to analyze and present the current state of research and trends in this active field.
    Methods: Articles on revision TKA published from inception to 2018 were retrieved from Web of Science. Bibliometric analysis was conducted using the metadata of the included articles. Visualized analysis was conducted using VOSviewer software to reveal global trends in revision TKA research, through analyses of bibliographic coupling, co-authorship, co-citation and co-occurrence.
    Results: A total of 6027 articles were included. The number of publications and relative research interest in the field of revision TKA displayed strong upward growth over the time period examined. The USA had the highest number of citations for publications in this field, as well as the highest H-index. Studies in the field could be categorized into five clusters: prosthesis design, periprosthetic fracture, periprosthetic joint infection, risk factors for revision TKA, and survivorship of implants. Studies focused on infection and risk factors for revision TKA are likely to become the most popular research topics in the field.
    Conclusion: Global trends over the past few years suggest that the field of revision TKA research will continue to grow and lead to increasing rates of publication output over the coming years. Future developments in the field will likely include more preventative and etiological studies relating to revision TKA.
    Keywords:  Bibliometrics; Global trend; Revision; Total knee arthroplasty; Visualized study
    DOI:  https://doi.org/10.1007/s43465-021-00390-w
  5. Antibiotics (Basel). 2021 Nov 18. pii: 1412. [Epub ahead of print]10(11):
      The relative citation rate (RCR) is a normalized article-level metric useful to assess the impact of research articles. The objective of this bibliometric study is to identify and analyze, in root canal disinfection, the 100 articles having the highest RCRs in the period 1990-2019, then compare them with the top 100 articles most cited. A cross-sectional study was performed, and the search strategy ((Disinfection AND root canal) AND (("1990/01/01"[Date-Publication]: "2019/12/31"[Date-Publication]))) relied on PubMed (n = 4294 documents), and article data were downloaded from the iCite database. The 100 articles with the highest RCRs and the top 100 cited were selected and evaluated in bibliometric terms. Among the 100 articles with the highest RCRs, there were no differences in the three decades for RCRs values, but there were in citations, being 2000-2009 the most cited. The USA was the predominant country (n = 30), followed by Brazil (n = 14). The most frequent study designs were reviews (n = 27) and in vitro (n = 25) and ex vivo (n = 24) studies. All subfields were well represented, although they varied over time. In 2010-2019, regenerative procedures and irrigation/disinfection techniques were predominant. Considering the RCR's top 100 articles, 76 were common with the 100 most cited articles. Using the RCR metric allowed us to identify influential articles in root canal disinfection, a research field with topics of significance that fluctuate over time. Compared to citations, RCR reduces the time from publication to detection of its importance for the readership and could be a valid alternative to citation counts.
    Keywords:  National Institutes of Health; article-level; bibliometrics; citation impact; citations; endodontics; field-normalization; relative citation ratio; root canal disinfection; time-normalization
    DOI:  https://doi.org/10.3390/antibiotics10111412
  6. Cell J. 2021 Oct;23(5): 523-531
       Objective: We performed this bibliometric analysis to identify global scientific research on the SARS-CoV-2 vaccines.
    Materials and Methods: This bibliometric analysis study inclusive search of English-language publications related to the SARS-CoV-2 vaccines was conducted in the Scopus, PubMed, and Dimensions databases without year limitations. The results of bibliometric analysis comprised a time-dependent citation density trend, the name of the journal, journal impact factor (IF), year of publication, type of article, category, subscription or affiliation, co-authorship, and cooccurrence network.
    Results: A study of the scientific literature from three databases (Scopus, PubMed, Dimensions) shows that investigators have focused more on studying the structure of the coronavirus at different levels (organismic, cellular, and molecular). In addition, the method of virus penetration into the cell and features of the influence of coronavirus on animals are well-studied. Various methods and strategies are being used to develop the vaccines, including both animal-tested methods and computer models. The Dimensions database is the most representative in terms of coverage of research on development of the SARS-CoV-2 vaccines.
    Conclusion: This research is a scientific investigation based on bibliometric analysis of papers related to the SARS-CoV-2 vaccines. The Dimensions database provides the most representative research coverage on the creation of a vaccine against coronavirus. It is characterized by a large number of formed verbose terms (length of more than four words) related to coronavirus, which makes it possible to track trends in the development of methods for creating a vaccine.
    Keywords:  Bibliometric Analysis; COVID-19/SARS-CoV-2; Vaccine
    DOI:  https://doi.org/10.22074/cellj.2021.7794
  7. Ann Palliat Med. 2021 Nov 17. pii: apm-21-2636. [Epub ahead of print]
       BACKGROUND: Diabetes is an independent risk factor for COVID-19 patients, and SARS-CoV-2 infection may in turn induce hyperglycemia. In this work, we will map the trends of global research of COVID-19 and diabetes by using the method of bibliometric analysis, help researchers quickly understand the research hotspots and find meaningful research directions.
    METHODS: Documents related to COVID-19 and diabetes were obtained from the database of Science Citation Index Expanded of Web of Science. We then analysed the data by country/organization coauthorship analysis, sources/documents citation analysis, and keywords co-occurrence analysis. VOSviewer was applied to map the global research trends and hotspots in this field.
    RESULTS: A total of 1,206 articles were retrieved, including a total of 101 countries, 2,595 organizations, 526 journals, and 3,405 keywords. China had the highest total citations, followed by the United States, while these two countries were reversed in terms of the number of documents. Half of the top 10 highly cited organizations were from China, including Capital Medical University, which had the highest citations, and Huazhong University of Science and Technology, which had the largest number of documents. Diabetes Research and Clinical Practice was the most productive journal. Journal of Medical Virology was the most highly cited journal. Zhou et al.'s article (The Lancet, 2020) was the most representative and widely cited. The keywords mainly focused on 3 categories, namely risk factors & clinical outcomes, receptor ACE2 & cytokine storm, as well as clinical characteristics & epidemiology. Among them, hyperglycemia, obesity, outcomes, and cytokine storm are the hotspots of recent concern.
    CONCLUSIONS: This research mapped the global research trends in COVID-19 and diabetes, which may help researchers identify relevant collaborators and discover current hotspots and potential research directions.
    Keywords:  COVID-19; SARS-CoV-2; VOSviewer; bibliometrics; diabetes
    DOI:  https://doi.org/10.21037/apm-21-2636
  8. BMC Musculoskelet Disord. 2021 Nov 22. 22(1): 968
       OBJECTIVES: The present study aimed to evaluate the status and trends of robotic orthopedic surgery in a clinical setting using bibliometrics.
    METHODS: All relevant publications on the clinical use of robotic surgery in orthopedics were searched from the Web of Science database. Subsequently, data were analyzed using bibliometrics. Visualizing data of bibliographic coupling, co-citation, and co-occurrence analysis were performed using VOSviewer.
    RESULTS: In total, 224 clinical studies met the included standards between 2000 to 2019. Global publications presented an increasing annual trend, with the United States found to have the largest number of publications and robotic companies active in the field (n = 99), followed by China (n = 38), and the United Kingdom (n = 27). The institution with the most contributions was the Beijing Jishuitan Hospital in China (n = 15). The most productive scholars were Tian Wei and Mont Michael A, with 14 publications each. The top 30 most cited papers list showed 29 publications to be cited on more than 40 occassions. The journal with the most related and influential publications on robotic orthopedic surgery was the Journal of Arthroplasty. Fourteen types of robots were used, with the majority applied in knee and spinal surgery. MAKO was the most widely used robot in hip and knee surgery and Mazor in spinal surgery. Most studies were small sample populations of low-quality in this field. The top 20 most frequently used keywords were identified from 950 author keywords. Research on orthopedic robots were classified into two clusters by co-occurrence networks: spinal-related robotic surgery and joint-related robotic surgery.
    CONCLUSIONS: The present bibliometric study summarizes the clinical research of orthopedic robots on study type, sample size, type of surgery, robot information, surgical site, most popular keywords, most cited papers, journals, authors, institutions, and countries. These findings may assist the scholars better understand the current status and research trends to guide future practice and directions.
    Keywords:  Bibliometrics; Orthopedics; Research; Robotic surgical procedures
    DOI:  https://doi.org/10.1186/s12891-021-04714-7
  9. Arq Neuropsiquiatr. 2021 Nov;pii: S0004-282X2021001101002. [Epub ahead of print]79(11): 1002-1011
       BACKGROUND: Scientific productivity on motor neuron disease (MND) research has been hypothesized to be low in Southeast Asia (SEA).
    OBJECTIVE: To investigate the scientific productivity of SEA countries on MND and the associations between research metric indices and various country-specific socioeconomic parameters.
    METHODS: We searched electronic databases for relevant articles from SEA on MND from the earliest indexed record to June 30, 2020. We obtained the following research productivity indices: bibliometric (number of publications in journals with impact factor (IF) and Scopus citations) and altmetric indices (PlumX metrics). We also collected data from published literature and reliable sources on the following socioeconomic variables: population, gross domestic product (GDP), GDP per capita, %GDP allocated for research and development (R&D) and the number of neurologists per country.
