bims-evares Biomed News
on Evaluation of research
Issue of 2020–06–14
thirty papers selected by
Thomas Krichel, Open Library Society



  1. Contemp Oncol (Pozn). 2020 ;24(1): 17-28
       Aim of the study: To analyze the 100 most cited lung cancer articles published in biomedical literature in the last 44 years. We pointed out developments in lung cancer and aimed to create convenient access for the researchers of this dynamic field.
    Material and methods: We accessed the WoS database (accessed: 15.07.2019) using the keyword "lung cancer" between 1975 and 2019. The top 100 cited articles were analyzed by topic, journal, author, year, institution, level of evidence, adjusted citation index and also the correlations between citation, adjusted citation index, impact factor and length of time since publication.
    Results: A total of 240,701 eligible articles were identified and we chose the top 100 articles cited in the field of lung cancer. The mean number of citations for these articles was 1879.82 ±1264.78. The most cited article was (times cited: 7751) a study by Lynch et al. The New England Journal of Medicine (NEJM) made the greatest contribution to the top 100 list with 32 articles, and the most cited article also originated from NEJM. The highest number of citations was seen in 2017 with 18,393 citations while the highest number of publications was seen in 2005 with 12 publications.
    Conclusions: Oncology is a developing field and we have seen the evolution in this area through the treatment of lung cancer in recent years. The first 100 articles in our analysis not only reflect the landmark articles with the greatest impact on lung cancer research, but also acknowledge the most productive authors and institutions that have contributed to the list with their articles.
    Keywords:  bibliometric study; citation; lung cancer
    DOI:  https://doi.org/10.5114/wo.2020.94725
  2. Ann Med Surg (Lond). 2020 Jul;55 200-206
       Background: The purpose of this study was to better understand the authorship publishing trends in the field of hand surgery. To accomplish this, a comparative analysis was completed between the European and American volumes of the Journal of Hand Surgery (JHSE and JHSA) over the past three decades. Well-established bibliometric methods were used to examine one representative year from each of the past three decades. The focus of the study was to examine changes in author gender over time as well as to compare authorship trends across the two volumes.
    Materials and methods: All JHSA and JHSE publications from 1985, 1995, 2005, and 2015 were placed into a Microsoft Excel spreadsheet. Data was collected for each publication including the gender of first and corresponding authors, corresponding author position, corresponding author country of origin, number of credited institutions, authors, printed pages, and references. Countries were grouped by regions.
    Results: A total of 450 and 763 manuscripts from JHSE and JHSA, respectively, met inclusion criteria. JHSE and JHSA both showed increases in most variables analyzed over time. Both journals showed an increase in female first and corresponding authors. JHSE and JHSA displayed a rise in collaboration between institutions and countries.
    Conclusions: Both JHSE and JHSA display increasing female inclusion in the hand surgery literature, which has traditionally been a male dominated field. The observed increase in collaboration between institutions and countries is likely linked to advances in technology that allow sharing of information more conveniently and reliably than was previously possible. As further advances are made socially and technologically, hopefully these trends will continue, leading to faster and higher quality research being generated in the field of hand surgery.
    Keywords:  Authorship trends; Bibliometric; Comparative analysis; Gender
    DOI:  https://doi.org/10.1016/j.amsu.2020.05.015
  3. Biomed Res Int. 2020 ;2020 2672373
       Objectives: The bibliometric analysis uses the citation count of an article to measure its impact in the scientific community, yet there is still no comprehensive summary of gastric disease researches via bibliometric analysis. We aimed to evaluate the situations and trends of the most cited articles in gastric disease via bibliometric analysis and to provide physicians a practical guide in assessing the most influential articles written on this subject.
    Methods: The 100 top-cited articles in gastric disease were compiled using Web of Science. The articles selected were evaluated for their number of citations, year of publication, country of origin, type of study, and others.
    Results: The database had 484,281 articles published between 1965 and 2019. The most cited article received 4,017 citations and the least received 604, with a mean of 1,149 citations. We classified the articles into seven categories: gastric cancer (n = 53), Helicobacter pylori (n = 17), ulcer (n = 7), gastrointestinal stromal tumors (n = 6), gastritis (n = 5), gastric bypass surgery (n = 2), and others (n = 10). Altogether, 69 of the articles were from the USA (n = 41), the UK (n = 17), and Japan (n = 11). Among all the institutions, Royal Perth Hospital led the list with 5 articles. One-quarter of authors owned three or more of these top-cited articles. The 100 papers were published in 33 journals, and most of them were clinical researches (n = 47).
    Conclusions: Our study provides a historical perspective for the scientific progress of gastric disease, and the articles of significant findings that contributed great impact on the prevention and treatment of gastric disease had been identified.
    DOI:  https://doi.org/10.1155/2020/2672373
  4. J BUON. 2020 Mar-Apr;25(2):25(2): 1178-1192
       PURPOSE: The purpose of this bibliometric study was to point out the emergence and development of immunotherapy in cancer treatment and shifting tendencies on this field in the last years. We aimed to create an ease of access for the researchers of this dynamic field.
    METHODS: Cancer immunotherapy as a search term was queried into Thomson Reuter's Web of Science database of 2019 to list all the articles about this term. The top 100 cited articles were analyzed by topic, journal, author, year, institution, level of evidence, adjusted citation index and also the correlations between citation, adjusted citation index, impact factor and length of time since publication.
