bims-evares Biomed News
on Evaluation of research
Issue of 2021–06–27
forty-five papers selected by
Thomas Krichel, Open Library Society
  1. Bibliometric analysis and mapping knowledge domain of pterygium: 2000-2019.
  2. Publication Trends of Non-Obstetric Brachial Plexus Injury Research: A Bibliometric Analysis.
  3. A bibliometric analysis of the most-cited articles on craniospinal epidural hematoma.
  4. The top 100 highly cited articles on anterior cruciate ligament from 2000 to 2019: A bibliometric and visualized analysis.
  5. Mapping of colorectal cancer scientific landscape between South Africa and Brazil: a bibliometric analysis.
  6. Mapping the knowledge domain of the evolution of emergy theory: a bibliometric approach.
  7. Iranian researchers' contributions to research on COVID-19: A bibliometric analysis and visualization.
  8. Knowledge Domain and Emerging Trends in Ferroptosis Research: A Bibliometric and Knowledge-Map Analysis.
  9. A bibliometric analysis of the application of procalcitonin in patients in the intensive care unit.
  10. Tracing ovarian cancer research in Morocco: A bibliometric analysis.
  11. Influential Articles on Pediatric and Adolescent Anterior Cruciate Ligament Injuries: A Bibliometric Analysis.
  12. Coronary Heart Disease and Depression or Anxiety: A Bibliometric Analysis.
  13. Application of Discrete Choice Experiment in Health Care: A Bibliometric Analysis.
  14. An analysis of scientometric data and publication policies of rheumatology journals.
  15. Evolution of Telepsychiatry: Scientometric Analysis of Telepsychiatry Publications Between 1986 and 2019.
  16. Tanner Awards for the Most-Cited Articles of 2018.
  17. Trade credit research before and after the global financial crisis of 2008 - A bibliometric overview.
  18. [2. Impact Factor and Its Importance].
  19. What is the Return on Investment of Spine Society Research Grants?
  20. A Decade of CRISPR Gene Editing in China and Beyond: A Scientometric Landscape.
  21. Impact factor abandoned by Dutch university in hiring and promotion decisions.
  22. Current global research landscape on COVID-19 and depressive disorders: Bibliometric and visualization analysis.
  23. In-text citation's frequencies-based recommendations of relevant research papers.
  24. High-Impact Clinical Studies That Fomented New Developments in Anesthesia: History of Achievements, 1966-2015.
  25. Building new paths for responsible solid waste management.
  26. The Holman Research Pathway in Radiation Oncology: 2010 - 2019.
  27. Tracking and Mapping the Use of CRISPR-Cas Systems for Research in China.
  28. Academic studies on claimed past-life memories: A scoping review.
  29. Editors' choice: the most valued articles published in the European Journal of General Practice in 2020.
  30. Vignettes to Illustrate the Value of Tumor Biobanks in Cancer Research in Canada.
  31. Gaps, biases, and future directions in research on the impacts of anthropogenic land-use change on aquatic ecosystems: a topic-based bibliometric analysis.
  32. The case for incorporating literature citations and social media mentions in one citation index.
  33. Women are underrepresented in prestigious recognition awards in the American Urological Association.
  34. The Matilda Effect: Under-recognition of Women in Hematology and Oncology Awards.
  35. Characteristics, utilisation and influence of viewpoint articles from the Structured Operational Research and Training Initiative (SORT IT) - 2009-2020.
  36. Team Science: Defining and Achieving Success.
  37. The state of the scientific revolution in toxicology.
  38. Mapping the intellectual structure of the coronavirus field (2000-2020): a co-word analysis.
  39. United States Radiation Oncology Fellowship Growth from 2010-2020.
  40. Surgery and the kings of medical science : Invited Commentary: "Publication activity of chief and senior general/visceral surgeons in German university hospitals - a ten-year analysis", Böckmann et al.
  41. Female (Under) Representation in Exercise Thermoregulation Research.
  42. Speaking up for balance: analysis of the gender of invited speakers at UK dental conferences.
  43. Statistical methods and software used in nutrition and dietetics research: A review of the published literature using text mining.
  44. Visualizing risk factors of dementia from scholarly literature using knowledge maps and next-generation data models.
  45. The use of SNOMED CT, 2013-2020: a literature review.
  1. Int J Ophthalmol. 2021 ;14(6): 903-914
    Bibliometric analysis and mapping knowledge domain of pterygium: 2000-2019.
    Yu-Chi Wang, Fang-Kun Zhao, Qian Liu, Zi-Yan Yu, Jing Wang, Jin-Song Zhang.
       AIM: To track the knowledge structure, topics in focus, and trends in emerging research in pterygium in the past 20y.
    METHODS: Base on the Web of Science Core Collection (WoSCC), studies related to pterygium in the past 20y from 2000-2019 have been included. With the help of VOSviewer software, a knowledge map was constructed and the distribution of countries, institutions, journals, and authors in the field of pterygium noted. Meanwhile, using co-citation analysis of references and co-occurrence analysis of keywords, we identified basis and hotspots, thereby obtaining an overview of this field.
    RESULTS: The search retrieved 1516 publications from WoSCC on pterygium published between 2000 and 2019. In the past two decades, the annual number of publications is on the rise and fluctuated a little. Most productive institutions are from Singapore but the most prolific and active country is the United States. Journal Cornea published the most articles and Coroneo MT contributed the most publications on pterygium. From co-occurrence analysis, the keywords formed 3 clusters: 1) surgical therapeutic techniques and adjuvant of pterygium, 2) occurrence process and pathogenesis of pterygium, and 3) epidemiology, and etiology of pterygium formation. These three clusters were consistent with the clustering in co-citation analysis, in which Cluster 1 contained the most references (74 publications, 47.74%), Cluster 2 contained 53 publications, accounting for 34.19%, and Cluster 3 focused on epidemiology with 18.06% of total 155 co-citation publications.
    CONCLUSION: This study demonstrates that the research of pterygium is gradually attracting the attention of scholars and researchers. The interaction between authors, institutions, and countries is lack of. Even though, the research hotspot, distribution, and research status in pterygium in this study could provide valuable information for scholars and researchers.
    Keywords:  VOSviewer; bibliometric analysis; mapping knowledge domain; pterygium
    DOI:  https://doi.org/10.18240/ijo.2021.06.17
  2. World Neurosurg. 2021 Jun 21. pii: S1878-8750(21)00905-0. [Epub ahead of print]
    Publication Trends of Non-Obstetric Brachial Plexus Injury Research: A Bibliometric Analysis.
    Adilson Jose Manuel de Oliveira, Miguel Bertelli Ramos, Daniel Bohn, Mário Gilberto Siqueira, Eberval Gadelha Figueiredo.
       OBJECTIVE: To evaluate publication trends in non-obstetric brachial plexus injury research.
    METHODS: In September 2020, we searched Scopus for articles on non-obstretric brachial plexus injury. We retrieved their citation count, year of publication, country of the corresponding author and its income category, destiny journal and its 5-year impact factor (IF), and research type.
    RESULTS: A total of 1,245 articles were analyzed. The mean number of citations per article was 18.01 (95%CI=16.46-19.55). The mean IF was 3.60 (95%CI=3.25-3.95). The five most prolific journals had an IF<5, and the journal with the highest number of articles was the Journal of Hand Surgery: American Volume (5.6%;N=70). The most prolific country was the United States (25.1%;N=313). High-income countries represented 913 articles (73.3%), upper-middle income 246 (19.8%), and lower-middle income 68 (5.5%). No papers were from low-income countries. The representation of middle-income countries increased from 2.1% of published articles in the 1980-1989 period to 40.0% in the 2010-2019 period. Primary research represented 64.0% (N=797) of articles, while secondary research and case reports represented 13.0% (N=162) and 23.0% (N=286) of articles, respectively. Narrative reviews (11.4%;N=142) and systematic reviews (1.6%;N=20) comprised articles from the secondary research group.
    CONCLUSIONS: While high-income countries still represent the majority of publications, there is an increasing contribution of researchers from middle-income countries. The most common destiny journals are field-specific, with a relatively low IF. Although most articles were primary research, a representative portion had a shallow level of evidence (case reports and narrative reviews).
    Keywords:  accidents; bibliometrics; brachial plexus; paralysis; peripheral nerves; wounds and injuries
    DOI:  https://doi.org/10.1016/j.wneu.2021.06.074
  3. Turk Neurosurg. 2021 Jan 26.
    A bibliometric analysis of the most-cited articles on craniospinal epidural hematoma.
    Sarah Bin Abdulqader, Othman T Almutairi, Modhi A Alhussinan, Turki Elarjani, Abdullah Albathi, Abdulrahman Y Alturki, Mohammed Bafaquh.
       AIM: Epidural hematoma (EDH) is a commonly encountered neurosurgical condition. Numerous articles have been published on EDH. Bibliometric analysis studies the chronological trends and ranks the most impactful articles in a given field. The aim of this paper is to analyze the most-cited articles on cranial and spinal EDH.
    MATERIAL AND METHODS: A title-specific search was performed on the Scopus database using the term "epidural hematoma" in June 2020, with no publication date restrictions. The top 100 most-cited articles were collected, reviewed, and analyzed.
    RESULTS: A total of 2165 articles were published on EDH from 1949 to 2020, and the top 100 most-cited ones were published between 1966 and 2014, receiving an average citation of 84.7 per paper. Most papers were published in Neurosurgery and Journal of Neurosurgery (JNS). 48% of the most-cited articles on EDH originated from the United States of America (USA). Notably, studies on spinal EDH represented 75% of the most-cited articles in our review. The most-cited article on EDH was published by Lawton et al. in 1995, receiving a total of 412 citations at an annual citation rate of 16.4%.
    CONCLUSION: This report identifies the most influential publications on EDH as well as the publications trends over the last 70 years. Recognition of the most impactful work is an important tool for clinicians and researchers as it can reflect the enormous changes in the clinical practice. This report can serve as a guide for developing evidence-based practices and identifying areas of research inadequacy.