    RESULTS: We included 196 articles that satisfied our inclusion criteria. Amyotrophic lateral sclerosis studies comprised the majority of the articles (n = 112; 57.1%). The top three countries in terms of the numbers of publications in journals with IF and in PlumX metrics were Singapore (n = 129), Malaysia (n = 26), and Thailand (n = 18). GDP per capita, %GDP for R&D and number of neurologists per one million population had strong positive correlations with the bibliometric and altmetric indices.
    CONCLUSIONS: This study highlights that although the scientific productivity of MND research in SEA has been low, it is continuously growing. This also emphasizes the imperative to improve economic indices and the number of neurologists in SEA to enhance scientific output on MND.
    DOI:  https://doi.org/10.1590/0004-282X-ANP-2019-0464
  10. Heliyon. 2021 Nov;7(11): e08258
       Introduction: COVID-19 is a disease with worldwide impact that has fully caught attention of researchers. The Cuban scientific output, after one year of confronting this pandemic, has not been studied from a bibliometric perspective.
    Objective: To characterize the output of original scientific articles and review articles on COVID-19 published by Cuban authors in the journals included in the Scopus bibliographic database, the collaborations in these publications and their impact, according to the citation of the research in the world literature.
    Materials and methods: A cross-sectional, descriptive and observational study was performed, using a bibliometric approach. A search strategy was used to retrieve articles on the subject and bibliometric indicators of output, visibility, leadership, collaboration and impact were studied.
    Results: Cuba contributed 2.5% of the Latin American output and 0.2% of the world output. Of the national scientific output (133 articles, 111 original and 22 reviews), 84.2% were authored by a Cuban corresponding author (Cuban leadership). However, the majority (n = 20; 71.4%) of articles with international collaboration (n = 28; 21.1%) had foreign corresponding authors. Of the total, 33.8% (n = 45) corresponded to articles without collaboration. Only 13.5% of the articles (n = 18) were published in journals with high visibility (Q1). Of all the output, 68.4% (n = 91) was in Cuban journals. The output in English represented 29.3% (n = 39) and achieved greater impact than the articles in Spanish in terms of citations. As the visibility of the journals increased according to the quartiles where they are, the percentage of articles published in English and cited articles increased too, but Cuban scientific leadership decreased.
    Conclusions: The greater the leadership in Cuban research, the lower its impact, and the lower the indexes of international collaboration. Cuban researchers are not yet able to systematically generate research that has a significant impact on the international scientific community.
    Keywords:  Bibliometrics; COVID-19; Cuba; SARS-CoV-2; Scientometrics
    DOI:  https://doi.org/10.1016/j.heliyon.2021.e08258
  11. Minerva Med. 2021 Oct;112(5): 631-640
       INTRODUCTION: There was significant surge in the academic publications after the onset of COVID-19 outbreak. The aim of this study was to scientometrically analyze all the medical publications on COVID-19 in 2020 as well as the top 100 cited articles.
    EVIDENCE ACQUISITION: We performed a search of the "Web of Science" database using the keywords "COVID," and "corona" on December 20, 2020.
    EVIDENCE SYNTHESIS: Our search retrieved a total of 45,420 articles on the topic COVID-19 in the year 2020. Corresponding authors from 143 countries contributed to these articles. The highest number of articles were contributed by corresponding authors from the USA (N.=10299), whereas 50 articles in the top 100 cited articles had corresponding authors from China. Among the top 100 cited, the majority were published from Huazhong University of Science and Technology in China (N.=37). New England Journal of Medicine had the maximum impact (h-index of 57), closely followed by Lancet (h-index=55).
    CONCLUSIONS: Scientific publications amount on COVID-19 disease grew at an astonishing pace during 2020. We caution the readers that this rapidity of publication could have missed out on the rigorous review process and the scientific basis of the methods followed.
    DOI:  https://doi.org/10.23736/S0026-4806.21.07489-9
  12. IEEE Access. 2020 ;8 133377-133402
      Corona pandemic has affected the whole world, and it is a highly researched area in biological sciences. As the current pandemic has affected countries socially and economically, the purpose of this bibliometric analysis is to provide a holistic review of the corona pandemic in the field of social sciences. This study aims to highlight significant, influential aspects, research streams, and themes. We have reviewed 395 journal articles related to coronavirus in the field of social sciences from 2003 to 2020. We have deployed 'biblioshiny' a web-interface of the 'bibliometrix 3.0' package of R-studio to conduct bibliometric analysis and visualization. In the field of social sciences, we have reported influential aspects of coronavirus literature. We have found that the 'Morbidity and Mortality Weekly Report' is the top journal. The core article of coronavirus literature is 'Guidelines for preventing health-care-associated pneumonia'. The most commonly used word, in titles, abstracts, author's keywords, and keywords plus, is 'SARS'. Top affiliation is 'The University of Hong Kong'. Hong Kong is a leading country based on citations, and the USA is on top based on total publications. We have used a conceptual framework to identify potential research streams and themes in coronavirus literature. Four research streams are found by deploying a co-occurrence network. These research streams are 'Social and economic effects of epidemic disease', 'Infectious disease calamities and control', 'Outbreak of COVID 19,' and 'Infectious diseases and the role of international organizations'. Finally, a thematic map is used to provide a holistic understanding by dividing significant themes into basic or transversal, emerging or declining, motor, highly developed, but isolated themes. These themes and subthemes have proposed future directions and critical areas of research.
    Keywords:  Bibliometric analysis; COVID survey; COVID-19; SARS; biblioshiny; conceptual structure; coronavirus; pandemic; r-studio; social sciences
    DOI:  https://doi.org/10.1109/ACCESS.2020.3008733
  13. Clin Exp Optom. 2021 Nov 23. 1-6
       CLINICAL RELEVANCE: Publications in refereed scientific journals provide a rigorous research base that underpins clinical optometric practice. Leading optometrists who generate this literature can be identified and ranked using standardised citation indicators.
    BACKGROUND: This work seeks to identify and rank all optometrists included in a Science-Wide author database of standardised citation indicators (S-W) and to compare this ranking with the Global Optometrist Top 200 Research Ranking (T200).
    METHODS: A search was conducted for the names of all optometrists in the T200 who were included in the S-W, which is a world-wide listing of the top 2% of scientists in each of 174 subfield disciplines, ranked according to a composite citation indicator (cns) that excludes self-citations and corrects for multiple authorships and author order.
    RESULTS: The names of 66 optometrists are found in the S-W. Of these, 58 are designated as working in the primary sub-field 'Ophthalmology & Optometry'; this listing, in rank-order of cns, is referred to as the 'S-W-derived Optometrist Research Ranking' (S-WORR). Australian optometrist Nathan Efron is ranked #1 in the S-WORR. The number (%) of optometrists in the S-WORR from each country is: the United States - 26 (45%), Australia - 12 (21%), the United Kingdom - 11 (19%), Canada - 5 (9%), Spain - 2 (3%), Hong Kong - 1 (2%) and South Africa - 1 (2%). The universities housing the equal highest number of optometrists in the S-WORR (five each) are the University of California, Berkeley, USA; the University of New South Wales, Australia; and Queensland University of Technology, Australia. There is a moderately strong correlation between T200 and S-WORR rankings (ρ = 0.6017, N = 58, p < 0.0001).
    CONCLUSIONS: The S-WORR represents an elite cohort of optometrists who ought to be celebrated for their outstanding, leading and impactful contributions to optometric research.
    Keywords:  Citations; global optometrist research ranking; h-index; publication metrics; science-wide author database; standardised citation indicators
    DOI:  https://doi.org/10.1080/08164622.2021.1981744
  14. J Adv Nurs. 2021 Nov 23.
       AIM: The present study aims to explore the research hot spots, development trends and knowledge structure of dignity in the nursing field.
    DESIGN: Quantitative and co-word biclustering analysis were used.
    METHODS: Articles on dignity care published from 01 Jan 2011 to 31 Dec 2020, were retrieved from PubMed. The extracted Medical Subject Headings (MeSH) terms were quantitatively analysed using Bibliographic Item Co-occurrence Matrix Builder software. To determine the hot spots, a biclustering analysis was completed using gCluto1.0 software. A strategic diagram and a social network analysis (SNA) were used to reveal trends in the theme and knowledge structure.
    RESULTS: In the parameters of the retrieval strategy, a total of 1977 papers were included in the present study. Amongst all the extracted MeSH terms, 27 high-frequency MeSH terms were identified, and the hot spots were grouped into five categories. These were namely dignity in: (1) dementia care, (2) palliative care, (3) older people care, (4) healthcare and (5) clinical nursing. In the strategic diagram, the study of dignity in clinical nursing was active and should become an emerging field of research in the near future.
    CONCLUSIONS: Based on the co-word biclustering of dignity care over the past 10 years, five hot spots were identified, and it was predicted that research on dignity in clinical nursing would be the main trend in future studies. Amongst the five themes it was interesting to note that dignity in dementia and palliative care are core priorities to which scholars should pay more attention.
