bims-evares Biomed News
on Evaluation of research
Issue of 2023‒11‒12
fifty-two papers selected by
Thomas Krichel, Open Library Society



  1. Clin Cosmet Investig Dermatol. 2023 ;16 3107-3120
      Background: Psoriasis is a global health concern as a chronic inflammatory skin disease. Endothelial dysfunction has been implicated in psoriasis pathogenesis.Objective: This study aims to explore the scientific literature on the relationship between psoriasis and endothelial cells using bibliometric analysis, identifying research trends and public interest in this topic.
    Methods: We analyzed articles on the topic of endothelial cells and psoriasis in the Web of Science (WoS) Core Collection from 1987 to 2022, examining their distribution by publication year, country, organization, author, and journal. We used bibliometric software, including CiteSpace and R package bibliometrix, to visualize co-authorship relations, keyword citation burst analysis, co citation networks, keyword time zone map, burst references and cluster analysis.
    Results: Our analysis included 993 publications. The bibliometric analysis revealed a steady increase in the number of publications on psoriasis and endothelial cells over the past decade. The United States was the leading contributor to this field. The Journal of Investigative Dermatology was the most high-yield publication journal. Burst references analysis identified key articles that have significantly influenced the field, including studies on the role of endothelial dysfunction in psoriasis pathogenesis and the association between psoriasis severity and cardiovascular outcomes. 9 clusters were grouped in the key-word citation network. "Expression", "inflammation", "endothelial growth factor" and "angiogenesis" were the research focuses, while "cardiovascular disease", "atherosclerosis", "endothelial dysfunction", and "oxidative stress" might be the future research hotspots.
    Conclusion: This bibliometric analysis sheds light on the growing acknowledgement of the involvement of endothelial cells in psoriasis, with the United States taking the lead. It also emphasizes the necessity for additional research to unravel the underlying mechanisms connecting psoriasis, endothelial dysfunction, and cardiovascular comorbidities. Ultimately, this research will contribute to the development of enhanced management strategies for psoriasis patients.
    Keywords:  bibliometric analysis; cardiovascular risk; endothelial cells; inflammation; molecular mechanisms; psoriasis
    DOI:  https://doi.org/10.2147/CCID.S435085
  2. Front Neurosci. 2023 ;17 1280180
      Background: Transcranial magnetic stimulation (TMS), as a non-invasive neuromodulation technique, has been widely used in the treatment of Parkinson's disease (PD). The increasing application of TMS has promoted an increasing number of clinical studies. In this paper, a bibliometric analysis of existing studies was conducted to reveal current research hotspots and guide future research directions.Method: Relevant articles and reviews were obtained from the Science Citation Index Expanded of Web of Science Core Collection database. Data related to publications, countries, institutions, authors, journals, citations, and keywords in the studies included in the review were systematically analyzed using VOSviewer 1.6.18 and Citespace 6.2.4 software.
    Result: A total of 1,894 papers on the topic of TMS in PD between 1991 and 2022 were analyzed and visualized to identify research hotspots and trends in the field. The number of annual publications in this field of study has increased gradually over the past 30 years, with the number of annual publications peaking in 2022 (n = 150). In terms of publications and total citations, countries, institutions, and authors from North America and Western Europe were found to make significant contributions to the field. The current hotspot focuses on the effectiveness of TMS for PD in different stimulation modes or different stimulated brain regions. The keyword analysis indicates that the latest research is oriented to the mechanism study of TMS for motor symptoms in PD, and the non-motor symptoms are also receiving more attention.
    Conclusion: Our study offers insights into the current hotspots and emerging trends of TMS in the rehabilitation of PD. These findings may serve as a guide for future research and the application of TMS for PD.
    Keywords:  Parkinson’s diseases; bibliometric analysis; hotspots; research trends; transcranial magnetic stimulation
    DOI:  https://doi.org/10.3389/fnins.2023.1280180
  3. Medicine (Baltimore). 2023 Nov 03. 102(44): e35764
      OBJECTIVE: Alzheimer disease (AD) is a major disease that affects the elderly worldwide. Therefore, this study aimed to examine the relationship between AD and sleep disorders, identify journal publications and collaborators, and analyze keywords and research trends using a bibliometric method.METHODS: Data retrieval is based on the Web of Science Core Collection database. CiteSpace V.6.1.R6 was used to analyze bibliometric analysis, calculate centrality, and draw co-occurrence maps of countries/regions, institutions, authors, published journals, cited literature, keyword co-occurrence maps, cluster maps, time graphs, and emergent maps from January 1986 to April 2023.