    DOI:  https://doi.org/10.5137/1019-5149.JTN.31889-20.3
  4. Orthop Traumatol Surg Res. 2021 Jun 16. pii: S1877-0568(21)00221-8. [Epub ahead of print] 102988
    The top 100 highly cited articles on anterior cruciate ligament from 2000 to 2019: A bibliometric and visualized analysis.
    Yuanliang Zhu, Chi Zhang, Jianxiong Wang, Yujie Xie, Wang Li, Xu Fangyuan.
       INTRODUCTION: Bibliometrics can trace the overall research trend in a specific field. To our knowledge, there has been no comprehensive bibliometric analysis of all anterior cruciate ligament (ACL) research from 2000-2019. We provided a bibliometric and visualized analysis of the top 100 highly-cited articles on ACL indexed by the Web of Science (WoS) to provide researchers with the present research status and the potential direction of ACL research.
    HYPOTHESIS: A bibliometric and visualized analysis of the top 100 highly-cited articles on ACL may identify the research trends, popular journals, core countries, influential institutions and authors in this field.
    MATERIAL AND METHODS: We obtained data from the WoS Core Collection on February 20, 2020. Qualitative and quantitative analyses were conducted based on the WoS. Collaboration and keywords analysis was performed using the VosView software.
    RESULTS: The top 100 highly-cited literatures included 88 articles and 12 reviews. The average total citations was 325 (ranging 197 to 1,423). The article with 1,432 citations published by Hewett TE et al. in 2005 was the most influential reference. Sixteen cohort studies and 14 clinical randomized controlled trials were included among the 100 literatures. Twenty-three journals published the top 100 literatures. The American Journal of Sports Medicine published 44 papers with 15,665 citations. The USA published 65 highly-cited articles. The University of Pittsburgh published 13 literatures with 3,966 citations. Hewett TE published 11 papers with 4,806 citations. Extensive collaboration existed worldwide. Reconstruction, kinematics, posterolateral bundle, in-situ forces, neuromuscular control, long-term follow-up, tunnel placement, and prevention were the most common keywords.
    DISCUSSION: In this field, The American Journal of Sports Medicine was the most influential journal. The USA was the most productive and influential country. Researchers and institutions from North America and Europe contributed the most. Regarding the treatments for ACL injuries, we do need well-reported and good-quality enduring randomized trials to assess the effectiveness and cost-effectiveness of current treatments. Level of proof: IV; retrospective analysis.
    Keywords:  ACL; bibliometric analysis; citation; influential
    DOI:  https://doi.org/10.1016/j.otsr.2021.102988
  5. Ecancermedicalscience. 2021 ;15 1216
    Mapping of colorectal cancer scientific landscape between South Africa and Brazil: a bibliometric analysis.
    Sphindile Magwaza, Guido Van Hal, Muhammad Hoque.
       Background: The five BRICS (Brazil, Russian, Indian, China and South Africa) countries bear a significant proportion of the world's global cancer burden.
    Aim: The aim of this paper is to map the scientific landscape related to colorectal cancer (CRC) research published related to South Africa (SA) and Brazil (BRA).
    Methods: We used the bibliometric analysis technique to identify and map the scientific publications on CRC related to SA and BRA. We identified the document type, authors, research organisations, countries, funding sources, most relevant journals, research areas, citation reference counts, journal impact factor (IF) and open access designations in CRC scientific landscape for both countries. We analysed publications from January 2000 to August 2020 as indexed in the Web of Science Core Collection, most covering scientific medical related research and used descriptive statistical data analysis to synthesise the data.
    Findings: During the period 2000-2020, there were 80 and 176 peer-reviewed publications on CRC related to SA and BRA, respectively. The majority were original research articles. Sixty-six percent identified had a primary (first) author affiliated to SA research institution and 87% had primary author affiliated to the BRA research institution. Overall, 275 authors published CRC related to SA and 1,025 authors published CRC related to BRA. The leading research organisation in SA was the University of Witwatersrand (Wits, 26%) and was the University of Sao Paulo (23%) for in BRA. The publications, related to both countries, mostly focused on oncology. The South African Medical Journal (10%) produced the most articles for SA with IF = 1.285; and the Value in Health (7%) for BRA with IF = 1.736. The median cited reference count was 32 for SA publications and 34 for BRA publications. There were 49% and 39% of publications without any open access designations for SA and BRA, respectively.
    Conclusions: Mapping CRC scientific publications highlighted potential benefits of developing an informed CRC national research plan in each country to promote concerted effort to better understand the risk factors, treatment and advocate for funding as stimulus for increased CRC research outputs that can inform policy development and influence practice to help reduce and control the CRC burden in both countries.
    Keywords:  Brazil; South Africa; bibliometrics; cancer; colorectal cancer; scientific landscape
    DOI:  https://doi.org/10.3332/ecancer.2021.1216
  6. Environ Sci Pollut Res Int. 2021 Jun 21.
    Mapping the knowledge domain of the evolution of emergy theory: a bibliometric approach.
    Xiumei Xu, Chao Feng.
      Bibliometric and visualization tools are effective for uncovering information contained in vast amounts of literature data. We retrieved publications from the Web of Science (2008-2020) and used the Statistical Analysis Toolkit for Informetrics (SATI) and CiteSpace to conduct a bibliometric analysis of emergy studies, review the focus of the studies, summarize current research, and identify academic trends. The SATI-based charts provided an overall description of yearly published articles, literature sources, high-frequency keywords, authors, institutions, and highly cited papers. CiteSpace was applied to determine the frontiers and hotspots of emergy theory. A dual-map analysis was used to reveal the connection between multiple disciplines. Keyword clustering analysis was performed to evaluate research hotspots. Moreover, burst analysis and timeline maps presented a holistic picture of cutting-edge issues and the evolutionary trajectory of emergy studies in recent years. An alluvial flow map analysis of the landmark literature depicted the transmission of knowledge in the emergy field. In addition, this article also evaluated the current status of collaborative research in emergy-related fields. The results can provide a reference for researchers to explore hot issues or target a specific field of study.
    Keywords:  Bibliometric; Emergy research; Knowledge domain map; Research hotspots; Theoretical evolution
    DOI:  https://doi.org/10.1007/s11356-021-14959-3
  7. Med J Islam Repub Iran. 2021 ;35 24
    Iranian researchers' contributions to research on COVID-19: A bibliometric analysis and visualization.
    Mohammad Karim Saberi, Arezoo Farhadi, Samira Karami, Heidar Mokhtari.
      Background: COVID-19 pandemic crisis motivated researchers worldwide to deeply investigate it from different perspectives. As Iran is one of the highly-affected countries by Covid-19, Iranian researchers have focused on studying it. This study aimed at analyzing and visualizing Iranian researchers' papers on COVID-19 from a bibliometric perspective. Methods: By searching MeSH-selected keywords related to COVID-19 in Scopus, Iranian researchers' papers on COVID-19 were extracted in a CSV format and underwent bibliometric techniques, such as coauthorship analysis, citation, and co-citation analysis, keyword and term co-occurrence mapping and etc. in the Microsoft Excel and VOSviewer software package. Results: A total of 405 papers were authored by Iranian researchers on COVID-19 during the study period, with the average number of citations per paper of 2.60 and a mean h-index of 15. The majority of papers were original articles in English. Archives of Clinical Infectious Diseases and Archives of Iranian Medicine and Medical Hypotheses were highly ranked publishing journals, respectively. The most productive institute and author were Tehran University of Medical Sciences with 119 papers and Rezaei, N. with 12 papers. Iranian researchers collaborated with the researchers of 73 countries, with the USA ranking first in Covid-19 research, followed by Italy, Canada, and United Kingdom. In publishing papers on COVID-19, Iran ranked first among the Middle Eastern countries and thirteenth internationally. Conclusion: Iranian researchers were active in 5 main areas of COVID-19 research, including epidemiology, diagnosis, treatment, virology, and systematic review.
    Keywords:  Bibliometrics; COVID-19; Data visualization; Iran; SARS-CoV-2
    DOI:  https://doi.org/10.47176/mjiri.35.24
  8. Front Oncol. 2021 ;11 686726
    Knowledge Domain and Emerging Trends in Ferroptosis Research: A Bibliometric and Knowledge-Map Analysis.
    Jie Zhang, Luxia Song, Liyan Xu, Yixuan Fan, Tong Wang, Wende Tian, Jianqing Ju, Hao Xu.
       Objectives: To identify the cooperation and impact of authors, countries, institutions, and journals, evaluate the knowledge base, find the hotspot trends, and detect the emerging topics regarding ferroptosis research.
    Methods: The articles and reviews related to ferroptosis were obtained from the Web of Science Core Collection on November 1, 2020. Two scientometric software (CiteSpace 5.7 and VOSviewer 1.6.15) were used to perform bibliometric and knowledge-map analysis.
    Results: A total of 1,267 papers were included, in 466 academic journals by 6,867 authors in 438 institutions from 61 countries/regions. The ferroptosis-related publications were increasing rapidly. Cell Death & Disease published the most papers on ferroptosis, while Cell was the top co-cited journal, publication journals and co-cited journals were major in the molecular and biology fields. The United States and China were the most productive countries; meanwhile, the University of Pittsburgh, Columbia University and Guangzhou Medical University were the most active institutions. Brent R Stockwell published the most papers, while Scott J Dixon had the most co-citations; simultaneously, active cooperation existed in ferroptosis researchers. Ten references on reviews, mechanisms, and diseases were regarded as the knowledge base. Five main aspects of ferroptosis research included regulation mechanisms, nervous system injury, cancer, relationships with other types of cell death, and lipid peroxidation. The latest hotspots were nanoparticle, cancer therapy, iron metabolism, and in-depth mechanism. Notably Nrf2 might have turning significance. The emerging topics on ferroptosis research were the further molecular mechanism of ferroptosis and the wider application of ferroptosis-related disease with advanced technology.
    Conclusion: This study performed a full overview of the ferroptosis research using bibliometric and visual methods. The information would provide helpful references for scholars focusing on ferroptosis.
