bims-evares Biomed News
on Evaluation of research
Issue of 2019–01–20
fourteen papers selected by
Thomas Krichel, Open Library Society



  1. Arch Cardiovasc Dis. 2019 Jan 10. pii: S1875-2136(18)30194-3. [Epub ahead of print]
       BACKGROUND: Cardiovascular disease (CVD) is a major cause of death worldwide, and fruitful research is needed for future advances in this field.
    AIMS: To analyse the scientific production and vitality of French cardiovascular clinical research, and its evolution over the last decade.
    METHODS: We first used Lab Times online data obtained through the Web of Science (Thomson-Reuters, Toronto, ON, Canada), then the PubMed database (National Center for Biotechnology Information [NCBI], Bethesda, MD, USA), for studies published between 2005 and 2015 in the multidisciplinary and cardiology journals with the highest impact factors. French abstracts submitted and accepted at the European Society of Cardiology (ESC) congress were provided directly by the ESC. The number of cardiovascular projects was analysed through the http://www.ClinicalTrials.gov database and the French site for government-funded projects, over the decade from 2008 to 2017.
    RESULTS: Overall, France was ranked fifth in Europe and eighth worldwide for CVD publications. During the 10-year period from 2005 to 2015, French publications accounted for 0.2-0.3% of articles in top multidisciplinary journals and 2% of articles in top cardiology journals. We observed a steady decrease in French abstract submissions at the ESC congress (from 5% to 3.5% in 10 years), and in 2017, France was ranked eighth in Europe. Across European countries, France has been ranked first for declared cardiovascular research on http://www.ClinicalTrials.gov over the last 3 years, for both interventional and observational studies. Regarding the Hospital Programme of Clinical Research, heart ranked second after neurosciences.
    CONCLUSIONS: France is very well represented in terms of new CVD projects, but actual French scientific production scores poorly. Investing in CVD research is a priority to increase the level of publication and to compete with other leading countries.
    Keywords:  Bibliometry; Bibliométrie; Cardiovascular research; Publications; Recherche cardiovasculaire
    DOI:  https://doi.org/10.1016/j.acvd.2018.11.003
  2. J Neurointerv Surg. 2019 Jan 17. pii: neurintsurg-2018-014600. [Epub ahead of print]
       BACKGROUND AND PURPOSE: Endovascular thrombectomy (EVT) has revolutionized the management of acute ischemic stroke. Landmark clinical trials have shown EVT to be one of the most efficacious interventions in clinical medicine over the past 5 years. A method of recognition for an article in the scientific community is to use a citation rank list, in order to identify the seminal works in the academic medical literature. The objective of this study was to characterize the 100 most highly cited articles assessing endovascular management of acute ischemic stroke.
    METHODS: We conducted a retrospective bibliometric analysis using the Web of Science Citation Index Expanded database for the most cited works in the endovascular management of acute ischemic stroke. Citation count was used to rank the top 100 articles, which were then analyzed for authorship, year of publication, subject, study type, level of evidence, and subject.
    RESULTS: The mean number of citations was 245 (range 65-1726) and 394 on Google Scholar. The top 100 articles were cited an average of 43.9 times per year and published in 21 journals in the past two decades. The majority of papers (62) were classified as constituting levels 1, 2, or 3 evidence, and included 17 randomized controlled trials. Approximately two-thirds of the top 100 articles originated from the USA.
    CONCLUSIONS: This study details the most cited articles in the endovascular management of acute ischemic stroke, and furthermore shows that a high proportion of level I evidence exists for this intervention.
    Keywords:  intervention; thrombectomy
    DOI:  https://doi.org/10.1136/neurintsurg-2018-014600
  3. Turk Neurosurg. 2018 Sep 11.
       AIM: Significant growth has been observed in the utilization of spinal fusion in recent years. However, bibliometric studies detailing the quantity and citation number of articles in spinal fusion are lacking. This study is aimed at conducting a scientometric assessment of the research activities of spinal fusion in various subspecialties carried out by different surgeons Material and Methods: All articles regarding spinal fusion research on Web of Science from the year 1994 to 2015 were identified and analyzed in the following aspects: year of publication, publication journal, number of times cited, Hirsch index (H-index), spine surgeon specialty, and country/territory.
