bims-evares Biomed News
on Evaluation of research
Issue of 2021–05–16
38 papers selected by
Thomas Krichel, Open Library Society



  1. Cleft Palate Craniofac J. 2021 May 11. 10556656211014077
       OBJECTIVES: To identify research articles related to cleft lip and/or cleft palate (CL/P) that generated the highest online attention.
    METHODS: Altmetric Explorer was used to identify the 100 articles with the highest Altmetric Attention Score (AAS). Descriptive and correlation statistics were performed to study the characteristics of these articles in relation to their publication data, research type and domain, number of Mendeley readers, and dimensions citations. Citation counts were extracted from Scopus and Google Scholar.
    RESULTS: The median AAS for the top 100 outputs was 22 (range from 12 to 458). The outputs were mostly discussed on Twitter (median = 8; range = 0-131). Topics discussing treatment and care for patients with CL/P accounted for 38% of the articles with the highest AAS followed by etiology and risk factors (32%). The majority of articles originated from the USA (46%) followed by Europe (16%) and the United Kingdom (15%). No significant differences were observed in AAS among different study designs, topic domains, journals' ranking and impact factor, and the number of citations in Scopus and Google Scholar.
    CONCLUSIONS: Researchers should consider use of social platforms to disseminate their work among scholars and nonscholars. Altmetrics can be combined with traditional metrics for a more comprehensive assessment of research impact.
    Keywords:  Altmetric; alternative metrics; cleft lip and/or palate; online attention; research dissemination; social media
    DOI:  https://doi.org/10.1177/10556656211014077
  2. Clin Transl Sci. 2021 May 13.
      Research organizations are becoming more reliant on quantitative approaches to determine how to recruit and promote researchers, allocate funding, and evaluate the impact of prior allocations. Many of these quantitative metrics are based on research publications. Publication metrics are not only important for individual careers, but also affect the progress of science as a whole via their role in the funding award process. Understanding the origin and intended use of popular publication metrics can inform an evaluative strategy that balances the usefulness of publication metrics with the limitations of what they can convey about the productivity and quality of an author, a publication, or a journal. This article serves as a brief introduction to citation networks like Google Scholar, Web of Science Core Collection, Scopus, Microsoft Academic, and Dimensions. It also explains two of the most popular publication metrics: the h-index and the journal impact factor. The purpose of this article is to provide practical information on using citation networks to generate publication metrics, and to discuss ideas for contextualizing and juxtaposing metrics, in order to help researchers in translational science and other disciplines document their impact in as favorable a light as may be justified.
    Keywords:  Publication metrics; citations; h-index; journal impact factor; publications
    DOI:  https://doi.org/10.1111/cts.13067
  3. Spine (Phila Pa 1976). 2021 May 10.
       STUDY DESIGN: A bibliometric review of the literature.
    OBJECTIVE: The aim of this study was to identify the most highly cited articles relating to cervical myelopathy and to analyse the most influential papers.
    SUMMARY OF BACKGROUND DATA: Over the past several decades, a lot of research has been conducted regarding the subject of cervical myelopathy. While there are a large number of articles on this topic, to our knowledge, this is the first bibliometric analysis.
    METHODS: A selection of search terms and keywords were inputted into the 'Dimensions' database and the most highly cited articles in cervical myelopathy were selected from high impact factor journals. The top 100 articles were analysed for year of publication, authorship, publishing journals, institution and country of origin, subject matter, article type and level of evidence.
    RESULTS: The 100 most cited articles in the topic of cervical myelopathy were published from 1956-2015. These papers, their corresponding authors, and number of citations are shown in Table 1. The number of citations ranged from 121 times for the 100th paper to 541 times for the top paper in a total of 20 journals. The most common topic was operative technique while the journals which contributed the most articles were the Spine Journal and the Journal of Neurosurgery.
    CONCLUSION: Our study provided an extensive list of the most historically significant articles regarding cervical myelopathy, acknowledging the key contributions made to the advancement of this field.Level of Evidence: 5.
    DOI:  https://doi.org/10.1097/BRS.0000000000004100
  4. Osong Public Health Res Perspect. 2021 Apr;12(2): 126-135
       Objective: The aims of this study were to analyze the characteristics of the 100 top-cited articles on scrub typhus (ST), and to assess the present research landscape and future research directions using bibliometric analysis.
    Methods: Web of Science was used to conduct a bibliometric analysis of the 100 top-cited articles on ST. The articles were analyzed by publication year, number of citations, document type, journals, keywords, institutions, country of origin, and authorship.
    Results: The top 100 articles on ST were published between 1945 to 2017. The number of citations ranges from 39 to 227 and the interquartile range was 35.5. The United States published the highest number (n=21) of articles. Mahidol University was the most prolific institution in terms of articles (n=14). The American Journal of Tropical Medicine and Hygiene was the journal with the most articles (n=14), and Paris DH was the most productive author in terms of the Hirsh-index, which was 10 for that author. The study revealed a significant correlation between the total number of citations and the number of authors (r=0.668, p < 0.001), number of institutions (r=0.692, p < 0.001), number of years since publication (r=0.869, p < 0.001), and number of countries involved (r=0.963, p < 0.001).
    Conclusion: The findings of this study provide landmarks in the publication and citation frequency of the most influential articles on ST. In addition, this study provides useful information for readers and health policy-makers in evaluating the literature on ST.
    Keywords:  100 Top-cited articles; Bibliometric analysis; Scrub typhus
    DOI:  https://doi.org/10.24171/j.phrp.2021.12.2.10
  5. Environ Sci Pollut Res Int. 2021 May 12.
      Zerovalent iron (ZVI) has been a major focus of research and has attracted great attention during the last 2 decades by international researchers because of its excellent pollutant removal performance and several other merits in environmental remediation. Based on Web of Science Core Collection data, we present a comprehensive bibliometric analysis of ZVI research from 2000 to 2019. We analyze 4472 publications assuming three stages of growth trend of annual publication totals. We find that "The Chemical Engineering Journal" has been the most productive journal; Noubactep C is identified as the most productive author; China has been the most active country in this field and the Chinese Academy of Science the most productive institution. The timeline of keywords shows seven distinct co-citation clusters. In addition, the top 38 keywords with strong citation bursts are also detected, suggesting that the innovation of green composite synthesis of ZVI and nanoscale ZVI and its efficient removal capacity might be the prevailing research directions in the future.
    Keywords:  Bibliometric analysis; Environmental remediation; Research hotspot; Zerovalent iron
    DOI:  https://doi.org/10.1007/s11356-021-13847-0
  6. J Cerebrovasc Endovasc Neurosurg. 2021 May 12.
       Objective: Moyamoya disease (MMD) is a progressive steno-occlusive cerebrovascular phenomenon with unknown pathogenesis. Considering the abundance of articles addressing Moyamoya disease, a detailed analysis concerning the publication trends is of paramount importance. The aim of the study is to report the current knowledge of the top-100 most cited articles on Moyamoya disease in the literature.
    Methods: A non-time restricted keyword-based search was performed in June 2020 using the Scopus database. The search keywords included the following: "Moyamoya", "Moyamoya disease", and "Moyamoya syndrome". The search result was used to rank the articles based on their citation count. The top-100 most-cited articles were obtained and classified into seven categories.
