bims-evares Biomed News
on Evaluation of research
Issue of 2020–08–09
33 papers selected by
Thomas Krichel, Open Library Society



  1. Jpn J Radiol. 2020 Aug 07.
       PURPOSE: Bibliometric analysis is a quantitative assessment of the academic literature in a particular field. The aim of our study was to characterize the 100 top-cited articles regarding transarterial chemoembolization (TACE) for the treatment of hepatocellular carcinoma (HCC).
    MATERIALS AND METHODS: The 'Web of Science' database was used to identify the leading articles regarding TACE for HCC. We determined the top 100 articles according to citations and performed an analysis on year of publication, authorship, department affiliation, publishing journal, institution and country of origin, subject matter and article type.
    RESULTS: The top-cited articles received between 92 and 2254 citations (median 283.4). The top 100 papers were published in 32 journals between 1983 and 2016. Cancer, Radiology and Hepatology published the most articles (n = 40). Internal medicine was the department affiliation of the first author in 49%. The country providing the most highly cited articles was Japan (n = 24).
    CONCLUSION: We performed an analysis of the 100 top-cited articles dealing with TACE for HCC, presenting a detailed list of the most influential and historically significant papers. Japan was the country that produced the most top-cited articles, highlighting its key contribution to this field of the literature.
    Keywords:  Bibliometrics; Citation analysis; Hepatocellular carcinoma; Transarterial chemoembolization
    DOI:  https://doi.org/10.1007/s11604-020-01028-x
  2. Hum Vaccin Immunother. 2020 Aug 05. 1-15
       INTRODUCTION: In low-income countries, Hepatitis E infection is a common cause of acute hepatitis. So far, only two recombinant vaccines (rHEV and HEV 239) have been developed against Hepatitis E virus (HEV). Of which HEV 239 is licensed in China, but is not yet available in any other country.
    OBJECTIVE: This study aims to discuss epidemiology, diagnosis, available vaccines for HEV, and provides an overview of 100 top-cited studies on HEV.
    METHODS: A bibliometric analysis was conducted on the topic "HEV" through a systematic search of the Web of Science. The keywords used were "Hepatitis E" and retrieved articles were assessed for number of attributes.
    RESULTS: The search returned a total of 3,235 publications, cited 95,858 times with h-index 129. The main finding for the 100 top-cited articles on HEV showed: number of authors ranging from 1 to 23, cited references range from 4 to 304, global citations score per year range from 6.61 to 175, and global citations score range from 148 to 791. Of the 100 top-cited studies, the authors who published most articles are Purcell (n = 18), Meng (n = 17), and Emerson (n = 15). Most The largest share of articles on HEV was contributed by United States of America (n = 49) with 12,795 citations. The National Institute of Allergy andInfectious Diseases was leading institute with greatest number of publications (n = 16), cited 3,950 times.
    CONCLUSIONS: The studies conducted on HEV have increased over time. The information presented would be very useful in decision making for policy makers providing health care, and for academicians in providing a reference point for future research.
    Keywords:  Hepatitis E; bibliometric analysis; epidemiology; vaccines
    DOI:  https://doi.org/10.1080/21645515.2020.1795458
  3. J Adv Nurs. 2020 Aug 07.
       AIM: This study aimed to identify and investigate the main characteristics of the top 100 most cited studies on conflict in published in nursing category in the Web of Science database using bibliometric and social network analysis methods.
    DESIGN: A retrospective bibliometric analysis was used.
    METHODS: The study data were obtained from the Web of Science (WoS) database. The top 100 studies with the highest number of citations were included in the study. The study data were analysed with Excel and SPSS and they were visualized with VOSviewer.
    RESULTS: It was concluded that the studies in the research were published in 38 different journals between 1974-2019 and they were conducted by 245 different authors from 24 different countries. It was further reported that the Journal of Advanced Nursing was the most productive journal and the USA was the most productive country. The most commonly used keywords were "nurse," "conflict," "nursing," "job satisfaction," "work-family conflict" and "ethical conflict."
    CONCLUSION: The issue of conflict is a growing field of scientific study for nursing researchers. The quality of researches will be certainly enhanced in future with the studies published in journals with high impact factors.
    IMPACT: The research of the top 100 most cited paper is a new and innovative bibliometric approach to understand nursing literature. There is very little information about the development, structure and characteristics of the existing mass of knowledge on conflict in nursing studies. The study findings establish a basis of information for planning further studies and providing guidance. In addition, this study provides researchers, scientific journals, institutions and countries with an opportunity to assess and compare their own performance in conflict literature in nursing studies. However, the fact that the most cited studies in the field of conflict in nursing is in demand by journals with high impact factor is a source of motivation for researchers studying in this field.
    Keywords:  bibliometric analysis; bibliometry; conflict; nurse; nursing; social network analysis
    DOI:  https://doi.org/10.1111/jan.14463
  4. Tuberk Toraks. 2020 Jul;68(2): 81-95
       Introduction: In this study, made an analysis of the top 100 most-cited articles about respiratory system from Turkey, which was published in Science Citation Index (SCI) and SCI Expanded (SCIE) index.
    Materials and Methods: In Web of Science (WoS) advanced search of the database of "core collection" [v.5.31]; It was written to "CU=TURKEY AND SU=RESPIRATORY SYSTEM" and reached articles from Turkey published in SCI and SCIE indexes until 13.11.2019. The journal in which it was published, the impact factor of the journals, citation counts and the average of the annual citations of the publication of the first 100 articles were found.