    RESULTS: A total of 15060 articles were identified. The average research productivity was 109.09±23.26 articles for cervical spine, 90.09±52.56 articles for thoracic spine, and 304.91±181.63 articles for lumbar. The productivity by neurosurgeons was 9474 articles published, while the orthopedic surgeons published 8263 articles. The average number of citations were 19.61 times for neurosurgeons, and 20.36 times for orthopedic surgeons. In most countries neurosurgoens published more articles than orthopedic surgeons or at least the same amount, but orthopedic surgeons in China and Germany published far more articles than neurosurgeons. The United States published the greatest number of articles, and had the highest total citations and H-index.
    CONCLUSION: Neurosurgeons tend to publish more articles regarding spinal fusion, but orthopedic surgeons seem to have higher citations. North America, West Europe and East Asia were the most productive regions in spinal fusion research, and the United States made the most academic contributions to this area.
    DOI:  https://doi.org/10.5137/1019-5149.JTN.23172-18.2
  4. Ann Pharm Fr. 2019 Jan;pii: S0003-4509(18)30111-1. [Epub ahead of print]77(1): 1-14
      There are several indicators to evaluate the impact of the scientific publication in pharmacy. Given their number, complexity, heterogeneity, strengths and weaknesses, we believe that pharmacists are not sufficiently familiar with these indicators. The main objective is to present an inventory of available indicator to measure the research impact. PubMed, GoogleScholar and Google were interviewed in October 2017 from the following terms: bibliométrique/bibliometrics, facteur d'impact/impact factor, impact de citations/citation impact, revue/journal, chercheur/researcher, article, indicateur/indicator, score. For each identified indicator, the following variables were extracted: name, calculation method, calculation time window, data sources considered, access conditions, inclusion of self-citation, strengths and weaknesses. A total of 15 indicators were included: seven for journals, four for researchers and four for articles. Among them two are non-bibliometric indicators: the Altmetric attention score, the RGscore and one other indicator deriving from the impact factor: the SIGAPS indicator developed to finance the research activity of French hospitals. Of the 12 bibliometric indicators, nine include self-citation. All involve forces (e.g. exclusion of editorials, letters, free access) and weaknesses (e.g. self-citations included, time window too short, disciplinary indistinction). There is no indicator with no weaknesses and pharmacists should be able to understand their strengths and weaknesses.
    Keywords:  Bibliometric; Bibliométrie; Citation; Impact; Indicateur; Indicator; Pharmacie; Pharmacy; Publication scientifique; Scientific publication
    DOI:  https://doi.org/10.1016/j.pharma.2018.09.001
  5. J Plast Surg Hand Surg. 2019 Jan 18. 1-4
      Academic output is just one aspect of a successful career as a plastic surgeon. However, for those with a strong interest in academia, the academic output of a department will likely be a key factor when deciding how to rank jobs. The aim of this study was to quantify and rank the academic output of plastic surgery units across the UK and Ireland. The Institute for Scientific Information (ISI) Web of Science Bibliometric analysis tool was used to collate cumulative (1950-2016), 10 year (2006-2016) and 3 years (2013-2015) research output data for plastic surgery units in the UK and Ireland. Sixty-six plastic surgery units were identified. Departments were ranked for each time period according to the number of papers produced, number of citations (Nc) and h-index (a measure of the impact of scientific output). The top 3 departments for number of papers in the last 10 years were The Royal Free Hospital, London (226) Broomfield Hospital, Chelmsford (218), and Morriston Hospital and Swansea (188). The top 3 for h-number were The Royal Free Hospital (21) Wythenshawe Hospital, Manchester (18) and Morriston Hospital (17). Academic output varies across plastic surgery units in the UK and Ireland. A number of departments have consistently maintained high academic outputs across the years and will be of interest to surgeons hoping to pursue a career in academia.