    Results: A total of 3,543 articles on Moyamoya disease were published between 1955 and 2020. The Top-100 articles were published between 1977 and 2016 with a total of 16,119 citations, per year, and 7.23% rate of self-citation. The 1990s was the most productive decade (N=42). The most contributing country to the list was Japan (N=60). Stroke was the most active journal (N=23). Houkin, K., a Japanese neurosurgeon, was the most prolific author (N=15).
    Conclusions: Moyamoya disease has been extensively investigated in the literature throughout the years. The majority of articles published in the literature were addressing the surgical management and clinical outcome. Authors from neurosurgical backgrounds were the most active contributors to the field of Moyamoya disease.
    Keywords:  Moyamoya disease; Moyamoya syndrome; Stroke
    DOI:  https://doi.org/10.7461/jcen.2021.E2020.09.004
  7. Trans R Soc Trop Med Hyg. 2021 May 13. pii: trab072. [Epub ahead of print]
       BACKGROUND: Mycetoma is a neglected tropical disease that attracts little attention in regard to research and publications and hence this study was undertaken to determine the trends and global scientific research output in mycetoma-related fields.
    METHODS: Mycetoma data were retrieved from the Web of Science (WoS) and Scopus databases. The MeSH Browser was used to extract relevant keywords. Biblioshiny software (R-studio cloud), VOSviewer v. 1.6.6 and SPSS software were used for data management.
    RESULTS: Research trends on mycetoma increased globally from 1999 to 2020. The results were 404 documents (4444 citations) in WoS and 513 documents (5709 citations) in Scopus, and the average number of citations per article was 11 in WoS and 11.13 in Scopus. There was a significant association between the total number of citations and the total citations per year in both WoS (r=0.833, p<0.0001) and Scopus (r=0.926, p<0.0001). Sudan, India, the Netherlands and Mexico were the top-ranking productive countries for mycetoma publications in WoS, while India, the USA and Mexico were the top-ranking countries in Scopus. Articles on mycetoma were mainly published in PLoS Neglected Tropical Diseases, the International Journal of Dermatology and the Journal of Clinical Microbiology. A. H. Fahal from the Mycetoma Research Centre, University of Khartoum, Sudan, had the highest number of citations in mycetoma research during 1999-2020, followed by W. W. J. van de Sande from the Erasmus Medical Centre, University of Rotterdam, the Netherlands, during 2003-2020.
    CONCLUSION: The analysis provides insight into a global overview of Mycetoma research. In addition, the analysis holds a better understanding of the development trends that have emerged in Mycetoma over the past 21 years, which can also offer a scientific reference for future research.
    Keywords:  bibliometric analysis; global; mycetoma; research trend
    DOI:  https://doi.org/10.1093/trstmh/trab072
  8. Front Public Health. 2021 ;9 596128
      Background: The global incidence of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) is increasing, with increasing suicide reports. However, the bibliometric analysis of global research on PMS and PMDD is rare. We aimed to evaluate the global scientific output of research on PMS and PMDD and to explore their research hotspots and frontiers from 1945 to 2018 using a bibliometric analysis methodology. Methods: Articles with research on PMS and PMDD between 1945 and 2018 were retrieved from the Web of Science Core Collection (WoSCC). We used the bibliometric method, CiteSpace V and VOSviewer to analyze publication years, journals, countries, institutions, authors, research hotspots, and trends. We plotted the reference co-citation network, and we used keywords to analyze the research hotspots and trends. Results: We identified 2,833 publications on PMS and PMDD research from 1945 to 2018, and the annual publication number increased with time, with fluctuations. Psychoneuroendocrinology published the highest number of articles. The USA ranked the highest among the countries with the most publications, and the leading institute was UNIV PENN. Keyword and reference analysis indicated that the menstrual cycle, depression and ovarian hormones were the research hotspots, whereas prevalence, systematic review, anxiety and depression and young women were the research frontiers. Conclusions: We depicted overall research on PMS and PMDD by a bibliometric analysis methodology. Prevalence and impact in young women, systematic review evaluations of risk factors, and the association of anxiety and depression with menstrual cycle phases are the latest research frontiers that will pioneer the direction of research in the next few years.
    Keywords:  CiteSpace; PMS/PMDD; bibliometric analysis; menstrual cycle; trend
    DOI:  https://doi.org/10.3389/fpubh.2021.596128
  9. Front Pharmacol. 2021 ;12 624534
      Background: Peptide receptor radionuclide therapy (PRRT) is an emerging therapeutic option for the treatment of neuroendocrine tumors (NETs), and the number of publications in this field has been increasing in recent years. The aim of the present study was to present the research status and summarize the key topics through bibliometric analysis of published PRRT literature. Methods: A literature search for PRRT research from 2000 to 2019 was conducted using the Science Citation Index Expanded of Web of Science Core Collection (limited to SCIE) on August 4, 2020. The VOSviewer, R-bibliometrix, and CiteSpace software were used to conduct the bibliometric analysis. Results: From 2000 to 2019, a total of 681 publications (523 articles and 158 reviews) were retrieved. Annual publication outputs grew from three to 111 records. Germany had the largest number of publications, making the largest contribution to the field (n = 151, 22.17%). Active cooperation between countries/regions was observed. Kwekkeboom from the Erasmus Medical Center is perhaps a key researcher in the field of PRRT. The European Journal of Nuclear Medicine and Molecular Imaging and Journal of Nuclear Medicine ranked first for productive (n = 84, 12.33%) and co-cited (n = 3,438) journals, respectively. Important topics mainly included matters related to the efficacy of PRRT (e.g., 90Y-dotatoc and 177Lu-dotatate), the long-term adverse effects of PRRT (e.g., hematologic and renal toxicities), standardization of NETs and PRRT in practice, the development of medical imaging techniques, and the individual dose optimization of PRRT. Conclusion: Using bibliometric analysis, we gained deep insight into the global status and trends of studies investigating PRRT for the first time. The PRRT field is undergoing a period of rapid development, and our study provides a valuable reference for clinical researchers and practitioners.
    Keywords:  CiteSpace; R-bibliometrix; VOSviewer; bibliometrics; peptide receptor radionuclide therapy
    DOI:  https://doi.org/10.3389/fphar.2021.624534
  10. Liver Cancer. 2021 Apr;10(2): 137-150
       Introduction: Over the past 4 decades, the management of hepatocellular carcinoma (HCC) has changed dramatically. The publications that have had the most significant impact on HCC management have not been quantitatively analyzed. In this article, we analyzed the 100 most influential articles over the past 4 decades using bibliometric citation analysis to characterize the evolution in HCC treatment.
    Methods: The top-cited publications were identified and analyzed from the Clarivate Analytics Web of Science Core Collection database.
    Results: The 100 most cited articles were identified with an average of 738 citations (range: 349-6,799). There was an increase in the number of influential articles in the late 1990s, which was paralleled by an increase in reports focused on locoregional treatment of HCC. Most top 100 articles came from the USA (n = 35), followed by Italy (n = 28), mainland China (n = 26), and Japan (n = 24). The surgical management was the most studied topic (n = 33). The Annals of Surgery published the highest number of papers (n = 26) with 13,978 citations. While other 3 topics (surgical management, locoregional treatment, and outcome prediction) declined among publications beginning in the 2000s, there was an emergence of highly cited papers on targeted drugs and immune checkpoint inhibitors with a concomitant increase in the number of publications on systemic therapy.
    Conclusions: Based on bibliometric analysis of the literature over the last 40 years, a comprehensive analysis of the most historically significant HCC management articles highlighted the key contributions made to the evolution and advancement of this specialist field. The data should provide clinicians and researchers insight into future directions relative to the advancement of HCC management.