    RESULTS: 46,606 eligible articles were found and we had chosen the top 100 cited in the cancer immunotherapy field by bibliometric criteria. The mean citation number for the highly cited articles was 1027794 (range:446-5746). The most cited article on cancer immunotherapy was a phase 1 clinical trial about immune check-point inhibitor (5,271 citations) conducted by Topalian et al. The Science, AAAS journal made the biggest contribution to the top 100 list with 14 articles, whereas the most cited article originated from the New England Journal of Medicine. The country and year with most publications were the USA (n=93) and 2012 (n=10) respectively. National Institutes of Health (n=30) and National Cancer Institute (n=30) were the most prolific institutions.
    CONCLUSION: Cancer immunotherapy is a rapidly developing and changing subspecialty in the realm of oncology. Despite some flaws, this trend topic study has identified the most significant contributions to cancer immunotherapy research over the years and it has revealed many important scientific breakthroughs and landmarks that had took place during this time.
  5. Cien Saude Colet. 2020 Jun;pii: S1413-81232020000602143. [Epub ahead of print]25(6): 2143-2152
      The scope of this study is violence perpetrated against the elderly. It aims to analyze the international scientific production on violence against the elderly. It involved bibliometric research carried out in the ISI Web of Knowledge/Web of ScienceTM database, in which the search terms "elder,"violence" or "abuse" and "health care" were used, in the period between the years 1991 and 2016. The data were analyzed considering the evolution of the annual publications, the journals with the highest number of records, the authors with the highest number of publications, the number of articles distributed by authors' country of origin, and articles with the highest impact. A total of 267 published records in 174 different journals indexed to the database in question were identified and were written by 901 authors with links to 410 institutions located in 39 countries. In the descriptive analysis of the content of the top journals on the topic and of the most cited articles there was potential for the development of the topic, since there is a need for more data on interventions in cases of violence against the elderly, with a multidisciplinary approach, as well as conducting more research on clinical manifestations, quality of life and its economic impact on the use of health services.
    DOI:  https://doi.org/10.1590/1413-81232020256.226322018
  6. Arch Bronconeumol. 2020 Jun 08. pii: S0300-2896(20)30139-3. [Epub ahead of print]
       INTRODUCTION: Gender inequality exists in scientific publications. The aim of this study was to determine changing patterns in gender differences and factors associated with the positioning of authors' names in original articles published in Archivos de Bronconeumología (AB).
    METHODS: We performed a bibliometric study of articles published in AB between 2001 and 2018. Author gender was analysed in four scenarios: first author, last author, middle authors, and mentee authors. Comparisons were made by authors' specialties, funding received, multicentre studies, specialist areas, and others. Multivariate models adjusted for the percentage of registered physicians in the Spanish health system were created to predict the female gender of the first, middle, and last author.
    RESULTS: A total of 828 publications were analysed in which women appeared as first authors in 286 (34.5%) and last authors in 169 (20.4%). A gradual increase in women as first authors was observed (P = .0001), but not as last authors (P = .570). Overall, the average number of female authors increased over time (from 1.6 ± 1.4 in 2001-2005 to 3.3 ± 2.3 in 2016-2018, P = .0001), with no differences in male averages. The adjusted multivariate models reflected a positive bi-directional relationship between the first author and the middle authors, and a negative association between the first author being Spanish and the last author being female (OR 0.57; 95% CI 0.36-0.88, P = .012).
    CONCLUSIONS: Gender differences were found in various aspects of authorship in AB, summarized by a greater participation of women as first and intermediate authors, but not as last authors.
    Keywords:  Análisis bibliométrico; Bibliometric analysis; Gender; Género; Publicaciones; Publications
    DOI:  https://doi.org/10.1016/j.arbres.2020.04.020
  7. Aesthet Surg J. 2020 Jun 07. pii: sjaa158. [Epub ahead of print]
       BACKGROUND: Altmetrics (alternative metrics) has become one of the most commonly used metrics to track the impact of research articles across electronic and social media platforms.
    OBJECTIVE: The goal of this study is to identify whether the Altmetric Attention Score (AAS) is a good proxy for citation counts and whether it can be used as an accurate measure to complement the current gold standard.
    METHODS: We conducted a citation analysis of all articles published in six plastic surgery journals during the 2016 calendar year. Citation counts and AAS were abstracted and analyzed.
    RESULTS: We identified a total of 1,420 articles. The mean AAS was 11 while the median AAS was 1. The journal with the highest mean AAS was Aesthetic Surgery Journal (31), followed by Plastic and Reconstructive Surgery (19). A weak positive correlation was identified (r=0.33, p<0.0001) between AAS and citations. Articles in the top 1% in terms of citation counts showed strong positive correlation between AAS and citation counts (r=0.64, p=0.01). On the contrary, articles in the top 1% of AAS had no significant correlation with citation counts (r=-0.31, p=0.29).
    CONCLUSION: Overall correlation between citations and AAS was weak, and therefor AAS may not be an accurate early predictor of future citations. The two metrics seem to measure different aspects of the impact of scholarly work and should be used in tandem for determining the reach of a scientific article.
    DOI:  https://doi.org/10.1093/asj/sjaa158
  8. Evid Based Complement Alternat Med. 2020 ;2020 5357917
       Objective: To analyze the development of cardio-oncology, summarize the research achievements, and provide proposals for its future research.
    Methods: The web of science database was used to search for "cardio-oncology" and "oncocardiology" related articles from the beginning of the database (1970) to April 5, 2019. Excel 2016 and Cytoscape were used to analyze the trend of cardio-oncology research.