    Result: From 1975 to 13 November 2019, the total number of publications in the field of respiratory system by the scientists of our country was 5828. The total number of citations to these articles is 48.708 (with subtracting the self citations it was 46.972). The average of citations per publication in our country is 8.36. The total number of citations for the first 100 articles was 12.374. The most cited article with 309 citations is; "The Arg753Gln Polymorphism of the Human Toll-like Receptor 2 Gene in Tuberculosis Disease" written by Ogus AC, et al. It was published in "European Respiratory Journal". Until 13.11.2019 in WoS database related to respiratory system; It has been published 494.974 articles. Published articles from Turkey is 1.17% of the total articles about respiratory system.
    Conclusions: Although there are our studies have been published in journals with high impact factors, our contribution to the literature still seems limited.
    DOI:  https://doi.org/10.5578/tt.69387
  5. Neuropsychol Rehabil. 2020 Aug 02. 1-18
      Purpose: This paper aims to present a bibliometric analysis of scientific documents in the field of traumatic brain injury rehabilitation. Methods: Web of Science was used to collect bibliographic data of traumatic brain injury rehabilitation documents from 1983 until the end of 2017. Results: Of a total of 6069 documents retrieved, 78.2% were journal articles. The average annual growth of the documents as of the year 2000 was 9.4%. The most frequent subject categories in this field were Rehabilitation, Neurosciences and Neurology, Sport Sciences, Psychology, and General and Internal Medicine. The most active journal was Brain Injury. More than 50% of the documents were published in 10 journals. The most prolific and impactful institutions were from the USA, Australia and Canada. Traumatic brain injury, rehabilitation, brain injury, stroke and outcome were the most commonly used keywords. Mild traumatic brain injury and concussion were the topics receiving attention in recent years. Conclusion: Traumatic brain injury rehabilitation is a young and constantly growing field. Since the late 1990s, traumatic brain injury rehabilitation documents published yearly comprised about 3-4% of all rehabilitation documents. It was shown that review papers and proceedings have more impact than journal articles, and collaborative papers receive more citations. It was also revealed that knowledge does not become obsolete rapidly in this field.
    Keywords:  Bibliometrics; Keyword analysis; Rehabilitation; Scientometrics; TBI; Traumatic brain injury
    DOI:  https://doi.org/10.1080/09602011.2020.1796714
  6. Am J Emerg Med. 2020 May 17. pii: S0735-6757(20)30376-4. [Epub ahead of print]38(9): 1754-1759
       INTRODUCTION: Over the past few decades, the incidence of Rhabdomyolysis (RM) has significantly increased. The prognosis is substantially worse if renal failure develops. Many problems remain to be addressed regarding the pathogenesis, prevention, and treatment of RM. The purpose of this study was to identify and characterize the top 100 most cited publications regarding rhabdomyolysis (RM) by performing a bibliometric analysis.
    METHODS: Publications focusing on RM were identified from the Science Citation Index-Expanded (SCI-E) of the Web of Science Core Collection (WoSCC). Bibliographic information was collected, including year of publication, authorship, publishing journals, institution, country of origin and keywords. CiteSpace V5.6.R2 and the Online Analysis Platform of Literature Metrology were used for descriptive analysis.
    RESULTS: The 100 most cited articles were published between 1995 and 2016, with citation numbers ranging from 116 to 904. The United States (60) has been the largest contributor to RM research. Hartford Hospital and University of Texas were found to be the most productive institutions, with five articles each. Thompson, PD, who authored six articles, was the most productive author. The American Journal of Cardiology published the most articles (5), followed by the New England Journal of Medicine (4). The top three co-cited journals were the New England Journal of Medicine (74), Lancet (59) and JAMA (54).
    CONCLUSIONS: This study provides valuable information on the study of RM. These findings may be used to guide clinical decision-making and identify new research fields.
    Keywords:  Acute kidney injury; Bibliometric analysis; Rhabdomyolysis
    DOI:  https://doi.org/10.1016/j.ajem.2020.05.031
  7. Cell Tissue Bank. 2020 Aug 06.
      Many articles involving human brain banks have been published. Bibliometric analysis can determine the history of the development of research and future research trends in a specific field. Three independent researchers retrieved and reviewed articles from the Web of Science database using the following strategy: "TS = (((brain OR cerebral) AND (bank* OR biobank*)) OR brainbank*)." The top 100 most-cited articles were identified and listed in descending order by total citations. Web of Science was used to identify ten recent articles describing bank construction. GeenMedical ( https://www.geenmedical.com/ ) was used to identify ten recent articles from journals with an impact factor (IF) > 20. The top 100 most-cited articles citing human brain banks were published between 1991 and 2017. Fifty-two percent of the articles focused on a specific type of neurodegenerative disease, and 16% discussed the construction and development of human brain banks. Articles using brain tissue had more total and annual citations than those on bank construction. Ten articles with high IFs were published from 2017 to 2019, and they were primarily studies using novel research techniques such RNA sequencing and genome-wide association studies. Most studies were published in journals specializing in neurology or neuroscience such as Movement Disorders (10%), and had been conducted in the United States (52%) by neurologists (62%). The top 100 most-cited articles and recent publications citing human brain banks and their bibliometric characteristics were identified and analyzed, which may serve as a useful reference and pave the way for further research.
    Keywords:  Bibliometric analysis; Citations; Human brain bank; Top 100 most-cited articles; Web of science
    DOI:  https://doi.org/10.1007/s10561-020-09849-w
  8. Front Psychol. 2020 ;11 1512
      Emotions are considered a fundamental aspect of sport scenarios, and within sports, consumer behavior is a very popular area of research in the sport management field. Thus, in recent years, there has been a growing interest for sport managers regarding the role that emotions play in sport consumer behavior. Thus, the aim of this paper is to provide an overview of the academic research on emotions in the sport management field using two techniques: a bibliometric performance analysis and a graphic mapping of the references in this field. This analysis focuses on authors, journals, papers, institutions and countries. Bibliometric indicators including the h-index measure, productivity and the number of citations were used to perform the performance analysis. Then, VOSviewer software was used to perform co-citation, bibliographic coupling and co-occurrence of keyword analysis (mapping analysis). The results of both types of analysis are consistent, with the United States being the most influential country in emotions in sport management research because the main authors and institutions in this research field belong to this country. The overall results indicate that the literature on this research topic has grown significantly in recent years in all scientific disciplines; however, the research topic is incipient, and therefore, the number of articles is still limited. Thus, this research presents the key aspects in the topic of emotions in sport management that could be helpful for researchers and policy makers in the field of sport management to make future decisions.
