bims-evares Biomed News
on Evaluation of research
Issue of 2021–10–24
forty-six papers selected by
Thomas Krichel, Open Library Society



  1. World Neurosurg. 2021 Oct 15. pii: S1878-8750(21)01594-1. [Epub ahead of print]
       BACKGROUND: Acta Neurochirurgica, (ANCH) and World Neurosurgery (WN), are two journals of significant importance in the neurosurgical community and have been associated with international federations. Of note is that these journals carry a similar impact factor. The difference is the years they have been active (ANCH starting publications in 1973 and WN in 2010). This allows for a unique opportunity to delve deep into comparative, scientometric parameters, to understand the evolution of neurosurgical research.
    METHODS: A title specific search of the Web of Science database using the keywords 'ACTA NEUROCHIRURGICA', 'Acta' and 'Neurochirurgica'; 'World Neurosurgery'; 'World' and 'Neurosurgery' was done and arranged according to number of citations. Title of the articles, authors, corresponding authors, country of origin, journal of publication, year of publication, citation count and the journal impact factor were assessed.
    RESULTS: The average citation for ANCH was 170.1 citations, majority being original articles (83/100). The articles of WN, garnered nearly 70.48 citations, averaging 8.3 citations per publication. Most corresponding authors in Acta originated from Germany with Neuro-oncology, followed by Neurotrauma and Vascular as subjects. In contrast the United States of America followed by China were the most common countries of origin for WN with 'Endoscopy' and 'Skull-base' being the topics achieving high impact.
    CONCLUSIONS: Neurotrauma and consensus guidelines have been shown to have maximal citations for ANCH while Endoscopy and Skull-base lesions garnered the most for WN. Author subspecialisation and increased collaboration across specialities with more articles on refinement of technique and outcome have emerged as recent trends.
    Keywords:  Acta Neurochirurgica; Bibliometric analysis; Citation analysis; Impact Factor; World Neurosurgery
    DOI:  https://doi.org/10.1016/j.wneu.2021.10.099
  2. J Nucl Med. 2021 Oct 21. pii: jnumed.121.262773. [Epub ahead of print]
      Despite the feminization of the medical workforce, women do not have the same career perspectives as men. In nuclear medicine, little information is available on the gender gap regarding prominent author positions of scientific articles. Therefore, the purpose of this study was to evaluate recent trends in the gender distribution of first and last authorship of articles published in nuclear medicine journals. Methods: We conducted a bibliometric analysis of first and last author gender of articles published from 2014 to 2020 in 15 nuclear medicine journals. Manuscript title, article type, journal impact factor, date of publication, first and last name and country of provenance of first and last authors were noted. The Gender-API software was used to determine author gender. All statistics were descriptive. Results: Women represented 32.8% of first authors and 19.6% of last ones. Female authorship increased from 28.2% (428 of 1518 articles) in 2014 to 35.5% (735 of 2069 articles, relative increase 72%) in 2020 (p<0.001) for first authors and from 15.6% (237 of 1518 articles) in 2014 to 20.5% (424 of 2069 articles, relative increase 79%) in 2020 (p<0.001) for last ones. Parity was forecasted in 2035 for first authors and in 2052 for last ones. Female authorship increased in Europe for first (P = 0.014) and last authors (p<0.001), in high-ranking journals for first (P = 0.004) and last authors (p<0.001) and in other journal ranks for last authors (P = 0.01). Female first and last authorship rose for original articles (P = 0.02 and P = 0.01 respectively) and case reports (p<0.001 and P = 0.002 respectively). Regarding collaborations, the proportion of articles produced by male first and last authors decreased from 62.2% in 2014 to 52.9% in 2020 in favor of female first and last authors (OR=1.07, p<0.001), male first and female last authors (OR =1.05, p<0.001) and female first and male last authors (OR=1.03, p<0.001). Conclusion: Female first and last authorship in nuclear medicine journals increased substantially from 2014 to 2020, in particular in high-ranking journals, in Europe and for original articles and case reports. Male/male collaborations decreased by 10% in favor of all other collaborations. Parity can be foreseen in a few decades.
    Keywords:  Authorship; Nuclear Medicine; Other; Physicians; Women
    DOI:  https://doi.org/10.2967/jnumed.121.262773
  3. Front Oncol. 2021 ;11 744308
       Background: Craniopharyngioma (CP) is a challenging intracranial tumor due to its special hypothalamus-pituitary location. Each patient with CP should be evaluated and treated separately. Exploring novel methods of automatized analysis of data for gaining knowledge on any medical field is an encouraging task, particularly in such an extremely challenging tumor as CP. We aim to summary the situations, investigate the research trends and evaluate research hotspots using bibliometric analysis for the CP research.
    Methods: We extracted all the CP-related literatures from 2011 to 2020 from the Web of Science database. An Online analysis platform of literature metrology (Bibliometric), BICOMB, gCLUTO and CiteSpace softwares were used to do bibliometric analysis. As a supplement, we also analyzed the top 100 cited case reports with particular and certainly infrequent information to improve the analysis.
    Results: According to our retrieval strategy, we found a total of 1262 CP-related literatures. The United States has maintained a leading position in global CP research, followed by China and Germany. Among institutions, Capital Med Univ, St Jude Childrens Res Hosp and Southern Med Univ rank in the top 3 in terms of the number of articles published. "WORLD NEUROSURGERY" is the most popular journal for CP-related research. Moreover, MULLER HL, MERCHANT TE, QI ST and others have made great achievements in the study of CP. Finally, we did biclustering analysis on keywords and identified 4 CP research hotspot clusters.
    Conclusions: Our research provides a comprehensive analysis of the scientific progress of CP in the past 10 years, and insight into the development of CP research field, highlight research trends over time, and help identify valuable future directions.
    Keywords:  bibliometrics; citation; craniopharyngioma; hotspots; trends
    DOI:  https://doi.org/10.3389/fonc.2021.744308
  4. Front Med (Lausanne). 2021 ;8 658833
      Background: Publication activity in the field of anesthesiology informs decisions that enhance academic advancement. Most previous bibliometric studies on anesthesiology examined data limited to journals focused on anesthesiology rather than data answerable to authors in anesthesia departments. This study comprehensively explored publication trends in the field of anesthesiology and their impact. We hypothesized that anesthesiology's bibliometric scene would differ based on whether articles in the same study period were published in anesthesiology-focused journals or were produced by authors in anesthesia departments but published in non-specialty journals. Methods: This cross-sectional study used bibliometric data from the Science Citation Index Expanded database between 1999 and 2018. Two datasets were assembled. The first dataset was a subject-dataset (articles published in 31 journals in the anesthesiology category of InCites Journal Citation Reports in 2018); the second dataset was the department-dataset (articles published in the Science Citation Index Expanded by authors in anesthesia departments). We captured the bibliographical record of each article in both datasets and noted each article's Institute for Scientific Information code, publication year, title, abstract, author addresses, subject category, and references for further study. Results: A total of 69,593 articles were published-cited 1,497,932 times-in the subject-dataset; a total of 167,501 articles were published-cited 3,731,540 times-in the department-dataset. The results demonstrate differences between the two datasets. First, the number of articles was stagnant, with little growth (average annual growth rate = 0.31%) in the subject-dataset; whereas there was stable growth (average annual growth rate = 4.50%) in articles in the department-dataset. Second, only 30.4% of anesthesia department articles were published in anesthesiology journals. Third, journals related to "pain" had the lowest department-subject ratio, which was attributable to a large portion of non-anesthesia department researchers' participation in related research. Conclusions: This study showed that articles published in anesthesiology-focused and non-specialty journals demonstrate fundamentally different trends. Thus, it not only helps researchers develop a more comprehensive understanding of the current publication status and trends in anesthesiology, but also provides a basis for national academic organizations to frame relevant anesthesiology development policies and rationalize resource allocation.
