bims-myxlip 2026-06-14 papers

Issue of 2026–06–14
two papers selected by
Laura Mannarino, Humanitas Research

Oxf Med Case Reports. 2026 Jun;2026(6): omag091

Retroperitoneal myxoid liposarcoma in a 3.5-year-old Afghan child: a case report and review of the literature.

Myxoid liposarcoma is a malignant soft tissue sarcoma of adipocytic origin that predominantly affects adolescents and young adults. It is exceptionally rare in early childhood, with very few reported cases in children under the age of five. We present a rare case of a 3.5-year-old male child who was admitted to our emergency unit with a large abdominal mass. The patient underwent an exploratory laparotomy with complete excision of the mass, achieving negative surgical margins. Histopathological analysis confirmed the diagnosis of well-differentiated myxoid liposarcoma. The patient subsequently received six cycles of postoperative cyclophosphamide chemotherapy, administered at 20-day intervals. Follow-up tomography scan confirmed a favorable outcome with no evidence of recurrence.

Keywords: abdominal; chemotherapy; cyclophosphamide; laparotomy; liposarcoma; myxoid

DOI: https://doi.org/10.1093/omcr/omag091

Int J Surg Case Rep. 2026 Jun;138(6): 2126-2130

Cervical spine myxoid liposarcoma in a 30-year-old male: a rare case report.

Ibrahim Fathallah, Ahmed Al-Talep, Abd Alrhman Alajrd, Omar Alsabbagh, Ahmad Alhamoud.

Introduction and clinical importance: Myxoid liposarcoma (MLS) is a rare soft tissue sarcoma subtype, typically affecting adults. Spinal involvement is exceptionally uncommon, requiring careful diagnosis and management. We report a rare primary cervical spine case.
Case presentation: A 30-year-old man came to the neurology clinic transferred from a general surgeon with weakness and stiffness in both legs after a biopsy of a deep neck mass. He came to the general surgeon with a history of neck swelling with mild dysphagia. Magnetic resonance imaging (MRI) showed a large mass from C5 to T3 with spinal curvature. The surgeons removed the tumor, which turned out to be primary MLS. The patient regained full leg movement after physiotherapy and is currently receiving adjuvant therapy.
Clinical discussion: MLS develops from primitive mesenchymal cells rather than mature fat and can spread to unusual sites like the spine. MRI is valuable for diagnosis, and complete surgical removal is the main treatment, with radiotherapy or chemotherapy considered only when necessary.
Conclusion: This case emphasizes considering MLS in deep cervical masses and the importance of early treatment significantly contributed to the patient's full recovery.

Keywords: cervical spine; liposarcoma; myxoid liposarcoma

DOI: https://doi.org/10.1097/RC9.0000000000000047