    Keywords:  Bibliometric analysis; Hepatocellular carcinoma; Management; Treatment
    DOI:  https://doi.org/10.1159/000513412
  11. Front Pharmacol. 2021 ;12 646626
      Background: Microbubbles are widely used as highly effective contrast agents to improve the diagnostic capability of ultrasound imaging. Mounting evidence suggests that ultrasound coupled with microbubbles has promising therapeutic applications in cancer, cardiovascular, and neurological disorders by acting as gene or drug carriers. The aim of this study was to identify the scientific output and activity related to ultrasound microbubble through bibliometric approaches. Methods: The literature related to ultrasound microbubble published between 1998 and 2019 was identified and selected from the Science Citation Index Expanded of Web of Science Core Collection on February 21, 2021. The Scopus database was also searched to validate the results and provided as supplementary material. Quantitative variables including number of publications and citations, H-index, and journal citation reports were analyzed by using Microsoft Excel 2019 and GraphPad Prism 8.0 software. VOS viewer and CiteSpace V were used to perform coauthorship, citation, co-citation, and co-occurrence analysis for countries/regions, institutions, authors, and keywords. Results: A total of 6088 publications from the WoSCC were included. The United States has made the largest contribution in this field, with the majority of publications (2090, 34.3%), citations (90,741, 46.6%), the highest H-index (138), and close collaborations with China and Canada. The most contributive institution was the University of Toronto. Professors De Jong N and Dayton P A have made great achievements in this field. However, the research cooperation between institutions and authors was relatively weak. All the studies could be divided into four clusters: "ultrasound diagnosis study," "microbubbles' characteristics study," "gene therapy study," and "drug delivery study." The average appearing years (AAY) of keywords in the cluster "drug delivery study" was more recent than other clusters. For promising hot spots, "doxorubicin" showed a relatively latest AAY of 2015.49, followed by "nanoparticles" and "breast cancer." Conclusion: There has been an increasing amount of scientific output on ultrasound microbubble according to the global trends, and the United States is staying ahead in this field. Collaboration between research teams still needs to be strengthened. The focus gradually shifts from "ultrasound diagnosis study" to "drug delivery study." It is recommended to pay attention to the latest hot spots, such as "doxorubicin," "nanoparticles," and "breast cancer."
    Keywords:  bibliometric analysis; hot spots; microbubble; research trends; ultrasound
    DOI:  https://doi.org/10.3389/fphar.2021.646626
  12. Sleep Breath. 2021 May 15.
       OBJECTIVE: This study aimed to explore the characteristics of the top 100 influential manuscripts on obstructive sleep apnea (OSA).
    METHODS: All manuscripts in English were searched from the Thomson Reuters Web of Science database by using OSA-related terms and ranked based on citation frequency. The top 100 influential manuscripts were selected and further analyzed by author, subject, journal, year of publication, country of origin, and institution.
    RESULTS: A total of 42,878 manuscripts were searched from the Web of Science. The top 100 influential manuscripts were published from 2005 to 2017, with a total citation frequency of 38,463 and a median citation frequency of 303 (range: from 210 to 2, 707). The American Journal of Respiratory and Critical Care Medicine published the largest number of manuscripts from the top 100 (n = 18; 5340 citations), followed by Sleep (n = 11; 3516 citations) and Chest (n = 7; 1784 citations). The most cited manuscript (Marin, J.M et al., Lancet 2005; 2707 citations) mainly analyzed long-term cardiovascular outcomes in men with OSA with/without continuous positive airway pressure. The most prevalent subject was associated diseases (n = 41), followed by treatments (n = 40). Most of the manuscripts were original articles (n = 63) based on observational clinical studies and published from American institutions (n = 60).
    CONCLUSIONS: Our study identified the top 100 influential manuscripts on OSA and provides insights into the characteristics of the most highly cited manuscripts to improve our understanding and management of OSA.
    Keywords:  Bibliometric analysis; Citations; Obstructive sleep apnea
    DOI:  https://doi.org/10.1007/s11325-021-02378-0
  13. R Soc Open Sci. 2021 Feb 10. 8(2): 201617
      Taxonomy is essential to biological sciences and the priority field in face of the biodiversity crisis. The industry of scientific publications has made extensive promotion and display of bibliometric indexes, resulting in side effects such as the Journal Impact Factor™ (JIF) mania. Inadequacies of the widely used indexes to assess taxonomic publications are among the impediments for the progress of this field. Based on an unusually high proportion of self-citations, the mega-journal Zootaxa, focused on zoological taxonomy, was suppressed from the Journal Citation Reports (JCR, Clarivate™). A prompt reaction from the scientific community against this decision took place exposing myths and misuses of bibliometrics. Our goal is to shed light on the impact of misuse of bibliometrics to the production in taxonomy. We explored JCR's metrics for 2010-2018 of 123 zoological journals publishing taxonomic studies. Zootaxa, with around 15 000 citations, received 311% more citations than the second most cited journal, and shows higher levels of self-citations than similar journals. We consider Zootaxa's scope and the fact that it is a mega-journal are insufficient to explain its high level of self-citation. Instead, this result is related to the 'Zootaxa phenomenon', a sociological bias that includes visibility and potentially harmful misconceptions that portray the journal as the only one that publishes taxonomic studies. Menaces to taxonomy come from many sources and the low bibliometric indexes, including JIF, are only one factor among a range of threats. Instead of being focused on statistically illiterate journal metrics endorsing the villainy of policies imposed by profit-motivated companies, taxonomists should be engaged with renewed strength in actions directly connected to the promotion and practice of this science without regard for citation analysis.
    Keywords:  Journal Impact Factor (JIF); bibliometrics; biodiversity crisis; scientometrics; systematics
    DOI:  https://doi.org/10.1098/rsos.201617
  14. Virol J. 2021 May 12. 18(1): 98
       BACKGROUND: In recent years, oncolytic viruses (OVs) have drawn attention as a novel therapy to various types of cancers, both in clinical and preclinical cancer studies all around the world. Consequently, researchers have been actively working on enhancing cancer therapy since the early twentieth century. This study presents a systematic review of the literature on OVs, discusses underlying research clusters and, presents future directions of OVs research.
    METHODS: A total of 1626 published articles related to OVs as cancer therapy were obtained from the Web of Science (WoS) database published between January 2000 and March 2020. Various aspects of OVs research, including the countries/territories, institutions, journals, authors, citations, research areas, and content analysis to find trending and emerging topics, were analysed using the bibliometrix package in the R-software.
    RESULTS: In terms of the number of publications, the USA based researchers were the most productive (n = 611) followed by Chinese (n = 197), and Canadian (n = 153) researchers. The Molecular Therapy journal ranked first both in terms of the number of publications (n = 133) and local citations (n = 1384). The most prominent institution was Mayo Clinic from the USA (n = 117) followed by the University of Ottawa from Canada (n = 72), and the University of Helsinki from Finland (n = 63). The most impactful author was Bell J.C with the highest number of articles (n = 67) and total local citations (n = 885). The most impactful article was published in the Cell journal. In addition, the latest OVs research mainly builds on four research clusters.
    CONCLUSION: The domain of OVs research has increased at a rapid rate from 2000 to 2020. Based on the synthesis of reviewed studies, adenovirus, herpes simplex virus, reovirus, and Newcastle disease virus have shown potent anti-cancer activity. Developed countries such as the USA, Canada, the UK, and Finland were the most productive, hence, contributed most to this field. Further collaboration will help improve the clinical research translation of this therapy and bring benefits to cancer patients worldwide.