    Keywords:  anesthesia; anesthesiology; bibliometrics; informetrics; research evaluation; scientometrics
    DOI:  https://doi.org/10.3389/fmed.2021.658833
  5. Front Pharmacol. 2021 ;12 731757
      Introduction: Pharmacovigilance studies include monitoring and preventing the occurrence of new, rare, or serious adverse drug reactions, making it possible to discover new safety issues without delay. Bibliometrics could assist scholars to analyze the development of pharmacovigilance. Methods: The MeSH terms of both pharmacovigilance and "adverse drug reaction reporting system" were retrieved in the Science Citation Index Expanded. The articles from 1974 to July 2021 in the pharmacology and pharmacy category were recruited. The citation reports including the publication numbers, h-index, and sum and average cited times in terms of annuals, countries, organizations, authors and journals were tabulated. The coauthorship relations in the analysis units of countries, organizations, and authors; the top 10 burst references; the document citation network; and the author's keywords co-occurrence overlay map were visualized by bibliometric software including the website (https://bibliometric.com/), VOSviewer, CiteSpace, and CitNetExplorer. Results: From 1974 to the present, the most high-yield publication year, country, institute, author, and journal were 2020 (n = 222), France (n = 522), Netherlands Pharmacovigilance Centre Lareb (n = 82), Jean-Louis Montastruc (n = 125), Drug Safety (n = 384), respectively, in all 2,128 articles. Similarly, the United States, Institut National de la Sante et de la Recherche Medicale, and Jean-Louis Montastruc had the most coauthorship strength at the macrolevel (global), mesolevel (local), and microlevel (individual). The topics of burst references covered are the development of methodology, issues of patients reporting and under-reporting, evaluation of methods and databases, assessment of causality, and perspectives in pharmacovigilance. Eight clusters were grouped in the document citation network. "Pharmacovigilance," "adverse drug reactions," "pharmacoepidemiology," "drug safety," and "signal detection" were the research priorities, while "drug-related side effects and adverse reactions," "VigiBase," "disproportionality analysis," "social media," "FAERS," "chemotherapy," "patient safety," "reporting odds ratio," and "preventability" might be the future research hotspots. Conclusion: Positive synergies can be observed in this study by employing the multiple software tools which established the relationship between the units of analysis. The bibliometric analysis can organize the thematic development and guide the hotspots of pharmacovigilance in pharmacology and pharmacy.
    Keywords:  bibliometrics; pharmacoepidemiolgy; pharmacology and pharmacy; pharmacovigilance; visualization
    DOI:  https://doi.org/10.3389/fphar.2021.731757
  6. Pathogens. 2021 Oct 18. pii: 1343. [Epub ahead of print]10(10):
      Vancomycin is frequently prescribed in pediatrics, especially in intensive care unit settings, to treat Gram-positive bacterial infections. This work aims to collect the top-cited articles of pediatric and infectious diseases areas to gather the current evidence and gaps of knowledge on the use of vancomycin in these populations. The most relevant journals reported in the "pediatrics" and "infectious diseases" categories of the 2019 edition of Journal Citation Reports were browsed. Articles with more than 30 citations and published over the last three decades were collected. A bibliometric analysis was performed and 115 articles were retrieved. They were published in 21 journals, with a median impact factor of 4.6 (IQR 2.9-5.4). Sixty-eight of them (59.1%) belonged to "infectious diseases" journals. The most relevant topic was "bloodstream/complicated/invasive infections", followed by "antibiotic resistance/MRSA treatment". As for population distribution, 27 articles were on children only and 27 on neonates, most of which were from intensive care unit (ICU) settings. The current literature mainly deals with vancomycin as a treatment for severe infections and antibiotic resistance, especially in neonatal ICU settings. Lately, attention to new dosing strategies in the neonatal and pediatric population has become a sensible topic.
    Keywords:  bibliometric analysis; children; neonates; pediatric infectious diseases; top-cited articles; vancomycin
    DOI:  https://doi.org/10.3390/pathogens10101343
  7. J Pain Res. 2021 ;14 3207-3221
      A bibliometric approach using network analytical methods was applied to explore the research trends on acupuncture for neck pain treatment. Publications related to acupuncture for neck pain treatment from 2000 to 2020 were retrieved from the Web of Science database. The extracted records were analyzed in terms of publication year, research area, journal title, country, organization, authors, and keywords. The research trends on acupuncture for neck pain treatment were visualized using the VOSviewer program. Analyses of 325 articles revealed that the total number of publications has continually increased over the last 20 years. The most represented research area was integrative complementary medicine. The country producing the most articles was the US, followed by China, England, and the Republic of Korea. By assessing the total link strength of organizations and authors, we identified influential organizations and authors who have contributed to research on acupuncture for neck pain treatment. A network analysis based on the cooccurrence of keywords revealed the following two major study designs: clinical study and research methodology. This study examined the research trends on acupuncture for neck pain treatment using bibliometric methods. Our findings provide useful guidelines for researchers in searching for relevant topics.
    Keywords:  acupuncture; bibliometric analysis; cervical pain; neck pain; network analysis
    DOI:  https://doi.org/10.2147/JPR.S331514
  8. Trans R Soc Trop Med Hyg. 2021 Oct 14. pii: trab161. [Epub ahead of print]
       BACKGROUND: Research plays a significant role in quantifying and addressing the burden of disease, improving healthcare delivery and developing evidence-based policy for neglected tropical diseases (NTDs). Since noma is not a recognised NTD by the World Health Organization (WHO), research activity is hypothesised to be low. This study aims to understand patterns and trends of research conducted on noma, to understand the patterns of citations, highlight networks of collaboration and analyse stakeholders in noma research.
    METHODS: The SCOPUS database was selected and searched. Data analysis was conducted using the bibliometrix package for R in RStudio. Areas of interest included the distribution of research output on noma by year and location, the academic impact of publication output, mapping the major academic community and conducting a thematic analysis of high-frequency keywords.
    RESULTS: A total of 208 documents were identified. The annual growth rate of publications is 4.3%. The average number of citations per publication was 11.0 (rounded from 10.98) and the average citations per year per publication was 0.57. The USA was the country with the highest percentage 10.6% (n=22) of corresponding authors, followed by Nigeria (6.7% [n=14]), the UK (6.3% [n=13]) and India (5.8% [n=12]). For those papers with multiple authors, there was an average of 3.22 co-authors per document. The collaboration index was 3.3. Upon plotting collaboration networks between authors, only 11 clusters were identified (frequency and intensity of collaboration). Mapping of trending topics showed a focus on skin grafting and transplantation within the literature.
    CONCLUSIONS: In order to progress towards eventual elimination of noma it is key that more research should be undertaken and more interest and funding should be dedicated to work on noma. Recognition of noma as an NTD by the WHO would be a first step in moving towards increased awareness.
    Keywords:  bibliometric analysis; cancrum oris; neglected tropical diseases; noma; orofacial gangrene
    DOI:  https://doi.org/10.1093/trstmh/trab161
  9. Therap Adv Gastroenterol. 2021 ;14 17562848211042170
      A bibliometric analysis was performed using a machine learning bibliometric methodology in order to evaluate the research trends in locally advanced rectal cancer treatment between 2000 and 2020. Information regarding publication outputs, countries, institutions, journals, keywords, funding, and citation counts was retrieved from Scopus database. During the search process, a total of 2370 publications were identified. The vast majority of papers originated from the United States of America, reflecting also its research drive in the collaboration network. Neoadjuvant treatment was the topic most studied in the highly cited studies. New keywords, including neoadjuvant chemotherapy, multiparametric magnetic resonance imaging, circulating tumor DNA, and genetic heterogeneity, appeared in the last 2 years. The quantity of publications on locally advanced rectal cancer treatment since 2000 showed an evolving research field. The 'new' keywords explain where research is presently heading.
    Keywords:  bibliometric analysis; chemotherapy; machine learning; radiotherapy; rectal cancer; surgery
    DOI:  https://doi.org/10.1177/17562848211042170
  10. Qual Quant. 2021 Oct 12. 1-31
      This study adopts the bibliometric approach to identify the key characteristics in the relationship of demographic factors (age, gender, affiliations, and locations), scientific productivity, and the collaboration among development economics researchers in Vietnam during the period 2008-2020. Overall, the number of publications and authors in development economics are rising steeply with the average annual growth rate of nearly 23% and 26%, respectively. Moreover, the 'quality' of the research appears to be high as 59% of the articles are published in journals in the first and second quartile according Scimago journal ranking. However, the citation counts for these studies indicate their impacts are far more languishing in comparison. In terms of research trends, this study identified three emerging areas of studies that are relatively under-researched, namely natural resources, technology, and urbanization. As for publishing practices, There is also a positive sign for the adoption of open science among Vietnamese researchers in this field. The findings are useful for predicting future research trends. In addition, the study provides several implications for policymakers in Vietnam to enhance research capacity.