    Keywords:  Academic output; Hirsh index; bibliometric analysis; plastic surgery
    DOI:  https://doi.org/10.1080/2000656X.2018.1556669
  6. Acad Emerg Med. 2019 Jan 13.
       BACKGROUND: The purpose of this study was to complete a comprehensive analysis of gender differences in faculty rank among United States (U.S.) emergency physicians that reflected all academic emergency physicians.
    METHODS: We assembled a comprehensive list of academic emergency medicine physicians with U.S. medical school faculty appointments from Doximity. com linked to detailed information on physician gender, age, years since residency completion, scientific authorship, National Institutes of Health (NIH) research funding, and participation in clinical trials. To estimate gender differences in faculty rank, multivariable logistic regression models were used that adjusted for these factors.
    RESULTS: Our study included 3600 academic physicians (28%, or 1016, female). Female emergency physicians were younger than their male colleagues [mean age, years (+SD), was 43.8 (+ 8.7) for females and 47.4 (+ 9.9) for males (p<0.001)], had fewer years since residency completion (12.4 vs. 15.6 years, p<0.001), had fewer total and first/last author publications [4.7 vs. 8.6 total publications, p<0.001; 4.3 vs. 7.1 first or last author publications, p<0.001], and were less likely to be principal investigators on NIH grants [1.2% vs. 2.9%, p=0.002] or clinical trials [1.8% vs. 4.4%, p<0.001]. In unadjusted analysis, male physicians were more likely than female physicians to hold the rank of Associate or Full Professor vs. Assistant Professor [13.7 percentage point difference, p<0.001], a relationship that persisted after multivariable adjustment [5.5 percentage point difference, p=0.001].
    CONCLUSIONS: Female academic emergency medicine physicians are less likely to hold the rank of Associate or Full Professor compared to male physicians even after detailed adjustment for other factors that may influence faculty rank. This article is protected by copyright. All rights reserved.
    DOI:  https://doi.org/10.1111/acem.13685
  7. J Foot Ankle Surg. 2019 Jan 15. pii: S1067-2516(18)30393-4. [Epub ahead of print]
      The aim of this study was to demonstrate the state of diabetic foot ulcer (DFU) research in the past 10 years by bibliometric analysis, especially by performing document co-citation and co-word visualization analysis to reveal the research hotspots, frontiers, and core literature. The literature in connection with DFUs from 2007 to 2018 was retrieved from the Web of Science Core Collection database (WoSCC). We used the WoSCC and CiteSpace to analyze publication outcomes, journals, research direction, research hotspots, and frontiers. Overall, 4580 publications on DFUs were retrieved until March 22, 2018. The number of publications from the United States accounts for approximately one third of all publications from the top 10 countries. Surgery accounted for the largest proportion of the publications we retrieved from the WoSCC in terms of research areas. Results of this analysis indicated that DFU research has been in a stable, mature stage. Developed countries pay more attention to DFU research field than do developing countries, especially the United States. The complications of DFUs, such as lower extremity amputation and diabetic foot infection, are the hotspots. Diabetic foot infection, wound management, prediction studies on DFU, and diseases related to DFU are the research frontiers that should be observed closely in the future.
    Keywords:  CiteSpace; co-citation; diabetes; frontiers; hotspots
    DOI:  https://doi.org/10.1053/j.jfas.2018.08.052
  8. Br J Neurosurg. 2019 Jan 12. 1-5
       PURPOSE: There is an abundance of articles published on low-grade glioma. The aim of this study was to identify and review the 50 most-cited articles on low-grade glioma, and to perform a bibliometric analysis.
    METHODS: In June 2017, we performed a basic search of the Web of Science database using "low-grade glioma management and/or treatment" as our search terms without publication date restrictions. The top 50 most-cited articles were obtained and reviewed.
    RESULTS: The top 50 most-cited articles received a mean 195 citations per paper, with 571 citations being the most and 81 citations being the least. Publication dates ranged from 1992 to 2013. The articles were published in 17 journals and Journal of Neurosurgery published the greatest number of articles (10 of 50), followed by Journal of Clinical Oncology (9 of 50). The most frequent study categories were natural history studies (19 of 50) and laboratory studies (13 of 50). Neurosurgery as a specialty contributed to 22 articles. The majority of the articles originated in the United States (44%).