    Keywords:  Bibliometric; Cancer; Dynamic co-citation; Oncolytic virus; Virotherapy
    DOI:  https://doi.org/10.1186/s12985-021-01571-7
  15. Zhongguo Zhong Yao Za Zhi. 2021 Apr;46(7): 1763-1768
      To analyze the study advance of Sophorae Tonkinensis Radix et Rhizoma, this study utilized CiteSpace 5.6.R5 software to conduct bibliometrics analysis on the Chinese literatures of Sophorae Tonkinensis Radix et Rhizoma from 1990 to 2020 included in the CNKI database retrieval platform. The analysis contents involved the number of published papers, co-authors, cooperative institutions, emergence, co-occurrence and clustering of keywords. A total of 808 Chinese literatures were included in the study, of which 17 were published by SUN Rong, the author with the most published papers, and formed a research team centered on SUN Rong; the analysis of the cooperation of publishing institutions showed that the Drug Safety Evaluation Research Center, Shanghai University of Traditional Chinese Medicine was the organization with the largest number of publications, with a total of 29 articles. It also formed a scientific research coorperation institution with Shandong Academy of Traditional Chinese Medicine as the core, and formed a relatively close cooperative network relationship. The analysis of literature keywords showed that the research direction was concentrated on the traditional Chinese medicine of Sophorae Tonkinensis Radix et Rhizoma, pharmacological mechanism, and side effects, active ingredients, etc. Among them, the research on the efficacy and toxicity of the active ingredients of Sophorae Tonkinensis Radix et Rhizoma has become a hot trend.
    Keywords:  Sophorae Tonkinensis Radix et Rhizoma; bibliometrics; medical value; visual analysis
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20201223.402
  16. Semin Ophthalmol. 2021 May 09. 1-6
      Purpose: To provide a brief review of literature on the journal impact factors (JIF) and the newer research metrics being proposed or implemented.Methods: The authors performed a PubMed search of articles published in the English language on the journal impact factors. Data captured include historical perspectives, evolution, calculation, criticisms of JIF and their rebuttals, and organized efforts to address JIF issues, alternate research metrics, and future directions. Specific emphasis was laid on evaluating the criticisms, current lacunae, and the changing practice patterns.Results: One of the measures to assess the research impact of an article is the number of citations it receives. Hence, citation-based metrics are commonly used for such purposes. While editors and well-known scholars refrain from attributing article success to the journal's prominence, the same is not true for most authors. JIF is still one of the top factors when deciding on an article submission. JIF is today an acceptable objective and quantifiable measure of knowledge dissemination. However, JIF should not be used as a surrogate measure to assess an individual researcher or an individual article. The reverence to JIF in this regard needs to be questioned. While alternate metrics or altmetrics have their advantages and limitations, they nevertheless augur well an era where scientometrics are complementary to one another without undue reliance on a sole parameter.Conclusion: While there is no need to demonize the JIF, its role in the scholarly assessment should be scaled down. The over-reliance and undue hype surrounding it should be discouraged at multiple scientific levels.
    Keywords:  Impact factor; Journal impact factor; Journal metrics; Research metrics; altmetrics
    DOI:  https://doi.org/10.1080/08820538.2021.1922713
  17. Rev Environ Health. 2021 May 11.
      Microbial fuel cells (MFCs) are eco-friendly and useful bioelectrical devices that harness the natural metabolisms of microbes to produce electrical power directly from organic materials. In this study, a bibliometric analysis is conducted to evaluate MFC research from 2001 to 2018 on the basis of the Science Citation Index Expanded database. Overall, MFC research has experienced a dramatic increase over last 18 years, with an exponential growth in the accumulated number of publications. Most publications are closely related to the industrialization and commoditization of MFCs, along with environmental issues, which are currently the biggest global challenges in MFC studies. A small proportion (4.34%) of the scientific journals published more than half (54.34%) of the total articles in the MFC field. Articles from the top 10 countries/regions accounted for the majority (83.16%) of the total articles, clearly indicating that advanced MFC technologies are currently dominated by these countries/regions. Moreover, an increasing number of MFC researchers are considering two-chamber and three-chamber MFC reactions. In particular, they are focusing on environmental technology instead of merely improving the efficiency of electricity generation. Materials research in the MFC field is still a popular area worldwide, and many researchers have focused on novel and eco-friendly cathode and anode developments. Meanwhile, only a few MFC studies are concerned with biological research.
    Keywords:  bibliometric; case study; dynamic analysis; environment and energy; microbial fuel cells
    DOI:  https://doi.org/10.1515/reveh-2020-0123
  18. Environ Sci Pollut Res Int. 2021 May 11.
      Using the extended science citation index database (SCI) and social science citation index (SSCI) databases, this paper analyzed the characteristics of publications, research foundations, research hotspots, and the evolutionary tracks of studies in the field of energy, environment, and climate change from 1990 to 2019 using a bibliometric method. This method is useful because it involves the quantitative analysis of large amounts of literature, using mathematical and statistical method. The results showed that the United States (US), the United Kingdom (UK), and China were the countries with the most published papers in the field. The US plays a key role in the cooperation between international institutions. An assessment conducted by the Intergovernmental Panel on Climate Change (IPCC) created the standard scientific reference for the research on climate change and its consequences. From 2006 to 2016, a large number of co-cited papers laid a solid foundation for research in the field. During this period, the research focused on the impact of climate change on the ecological environment, began to propose different countermeasures, and formed a set of mature research methods. From 2017 to 2019, there was an acceleration in the growth rate of the number of published articles. Strategies to address climate change, including renewable energy and energy transition, were the focus during this phase. Future studies are expected to focus on climate change mitigation strategies and energy policies. The findings provide a reference for researchers and can help policy makers balance economic development with environmental protection.
    Keywords:  Bibliometrics; Climate change; Energy; Environment
    DOI:  https://doi.org/10.1007/s11356-021-14059-2
  19. BMJ Glob Health. 2021 May;pii: e005672. [Epub ahead of print]6(5):
       INTRODUCTION: Diverse gender and geographical representation matters in research. We aimed to review medical and global health journals' sex/gender reporting, and the gender and geography of authorship.
    METHODS: 542 research and non-research articles from 14 selected journals were reviewed using a retrospective survey design. Paper screening and systematic data extraction was conducted with descriptive statistics and regression analyses calculated from the coded data. Outcome measures were journal characteristics, the extent to which published articles met sex/gender reporting guidelines, plus author gender and location of their affiliated institution.
    RESULTS: Five of the fourteen journals explicitly encourage sex/gender analysis in their author instructions, but this did not lead to increased sex/gender reporting beyond the gender of study participants (OR=3.69; p=0.000 (CI 1.79 to 7.60)). Just over half of research articles presented some level of sex/gender analysis, while 40% mentioned sex/gender in their discussion. Articles with women first and last authors were 2.4 times more likely to discuss sex/gender than articles with men in those positions (p=0.035 (CI 1.062 to 5.348)). First and last authors from high-income countries (HICs) were 19 times as prevalent as authors from low-income countries; and women from low-income and middle-income countries were at a disadvantage in terms of the impact factor of the journals they published in.