    Keywords:  Bibliometrics; Development economics; Open access; Vietnam scientific productivity
    DOI:  https://doi.org/10.1007/s11135-021-01258-9
  11. Int J Environ Res Public Health. 2021 Oct 15. pii: 10857. [Epub ahead of print]18(20):
      Resilience is an important issue in urban development, and community resilience (CR) is the most typical representative in building urban resilience, which has become the forefront of international resilience research. This paper presents a bibliometric and visual analysis of community resilience research collected from the WoS Core Collection database over the past two decades. H-index, citation frequency, centrality and starting year were adopted to analyze the research objects by bibliometric tools including CiteSpace, VOSviewer, and Gephi. The national and institutional characteristics of macro-geographical distribution and the characteristics of disciplines, journals, authors, and author cooperation of micro-knowledge network distribution were revealed. Finally, the potential research directions of community resilience in the future were discussed. The results show that there are three stages in community resilience research. Seven intellectual bases constitute the research background for community resilience, including social capital mechanism, the evolution of resilience knowledge, earthquake resistance and disaster mitigation, substance abuse, resilient development in rural communities, resilience-building in the least-developed countries, and emergency preparedness. Our analysis shows that the hottest community resilience research topics are the concept of resilience, climate resilience, the social capital mechanism, macro-environment and disaster-reduction policies, and an evaluation index system for community resilience.
    Keywords:  bibliometric analysis; community resilience; hotspots; urban development
    DOI:  https://doi.org/10.3390/ijerph182010857
  12. Jpn J Nurs Sci. 2021 Oct 17. e12458
       AIM: The characteristics of the publications on nursing empowerment should be investigated in order to get an idea about the development of the field and to determine the developments in nursing practices and research. This study aimed to investigate the characteristics of the current knowledge structure and developmental process in nurse empowerment by using bibliometric methods.
    METHODS: The data of this retrospective descriptive study were obtained from the Web of Science (WoS). All relevant studies conducted before 2020 were included in the study. The data analysis was conducted with Excel, SPSS and VOSviewer.
    RESULTS: Five hundred eighty-nine studies conducted between 1974-2019 were included in the study. It was found that 72.15% of these studies were journal articles and these studies were conducted by 1,450 authors. The studies were published in 109 journals and were produced by researchers from 49 different countries. Also 47.5% of these studies were conducted in the United States. Hot topics were "empowerment", "nursing," "structural empowerment," "nurses," "job satisfaction" and "psychological empowerment."
    CONCLUSION: There has been a noteworthy increase in the number of studies on nurse empowerment and this field offers an active field of study for nursing researchers. The focus of the studies varies from nurses to nurse managers.
    Keywords:  bibliometric analysis; hot topics; nurse empowerment; nursing; research trends
    DOI:  https://doi.org/10.1111/jjns.12458
  13. Manag Int Rev. 2021 Oct 13. 1-44
      The Management International Review (MIR) celebrated its 60th anniversary in 2020. In commemoration of this event, we use a bibliometric analysis to present a retrospective on the journal by analyzing its content for the years between 2006 and 2020. We find that the collaboration culture in MIR has risen over time with the increase in the median size of author teams. Moreover, the collaboration network has become more global over time. The methodology used in the journal is predominantly empirical and quantitative with archival data sources most commonly used. The bibliographic coupling of the MIR corpus reveals that the major themes in the journal revolve around "culture," "emerging economies," "innovation, knowledge transfer, and absorptive capacity," "internationalization process," "culture and entry modes," and "internationalization and performance." A comparison with other leading international business journals provides distinct pathways in which MIR may continue to grow. Finally, it is important to note that while the share of conceptual studies has decreased significantly in the last 15 years, the MIR editors want to see more novel and theoretically grounded conceptual articles in the journal.
    Keywords:  Bibliographic coupling; Bibliometric analysis; Co-authorship analysis; International business; International management
    DOI:  https://doi.org/10.1007/s11575-021-00454-x
  14. Eur Arch Paediatr Dent. 2021 Oct 21.
       AIM: To identify the worldwide trends in scientific evidence and gaps in knowledge regarding molar incisor hypomineralisation (MIH) and deciduous molar hypomineralisation/hypomineralised second primary molars (DMH/HSPM), exploring the contribution of authors and countries, possible etiological factors and proposed treatments, in order to guide future research in the area.
    METHODS: Searches were conducted in MEDLINE, Scopus, Web of Science, Cochrane Library, Lilacs/BBO, Embase and Google Scholar. Studies employing the terms MIH, DMH/HSPM and their linguistic variations were included. The following data were extracted: title, authors, year and journal of publication and first author's affiliation country. Studies were categorized according to topic, dentition, study design, etiological factors and types of treatments. Categories were analysed in relation to their distribution, co-occurrence, cross-correlation and/or autocorrelation.
    RESULTS: Five hundred and three studies were included. The most published authors were Manton D (n = 47), de Souza JF (n = 22) and Ghanim A (n = 22) and four main collaboration clusters have been identified. Most of the studies were conducted on permanent dentition (MIH) (87.4%); with observational design (57.2%). The "European Archives of Paediatric Dentistry" was the most published journal (13.3%) and a significant increase in the number of publications was observed in the last decade. MIH was most studied in relation to prevalence/incidence, systemic factors involved in its aetiology and treatment with composite restorations, while a gap in knowledge was observed for extraction and sealants. Less studies were published on DMH/HSPM and most of them evaluated risk factors or prevalence/incidence. The gap of knowledge was observed in relation to treatments and patient's quality of life.
    CONCLUSIONS: This bibliometric review provided a comprehensive overview of research in MIH and DMH/HSPM over the past 19 years. Within the limitations of the present study, the following conclusions can be drawn: global trends point to an increasing peak of scientific publication, especially in the last decade, while there is a shortage of clinical studies on treatments, mainly evaluating tooth extractions. Finally the multifactorial nature should be further explored, considering environmental and systemic factors together.
    Keywords:  Bibliometrics; Demarcated opacity; Dental enamel hypoplasia; Hypomineralised second primary molar; Molar incisor hypomineralisation
    DOI:  https://doi.org/10.1007/s40368-021-00676-5
  15. Med Teach. 2021 Oct 22. 1-11
       INTRODUCTION: The American Medical Association formed the Accelerating Change in Medical Education Consortium through grants to effect change in medical education. The dissemination of educational innovations through scholarship was a priority. The objective of this study was to explore the patterns of collaboration of educational innovation through the consortium's publications.
    METHOD: Publications were identified from grantee schools' semi-annual reports. Each publication was coded for the number of citations, Altmetric score, domain of scholarship, and collaboration with other institutions. Social network analysis explored relationships at the midpoint and end of the grant.
    RESULTS: Over five years, the 32 Consortium institutions produced 168 publications, ranging from 38 papers from one institution to no manuscripts from another. The two most common domains focused on health system science (92 papers) and competency-based medical education (30 papers). Articles were published in 54 different journals. Forty percent of publications involved more than one institution. Social network analysis demonstrated rich publishing relationships within the Consortium members as well as beyond the Consortium schools. In addition, there was growth of the network connections and density over time.
    CONCLUSION: The Consortium fostered a scholarship network disseminating a broad range of educational innovations through publications of individual school projects and collaborations.
    Keywords:  Social network; consortium; undergraduate medical education
    DOI:  https://doi.org/10.1080/0142159X.2021.1985096
  16. BMJ Open. 2021 Oct 18. 11(10): e046618
       OBJECTIVE: We evaluated the temporal trend in gender ratios of first and last authors in the field of oncological research published in major general medical and oncology journals and examined the gender pattern in coauthorship.
    DESIGN: We conducted a retrospective study in PubMed using the R package RISmed. We retrieved original research articles published in four general medical journals and six oncology specialty journals. These journals were selected based on their impact factors and popularity among oncologists. We identified the names of first and last authors from 1 January 2002 to 31 December 2019. The gender of the authors was identified and validated using the Gender API database (https://gender-api.com/).
    PRIMARY AND SECONDARY OUTCOME MEASURES: The percentages of first and last authors by gender and the gender ratios (male to female) and temporal trends in gender ratios of first and last authors were determined.
    RESULTS: We identified 34 624 research articles, in which 32 452 had the gender of both first and last authors identified. Among these 11 650 (33.6%) had women as the first author and 7908 (22.8%) as the last author, respectively. The proportion of female first and last authors increased from 26.6% and 16.2% in 2002, to 32.9% and 27.5% in 2019, respectively. However, the gender ratio (male to female) of first and last authors decreased by 1.5% and 2.6% per year, respectively, which were statistically significant (first author: incidence rate ratio (IRR) 0.98, 95% CI 0.97 to 1.00; last author: IRR 0.97, 95% CI 0.96 to 0.99). Male first and last authorship was the most common combination. Male-female and female-female pairs increased by 2.0% and 5.0%, respectively (IRR 1.02, 95% CI 1.01 to 1.03 and IRR 1.05, 95% CI 1.04 to 1.06, respectively).