    Keywords:  CiteSpace; VOSviewer; bibliometric; ferroptosis; knowledge-map
    DOI:  https://doi.org/10.3389/fonc.2021.686726
  9. Ann Palliat Med. 2021 Jun 21. pii: apm-21-895. [Epub ahead of print]
    A bibliometric analysis of the application of procalcitonin in patients in the intensive care unit.
    Yun Tan, Qingtan Yu, Lanxiang Ma, Jiang Chang, Xiujun Zhan, Haibin Cui, Ying Liu, Yongjie Sui.
       BACKGROUND: Patients in the intensive care unit (ICU) often have serious infections, and anti-infection treatment is vital for these patients. Procalcitonin (PCT) is often used to identify bacterial infections and monitor the effectiveness of anti-infection treatments. This study aims to analyze the current research hotspots of the application of PCT in ICU patients, and to suggest future research directions.
    METHODS: The Science Citation Index Expanded (SCI-EXPANDED) database in the Web of Science Core Collection (WOSCC) was used as the data source to search literature from 1995 to February 6, 2021. The search strategy was subject term = procalcitonin AND Web of Science categories = Critical Care Medicine. Using CiteSpace software, literature on the application of PCT in ICU patients was analyzed.
    RESULTS: A total of 1,243 papers, including 665 (53.5%) original articles, 87 (7.0%) reviews, 93 (7.5%) letters, 297 (23.9%) conference abstracts, and 101 (8.1%) other articles, were analyzed. The citation frequency was 40,442, the h-index was 96, and the average number of citations per item was 32.54. Research was mainly from the United States, Germany, France, and Spain, amongst others. The research institutions were mainly Univ Basel Hosp, Univ Pittsburgh, and Univ Hosp Geneva. Authors including Schuetz P made more contributions. Critical Care Medicine, Intensive Care Medicine, and Critical Care were important journals in this field of research. The keywords with the highest frequency were PCT, sepsis, and infection, and the more central ones were PCT, inflammation, septic shock, and C-reactive protein. The keywords with the strongest citation bursts were PCT, cytokine, and serum.
    CONCLUSIONS: Papers are mainly published in critical care medical journals. The countries, institutions, and authors that carry out research are relatively limited. The current hot spots are still inflammation, infection, and shock, especially the management and prognosis prediction of critically ill patients.
    Keywords:  Procalcitonin (PCT); bibliometric analysis; intensive care
    DOI:  https://doi.org/10.21037/apm-21-895
  10. Gynecol Oncol Rep. 2021 Aug;37 100777
    Tracing ovarian cancer research in Morocco: A bibliometric analysis.
    Khalid El Bairi, Ouissam Al Jarroudi, Said Afqir.
       Background: The burden of ovarian cancer (OC) in low-income countries continues to increase annually. This gynecological cancer, known for its poor survival outcomes, has not attracted much interest in medical research as compared to other women's malignancies such as breast cancer. This bibliometric study was conducted to better depict the global map and the future directions of scientific productivity in the area of OC research in Morocco.
    Methods: Publication trends on OC were retrospectively analyzed using a number of bibliometric parameters based on the Pubmed database and other resources.
    Results: During the time period (1900-2018), a total number of 74 publications responding to the inclusion criteria were found and incorporated in the bibliometric analysis. This was dominated by case reports and case series on rare ovarian tumors (n = 60). In the core cluster, only 10 original studies and 3 reviews on OC were published by Moroccan researchers. After full-text appraisal for study population, only two clinical original articles included OC patients. The other clinical studies included breast cancer patients only or were suggestive of inherited OC. In addition, 3 preclinical in vitro studies were found during the literature search. The majority of these publications were covered by Pubmed and Web of Science core collection and all published in English language. The H-index of top 10 Moroccan scientists in this area didn't exceed 10. Importantly, research and review articles were frequently published in influential journals. However, the number of publications as compared to other African countries was very low. Moreover, a similar trend in terms of article per each newly diagnosed OC case, GDP per capita and per million was also noticed. For gender distribution, female scientists were first authors in the majority of these papers but less represented as leading last authors. In the complementary cluster of other article types on rare ovarian tumors, 70% of the items were published in French and approximately 60% were indexed on Pubmed. During the last five years, a marked acceleration of publishing this research category with little impact in the evidence-based practice was noticed.
    Conclusions: This research area in gynecologic oncology seems to be neglected and needs to be prioritized in future research projects in Morocco particularly given the aggressive behavior of this women's cancer and the few available therapeutic options. There is an unmet need for studies on OC in all fields particularly epidemiology, clinic-pathological characteristics, and survival outcomes.
    Keywords:  BRCA, Breast cancer susceptibility gene; Bibliometric; Cancer research; GDP, gross domestic product; IARC, International Agency for Research on Cancer; Morocco; OC, ovarian cancer; OCAC, The Ovarian Cancer Association Consortium; Ovarian cancer; Scientometric; US, United States; WoS, Web of Science
    DOI:  https://doi.org/10.1016/j.gore.2021.100777
  11. Orthop J Sports Med. 2021 Jun;9(6): 23259671211010772
    Influential Articles on Pediatric and Adolescent Anterior Cruciate Ligament Injuries: A Bibliometric Analysis.
    Sachin Allahabadi, Sonali E Feeley, Drew A Lansdown, Nirav K Pandya, Brian T Feeley.
       Background: The understanding of pediatric anterior cruciate ligament (ACL) injuries and optimal treatment has evolved significantly. Influential articles have been previously evaluated using article citations to determine impact.
    Purpose: To identify and characterize the 50 most cited and recent influential articles relating to pediatric and adolescent ACL injuries, to examine trends in publication characteristics, and to evaluate correlations of study citations with quality of evidence.
    Study Design: Cross-sectional study.
    Methods: The top 50 most cited articles on pediatric and adolescent ACL injuries were gathered using the Web of Science and Scopus online databases by averaging the number of citations from each database. Articles from recent years were also aggregated and sorted by citation density (citations/year). Publication and study characteristics were recorded. Level of evidence and methodologic quality were assessed where applicable using the modified Coleman Methodology Score (mCMS), modified Jadad scale, and Methodological Index for Non-Randomized Studies (MINORS). Spearman correlation was used to evaluate the association between citation data and level of evidence or methodologic quality scorings.
    Results: The top 50 cited papers had a mean of 117.5 ± 58.8 citations (range, 58.5-288.5 citations), with a mean citation density of 9.4 ± 5.4 citations per year (range, 2.9-25.8 citations/year); 80% were published in 2000 or later, and 6% were considered basic science. Articles were mainly level 4 evidence (27/42; 64.3%), and none was level 1. There were moderate, significant associations between publication year and level of evidence (r S = -0.45; P = .0030) and citation density and publication year (r S = 0.59; P < .001). Mean methodologic quality scores were as follows: mCMS, 53 ± 7.2 (range, 39-68); modified Jadad scale, 3.2 ± 1.1 (range, 2-6); and MINORS, 11.2 ± 3.2 (range, 6-20). There was a significant, strong correlation between rank of mean citations and modified Jadad scale (r S = 0.76; P < .0001), suggesting poorer score associated with more mean citations.
    Conclusion: Influential articles on pediatric and adolescent ACL injuries were relatively recent, with a low proportion of basic science-type articles. Most of the studies had a lower evidence level and poor methodologic quality scores. Higher methodologic quality did not correlate positively with citation data.
    Keywords:  adolescent; anterior cruciate ligament; influential; pediatric sports medicine; quality; skeletally immature
    DOI:  https://doi.org/10.1177/23259671211010772
  12. Front Psychol. 2021 ;12 669000
    Coronary Heart Disease and Depression or Anxiety: A Bibliometric Analysis.
    Yan Zhou, Xue-Ping Zhu, Jing-Jing Shi, Guo-Zhen Yuan, Zi-Ang Yao, Yu-Guang Chu, Shuai Shi, Qiu-Lei Jia, Ting Chen, Yuan-Hui Hu.
      This study aimed to conduct a bibliometric analysis of published studies on the association between coronary heart disease (CHD) and depression or anxiety. The study also aimed to identify leading authors, institutions, and countries to determine research hotspots and obtain some hints from the speculated future frontiers. Publications about CHD and depression or anxiety between 2004 and 2020 were collected from the Web of Science Core Collection (WOSCC) database. Bibliographic information, such as authorship, country, citation frequency, and interactive visualization, was generated using VOSviewer1.6.16 and CiteSpace5.6.R5. In total, 8,073 articles were identified in the WOSCC database. The United States (2,953 publications), Duke University and Harvard University (214 publications), Psychosomatic Medicine (297 publications), and Denollet Johan. (99 publications) were the most productive country, institutions, journal, and author, respectively. The three hotspots of the research were "The relationship between depression and CHD," "depression and myocardial infarction," and "The characteristic of women suffering depression after MI." The four future research frontiers are predicted to be "treating depression in CHD patients with multimorbidity," "psychometric properties of instruments for assessing depression and anxiety in CHD patients," "depression or anxiety in post-PCI patients," and "other mental diseases in CHD patients." Bibliometric analysis of the association between CHD and depressive disorders might identify new directions for future research.
    Keywords:  CiteSpace; anxiety; bibliometric analysis; coronary heart disease; depression
    DOI:  https://doi.org/10.3389/fpsyg.2021.669000
  13. Front Public Health. 2021 ;9 673698
    Application of Discrete Choice Experiment in Health Care: A Bibliometric Analysis.
    Yue Wang, Zhangyi Wang, Zhao Wang, Xuechun Li, Xiaoli Pang, Shuling Wang.