    RESULTS: There were 4677 publications relevant to AD and sleep disorders. From 1986 to 2023, the number of publications per year showed an increasing trend. The United States not only has the largest output of publications, the first in the centrality ranking, but also owns the 3 highest frequencies of publication institutions. The journal NEUROLOGY has the highest citation frequency, reaching 2671, with a median centrality value of 0.64. A comprehensive analysis of centrality showed that AD, circadian rhythm, dementia, Parkinson disease, sleep, and older adults are both high-frequency words and high centrality words, becoming core keywords in this field.
    CONCLUSIONS: This was the first study to provide an overview, about the current main status of development, hot spots of the study, and the future trends in sleep disorders and AD, which provides a comprehensive review of the trends and gaps in field of sleep and AD, and thus lays the groundwork for future research.
    DOI:  https://doi.org/10.1097/MD.0000000000035764
  4. Medicine (Baltimore). 2023 Nov 03. 102(44): e34455
      To analyze the status, hotspots, and frontiers of spine surgery in the geriatric using bibliometric method, the Web of Science Core Collection was searched for all papers concerning the use of spine surgery in the elderly from January 1, 1982 to August 3, 2022. VOSviewer and R software were used to perform the bibliometric analysis, which included retrieving the country, institution, author, journal, and keyword. A total of 663 articles were identified. The investigation revealed a growing number of publications over the past 20 years. The country with the highest number of publications was the United States (195 papers). The institution with the highest number of publications was the University of California (31 papers). H. Hassanzadeh and A. Jain were the most productive authors (14 publications), while R. A. Deyo was the most co-cited author. The journal with the most published papers was Spine (67 papers). According to Bradford Low, Spine, World Neurosurgery, and European Spine Journal were core journals in the field of geriatric spine surgery. The most recent trend topic was "readmission," "vertebroplasty," "kyphoplasty," "risk," "osteoporosis," "outcomes," "surgery," "complications," "scoliosis," and "management." In particular, osteoporosis has been a topic of attention in the field of geriatric spine surgery since 2005. Over time, research on spinal surgery in the elderly and allied topics has grown in importance and scope, indicating a tendency toward globalization. Researchers should pay more attention to the outcomes, complications, and management associated with spine surgery in the elderly.
    DOI:  https://doi.org/10.1097/MD.0000000000034455
  5. Medicine (Baltimore). 2023 Nov 03. 102(44): e35897
      BACKGROUND: Kampo medicine is a traditional medicine that originated in ancient China and has since developed as a uniquely Japanese medicine. Although Kampo medicine is one of Japan's most important therapeutic modalities and numerous papers have been published recently, information on current hotspots and trends in Kampo research is lacking. This bibliometric analysis of Kampo medicine surveyed the latest research hotspots and trends.METHODS: Articles on Kampo medicine were retrieved from the Web of Science Core Collection. We used medical subject headings related to Kampo medicine and searched for publications from 2013 to 2022. The retrieved articles were analyzed for countries, authors, journals, references, and keywords related to Kampo medicine using CiteSpace, VOSviewer, and SCImago Graphica.
    RESULTS: A total of 1170 articles were included. The number of Kampo medicine-related publications and citations has recently increased, mainly from Japan. Author Keiko Ogawa-Ochiai published the most papers (40 papers), while Yoshio Kase had the highest frequency at 663 citations. Among the co-cited authors, Toru Kono was the most cited and had the highest total link strength. The journal with the most submissions was Evidence-based Complementary and Alternative Medicine. A comprehensive keyword and literature analysis revealed the following research hotspots: "Yokukansan and behavioral and psychological symptoms of dementia," "Ninjinyoeito and geriatric care," "Daikenchuto and postoperative gastrointestinal cancer," and "Rikkunshito and functional dyspepsia." We also identified a new research frontier by identifying an association between hochuekkito and COVID-19.
    CONCLUSIONS: Our findings reveal trends in Kampo medicine research, with specific hotspots and the authors and publications with the largest research impact. Collecting a large volume of literature data, analyzing the impact of studies, and identifying research hotspots, as in this study, will provide researchers with future directions for Kampo research.