    IMPACT: In recent years, dignity-conserving care has been highly valued, however, there are few relevant bibliometric articles that can be referenced on this topic. The present study was considered to offer novel insights into research on dignity in nursing and could be a reliable reference point for researchers when launching new projects.
    Keywords:  bibliometric analysis; biclustering; co-word analysis; dignity; hot spots; nursing; social network analysis
    DOI:  https://doi.org/10.1111/jan.15097
  15. Healthcare (Basel). 2021 Nov 08. pii: 1520. [Epub ahead of print]9(11):
      Healthcare decision-makers increasingly face a changing and ever-evolving landscape, forcing them to formulate public policies based on the results from different scientific investigations. This article evaluates the field of research on patient satisfaction as a basis for health policies. The analysis was carried out with a sample of 621 articles published between 2000 and 2020 in the Scopus database. The world's largest producer and research co-operator on patient satisfaction and health policy was the United States. However, the most prolific authors, institutions, and journals are of British origin. Regarding the themes, we find that, in economic and management matters, scientific production is scarce. To study the evolution of keywords, we divided the study period into two periods of an equal number of years. In both sub-periods, the keyword "Human" stands out. In the second sub-period, the word "Perception" stands out, which indicates the current attention paid to the patient's opinion.
    Keywords:  Scopus; bibliometric analysis; health policy; health system; patient satisfaction; research trends
    DOI:  https://doi.org/10.3390/healthcare9111520
  16. Invest Educ Enferm. 2021 Oct;39(3):
       OBJECTIVES: To analyze levels of production, reach, and thematic development of the Investigación y Educación en Enfermería journal from a scientometric analysis.
    METHODS: The study collected 1,066 articles corresponding to the period between 1983 and 2020. The scientometric analysis was carried out from three components of descriptive analysis: performance of the publication, geographic reach, and thematic development. The first two used data consolidated from articles published in the Open Journal System at Universidad de Antioquia. The third component captured the bibliographic references from the Web of Science and Scopus databases and from the Google Scholar and Lens academic search engines.
    RESULTS: In terms of the production analysis, the Journal shows stable behavior sustained over time with international reach regarding authorship. In the thematic setting, the Journal concentrates on two large clusters: 1) research on human factors from different perspectives and 2) cross-sectional studies differentiated mainly by sex. With respect to emerging clusters, on one side, a thematic pillar is seen with studies in young adult population and another in matters related to the educational process and nursing students.
    CONCLUSIONS: The Journal has maintained outstanding behavior in terms of production over time, aligned with very good visibility for potential authors internationally; something not easily accomplished for most journals in Colombia. Likewise, its production has had a thematic domain to a greater extent related to human factors associated with the nursing practice.
    Keywords:  bibliometrics; scientific publication indicators; serial publications
    DOI:  https://doi.org/10.17533/udea.iee.v39n3e02
  17. Plants (Basel). 2021 Nov 01. pii: 2358. [Epub ahead of print]10(11):
      Phycobiliproteins are gaining popularity as long-term, high-value natural products which can be alternatives to synthetic products. This study analyzed research trends of phycobiliproteins from 1909 to 2020 using a bibliometric approach based on the Scopus database. The current findings showed that phycobiliprotein is a burgeoning field in terms of publications outputs with "biochemistry, genetics, and molecular biology" as the most related and focused subject. The Journal of Applied Phycology was the most productive journal in publishing articles on phycobiliproteins. Although the United States of America (U.S.A.) contributed the most publications on phycobiliproteins, the Chinese Academy of Sciences (China) is the institution with the largest number of publications. The most productive author on phycobiliproteins was Glazer, Alexander N. (U.S.A.). The U.S.A. and Germany were at the forefront of international collaboration in this field. According to the keyword analysis, the most explored theme was the optimization of microalgae culture parameters and phycobiliproteins extraction methods. The bioactivity properties and extraction of phycobiliproteins were identified as future research priorities. Synechococcus and Arthrospira were the most cited genera. This study serves as an initial step in fortifying the phycobiliproteins market, which is expected to exponentially expand in the future. Moreover, further research and global collaboration are necessary to commercialize phycobiliproteins and increase the consumer acceptability of the pigments and their products.
    Keywords:  CiteSpace; R studio; Scopus database; applications; bioproduction; biotechnology; commercial; microalgae; pigment
    DOI:  https://doi.org/10.3390/plants10112358
  18. Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Jun 10. 42(6): 1128-1132
      Objective: In recent years, the editorial board and editorial department of Chinese Journal of Epidemiology have taken a series of measures to further improve the academic quality and influence of the journal. This study analyzed the citation index of Chinese Journal of Epidemiology from 2006 to 2019, and evaluated the academic quality and influence of the journal. Methods: The total citation frequency, impact factor, annual index and other citation rate etc. of Chinese Journal of Epidemiology were extracted from Chinese S&T Journal Citation Report, 2006-2019 (Expanded Edition) and Chinese S&T Journal Citation Report, 2006-2019 (Natural Science) for the analysis on academic quality and influence of the journal. Results: From 2006 to 2019, there were 241-406 articles published in Chinese Journal of Epidemiology per year. The literature selection rate over the years ranged from 66% to 100%. The total expanded citation frequency of Chinese Journal of Epidemiology increased from 3 365 in 2006 to 7 817 in 2019, and the total core citation frequency increased from 1 875 in 2006 to 5 055 in 2019 with slight fluctuation. The expanded impact factor increased from 1.566 in 2006 to 2.799 in 2019. The core impact factor increased from 0.904 in 2006 to 1.842 in 2019. The expanded annual index rose from 0.224 in 2006 to 0.741 in 2019. The core annual index rose from 0.170 in 2006 to 0.602 in 2019. Conclusion: The academic quality and influence of Chinese Journal of Epidemiology has been improved gradually and its ability to focus on hot spots and report new academic achievement has been further strengthened in recent years.
    DOI:  https://doi.org/10.3760/cma.j.cn112338-20210519-00410
  19. Acta Chir Plast. 2021 ;63(3): 127-138
       BACKGROUND: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a recently discovered malignancy of T-cell type, correlated with the use of silicone breast implants. It has been theorized that the etiology may be linked to bacterial growth and long-term inflammation. The afflicted patient usually presents with breast swelling due to peri-implant fluid accumulation. Currently, the diagnosis is achieved by ultrasound, biopsy and testing for certain biomarkers. Following this, the treatment is achieved by complete surgical excision, or by capsulectomy and exchange with smoother surfaced implants. The aim of this study was to identify and report 50 most cited articles related to the field of BIA--ALCL.
    METHODS: The Web of Science Citation Index was used to identify 325 articles pertaining to BIA-ALCL. The 50 most cited articles among these were included in this study. The title, author name, journal and year of publication, country and institute of origin, level of evidence (LoE), type of study (clinical or basic), and topic of study (pathophysiology, oncologic management, diagnosis, case report and case series) were recorded.
    RESULTS: This study includes articles from the period 1997-2018 with an average citation rate of 65.5. The majority of the top cited articles (36%; N = 18) were found to be case reports, followed by case series (18%; N = 9), systemic reviews (12%; N = 6) and studies focused on the pathophysiology (16%; N = 8), oncologic management (6%; N = 3), databases (6%; N = 3), diagnostics (4%; N = 2) and informed consent (2%; N = 1). The articles were published across 30 journals and originated from 35 institutes. The United States was found to be the country of origin of most of the studies. While none of the articles achieved LoE 1, many were found to have LoE 4 (N = 11) or 5 (N = 19). Most of the articles (N = 42), were clinical research studies.
    CONCLUSION: According to this citation analysis, a large fraction of the existing high impact literature on BIA-ALCL is focused on disease monitoring. Through this study, we hope to present a simple educational tool to better appreciate the research in this relatively young field.
    Keywords:  BIA-ALCL; breast implant illness; breast implant lymphoma; breast implant-associated anaplastic large cell lymphoma
    DOI:  https://doi.org/10.48095/ccachp2021127
  20. Int J Nurs Pract. 2021 Nov 21. e13027
       AIM: This study aimed to investigate the characteristics of global productivity of nursing research in subspecialty nursing journals and to provide a general view of global nursing research.
    METHODS: On 10 January 2020, Web of Science was used for research collection. Publications in subspecialty nursing journals from 2015 to 2019 were analysed.
    RESULTS: A total of 34 275 publications were retrieved. The United States (15 155) ranked first, followed by Australia (2439), China (2076), Brazil (1803) and the United Kingdom (1602). High-income economies produced 82.26% of the total number of publications. Research production was not significantly correlated with the population (p = 0.113, r = 0.412), whereas it was positively correlated with gross domestic product (p = 0.030, r = 0.541). The United States had the highest number of total citations (46 297). The Netherlands ranked highest when analysing mean citations, followed by Finland and Australia. Sweden ranked highest after correcting for gross domestic product, followed by Australia and Finland. Australia was the most productive nation when adjusted by population, followed by Sweden and Norway.