      Background: Discrete choice experiment (DCE) as a tool that can measure medical stakeholders' preferences especially patients recently has been increasingly applied in health care. Objective: The aim of this study was to examine the hotspots and trends of the application of DCE in health care and to provide reference and direction for further development of DCE in the future. Method: A bibliometric method was implemented using the Web of Science (WoS) Core Collection for the period from the database established to December 8, 2020. The data files are imported into CiteSpace and Excel to analyze and visualize the annual volume of productive, authors, countries, cited journals, cited articles, and keywords. Results: A total of 1,811 articles were retrieved, then we read the abstract of each paper one by one, and 1,562 articles were included after screening, with an exponential increase in publication volume. John F. P. Bridges contributed to 40 publications and ranked first, followed by F. Reed Johnson (n = 37), Julie Ratcliffe (n = 36). The majority of the papers were conducted in the United States (n = 513) and the United Kingdom (n = 433). The top three cited journals were "Health Economics" (n = 981), "Value in Health" (n = 893), and "Pharmaceutical Economics" (n = 774), and the top three articles were "Constructing experimental designs for discrete-choice experiments: report of the ISPOR Conjoint Analysis Experimental Design Good Research Practices Task Force," "Conjoint analysis applications in health-a checklist: a report of the ISPOR Good Research Practices for Conjoint Analysis Task Force," and "Discrete choice experiments in health economics: a review of the literature." The research hotspots and trends included "health technology assessment," "survival," "preference based measure," and "health state valuation." Conclusion: The size of the literature about DCE studies in health care showed a noticeable increase in the past decade. The application of DCE in health care remains in an early growth phase, and "health technology assessment," "survival," "preference based measure," and "health state valuation" reflected the latest research hotpots and future trends.
    Keywords:  bibliometric analysis; conjoint analysis; discrete choice experiment; health care; survival
    DOI:  https://doi.org/10.3389/fpubh.2021.673698
  14. Clin Rheumatol. 2021 Jun 24.
    An analysis of scientometric data and publication policies of rheumatology journals.
    Gokhan Tazegul, Emre Emre, Tahir Saygın Öğüt, Veli Yazısız.
       OBJECTIVE: Scientometric indexes, based on citations, may be increased by open access (OA) publishing. We aimed to present the scientometric data of of rheumatology journals and analyze the scientometric data of rheumatology journals according to the OA publication policy.
    METHOD: Scientometric indexes and bibliometric data of 22 journals were obtained from Clarivate Analytics InCites, Scopus, and Scimago Journal & Country Rank websites. We included journal impact factor (JIF), CiteScore (CS), Hirsch index (HI), Source Normalized Impact per Paper (SNIP), Eigenfactor score (ES), and Scientific Journal Ranking (SJR). We separated the OA publishing policies into full OA and hybrid OA. The US dollar (USD) was used as the requested fee unit.
    RESULTS: All pairs of scientometric indexes had positive significant correlations. However, a journal in the first quartile of JIF was observed in the second quartile of CS, SNIP, and SJR, and the last quartile of ES and HI. Scientometric indexes of of full and hybrid OA journals were similar, apart from HI, which was higher in hybrid OA journals (p = 0.03, Mann-Whitney U test). However, full OA journal fees were less expensive by a median of 935 USD (p = 0.007, Mann-Whitney U test).
    CONCLUSION: We recommend that the JIF and HI pair or the ES paired with CS or SNIP be used together to evaluate rheumatology journals. We failed to show that the OA model positively affects the scientometric indexes of rheumatology journals; our results contradict the literature reporting that the OA publication model causes an increase in citations. Key Points •Clinicians should understand the scientometric indexes in rheumatology and if open access publishing affects citations (therefore, scientometric indexes). •The JIF and HI pair or the ES paired with CS or SNIP can be used to express different rankings since they are based on different databases and use different calculation methods. •We show that OA publication does not affect citations or scientometric indexes of rheumatology journals. •When choosing a rheumatology journal to publish OA, rheumatologists should consider individual OA citation patterns and APC charges together.
    Keywords:  Open access; Open access publishing; Rheumatology; Scientometrics; İmpact factor
    DOI:  https://doi.org/10.1007/s10067-021-05824-2
  15. Telemed J E Health. 2021 Jun 24.
    Evolution of Telepsychiatry: Scientometric Analysis of Telepsychiatry Publications Between 1986 and 2019.
    Ece Yazla, Engin Senel.
      Background: Although telepsychiatry has a long history, medical literature lacks a scientometric study evaluating telepsychiatry publications. The purpose of this study was to perform a holistic analysis of telepsychiatry articles published between 1986 and 2019. Methods: We used the "telepsychiatry" keyword for our search and included all documents indexed in Web of Science (Clarivate Analytics, USA) Core Collection between 1986 and 2019, revealing a total of 1,020 articles, of which only 224 were open access. Results: The peak year for publication was 2015, with 96 articles. The United States ranked first with 601 documents followed by Australia and Canada. The University of California and University of Washington were the most productive institutions and, again, 8 of the 10 leading institutions were from the United States. The peak year for citations was 2019, with a total of 2,080 records. Discussion: We believe that systematic approaches are needed to reveal the positive and negative features of telepsychiatry practice, especially from countries where this method is widely utilized, to elucidate the need for telepsychiatry in other countries/regions and to determine how its use can be increased in regions with limited access to health care workers. Conclusion: Although scientific interest in telepsychiatry appears to have increased almost every year since 1986, it has been observed that this interest is still concentrated in certain countries, such as the United States, Australia, and Canada, indicating that telepsychiatry may not have gained use in other countries.
    Keywords:  scientometric analysis; telemedicine; telepsychiatry
    DOI:  https://doi.org/10.1089/tmj.2021.0044
  16. J Food Sci. 2021 Jun;86(6): 2166-2168
    Tanner Awards for the Most-Cited Articles of 2018.
      
    DOI:  https://doi.org/10.1111/1750-3841.15207
  17. Res Int Bus Finance. 2020 Dec;54 101287
    Trade credit research before and after the global financial crisis of 2008 - A bibliometric overview.
    Debidutta Pattnaik, Mohammad Kabir Hassan, Satish Kumar, Justin Paul.
      This study presents an overview of the state-of-the-art in trade credit research by examining 1191 publications between 1955 and 2019. Applying bibliometrics and econometrics, the study compares the extant research across the three sub-domains of banking and finance, production and operations, and accounting. Findings suggest that the financial emergency in the global market had resulted in a watershed moment in trade credit research. About 69 % of the literature was found to have emerged after the global economic crisis of 2008. A network analysis grouped the trade credit articles into four major and four minor clusters. The banking and financing cluster exhibited the highest growth followed by the production and operation cluster while the perspectives of accounting are yet to gain traction. Conversely, reputation of the publishing hub, empirical studies, and the production and operational dimensions of the research positively and significantly influence citations. Alongside a thorough introspection, the study also provides new areas to direct the course of future research.
    Keywords:  Bibliographic coupling; Bibliometrics; COVID-19; Co-citation; Regression; Trade credit
    DOI:  https://doi.org/10.1016/j.ribaf.2020.101287
  18. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2021 ;77(6): 631-635
    [2. Impact Factor and Its Importance].
    Shigehiko Katsuragawa, Yoko Arai, Kunio Doi.
      
    DOI:  https://doi.org/10.6009/jjrt.2021_JSRT_77.6.631
  19. Spine (Phila Pa 1976). 2021 Jun 21.
    What is the Return on Investment of Spine Society Research Grants?
    Nelson Merchan, David N Bernstein, Noorullah Maqsoodi, Tochukwu Ikpeze, Addisu Mesfin.
       STUDY DESIGN: Retrospective, Observational Study.
    OBJECTIVE: The objective of this study is to evaluate the return on investment (ROI) of the Cervical Spine Research Society (CSRS), Scoliosis Research Society (SRS) and North America Spine Society (NASS) grants as quantified by the number of publications generated and federal grants obtained (National Institute of Health [NIH], Department of Defense [DOD]).
    SUMMARY OF BACKGROUND DATA: The CSR, SRS and NASS, have awarded numerous research grants over the past three decades.
    METHODS: Through publicly available data we identified grants awarded by the Spine Societies. We collected the type of grant awarded, the Principal Investigator information, dollar amount of the grant, number of publications in PubMed from each grant, number of citations, and the publication journal. The NIH and DOD website were queried to determine which grantees subsequently received either NIH or DoD funding.
    RESULTS: From 1989 to 2016: 81 (CSRS), 126 (SRS), and 93 (NASS) grants were awarded. From these grants 206 publications acknowledged receiving financial support from the spine societies. The SRS funded 100 papers, NASS 62 papers and CSRS 44 papers. A total of 32 NIH grants and 4 DOD grants were subsequently awarded. The conversion rate to NIH grants was 15% (n = 12 CSRS), 7.9% (n = 10 SRS), and 11% (n = 10 NASS). The conversion rate to DOD grants was 3.7% (n = 3 CSRS), 0.8% (n = 1 SRS), and 0% (n = 0 NASS). ROI of spine society grant dollars per future NIH and DoD grants were the lowest for CSRS (Dollars Per NIH Grant: $207,434; Dollars Per DoD Grant: $829,734). Male investigators received 85% of CSRS grants, 75% of SRS grants and 83% of NASS grants.
    CONCLUSION: CSRS grants appear to have the highest ROI of all spine society grants when evaluating subsequent NIH and DOD funding. However, the overall conversion rate to NIH and DOD grants remains low.Level of Evidence: 3.
    DOI:  https://doi.org/10.1097/BRS.0000000000004153
  20. CRISPR J. 2021 Jun;4(3): 313-320
    A Decade of CRISPR Gene Editing in China and Beyond: A Scientometric Landscape.
    Wuyuan Zhou, Yajun Yuan, Yaqun Zhang, Deng Chen.
      Since its Nobel Prize-winning breakthrough in 2012, CRISPR-Cas-based gene-editing system has emerged as one of the most promising biotechnologies in decades. In this article, we present an objective and comprehensive evaluation of CRISPR-based gene-editing technologies, including base editing and prime editing, based on the bibliometric analysis of 22,902 published records. We also assessed the status of CRISPR gene-editing technologies in academia from 2010 to 2020 globally, with respect to countries, institutions, and researchers, and used text clustering methods to assess technical trends and research hotspots. Our results indicate, not surprisingly, that this is a thriving and prominent area of research. By comparing the relevance and growth of CRISPR gene-editing technologies in China with other countries by several metrics, we show that the Chinese scientific community attaches considerable importance to the field of plant genome engineering, with more scholars from agricultural sectors than other sectors.