    Keywords:  bibliometric analysis; emotions; h-index; mapping science; sport management
    DOI:  https://doi.org/10.3389/fpsyg.2020.01512
  9. Int J Environ Res Public Health. 2020 Aug 04. pii: E5607. [Epub ahead of print]17(15):
      Intimate partner violence (IPV) is a worldwide public health problem. Here, a bibliometric analysis is performed to evaluate the publications in the Intimate Partner Violence (IPV) field from 2000 to 2019 based on the Science Citation Index (SCI) Expanded and the Social Sciences Citation Index (SSCI) databases. This work presents a detailed overview of IPV from aspects of types of articles, citations, h-indices, languages, years, journals, institutions, countries, and author keywords. The results show that the USA takes the leading position in this research field, followed by Canada and the U.K. The University of North Carolina has the most publications and Harvard University has the first place in terms of h-index. The London School of Hygiene and Tropical Medicine leads the list of average citations per paper. The Journal of Interpersonal Violence, Journal of Family Violence and Violence Against Women are the top three most productive journals in this field, and Psychology is the most frequently used subject category. Keywords analysis indicates that, in recent years, most research focuses on the research fields of "child abuse", "pregnancy", "HIV", "dating violence", "gender-based violence" and "adolescents".
    Keywords:  HIV; bibilometric; intimate partner violence; keywords analysis; violence
    DOI:  https://doi.org/10.3390/ijerph17155607
  10. BMC Infect Dis. 2020 Aug 01. 20(1): 561
       BACKGROUND: The novel coronavirus, named as 2019-nCoV or coronavirus disease 2019 (COVID-19), has recently appeared in China and has spread worldwide, presenting a health threat to the global community. Therefore, it is important to understand the global scientific output of COVID-19 research during the early stage of the outbreak. Thus, to track the current hotspots, and highlight future directions, we performed a bibliometric analysis to obtain an approximate scenario of COVID-19 to date.
    METHODS: Relevant studies to COVID-19 were obtained from the Scopus database during the early stage of the outbreak. We then analysed the data by using well-established bibliometric indices: document type, country, collaboration patterns, affiliation, journal name, and citation patterns. VOSviewer was applied to map and determine hot topics in this field.
    RESULTS: The bibliometric analysis indicated that there were 19,044 publications on Scopus published on COVID-19 during the early stage of the outbreak (December 2019 up until June 19, 2020). Of all these publications, 9140 (48.0%) were articles; 4192 (22.0%) were letters; 1797 (9.4%) were reviews; 1754 (9.2%) were editorials; 1728 (9.1%) were notes; and 433 (2.3%) were others. The USA published the largest number of publications on COVID-19 (4479; 23.4%), followed by China (3310; 17.4%), Italy, (2314; 12.2%), and the UK (1981; 10.4%). British Medical Journal was the most productive. The Huazhong University of Science and Technology, Tongji Medical, and Harvard Medical School were the institutions that published the largest number of COVID-19 research. The most prevalent topics of research in COVID-19 include "clinical features studies", "pathological findings and therapeutic design", "care facilities preparation and infection control", and "maternal, perinatal and neonatal outcomes".
    CONCLUSIONS: This bibliometric study may reflect rapidly emerging topics on COVID-19 research, where substantial research activity has already begun extensively during the early stage of the outbreak. The findings reported here shed new light on the major progress in the near future for hot topics on COVID-19 research including clinical features studies, pathological findings and therapeutic design, care facilities preparation and infection control, and maternal, perinatal and neonatal outcomes.
    Keywords:  2019-nCoV; Bibliometric; COVID-19; Novel coronavirus; Scopus
    DOI:  https://doi.org/10.1186/s12879-020-05293-z
  11. Acta Inform Med. 2020 Jun;28(2): 84-93
       Introduction: Certain methodological principles should be inexcusably followed when designing clinical or observational research to avoid bias and presentation of results that do not reflect the truth about the phenomenon that is the object of the study.
    Aim: The aim of this study was to compare the methodological quality of clinical trials and observational studies published in medical journals from ex-Yugoslav countries indexed in Pubmed/MEDLINE.
    Methods: Clinical studies published in medical journals of ex-Yugoslav countries were retrieved from the Pubmed/MEDLINE database, and the sample for analysis was randomly chosen from the retrieved publications. The rate of the most common errors in the design of clinical/observational studies was established by a careful reading of the sampled publications and their checking against predefined criteria.
    Results: The studies published in two countries that are now member states of the European Union (Slovenia and Croatia) have significantly higher citation rates, impact factor, and methodological quality scores than studies from other ex-Yugoslav countries. While publications from Croatia show clear improvement trend throughout the last two decades, which is visible also in the last 10 years in Slovenia and Bosnia and Herzegovina, quality of clinical research published in journals from Serbia was stagnating in the same period.
    Conclusions: There are significant differences in methodological quality and scientometric characteristics of clinical research published in medical journals of ex-Yugoslav countries that could be mitigated by more intensive training of clinical researchers in statistics and research design, as well as by more rigorous editorial practices.