    Results: A total of 356 articles were obtained. The number of articles has grown rapidly in recent years. Cardiac injury caused by tumor therapy was a research hotspot (n = 107). Researchers paid more attention to the prevention and treatment of cardiotoxicity (n = 54). Experimental researches were a small part of all studies (n = 72), mainly focusing on the study of cancer drugs' cardiac injury, test indicators of cardiotoxicity, and preventive drugs. The United States (n = 156.25), Italy (n = 48.5), and Canada (n = 23.5) published the most articles, making a great contribution to the development of cardio-oncology.
    Conclusions: Cardio-oncology has been developing rapidly and receiving a large amount of research efforts in recent years. Most articles on cardio-oncology were published by the authors from the United States (44%) and Italy (17%), while other countries need to pay more attention to cardio-oncology. As an independent discipline, cardio-oncology is certainly in need of significant progress, but it has formed a basic framework, which has obtained many leading theories and meaningful achievements in diagnostic criteria, diagnostic methods, prevention and treatment, mechanism research, and influencing factor. Cardiac injury of tumor drugs has always been a research hotspot in this discipline, and there is still a lot of research space. The research about detection methods of cardiotoxicity and preventive drugs is gradually increasing. Basic research lags behind, and many mechanisms are still unclear.
    DOI:  https://doi.org/10.1155/2020/5357917
  9. Cureus. 2020 May 08. 12(5): e8026
      Objectives The purpose of this analysis was to investigate the quantity and quality of medical students' research output in Gulf Cooperation Council countries to aid in developing strategies to improve research output. Methods Abstracts presented by medical students in Gulf Cooperation Council countries were subject to analysis. Abstracts that propagated into full-length articles underwent further demographic analysis, in which data regarding the type of study, the field of study, country of origin, mode of presentation, and journal's impact factor were collected. A total of 798 abstracts were surveyed, with 19% (n=155) of the abstracts submitted by Gulf Cooperation Council countries progressing into full-length publications. The average impact factor for Gulf Cooperation Council country publications was found to be 1.85 ± 0.26 (standard error). Countries that recorded the highest conversion rates were, in descending order, Kingdom of Saudi Arabia, United Arab Emirates, Oman, Bahrain, and Kuwait. Moreover, basic biomedical and clinical research topics were more likely to be published in comparison with community-oriented and medical education-related topics. Conclusions Effective efforts to encourage more medical student research output in the Gulf Cooperation Council countries (with a focus on qualitative analysis) should be promoted in order to achieve publication rates comparable with those reported by developed countries.
    Keywords:  dissemination; impact factor; publication; quality; quantity; research output
    DOI:  https://doi.org/10.7759/cureus.8026
  10. World Neurosurg. 2020 Jun 06. pii: S1878-8750(20)31221-3. [Epub ahead of print]
       BACKGROUND: Publications are considered as a major factor for advancement in academia. An effort has been made to study authorship trends in Neurosurgery publications.
    OBJECTIVE: To investigate authorship trends in Neurosurgery literature for the last twenty years (1998-2018).
    METHODS: Articles for the year 1998, 2008 and 2018 were extracted from Neurosurgery, Journal of Neurosurgery and World Neurosurgery for this retrospective study. Only original articles, case reports, and review articles were included. The sex of the first, senior, and corresponding author was determined. Subspecialty topic, type of paper, geographical origin of articles, and the number of citations for each article were also collected.
    RESULTS: A total of 3912 articles were included. The number of articles, the total number of authors, and non-experimental studies increased in the successive decades. A total of 744 (19.0%) females were first authors and 520 (13.3%) were female senior authors of their respective publications. A decreasing trend (P=0.00) was noted between female first authors and male senior authors over time. All three journals showed an increasing pattern of female authorships across the two decades.
    CONCLUSION: A rapid rise in female authorship positions in particular and authorship positions, in general, demonstrates the diversity that is slowly burgeoning to cater to perspectives and issues that require a multidimensional approach in Neurosurgery. Increasing linkages amongst researchers in Neurosurgery on a global scale are evident by the increase in multi-national collaborations. Expansive efforts are needed at institutional and individual levels to eradicate gender-based pitfalls that hinder excellence in Neurosurgery research.
    Keywords:  Articles; Authorship; Female; Neurosurgery
    DOI:  https://doi.org/10.1016/j.wneu.2020.05.248
  11. J Clin Orthop Trauma. 2020 May;11(Suppl 3): S354-S361
       Background: Posterior Cruciate Ligament (PCL) is one of the key ligaments of the knee. PubMed data has not been previously analyzed on this topic. This study aims to summarize data of 40 years from 1979 to 2018 in PubMed on this topic.
    Methods: A search was conducted in PubMed on PCL for the last 40 years using a search strategy, and the output was analyzed for further details. Data was also sought from Scopus concerning top universities and countries publishing on PCL as this information was not extractable from PubMed. VOS Viewer was used to analyzing text occurrences in authors and titles visually.
    Results: Total publications on PCL were 5087 from 1915 to 27 February 2019 when this search was done and 5025 in the last 40 years until 31 December 2018. The yearly average of publication numbers has seen a steady increase. Top journal and author on PCL publications were KSSTA and LaPrade RF respectively. Most papers published by a First author was by Fanelli GC. Time-based links of LaPrade RF to other authors were represented as a VOS output. The USA was the most published country, and 8 of 10 Universities which published were from the USA.
    Conclusions: There has been a steady and significant increase in the number of articles published in PubMed since 1979. It is obvious that the topic of PCL has gained attention and importance in the recent past and has seen a steady increase over the last few years. This article summarises the increased interest and could act as a baseline for future studies.