    DOI:  https://doi.org/10.1089/crispr.2020.0148
  21. Nature. 2021 Jun 25.
    Impact factor abandoned by Dutch university in hiring and promotion decisions.
    Chris Woolston.
      
    Keywords:  Careers; Institutions; Policy
    DOI:  https://doi.org/10.1038/d41586-021-01759-5
  22. World J Psychiatry. 2021 Jun 19. 11(6): 253-264
    Current global research landscape on COVID-19 and depressive disorders: Bibliometric and visualization analysis.
    Samah W Al-Jabi.
       BACKGROUND: Coronavirus disease 2019 (COVID-19) has affected daily life globally dramatically over the last year. The impact of the COVID-19 epidemic on mental health is expected to be immense and likely to be long-lasting, raising a range of global problems that need to be addressed accordingly.
    AIM: To analyze the Scopus-based depression research and COVID-19, explain the advancement of research nowadays, and comment on the possible hotspots of depression research and COVID-19 to obtain a more global perspective.
    METHODS: In this report, bibliometric analysis and visualization are used to explain COVID-19's global research status on depression and provide researchers with a guide to identify future research directions. Relevant studies on depression and COVID-19 were retrieved from the Scopus database. Visualization maps were produced using the VOSviewer software, including research collaboration.
    RESULTS: At the time of data collection (November 18, 2020), 77217 documents were released by Scopus to COVID-19 in all areas of research. By limiting the search to depression and COVID-19 (January 2020 up until November 18, 2020), there are 1274 published articles on depression and COVID-19 in the Scopus. The great majority of which are original articles (n = 1049, 82.34%), followed by 118 review articles (9.26%), 66 letters (5.18%). The United States had the highest number of publications at 282 (22.14%), followed by China (19.07%) at 243 and Italy at 121 (9.5%). The major two clusters are signified by mental health outcomes among the general population and mental health outcomes among health care workers.
    CONCLUSION: The evidence from this study found that many articles focused on mental health outcomes among the general population and health care workers. With adequate psychological support offered by the government or community agencies, mental health in various communities should be put within the local and global public health agenda. This changing situation involves the scientific community's collaborative efforts to contribute to population monitoring during quarantine and COVID-19 outbreaks and to examine the short- and long-term adverse effects on psychological well-being.
    Keywords:  Bibliometric; COVID-19; Depression; Psychological distress; Scopus
    DOI:  https://doi.org/10.5498/wjp.v11.i6.253
  23. PeerJ Comput Sci. 2021 ;7 e524
    In-text citation's frequencies-based recommendations of relevant research papers.
    Abdul Shahid, Muhammad Tanvir Afzal, Abdullah Alharbi, Hanan Aljuaid, Shaha Al-Otaibi.
      From the past half of a century, identification of the relevant documents is deemed an active area of research due to the rapid increase of data on the web. The traditional models to retrieve relevant documents are based on bibliographic information such as Bibliographic coupling, Co-citations, and Direct citations. However, in the recent past, the scientific community has started to employ textual features to improve existing models' accuracy. In our previous study, we found that analysis of citations at a deep level (i.e., content level) can play a paramount role in finding more relevant documents than surface level (i.e., just bibliography details). We found that cited and citing papers have a high degree of relevancy when in-text citations frequency of the cited paper is more than five times in the citing paper's text. This paper is an extension of our previous study in terms of its evaluation of a comprehensive dataset. Moreover, the study results are also compared with other state-of-the-art approaches i.e., content, metadata, and bibliography. For evaluation, a user study is conducted on selected papers from 1,200 documents (comprise about 16,000 references) of an online journal, Journal of Computer Science (J.UCS). The evaluation results indicate that in-text citation frequency has attained higher precision in finding relevant papers than other state-of-the-art techniques such as content, bibliographic coupling, and metadata-based techniques. The use of in-text citation may help in enhancing the quality of existing information systems and digital libraries. Further, more sophisticated measure may be redefined be considering the use of in-text citations.
    Keywords:  Citations; Digital Libraries; In-text Citation; Relevant Documents
    DOI:  https://doi.org/10.7717/peerj-cs.524
  24. Drug Des Devel Ther. 2021 ;15 2495-2505
    High-Impact Clinical Studies That Fomented New Developments in Anesthesia: History of Achievements, 1966-2015.
    Igor Kissin.
      The aim of this work is to identify the most influential initial clinical studies that fomented important developments in anesthesiology over the past 50 years. Studies fomenting new development can be selected using vastly different approaches and, therefore, might provide diverse outcomes. In the present work, two basic aspects of study assessments - the stage of development (eg, generation of idea, preclinical studies, clinical trials) and the method of selection (eg, committee vote, various types of citation analysis, method of finding the invention disclosure) - were chosen according to the following model. The stage of development: the initial clinical studies demonstrating the basic advantage of an innovation for providing anesthesia. The method: a combination of two factors - the study priority in terms of the time of its publication and the degree of its acknowledgement in the form of citation impact; the time of study publication was regarded as a primary factor, but only if the study's citation count was =/>20. The initial high-impact studies were selected for 16 drug-related topics (ketamine, isoflurane, etomidate, propofol, midazolam in anesthesia, vecuronium, alfentanil, atracurium, sevoflurane, sufentanil, rocuronium, desflurane, ropivacaine, remifentanil, dexmedetomidine in anesthesia, and sugammadex), and 9 technique-related topics (ultrasound-guided peripheral nerve block, capnography in anesthesia, target-controlled intravenous anesthesia, pulse oximetry in anesthesia, total intravenous anesthesia, transesophageal echocardiography in anesthesia, combined spinal-epidural anesthesia, and bispectral index). Twenty-five studies were designated the first high-impact studies (one for each topic); 16 are drug-related and 9 are technique-related. Half of the first high-impact studies had a citation count of =/>100, (range: 100 to 555). The citation count of the other half of high-impact studies did not reach the 100-citation threshold (range: 41 to 97). If a selected first high-impact study had a citation count <100, a next-on-timeline, additional study with citation count =/>100 was also selected; (range: 100 to 344). The present results show that an initial high-impact clinical study on a new development in anesthesiology can be determined and that related citations usually vary from one hundred to five hundred.
    Keywords:  anesthetic techniques; citation impact; clinical trials; drugs; priority rules; scientometrics
    DOI:  https://doi.org/10.2147/DDDT.S316636
  25. Environ Monit Assess. 2021 Jun 24. 193(7): 442
    Building new paths for responsible solid waste management.
    Maximilian Espuny, Antonio Faria Neto, José Salvador da Motta Reis, Sérgio Tenório Dos Santos Neto, Thais Vieira Nunhes, Otávio José de Oliveira.
      The amount of solid waste produced across the planet in the past decade was 1.3 billion tons (1.2 kg/year per person). Also, the significant number of publications on solid waste management (SWM) draws attention to the importance of discussing the topic to improve public health and to mitigate environmental impacts. The objectives of this article are to identify the state of the art and the scientific gaps on SWM and to propose a framework to promote it in the coming years. For this, a content analysis was carried out with the support of a bibliometric study, considering articles published in the Scopus database. The field of SWM study was classified into 12 different themes, and from this division, it was sought to identify the evolution of each of them between the 2005 and 2018 period. Content analysis and bibliometric study indicate that thermal and biological treatments are a promising trend to improve the performance of SWM. Its most important applied contribution is the generation of qualified information about SWM that can support the decision-making of public and private managers to reduce environmental impacts and improve life in urban spaces. The main academic contribution of the paper is the articulation of the most important themes on SWM, identifying the individual impact of each one of them in this field of study and the indication of the scientific trends that should guide the development of future research.
    Keywords:  Conservation of resources; Environmental impact; Solid waste management; Sustainability; Waste management
    DOI:  https://doi.org/10.1007/s10661-021-09173-0
  26. Int J Radiat Oncol Biol Phys. 2021 Jun 17. pii: S0360-3016(21)00738-0. [Epub ahead of print]
    The Holman Research Pathway in Radiation Oncology: 2010 - 2019.
    Kunal K Sindhu, Jared P Rowley, William H Smith, Anthony D Nehlsen, Andrew W Smith, Eric J Lehrer, Stanislav Lazarev, Kenneth E Rosenzweig, Michael Buckstein.
       PURPOSE: There has not been an assessment of the Holman Research Pathway (HRP) in radiation oncology (RO) in nearly 10 years. In this study, we sought to review the demographic characteristics, research productivity during and after residency, job placements, and National Institutes of Health (NIH) grant funding of RO residents who completed the HRP in the modern era.
    METHODS AND MATERIALS: We created a comprehensive database of RO residents who completed the HRP between 2010 and 2019. Utilizing a variety of data sources, we obtained demographic information, the first-author manuscripts published in residency, and the first- and last-author manuscripts published in the first 30 months after residency for each resident. In addition, we identified the first and current job and National Institutes of Health (NIH) grant funding for each resident.
    RESULTS: Ninety-seven RO residents, who graduated from 50 medical schools and 25 residency programs, were included. The majority were male (82.5%), had a PhD (92.8%), and identified as "White" (64.9%). Collectively, they published 212 first-author, PubMed-searchable manuscripts during residency (mean 2.2) and 142 first- or last-author, PubMed-searchable manuscripts in the first 30 months after the completion of residency (mean 1.5). The number of first-author publications authored by HRP graduates during residency was highly correlated (r = 0.62, p < 0.01) with the number of first- and last-author publications they authored in the first 30 months after completing residency. Ninety-six of the 97 residents (99.0%) have been employed in full-time clinical positions after completing residency. Seventy-six (78.4%) HRP residents obtained an academic position as their first job after residency, only four of whom have since left academia, and 20 (20.6%) obtained a non-academic position. Of the 75 HRP graduates currently employed in an academic position, 39 (52.0%) have their own laboratories. Twenty-three of the 96 (24.0%) HRP residents who secured employment in full-time clinical positions after residency switched jobs over the study period. Lastly, thirty-three of the 97 (34.0%) HRP residents have thus far received 47 extramural NIH research grants, 15 of which were R-01 grants.