    CONCLUSION: The United States is the leader in nursing research productivity. Countries with large economies tend to make greater contributions to global nursing research. Some European countries and Australia were found to be more prolific when stratified by population size and economic activity.
    Keywords:  gross domestic product; journal; nursing; publication
    DOI:  https://doi.org/10.1111/ijn.13027
  21. Mar Drugs. 2021 Oct 26. pii: 606. [Epub ahead of print]19(11):
      Fucoxanthin is a major carotenoid in brown macroalgae and diatoms that possesses a broad spectrum of health benefits. This review evaluated the research trends of the fucoxanthin field from 1928 to June 2021 using the bibliometric method. The present findings unraveled that the fucoxanthin field has grown quickly in recent years with a total of 2080 publications. Japan was the most active country in producing fucoxanthin publications. Three Japan institutes were listed in the top ten productive institutions, with Hokkaido University being the most prominent institutional contributor in publishing fucoxanthin articles. The most relevant subject area on fucoxanthin was the agricultural and biological sciences category, while most fucoxanthin articles were published in Marine Drugs. A total of four research concepts emerged based on the bibliometric keywords analysis: "bioactivities", "photosynthesis", "optimization of process'', and "environment". The "bioactivities" of fucoxanthin was identified as the priority in future research. The current analysis highlighted the importance of collaboration and suggested that global collaboration could be the key to valorizing and efficiently boosting the consumer acceptability of fucoxanthin. The present bibliometric analysis offers valuable insights into the research trends of fucoxanthin to construct a better future development of this treasurable carotenoid.
    Keywords:  Scopus; applications; bibliometric; biosynthesis; carotenoids; fucoxanthin; health benefits; macroalgae; microalgae; production
    DOI:  https://doi.org/10.3390/md19110606
  22. Arch Plast Surg. 2021 Nov;48(6): 651-659
       BACKGROUND: Many surgical specialties have had pioneering influences from plastic surgeons. However, many of these areas of practice have evolved to include surgeons from diverse training backgrounds. This raises the question as to whether the prominence of other specialties in clinical practice translates to greater research productivity in these areas. The objective of this paper is to investigate the publication volumes of plastic surgeons in selected areas of practice compared to surgeons from other disciplines.
    METHODS: PubMed was used to examine publication trends in areas associated with plastic surgery. Searches for the following topics were performed: head and neck reconstruction, hand surgery, breast reconstruction, ventral hernia repair, abdominal component separation, brachial plexus injury, craniofacial surgery, and aesthetic surgery. Affiliation tags were used to examine contributions from nine specialties. Web of Science was used to identify the top cited articles for the last 10 years in each area.
    RESULTS: Articles by non-plastic surgeons comprise the majority of the literature for all areas of practice studied except for breast reconstruction and aesthetic surgery. Despite this, plastic surgeons contributed the greatest number of top cited articles over the last 10 years for five of the areas of practice.
    CONCLUSIONS: While plastic surgeons do not contribute the greatest proportion of articles published each year in several of the selected areas of practice, they do publish a larger number of articles that are the most cited. Plastic surgeons remain the dominant academic force in terms of volume and citations for both breast and aesthetic surgery.
    Keywords:  Mammaplasty; PubMed; Surgery, plastic
    DOI:  https://doi.org/10.5999/aps.2021.00745
  23. Autophagy. 2021 Nov 23. 1-14
      After its discovery in the 1950 s, the autophagy research field has seen its annual number of publications climb from tens to thousands. The ever-growing number of autophagy publications is a wealth of information but presents a challenge to researchers, especially those new to the field, who are looking for a general overview of the field to, for example, determine current topics of the field or formulate new hypotheses. Here, we employed text mining tools to extract research trends in the autophagy field, including those of genes, terms, and topics. The publication trend of the field can be separated into three phases. The exponential rise in publication number began in the last phase and is most likely spurred by a series of highly cited research papers published in previous phases. The exponential increase in papers has resulted in a larger variety of research topics, with the majority involving those that are directly physiologically relevant, such as disease and modulating autophagy. Our findings provide researchers a summary of the history of the autophagy research field and perhaps hints of what is to come.Abbreviations: 5Y-IF: 5-year impact factor; AIS: article influence score; EM: electron microscopy; HGNC: HUGO gene nomenclature committee; LDA: latent Dirichlet allocation; MeSH: medical subject headings; ncRNA: non-coding RNA.
    Keywords:  Autophagy; text analysis; text analytics; text mining; topic modeling
    DOI:  https://doi.org/10.1080/15548627.2021.1995151
  24. Tour Manag Perspect. 2021 Oct;40 100912
      By adopting a bibliometric analysis approach, this study systematically reviews and retrospectively analyses the rapidly emerging literature on COVID-19 in tourism and hospitality. A co-word analysis revealed the intellectual structure of 177 papers (published until January 2021) consisting of four major themes discussing the following various issues: 1) the impact of COVID-19 on tourist decision-making, destination marketing, technology adoption, and tourists' well-being; 2) the future of tourism post COVID-19; 3) managing change in tourism; and 4) the COVID-19's impacts on tourism and hospitality stakeholders. The findings show that preliminary publications tend to be descriptive, pre-mature and theoretical, i.e. most studies advocate and re-imagine a more sustainable, responsible and equitable post-pandemic tourism, but almost no research investigates in-depth whether, why and how such theoretical proclamations are being materialized or not and/or whether they will remain a COVID-19 induced fuss. The paper concludes by offering various directions and propositions for future research.
    Keywords:  Bibliometric analysis; COVID-19; Crisis; Hospitality; Pandemic; Reflective review; Research themes; Tourism
    DOI:  https://doi.org/10.1016/j.tmp.2021.100912
  25. Front Psychiatry. 2021 ;12 722240
      Background: This study aimed to identify frontiers for further studies via brief understanding in complementary and alternative medicine (CAM) for substance use disorders (SUDs). Materials and Methods: Publications on the use of CAM for treating SUDs were retrieved from the Web of Science Core Collection from 2001 to 2020 on July 12, 2020, and visualized by CiteSpace V. Results: A total of 3,807 publications were obtained. The USA, China, and England were the leading research centers. However, India and Pakistan have recently focused on assessing CAM for the treatment of SUDs. Frederick L Altice was found to be the most productive author. Addiction ranked first among the frequently cited journals, which exceeded 1,000. The most common CAM therapies were acupuncture and CAM psychotherapies, such as mindfulness meditation. Conclusion: CAM is gaining attention globally for treating SUDs. CAM psychotherapy and acupuncture are hotspots and deserve further study. Researchers should strengthen peer cooperation in this field.
    Keywords:  acupuncture; bibliometrics [MeSH]; complementary therapies; science map; substance-related disorders
    DOI:  https://doi.org/10.3389/fpsyt.2021.722240
  26. Environ Dev Sustain. 2021 Nov 14. 1-18
      Mangrove land use changes of varied intensities have long been a problem in tropical mangrove forests. This has resulted in various degrees of mangrove land use modification, which catch many interests in the region for research. The research provided here is a bibliometric analysis of scholarly articles published around the world in various publication document types on changes in land use of tropical mangrove forests based on remote sensing and Geographical Information System (GIS). Scientific data analysis was undertaken by using bibliometric approaches on 6,574 papers extracted from the Scopus databases between 2010 and 2020. The findings revealed that the number of publications continuously climbed from under 400 to an average of 50-60 per year till 2019. The data showed that the mangrove forest modifications study gained traction when the highest number of citations, 9,236 in 2015, were observed. We can also notice that the overall number of citations fluctuated a lot during the first five years (2010-2015) but increased from 2013 to 2015. The findings demonstrate how remote sensing satellites have aided vegetation and land study in recent years. The findings also revealed that the analysis tools of Land Use Change, Vegetation Index, Mangrove, Tropical Country, Remote Sensing, and Tropical contributed to scientific knowledge of current issues of mangrove land use change in the tropical region. The authors' keywords, Remote Sensing in particular, supplied roughly 43%, Normalized Difference Vegetation Index (13%), Vegetation Index (9%), and other keywords contributed less than 7%. The growth pattern of the keywords "MODIS" and "Landsat" implies that both will stay important over the next five years, according to an analysis of the type of satellite used in land use assessment. Meanwhile, papers pertaining to policy on land use change, food security, and forest resources were evaluated in order to highlight policy and academic research findings on the topics. The application of the Normalized Difference Vegetation Index, which is a very relevant tool that can be used in monitoring land use changes and assessing vegetation status because it is a desirable technique in measuring plant health and vigour, can help fill the research gaps presented in this study. This review can help with the development of better mangrove land use change approaches in tropical mangroves and around the world using satellite remote sensing and GIS.