    Level of evidence: Level IV.
    Keywords:  Data mining; Database search; Knee; PCL; Posterior cruciate ligament; PubMed; Publication
    DOI:  https://doi.org/10.1016/j.jcot.2019.10.007
  12. Ther Innov Regul Sci. 2020 Jun 11.
       BACKGROUND: Although a large number of clinical trials have been conducted, the types of clinical trials that are scientifically influential, frequently utilized by society, and contribute to the progress of evidence-based medicine (EBM) have not been studied. Thus, we aimed to investigate the relationship between the characteristics of clinical trials and the scientific impact of the outcome in non-small cell lung cancer (NSCLC) by performing a bibliometric analysis using relative citation ratio (RCR), a newly developed bibliometric index by the National Institutes of Health (NIH).
    METHODS: Primary publications of drug intervention clinical trials for NSCLC between 2007 and 2016 were included in the study. The characteristics of clinical trials were compared among four RCR categories with 50 trials in each [LOW50, 50 NIH percentile (50NIH%ile), 95 NIH percentile (95NIH%ile), and TOP50], totaling to 200 trials.
    RESULTS: Median RCRs of LOW50, 50NIH%ile, 95NIH%ile, and TOP50 were 0.03, 1.00, 5.76, and 26.89, respectively. Publications of Phase 3, randomized, blinded, for-profit-company supported/sponsored, multi-center trials, and trials with a larger number of subjects were shown to have a higher scientific impact. Publications of clinical trials of newly developed molecular target drugs, including epidermal growth factor receptor-tyrosine kinase inhibitors, anaplastic lymphoma kinase inhibitors, and immune checkpoint inhibitors demonstrated a higher scientific impact than those of traditional chemotherapies.
    CONCLUSION: Clinical trials designed to have a high evidence level would improve the scientific impact of the outcome, and novel interventions would be another factor to improve the clinical trials' influence.
    Keywords:  Bibliometric analysis; Clinical trial design; Evidence-based medicine; Non-small cell lung cancer; Relative citation ratio
    DOI:  https://doi.org/10.1007/s43441-020-00177-5
  13. Endocr Metab Immune Disord Drug Targets. 2020 Jun 07.
       AIM: To add to previous analyses and describe the trends in MSA research from three decades, 1988 to 2018, through assessing the medical literature. Additionally, a collaboration network was analyzed to determine the most common process in development of MSA research.
    METHODS: This research was a descriptive survey with a scientometric approach. The data for the present study were collected from the Web of Science (WoS) and search strategy based on Medical Subject Heading (MeSH) term. In this research, the data analysis was performed based on collaboration network and theme analysis.
    RESULTS AND CONCLUSION: In this study, 6530 articles were retrieved from 1988 to 2018 in three different periods. These articles were drafted by 39,184 authors, 3,865 organizations, 80 countries, and 832 journals. Further, 287 articles with more than 100 citations were found. The global citation score (GCS) was 250,834 times and the average cited times per articles was reported as 3,841. The MSA research field demonstrated a diagram for a chronological period to assess the most relevant themes. Each diagram depended on the sum of documents linked to each research topic. Scientometric analysis of the field of MSA can be regarded as a roadmap for future research and policymaking in this important area.
    Keywords:  Multiple System Atrophy; articles.; research; scientometric; theme; trend
    DOI:  https://doi.org/10.2174/1871530320666200607194810
  14. Ann Med Surg (Lond). 2020 Jul;55 195-199
       Background: The posterior cruciate ligament (PCL) is one of the rare operated ligament of the knee. Details on the top journals, universities, and authors on the topic would be helpful to identify the sources of information for clinical and research queries as well as to observe trends for future research and identify universities/authors of particular interest for training or to follow their research.
    Purpose: To consolidate information from PubMed on the PCL from 2009 to 2019, spanning 10 years.
    Study design: Cross-sectional study.
    Methods: A search of the PubMed database was conducted for the PCL, and 593 articles published over the past 10 years were analysed for further details. These details included the number of publications per year, top 10 journals publishing on the PCL, top 10 first authors publishing articles on the PCL.
    Results: The top journal and top author in all position publishing on the PCL were Knee surgery, sports traumatology, arthroscopy and Robert F. LaPrade, respectively. The most articles published by a first author were by Yong Seuk Lee. The United States was the most published country, and 4 of the top 10 affiliations were from this country.
    Conclusion: Mining the data on the PCL in PubMed produced useful information about good sources of publications on this topic, including authors/journals that could be followed. The strength of their association with other authors could potentially indicate co-workers, common research interests, and collaborative studies.
    Keywords:  Database search; Knee; PCL; Posterior cruciate ligament; PubMed; Publication
    DOI:  https://doi.org/10.1016/j.amsu.2020.05.040
  15. Am J Psychother. 2020 Jun 08. appipsychotherapy20190045
       OBJECTIVE: Bibliometric analyses are commonly used to document publication trends over time; however, this methodology has not been used to investigate possible trends concerning publishing about psychotherapy brands. In this study, the authors sought to identify the publication trends of peer-reviewed articles about 30 psychotherapy brands.
    METHODS: Analyses were focused on the past 50 years and on each decade from 1970 to 2019. All searches were performed between October 2018 and January 2019 on the EbscoHost platform. Two databases were selected for the searches: PsycINFO and PubMed.