    Keywords:  Clinical studies; Methodological errors; Research design; Statistical errors
    DOI:  https://doi.org/10.5455/aim.2020.28.84-93
  12. Int J Environ Res Public Health. 2020 Aug 05. pii: E5639. [Epub ahead of print]17(16):
      Microplastics (MPs) have generated worldwide attention due to their global distribution in the environment, and their potential harmful effects on human and animal health. To analyze MPs-related scientific publications from a global point of view, we created a bibliometric profile, by searching the Web of Science Core Collection database for the topic "microplastic* or (micro near/1 plastic*)", in publications dated from 2004 to 2019. The results revealed an increasing trend in publication output, and identified contributions of different countries and their collaborations, as well as influential authors and productive journals in the field of MPs research. Using co-citation network analysis in VOSviewer, we mined cited references for knowledge bases about analytical methods, potential sources and spatial distributions of MPs, the impacts of MPs on organisms, and the interaction of MPs with contaminants, as well as microorganisms. We also identified four global hotspots for MPs related research, using author keywords co-occurrence network analysis of all extracted publications, as well as Essential Science Indicators highly cited papers from Clarivate Analytics. Results of this study provide a valuable reference for ongoing MPs-related research, which may be of intrigue and awesome noteworthiness for relevant researchers.
    Keywords:  VOSviewer software; bibliometric; microplastics; network analysis; research hotspots
    DOI:  https://doi.org/10.3390/ijerph17165639
  13. Mar Pollut Bull. 2020 Sep;pii: S0025-326X(20)30550-6. [Epub ahead of print]158 111432
      This paper presents the research landscape on microplastics and nanoplastics (M/NPs) in global food webs based on a bibliometric analysis of 330 publications published in 2009-2019 extracted from Web of Science. The publications increased tremendously since 2013. Marine Pollution Bulletin is one of the top productive journals for this topic. The publication landscape related to M/NPs in global food webs, as interdisciplinary research, is highly dependent on the funding availability. The high productivities of England, China, USA and European countries are attributed to the funding from the agencies at regional or national levels. Keyword analysis reveals the shift of research hotspots from investigations on M/NPs absorbed by various organisms in the ecosystems to studies on the trophic transfer of M/NPs and sorbed contaminants in the food webs and their associated adverse impacts. Funding agencies play important roles in leading the future development of this topic.
    Keywords:  Ecological Corona; Marine ecosystem; Persistent organic pollutants; Terrestrial ecosystem; Trophic transfer
    DOI:  https://doi.org/10.1016/j.marpolbul.2020.111432
  14. PLoS One. 2020 ;15(8): e0236327
      Maximising research productivity is a major focus for universities world-wide. Graduate research programs are an important driver of research outputs. Choosing students with the greatest likelihood of success is considered a key part of improving research outcomes. There has been little empirical investigation of what factors drive the outcomes from a student's PhD and whether ranking procedures are effective in student selection. Here we show that, the research environment had a decisive influence: students who conducted research in one of the University's priority research areas and who had experienced, research-intensive, supervisors had significantly better outcomes from their PhD in terms of number of manuscripts published, citations, average impact factor of journals published in, and reduced attrition rates. In contrast, students' previous academic outcomes and research training was unrelated to outcomes. Furthermore, students who received a scholarship to support their studies generated significantly more publications in higher impact journals, their work was cited more often and they were less likely to withdraw from their PhD. The findings suggest that experienced supervisors researching in a priority research area facilitate PhD student productivity. The findings question the utility of assigning PhD scholarships solely on the basis of student academic merit, once minimum entry requirements are met. Given that citations, publication numbers and publications in higher ranked journals drive university rankings, and that publications from PhD student contribute approximately one-third of all research outputs from universities, strengthening research infrastructure and supervision teams may be more important considerations for maximising the contribution of PhD students to a university's international standing.
    DOI:  https://doi.org/10.1371/journal.pone.0236327
  15. PLoS One. 2020 ;15(8): e0233455
      This study focuses on the use and users of Finnish social science research data archive. Study is based on enriched user data of the archive from years 2015-2018. Study investigates the number and type of downloaded datasets, the number of citations for data, the demographics of data downloaders and the purposes data are downloaded for. Datasets were downloaded from the archive 10346 times. Majority of the downloaded datasets are quantitative. Quantitative datasets are also more often cited, but the number of citations vary and does not always correlate with the number of downloads. Use of the archive varies by user's country, organization, and discipline. Datasets from the archive were downloaded most often for study work, bachelor's and master's theses, and research purposes. It is likely that reusing research data will increase in the near future as more data will become available, scholars are more informed about research data management, and data citation practices are established.
    DOI:  https://doi.org/10.1371/journal.pone.0233455
  16. J Voice. 2020 Aug 01. pii: S0892-1997(20)30241-1. [Epub ahead of print]
       OBJECTIVE: To verify the relationship between self-regulation and voice behavior according to national and international literature.
    METHODS: A literature survey was performed using the PubMed, LILACS, and SciELO databases. The search terms used were the following: self-regulation, self-control, combined with voice, voice disorders, and dysphonia, in Portuguese, English, and Spanish. Articles that addressed self-regulation and voice behavior or voice disorders published in English, Spanish, or Portuguese were included, without restriction of date. The variables preselected for the data organization were authors, database, country, impact factor, journal, type of study, sample size, sample characteristics, methods for data collection, group comparison, objective, and outcome.
    RESULTS: A total of 10,176 articles were identified in the databases, of which 10 were selected based on title, read in full, and kept for data analysis. The studies were found predominantly in American journals and were published between 2013 and 2019. The United States published most articles, and the predominant methodological aspect was observational and cross-sectional.
    CONCLUSION: Despite the small number of articles, the studies analyzed can show self-regulation as an important factor in vocal behavior and call attention to its performance in voice disorders.