    CONCLUSIONS: The continued under-representation of women means that more efforts to address parity for advancement of women in academic oncology are needed.
    Keywords:  adult oncology; epidemiology; statistics & research methods
    DOI:  https://doi.org/10.1136/bmjopen-2020-046618
  17. J Surg Educ. 2021 Oct 19. pii: S1931-7204(21)00249-X. [Epub ahead of print]
       OBJECTIVE: Advanced clinical fellowship training has become a popular option for surgical trainees seeking to bolster their clinical training and expertise. However, the long-term academic impact of this additional training following a traditional thoracic surgery fellowship is unknown. This study aimed to delineate the impact of an advanced clinical fellowship on subsequent research productivity and advancement in academic career among general thoracic surgeons.
    METHODS: Using an internally constructed database of active, academic general thoracic surgeons who are current faculty at accredited cardiothoracic surgery training programs within the United States, surgeons were dichotomized according to whether an advanced clinical fellowship was completed or not. Academic career metrics measured by research productivity, scholarly impact (H-index), funding by the National Institutes of Health, and academic rank were compared.
    RESULTS: Among 285 general thoracic surgeons, 89 (31.2%) underwent an advanced fellowship, whereas 196 (68.8%) did not complete an advanced fellowship. The most commonly pursued advanced fellowship was minimally invasive thoracic surgery (32.0%). There were no differences between the two groups in terms of gender, international medical training, or postgraduate education. Those who completed an advanced clinical fellowship were less likely to have completed a dedicated research fellowship compared to those who had not completed any additional clinical training (58.4% vs. 74.0%, p = 0.0124). Surgeons completing an advanced clinical fellowship demonstrated similar cumulative first-author publications (p = 0.4572), last-author publications (p = 0.7855), H-index (p = 0.9651), National Institutes of Health funding (p = 0.7540), and years needed to advance to associate professor (p = 0.3410) or full rank professor (p = 0.1545) compared to surgeons who did not complete an advanced fellowship. These findings persisted in sub-analyses controlling for surgeons completing a dedicated research fellowship.
    CONCLUSIONS: Academic general thoracic surgeons completing an advanced clinical fellowship demonstrate similar research output and ascend the academic ladder at a similar pace as those not pursuing additional training.
    Keywords:  Advanced clinical fellowship; Career; Education; Research; Thoracic Surgery; Training
    DOI:  https://doi.org/10.1016/j.jsurg.2021.09.003
  18. Sci Total Environ. 2021 Oct 14. pii: S0048-9697(21)06049-6. [Epub ahead of print] 150971
      
    Keywords:  Bibliometric; Scientometric; Web of Science
    DOI:  https://doi.org/10.1016/j.scitotenv.2021.150971
  19. Ann Palliat Med. 2021 Oct 09. pii: apm-21-1682. [Epub ahead of print]
      Radiotherapy is one of the common means of cancer treatment, especially in the treatment of lung cancer. However, radiation therapy can cause lung tissue radiation lung injury. The study of this disease can reduce its incidence and avoid the occurrence of radiation pulmonary fibrosis. In the past 20 years, the study of radiation-induced lung injury (RILI) has attracted more attention. This paper extracts the main text information of RILI-related literature from WOSCC database from 2001 to 2020, uses Citespace and VOSviewer for visual analysis, and presents the results. We found that in the past 20 years, there have been 4,665 articles on RILI, and the number of articles published reached a peak in 2017. The United States is the main leader in this research field, among which UNIV Texas MD Anderson Cancer Center has published many research results in this field. The most active author is Liao Zhongxing, and the most influential journal is Int J Radiat Oncol, which provides a platform for scholars in related fields to publish their articles. Current research focuses mainly on randomized controlled trials related to RILI, the relationship between dose-volume histogram analysis and RILI formation, the protection of normal lung tissue, the effect of stereoscopic radiotherapy on RILI and the pathogenesis of RILI. In the study of the formation mechanism of RILI, the main research directions include the apoptosis mechanism of epithelial and endothelial cells, cytokine cascade theory, immune mechanism regulation process, oxidative stress mechanism, etc.
    Keywords:  CiteSpace; Radiation-induced lung injury (RILI); VOSviewer; bibliometric; visual analysis
    DOI:  https://doi.org/10.21037/apm-21-1682
  20. J Bioeth Inq. 2021 Oct 21.
      
    Keywords:  Publications; Racism; Scholarly citations
    DOI:  https://doi.org/10.1007/s11673-021-10137-9
  21. J Neurosurg. 2021 Oct 22. pii: 2021.6.JNS21474. [Epub ahead of print] 1-8
       OBJECTIVE: At present, females constitute less than 10% of neurosurgeons in the US, despite representing approximately half of all medical students. Multiple barriers have been described for females entering the neurosurgical field, particularly academic neurosurgery. Understanding the environment that female neurosurgeons face and any potential barriers preventing career advancement is needed to recruit, promote, and retain females in neurosurgery.
    METHODS: The gender composition of editorial boards for 5 high-impact neurosurgery journals was analyzed from 2000 to 2020. The names of editorial board members were obtained directly from the journal administration, physical copies of the published journal, or publicly available data through each journal's website. The gender, degrees, academic titles, H-index, and country were determined for each individual and statistical tests were performed to identify significant differences.
    RESULTS: Of the 466 identified individuals that served on at least one editorial board between 2000 and 2020, there were 36 females (7.7%) and 430 males (92.3%). There were no significant differences between males and females serving on multiple editorial boards. Most females possessed an additional graduate degree (58.3%), while only one-third of males (33.5%) obtained such a degree (p = 0.002). In addition, males had significantly higher average H-indices than females (p = 0.002). These trends were also observed when analyzing only US-based editorial board members. Although females were more likely overall to be identified as associate professors, males were more likely to be appointed as full professors (p = 0.001); this trend did not remain true in the US-based cohort. When analyzing the editorial boards for individual journals, all 5 journals experienced an increase of female representation since 2000 or since their inception after 2000. The highest proportion of females for a single journal was 27.3% in 2020. All other journals ranged from 11.0% to 13.5% in 2020.
    CONCLUSIONS: When entering the field of neurosurgery, females continue to face significant social and academic barriers. While the proportion of females on editorial boards for neurosurgery journals in 2020 is consistent with the proportion of practicing female neurosurgeons, there is a statistically significantly higher likelihood that females possess additional graduate degrees and lower H-indices compared to their male counterparts. The authors encourage neurosurgical journals to continue expanding female representation on editorial boards.
    Keywords:  editorial board; females; gender composition; neurosurgical journals
    DOI:  https://doi.org/10.3171/2021.6.JNS21474
  22. Int J Environ Res Public Health. 2021 Oct 16. pii: 10875. [Epub ahead of print]18(20):
      Medical, health and wellness tourism and travel represent a dynamic and rapidly growing multi-disciplinary economic activity and field of knowledge. This research responds to earlier calls to integrate research on travel medicine and tourism. It critically reviews the literature published on these topics over a 50-year period (1970 to 2020) using CiteSpace software. Some 802 articles were gathered and analyzed from major databases including the Web of Science and Scopus. Markets (demand and behavior), destinations (development and promotion), and development environments (policies and impacts) emerged as the main three research themes in medical-health-wellness tourism. Medical-health-wellness tourism will integrate with other care sectors and become more embedded in policy-making related to sustainable development, especially with regards to quality of life initiatives. A future research agenda for medical-health-tourism is discussed.
    Keywords:  bibliometric analysis; medical-health-wellness tourism; research agenda; thematic analysis
    DOI:  https://doi.org/10.3390/ijerph182010875
  23. Entropy (Basel). 2021 Sep 30. pii: 1289. [Epub ahead of print]23(10):
      In recent years, supercritical CO2 power cycles have received a large amount of interest due to their exceptional theoretical conversion efficiency above 50%, which is leading a revolution in power cycle research. Furthermore, this high efficiency can be achieved at a moderate temperature level, thus suiting concentrating solar power (CSP) applications, which are seen as a core business within supercritical technologies. In this context, numerous studies have been published, creating the need for a thorough analysis to identify research areas of interest and the main researchers in the field. In this work, a bibliometric analysis of supercritical CO2 for CSP applications was undertaken considering all indexed publications within the Web of Science between 1990 and 2020. The main researchers and areas of interest were identified through network mapping and text mining techniques, thus providing the reader with an unbiased overview of sCO2 research activities. The results of the review were compared with the most recent research projects and programs on sCO2 for CSP applications. It was found that popular research areas in this topic are related to optimization and thermodynamics analysis, which reflects the significance of power cycle configuration and working conditions. Growing interest in medium temperature applications and the design of sCO2 heat exchangers was also identified through density visualization maps and confirmed by a review of research projects.