    Keywords:  Land use change; MODIS; Malaysia; Mangrove
    DOI:  https://doi.org/10.1007/s10668-021-01935-7
  27. Ther Innov Regul Sci. 2021 Nov 22.
      Horizon scanning for innovative technologies that might be applied to medical products and requires new assessment approaches to prepare regulators, allowing earlier access to the product for patients and an improved benefit/risk ratio. The purpose of this study is to confirm that citation network analysis and text mining for bibliographic information analysis can be used for horizon scanning of the rapidly developing field of AI-based medical technologies and extract the latest research trend information from the field. We classified 119,553 publications obtained from SCI constructed with the keywords "conventional," "machine-learning," or "deep-learning" and grouped them into 36 clusters, which demonstrated the academic landscape of AI applications. We also confirmed that one or two close clusters included the key articles on AI-based medical image analysis, suggesting that clusters specific to the technology were appropriately formed. Significant research progress could be detected as a quick increase in constituent papers and the number of citations of hub papers in the cluster. Then we tracked recent research trends by re-analyzing "young" clusters based on the average publication year of the constituent papers of each cluster. The latest topics in AI-based medical technologies include electrocardiograms and electroencephalograms (ECG/EEG), human activity recognition, natural language processing of clinical records, and drug discovery. We could detect rapid increase in research activity of AI-based ECG/EEG a few years prior to the issuance of the draft guidance by US-FDA. Our study showed that a citation network analysis and text mining of scientific papers can be a useful objective tool for horizon scanning of rapidly developing AI-based medical technologies.
    Keywords:  Artificial intelligence; Citation network; Delivery of health care/trends; Diagnostic imaging; Horizon scanning
    DOI:  https://doi.org/10.1007/s43441-021-00355-z
  28. Front Public Health. 2021 ;9 764069
      In contemporary "high-risk" society, unexpected disasters (epidemics and extreme weather) and chronic pressures (aging problems) put tremendous pressure on healthcare facilities. Enhancing the healthcare facilities' resilience ability to resist, absorb, and respond to disaster disruptions is urgent. This study presents a scientometric review for healthcare facility resilience research. A total of 374 relevant articles published between 2000 and 2020, collected from Web of Science (WoS) core collection database, Scopus database and MEDLINE database were reviewed and analyzed. The results indicated that research on resilience in healthcare facilities went through three development periods, and the research involved countries or institutions that are relatively scattered. The studies have been focused on the subject categories of engineering, public, environmental, and occupational health. The keywords of "resilience," "hospital," "disaster," "healthcare," and "healthcare facility" had the most frequency. Furthermore, based on the literature co-citation networks and content analysis, the detected seven co-citation clusters were grouped into four knowledge domains: climate change impact, strengthening resilience in response to war and epidemic, resilience assessment of healthcare facility, and the applications of information system. Moreover, the timeline view of literature reflected the evolution of each domain. Finally, a knowledge map for resilience of healthcare facilities was put forward, in which critical research contents, current knowledge gaps, and future research work were discussed. This contribution will promote researchers and practitioners to detect the hot topics, fill the knowledge gaps, and extend the body of research on resilience of healthcare facilities.
    Keywords:  bibliometrics; delivery of health care; disasters; epidemics; healthcare facility; hospitals; knowledge map; resilience
    DOI:  https://doi.org/10.3389/fpubh.2021.764069
  29. J Neurosurg. 2021 Nov 26. pii: 2021.7.JNS211530. [Epub ahead of print] 1-13
       OBJECTIVE: In this study, the authors sought to determine which US medical schools have produced the most neurosurgery residents and to evaluate potential associations between recruitment and medical school characteristics.
    METHODS: Demographic and bibliometric characteristics were collected for 1572 residents in US-based and Accreditation Council for Graduate Medical Education (ACGME)-accredited neurosurgery programs over the 2014 to 2020 match period using publicly available websites. US medical school characteristics were collected, including class size, presence of a home neurosurgery program, number of clinical neurosurgery faculty, research funding, presence of a neurosurgery interest group, and a top 10 ranking via U.S. News & World Report or Doximity. Correlations and associations were then evaluated using Pearson's correlation coefficient (PCC), independent-samples t-test, and univariable or stepwise multivariable linear regression, as appropriate.
    RESULTS: Vanderbilt University produced the most neurosurgery residents as a percentage of medical graduates at 3.799%. Case Western Reserve University produced the greatest absolute number of neurosurgery residents (n = 40). The following factors were shown to be associated with a higher mean percentage of graduates entering neurosurgery: number of clinical neurosurgery faculty (PCC 0.509, p < 0.001), presence of a neurosurgery interest group (1.022% ± 0.737% vs 0.351% ± 0.327%, p < 0.001) or home neurosurgery program (1.169% ± 0.766% vs 0.428% ± 0.327%, p < 0.001), allopathic compared with osteopathic school (0.976% ± 0.719% vs 0.232% ± 0.272%, p < 0.001), U.S. News top 10 ranking for neurology and neurosurgery (1.923% ± 0.924% vs 0.757% ± 0.607%, p < 0.001), Doximity top 10 residency program ranking (1.715% ± 0.803% vs 0.814% ± 0.688%, p < 0.001), and amount of NIH funding (PCC 0.528, p < 0.001).
    CONCLUSIONS: The results of this study have delineated which medical schools produced the most neurosurgery residents currently in training, and the most important independent factors predicting the percentage of graduates entering neurosurgery and the preresidency h-index.
    Keywords:  career choice; education; internship and residency; personnel selection; publishing; research
    DOI:  https://doi.org/10.3171/2021.7.JNS211530
  30. Zool Res. 2022 Jan 18. pii: 2095-8137(2022)01-0001-02. [Epub ahead of print]43(1): 1-2
      With the long-term support of every friend and contributor, Zoological Research ( ZR) has continued to move forward over the past year, with impressive achievements. Notably, ZR attained an impact factor of 4.56 (JCR Q1) and CiteScore of 4.6 in mid-2021, thus ranking in the top five of the 175 SCI journals within the Zoology category. In November 2021, our Citescore reached 5.6, and we expect a higher impact factor in 2022 than in 2021. Although we are not driven by chasing these scores, the increase in these metrics does reflect an elevation in the quality of submissions and publications, as well as the march towards our original aspiration when launching this journal (Yao et al., 2019). The current areas of focus of ZR (i.e., primate and animal models; animal diversity and evolution; conservation & utilization of animal resources) are not only tightly connected to our host - the Kunming Institute of Zoology, which has grown and evolved into " a comprehensive research institution renowned for its remarkable achievements in evolutionary mechanisms of animal biodiversity, animal resources protection, and sustainable utilization" (Yao & Shen, 2019) - but also represent the very frontiers of zoology.
    DOI:  https://doi.org/10.24272/j.issn.2095-8137.2021.410
  31. IEEE Access. 2021 ;9 45001-45016
      As a global pandemic threatens health and livelihoods, finding effective treatments has become a vital issue that requires worldwide collaboration. This study examines research collaboration and network profiles through a case study of coronavirus diseases, including both the extinct severe acute respiratory syndrome coronavirus (SARS-CoV) and the emerging species (SARS-CoV-2). A scientometric process was designed to apply quantitative tools and a qualitative approach employing technological expertise to accomplish a three-level collaboration analysis. The text mining software, VantagePoint, was used to analyze research articles from the Web of Science database to identify the key national, organizational, and individual players in the coronavirus research field combined with indicators, namely, the breadth and depth of collaboration. The results show that China and the United States are at the center of coronavirus research networks at all three levels, including many endeavors involving single or joint entities. This study demonstrates how governments, public sectors, and private sectors, such as the pharmaceutical industry, can use scientometric analysis to gain insight into the holistic research trends and networks of players in this field, leading to the formulation of strategies to strengthen research and development programs. Furthermore, this approach can be utilized as a visualization and decision support tool for further policy planning, identification and execution of collaboration, and research exchange opportunities. This scientometric process should be directly applicable to other fields.
    Keywords:  Bibliometrics; coronavirus; network analysis; research collaboration; scientometrics
    DOI:  https://doi.org/10.1109/ACCESS.2021.3066450
  32. PLoS Biol. 2021 Nov;19(11): e3001133
      Alongside the growing concerns regarding predatory journal growth, other questionable editorial practices have gained visibility recently. Among them, we explored the usefulness of the Percentage of Papers by the Most Prolific author (PPMP) and the Gini index (level of inequality in the distribution of authorship among authors) as tools to identify journals that may show favoritism in accepting articles by specific authors. We examined whether the PPMP, complemented by the Gini index, could be useful for identifying cases of potential editorial bias, using all articles in a sample of 5,468 biomedical journals indexed in the National Library of Medicine. For articles published between 2015 and 2019, the median PPMP was 2.9%, and 5% of journal exhibited a PPMP of 10.6% or more. Among the journals with the highest PPMP or Gini index values, where a few authors were responsible for a disproportionate number of publications, a random sample was manually examined, revealing that the most prolific author was part of the editorial board in 60 cases (61%). The papers by the most prolific authors were more likely to be accepted for publication within 3 weeks of their submission. Results of analysis on a subset of articles, excluding nonresearch articles, were consistent with those of the principal analysis. In most journals, publications are distributed across a large number of authors. Our results reveal a subset of journals where a few authors, often members of the editorial board, were responsible for a disproportionate number of publications. To enhance trust in their practices, journals need to be transparent about their editorial and peer review practices.