    CONCLUSIONS: Over the past decade, the HRP has proven successful in training a new cohort of physician investigators in RO. While productive, HRP residents have had relatively homogenous gender, educational, and racial backgrounds. Ensuring sufficient representation of residents from a variety of backgrounds in the HRP in the future will be crucial.
    DOI:  https://doi.org/10.1016/j.ijrobp.2021.06.020
  27. CRISPR J. 2021 Jun;4(3): 321-338
    Tracking and Mapping the Use of CRISPR-Cas Systems for Research in China.
    Guillaume Levrier.
      Scientists have floated the idea of a "Sputnik 2.0" technological race between the People's Republic of China (PRC) and the United States of America in CRISPR-based genome editing research. This quantitative analysis of articles published between 2010 and 2020 shows that research centers based in the PRC have succeeded in making CRISPR-based genome editing a standard tool. A corpus of 18,863 academic documents containing the acronym CRISPR in their abstract shows that although PRC-based research institutions were slower to start publishing on CRISPR, they have now outpaced the publication rate of institutions located in the European Union (EU). While U.S.-based institutions have kept their leading position in basic research, PRC-based research has become momentous in agriculture-related fields. This corpus hence illustrates how deeply the international landscape of life sciences research has shifted since the Human Genome Project, mostly to the PRC's advantage.
    DOI:  https://doi.org/10.1089/crispr.2021.0015
  28. Explore (NY). 2021 Jun 05. pii: S1550-8307(21)00095-1. [Epub ahead of print]
    Academic studies on claimed past-life memories: A scoping review.
    Lucam J Moraes, Gabrielle S Barbosa, João Pedro G B Castro, Jim B Tucker, Alexander Moreira-Almeida.
      This study reviews observational studies regarding alleged past-life memories published as scientific articles, and points out their bibliometric and methodological characteristics. Scientific databases were screened (Scopus, Web of Science, PubMed/Medline, PsycINFO, Scielo, and OpenGrey). The 78 included studies were classified by their methodological and bibliometric characteristics. The peak of publications occurred from 1990 to 2010 (45%), and Asia was the most investigated territory (58 studies); most of investigations were related to children (84%) and case report was the predominant study design (60%). Interview was the predominant methodological approach (73%), followed by documental analysis (50%). Claimed past-life memories (100%), unusual behaviors (74%) and birthmarks/defects (37%) were the most investigated variables. Investigations of past-life memories should be encouraged around all cultures, and future studies should consider previous methodological features and try to overcome their limitations.
    Keywords:  Children; Life after death; Past-life memories; Reincarnation; Religion
    DOI:  https://doi.org/10.1016/j.explore.2021.05.006
  29. Eur J Gen Pract. 2021 Dec;27(1): 140-141
    Editors' choice: the most valued articles published in the European Journal of General Practice in 2020.
    Carl Llor, Jelle Stoffers.
      
    DOI:  https://doi.org/10.1080/13814788.2021.1940516
  30. Biopreserv Biobank. 2021 Jun 24.
    Vignettes to Illustrate the Value of Tumor Biobanks in Cancer Research in Canada.
    Tamsin Tarling, Lise Anne Marie Matzke, Amanda Rush, Brent Gali, Jennifer A Byrne, Peter H Watson.
      Background: Tumor biobanks are a common research infrastructure. As a collection of biospecimens and annotated data collected to support a multitude of research projects, biobanks facilitate access to materials that are the critical fuel for the generation of data in up to 40% of cancer research publications. However, quantifying how to measure biobanks' impact and their value on the field of cancer research discoveries and findings, has not been well elucidated. Methods: We have used a qualitative case study approach to illustrate the impact of tumor biobanks. We assessed the impact of three research studies published between 2010 and 2012 that required easily accessible "classic" biobanks. Each study utilized preassembled collections of tumor biospecimens with associated patient outcomes data at the outset of the research project. We compared the resulting journal impact factor, altmetric and field-weighted citation impact factor scores for each article to a set of six "benchmark" articles that represent cancer research and treatment discoveries from the same time period and two sentinel scientific discovery articles. Results: We developed a value model using a literature search and design-thinking methodologies to illustrate the contributions of these "classic" model biobanks to these research studies. Assessment of the three example articles supported by biobanks demonstrates that the output can have impact that is comparable to the impact of a set of benchmark articles describing milestones in the field of cancer research and cancer care. Conclusions: These case studies illustrate the value of the sustained investment of funds, planning, time, and effort on the part of the biobanks before the conduct of the research study to be able to ultimately support high-value research. The "value" model will enable further discussion around impact and may be useful in better delineating qualitative metrics of biobank value in the future.
    Keywords:  biobanking; biobanks; cancer; impact; research; value
    DOI:  https://doi.org/10.1089/bio.2021.0002
  31. Environ Sci Pollut Res Int. 2021 Jun 24.
    Gaps, biases, and future directions in research on the impacts of anthropogenic land-use change on aquatic ecosystems: a topic-based bibliometric analysis.
    Francisco J Fernández, Manuel Muñoz, Roberto D Ponce Oliva, Felipe Vásquez-Lavín, Stefan Gelcich.
      Anthropogenic land use change (ALUC) satisfies human needs but also impacts aquatic ecosystems. Aquatic ecosystems are intrinsically linked with terrestrial landscapes, an association that is already recognized as a key factor to address future research and effective governance. However, the complexity and range of the impact of ALUC in aquatic ecosystems have been fundamental challenges and have implicitly routed the analysis to particular segments, drivers, management, or effects of the theme. In this study, we present an attempt to frame the subject in a broader context through a topic-based bibliometric analysis. Our aim is to identify possible biases and gaps in the current scientific literature and detect the main topics that have characterized the theme. Our results show an unequal distribution of articles by country when we analyzed the authors' affiliation and also a slight increase in contributions from social and economic disciplines, although they are still underrepresented. Moreover, we distinguish topics whose prevalence seems to change, especially those topics where the use of scenario analysis and multi-stressors are considered. We discuss the main biases and gaps revealed by our results, concluding that future studies on the impact of ALUC on aquatic ecosystems should better integrate social and economic disciplines and expand geographic frontiers.
    Keywords:  Anthropogenic land use change; Aquatic ecosystems; Bibliometric analysis; Land use change impacts; Topic modeling; Water quality
    DOI:  https://doi.org/10.1007/s11356-021-15010-1
  32. J Vasc Surg. 2021 Jul;pii: S0741-5214(21)00319-0. [Epub ahead of print]74(1): 342
    The case for incorporating literature citations and social media mentions in one citation index.
    Faisal Aziz.
      
    DOI:  https://doi.org/10.1016/j.jvs.2021.02.020
  33. Urology. 2021 Jun 18. pii: S0090-4295(21)00526-4. [Epub ahead of print]
    Women are underrepresented in prestigious recognition awards in the American Urological Association.
    Jessica Wenzel, Anne Dudley, Rebecca Agnor, Solange Bassale, Yiyi Chen, Courtney Rowe, Casey A Seideman.
       OBJECTIVES: To determine the proportion of women who received awards from the American Urological Association (AUA) and evaluate whether this has changed over time as the proportion of practicing female urologists has increased.
    METHODS: A retrospective review of award recipients from the AUA website was performed. Gender of award recipient, type of award and year received were collected and the trend over time was compared with the AUA census.
    RESULTS: Of the 622 award recipients, 43 (6.9%) were women. There was a larger proportion of women who received early career awards (15/65; 23.1%) compared to women who received more prestigious mid (1/44; 2.3%) or senior (27/513; 5.3%) career awards. Additionally, 17/43 (39.5%) of female award recipients were not clinical urologists, compared to only 33/579 (5.7%) of male award recipients.
    CONCLUSIONS: Despite increased representation by women in the field of urology, women remain underrepresented in awards given by the AUA. Although the proportion of women receiving awards over time has increased, it remains less than expected given the increased proportion of practicing female urologists. Strategic initiatives should be employed to help advance women in academic urology.
    Keywords:  diversity equity and inclusion; gender equity; women in urology
    DOI:  https://doi.org/10.1016/j.urology.2021.03.058
  34. Oncologist. 2021 Jun 22.
    The Matilda Effect: Under-recognition of Women in Hematology and Oncology Awards.
    Shruti R Patel, Frederique St Pierre, Ana I Velazquez, Snegha Ananth, Urshila Durani, Andrea Anampa-Guzmán, Katerina Castillo, Natasha Dhawan, Amy S Oxentenko, Narjust Duma.
       BACKGROUND: The proportion of women in the field of hematology and oncology (H&O) has increased over recent decades, but the representation of women in leadership positions remains poor. In an effort to close the gender gap in academia, it is important to report on such inequities in hopes to close these gaps and improve career development.
    MATERIALS AND METHODS: We conducted a retrospective, observational study of published award recipients from 1994 to 2019 from the seven major H&O societies in the world. Gender was determined based on publicly available data. Chi-square and Cochran-Armitage tests were utilized for data analysis.
    RESULTS: Of the 1,642 awardees over the past 26 years, 915 met inclusion criteria. Award recipients were overwhelmingly men (77.9%) and non-Hispanic white (84.7%). Women awardees received 30.3% of the humanistic and education-related awards, while only receiving 16.0% of basic science awards (p < 0.01). Women represent 35.6% of all hematologists and oncologists, but only received 24.0% of awards given to these physicians (p = 0.004). Black, Hispanic, and Asian awardees represented 3.7%, 3.3%, and 6.8% of the total awardees, respectively.
    CONCLUSIONS: From 1994 to 2019, women were less likely to receive recognition awards from the seven major H&O societies studied compared to men. We also observed a considerably low proportion of minority awardees across all oncology subspecialties. Further studies examining how selection criteria favor either gender would be warranted in order to achieve equal representation in academic awards.