    Keywords:  CSP; bibliometric; concentrating solar power; power cycles; sCO2; scientometrics; solar energy; supercritical CO2; supercritical fluids
    DOI:  https://doi.org/10.3390/e23101289
  24. Pediatr Radiol. 2021 Oct 21.
       BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has heightened existing gender differences in academic productivity in medicine. There have been discrepant repercussions for women in academics due to the pandemic, including fewer publications, potentially impacting academic advancement.
    OBJECTIVE: To evaluate trends over time in the gender of authors of manuscripts submitted to Pediatric Radiology.
    MATERIALS AND METHODS: This retrospective review of unsolicited manuscripts submitted to Pediatric Radiology from January 2017 to December 2020 included only submissions from North America. For each submission, genders of the first, last (senior) and corresponding authors were inferred by inspection or confirmed by internet search. Chi-square and Fisher exact tests were used to compare authorship gender proportions. Quarterly comparisons between 2019 and 2020 were performed to assess for differences during the COVID-19 pandemic.
    RESULTS: Between 2017 and 2020, 1,018 manuscripts were submitted. There was no significant difference in female authorship over time (P > 0.05 for first, last and corresponding authors), but there was an increase in female first authorship (38.6% in 2017, 43.2% in 2020). The frequencies of female first (P = 0.03) and last (P = 0.01) authors were significantly higher for educational manuscripts (reviews and pictorial essays) versus other manuscript types. Manuscript submissions increased in the second quarter of 2020; however, there was a statistically significant decrease in last authorship by women during this period (P = 0.02).
    CONCLUSION: Female authorship of manuscripts submitted to Pediatric Radiology has remained relatively stable between 2017 and 2020. During the early phase (March-May 2020) of the COVID-19 pandemic, female last authorship was significantly lower versus the previous year.
    Keywords:  Authorship; COVID-19; Gender; Pediatric radiology; Publications
    DOI:  https://doi.org/10.1007/s00247-021-05213-6
  25. CRISPR J. 2021 Oct;4(5): 728-738
      Over the past two decades, the discovery of CRISPR-Cas immune systems and the repurposing of their effector nucleases as biotechnological tools have revolutionized genome editing. The corresponding work has been captured by 90,000 authors representing 7,600 affiliations in 126 countries, who have published more than 19,000 papers spanning medicine, agriculture, and biotechnology. Here, we use tech mining and an integrated bibliometric and networks framework to investigate the CRISPR literature over three time periods. The analysis identified seminal papers, leading authors, influential journals, and rising applications and topics interconnected through collaborative networks. A core set of foundational topics gave rise to diverging avenues of research and applications, reflecting a bona fide disruptive emerging technology. This analysis illustrates how bibliometrics can identify key factors, decipher rising trends, and untangle emerging applications and technologies that dynamically shape a morphing field, and provides insights into the trajectory of genome editing.
    DOI:  https://doi.org/10.1089/crispr.2021.0001
  26. JMIR Ment Health. 2021 Oct 14.
       BACKGROUND: The COVID-19 pandemic and its mitigation measures such as shelter-in-place orders, social isolation, restrictions on freedoms, unemployment, financial insecurity and disrupted routines, have led to declines in mental health worldwide and concomitant escalating demands for mental health services. Under the circumstances, e-mental health programs and services have rapidly become the "new normal".
    OBJECTIVE: To assess key characteristics and evidence gaps in the e-mental health literature published in relation to the COVID-19 pandemic via a scoping review and bibliometric analysis.
    METHODS: A search of four academic databases (MEDLINE, EMBASE, PsycINFO, CINAHL) published from 31st December 2019 to 31st March 2021 using keywords for e-mental health and COVID-19. Article information was extracted relevant to the review objective including journal, type of article, keywords, focus and corresponding author. Information was synthesised by coding these attributes, then summarised through descriptive statistics and narrative techniques. Article influence was examined from Altmetric and CiteScore data, and a network analysis was conducted on article keywords.
    RESULTS: A total of 356 publications were included in the review. Articles on e-mental health quickly thrived early in the pandemic, with most articles being non-empirical, chiefly commentaries or opinions (n = 225, 63.2%). Empirical publications emerged later and became more frequent as the pandemic progressed. The United States contributed the most articles (n = 160, 44.9%), though a notable number came from middle-income countries (n = 59, 16.6). Articles were spread across 165 journals, and were of above-average-influence (almost half of the articles were in the top 25% of outputs scores by Altmetric and the average CiteScore across articles was 4.22). The network analysis of author-supplied keywords identified key topic areas, including specific: mental disorders; e-health modalities; issues and challenges; and populations of interest. These were further explored via full-text analysis. Applications of e-mental health during the pandemic overcame, or were influenced by system, service, technology, provider and patient factors.
    CONCLUSIONS: COVID-19 has accelerated applications of e-mental health. Further research is needed to support the implementation of e-mental health across system and service infrastructure alongside evidence of the relative effectiveness of e-mental health in comparison to traditional modes of care.
    CLINICALTRIAL:
    DOI:  https://doi.org/10.2196/32948
  27. J Can Chiropr Assoc. 2021 Aug;65(2): 219-228
       Objectives: A bibliometric survey was conducted, using network and textual analysis tools, to assess the current state of the research enterprise at Canadian Memorial Chiropractic College and to augment planning processes.
    Methods: Searches were conducted via several databases to identify publications attributable to the institution. Bibliometric data were summarized and post-processed using the programme VosViewer and analysis tools provided in the Web of Science.
    Results: Canadian Memorial Chiropractic College is a productive source of peer-reviewed publications supported by a diverse suite of funding agencies and collaborating institutions, and published across a broad range of journals.
    Conclusions: As a private, single-purpose educational institution, awarding a qualification only in chiropractic, Canadian Memorial Chiropractic College probably performs well in its class of institution in terms of research productivity. However, assessment is constrained by inconsistencies on the part of authors, journals and databases in archiving data.
    Keywords:  MOTS CLÉS: chiropratique; chiropractic; recherche; research
  28. J Forensic Sci. 2021 Oct 22.
      Prior research evaluating the papers presented in forensic sciences in international meetings is scant. This study determines the possible predictions concerning publications by comparing the publication rates, publication years, and presentation types, time until publication, participating countries, and criteria of the published journals in the American Academy of Forensic Sciences (AAFS). The publication rates of abstracts presented at scientific meetings of AAFS, a prestigious forensic science organization, along with the aforementioned components and the extent of their contribution in 2011 and 2016 were investigated. The abstracts presented at the AAFS meetings in 2011 and 2016 were reviewed retrospectively within the scope of this study. The Web of Science, PubMed, Scopus, Science Direct, and Google Scholar databases were searched using a specified process that included the title, first and last author surnames, and keywords. Results revealed that approximately 21% and 24% of the papers presented at the 2011 and 2016 AAFS meetings, respectively, were published. Considering the publication rates of abstracts according to sections, the publication rates for the 2011 AAFS meeting ranged from 4% (questioned documents) to 31% (anthropology) and from 5% (questioned documents) to 32% (pathology/biology), on average, for the 2016 AAFS meeting. It was determined that the papers were largely published in the Journal of Forensic Sciences for both annual scientific meetings. Future studies should concentrate on the obstacles to the publication of papers presented at such prestigious organizations and strategies to facilitate the publication process such that they do not lose their value over time.
    Keywords:  American Academy of Forensic Sciences; abstracts; bibliometry; forensic sciences; meetings; publication ratio
    DOI:  https://doi.org/10.1111/1556-4029.14904
  29. Am J Obstet Gynecol MFM. 2021 Oct 14. pii: S2589-9333(21)00204-4. [Epub ahead of print] 100509
       BACKGROUND: There has been an increasing number of randomized controlled trials (RCTs) published in obstetrics and maternal-fetal medicine to reduces biases of treatment effect and to provide insights on cause-effect of relationship between treatment and outcomes.
    OBJECTIVES: To identify obstetrical RCTs published in top weekly general medical journals and monthly obstetrics and gynecology (OBGYN) journals, to assess their quality in reporting and to identify factors associated with publication in different journals.