    DOI:  https://doi.org/10.1371/journal.pbio.3001133
  33. Arq Neuropsiquiatr. 2021 Nov;pii: S0004-282X2021001100974. [Epub ahead of print]79(11): 974-981
       BACKGROUND: Brazil has a top position regarding scientific production on noninvasive neuromodulation worldwide. Knowledge of scientometric phenomena involving Brazilian researchers who produce science on this theme may aid confidence in Brazilian clinical and research professionals.
    OBJECTIVE: To investigate the scenario of research on the theme of noninvasive neuromodulation in Brazil.
    METHODS: This was a scientometric study for mapping scientific production on this subject involving network phenomena, the professions of researchers, institutional affiliation, main research unit, total number of scientific articles on noninvasive neuromodulation published in journals, research sub-area and year of obtaining the PhD title. Public data from Lattes Platform curricula vitae and from VOSViewer© were used.
    RESULTS: A total of 54 Brazilian researchers were identified, of whom 16 are research productivity fellows. Most of them are linked to institutions in southeastern Brazil, involving the professions of biology, biochemistry, physical education, physiotherapy, speech therapy, gerontology, medicine and psychology, with 1175 articles published in journals. These studies involve experimental animal and human models to account for mechanisms, observational studies, case reports, randomized clinical trials, systematic reviews, meta-analyses, product and process development, computer modeling and guidelines.
    CONCLUSIONS: Brazil occupies a prominent place in the world scenario of research on noninvasive neuromodulation, which is used by different professions for treatment of brain dysfunctions, with a trend towards expansion to other fields.
    DOI:  https://doi.org/10.1590/0004-282X-ANP-2020-0480
  34. Otol Neurotol. 2021 Nov 19.
       OBJECTIVE: To establish the level of evidence and publishing trends in otology-specific journals over a 20-year period.
    DESIGN: Retrospective analysis.
    METHODS: The three O/N specific journals with the highest Eigenfactor scores were identified. All articles published in the years 1998, 2008, and 2018 were reviewed and level of evidence (LoE) based on standards set by the Oxford Centres for Evidence Based Medicine was assigned by two independent reviewers. One way analysis of variance and 95% bootstrap sensitivity analysis were performed.
    RESULTS: A total of 1,062 studies were published over 20 years, of these 809 (76.2%) were eligible for inclusion in the present study. The average number of publications per year increased over time. The average LoE improved significantly over the total interval (-0.235, p = 0.027, [CI -0.45, -0.019]), however did not between 1998 and 2008 (p = 0.111) or between 2008 and 2018 (p = 1). When looking at just LoE 1 or 2, the number and percentage of higher quality papers improves over time-48/158 (30.4%) in 1998, rising to 94/250 (37.6%) in 2008, and 158/401 (39.4%) in 2008.
    CONCLUSIONS: Over the past two decades there has been an overall increase in the quantity and quality (as measured by LoE) of publications in O/N-specific journals. In general, quality of O/N studies is slightly better in O/N-specific journals compared with general OHNS journals. However, there are still improvements to be had in the proportion of high-evidence publications, as they still number less than half of all total publications in the subspecialty.
    DOI:  https://doi.org/10.1097/MAO.0000000000003425
  35. Ther Innov Regul Sci. 2021 Nov 22.
      Certain innovative technologies applied to medical product development require novel evaluation approaches and/or regulations. Horizon scanning for such technologies will help regulators prepare, allowing earlier access to the product for patients and an improved benefit/risk ratio. This study investigates whether citation network analysis and text mining of scientific papers could be a tool for horizon scanning in the field of immunology, which has developed over a long period, and attempts to grasp the latest research trends. As the result of the analysis, the academic landscape of the immunology field was identified by classifying 90,450 papers (obtained from PubMED) containing the keyword "immune* and t lymph*" into 38 clusters. The clustering was indicative of the research landscape of the immunology field. To confirm this, immune checkpoint inhibitors were used as a retrospective test topic of therapeutics with new mechanisms of action. Retrospective clustering around immune checkpoint inhibitors was found, supporting this approach. The analysis of the research trends over the last 3 to 5 years in this field revealed several candidate topics, including ARID1A gene mutation, CD300e, and tissue resident memory T cells, which shows notable progress and should be monitored for future possible product development. Our results have demonstrated the possibility that citation network analysis and text mining of scientific papers can be a useful objective tool for horizon scanning of life science fields such as immunology.
    Keywords:  Citation network; Drug development; Horizon scanning; Immune; Immune checkpoint inhibitor; T cell; Text mining
    DOI:  https://doi.org/10.1007/s43441-021-00351-3
  36. Front Res Metr Anal. 2021 ;6 727228
      Background: The challenge of research funding constraints has brought to bear enormous pressure on researchers. Research productivity is relevant to prestige and career progression of academic staff. However, this study aimed to explore significant challenges associated with researchers' productivity and the impact of non-funding of research in Nigerian research and tertiary institutions. Methods: This study adopted a qualitative exploratory design involving academics at various research and tertiary institutions across the six geographical regions in Nigeria. A semi-structured questionnaire was distributed electronically to all participants who consented to take part in this study. Exactly 4,159 questionnaires were administered and 2,350 were completely filled and returned. Pearson correlation matrices with logistic regression were used for data analysis and are presented in frequencies and percentages. Results: On challenges faced by respondents, 42.98% reported a lack of research funding, 17.11% mentioned brain drain challenge while 8.85% indicated a lack of motivation. Of the 23,927 publications reported, the number of those in sciences, engineering, and medical sciences averaged 9.6, 11.5, and 9.5 respectively. The average number of publications by women (10.8) was more than by men (9.7). Lecturers had the highest average research publication number (11.8) followed by researchers (10.2) and others (3.9). Men had the highest (11.9) average number of conferences compared to women (9.2). Participants in engineering had an average number of 13.8 conferences per respondents followed by those in education (11.2), sciences (11.1), and 10.9 for those in agricultural sciences. The result revealed a negative significant correlation between research publication and academic qualification at p < 0.01. Positive significant correlation was observed between research productivity and discipline at p < 0.05. Findings show that the combined influence of the independent variables on research productivity was significant using linear regression analysis. Conclusions: The failure to prioritize research has resulted in underdevelopment in Nigeria. It is therefore imperative that the federal government prioritize research and establish a functional Special Research Trust Fund to oversee research funding in Nigeria.
    Keywords:  academic staff; career progression; challenges; productivity; publication; research policy; researchers
    DOI:  https://doi.org/10.3389/frma.2021.727228
  37. Membranes (Basel). 2021 Oct 24. pii: 808. [Epub ahead of print]11(11):
      The following review aims at analyzing the contribution of Spanish researchers to membrane science and technology, with a historical compilation of the main milestones. We used a bibliometric analysis based on the Scopus database (1960-2020) dealing with 8707 documents covering the different disciplines and subject areas where membranes are involved. Furthermore, the information has been updated to the present moment of writing this manuscript in order to include the latest research lines and the different research groups currently active in Spain, which may lead the way to the development of the field in the coming years.
    Keywords:  Spanish research groups; bibliometric analysis; membrane processes; membrane technology
    DOI:  https://doi.org/10.3390/membranes11110808
  38. Plast Reconstr Surg Glob Open. 2021 Nov;9(11): e3897
       Background: Breast reconstruction is an important aspect in breast cancer treatment.
    Methods: A comprehensive search of MEDLINE, Embase, and the Cochrane Library of Systematic Reviews was performed. Systematic reviews and meta-analyses that focused on breast reconstruction and were published between 2000 and 2020 were included. Quality assessment was performed using A Measurement Tool to Assess Systematic Reviews (AMSTAR). Study characteristics were extracted, including journal and impact factor, year of publication, country affiliation, reporting adherence to Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, number of citations, and number of studies included.
    Results: The average AMSTAR score was moderate (5.32). There was a significant increase in AMSTAR score (P < 0.01) and number of studies (P < 0.01) over time. There were no significant correlations between AMSTAR score and impact factor (P = 0.038), and AMSTAR score and number of citations (P = 0.52), but there was a significant association between AMSTAR score and number of studies (P = 0.013). Studies that adhered to the PRISMA statement had a higher AMSTAR score on average (P < 0.01).
    Conclusions: Systematic reviews and meta-analyses about breast reconstruction had, on average, a moderate AMSTAR score. The number of studies and methodological quality have increased over time. Study characteristics including adherence to PRISMA guidelines are associated with improved methodological quality. Further improvements in specific AMSTAR domains would improve the overall methodological quality.
    DOI:  https://doi.org/10.1097/GOX.0000000000003897
  39. BMC Med Res Methodol. 2021 Nov 22. 21(1): 255
       BACKGROUND: The COVID-19 pandemic has severely affected health systems and medical research worldwide but its impact on the global publication dynamics and non-COVID-19 research has not been measured. We hypothesized that the COVID-19 pandemic may have impacted the scientific production of non-COVID-19 research.