    RESULTS: In the 28,594 articles reviewed, most published articles concerned cognitive-behavioral therapy (CBT), and five brands accounted for almost 78% of all publications: CBT, psychoanalysis, family systems therapy, behavioral therapy, and cognitive therapy. Three trends were identified across decades: five therapies consistently yielded the largest number of publications, the number of publications focused on therapies with less research support declined from the 1970s to the 1990s, and publications about therapies with more of a research basis increased in the 1990s through the 2010s. Publications on meditation and mindfulness presented the most salient growth area for all psychotherapies across the 5 decades. A few psychotherapy brands have dominated the publishing realm during the past 50 years and across each decade.
    CONCLUSIONS: Possible explanations for these publication trends were considered, including the emergence of the evidence-based therapy movement and various sociohistorical changes. Potential psychotherapy publications trends in the future are discussed.
    Keywords:  bibliometric; brands; psychotherapy; publication; trends
    DOI:  https://doi.org/10.1176/appi.psychotherapy.20190045
  16. Orthop J Sports Med. 2020 May;8(5): 2325967120920782
       Background: Orthopaedic sports medicine fellowship positions are increasing in popularity, as evidenced by the increasing number of applicants to these programs. As positions have become more competitive, greater emphasis has been placed on an applicant's research experience. However, there has been a lack of research evaluating the accuracy of self-reported publications from fellowship applications.
    Purpose: To evaluate the accuracy of self-reported research publications and the outcomes of studies submitted for publication by applicants to an Accreditation Council for Graduate Medical Education (ACGME)-accredited sports medicine fellowship in the United States (US).
    Study Design: Cross-sectional study.
    Methods: Demographic and research publication data were retrospectively collected from 435 applications to an ACGME-accredited orthopaedic sports medicine fellowship program at a single high-volume academic institution from 2013 to 2017. All self-reported manuscript publications and studies in progress were analyzed with a minimum 2-year follow-up. "Submitted" publications were reviewed by searching the originally submitted journal and all publicly available sources. Publications were verified on PubMed, MEDLINE, and other open access journals. Journal impact factors were collected through use of InCites Journal Citation Reports.
    Results: Only 5.7% (85/1504) of papers reported as "completed" were inaccurately self-reported, with 44 (51.8%) remaining unverified and 41 (48.2%) reporting discordant authorship, in which the published study listed a different author order than reported on the application. Further, 28.3% (197/696) of papers self-reported as "submitted" remained unpublished, 21.8% (152/696) were published in a different journal than originally reported, and 7.6% (53/696) were published with a different authorship order than reported. Among 95 applicants whose papers were published in different journals than originally reported, the mean impact factor of the final accepting journal was significantly lower than that of the journal of original submission (0.97 ± 0.13 vs 3.91 ± 0.79, respectively; 95% CI of the difference, 1.34-4.54; P < .01). Univariate analysis showed no significant relationships between variables of interest (age, sex, US Medical Licensing Examination Step 1 score, American Orthopaedic Association membership, medical school ranking, and advanced degree) and the presence of an inaccuracy.
    Conclusion: There is a low rate of inaccurate self-reporting of "completed" publications on applications for orthopaedic sports medicine fellowships. The majority of papers listed as "submitted" on these applications were not published in the journals to which they were originally submitted.
    Keywords:  applications; education; orthopaedic surgery; research authorship; sports medicine fellowship
    DOI:  https://doi.org/10.1177/2325967120920782
  17. Bull Hosp Jt Dis (2013). 2020 Jun;78(2): 115-122
       BACKGROUND: This study reviews and identifies various trends and characteristics of spine research published by The Journal of Bone & Joint Surgery (JBJS) from 2008 through 2017.
    METHODS: A PubMed search of all studies published in JBJS from 2008 to 2017 was performed using the keyword "spine." A similar search was conducted on the JBJS website. Citations, authorship, academic degrees, country of origin, topic, level of evidence, positive or negative outcome, and patient-reported outcomes were analyzed.
    RESULTS: A total of 163 articles were selected using exclusion criteria. The most cited article was referenced 513 times per Google Scholar and 318 times per Web of Science. The most popular research topics were related to either the cervical spine (approximately 22% of articles) or scoliosis (approximately 22% of articles). The United States was responsible for 73.0% of the articles in the study, followed by China at 6.1%. Fifty-eight articles used at least one patient-reported outcome measurement (PROM), most commonly the Short Form Questionnaire.
    CONCLUSIONS: A strong emphasis on international publications and an increase in authorship are evident. Level of evidence (LOE) I or II studies received 2.4 times as many citations on average as LOE III or IV studies. While no evidence of a positive publication bias from JBJS was found, there appears to be a lack of standardization of patient reported outcome measurements in spine research. Finally, spine articles discussing medical protocols or patient management garnered an average of 1.6 times as many citations as spine studies that explored other topics.
  18. Adv Radiat Oncol. 2020 May-Jun;5(3):5(3): 325-332
       Purpose: We examined whether female authorship, traditionally underrepresented in the radiation oncology (RO) literature, has improved during the past decade, and whether the introduction of double-blind peer review (where reviewers are blinded to author names and vice-versa) improved female authorship rates.
    Methods: We analyzed authorship lists during a 10-year period (2007-2016) from the 2 highest impact-factor RO journals: The International Journal of Radiation Oncology, Biology, Physics (IJROBP) and Radiotherapy and Oncology (R&O). From each journal, 20 articles per year were randomly selected. Gender trends of the first, second, last, and collaborating authors (defined as all other positions), were analyzed. A one-sample proportion test was used to compare US female senior authorship (2012-2016) with the 2015 benchmark for female US academic radiation oncologists (30.6%).