    IMPLICATIONS FOR PRACTICE: The proportion of women in the field of hematology/oncology has increased over recent decades, but representation in leadership positions remains poor. In this study, women and minority groups were found to be underrepresented amongst award recipients. Significant disparities were seen in disciplines that have been historically male-predominant, such as basic sciences. As awards on an international level enhance academic resumes and assist with career advancement, it is important that awards are being given in an equitable manner. First steps to promote diversity and inclusion in academic medicine is reporting of gender and racial disparities in various areas of academia.
    Keywords:  disparity; gender equity; recognition awards; workforce diversity
    DOI:  https://doi.org/10.1002/onco.13871
  35. F1000Res. 2021 ;10 198
    Characteristics, utilisation and influence of viewpoint articles from the Structured Operational Research and Training Initiative (SORT IT) - 2009-2020.
    Mohammed Khogali, Katie Tayler-Smith, Anthony D Harries, Rony Zachariah, Ajay Kumar, Hayk Davtyan, Srinath Satyanarayana, Olga Denisiuk, Johan van Griensven, Anthony Reid, Saw Saw, Selma Dar Berger, Veerle Hermans, Abraham Aseffa, John C Reeder.
      Background: The Structured Operational Research and Training Initiative (SORT IT) teaches the practical skills of conducting and publishing operational research (OR) to influence health policy and/or practice. In addition to original research articles, viewpoint articles are also produced and published as secondary outputs of SORT IT courses. We assessed the characteristics, use and influence of viewpoint articles derived from all SORT IT courses. Methods: This was a cross-sectional study involving all published viewpoint articles derived from the SORT IT courses held from August 2009 - March 2020. Characteristics of these papers were sourced from the papers themselves and from SORT-IT members involved in writing the papers. Data on use were sourced from the metrics provided on the online publishing platforms and from Google Scholar. Influence on policy and practice was self-assessed by the authors of the papers and was performed only for papers deemed to be 'calls for action'. Results: A total of 41 viewpoint papers were published. Of these, 15 (37%) were 'calls for action'. In total, 31 (76%) were published in open-access journals and the remaining 10 in delayed access journals. In 12 (29%) of the papers, first authors were from low and middle-income countries (LMICs). Female authors (54%) were included in 22, but only four (10%) and two (5%) of first and last authors respectively, were female. Only seven (17%) papers had available data regarding online views and downloads. The median citation score for the papers was four (IQR 1-9). Of the 15 'call for action' papers, six influenced OR capacity building, two influenced policy and practice, and three influenced both OR capacity building within SORT IT and policy and practice. Conclusion: Viewpoint articles generated during SORT IT courses appear to complement original OR studies and are valued contributors to the dissemination of OR practices in LMICs.
    Keywords:  SORT IT; policy and practice; utilization; viewpoints
    DOI:  https://doi.org/10.12688/f1000research.27349.1
  36. Clin Invest Med. 2021 Jun 14. 44(2): E1-4
    Team Science: Defining and Achieving Success.
    Meghan B Azad, Natalie Rodriguez.
      Meghan Azad was the 2020 recipient of the CSCI Joe Doupe Young Investigator Award. Azad and Rodriguez co-direct a $14M research portfolio funded by the Canadian Institutes of Health Research, the Canadian Foundation for Innovation and the Bill and Melinda Gates Foundation. Spanning 45 countries, their acclaimed pediatric research is well known in clinical circles, highly cited by the scientific community and widely shared on mainstream and social media. In 2020, Azad was recognized among the WXN Top 100 Most Powerful Women in Canada and Rodriguez was named among the CBC Manitoba Future 40 Finalists. Here they share their Top 10 Tips for defining and achieving success in Team Science.
    DOI:  https://doi.org/10.25011/cim.v44i2.36476
  37. ALTEX. 2021 Jun 17.
    The state of the scientific revolution in toxicology.
    Thomas Hartung, Aristides M Tsatsakis.
      Science changes in waves, the so-called paradigm shifts or scientific revolutions. This concept was prominently elaborated by Thomas S. Kuhn more than 50 years ago in what remains one of the most cited science philosophy books of all time. Kuhn described how "normal science" experiences anomalies, which bring it to crisis and revolution from which a new, immature scientific paradigm results, which over time becomes the new normal. Building on an analysis on how this applies to toxicology and its change in approach in 2008, we concluded at the time that toxicology had encountered a number of such anomalies and was moving into crisis. Here, the progress along Kuhn's trajectory over the last 12 years of a scientific revolution is discussed. We conclude that this decade has shown up even more anomalies, and the perception of crisis has spread and consolidated. Indications of revolutionary paradigm changes are emerging.
    Keywords:  alternative methods; new approach methods; paradigm shift; regulatory toxicology; science philosophy
    DOI:  https://doi.org/10.14573/altex.2106101
  38. Scientometrics. 2021 Jun 15. 1-33
    Mapping the intellectual structure of the coronavirus field (2000-2020): a co-word analysis.
    Aliakbar Pourhatami, Mohammad Kaviyani-Charati, Bahareh Kargar, Hamed Baziyad, Maryam Kargar, Carlos Olmeda-Gómez.
      Over the two last decades, coronaviruses have affected human life in different ways, especially in terms of health and economy. Due to the profound effects of novel coronaviruses, growing tides of research are emerging in various research fields. This paper employs a co-word analysis approach to map the intellectual structure of the coronavirus literature for a better understanding of how coronavirus research and the disease itself have developed during the target timeframe. A strategic diagram has been drawn to depict the coronavirus domain's structure and development. A detailed picture of coronavirus literature has been extracted from a huge number of papers to provide a quick overview of the coronavirus literature. The main themes of past coronavirus-related publications are (a) "Antibody-Virus Interactions," (b) "Emerging Infectious Diseases," (c) "Protein Structure-based Drug Design and Antiviral Drug Discovery," (d) "Coronavirus Detection Methods," (e) "Viral Pathogenesis and Immunity," and (f) "Animal Coronaviruses." The emerging infectious diseases are mostly related to fatal diseases (such as Middle East respiratory syndrome, severe acute respiratory syndrome, and COVID-19) and animal coronaviruses (including porcine, turkey, feline, canine, equine, and bovine coronaviruses and infectious bronchitis virus), which are capable of placing animal-dependent industries such as the swine and poultry industries under strong economic pressure. Although considerable research into coronavirus has been done, this unique field has not yet matured sufficiently. Therefore, "Antibody-virus Interactions," "Emerging Infectious Diseases," and "Coronavirus Detection Methods" hold interesting, promising research gaps to be both explored and filled in the future.
    Keywords:  COVID-19; Co-word analysis; Coronavirus; Emerging infectious diseases; Science mapping; Text mining
    DOI:  https://doi.org/10.1007/s11192-021-04038-2
  39. Int J Radiat Oncol Biol Phys. 2021 Jun 17. pii: S0360-3016(21)00740-9. [Epub ahead of print]
    United States Radiation Oncology Fellowship Growth from 2010-2020.
    Mudit Chowdhary, Sinéad O'Bryant, Gabrielle W Peters, Neha Vapiwala, Osama Mohamad, Trevor J Royce.
       PURPOSE: To provide a comprehensive analysis of radiation oncology (RO) fellowship growth from 2010-2020.
    MATERIALS AND METHODS: A collated database of RO fellowship programs and matriculants was created using 1) RO residency program (n=92) & graduates (n=2,082) web searches, 2) prospective American Society for Radiation Oncology (ASTRO) Career Center postings database, 3) Association of Residents in Radiation Oncology Fellowship Directory, 4) RO fellowship survey data, 5) ASTRO Membership Directory and 6) direct e-mail contact with fellowship program directors. Linear regression assessed statistical significance of RO fellowship program, position, and matriculant growth over time.
    RESULTS: From 2010 to 2020, the number of RO fellowship programs & annual positions significantly increased from 20 to 37 (1.60 increase/year, 95% CI 1.32-1.89, p<0.001) & 20 to 39 (1.81 increase/year, 95% CI 1.52-2.10, p<0.001), respectively. The most commonly offered fellowship disciplines were proton therapy (n=10), brachytherapy (n=7), stereotactic radiosurgery/stereotactic body radiotherapy (n=6), general RO (n=5) and customizable to trainees' interests (n=3). Only 10 (27%) fellowships had a formal curriculum. All fellowships were unaccredited. Four (10.8%) programs were offered at institutions without an ACGME-accredited RO residency training program, all established within the past 2 years. 54.8% (171/312) of available fellowship positions were filled between 2010-2020. Of these, 94 (55.0%) were graduates of US RO residency programs. The mean number of total fellows & US-residency trained fellows per year was 15 (range: 5-23) & 8 (range: 2-20), respectively. There was no significant increase in the number of annual matriculated fellows over time (p=0.077). Among US-residency trained fellows, 27 (28.7%), 37 (39.4%) and 29 (30.9%) were from small (≤6), medium (7-12) and large (>12) residency programs, respectively. Twenty-eight (29.8%), 13 (13.8%), 25 (26.6%) and 27 (28.7%) trained in the Northeast, Midwest, South and West, respectively.
    CONCLUSIONS: There has been significant growth in unaccredited RO fellowship programs and annual positions over the past decade, though the number of matriculants has remained stable. We report for the first time the recent establishment of fellowships at institutions without an ACGME-accredited RO residency program. The impact of fellowship programs on the training of RO residents should be studied.
    DOI:  https://doi.org/10.1016/j.ijrobp.2021.06.022
  40. Langenbecks Arch Surg. 2021 Jun 22.
    Surgery and the kings of medical science : Invited Commentary: "Publication activity of chief and senior general/visceral surgeons in German university hospitals - a ten-year analysis", Böckmann et al.
    Ihsan Ekin Demir, Güralp O Ceyhan, Helmut Friess.
       BACKGROUND: Surgeons are frequently compared in terms of their publication activity to members of other disciplines who publish in journals with naturally higher impact factors. The time intensity of daily clinical duties in surgery is yet not comparable to that of these competitor disciplines.
    PURPOSE: Here, we aimed to critically comment on ways for improving the academic productivity of university surgerons.