    METHODS: We conducted a comprehensive meta-research on studies (original articles, research letters and case reports) published between 01/01/2019 and 01/01/2021 in 10 high-impact medical and infectious disease journals (New England Journal of Medicine, Lancet, Journal of the American Medical Association, Nature Medicine, British Medical Journal, Annals of Internal Medicine, Lancet Global Health, Lancet Public Health, Lancet Infectious Disease and Clinical Infectious Disease). For each publication, we recorded publication date, publication type, number of authors, whether the publication was related to COVID-19, whether the publication was based on a case series, and the number of patients included in the study if the publication was based on a case report or a case series. We estimated the publication dynamics with a locally estimated scatterplot smoothing method. A Natural Language Processing algorithm was designed to calculate the number of authors for each publication. We simulated the number of non-COVID-19 studies that could have been published during the pandemic by extrapolating the publication dynamics of 2019 to 2020, and comparing the expected number to the observed number of studies.
    RESULTS: Among the 22,525 studies assessed, 6319 met the inclusion criteria, of which 1022 (16.2%) were related to COVID-19 research. A dramatic increase in the number of publications in general journals was observed from February to April 2020 from a weekly median number of publications of 4.0 (IQR: 2.8-5.5) to 19.5 (IQR: 15.8-24.8) (p < 0.001), followed afterwards by a pattern of stability with a weekly median number of publications of 10.0 (IQR: 6.0-14.0) until December 2020 (p = 0.045 in comparison with April). Two prototypical editorial strategies were found: 1) journals that maintained the volume of non-COVID-19 publications while integrating COVID-19 research and thus increased their overall scientific production, and 2) journals that decreased the volume of non-COVID-19 publications while integrating COVID-19 publications. We estimated using simulation models that the COVID pandemic was associated with a 18% decrease in the production of non-COVID-19 research. We also found a significant change of the publication type in COVID-19 research as compared with non-COVID-19 research illustrated by a decrease in the number of original articles, (47.9% in COVID-19 publications vs 71.3% in non-COVID-19 publications, p < 0.001). Last, COVID-19 publications showed a higher number of authors, especially for case reports with a median of 9.0 authors (IQR: 6.0-13.0) in COVID-19 publications, compared to a median of 4.0 authors (IQR: 3.0-6.0) in non-COVID-19 publications (p < 0.001).
    CONCLUSION: In this meta-research gathering publications from high-impact medical journals, we have shown that the dramatic rise in COVID-19 publications was accompanied by a substantial decrease of non-COVID-19 research. META-RESEARCH REGISTRATION: https://osf.io/9vtzp/ .
    Keywords:  COVID-19; High-impact journals; Meta-research; Publications
    DOI:  https://doi.org/10.1186/s12874-021-01404-9
  40. Rev Assoc Med Bras (1992). 2021 Jul;pii: S0104-42302021000801069. [Epub ahead of print]67(7): 1069-1074
       OBJECTIVE: This study aimed to compare the publications authored by plastic surgeons with those from other specialties' surgeons on patient-reported outcomes of oncoplastic surgery.
    METHODS: A review was carried out on the Medline database, emcompassing five years (2015-2020). Studies about partial breast reconstruction after conservative treatment, immediate or delayed, by any technique, which presented patient-reported outcomes, were included.
    RESULTS: We found 292 articles, from which 142 met the eligibility criteria. Publications were stratified into groups 1 (plastic surgeons) and 2 (other surgical specialties), and also into groups A (only plastic surgeons), B (only other specialties) and C (both), and compared statistically. Most publications (60.6%) were attributed to specialties other than plastic surgery. Nineteen percent had only plastic surgeons as authors, 50% only other specialties' surgeons, and 31% had both. There was no difference between groups regarding the impact factor of the journals in any of the stratifications, and the majority was published in journals with impact factor ≤2. CONCLUSION: In the last years, surgeons from specialties other than plastic surgery published more about the results of the oncoplastic surgery reported by the patients. There was no statistical difference between the groups regarding the impact factor of the journals.
    DOI:  https://doi.org/10.1590/1806-9282.20210186
  41. Ann Intensive Care. 2021 Nov 27. 11(1): 165
       BACKGROUND: Critical care randomized controlled trials (RCTs) are often published in high-impact journals, whether general journals [the New England Journal of Medicine (NEJM), The Lancet, the Journal of the American Medical Association (JAMA)] or critical care journals [Intensive Care Medicine (ICM), the American Journal of Respiratory and Critical Care Medicine (AJRCCM), Critical Care Medicine (CCM)]. As rejection occurs in up to 97% of cases, it might be appropriate to assess pre-submission probability of being published. The objective of this study was to develop and internally validate a simplified score predicting whether an ongoing trial stands a chance of being published in high-impact general journals.
    METHODS: A cohort of critical care RCTs published between 1999 and 2018 in the three highest impact medical journals (NEJM, The Lancet, JAMA) or the three highest impact critical care journals (ICM, AJRCCM, CCM) was split into two samples (derivation cohort, validation cohort) to develop and internally validate the simplified score. Primary outcome was journal of publication assessed as high-impact general journal (NEJM, The Lancet, JAMA) or critical care journal (ICM, AJRCCM, CCM).
    RESULTS: A total of 968 critical care RCTs were included in the predictive cohort and split into a derivation cohort (n = 510) and a validation cohort (n = 458). In the derivation cohort, the sample size (P value < 0.001), the number of centers involved (P value = 0.01), mortality as primary outcome (P value = 0.002) or a composite item including mortality as primary outcome (P value = 0.004), and topic [ventilation (P value < 0.001) or miscellaneous (P value < 0.001)] were independent factors predictive of publication in high-impact general journals, compared to high-impact critical care journals. The SCOTI score (Sample size, Centers, Outcome, Topic, and International score) was developed with an area under the ROC curve of 0.84 (95% Confidence Interval, 0.80-0.88) in validation by split sample.
    CONCLUSIONS: The SCOTI score, developed and validated by split sample, accurately predicts the chances of a critical care RCT being published in high-impact general journals, compared to high-impact critical care journals.
    Keywords:  Critical care; Critically ill patients; Intensive care medicine; Intensive care unit; Precision medicine
    DOI:  https://doi.org/10.1186/s13613-021-00954-x
  42. J Crit Care. 2021 Nov 23. pii: S0883-9441(21)00253-7. [Epub ahead of print]
       PURPOSE: The established gender gap in intensive care medicine is larger compared to other medical specialties. The aim of this study was to evaluate gender distribution in boards of intensive care medicine societies worldwide.
    METHODS: In this cross-sectional analysis, board members and presidents of all intensive care medicine societies associated with the European Society of Intensive Care Medicine were eligible for study inclusion. Exclusion criteria were: A) society without focus on intensive care and B) online information unavailable.
    RESULTS: In 2021, 65 presidents and 820 board members were analyzed. Ten presidents (15%) and 231 board members (28%) were women. The proportion of women presidents reached from 0% in Africa to 20% in Europe and South America. The proportion of women board members was highest in North and South America with 42% and 46% respectively and lowest in Africa (21%) and Asia (10%). In Europe, 31% of board members were women and 35% in Australia/New Zealand. Among presidents, women were underrepresented in all continents while gender distribution among board members varied significantly between countries (p < 0.0001).
    CONCLUSION: Our analysis reveals an inequality in gender distribution in the boards of national intensive care medicine societies which varies but persists for all global regions.
    Keywords:  Critical care; Diversity; Gender; Gender disparities; Intensive care medicine
    DOI:  https://doi.org/10.1016/j.jcrc.2021.11.006
  43. Inquiry. 2021 Jan-Dec;58:58 469580211059469
      A specific and rational index system is key to scientific research evaluation. According to the characteristics and status of research-oriented hospitals in China, this study aimed to construct a comprehensive and methodical system for scientific research evaluation. Using bibliometric research, we sorted and refined indices for both domestic and international scientific research evaluation systems, established two-dimensional indices of input and output, and constructed the theoretical framework of evaluation after experts. The Delphi method was adopted to determine the evaluation indices at all levels, and the Analytic Hierarchy Process was used to calculate the weights of the indices at all levels. Twenty experts from different medical fields were involved in the 2 rounds study. Altogether, 7 primary, 14 secondary, and 37 tertiary indices were included in the evaluation system. A matrix was built to conduct the maximum eigenvalue, the consistency indices, and the consistency ratio of each expert in the survey. The index weight coefficients of the indices were calculated accordingly. The model exhibited high consistency, and the credibility of the results was verified. The evaluation system for research-oriented hospitals that we established had high specificity, credibility, and rationality. The evaluation system that we established combines some quantitative evaluation indicators, which are subsequently weighted according to their importance in the field of research-oriented hospital. Evaluation index system will provide the practical manner in the future for comparing the potential academic level and impact of research-oriented hospitals. Moreover, further verification, adjustments, and optimization of the system and indicators will be performed in follow-up empirical studies.