    Keywords:  Behavior–Mental disorders–Self-control–Voice–Voice disorders–Dysphonia
    DOI:  https://doi.org/10.1016/j.jvoice.2020.06.023
  17. Front Psychol. 2020 ;11 1486
      Major depressive disorder (MDD) is the most severe depression type and one of the leading causes of morbidity worldwide. Animal models are widely used to understand MDD etiology, pathogenesis, and treatment, but the efficacy of this research for patients has barely been systematically evaluated. Such evaluation is important given the resource consumption and ethical concerns incurred by animal use. We used the citation tracking facilities within Web of Science and Scopus to locate citations of original research papers on rats related to MDD published prior to 2013-to allow adequate time for citations-identified in PubMed and Scopus by relevant search terms. Resulting citations were thematically coded in eight categories, and descriptive statistics were calculated. 178 publications describing relevant rat studies were identified. They were cited 8,712 times. More than half (4,633) of their citations were by other animal studies. 794 (less than 10%) were by human medical papers. Citation analysis indicates that rat model research has contributed very little to the contemporary clinical understanding of MDD. This suggests a misuse of limited funding hence supporting a change in allocation of research and development funds targeting this disorder to maximise benefits for patients.
    Keywords:  animal models; animal use alternatives; citation analysis; major depressive disorder; rat
    DOI:  https://doi.org/10.3389/fpsyg.2020.01486
  18. J Foot Ankle Surg. 2020 Jul 31. pii: S1067-2516(20)30175-7. [Epub ahead of print]
      The number of women in podiatric medicine and surgery has increased steadily over the past 4 decades; however, there appears to be a large and continued gender gap with respect to representation in academic medicine and other positions of power. National and state level organizational data were obtained from multiple podiatry professional societies to evaluate the rate at which women achieved leadership roles within the podiatric profession over time. A secondary questionnaire was also developed and electronically mailed to 8684 doctors of podiatric medicine to help capture additional leadership information and to provide further insight into the trends observed. The response rate was 26% (2276/8684). Female representation in academia, research/publications, most leadership positions, and board certifications has increased over time, but at a slower rate than the number of women entering the profession. We observed a decreasing trend of females completing fellowships, speaking at national meetings, becoming residency directors, and receiving American College of Foot and Ankle Surgeons- and American Podiatric Medical Association-sponsored grants/awards. Based on the survey results, female podiatric physicians were more likely to be single, have fewer children, spend more time in a clinical setting, be less satisfied with work, and experience higher work stress levels than their male colleagues. Of the female respondents, 73% described experiencing gender discrimination at some point in their career, and 42% reported experiencing sexual harassment, compared with only 6% and 5% of men, respectively. There continues to be a gender gap in leadership roles, which may be explained partially by work/life balance issues, gender discrimination, and other issues.
    Keywords:  authorship; board certification; equality; gender trends; leadership; podiatry; women; women in surgery
    DOI:  https://doi.org/10.1053/j.jfas.2020.05.002
  19. Int J Mol Sci. 2020 Aug 04. pii: E5576. [Epub ahead of print]21(15):
      This article presents a study of the literature of chemoinformatics, updating and building upon an analogous bibliometric investigation that was published in 2008. Data on outputs in the field, and citations to those outputs, were obtained by means of topic searches of the Web of Science Core Collection. The searches demonstrate that chemoinformatics is by now a well-defined sub-discipline of chemistry, and one that forms an essential part of the chemical educational curriculum. There are three core journals for the subject: The Journal of Chemical Information and Modeling, the Journal of Cheminformatics, and Molecular Informatics, and, having established itself, chemoinformatics is now starting to export knowledge to disciplines outside of chemistry.
    Keywords:  bibliometrics; cheminformatics; chemoinformatics; scientometrics
    DOI:  https://doi.org/10.3390/ijms21155576
  20. World J Clin Cases. 2020 Jul 06. 8(13): 2817-2832
       BACKGROUND: Gut microbiota is an emerging field of research, with related research having breakthrough development in the past 15 years. Bibliometric analysis can be applied to analyze the evolutionary trends and emerging hotspots in this field.
    AIM: To study the subject trends and knowledge structures of gut microbiota related research fields from 2004 to 2018.
    METHODS: The literature data on gut microbiota were identified and downloaded from the PubMed database. Through biclustering analysis, strategic diagrams, and social network analysis diagrams, the main trend and knowledge structure of research fields concerning gut microbiota were analyzed to obtain and compare the research hotspots in each period.
    RESULTS: According to the strategic coordinates and social relationship network map, Clostridium Infections/microbiology, Clostridium Infections/therapy, RNA, Ribosomal, 16S/genetics, Microbiota/genetics, Microbiota/immunology, Dysbiosis/immunology, Infla-mmation/immunology, Fecal Microbiota Transplantation/methods, Fecal Microbiota Transplantation can be used as an emerging research hotspot in the past 5 years (2014-2018).
    CONCLUSION: Some subjects were not yet fully studied according to the strategic coordinates; and the emerging hotspots in the social network map can be considered as directions of future research.
    Keywords:  Bibliometric analysis; Co-word analysis; Gut microbiota; Social relationship network analysis; Strategic coordinates
    DOI:  https://doi.org/10.12998/wjcc.v8.i13.2817
  21. Ann Surg. 2020 Jul 24.
       OBJECTIVE: The aim of this study was to assess the contemporary trends in National Institutes of Health (NIH) grants awarded to surgical investigators, including potential disparities.
    BACKGROUND: The NIH remains the primary public funding source for surgical research in the United States; however, the patterns for grants and grantees are poorly understood.
    METHODS: NIH RePORTER was queried for new grants (R01, -03, -21) awarded to Departments of Surgery (DoS). Principal investigators' (PIs) data were extracted from publicly available information from their institutions' websites and/or professional social media accounts.