    CONCLUSIONS: To ensure high-quality science in surgery, it is imperative that surgeons actively ask for and generate the time for high-quality research. This necessitates coordinated and combined efforts of leading university surgeons at the political level and effective presentation of the magnificent studies performed by young and talented university surgeons.
    DOI:  https://doi.org/10.1007/s00423-021-02242-5
  41. Sports Med Open. 2021 Jun 22. 7(1): 43
    Female (Under) Representation in Exercise Thermoregulation Research.
    Kate P Hutchins, David N Borg, Aaron J E Bach, Joshua J Bon, Geoffrey M Minett, Ian B Stewart.
       BACKGROUND: Despite an increasing rate of women participating in professional sports, emergency services, and military settings where they are exposed to exertional heat stress, our understanding of female thermoregulation and the detrimental effects of heat on women's performance, especially regarding the menstrual cycle, is limited. This review aimed to quantify the representation of women in exercise thermoregulation research between 2010 and 2019 and the frequency that these articles reported details pertaining to female participants' menstrual cycle to determine the volume of novel research that is directly relevant to this growing population.
    METHODS: Original exercise thermoregulatory studies published in three major sports medicine databases (PubMed, MEDLINE, and SPORTDiscus) between 2010 and 2019 were surveyed. Articles were screened to determine the number of female and male participants in the study and whether studies involving women reported menstrual orientation or phase. Research involving healthy adult participants and an exercise protocol with a thermoregulatory outcome measure were included in the review.
    RESULTS: A total of 1407 articles were included in the review, involving 28,030 participants. The annual representation of women ranged from a mean of 11.6% [95% credible interval (CI); 9.2, 14.3] to 17.8% [95% CI; 15.2, 20.6] across the 10 years, indicating studies predominantly included men. Nonetheless, there was a small statistical increase in the overall proportion of women, with a mean overall proportion change of 0.7% [95% CI; 0.2, 1.2] per year. The increase appeared to be driven by a reduction in the number of studies including only men, rather than studies including more women alongside men, or increased women-only studies. Less than one third of articles involving women reported the menstrual orientation of participants and less than one quarter reported both menstrual orientation and phase. This study shows that women were proportionally underrepresented in exercise thermoregulation research during the past decade and the majority of studies did not report menstrual cycle details of female participants. Researchers should consider including women in future work where their inclusion could contribute meaningful data that enhance the evidence-based and ultimately improves our comprehension of women's thermal physiology.
    Keywords:  Exertional heat stress; Menstrual cycle; Performance; Sex differences; Temperature
    DOI:  https://doi.org/10.1186/s40798-021-00334-6
  42. Br Dent J. 2021 Jun 25.
    Speaking up for balance: analysis of the gender of invited speakers at UK dental conferences.
    Claudia Heggie, Sarah L McKernon, Laura Gartshore.
      Introduction Across healthcare, there is an urgent call to action to address systematic gender bias impeding equity for women. Gender imbalance exists for speakers at medical conferences. This research presents the first descriptive analysis of gender balance of speakers at dental conferences.Objectives Describe the gender balance of invited speakers at UK conferences of the dental specialties and general dentistry in a two-year period. Consider the findings in relation to gender balance of dental and specialist registrants.Method Gender, presentation length and professional role were extracted from conference programmes. Acceptable gender balance was pre-specified as 40-60%. Gender data were extracted from the GDC registration report.Results Of 352 invited speakers, 39.8% (n = 140) were identified as female and 60.2% (n = 212) as male. Gender was acceptably balanced in 21.4% (n = 3) of conferences. Gender balance of specialist speakers varied, as does gender distribution within the specialties themselves. Only 38.5% (n = 5) of specialties had a specialist speaker gender balance representative of their speciality.Conclusion There is a call for further research to drive equity in the characteristics of invited speakers and to determine whether there is correlation with representation in the composition of conference organising committees, leadership, professional roles and the workforce. Conference organisers are encouraged to strive proactively and prospectively towards representative programmes.
    DOI:  https://doi.org/10.1038/s41415-021-3072-2
  43. Nutr Diet. 2021 Jun 21.
    Statistical methods and software used in nutrition and dietetics research: A review of the published literature using text mining.
    Alison Coenen, Marijka J Batterham, Eleanor J Beck.
       AIM: Dietitians must be statistically literate to effectively interpret the scientific literature underpinning the discipline. Despite this, no study has been conducted that objectively identifies common statistical methods and packages specific to current nutrition and dietetics literature. This study aimed to identify statistical methods and software frequently used in nutrition and dietetics research.
    METHODS: A text mining approach using the bag-of-words method was applied to a random sample of articles obtained from all journals in the 'Nutrition and Dietetics' subject category within the SCImago Journal and Country Rank portal and published in 2018. A list of 229 statistical terms and 19 statistical software packages was developed to define the search terms to be mined. Statistical information from the methods section of included articles was extracted into Microsoft Excel (2016) for data cleaning. Statistical analyses were conducted in R (Version 3.6.0) and Microsoft Excel (2016).
    RESULTS: Seven hundred and fifty-seven journal articles were included. Numerical descriptive statistics were the most common statistical method group, appearing in 83.2% of articles (n = 630). This was followed by specific hypothesis tests (68.8%, n = 521), general hypothesis concepts (58.4%, n = 442), regression (44.4%, n = 336), and ANOVA (30.8%, n = 233). IBM SPSS statistics was the most common statistical software package, reported in 41.7% of included articles.
    CONCLUSION: These findings provide useful information for educators to evaluate current statistics curricula and develop short courses for continuing education. They may also act as a starting point for dietitians to educate themselves on typical statistical methods they may encounter.
    Keywords:  data mining; dietetics; education; evidence-based practice; nutritional sciences; statistics
    DOI:  https://doi.org/10.1111/1747-0080.12678
  44. Vis Comput Ind Biomed Art. 2021 Jun 24. 4(1): 19
    Visualizing risk factors of dementia from scholarly literature using knowledge maps and next-generation data models.
    Kiran Fahd, Sitalakshmi Venkatraman.
      Scholarly communication of knowledge is predominantly document-based in digital repositories, and researchers find it tedious to automatically capture and process the semantics among related articles. Despite the present digital era of big data, there is a lack of visual representations of the knowledge present in scholarly articles, and a time-saving approach for a literature search and visual navigation is warranted. The majority of knowledge display tools cannot cope with current big data trends and pose limitations in meeting the requirements of automatic knowledge representation, storage, and dynamic visualization. To address this limitation, the main aim of this paper is to model the visualization of unstructured data and explore the feasibility of achieving visual navigation for researchers to gain insight into the knowledge hidden in scientific articles of digital repositories. Contemporary topics of research and practice, including modifiable risk factors leading to a dramatic increase in Alzheimer's disease and other forms of dementia, warrant deeper insight into the evidence-based knowledge available in the literature. The goal is to provide researchers with a visual-based easy traversal through a digital repository of research articles. This paper takes the first step in proposing a novel integrated model using knowledge maps and next-generation graph datastores to achieve a semantic visualization with domain-specific knowledge, such as dementia risk factors. The model facilitates a deep conceptual understanding of the literature by automatically establishing visual relationships among the extracted knowledge from the big data resources of research articles. It also serves as an automated tool for a visual navigation through the knowledge repository for faster identification of dementia risk factors reported in scholarly articles. Further, it facilitates a semantic visualization and domain-specific knowledge discovery from a large digital repository and their associations. In this study, the implementation of the proposed model in the Neo4j graph data repository, along with the results achieved, is presented as a proof of concept. Using scholarly research articles on dementia risk factors as a case study, automatic knowledge extraction, storage, intelligent search, and visual navigation are illustrated. The implementation of contextual knowledge and its relationship for a visual exploration by researchers show promising results in the knowledge discovery of dementia risk factors. Overall, this study demonstrates the significance of a semantic visualization with the effective use of knowledge maps and paves the way for extending visual modeling capabilities in the future.
    Keywords:  Big data; Data visualization; Dementia; Graph database; Knowledge maps; Neo4j; Non-relational database; Semantic visualization
    DOI:  https://doi.org/10.1186/s42492-021-00085-x
  45. J Am Med Inform Assoc. 2021 Jun 21. pii: ocab084. [Epub ahead of print]
    The use of SNOMED CT, 2013-2020: a literature review.
    Eunsuk Chang, Javed Mostafa.
       OBJECTIVE: This article reviews recent literature on the use of SNOMED CT as an extension of Lee et al's 2014 review on the same topic. The Lee et al's article covered literature published from 2001-2012, and the scope of this review was 2013-2020.
    MATERIALS AND METHODS: In line with Lee et al's methods, we searched the PubMed and Embase databases and identified 1002 articles for review, including studies from January 2013 to September 2020. The retrieved articles were categorized and analyzed according to SNOMED CT focus categories (ie, indeterminate, theoretical, pre-development, implementation, and evaluation/commodity), usage categories (eg, illustrate terminology systems theory, prospective content coverage, used to classify or code in a study, retrieve or analyze patient data, etc.), medical domains, and countries.
    RESULTS: After applying inclusion and exclusion criteria, 622 articles were selected for final review. Compared to the papers published between 2001 and 2012, papers published between 2013 and 2020 revealed an increase in more mature usage of SNOMED CT, and the number of papers classified in the "implementation" and "evaluation/commodity" focus categories expanded. When analyzed by decade, papers in the "pre-development," "implementation," and "evaluation/commodity" categories were much more numerous in 2011-2020 than in 2001-2010, increasing from 169 to 293, 30 to 138, and 3 to 65, respectively.
    CONCLUSION: Published papers in more mature usage categories have substantially increased since 2012. From 2013 to present, SNOMED CT has been increasingly implemented in more practical settings. Future research should concentrate on addressing whether SNOMED CT influences improvement in patient care.
    Keywords:  SNOMED CT; Unified Medical Language System; electronic health record; medical ontology; systematized nomenclature of medicine
    DOI:  https://doi.org/10.1093/jamia/ocab084
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