    CONCLUSION: Global health and medical research fails to consistently apply a sex/gender lens and remains largely the preserve of authors in HIC. Collaborative partnerships and funding support are needed to promote gender-sensitive research and dismantle historical power dynamics in authorship.
    Keywords:  descriptive study; public health
    DOI:  https://doi.org/10.1136/bmjgh-2021-005672
  20. J Pediatr Orthop. 2021 May 13.
       INTRODUCTION: Orthopaedic surgery remains a male-dominated specialty. To date there has not been a focused analysis of gender in authorship within the pediatric orthopaedic literature.
    METHODS: The electronic table of contents from 2011 to 2020 of 3 major pediatric orthopaedic journals [Journal of Children's Orthopedics (JCO), Journal of Pediatric Orthopedics (JPO), and Journal of Pediatric Orthopedics Part B (JPO-B)] were reviewed. Publications were reviewed for the number of articles with at least 1 female author and the number of articles with women listed as first authors. These were compared over the 10-year study period, and by individual year of publication. Statistical analysis included a general linear model with factorial one-way anslysis of variance and Bonferroni post hoc testing.
    RESULTS: A total of 4097 articles were reviewed. In 2020, there was a significantly higher percentage of articles with a female author when compared with 2011 (64% to 42%, P=0.010). A female was listed as first author in significantly more publications in 2020 as compared with 2011 (23% to 10%, P=0.031). During the 10-year study period, the highest mean proportion of articles with at least 1 female author was seen in JPO (60%), with similar findings in JCO (55%). Significantly fewer articles in JPO-B contained a female author (37%, P=0.001). The highest percentage of publications with a female first author across 10 years was in JCO (22%), followed by JPO (20%). Significantly fewer articles with a female first author were found in JPO-B (9%, P=0.001).
    CONCLUSION: There is an increasing proportion of publications in the pediatric orthopaedic literature with female authors and female first authors from 2011 to 2020. In addition, there was a statistical difference in female authorship when comparing specific publications, which should be investigated further.
    LEVEL OF EVIDENCE: Level IV.
    DOI:  https://doi.org/10.1097/BPO.0000000000001844
  21. Front Res Metr Anal. 2021 ;6 651991
      This paper presents a methodological proposal based on the identification of highly cited papers (HCPs) at domestic-level in the Spanish Public University System (SUPE), in order to find the most outstanding publications in the local context. The principal aim is to detect different activity and impact profiles among Spanish universities and differentiate those institutions that play a more significant role. To determine which and how many are the highly cited papers at the domestic level (HCP-DL) collected in the Web of Science, three citation thresholds (1, 5, and 10%) were established. Thematic classification in Incites/Essential Science Indicators areas is used. The results show a preponderance of HCPs in the field of Space Science, while the polytechnic universities have high visibility in the Computer Science area. It has been observed that the presence of HCPs in a given area is involved with universities specialized in teaching and research activities. In absolute terms, the big non-specialized universities are major producers of HCPs and hold the leading positions in our results. However, when efficiency is analyzed in relative terms, some small, specialized universities reveal themselves to be more efficient at producing HCPs (% of HCPs or citations per HCP). We think that this methodology, due to its simplicity, its ease of calculation, and the knowledge it provides, can be very useful to analyze the national systems of any country, in order to know the impact and visibility of the research carried out in its scientific institutions or research areas.
    Keywords:  Spanish universities; higher education institutions; highly cited papers; impact indicators; visibility indicators
    DOI:  https://doi.org/10.3389/frma.2021.651991
  22. Clin Imaging. 2021 Apr 20. pii: S0899-7071(21)00159-5. [Epub ahead of print]76 222-227
       OBJECTIVE: Traditional and open-access publication models have been increasingly scrutinized, particularly in light of the recent impasse regarding cost and access between Elsevier and the University of California. Peer-reviewed publications are the main source through which science is disseminated, yet the industry remains an enigma to most. Our aim was to determine radiology publisher market-share, access type, geographic distribution and relative research impact in order to better understand the traditionally opaque realm of academic publishing.
    METHODS: During April 2020, Scopus was queried to extract all entries in the "Radiology, Nuclear Medicine and Imaging" subcategory of "Medicine." Journal name, publisher, SCImago Journal Ranking (SJR) score, country and publication model were cataloged. Publishers were grouped by their ownership type and journals were grouped by their publication model. Overall trends were assessed across publisher type, publication model, and geographic location.
    RESULTS: Commercial publishers are used by 82% (239 of 293) of radiology journals. Elsevier and Springer Nature together published 40% (118/293) of journal titles within the category. Approximately one fourth (77/293) of radiology journals were open-access. On average, SJRs were highest for journals published commercially. Mean SJR across the top 10 publishers and publication model were similar (p = 0.06 and p = 0.48, respectively).
    DISCUSSION: Radiology journal publication is heavily consolidated amongst a few global commercial organizations. Most radiology journals were subscription-based, but their impact did not differ significantly from open-access counterparts. Further disputes between universities and publishers could influence future manuscript submission, review, and citation, which has the potential to destabilize traditional publication models.
    Keywords:  Journal publishers; Open access; Publication model
    DOI:  https://doi.org/10.1016/j.clinimag.2021.04.005
  23. Acta Biomed. 2021 May 12. 92(2): e2021058
      Backround: Moroccan Physicians in Physical Medicine and Rehabilitation (MP PMR) seek recognition at the international and national levels through publications. To our knowledge, no bibliometrics have been made to quantify these publications in indexed international journals. The aim is to quantify the publications MP PMR in indexed international journals. Methods and materiel: Is an observational study, we searched all the articles of the MP PMR published in the PubMed database until December 2019. The number of MP PMR articles was reported by academic academic centers, article type and indexed journal type. Results: We have found 26 articles since the creation of PMR in Morocco. The number of articles is correlated with the number of MP PMR remaining to 75 doctors and especially the ten professors. However, their contribution compared to their colleagues from other countries is promising. Scientific publications were limited to clinical cases in half of the cases. English was the dominant language of the works. Collaboration with foreign PMR was only with the French in 38.46% of cases. Only one French magazine took 34.61% of the works. Conclusion:  A lot of effort needs to be made by everyone, MP PMR and politicians to improve the quality and quantity of publications, research methodology and medical writing is one way, learning English in is another. Collaboration with other foreign collaborators is a necessity for a better visibility of publications.
    DOI:  https://doi.org/10.23750/abm.v92i2.9382
  24. J Med Internet Res. 2021 May 12.
       BACKGROUND: People engage in health information seeking behavior (HISB) to support health outcomes. Being able to predict a person's behavior can inform the development of interventions to guide effective health information seeking. Obtaining a comprehensive list of the predictors of HISB through a systematic search of the literature and exploring the inter-relationship of these predictors are important first steps in this process.
    OBJECTIVE: This study aimed to; identify significant predictors of HISB in the primary literature; develop a common taxonomy for predictors of HISB; and identify the evolution of the HISB research field.
    METHODS: A systematic search of PsycINFO, Scopus and PubMed was conducted for all years up to and including 10/12/2019. Quantitative studies identifying significant predictors of HISB were included. Information seeking was defined broadly and not restricted to any one source of health information. Data extraction of the significant predictors was performed by two authors. A network analysis was conducted to observe relationships between predictors over time.
    RESULTS: A total of 9549 articles were retrieved, and after screening, 344 studies were retained for analysis. A total of 1595 significant predictors were identified. These predictors were categorized into 67 predictor categories. The most central predictors were age, education, gender, health condition and financial income. Over time, the inter-relationship of predictors in the network became denser, with the growth of new predictor grouping reaching saturation (1 new predictor identified) in the past 7 years, despite increasing publication rates.