    RESULTS: The NIH awarded 1101 new grants (total: $389,006,782; median: $313,030) between 2008 and 2018. Funding to DoS has doubled in the last 10 years ($22,983,500-2008 to $49,446,076-2018). Midwest/Southeast institutions and surgical oncologists accounted for majority of the grants (31.9% and 24.5%, respectively). Only 24.7% of the projects were led by female PIs, who were predominantly nonphysician PhD scientists (52% vs 37.7% PhD-only male PIs; P = 0.002). During this time, there was a significant increase from 12.4% to 31.7% in grants awarded to PIs with >15 years of experience. These grants were associated with 8215 publications; however, only 13.2% were published in high-impact journals (impact factor ≥10). 4.4% of the grants resulted in patents, and these were associated with higher award amounts ($345,801 vs $311,350; P = 0.030). On multivariate analysis, combined MD/PhD degree [odds ratio (OR) 5.98; 95% confidence interval (CI) 2.18-16.39; P < 0.001] was associated with improved odds of patent creation; conversely, practicing surgeon PIs affected patent creation negatively (OR 0.31; 95% CI 0.11-0.85; P = 0.024).
    CONCLUSION: In the last decade, a greater proportion of NIH grants in DoS were awarded to more experienced investigators. Disparities exist among grantees, and female investigators are underrepresented, especially among practicing surgeons.
    DOI:  https://doi.org/10.1097/SLA.0000000000004206
  22. Ann Surg Oncol. 2020 Aug 03.
       BACKGROUND: Our study sought to evaluate gender representation and the impact of gender on the large volume of research presented at The American Society of Breast Surgeons (ASBrS) Annual Meeting, the largest breast surgery meeting in the United States.
    METHODS: Publicly available ASBrS meeting programs and proceedings from 2009 to 2019 were reviewed to ascertain proportions of female engagement in society positions, contributions to scientific sessions, and subsequent manuscript publications. Trend analyses for temporal changes in gender representation and univariate tests of associations between authorship gender and publication success were performed.
    RESULTS: Women comprised 44.8% of members of the board of directors, 41.7% of committee chairs, and 54.8% of committee members. There were significant annual increased proportions of female committee members (3.2% per year, p = 0.01) and chairs (6.0% per year, p = 0.03). Women represented > 50% of all speakership positions, except keynote (42.2%). For oral, quickshot, and poster scientific presentations, > 70% of first authors and > 60% of senior authors were women. The meeting-related publication rate with female senior authorship was higher than that with male senior authorship (41.0% vs. 36.3%, p = 0.04).
    CONCLUSIONS: Although female surgeons remain a minority at most conferences, women have represented the majority of participants in committees, speakership, and scientific presentations at the ASBrS Annual Meeting over the past 10 years. The glass ceiling in breast surgery has been shattered, but efforts to improve gender equity must continue, not only in breast surgery, but all surgical specialties.
    DOI:  https://doi.org/10.1245/s10434-020-08899-4
  23. Australas J Dermatol. 2020 Aug 05.
       BACKGROUND: Psoriasis is a relatively common inflammatory skin disease with systemic implications. Psoriasis data seem to arise from a select number of countries, while other areas in the world with different genetics and ethnicities, especially Arab countries have a questionable input.
    AIM: This study aims to quantitatively assess Arab countries contributions in psoriasis research.
    METHODS: The number of publications related to psoriasis for each of the 22 Arab countries was found on PubMed for every year between 2004 and 2019, and then, the total for each country was normalised according to three parameters: average population, Gross Domestic Product and psoriasis disability-adjusted life years. In addition, the number of psoriasis articles was also retrieved for 2 other groups: South America and Far East Asia, for comparison.
    RESULTS: Only 1.53% of all psoriasis research published between 2004 and 2019 originates from Arab countries (vs. 2.06% from South American countries and 13.2% from Far East Asian countries), and psoriasis articles make up only 0.15% of the total publications from Arab countries (vs. 0.10% for both South American and Far East Asian countries). Egypt scored the highest number of psoriasis-related articles and accounted on its own for almost half the number of psoriasis publications (47.9%) from Arab countries. When normalised according to the 3 parameters, other Arab countries also rose to prominence; Kuwait had the highest number of publications per million persons, and Tunisia had the highest number of publications per GDP. However, Egypt ranked once again first as having the highest number of publications per 1% psoriasis-related DALY. Among the three parameters, the average population size proved to be the most strongly correlated with the number of psoriasis publications in a given country.
    CONCLUSION: There is an incontestable need for more research related to psoriasis in Arab countries as the numbers are still very low reflecting many difficulties standing In the way of research in general in the Arab world.
    Keywords:  Arab world; bibliometric analysis; dermatology; psoriasis; research activity
    DOI:  https://doi.org/10.1111/ajd.13407
  24. Front Psychol. 2020 ;11 1557
      In recent years, the study of women entrepreneurship has experienced great growth, gaining a broad consensus among academics and contributing above all to understanding all those factors that explain the difficulty of women in undertaking an entrepreneurial career. This document tries to contribute to the field of study, thanks to a systematic analysis through the publications present in the topic. For this purpose, 2,848 peer-reviewed articles were analyzed, published between 1950 and 2019, using the Scopus database (SCImago Research Group). Through the use of a series of bibliometric indicators it was possible to define the current state of research on the international scene. The analysis revealed that it is a multidisciplinary field of study and that has started to expand further since 2006, culminating in 2019, which makes it become a current and valid object of study. The analysis of the clusters allowed to isolate 6 different lines of research in which emerged, on the one hand, the importance of entrepreneurial education, social entrepreneurship and the socio-cultural context of reference (e.g., culture, family, and institutional support) as tools to overcome the gender gap, on the other, the importance that women entrepreneurship assumes in the economic growth of the country (especially in developing economies), promoting social inclusion and combating poverty and discrimination. The study presents an important contribution to reflect on current policies and to outline future lines of investigation.