    METHODS: The four weekly medical journals with the highest 2019 impact factor (New England Journal of Medicine, The Lancet, JAMA and the British Medical Journal), the top four monthly OBGYN journals with obstetrics related research (American Journal of Obstetrics and Gynecology, Ultrasound in Obstetrics and Gynecology, Obstetrics & Gynecology, The British Journal of Obstetrics and Gynaecology) as well as American Journal of Obstetrics and Gynecology MFM were searched for obstetrical RCTs in the years 2018-2020. The primary outcome was the number of obstetrical RCTs published in the OBGYN journals versus the weekly medical journals, as well as the percentage of trials published, overall and per journal. Secondary outcomes included the proportion of positive versus negative trials overall and per journal and the assessment of the study characteristics of published trials including quality assessment criteria.
    RESULTS: Of the 4,024 original research articles published in the 9 journals during the 3-year study period, 1,221 (30.3%) were RCTs, with 137 RCTs (11.2%) being in obstetrics (46 in 2018, 47 in 2019 and 44 studies in 2020). Thirty-three (24.1%) were published in weekly medical journals and 104 (75.9%) were published in OBGYN journals. The percentage of obstetrical RCTs published ranged from 1.5% to 9.6% per journal. Overall, 34.3% of obstetrical trials were statistically significant or 'positive' for the primary outcome. 24.8% of the trials were retrospectively registered after the enrollment of the first study patient. Trials published in the four weekly medical journals enrolled significantly more patients (1,801 vs 180, p<0.001), received more often funding from the federal government (78.8% vs 35.6%, p<0.001) and were more likely to be multicenter (90.9% vs 42.3%, p<0.001), non-US based (69.7% vs 49.0%, p=0.03) and double-blinded (45.5% vs 18.3%, p=0.003) when compared to the trials published in the OBGYN journals. There was no difference in study type (non-inferiority versus superiority) and trial quality characteristics including pretrial registration, ethics approval statement, informed consent statement and adherence to CONSORT guidelines statement between studies published in weekly medical and OBGYN journals.
    CONCLUSION: Approximately 45 trials in obstetrics and being are published every year in the highest impact journals, with one fourth being in the weekly medical journals and the remainder in the OBGYN journals. Only about a third of published obstetrical trials are positive. Trials published in weekly medical journals are larger, more likely to be funded by the government, multicenter, international, and double blinded. Quality metrics are similar between weekly medical and OBGYN journals.
    Keywords:  impact factor; maternal-fetal medicine; obstetrics; randomized controlled trials
    DOI:  https://doi.org/10.1016/j.ajogmf.2021.100509
  30. Trauma Violence Abuse. 2021 Oct 21. 15248380211050562
      China has made remarkable progress in preventing and intervening in domestic violence against women. Scholars have reported on this development. Methodologically, this paper, which draws on 3362 references selected from the China National Knowledge Infrastructure, uses the bibliometric method to summarize the characteristics, evolution, and frontiers of key topics into research on abused women in China between 1993 and 2020. The paper has three key findings. (1) The volume of literature has grown continuously, but in three stages: initial, rapid growth, and peak fluctuation; (2) the topic has five research hotspots: fundamental issues in domestic violence against women; new legislation, notably the 2015 Anti-Domestic Violence Law; social support for abused women; matrimonial disputes involving abused women; and conviction and sentencing of abused women who kill their husbands; and (3) the current research frontiers lie within the defects of the Anti-Domestic Violence Law and challenges in the implementation of the law. In addition, the paper examines characteristics and limitations of the study on abused women in China and suggests changes in practice, policy, and directions for future research.
    Keywords:  Abused women; China; CiteSpace; domestic violence; laws
    DOI:  https://doi.org/10.1177/15248380211050562
  31. BMJ Glob Health. 2021 Oct;pii: e006672. [Epub ahead of print]6(10):
       BACKGROUND: Global surgery has recently gained prominence as an academic discipline within global health. Authorship inequity has been a consistent feature of global health publications, with over-representation of authors from high-income countries (HICs), and disenfranchisement of researchers from low-income and middle-income countries (LMICs). In this study, we investigated authorship demographics within recently published global surgery literature.
    METHODS: We performed a systematic analysis of author characteristics, including gender, seniority and institutional affiliation, for global surgery studies published between 2016 and 2020 and indexed in the PubMed database. We compared the distribution of author gender and seniority across studies related to different topics; between authors affiliated with HICs and LMICs; and across studies with different authorship networks.
    RESULTS: 1240 articles were included for analysis. Most authors were male (60%), affiliated only with HICs (51%) and of high seniority (55% were fully qualified specialist or generalist clinicians, Principal Investigators, or in senior leadership or management roles). The proportion of male authors increased with increasing seniority for last and middle authors. Studies related to Obstetrics and Gynaecology had similar numbers of male and female authors, whereas there were more male authors in studies related to surgery (69% male) and Anaesthesia and Critical care (65% male). Compared with HIC authors, LMIC authors had a lower proportion of female authors at every seniority grade. This gender gap among LMIC middle authors was reduced in studies where all authors were affiliated only with LMICs.
    CONCLUSION: Authorship disparities are evident within global surgery academia. Remedial actions to address the lack of authorship opportunities for LMIC authors and female authors are required.
    Keywords:  health services research; obstetrics; other study design; surgery
    DOI:  https://doi.org/10.1136/bmjgh-2021-006672
  32. Am J Prev Med. 2021 Oct 14. pii: S0749-3797(21)00457-8. [Epub ahead of print]
       INTRODUCTION: The U.S. Preventive Services Task Force (USPSTF) issues "Insufficient Evidence" (I) statements when scientific evidence is inadequate for making recommendations about clinical preventive services. Insufficient Evidence statements may be changed to definitive recommendations if new research closes evidence gaps. This study examines the characteristics of evidence that informed changes from I statements to definitive recommendations, including NIH's role as a funder.
    METHODS: A total of 11 USPSTF Insufficient Evidence statements that were changed between 2010 and 2019 were assessed. Study designs, bibliometric influence, and funding sources for scientific articles cited in USPSTF evidence reviews were characterized for each I statement. Data were analyzed in 2019-2020.
    RESULTS: Most I statements (82%) changed to a B grade; an average of 8.4 years elapsed between issuing the I statement and releasing the definitive recommendation. An average of 63 (range=19-253) articles were included in each USPSTF evidence review. NIH support was cited in 28.8% of articles, on average. The proportion of NIH-funded articles reporting RCT designs was similar to that of non-NIH-funded articles (64.5% vs 59.5%). A higher proportion of NIH-funded articles were rated good quality for study design (39.0%) than the proportion of non-NIH-funded articles (24.4%). Bibliometric influence measured by relative citation ratios was higher for NIH-funded (mean=14.78) than for non-NIH-funded (mean=5.07) articles.
    CONCLUSIONS: Study designs and funding supports varied widely across topics, but overall, NIH was the largest single funder of evidence informing 11 changed USPSTF I statements. Enhanced efforts by NIH and other stakeholders to address I statement evidence gaps are needed.
    DOI:  https://doi.org/10.1016/j.amepre.2021.07.014
  33. Foods. 2021 Oct 06. pii: 2373. [Epub ahead of print]10(10):
      Waste management is one of the great problems in the world today. This study aims to analyse how scientific research has evolved in recent years in the field of waste management and what will be the key issues in the coming years, mainly in terms of recovery. The methodology used was longitudinal bibliometric analysis through scientific mapping using strategic maps and thematic networks. Among the findings, it was confirmed that the concept of incineration is fading due to social opposition and is changing to a much broader concept that encompasses it, such as valorisation. Being able to create a circular economy without waste should be the goal of policy makers. To achieve this, the waste hierarchy must be respected, which indicates that waste must be managed in this order: prevention, minimisation, reuse, valorisation, recovery and elimination.