    CONCLUSIONS: A common taxonomy was developed, classifying 67 significant predictors of HISB. A time-aggregated network method was developed to track the evolution of research in HISB field, showing a maturation of new predictor terms and an increase in primary studies reporting multiple significant predictors of HISB. HISB research literature has experienced evolution with decreased characterization of novel predictors of HISB over time. A parallel increase in the complexity of predicting HISB has been identified with an increase in literature describing multiple significant predictors of HISB.
    CLINICALTRIAL:
    DOI:  https://doi.org/10.2196/21680
  25. Otol Neurotol. 2021 Jun 01. 42(5): 659-665
       OBJECTIVE: To assess otology and neurotology authorship by gender, subject, and country of origin from 2000 to 2019.
    STUDY DESIGN: Retrospective review of otology and neurotology publications in 2000, 2005, 2010, 2015, and 2019 from 10 prominent journals within otolaryngology.
    MAIN OUTCOME MEASURES: Demographics for first through third and final authors, including gender, degree, coauthorship, as well as number of authors, subject matter, and region of origin for each publication.
    RESULTS: A total of 4,411 neurotology articles published in 2000, 2005, 2010, 2015, and 2019 were analyzed. During the study period, the proportion of female authors increased from 22.3% in 2000 to 33.9% in 2019 (p < 0.0001). However, authorship position analysis demonstrated no increase in final female authorship (22.5% in 2019, from 19.4% in 2000, p = 0.112). Geographic region analysis demonstrated a similar overall global trend toward an increase in female authors. When considering author gender by position, North America, the Middle East, and Africa failed to demonstrate significant increasing trends for female final authors. Female final authors were also significantly less likely to have medical degrees than final male authors, (37.4% versus 78.6%, respectfully, p =  < 0.0001). Finally, women published more often within the subjects of pediatrics and audiology (46.5% and 37.3% of final authors, p < 0.0001).
    CONCLUSIONS: Female authorship in otology and neurotology has increased globally. With the predominant number of articles originating from North America, and articles originating from North America failing to demonstrate an increase in female final authorship, overall, final female authorship did not change during the study period.
    PROFESSIONAL PRACTICE GAP AND EDUCATIONAL NEED: There is no comprehensive study exploring gender distribution within only the specialty of otology and neurotology. While it is known that more women are becoming otolaryngologists, it is unknown if this increase is reflected in otology and neurotology publications, domestically and internationally.
    LEARNING OBJECTIVE: To understand if gender biases and/or differences exist within otology and neurotology publications.
    DESIRED RESULT: Identify trends in otology and neurotology publications to address particular barriers to female publication within the field.
    DOI:  https://doi.org/10.1097/MAO.0000000000003067
  26. F1000Res. 2020 ;9 654
      Background: Sporotrichosis has recently emerged as an important mycosis worldwide, with diverse transmission and epidemiologic profiles. For instance, in Brazil most cases are related to zoonotic transmission from naturally infected cats, and the majority of cases in China are due to external injury with environmental materials. Publications on sporotrichosis and on its etiologic agent may guide the direction of the research in this field. It can also define priorities for future studies. Methods: In this study, we evaluated the trends of global research in Sporothrix and sporotrichosis, based on publications records retrieved from Scopus and Web of Science databases for the period of 1945 to 2018. The overall productivity in the field, its geographical and temporal distribution, research themes, co-authorship networks, funding sources, and the implications of research findings for health practice were assessed using bibliometric approaches. Results: A total of 4,007 unique publications involving 99 countries were retrieved, most of them published after 2000. Authors based on institutions from the United States of America and Brazil accounted for 57.4% of the publications. Brazil was the leading country in terms of research collaboration and networking, with co-authorship with 45 countries. The thematic mapping revealed a temporal shift from clinical to applied research. Despite the large number of countries publishing in this field, most of funded studies came from Brazil, Mexico, China, South Africa, or the United States of America. The analysis of content identified few specific public health recommendations for prevention, case-management, or research. Moreover, most papers do not have a clearly defined intended audience. Conclusion: As the research in this field is emerging in several countries, with the generation of a large amount of data, it is necessary that scientists strengthen efforts to translate the research results into practice to curb this neglected infection.
    Keywords:  Bibliometrics; Network; Scientometry; Sporothrix; Sporotrichosis
    DOI:  https://doi.org/10.12688/f1000research.24250.1
  27. Front Endocrinol (Lausanne). 2021 ;12 665912
      Thousands of papers on primary aldosteronism (PA) have been published in the last two decades. This study aimed to evaluate the research hotspots and future trends in PA research using bibliometric analysis. A total of 2,365 PA research papers between 2000 and 2020 were included. The dominant position of the United States in global PA research throughout this 20-year period was evident, and it was also the country most frequently involved in international cooperation. The University of Padua was the most productive institution and a leader in research collaboration. The Journal of Clinical Endocrinology & Metabolism was the most productive journal in terms of the number of publications on PA. Further, Mulatero P, Reincke M, Beuschlein F and Wu VC all made significant contributions to PA research. Five hotspots have been identified: (1) metabolic syndrome associated with PA; (2) molecular mechanisms of PA; (3) adrenal adenoma and adrenal cortex; (4) hypertension associated with PA; and (5) clinical monitoring parameters and diagnosis in patients with PA. Our results suggest that the molecular mechanisms of PA will remain research hotspots in the future. International collaboration is also expected to widen and deepen in the field of PA research.
    Keywords:  VOSviewer; bibliographic item co-occurrence matrix builder; bibliometric analysis; primary aldosteronism; research hotspots
    DOI:  https://doi.org/10.3389/fendo.2021.665912
  28. BMJ Glob Health. 2021 05;pii: e005690. [Epub ahead of print]6(5):
       BACKGROUND: The COVID-19 pandemic has led to an unprecedented global research effort to build a body of knowledge that can inform mitigation strategies. We carried out a bibliometric analysis to describe the COVID-19 research output in Africa in terms of setting, study design, research themes and author affiliation.
    METHODS: We searched for articles published between 1 December 2019 and 3 January 2021 from various databases including PubMed, African Journals Online, medRxiv, Collabovid, the WHO global research database and Google. All article types and study design were included.
    RESULTS: A total of 1296 articles were retrieved. 46.6% were primary research articles, 48.6% were editorial-type articles while 4.6% were secondary research articles. 20.3% articles used the entire continent of Africa as their study setting while South Africa (15.4%) was the most common country-focused setting. The most common research topics include 'country preparedness and response' (24.9%) and 'the direct and indirect health impacts of the pandemic' (21.6%). However, only 1.0% of articles focus on therapeutics and vaccines. 90.3% of the articles had at least one African researcher as author, 78.5% had an African researcher as first author, while 63.5% had an African researcher as last author. The University of Cape Town leads with the greatest number of first and last authors. 13% of the articles were published in medRxiv and of the studies that declared funding, the Wellcome Trust was the top funding body.
    CONCLUSIONS: This study highlights Africa's COVID-19 research and the continent's existing capacity to carry out research that addresses local problems. However, more studies focused on vaccines and therapeutics are needed to inform local development. In addition, the uneven distribution of research productivity among African countries emphasises the need for increased investment where needed.