    DOI:  https://doi.org/10.1097/MD.0000000000035897
  6. Medicine (Baltimore). 2023 Nov 03. 102(44): e35727
      A growing number of studies have shown that gut microbiota (GM) plays an essential role in the occurrence and development of colorectal cancer (CRC). The current body of research exploring the relationship between CRC and GM is vast. Nevertheless, bibliometric studies in this area have not yet been reported. This study aimed to explore the hotspots and frontiers of research on GM and CRC in the past 20 years, which may provide a reference for researchers in this field. The Web of Science Core Collection database was searched for publications on CRC and GM from 2002 to 2022. The scientometric softwares CiteSpace and VOSviewer were used to visually analyze the countries, institutions, authors, journals, and keywords involved in the literature. Keywords co-occurrence, cluster, and burst analysis were utilized to further explore the current state and development trends of research on GM and CRC. A total of 2158 publications were included in this study, with a noticeably rising annual publication trend. The majority of these papers are from 80 nations, primarily China and the USA. J Yu was the most active author and WS Garrett has the highest citation. Among all institutions, Shanghai Jiao Tong University has the largest number of papers. Most of the publications were published in the International Journal of Molecular Sciences, with Science being the most frequently cited journal. The 4 main clusters mainly involved probiotics, inflammation, molecular mechanisms, and research methods. Current research hotspots included "Fusobacterium nucleatum," "Escherichia coli," etc. Newly emerging research has focused predominantly on immune response, gene expression, and recent strategies for the treatment of CRC with GM. The relationship between GM and CRC will continue to be a hot research area. Changes in the composition of GM in patients with CRC, the potential molecular mechanisms as well as probiotics and natural products used in the treatment of CRC have been the focus of current research and hotspots for future studies.
    DOI:  https://doi.org/10.1097/MD.0000000000035727
  7. Medicine (Baltimore). 2023 Nov 03. 102(44): e35758
      BACKGROUND: We used bibliometric methods to evaluate publications on the role of nutrition in sarcopenic obesity and analyzed the current situation and developmental trends over the past 2 decades.METHODS: Publications from 2002 to 2022 related to the role of nutrition in sarcopenic obesity were extracted from the Web of Science Core Collection database. CiteSpace, VOSviewer, and the Bibliometrix R package were applied to build relevant network diagrams.
    RESULTS: One thousand ninety-four articles from 64 countries were included. The annual number of publications in this field has shown an intense growth trend. The University of Alberta, Yonsei University, and Korea University are the major research institutions. Clinical Nutrition has published the most papers on the role of nutrition in sarcopenic obesity, and the American Journal of Clinical Nutrition is the most co-cited journal. A total of 5834 authors conducted the relevant studies. Yves Boirie has published the most papers in this field, and AJ Cruz-Jentoft is the most co-cited author.
    CONCLUSION: This is the first bibliometric study of the role of nutrition in sarcopenic obesity. This study systematically summarizes the research hotspots and development directions in this field, and provides a reference for scholars studying the role of nutrition in sarcopenic obesity.
    DOI:  https://doi.org/10.1097/MD.0000000000035758
  8. J Pain Res. 2023 ;16 3655-3671
      Context: Pain management is a constant struggle. Transcranial direct current stimulation (tDCS) is a neuromodulation technique with proved efficacy in chronic pain.Objective: The aim of the study is to provide a bibliometric perspective regarding articles on pain and tDCS. Having a visualized and systematically overview of publication trends, new research ideas could arise for clinicians.
    Methods: Articles on pain and tDCS were retrieved from Web of Science database. Using the R software version 4.1.2 and the "biblioshiny" R package, a quantitative and statistical analysis was performed. Time trend, number of publications, journals and authors, author country and institution, as well as citations and references were visualized.
    Results: A total of 554 publication fulfilled the criteria and were analyzed. The scientific production has been increasing over time with an annual growth of 17.1%. Brain Stimulation Journal and Journal of Pain are the leading journals regarding articles and citations. Fregni F. (83 articles) is the most prolific researcher with important authorship in the field. USA is the country with most authors involved in the topic (558 authors), whereas the leading institution is represented by Universidade Federal Rio Grande Do Sul (84 articles). Lefaucheur JP. article from 2017 has the maximum citations, while keywords in trend in the last three years are osteoarthritis and low back pain.