    Keywords:  barriers; economic development; entrepreneurship; female entrepreneurship; gender gap; literature review; women; work-family balance
    DOI:  https://doi.org/10.3389/fpsyg.2020.01557
  25. Surgery. 2020 Jul 31. pii: S0039-6060(20)30379-2. [Epub ahead of print]
       BACKGROUND: Advanced clinical fellowships are important for training surgeons with a niche expertise. Whether this additional training impacts future academic achievement, however, remains unknown. Here, we investigated the impact of advanced fellowship training on research productivity and career advancement among active, academic cardiac surgeons. We hypothesized that advanced fellowships do not significantly boost future academic achievement.
    METHODS: Using online sources (eg, department webpages, CTSNet, Scopus, Grantome), we studied adult cardiac surgeons who are current faculty at accredited United States cardiothoracic surgery training programs, and who have practiced only at United States academic centers since 1986 (n = 227). Publicly available data regarding career advancement, research productivity, and grant funding were collected. Data are expressed as counts or medians.
    RESULTS: In our study, 78 (34.4%) surgeons completed an advanced clinical fellowship, and 149 (65.6%) did not. Surgeons who pursued an advanced fellowship spent more time focused on surgical training (P < .0001), and those who did not were more likely to have completed a dedicated research fellowship (P = .0482). Both groups exhibited similar cumulative total publications (P = .6862), H-index (P = .6232), frequency of National Institutes of Health grant funding (P = .8708), and time to achieve full professor rank (P = .7099). After stratification by current academic rank, or by whether surgeons pursued a dedicated research fellowship, completion of an advanced clinical fellowship was not associated with increased research productivity or accelerated career advancement.
    CONCLUSION: Academic adult cardiac surgeons who pursue advanced clinical fellowships exhibit similar research productivity and similar career advancement as those who do not pursue additional clinical training.
    DOI:  https://doi.org/10.1016/j.surg.2020.06.016
  26. Minerva. 2020 ;58(3): 343-365
      This article compares the career trajectories and mobility patterns of Nobel Laureates in economics with those of highly cited sociologists to evaluate a theory advanced by Richard Whitley that postulates a nexus between the overall intellectual structure of a discipline and the composition of its elite. The theory predicts that the most eminent scholars in internally fragmented disciplines such as sociology will vary in their departmental affiliations and academic career paths, while disciplines such as economics with strong linkages between specialties and shared standards of excellence will be dominated by a more homogeneous elite. The comparison provides strong empirical evidence in favor of Whitley's theory. The careers of the most eminent economists are closely tied to the top five departments of the discipline, whereas the career pathways to eminence in sociology are largely unpredictable.
    Keywords:  Academic careers; Academic elites; Elite networks; Nobel Laureates; Sequence analysis
    DOI:  https://doi.org/10.1007/s11024-020-09399-1
  27. Infect Disord Drug Targets. 2020 Aug 04.
       BACKGROUND: Trichomoniasis is a sexually transmitted disease (STD) prevalent in different parts of the world. The present study was designed to evaluate the scientific output and collaboration of researchers worldwide on trichomoniasis.
    METHODS: In the present scientometric research, all papers conducted on Trichomonas vaginalis (T. vaginalis) published in the time period of 1922 to 2018 were extracted from the Scopus database and evaluated according to the aims of the research, using scientometric software.
    RESULTS: The results of this search strategy were the retrieval of 12,596 scientific papers authored by a total of 28,822 people during 97 years (1922-2018). Research in this field have encountered success and failure over the years. The first article on trichomoniasis at the Scopus database was published by Musgrave W.E. (1922) in the "Journal of the American Medical Association". Most papers on this subject (352) were published in 2013; and the years 2017 and 2016 are ranked second and third. Researchers from the US Centers for Disease Control and Prevention have the highest number of papers in this field (210). Alderete J.F. with 111 papers is the most active researcher on trichomoniasis in Scopus. Also, researchers from the US ranked the first with 3,236 papers. In Iran, by the end of 2018, 138 papers on trichomoniasis have been registered in Scopus, which accounts for only one percent of the world's science production in this field.
    DISCUSSION: The results following about one century indicated that number of publications on T. vaginalis is growing and that there is a high level of collaboration among researchers in this field. Moreover, many countries have collaborated internationally on trichomoniasis research with the US as the leading country.
    Keywords:  Scopus; T. vaginalis; Trichomoniasis; bibliometric; scientific collaboration; sexually transmitted disease
    DOI:  https://doi.org/10.2174/1871526520666200804161110
  28. Front Psychiatry. 2020 ;11 647
       Background: Antidepressant treatment is one of the most effective ways of relieving or curing depressive symptoms in patients with major depressive disorder (MDD). Although many studies have explored the efficacy, tolerability, adverse reactions, and functional mechanism of the disease, there has been no systematic evaluation of the relevant results in this field.
    Aim: This paper aims to analyze the theme trends and knowledge structure of drug therapy studies on MDD since the 21st century by employing bibliometric analysis.
    Methods: Literature published in PubMed and related to drug therapy studies on MDD were retrieved between 2001 and 2018 in 6-year increments. After extracting major Medical Subject Headings (MeSH) terms/MeSH subheadings, bi-clustering analysis, social network analysis, and strategic diagrams were employed to complete bibliometric analysis.
    Results: Overall, 1,577, 2,680, 2,848 relevant research articles were retrieved for the periods during 2001-2006, 2007-2012, and 2013-2018, respectively. In line with strategic diagrams, the main undeveloped and peripheral theme clusters during 2001-2006 were functional mechanisms of antidepressants in pathophysiology, neuroendocrinology and neural biochemistry. These themes were replaced during 2007-2012 by clinical efficacy and influencing factors of antidepressants with or without psychotherapy, mechanisms of adverse reactions of antidepressants, and predictive studies of clinical therapeutic effects of antidepressants based on brain imaging. During 2013-2018 application and evaluation of new antidepressant agents, early identification and prevention of suicide of patients with MDD, as well as genetic- or bio-markers affecting the response and efficacy of antidepressants were the primary themes. Based on social network analyses, emerging hotspots, such as antidepressive agents, second-generation/adverse effects, depressive disorder, major/metabolism, psychotherapy/methods, and brain/drug effects could be identified during 2007-2012 and 2013-2018.
