Curr Biol. 2020 Jan 20. pii: S0960-9822(19)31530-1. [Epub ahead of print]30(2):
R83-R86
Two recent studies report that ZO proteins, the main scaffolding proteins of tight junctions, undergo liquid phase separation. This new concept provides understanding at the mechanistic level of how tight junctions are formed and how they participate in mechanochemical signaling in early development.