    Keywords:  SciMAT; bibliometric analysis; incineration; municipal solid waste; valorisation; waste-to-energy
    DOI:  https://doi.org/10.3390/foods10102373
  34. Scientometrics. 2021 Oct 12. 1-21
      Bibliometric analyses of systematic reviews offer unique opportunities to explore the character of specific scientific fields. In this time series-based analysis, dynamics of multidisciplinary care for chronic pain and opioid prescribing are analyzed over a forty-four year time span. Three distinct periods are identified, each defined by distinct research areas, as well as priorities regarding the use of opioids and the appropriate management of chronic pain. These scientometrically defined periods align with timelines identified previously by narrative historical accounts. Through cross-correlation with a mortality time series, a significant two-year lag between opioid overdose mortality and citation dynamics is identified between 2004 and 2019. This analysis demonstrates a bidirectional relationship between the scientific literature and the North American opioid overdose crisis, suggesting that the scientific literature is both reflective and generative of an important health and social phenomenon. A scientometric phenomenon of memory lapse, namely an overt and prolonged failure to cite older relevant literature, is identified using a metric of mean time to citation. It is proposed that this metric can be used to analyze changes in emerging literature and thus predict the nature of clinical and policy responses to the opioid crisis, and thus potentially to other health and social phenomena.
    Keywords:  Bibliometrics; Multidisciplinary; Opioid; Systematic review; Time series
    DOI:  https://doi.org/10.1007/s11192-021-04154-z
  35. Neuropsychopharmacol Rep. 2021 Oct 22.
       AIM: Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique that shows potential for treating psychiatric disorders. Although several studies have sought to investigate new TMS modalities for the treatment of various psychiatric disorders, no study has yet examined publication trends in research on TMS modalities for psychiatric disorders. This study investigated publication trends in TMS research for 13 psychiatric disorders, including addiction, dementia, major depressive disorder (MDD), and obsessive-compulsive disorder (OCD), and schizophrenia, as well as 9 TMS modalities, including bilateral stimulation, deep TMS, high-frequency stimulation, low-frequency stimulation, and theta burst stimulation.
    METHODS: Articles published in PubMed from 1985 to 2019 were searched to determine the number of published articles for each year in each category using the "Results by year" tool from the PubMed database.
    RESULTS: Over the past 30 years, an increasing number of articles were published regarding TMS research for the treatment of MDD, addiction, and dementia, which were among those most commonly investigated psychiatric disorders, whereas the number of articles addressing schizophrenia and OCD treated via TMS remained steady since 2015. Regarding TMS modalities, previous high-frequency stimulation, low-frequency stimulation, and bilateral stimulation were the most common topics, with research regarding deep TMS and theta burst stimulation having increased since 2000 and 2005, respectively.
    CONCLUSION: TMS applications are rapidly developing and becoming increasingly ubiquitous in various psychiatric disorders. Determining publication trends in TMS research can be a useful method for monitoring TMS research interests and applications of new TMS modalities for psychiatric disorders.
    Keywords:  major depressive disorder; psychiatric disorder; research publication trends; transcranial magnetic stimulation; transcranial magnetic stimulation modality
    DOI:  https://doi.org/10.1002/npr2.12212
  36. Scientometrics. 2021 Oct 12. 1-23
      Altmetric indicators allow exploring and profiling individuals who discuss and share scientific literature in social media. But it is still a challenge to identify and characterize communities based on the research topics in which they are interested as social and geographic proximity also influence interactions. This paper proposes a new method which profiles social media users based on their interest on research topics using altmetric data. Social media users are clustered based on the topics related to the research publications they share in social media. This allows removing linkages which respond to social or personal proximity and identifying disconnected users who may have similar research interests. We test this method for users tweeting publications from the fields of Information Science & Library Science, and Microbiology. We conclude by discussing the potential application of this method and how it can assist information professionals, policy managers and academics to understand and identify the main actors discussing research literature in social media.
    Keywords:  Altmetrics; Information science and library Science; Microbiology; Network analysis; Socio-semantic networks; Twitter
    DOI:  https://doi.org/10.1007/s11192-021-04167-8
  37. ATS Sch. 2021 Sep;2(3): 415-431
      Background: The National Institutes of Health (NIH) Loan Repayment Programs (LRPs) were established by Congress in 2000 to help attract and retain highly qualified health professionals in biomedical careers by relieving financial pressure incurred from educational loans obtained during medical school and other advanced-degree clinical training programs. In 2019, the NIH LRP Program increased the maximum repayment from $35,000 per year to $50,000 per year for an individual's educational debt in return for two years of research performed in an NIH mission-relevant area (https://www.lrp.nih.gov/eligibility-programs). In addition, in 2020, the National Heart, Lung, and Blood Institute (NHLBI) increased its participation in the LRP by adding the Health Disparities Research Program to Clinical Research and Pediatric Research Programs. Objective: Before these substantive changes took effect, we sought to determine the impact of the NHLBI's participation in the LRP program on retention of scientists in the biomedical research workforce over the past 20 years. Methods: NHLBI LRP applicant cohorts from 2003 and 2008 were carefully examined with a 10-year follow-up period to measure the impact of applying for and obtaining NIH LRP funding on subsequent K- and R-level application and award rates, publication number, and average relative citation ratio as metrics to assess recruitment and retention of scientists in the biomedical research workforce. Results: Obtaining the LRP award was strongly associated with increased submission of and success in obtaining K- and RPG-grant funding and publications for both the 2003 and 2008 NHLBI LRP cohorts. An analysis of subgroups in the 2008 LRP cohort without prior F, K, or RPG funding revealed a consistently strong association between obtaining an LRP award and subsequent K- or RPG-award submission and success as well as potential synergy between obtaining an LRP award and participation on a T grant toward subsequent K- or RPG-award success rates. Conclusion: The LRP award appears to enhance retention in the biomedical research workforce when measured using metrics of grant application and award rates as well as research publications over a 10-year period.
    Keywords:  Loan Repayment Program; NHLBI; NIH; biomedical workforce; clinician scientists
    DOI:  https://doi.org/10.34197/ats-scholar.2020-0158OC
  38. Braz J Med Biol Res. 2021 ;pii: S0100-879X2021001200603. [Epub ahead of print]54(12): e11728
      A close interaction between basic science and applied medicine is to be expected. Therefore, it is important to measure how far apart the field of cell biology and medicine are. Our approach to estimating the distance between these fields was to compare their vocabularies and to quantify the difference in word repertoire. We compared the vocabulary of the title and abstract of articles available in PubMed in two selected high-impact journals in each field: cell biology, medicine, and translational science. Although each journal has its own editorial policy, we showed that within each field there is a small vocabulary difference between the two journals. We developed a word similarity index that can measure how much journals share a common vocabulary. We found a high similarity index between each cell biology (91%), medical (71-74%), and translational journal (65%). In contrast, the comparison between medicine and biology journals produced low correlation values (22-36%), suggesting that their vocabularies are quite dissimilar. Translational medicine journals had medium similarity values when compared to cell biology journals (52-70%) and medicine journals (27-59%). This approach was also performed in 10-year periods to evaluate the evolution of each field. Using the "onomics" strategy presented here, we observed that differences in vocabulary of basic science and medicine have been increasing over time. Since translational medicine has an intermediate vocabulary, we confirmed that translational medicine is an efficient approach to bridge this gap.
    DOI:  https://doi.org/10.1590/1414-431X2021e11728
  39. Neurology. 2021 Oct 20. pii: 10.1212/WNL.0000000000012867. [Epub ahead of print]
       OBJECTIVE: To determine if maintaining continuity in research topic and method from early to late career yields a greater likelihood of physician-scientists' research-career success i.e. achieving research independence and producing impactful publications.
    METHODS: To explore the impact of maintaining continuity in research, 108 2000-2010 neurology residency graduates from former Medical Scientist Training Programs at the highest NINDS and NIH funded institutions were identified. Through comparison of Ph.D. dissertations with post-graduate work, research continuity was deemed present if there was evidence of continuity in research topic and method. With publicly available SCOPUS, PubMed, and NIH RePORT data, the correlation that degree of continuity had with h-indices, number of grants awarded, and R01 acquisition was examined.
    RESULTS: Nearly half of the graduates were classified as non-continuous (45%), less than a quarter classified as somewhat continuous (22%), and roughly a third classified as very continuous (32%). The data demonstrated that research continuity increased the ability to acquire a R01, with 83% percent of R01 and/or R21 recipients having very continuous research. Very continuous graduates also had higher median number of grants received (2 [IQR: 1-3]) and a higher median h-index (17 [IQR: 10.5-20]) compared to the somewhat continuous and non-continuous groups.
    CONCLUSIONS: This study highlights research continuity as an important and modifiable variable during the training period of physician-scientists and one that may improve their career success and promote greater retention within the workforce.