    Keywords:  Delphi method; analytic hierarchy process; evaluation index system; research-oriented hospital; scientific research
    DOI:  https://doi.org/10.1177/00469580211059469
  44. Sci Total Environ. 2021 Nov 19. pii: S0048-9697(21)06850-9. [Epub ahead of print] 151774
      The massive amounts of publication data are highly valuable, because in addition to the advancement in science, technology, and policy, such data can provide critical information and guidance on what have been published, what topical changes have evolved, and what are the trending fields deserving more attention. In the 21st century, biochar has played an indispensable role in the long-term global development strategies in response to "Carbon neutralization", "Agricultural management", and "Environmental restoration", and accumulated many high-quality publications. Herein, this study provides a new data-driven bibliometric analysis strategy and framework for mining the core content of massive literature data, and aims at bringing unique insights for the research prospects as well as opportunities of biochar. The results show that biochar researches have made great progress from 1999 to 2020, but cross-disciplinary teamwork should be further emphasized. The research frontier identification reveals that sewage treatment, efficient removal, and functional composite materials will be the issues which must be paid continual attention at present and in the future. Furthermore, studies on global climate impact, biomass resource utilization, carbon sequestration, carbon cycle, and even the negative effects of biochar have gradually begun to be taken seriously.
    Keywords:  Bibliometric study; Biochar; Data-driven analysis; Environmental technology; Mathematical methods
    DOI:  https://doi.org/10.1016/j.scitotenv.2021.151774
  45. Plast Reconstr Surg Glob Open. 2021 Oct;9(10): e3849
       Background: Evidence regarding whether medical school research portends resident research is limited. This information will provide program directors with data that may be useful for selecting applicants with a commitment to continued academic productivity.
    Methods: A questionnaire distributed via the American Society of Plastic Surgeons Resident Council to residents in 44 plastic surgery training programs in May 2020 assessed participation in dedicated research years during medical school, the number of publications completed before residency, and the total number of publications by each resident at the time of the survey. One-way ANOVA and post hoc analysis determined significant associations between publication count and number of research years.
    Results: Of the 256 included respondents, 203 did not complete a research year during medical school, 44 completed 1 research year, and nine completed 2 research years. Mean publications before residency were higher for participants who took 1 or 2 research years (9.88 and 27.60, respectively) compared with those who did not (4.83, P < 0.001). A comparison of total publications during residency similarly revealed increased productivity by individuals who took 1 or more research years; however, there was no difference between the number of publications completed during residency for individuals who took 1 versus 2 years (P = 0.23).
    Conclusions: Residents with research experience during medical school continue to produce an increased number of publications during residency compared with those without, suggesting dedicated research years taken during medical school serve as a predictor of academic productivity in plastic surgery residents.
    DOI:  https://doi.org/10.1097/GOX.0000000000003849
  46. Front Aging Neurosci. 2021 ;13 766587
      Neurodegenerative diseases, namely Alzheimer's (AD), Parkinson's (PD), and Huntington's disease (HD) together with amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), devastate millions of lives per year worldwide and impose an increasing socio-economic burden across nations. Consequently, these diseases occupy a considerable portion of biomedical research aiming to understand mechanisms of neurodegeneration and to develop efficient treatments. A potential culprit is cholesterol serving as an essential component of cellular membranes, as a cofactor of signaling pathways, and as a precursor for oxysterols and hormones. This article uncovers the workforce studying research on neurodegeneration and cholesterol using the TeamTree analysis. This new bibliometric approach reveals the history and dynamics of the teams and exposes key players based on citation-independent metrics. The team-centered view reveals the players on an important field of biomedical research.
    Keywords:  bibliometric analyses; informetric; key opinion leader; neurologic disease; research evaluation; scientific impact; scientometric; sterol
    DOI:  https://doi.org/10.3389/fnagi.2021.766587
  47. Pharmaceutics. 2021 Nov 06. pii: 1885. [Epub ahead of print]13(11):
      Intra-arterial drug delivery circumvents the first-pass effect and is believed to increase both efficacy and tolerability of primary and metastatic brain tumor therapy. The aim of this update is to report on pertinent articles and clinical trials to better understand the research landscape to date and future directions. Elsevier's Scopus and ClinicalTrials.gov databases were reviewed in August 2021 for all possible articles and clinical trials of intra-arterial drug injection as a treatment strategy for brain tumors. Entries were screened against predefined selection criteria and various parameters were summarized. Twenty clinical trials and 271 articles satisfied all inclusion criteria. In terms of articles, 201 (74%) were primarily clinical and 70 (26%) were basic science, published in a total of 120 different journals. Median values were: publication year, 1986 (range, 1962-2021); citation count, 15 (range, 0-607); number of authors, 5 (range, 1-18). Pertaining to clinical trials, 9 (45%) were phase 1 trials, with median expected start and completion years in 2011 (range, 1998-2019) and 2022 (range, 2008-2025), respectively. Only one (5%) trial has reported results to date. Glioma was the most common tumor indication reported in both articles (68%) and trials (75%). There were 215 (79%) articles investigating chemotherapy, while 13 (65%) trials evaluated targeted therapy. Transient blood-brain barrier disruption was the commonest strategy for articles (27%) and trials (60%) to optimize intra-arterial therapy. Articles and trials predominately originated in the United States (50% and 90%, respectively). In this bibliometric and clinical trials analysis, we discuss the current state and trends of intra-arterial therapy for brain tumors. Most articles were clinical, and traditional anti-cancer agents and drug delivery strategies were commonly studied. This was reflected in clinical trials, of which only a single study had reported outcomes. We anticipate future efforts to involve novel therapeutic and procedural strategies based on recent advances in the field.
    Keywords:  brain tumor; chemotherapy; drug delivery; glioma; immunotherapy; injection; intra-arterial; nanoparticles; targeted therapy; treatment
    DOI:  https://doi.org/10.3390/pharmaceutics13111885
  48. Bioengineering (Basel). 2021 Oct 26. pii: 159. [Epub ahead of print]8(11):
      Stem cell therapy has been considered a promising strategy in the management of both type I and type II diabetes mellitus (DM) because of its immunomodulatory and regenerative capability to restore the beta cell number and function. Various modalities of cellular therapy like transplantation of pancreatic islet cells, transplantation of pancreatic ductal stem cells, and mesenchymal stromal cell transplantation have been tried, and the modality is undergoing rapid advancements that may become the reality in the near future. In the course of its evolution, it is essential to have a comprehensive summary of the progress for a greater capacity to refine our future directives. With technological developments like data mining, graphic drawing, and information analytics combined with computational statistics, visualization of scientific metrology has become a reality. With a newer perspective, we intend to use scientometric tools including text mining, co-word analysis, word frequency analysis, co-citation analysis, cluster network analysis, to perform a systematic and comprehensive analysis of the research trend in stem cell therapy in the management of DM over the past three decades (1990-2020) and to identify the future research hotspots.
    Keywords:  diabetes mellitus; scientometric research; stem cell; therapy; trend analysis
    DOI:  https://doi.org/10.3390/bioengineering8110159
  49. J Surg Educ. 2021 Nov 17. pii: S1931-7204(21)00315-9. [Epub ahead of print]
       OBJECTIVE: Rankings of residency programs are highly influential and utilized by residency applicants. Existing ranking resources often use opaque criteria that may include bias or do not accurately represent the academic achievement of current faculty. This study aims to create an updated general surgery residency ranking list based on the academic achievements of their respective surgery department faculty members.
    DESIGN: One hundred and six general surgery residency programs were selected from the American Medical Association Residency & Fellowship Programs Database. The names of faculty members affiliated with the departments of surgery were manually obtained. Lifetime and five-year h-indexes, a sum of grant awards from the National Institute of Health and Veterans Affairs, and a tally of journal editorial board positions were collected for the faculty. Metrics were compared among surgical departments, and the corresponding residency programs were ranked accordingly.
    SETTING: The study evaluated university-based general surgery residency programs in the United States from 2017 to 2019 via assessing their respective institutions' departments of surgery.
    PARTICIPANTS: A total of 7568 faculty members were evaluated. Faculty were required to be full-time, clinical surgeons to meet inclusion criteria.
    RESULTS: Based on a composite of all measured criteria, the top overall surgery department was at the University of Michigan. Massachusetts General Hospital had the highest lifetime and five-year h-indexes. Brigham and Women's Hospital had the most National Institute of Health funding, and the University of Pittsburgh Medical Center had the most Veterans Affairs funding. Washington University in St. Louis/Barnes Jewish Hospital had the most editorial board positions in their department.
    CONCLUSIONS: The academic success of departments of surgery was evaluated to develop a ranking list of general surgery residency programs. Through utilizing standardized methods and several measures of academic achievement, this comprehensive general surgery residency classification system will allow residency applicants to make more informed decisions.
    Keywords:  Interpersonal and Communication Skills; Medical knowledge; Practice-based Learning and Improvement; Professionalism; Systems-based Practice; department; faculty; h-index; ranking; residency; surgery
    DOI:  https://doi.org/10.1016/j.jsurg.2021.10.015