    Conclusion: This is the first bibliometric study that reflects the trends of tDCS in the field of pain. Journals as well as authors are limited and clustered. However the number of articles as well as number of citations are constantly increasing, supporting the idea that this is an emerging topic. The information obtained could be an important practical basis for future pain management research.
    Keywords:  Web of Science; bibliometric analysis; chronic pain; neuromodulation; noninvasive electric brain stimulation
    DOI:  https://doi.org/10.2147/JPR.S427658
  9. Endocrinol Diabetes Metab. 2023 Nov 08. e460
      BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a metabolic syndrome of the liver, and its incidence is increasing worldwide. Accumulating evidence suggests that bile acids are associated with NAFLD. Although many studies on bile acids and NAFLD have been published over the past 20 years, the authors of this study have not found a relevant bibliometric analysis in this field. Therefore, this study aimed to evaluate the trend of publications, summarize current research hotspots and predict future research directions through bibliometric analysis in this field.METHOD: Articles related to bile acids and NAFLD published between 2002 and 2022 were obtained from the Science Citation Index-Expanded of Web of Science Core Collection. Microsoft Excel, CiteSpace, VOSviewer and Bibliometric Online Analysis Platform were used to analyse the publication trends and research hotspots in this field.
    RESULTS: Among the articles published between 2002 and 2022, we retrieved 1284 articles related to bile acids and NAFLD, and finally included 568 articles. The USA was dominant until 2020, after which China surpassed the USA to become the dominant force. These two countries cooperate the most closely, and are also the most active in international cooperation. The University of California (UCL) was the most published institution, with a total of 31 publications. There were six authors who have published nine articles and ranked first. The keywords cluster labels show the 10 main clusters: #0fatty liver, #1obeticholic acid, #2oxidative stress, #37 alpha hydroxy 4 cholesten 3 one, #4deoxycholic acid, #5nonalcoholic fatty liver disease, #6mouse model, #7fibroblast growth factor 21, #8animal models, #9high-fat diet. Keywords burst analysis revealed a higher intensity of study for the nuclear receptor, FXR, and metabolic syndrome.
    CONCLUSION: Bile acids have become an important research direction in the field of NAFLD, and the intervention of gut microbiota in NAFLD by acting on bile acids may become a potential hotspot for future research. This study provides reference and guidance for future research, and will help scholars better explore the field and innovatively discover the mechanisms and treatments of NAFLD.
    Keywords:  NAFLD; bibliometric analysis; bile acids; cluster; hotspots
    DOI:  https://doi.org/10.1002/edm2.460
  10. Front Neurosci. 2023 ;17 1275748
      Background: Dysphagia represents one of the common complications following a stroke, and post-stroke dysphagia (PSD) can lead to aspiration, pneumonia, and malnutrition, thus prolonging hospital stay, escalating medical expenditures, and imposing a substantial economic strain on both patients and society. The utilization of bibliometric analysis offers a quantitative approach for investigating the existing literature and recognizes the current status of the research. However, bibliometric analysis on the subject of PSD remains absent. Consequently, we carried out this study to provide researchers with insights, facilitating their further exploration of PSD.Methods: Conducting a bibliometric analysis of articles pertaining to PSD retrieved over the past two decades enables us to acquire the research hotspots and trends in this area. The publications concerning PSD were searched from the Core Collection of Web of Science, spanning the period ranging from 2003 to 2023. Articles or reviews published in English were included in this study. Subsequently, we employed CiteSpace and VOSviewer software to visualize the retrieved articles, thereby identifying the cooperative relationships of authors, institutions, and countries, as well as relevant information about journals and references.
    Results: This study comprised 866 papers in total, and the number of articles published each year shows an overall growth trend. As for the analysis of the authors, Dziewas R. was the most prolific author with 21 articles. The most frequently published institutions, countries, and journals were the University of Manchester, China, and Dysphagia, with 28, 254, and 75 publications, respectively. And the co-cited authors and journals with the highest counts were Martino R and Stroke. According to the analysis of keywords and references, dysphagia screening and assessment, prevention of pneumonia, rehabilitation approaches, and nutritional management of PSD are considered research hotpots. Additionally, future research may focus on the topics of systematic review and meta-analysis, noninvasive brain stimulation, and lesion location.