    Results: Across 400 articles, the mean ± standard deviation percentage of female authors was 30.9% ± 22.0% with 34.8% of first, 36.7% of second, and 25.4% of last authors being female. The total percentage of female authors per year increased from 2007 to 2016 (P = .005), with no significant increase in the percentage of first (P = .250), second (P = .063), or last (P = .213) female authors. Double-blind peer review was associated with an increase in the mean percentage of female authors (2007-2011: 27.4% vs 2012-2016: 34.0%; P = .012). The proportion of US female senior authors in the latter period (27.6%) and the proportion of female US academic radiation oncologists (30.6%) were not significantly different (P = .570).
    Conclusions: Although the percentage of female authors in RO has increased during the past decade, this did not correspond to a higher representation of women in high-profile authorship positions. Introduction of double-blind peer review was associated with a rise in female authorship. The proportion of female US senior authors and academic radiation oncologists is similar, suggesting that senior authorship rates are approaching appropriate levels in the United States.
    DOI:  https://doi.org/10.1016/j.adro.2019.09.002
  19. Animals (Basel). 2020 Jun 06. pii: E993. [Epub ahead of print]10(6):
      Trap-Neuter-Return and its variants (hereafter TNR) aims to control unowned cat populations. Papers on this topic form a useful case study of how how an area of literature grows, papers become influential, and citation networks form, influencing future study as well as public perceptions of the science. We analysed 145 TNR studies published 2002-2019. Common topics, identified by frequently used language, were population control, interactions with wildlife, disease transmission (including implications for pets, wildlife and humans), free-roaming cats, and feral and domestic cat management. One or more papers on each of these topics was judged influential because of high citations overall, high average citations/year, or frequent mentions in social media. Open Access papers were more influential in social media, raising greater public awareness than studies published in journals that were less accessible. While divergent views exist on a range of topics, the network analysis of the TNR literature indicated potential for forming self-reinforcing groups of authors. While it is encouraging that diverse views are expressed, there is a risk of reduced dialogue interactions between groups, potentially constraining dialogue to refine arguments, share information, or plan research. Journal editors could encourage communication by choosing reviewers from different camps to assess manuscripts and by asking authors to acknowledge alternative views.
    Keywords:  TNR; citation bias; citation network
    DOI:  https://doi.org/10.3390/ani10060993
  20. Proc Natl Acad Sci U S A. 2020 Jun 08. pii: 202001064. [Epub ahead of print]
      The growing popularity of bibliometric indexes (whose most famous example is the h index by J. E. Hirsch [J. E. Hirsch, Proc. Natl. Acad. Sci. U.S.A. 102, 16569-16572 (2005)]) is opposed by those claiming that one's scientific impact cannot be reduced to a single number. Some even believe that our complex reality fails to submit to any quantitative description. We argue that neither of the two controversial extremes is true. By assuming that some citations are distributed according to the rich get richer rule (success breeds success, preferential attachment) while some others are assigned totally at random (all in all, a paper needs a bibliography), we have crafted a model that accurately summarizes citation records with merely three easily interpretable parameters: productivity, total impact, and how lucky an author has been so far.
    Keywords:  bibliometric indexes; rich get richer; science of science; scientometrics
    DOI:  https://doi.org/10.1073/pnas.2001064117
  21. Cytometry A. 2020 Jun 08.
      Briefly depicted are the publications in CYTOMETRY that received the highest frequency of citations. Among them are seminal papers describing application of metachromatic fluorochrome acridine orange to differentially stain DNA versus RNA or to analyze susceptibility of DNA in situ to denaturation; both features being markers of different sections of the cell cycle including identification of noncycling quiescent cells. The papers reviewing detection of cyclins D1, E, A or B1, each in relation to cell cycle phase, were also among the highly cited ones. The highest citation rates received publications describing development of the TUNEL methodology to detect apoptotic DNA fragmentation, and more recently expression of ϒH2AX to reveal DNA damage. © 2020 International Society for Advancement of Cytometry.
    Keywords:  FLICA methodology; TUNEL methodology; acridine orange; cell cycle; cell death; chromatin structure; cyclin proteins; histone H3 phosphorylation; laser scanning cytometry; ϒH2AX
    DOI:  https://doi.org/10.1002/cyto.a.24043
  22. Neurourol Urodyn. 2020 Jun 07.
       AIMS: Evaluation and treatment of functional conditions of the lower urinary tract (fcLUT), a subset of benign urinary tract conditions, is highly subjective due to overlapping symptomatology. Despite high prevalence and socioeconomic cost, there has been little improvement in their treatment and lack of progress in understanding their pathophysiology. This study investigates trends in quantity, monetary amounts, and awardees' characteristics of federally funded research awards for fcLUT compared to nonurologic benign conditions (NUBCs) and urologic malignancies.
    METHODS: Data were extracted from the National Institutes of Health (NIH) and federal RePORTER databases in December 2019. We identified currently active awards in fcLUT, NUBC, and malignant urologic conditions and the associated demographic features of awardees. The authors also examined temporal funding trends for such awards.
    RESULTS: These database searches revealed that there are consistently fewer awards and funding dollars for the study of fcLUT compared to other benign conditions with similar prevalences. While most research topics have received increased funding in awards and overall funding dollars over time, fcLUT funding has remained relatively flat. Urologists are also underrepresented; only 11 of the 86 recipients of NIH R01 awards to study fcLUT have clinical training in urology.
    CONCLUSIONS: Even when compared to NUBC, funding for the study of fcLUT remains low and has stagnated over time. Further, investigators who are clinicians in the field of urology are in the minority of those doing this study. Given the need for clinical perspectives in fcLUT research, the lack of urologist representation will inhibit discovery and translational advances.