    CONCLUSION: We identified the top 50 most-cited articles on low-grade glioma and the level of knowledge about this topic has been increased.
    Keywords:  Analysis; articles; bibliometric; citation; low-grade glioma; neurosurgery
    DOI:  https://doi.org/10.1080/02688697.2018.1549314
  9. PeerJ. 2019 ;6 e6178
       Background: Researches on artificial livers greatly contribute to the clinical treatments for liver failure. This study aimed to evaluate the research output of artificial livers and citations from 2004 to 2017 through a bibliometric analysis.
    Methods: A list of included articles on artificial livers were generated after a comprehensive search of the Web of Science Core Collection (from 2004 to 2017) with the following basic information: number of publications, citations, publication year, country of origin, authors and authorship, funding source, journals, institutions, keywords, and research area.
    Results: A total of 968 included articles ranged from 47 citations to 394 citations with a fluctuation. The publications were distributed in 12 countries, led by China (n = 212) and the US (n = 207). There were strong correlations of the number of citations with authors (r 2 = 0.133, p < 0.001), and countries (r 2 = 0.275, p < 0.001), while no correlations of the number of citations with the years since publication (r 2 = 0.016, p = 0.216), and funding (r 2 < 0.001, p = 0.770) were identified. Keyword analysis demonstrated that with the specific change of "acute liver failure," decrease in "bioartificial livers" and "hepatocyte," and increase in "tissue engineering" were identified. The top 53 cited keyword and keyword plus (including some duplicates counts) were identified, led by bioartificial liver (405 citations) and hepatocyte (248 citations). The top 50 cited keywords bursts were mainly "Blood" (2004-2008), "hepatocyte like cell" (2008-2015), and "tissue engineering" (2014-2017). All keywords could be classified into four categories: bioartificial livers (57.40%), blood purification (25.00%), clinical (14.81%), and other artificial organs (2.78%).
    Discussion: This study shows the process and tendency of artificial liver research with a comprehensive analysis on artificial livers. However, although it seems that the future of artificial livers seems brighter for hepatocyte transplantation, the systems of artificial livers now are inclined on focusing on blood purification, plasma exchange, etc.
    Keywords:  Artificial livers; Bibliometric analysis; Citations; Keyword
    DOI:  https://doi.org/10.7717/peerj.6178
  10. BMC Res Notes. 2019 Jan 18. 12(1): 32
       OBJECTIVES: Evaluation of published research in a region provides insight into relevant aspects of clinical care and research priorities. This study aimed to provide a comprehensive assessment of the type of critical care research published in the World Health Organization Eastern Mediterranean region (EMR) over a 10-year period.
    RESULTS: During the study period (2007-2016), the search strategy revealed 4303 publications, of which 1537 were included in the analysis; studies were excluded for the following reasons: not critical care, conducted in non-EMR countries, editorials, case reports, in-vitro or animal studies, as well as those conducted in multiple countries and those that evaluated foreign military personal. Countries varied in the number of publications produced, ranging from none in Somalia to 620 in Iran. The majority of the studies were observational (78%), evaluated adults (73%), and the most common areas of research were infectious (29%) and respiratory (10%) diseases. Median sample size was 120 and the mean (SD) impact factor of the journals in which the articles were published was 1.02 (0.7).
    Keywords:  Critical care; Developing countries; Eastern Mediterranean; Research; Research output; Research productivity
    DOI:  https://doi.org/10.1186/s13104-019-4093-7
  11. JAMA Netw Open. 2018 Jul 06. 1(3): e180802
       Importance: Most pediatricians are women; however, women pediatricians are underrepresented in academic leadership positions such as department chairs and journal editors and among first authors of original research articles published in pediatric journals. Publication of all types of articles, particularly in high-impact specialty journals, is crucial to career building and academic success.
    Objective: To examine the gender-related profile associated with authors of perspective-type articles in the 4 highest-impact general pediatric journals to determine whether women physicians were similarly underrepresented.
    Design and Setting: Cross-sectional study of perspective-type articles published between 2013 and 2017 in the 4 highest-impact general pediatric journals: Academic Pediatrics, JAMA Pediatrics, The Journal of Pediatrics, and Pediatrics.