    DOI:  https://doi.org/10.1212/WNL.0000000000012867
  40. Environ Sci Pollut Res Int. 2021 Oct 19.
      Occupational exposure to pesticides has been identified as a major trigger of the development of cancer. Pesticides can cause intoxication in the individuals who manipulate them through either inhalation, ingestion, or dermal contact. Given this, we investigated the association between the incidence of cancer and occupational exposure to pesticides through a bibliometric analysis of the studies published between 2011 and 2020, based on 62 papers selected from the Scopus database. The results indicated an exponential increase in the number of studies published over the past decade, with most of the research being conducted in the USA, France, India, and Brazil, although a further 17 nations were also involved in the research on the association between cancer and pesticides. The principal classes of pesticides investigated in relation to their role in intoxication and cancer were insecticides, herbicides, and fungicides. The types of cancer reported most frequently were multiple myeloma, bladder cancer, non-Hodgkin's lymphoma, prostate cancer, leukemia, and breast cancer. Despite the known association between pesticides and cancer, studies are still relatively scarce in comparison with the global scale of the use of these xenobiotic substances, which is related to the increasing demand for agricultural products throughout the world.
    Keywords:  Agriculture; Cancer; DNA; Diseases; Farm workers; Health; Pesticides
    DOI:  https://doi.org/10.1007/s11356-021-17031-2
  41. J Clin Epidemiol. 2021 Oct 15. pii: S0895-4356(21)00331-0. [Epub ahead of print]
       OBJECTIVES: To examine the characteristics, methodological and reporting quality of systematic reviews and meta-analyses in social science journals in China.
    STUDY DESIGN AND SETTING: The Chinese Social Sciences Citation Index (CSSCI) databases were searched for systematic reviews and meta-analysis published between January 2000 and December 2019. We randomly selected 200 articles from the 401 identified in our search. The Assessing the Methodological Quality of Systematic Reviews (AMSTAR) and the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) checklists were used to assess the methodological and reporting quality, respectively.
    RESULTS: The 200 articles we selected covered a wide range of research fields in 9 disciplines, most of which belonged to management, education and psychology. The mean AMSTAR score and PRISMA score was 8.99±3.36 points and 14.74±3.96 points, respectively. These findings indicated that the quality of the systematic reviews was below the average level. Meanwhile, year of publication was related to both methodological quality (p=0.001) and reporting quality (p<0.01).
    CONCLUSIONS: Although many systematic reviews and meta-analysis have been published in top Chinese journals, the methodological and reporting quality is troubling. Thus, the most urgent task is to increase the standard of systematic reviews and meta-analysis of every discipline rather than continuing to publish them in great quantity.
    Keywords:  Methodological quality; Reporting quality; Social Science; Systematic review/Meta-analysis
    DOI:  https://doi.org/10.1016/j.jclinepi.2021.09.031
  42. Clin Implant Dent Relat Res. 2021 Oct 20.
       BACKGROUND AND PURPOSE: Significant research and development (R&D) has been conducted to make the best dental implants while developing various patent applications and registrations. In this study, we evaluated the current status of patents on dental implants and identified the future direction of R&D progress.
    MATERIALS AND METHODS: A total of 29 711 patents related to dental implants were reviewed. These were published between 1909 and 2020 and retrieved from the Derwent Innovation patent database. The patents were grouped into three categories depending on the implant components: fixture, abutment, and artificial teeth.
    RESULTS: The category with most patents was "abutment," and the most cited patent was "screw-type dental implant anchor." Global patenting trends over the past 20 years showed that both applicants and applications increased in the early 2010s; however, these have since been on the decline. Currently, the United States holds the largest number of patents, and Nobel Biocare Holding AG is the top assignee. Technic maturation prediction analysis showed that the current dental implant technology is in the "decline stage."
    CONCLUSION: Trend analysis of the dental implant patent indicates the main contributors of development are profit-oriented companies. Recent reduction in the number of new patent applications suggests the technology is in the mature declining stage. The emergence of new materials or technologies that may close the gap in clinical unmet needs would reverse the trend.
    Keywords:  dental implant; development; patent; research; technology
    DOI:  https://doi.org/10.1111/cid.13048
  43. PLoS One. 2021 ;16(10): e0257919
      During the early months of the COVID-19 pandemic, there was an unusually high submission rate of scholarly articles. Given that most academics were forced to work from home, the competing demands for familial duties may have penalized the scientific productivity of women. To test this hypothesis, we looked at submitted manuscripts and peer review activities for all Elsevier journals between February and May 2018-2020, including data on over 5 million authors and referees. Results showed that during the first wave of the pandemic, women submitted proportionally fewer manuscripts than men. This deficit was especially pronounced among more junior cohorts of women academics. The rate of the peer-review invitation acceptance showed a less pronounced gender pattern with women taking on a greater service responsibility for journals, except for health & medicine, the field where the impact of COVID-19 research has been more prominent. Our findings suggest that the first wave of the pandemic has created potentially cumulative advantages for men.
    DOI:  https://doi.org/10.1371/journal.pone.0257919
  44. J Pediatr Surg. 2021 Sep 20. pii: S0022-3468(21)00632-1. [Epub ahead of print]
       BACKGROUND/PURPOSE: Improvements in patient care are directly affected by scientific discovery, and surgeons have historically played a vital role in this process. However, increasing clinical demands and incentivization for pure clinical productivity present challenges for promoting academic productivity. The objective of this work was to analyze the effects of adding an academic relative value unit (aRVU) scoring system to an existing work RVU (wRVU)-based incentivization plan on academic productivity in a Department of Pediatric Surgery.
    METHODS: Prior to 2012, incentive bonuses in our Department were mainly based on clinical wRVU activities. A weighted scoring system for 30 specific aRVUs was established in 2012. Incentivization for wRVUs vs. aRVUs was based on the clinical full-time equivalent (cFTE) of each faculty member. Academic activities incentivized included grant submissions/funding, peer reviewed publications, national presentations, Study Section participation, education and mentoring activities, receipt of research or teaching awards, initiation of Institutional Review Board (IRB) protocols, new academic society committee memberships/chairpersons, and patents. Academic progress was analyzed from 2012 to 2020.
    RESULTS: During the study period, annual external federal funding increased from $750,168 to $5,768,243 (7.7-fold increase); annual peer-reviewed publications increased from 24 to 140 (5.8-fold increase); annual national presentations accepted for oral/poster presentations nearly doubled; and faculty members and their trainees received 41 competitive research awards including 8 American Pediatric Surgical Association Awards, 9 American Academy of Pediatrics Section on Surgery Awards, and 3 American College of Surgeons Awards. During the same study period, wRVUs increased by 8%.
    CONCLUSIONS: Incentivization based on the addition of an aRVU system to a pre-existing wRVU system was associated with a significant increase in academic productivity, while still maintaining clinical productivity. Implementing an aRVU program is an important means of increasing academic productivity in Pediatric and other Surgery Departments.
    Keywords:  Academic; Clinical; Relative value units
    DOI:  https://doi.org/10.1016/j.jpedsurg.2021.09.013
  45. Cureus. 2021 Sep;13(9): e17740
      Introduction Benefits of increasing diversity in teams include the addition of different perspectives leading to increased innovation and creativity, faster problem solving, improved workforce morale, and reduced burnout leading to improved patient outcomes. This article reviewed the trend of gender and racial disparity in vascular neurology fellowship programs. Methods We retrospectively analyzed the data extracted from the Accreditation Council for Graduate Medical Education (ACGME)'s annual Data Resource Books from 2007 to 2019. ACGME cataloged gender as men and women and race/ethnicity was categorized as White/Non-Hispanic, Asian or Pacific Island, Hispanic, Black/Non-Hispanic, Native American/Alaskan, others, and unknown. Counts, proportions, relative, and absolute percentage changes were calculated to highlight trends in resident appointments over time and across the specialty of vascular neurology. Results The representation of females increased steadily; with a relative increase of 11.78% from the year 2007 to 2019. Race/ethnicity was reported starting from the year 2011. When averaged across the nine-year study period, 35% of the study sample was White (Non-Hispanic), followed by Asian/Pacific Islanders at 25%. The representation of Hispanics was 4.8%, Black/African Americans were 3%, Native Americans/ Alaskans were 0.23% and Others were 13% of the total study population. For 17.7% of the fellows, racial data were not known and was categorized as Unknown racial distribution. Conclusion Our study concludes that gender and racial disparity persists within the fellowship programs of vascular neurology. Effective strategies at individual, administrative, and national levels are needed to engage women and under-represented minorities in vascular neurology as a career choice.
    Keywords:  gender disparity; healthcare; racial disparity; under-represented minorities; vascular neurology
    DOI:  https://doi.org/10.7759/cureus.17740