    Keywords:  National Institutes of Health; benign urology; female pelvic medicine and reconstructive surgery; incontinence; research funding; voiding dysfunction
    DOI:  https://doi.org/10.1002/nau.24413
  23. Front Psychol. 2020 ;11 917
      Driving behaviors and fitness to drive have been assessed over time using different tools: standardized neuropsychological, on-road and driving simulation testing. Nowadays, the great variability of topics related to driving simulation has elicited a high number of reviews. The present work aims to perform a scientometric analysis on driving simulation reviews and to propose a selective review of reviews focusing on relevant aspects related to validity and fidelity. A scientometric analysis of driving simulation reviews published from 1988 to 2019 was conducted. Bibliographic data from 298 reviews were extracted from Scopus and WoS. Performance analysis was conducted to investigate most prolific Countries, Journals, Institutes and Authors. A cluster analysis on authors' keywords was performed to identify relevant associations between different research topics. Based on the reviews extracted from cluster analysis, a selective review of reviews was conducted to answer questions regarding validity, fidelity and critical issues. United States and Germany are the first two Countries for number of driving simulation reviews. United States is the leading Country with 5 Institutes in the top-ten. Top Authors wrote from 3 to 7 reviews each and belong to Institutes located in North America and Europe. Cluster analysis identified three clusters and eight keywords. The selective review of reviews showed a substantial agreement for supporting validity of driving simulation with respect to neuropsychological and on-road testing, while for fidelity with respect to real-world driving experience a blurred representation emerged. The most relevant critical issues were the a) lack of a common set of standards, b) phenomenon of simulation sickness, c) need for psychometric properties, lack of studies investigating d) predictive validity with respect to collision rates and e) ecological validity. Driving simulation represents a cross-cutting topic in scientific literature on driving, and there are several evidences for considering it as a valid alternative to neuropsychological and on-road testing. Further research efforts could be aimed at establishing a consensus statement for protocols assessing fitness to drive, in order to (a) use standardized systems, (b) compare systematically driving simulators with regard to their validity and fidelity, and (c) employ shared criteria for conducting studies in a given sub-topic.
    Keywords:  driving simulation; driving simulator; fitness to drive; review; scientometric analysis
    DOI:  https://doi.org/10.3389/fpsyg.2020.00917
  24. Int J Environ Res Public Health. 2020 Jun 08. pii: E4095. [Epub ahead of print]17(11):
      Novel coronavirus disease 19 (COVID-19) is a global threat to millions of lives. Enormous efforts in knowledge production have been made in the last few months, requiring a comprehensive analysis to examine the research gaps and to help guide an agenda for further studies. This study aims to explore the current research foci and their country variations regarding levels of income and COVID-19 transmission features. This textual analysis of 5780 publications extracted from the Web of Science, Medline, and Scopus databases was performed to explore the current research foci and propose further research agenda. The Latent Dirichlet allocation was used for topic modeling. Regression analysis was conducted to examine country variations in the research foci. Results indicate that publications are mainly contributed by the United States, China, and European countries. Guidelines for emergency care and surgical, viral pathogenesis, and global responses in the COVID-19 pandemic are the most common topics. There is variation in the research approaches to mitigate COVID-19 problems in countries with different income and transmission levels. Findings highlighted the need for global research collaborations among high- and low/middle-income countries in the different stages of pandemic prevention and control.
    Keywords:  COVID-19; content analysis; scientometrics; text mining
    DOI:  https://doi.org/10.3390/ijerph17114095
  25. Glob Health Action. 2020 Dec 31. 13(1): 1768795
      In 2008 nine African Universities and four African research institutions, in partnership with non-African institutions started the Consortium for Advanced Research Training in Africa (CARTA) to strengthen doctoral training and research capacity on health in Africa. This study describes particular aspects of the CARTA program that promotes collaboration between the PhD fellows in the program, and determines the patterns of collaborative publications that resulted from the intervention. We reviewed program monitoring and evaluation documents and conducted a bibliometric analysis of 806 peer-reviewed publications by CARTA fellows published between 2011 and 2018. Results indicate that recruiting multidisciplinary fellows from various institutions, encouraging registration of doctoral-level fellows outside home institutions, and organizing joint research seminars stimulated collaborative research on health-related topics. Fellows collaborated among themselves and with non-CARTA researchers. Fellows co-authored 75 papers (10%) between themselves, of which 53 (71%) and 42 (56%) included fellows of different cohorts and different disciplines respectively, and 19 (25%) involved fellows of different institutions. CARTA graduates continued to publish with each other after graduating - 11% of the collaborative publications occurred post-graduation - indicating that the collaborative approach was maintained after exiting from the program. However, not all fellows contributed to publishing collaborative papers. The study recommends concerted effort towards enhancing collaborative publications among the CARTA fellows, both doctoral and post-doctoral, which can include holding research exchange forums and collaborative grant-writing workshops.