    Conclusion: Through the bibliometrics analysis of PSD, we can capture the research hotspots and frontiers of PSD, thereby providing inspiration and reference for subsequent studies in this field.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; post-stroke dysphagia; stroke
    DOI:  https://doi.org/10.3389/fnins.2023.1275748
  11. BMC Public Health. 2023 Nov 09. 23(1): 2208
      BACKGROUND: Exposure to environmental tobacco smoke (ETS) is arguably the most ubiquitous and hazardous, even at very low levels, starting in early life. The objective of this study was to describe the state of research and future trends on ETS exposure and Children's Health (CH) topics with bibliometrics and altmetrics.METHODS: An electronic search was performed in Scopus database on January 31, 2023. Consensus was arrived on 100 most-cited articles by two reviewers. These papers were then cross matched with citations harvested from Web of Science (WoS) and Google Scholar. Altmetric Attention Score (AAS) and Dimension counts were also collected. Analysis and network visualization of authors, countries, and keywords were generated using VOSviewer software.
    RESULTS: Among a total of 1107 articles published on ETS and CH, the 100 top-cited articles appeared in 54 journals, with Pediatrics (n = 12) contributing a maximum number of articles. The time period between 2000 and 2009 accounted for 44% of all publications. With respect to the research design employed across these studies, cross-sectional design took precedence over others accounting for approximately 40%. Predominantly, articles focused on childhood asthma; however, current research trends have shifted towards emerging fields such as children's oral health and DNA methylation. Twitter, policy documents, and news outlets were the main platforms where outputs were discussed. The AAS was not associated with journal impact factor or access type. Weak correlations were observed between AAS and citation count in Scopus, WoS, and Google Scholar (r = 0.17 to 0.27) while a positive association existed between dimension count and the number of citations across all three databases (r = 0.84 to 0.98).
    CONCLUSION: This study demonstrates the evolution, digital dissemination and research hotspots in the field of ETS and CH, predicting the possible future research directions. High-quality studies with more specific exposure classification are warranted to better understand the relationship between ETS and CH.
    Keywords:  Altmetric; Bibliometric analysis; Child health; Dimensions; Environmental tobacco smoke; Most cited
    DOI:  https://doi.org/10.1186/s12889-023-16242-1
  12. Medicine (Baltimore). 2023 Nov 03. 102(44): e34801
      BACKGROUND: Skin cancers (SCs) arise due to the proliferation of atypical cells that have the potential to infiltrate or metastasize to different areas of the body. There is a lack of understanding regarding the country-based collaborations among authors (CBCA) and article themes on SCs. A clustering algorithm capable of categorizing CBCA and article themes on skin cancer is required. This study aimed to apply a follower-leading clustering algorithm to classify CBCA and article themes and present articles that deserve reading in recent ten years.METHODS: Between 2013 and 2022, a total of 6526 articles focusing on SC were extracted from the Web of Science core collection. The descriptive, diagnostic, predictive, and prescriptive analytics model was employed to visualize the study results. Various visualizations, including 4-quadrant radar plots, line charts, scatter plots, network charts, chord diagrams, and impact beam plots, were utilized. The category, journal, authorship, and L-index score were employed to assess individual research achievements. Diagnostic analytics were used to cluster the CBCA and identify common article themes. Keyword weights were utilized to predict article citations, and noteworthy articles were highlighted in prescriptive analytics based on the 100 most highly cited articles on SC (T100SC).
    RESULTS: The primary entities contributing to SC research include the United States, the University of California, San Francisco in US, dermatology department, and the author Andreas Stang from Germany, who possess higher category, journal, authorship, and L-index scores. The Journal of the American Academy of Dermatology has published the highest number of articles (n = 336, accounting for 5.16% of the total). From the T100SC, 7 distinct themes were identified, with melanoma being the predominant theme (92% representation). A strong correlation was observed between the number of article citations and the keyword weights (F = 81.63; P < .0001). Two articles with the highest citation counts were recommended for reading.
    CONCLUSION: By applying the descriptive, diagnostic, predictive, and prescriptive analytics model, 2 noteworthy articles were identified and highlighted on an impact beam plot. These articles are considered deserving of attention and could potentially inspire further research in the field of bibliometrics, focusing on relevant topics related to melanoma.