    Main Outcomes and Measures: The primary outcome measure was the number and percentage of first-author women physicians as compared with men physicians. Secondary outcome measures included number and percentage of all men and all women among last authors and coauthors associated with physician first authors.
    Results: A total of 425 perspective-type articles were identified, with physicians listed as the first author on 338 (79.5%). Women were underrepresented among physician first authors of known gender (140 of 336 [41.7%]), particularly among physician first authors of article categories described as scholarly (range, 15.4%-44.1%) vs categories described as narrative (range, 52.9%-65.6%) in nature. Women were also underrepresented among last authors and coauthors of articles attributed to both men and women physician first authors, although the underrepresentation of women among last authors and coauthors was more pronounced if a man physician was the first author.
    Conclusions and Relevance: Because perspective-type articles provide an opportunity for authors to express their opinions, provide insights that may influence their field, and enhance their academic resumes, there is a need for pediatric journal editors and leaders of medical societies who are associated with these journals to ensure the equitable inclusion of women in medicine. A hallmark of best practices for diversity and inclusion in academic medicine is transparency with regard to reporting of gender disparities in all areas of scholarship attribution and credit.
    DOI:  https://doi.org/10.1001/jamanetworkopen.2018.0802
  12. J Cardiothorac Vasc Anesth. 2018 Nov 16. pii: S1053-0770(18)31035-8. [Epub ahead of print]
       OBJECTIVE: Gender-based differences in scholarship among cardiothoracic anesthesiologists have not been studied. The authors examined the gender distribution of authorship of original research articles, case reports, review articles, and editorials in the Journal of Cardiothoracic and Vascular Anesthesia (JCVA) originating from the United States during four 3-year intervals to determine temporal changes in productivity of women in cardiothoracic anesthesiology. The authors tested the hypothesis that scholarly output of women has increased progressively in JCVA over time concomitant with greater participation in first, last, and corresponding author roles.
    DESIGN: Observational study.
    SETTING: Internet analysis.
    PARTICIPANTS: Authors of research articles, case reports, review articles, and editorials published in JCVA in 1990-92, 1999-2001, 2008-10, and 2015-17.
    INTERVENTIONS: None.
    MEASUREMENTS AND MAIN RESULTS: The gender of each author was determined by inspection of the first name. If gender could not be established easily, the author's institutional website was examined or an internet search using the Google search engine was conducted. First, last, and corresponding authors as well as coauthors were noted for each article. A total of 1,195 publications with 4,982 authors (1,032 women; 20.7%) were examined. Gender was identified positively in 98.5% of authors. Women were first, last, and corresponding authors on 22.4%, 10.3%, and 14.6% of publications, respectively. The percentage of women who were authors increased from 12.1% in 1990-92 to 20.9% in 1999-2001 (p < 0.05), but plateaued in 2008 to 2010 (22.3%) and 2015 to 2017 (22.9%). Greater percentages of women were first authors (26.2%), senior authors (11.8%), and corresponding authors (16.6%) in 2015 to 2017 compared with 1990 to 1992 (9.6%, 7.0%, and 8.7%, respectively; p < 0.05 for each). The contributions of women to research articles and case reports were primarily responsible for these observed increases, although women also made a substantial impact with review articles in 2015 to 2017. The percentage of publications that included at least 1 female author in any capacity increased in a time-dependent manner (p < 0.05) from 31.0% (1990-1992) to 74.4% (2015-2017). The proportion of female first or last authors (35.0%) appearing in JCVA during 2015 to 2017 was modestly higher than the current percentage of female cardiothoracic anesthesiologists practicing in departments with accredited fellowship programs (29.1%).
    CONCLUSION: The results indicate that scholarly output of women rose in JCVA over time, but gains in productivity have plateaued more recently. These findings are encouraging, but women continue to be underrepresented in corresponding and last author roles.
    Keywords:  cardiothoracic anesthesiology; fellowship training; leadership; productivity; promotion; rank and tenure; scholarship; women in academic medicine
    DOI:  https://doi.org/10.1053/j.jvca.2018.11.017