    Keywords:  Africa; Collaborative publications; doctoral intervention; networks; post-doctoral intervention
    DOI:  https://doi.org/10.1080/16549716.2020.1768795
  26. Vis Comput Ind Biomed Art. 2020 Jun 08. 3(1): 14
      In the construction area, visuals such as drawings, photos, videos, and 3D models, play a significant role in the design, build and maintenance of a facility, bringing efficiency to generate, transfer, and store information. Advanced visual computing techniques facilitate the understanding of design contents, work plans, and other types of information shared in the construction industry. Automatic visual data collection and analysis provide many possibilities to the construction industry and a large number of works have investigated how visual computing can improve construction management processes and other problems in the construction area. However, a comprehensive literature review is needed. This study uses bibliometric approaches to review the works published to date, and analyses the development of knowledge, significant research results, and trends. The purpose of this study is to help newcomers to this research field understand knowledge structure and formulate research directions, thereby enhancing knowledge development. From this study, it can be concluded that computer vision is a key axis of improvement. Moreover, building information modeling, laser scanning, and other visualization-related techniques are also important in advancing the construction area.
    Keywords:  Augmented reality; Bibliometric analysis; Building information modeling; Construction application; Construction management; Laser scanning; Visual computing
    DOI:  https://doi.org/10.1186/s42492-020-00050-0
  27. Ann Thorac Surg. 2020 Jun 03. pii: S0003-4975(20)30860-2. [Epub ahead of print]
       BACKGROUND: The Thoracic Surgery Social Media Network (TSSMN) is a collaborative effort of leading journals in cardiothoracic surgery to highlight publications via social media. This study aims to evaluate the 1-year results of a prospective randomized social media trial to determine the effect of tweeting on subsequent citations and non-traditional bibliometrics.
    METHODS: A total of 112 representative original articles were randomized 1:1 to be tweeted via TSSMN or a control (non-tweeted) group. Measured endpoints included citations at 1-year compared to baseline, as well as article-level metrics (Altmetric score) and Twitter analytics. Independent predictors of citations were identified through univariable and multivariable regression analyses.
    RESULTS: When compared to control articles, tweeted articles achieved significantly greater increase in Altmetric scores (Tweeted 9.4±5.8 vs. Non-Tweeted 1.0±1.8, p<0.001), Altmetric score percentiles relative to articles of similar age from each respective journal (Tweeted 76.0±9.1%ile vs. Non-Tweeted 13.8±22.7%ile, p<0.001), with greater change in citations at 1 year (Tweeted +3.1±2.4 vs. Non-Tweeted +0.7±1.3, p<0.001). Multivariable analysis showed that independent predictors of citations were randomization to tweeting (OR 9.50; 95%CI 3.30-27.35, p<0.001), Altmetric score (OR 1.32; 95%CI 1.15-1.50, p<0.001), open-access status (OR 1.56; 95%CI 1.21-1.78, p<0.001), and exposure to a larger number of Twitter followers as quantified by impressions (OR 1.30, 95%CI 1.10-1.49, p<0.001).
    CONCLUSIONS: One-year follow-up of this TSSMN prospective randomized trial importantly demonstrates that tweeting results in significantly more article citations over time, highlighting the durable scholarly impact of social media activity.
    DOI:  https://doi.org/10.1016/j.athoracsur.2020.04.065
  28. J Urol. 2020 May 12. 101097JU0000000000001136
      
    Keywords:  Citation; Social Media; Twitter; Urology; Visual Abstract
    DOI:  https://doi.org/10.1097/JU.0000000000001136
  29. Cien Saude Colet. 2020 Jun;pii: S1413-81232020000602377. [Epub ahead of print]25(6): 2377-2386
      The aim of this paper is to describe the main systems of hierarchization in the Mexican medical field (and those of other similar Latin American countries). Drawing on Bourdieu's genetic structuralism, our hypothesis is that the structure of the medical field is closely correlated with the schemes of perception and appreciation of the medical field's agents. These schemes are rooted in hierarchical classifications by which work is organized and the main agents' prestige is allocated. Empirical data include focus groups, interviews and observations in hospitals, as well as images, memes and other graphic displays found in Facebook and other public internet locations. The analysis sought to identify the main systems of hierarchization that structure both the academic training and the professional practice of physicians. Four systems of hierarchization are identified: professional, by subfields, by specialties, and by division of labor. These systems of hierarchization, reciprocally entangled with one another, are part of the complex structure of positions within the medical field, as well of the agents' schemes of perception and appreciation which are embodied under the form of habitus.
    DOI:  https://doi.org/10.1590/1413-81232020256.28142019
  30. Cancers (Basel). 2020 Jun 05. pii: E1480. [Epub ahead of print]12(6):
      Cripto is a small glycosylphosphatidylinisitol (GPI)-anchored and secreted oncofetal protein that plays important roles in regulating normal physiological processes, including stem cell differentiation, embryonal development, and tissue growth and remodeling, as well as pathological processes such as tumor initiation and progression. Cripto functions as a co-receptor for TGF-β ligands such as Nodal, GDF1, and GDF3. Soluble and secreted forms of Cripto also exhibit growth factor-like activity and activate SRC/MAPK/PI3K/AKT pathways. Glucose-Regulated Protein 78 kDa (GRP78) binds Cripto at the cell surface and has been shown to be required for Cripto signaling via both TGF-β and SRC/MAPK/PI3K/AKT pathways. To provide a comprehensive overview of the scientific literature related to Cripto, we performed, for the first time, a bibliometric analysis of the biological roles of Cripto as reported in the scientific literature covering the last 10 years. We present different fields of knowledge in comprehensive areas of research on Cripto, ranging from basic to translational research, using a keyword-driven approach. Our ultimate aim is to aid the scientific community in conducting targeted research by identifying areas where research has been conducted so far and, perhaps more importantly, where critical knowledge is still missing.
    Keywords:  CRIPTO; TDGF-1; bibliometric analysis; biochemistry and molecular biology; cancer; development; experimental medical research
    DOI:  https://doi.org/10.3390/cancers12061480