    Keywords:  COVID-19; other study design; public health
    DOI:  https://doi.org/10.1136/bmjgh-2021-005690
  29. PLoS One. 2021 ;16(5): e0251493
      Classification schemes for scientific activity and publications underpin a large swath of research evaluation practices at the organizational, governmental, and national levels. Several research classifications are currently in use, and they require continuous work as new classification techniques becomes available and as new research topics emerge. Convolutional neural networks, a subset of "deep learning" approaches, have recently offered novel and highly performant methods for classifying voluminous corpora of text. This article benchmarks a deep learning classification technique on more than 40 million scientific articles and on tens of thousands of scholarly journals. The comparison is performed against bibliographic coupling-, direct citation-, and manual-based classifications-the established and most widely used approaches in the field of bibliometrics, and by extension, in many science and innovation policy activities such as grant competition management. The results reveal that the performance of this first iteration of a deep learning approach is equivalent to the graph-based bibliometric approaches. All methods presented are also on par with manual classification. Somewhat surprisingly, no machine learning approaches were found to clearly outperform the simple label propagation approach that is direct citation. In conclusion, deep learning is promising because it performed just as well as the other approaches but has more flexibility to be further improved. For example, a deep neural network incorporating information from the citation network is likely to hold the key to an even better classification algorithm.
    DOI:  https://doi.org/10.1371/journal.pone.0251493
  30. Front Res Metr Anal. 2021 ;6 622006
      Scientometric indicators are useful to evaluate the relevance of scientific research, to prepare rankings, and to evaluate and inform research policies. That is why the choice of appropriate indicators is a matter of primary concern. This article aims to introduce a framework to decide the appropriate type of indicator for assessing the citation-based performance of complex innovation systems. The framework is two-fold: First, it brings the methodology to decide when the use of standard average based indicators is granted, and when scale-invariant indicators are mandatory. Second, it provides the procedures to build scale-invariant indicators to assess the relative impact of complex innovation systems. The framework is validated empirically through the evaluation of the relative impact of the Chilean science system in 2017. The result suggests that the Chilean science system has characteristics of a complex innovation system such as the distribution of citations fits to a power law with an exponential cutoff -2.77±0.09 and a power-law correlation between the size of the system and its impact 1.29±0.11 . Furthermore, the framework shows to be efficient to compare fields of vastly different sizes.
    Keywords:  citation impact analysis; complex innovation system; national science systems; power-law; relative impact; scale-independent; self-similarity
    DOI:  https://doi.org/10.3389/frma.2021.622006
  31. Front Res Metr Anal. 2020 ;5 595299
      Dimensions was built as a platform to allow stakeholders in the research community, including academic bibliometricians, to more easily create and understand the context of different types of research object through the linkages between these objects. Links between objects are created via persistent identifiers and machine learning techniques, while additional context is introduced via data enhancements such as per-object categorisations and person and institution disambiguation. While these features make analytical use cases accessible for end users, the COVID-19 crisis has highlighted a different set of needs to analyze trends in scholarship as they occur: Real-time bibliometrics. The combination of full-text search, daily data updates, a broad set of scholarly objects including pre-prints and a wider set of data fields for analysis, broadens opportunities for a different style of analysis. A subset of these emerging capabilities is discussed and three basic analyses are presented as illustrations of the potential for real-time bibliometrics.
    Keywords:  COVID-19 crisis; collaboration; dimensions; full text search; gender; peer review; real-time bibliometrics; timescale
    DOI:  https://doi.org/10.3389/frma.2020.595299
  32. Acta Biomed. 2021 May 12. 92(2): e2021207
       BACKGROUND AND AIM: The aim of this research was to review the articles published by the Otolaryngology (ORL) departments of the Italian University Hospitals in 2019 and in 2020 in order to analyze the impact of the COVID-19 pandemic on the academic production.
    METHODS: PubMed and Scopus were searched for the articles published by the ORL departments of the Italian Universities in 2019 and in 2020. The main eligibility criteria were English-language articles, while there were no exclusion criteria related to topic. The articles were classified into seven domains corresponding to the main ORL subspecialties.
    RESULTS: There was an overall increase in the number of articles by the 42.2% in 2020. Publications pertaining Rhinology and Laryngology increased more significantly in 2020, respectively by the 50.5% and 72.2%. Additionally, there was an increase in the number of articles concerning topics of general interest, by the 95.2% in 2020. Also, the citation trends of the articles published by the Italian University Hospitals increased remarkably in 2020.
    CONCLUSIONS: These results evidenced an overall increase in the number of ORL articles. Although 2020 is going to be remembered as a year to forget, it should be acknowledged for being the "golden year of research".
    DOI:  https://doi.org/10.23750/abm.v92i2.11557
  33. J Autism Dev Disord. 2021 May 11.
      The present study explored the shift from understanding to intervention to population impact in the empirical research published in this journal at five points of time over 40 years since the release of DSM-III. Two-thirds of the more than 600 original studies identified involved basic research, a pattern that is consistent with previous analyses of research funding allocations and that did not change over time. One of every eight studies involved intervention research, which occurred in community-based programs only about one-quarter of the time. These gaps in intervention research and community impact did not improve over time. The findings underscore the need to broaden the training and experience of researchers, and to re-consider priorities for research funding and publication.
    Keywords:  Applied research; Autism spectrum disorder; Basic research; Community programs; Intervention research; Publication trends; Review
    DOI:  https://doi.org/10.1007/s10803-021-05052-2
  34. Sci Prog. 2021 Apr-Jun;104(2):104(2): 368504211016936
      The current COVID-19 pandemic situation has stimulated an unplanned clinical research paradigm which is evident from the surge of clinical trial registrations and the increasing number of COVID-related publications. We aimed to explore the standards for research conduction, publications and retraction of articles related to COVID-19 pharmacotherapy research during the pandemic. We analysed data from the contemporary literatures on studies reporting pharmacological agents for COVID-19 using MEDLINE, PubMed, WHO database and Google Scholar between January 01, 2020 and March 20, 2021. The initial search revealed a total of 61,801 articles. Based on the inclusion criteria, a total of 124 studies related to various pharmacological agents were included in the final analysis. Most of the studies were reported from the United States (n = 30, 24%). Of the 124 studies, 50 (40%) were randomized controlled trials (RCTs). Immunomodulatory drugs-related (n = 17, 34%) and COVID-19 vaccine-related studies (n = 14, 28%) were the main topics in the relevant RCTs. The median days for dissemination of findings in journals were 114 days (IQR 61-189). A comparative analysis revealed that RCTs were disseminated earlier (median 79 days; IQR 52-131) when compared to observational studies (median = 144 days; IQR 69-206) (p = 0.003). Six papers were retracted from high impact journals; in which the average period till publication was 33 days. Retraction of papers occurred within 10-48 days. Expedited reviews, research approval and early publications of COVID-19 related pharmaceutical studies could have an impact on the quality of publications. However, the huge number of publications in short time creates confusion for readers during the early phases of the pandemic. Retraction of papers is alarming but ensures research integrity and correctness of scientific information. These abbreviated processes could affect patient care and public awareness. It is imperative to follow rapid but rigours ethical standards for research approval and peer-review process for publications during health pandemics.
    Keywords:  COVID-19 pandemic; pharmaceutical studies; publications; research ethics; retraction
    DOI:  https://doi.org/10.1177/00368504211016936
  35. J Med Internet Res. 2021 May 07.
       BACKGROUND: The COVID-19 pandemic highlighted the importance of rapid dissemination of scientific and medical discovery. Current platforms available to distribute scientific and clinical research data and information include preprint repositories and traditional peer-reviewed journal articles. Social media (SoMe) has now also emerged as a helpful platform to share discoveries in science and medicine.