    Conclusions: These undeveloped theme clusters and emerging hotspots can be helpful for researchers to clarify the current status of their respective fields and future trends, and to generate novel ideas that may launch new research directions.
    Keywords:  bibliometric analysis; co-occurrence analysis; drug therapy; major depressive disorder; social network analysis; strategic diagram
    DOI:  https://doi.org/10.3389/fpsyt.2020.00647
  29. J Gen Fam Med. 2020 Jul;21(4): 119-126
       Backgrounds: The CONSORT for Abstracts checklist published in 2008 recommends that authors report effect size for their studies. Meanwhile, the FDA strongly recommends reporting both ratio and difference measures. However, the measures of effect used in recent clinical trial reports remain unknown. This study is aimed to reveal trends regarding the measures of effect of interventions described in abstracts of recent randomized controlled trials (RCTs) in leading journals.
    Methods: A bibliometric analysis of data was obtained by electronic searches. Human RCTs published in 2016 in the following five journals were searched using PubMed: Annals of Internal Medicine, British Medical Journal, Journal of American Medical Association, The Lancet, and New England Journal of Medicine. Main outcome is numbers of studies reporting each measure in their abstracts.
    Results: Among abstracts of 334 articles, measures most frequently used were relative risk alone (n = 169), followed by absolute risk alone (n = 92), and raw data alone (n = 58). Reporting of the following measures was relatively limited: both ratio and difference measures (n = 8), raw data with ratio measures (n = 5), and raw data with difference measures (n = 2). None of the studies reported raw data with both ratio and difference measures. Only 15 articles described multiple measures of effect in their abstracts.
    Conclusions: More than half of the RCT abstracts published in the five leading journals in 2016 reported risk ratio alone to indicate effect size. Even abstracts in the five leading journals did not adhere fully to the CONSORT for Abstracts or FDA recommendations.
    Keywords:  absolute risk; abstract; effect measurement; relative risk; submission guidelines
    DOI:  https://doi.org/10.1002/jgf2.306
  30. Transbound Emerg Dis. 2020 Aug 04.
      Animal tuberculosis (TB) caused by Mycobacterium tuberculosis complex (MTC) bacteria remains as one of the most significant infectious diseases of livestock, despite decades of eradication programs and research efforts, in an era where the livestock sector is amongst the most important and rapidly expanding commercial agricultural segments worldwide. This work provides a global overview of the spatial and temporal trends of reported scientific knowledge of TB in livestock, aiming to gain insights into research subtopics within the animal TB epidemiology domain and to highlight territorial inequalities regarding data reporting and research outputs over the years. To deliver such information, peer-reviewed reports of TB studies in livestock were retrieved from the Web of Science and Google Scholar, systematized, and dissected. The validated dataset contained 443 occurrence observations, covering the 1981-2020 period (39 years). We highlight a clear move towards transdisciplinary areas and the One Health approach, with a global temporal increase of publications combining livestock with wildlife and/or human components, which reflect the importance of non-prototypical hosts as key to understanding animal TB. It becomes evident that cattle is the main host across works from all continents, however many regions remain poorly surveyed. TB research in livestock in low-/middle-income countries is markedly growing, reflecting changes in animal husbandry, but also mirroring the globalization era, with a marked increase in international collaboration and capacitation programs for scientific and technological development. This review gives an overview of the most prolific continents, countries, and research fields in animal TB epidemiology, clearly outlining knowledge gaps and key priority topics. The estimated growth trend of livestock production until 2050, particularly in Asia and Africa, in response to human population growth and animal-protein demand, will require further investment in early surveillance and adaptive research to accommodate the higher diversity of livestock species and MTC members and raising the possibility to finetune funding schemes.
    DOI:  https://doi.org/10.1111/tbed.13763
  31. Circ Heart Fail. 2020 Aug 06. CIRCHEARTFAILURE119006605
       BACKGROUND: Gender disparities in authorship of heart failure (HF) guideline citations and clinical trials have not been examined.
    METHODS: We identified authors of publications referenced in Class I Recommendations in United States (n=173) and European (n=100) HF guidelines and of publications of all HF trials with >400 participants (n=118) published between 2001 and 2016. Authors' genders were determined, and changes in authorship patterns over time were evaluated with linear regression and nonparametric testing.
    RESULTS: The median proportion of women authors per publication was 20% (interquartile range [IQR], 8%-33%) in United States guidelines, 14% (IQR, 2%-20%) in European guidelines, and 11% (IQR, 4%-20%) in HF trials. The proportion of women authors increased modestly over time in United States and European guidelines' references (β=0.005 and 0.003, respectively, from 1986 to 2016; P<0.001) but not in HF trials (12.5% [IQR, 0%-20%] in 2001-2004 to 8.9% [IQR, 0%-20%] in 2013-2016; P>0.50). Overall proportions of women as first or last authors in HF trials (16%) did not change significantly over time (P=0.60). North American HF trials had the highest likelihood of having a woman as first or senior author (24%). HF trials with a woman first or senior author were associated with a higher proportion of enrolled female participants (39% versus 26%, P=0.01).
    CONCLUSIONS: In HF practice guidelines and trials, few women are authors of pivotal publications. Higher number of women authors is associated with higher enrollment of women in HF trials. Barriers to authorship and representation of women in HF guidelines and HF trial leadership need to be addressed.
    Keywords:  clinical trial; guideline; heart failure; publications; women
    DOI:  https://doi.org/10.1161/CIRCHEARTFAILURE.119.006605