    OBJECTIVE: This study analyzed activity on SoMe (specifically, Twitter) as it compared to the activity of article publications - in the form of preprints and peer-reviewed journals - related to COVID-19 and gastroenterology (GI) during the early stages of the COVID-19 pandemic.
    METHODS: Data from Twitter (Tweets, user data), preprint servers (Bio/MedRxiv)and PubMed (articles published) related to COVID-19 was collected and analyzed during the first 6 months of the pandemic, from December 2019 through May 2020. Global and regional geographic and gastrointestinal organ specific social media trends were compared to preprint and publication activity. Any relationships between Twitter activity and preprint articles published, as well as Twitter activity and PubMed articles published overall, by organ system and geographical location were identified using Spearman's rank-order correlation.
    RESULTS: Over the 6-month period, there were 73,079 tweets from 44,609 users, 7,164 journal article publications, and 4,702 preprint article publications. Twitter activity (number of Tweets) peaked during March while preprint and publication activity (number of articles published) peaked in April 2020. Overall, strong correlations were identified between the trends in activity of Twitter and both preprints and publications (p<0.001 for both). COVID-19 data across the 3 platforms mainly concentrated on pulmonology/critical care, but when looking at the field of GI, most tweets pertained to pancreatology, most publications focused on hepatology, and most preprints covered hepatology and luminal GI (LGI). Regarding GI subfields, there were significant positive associations between trends in Twitter activity and research for all topics (p=0.009 for LGI, p=0.006 for hepatology and IBD, p=0.007 for endoscopy), except pancreatology (p=0.2) - meaning that Twitter activity did not correlate to the same activity in publications. Finally, Twitter activity was highest in the US (7,331 tweets) whereas PubMed activity was highest in China (1,768 publications).
    CONCLUSIONS: The COVID-19 pandemic displayed the potential of SoMe as a vehicle for disseminating scientific information during a public health crisis. Sharing and spreading info on COVID-19 in a timely manner during this time was key, and SoMe, particularly Twitter, achieved that much faster. Future investigation could demonstrate how SoMe can be used to augment and promote scholarly activity especially as the world begins relying more and more on digital/virtual platforms. Scientists and clinicians should consider the use of SoMe in augmenting public awareness of their scholarly pursuits.
    DOI:  https://doi.org/10.2196/26956
  36. J Am Acad Orthop Surg Glob Res Rev. 2021 05 13. 5(5):
       BACKGROUND: The research gap year has become increasingly popular among medical students. It is also a well-known factor in consideration for orthopaedic surgery residency programs. Although medical students who participated in a research gap year typically enter residency with more research experience than their counterparts, it is unknown whether this translates to increased research productivity during residency compared with their peers. The purpose of this study was to investigate (1) whether residents who participated in a research gap year during medical school publish more peer-reviewed publications than their peers during residency, (2) whether residents who participated in a research gap year during medical school publish more first-author publications than their peers during residency, and (3) which applicant characteristics are associated with a greater number of peer-reviewed publications produced during residency.
    METHODS: The number of peer-reviewed journal publications before and during residency was determined by querying PubMed for 81 orthopaedic surgery residents at two academic institutions. Electronic residency application service applications and curriculum vitae were reviewed to evaluate the number of conference podiums and conference posters presented before residency and during residency. The research productivity of residents who participated in a research gap year during medical school was compared with that of residents who had not participated in a research gap year. Multivariate regression was done to determine predictors of publishing peer-reviewed journal publications during residency.
    RESULTS: Residents who participated in a research gap year during medical school produced more peer-reviewed journal publications during residency than those who did not (22.0 ± 20 versus 16.5 ± 20, P = 0.025). However, residents who participated in a research gap year did not produce more first-author publications compared with their peers (7.6 ± 10.0 versus 7.9 ± 7.0, P = 0.12). Residents who produced more publications before residency produced more publications while in residency (R = 0.363, P < 0.001). The United States Medical Licensing Examination step 1 score, medical school ranking, and sex were not associated with any difference in the number of journal publications produced during residency.
    CONCLUSION: A dedicated research year during medical school is associated with an increase in the number of peer-reviewed publications produced during residency. However, students who completed a research year did not publish more first-author publications than their peers. The number of publications before residency was a strong predictor of research output as a resident.
    DOI:  https://doi.org/10.5435/JAAOSGlobal-D-21-00061
  37. J Environ Sci (China). 2021 Jun;pii: S1001-0742(20)30494-0. [Epub ahead of print]104 53-68
      Constructed wetlands (CWs) have been introduced to and developed in China for environmental engineering over the most prosperous three decades (1990-2020). To study the origin, development process, and future trend of CWs, this review summarized a wide range of literatures between 1990 and 2020 by Chinese authors. Firstly, the publication number over years, research highlights, and the author contributions with the most published papers in this field were conducted through bibliometric analysis. Secondly, the most principal components of CWs, substrates and macrophytes were summarized and analyzed. Thirdly, the typical application cases from traditional CWs, pond systems to combined pond-wetland systems were presented. In China, CWs were predominately distributed in the east of the so-called 'Hu Huanyong Line'. Therefore CWs were limited by the socio-economic level and climatic conditions. It is unquestionable that the overall level of China's CWs has improved significantly, and one of the most prominent features has started towards the plural pattern development. There has been a trend of large-scale or low-cost CW application in the recent years. However, lifecycle research and management are required for better strategies in the future.
    Keywords:  Applications; Bibliometric analysis; Constructed wetlands; Future concerns and challenges; Macrophytes; Substrates
    DOI:  https://doi.org/10.1016/j.jes.2020.11.032
  38. PLoS One. 2021 ;16(5): e0248625
      The number of retracted articles has grown fast. However, the extent to which researchers and the public are made adequately aware of these retractions and how the media and social media respond to them remains unknown. Here, we aimed to evaluate the media and social media attention received by retracted articles and assess also the attention they receive post-retraction versus pre-retraction. We downloaded all records of retracted literature maintained by the Retraction Watch Database and originally published between January 1, 2010 to December 31, 2015. For all 3,008 retracted articles with a separate DOI for the original and its retraction, we downloaded the respective Altmetric Attention Score (AAS) (from Altmetric) and citation count (from Crossref), for the original article and its retraction notice on June 6, 2018. We also compared the AAS of a random sample of 572 retracted full journal articles available on PubMed to that of unretracted full articles matched from the same issue and journal. 1,687 (56.1%) of retracted research articles received some amount of Altmetric attention, and 165 (5.5%) were even considered popular (AAS>20). 31 (1.0%) of 2,953 with a record on Crossref received >100 citations by June 6, 2018. Popular articles received substantially more attention than their retraction, even after adjusting for attention received post-retraction (Median difference, 29; 95% CI, 17-61). Unreliable results were the most frequent reason for retraction of popular articles (32; 19%), while fake peer review was the most common reason (421; 15%) for the retraction of other articles. In comparison to matched articles, retracted articles tended to receive more Altmetric attention (23/31 matched groups; P-value, 0.01), even after adjusting for attention received post-retraction. Our findings reveal that retracted articles may receive high attention from media and social media and that for popular articles, pre-retraction attention far outweighs post-retraction attention.
    DOI:  https://doi.org/10.1371/journal.pone.0248625