    DOI:  https://doi.org/10.1097/MD.0000000000034801
  13. Curr Med Res Opin. 2023 Nov 08. 1-11
      A bibliometric analysis (BA) is a knowledge synthesis methodology aimed at quantitively summarizing large amounts of bibliometric data. We aimed to summarize the performance of BAs in the health sciences. We searched Scopus for BAs in the health sciences published prior to May 10th, 2023. All identified studies were included. We performed a BA on these studies in two steps: performance analysis and science mapping. For the performance analysis, various indicators of scientific production were calculated using the bibliometrix R package. For the science mapping, VOSviewer was used to generate a co-authorship network and a keyword co-occurrence network. In total, 5828 BAs were analyzed. Scientific production has exploded in the last years, with more than 1500 BAs published in 2022 alone. Scientific impact (i.e., citations) has also been rising, although at a lesser pace. The mean number of citations per year per BA was 1.78. China was the most productive country, publishing more BAs than the nine other most productive countries combined. China paradoxically had a lower number of citations per publication compared with the nine other most productive countries. International collaborations were rare. Common BA themes included oncology, public health, neurosciences, mental health, artificial intelligence, and COVID-19. BAs are increasingly common in the health sciences, but their performance remains limited. More international collaborations and standardized guidelines could help improve their performance, notably the frequency at which they are cited.
    Keywords:  bibliometrics; knowledge synthesis; medicine; scientometrics; trends
    DOI:  https://doi.org/10.1080/03007995.2023.2281503
  14. Hum Vaccin Immunother. 2023 Dec 15. 19(3): 2274220
      Intervertebral disc degeneration is an important pathological basis for spinal degenerative diseases. The imbalance of the immune microenvironment and the involvement of immune cells has been shown to lead to nucleus pulposus cells death. This article presents a bibliometric analysis of studies on immune cells in IDD in order to clarify the current status and hotspots. We searched the WOSCC, Scopus and PubMed databases from 01/01/2001 to 08/03/2023. We analyzed and visualized the content using software such as Citespace, Vosviewer and the bibliometrix. This study found that the number of annual publications is increasing year on year. The journal study found that Spine had the highest number of articles and citations. The country/regions analysis showed that China had the highest number of publications, the USA had the highest number of citations and total link strength. The institutional analysis found that Shanghai Jiao Tong University and Huazhong University of Science Technology had the highest number of publications, Tokai University had the highest citations, and the University of Bern had the highest total link strength. Sakai D and Risbud MV had the highest number of publications. Sakai D had the highest total link strength, and Risbud MV had the highest number of citations. The results of the keyword analysis suggested that the current research hotspots and future directions continue to be the study of the mechanisms of immune cells in IDD, the therapeutic role of immune cells in IDD and the role of immune cells in tissue engineering for IDD.
    Keywords:  Immune cells; Scopus; bibliometric analysis; immune response; intervertebral disc degeneration; web of science
    DOI:  https://doi.org/10.1080/21645515.2023.2274220
  15. J Pain Res. 2023 ;16 3673-3691
      Purpose: Electroacupuncture is widely used to pain management. A bibliometric analysis was conducted to identify the hotspots and trends in research on electroacupuncture for pain.Methods: We retrieved studies published from 1994-2022 on the topic of pain relief by electroacupuncture from the Web of Science Core Collection database. We comprehensively analysed the data with VOSviewer, CiteSpace, and bibliometrix. Seven aspects of the data were analysed separately: annual publication outputs, countries, institutions, authors, journals, keywords and references.
    Results: A total of 2030 papers were analysed, and the number of worldwide publications continuously increased over the period of interest. The most productive country and institution in this field were China and KyungHee University. Evidence-Based Complementary and Alternative Medicine was the most productive journal, and Pain was the most co-cited journal. Han Jisheng, Fang Jianqiao, and Lao Lixing were the most representative authors. Based on keywords and references, three active areas of research on EA for pain were mechanisms, randomized controlled trials, and perioperative applications. Three emerging trends were functional magnetic resonance imaging (fMRI), systematic reviews, and knee osteoarthritis.
    Conclusion: This study comprehensively analysed the research published over the past 28 years on electroacupuncture for pain treatment, using bibliometrics and science mapping analysis. This work presents the current status and landscape of the field and may serve as a valuable resource for researchers. Chronic pain, fMRI-based mechanistic research, and the perioperative application of electroacupuncture are among the likely foci of future research in this area.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; blibliometrix; electroacupuncture; pain
    DOI:  https://doi.org/10.2147/JPR.S422614
  16. Front Cardiovasc Med. 2023 ;10 1260569
      Objective: To investigate development trends and research hotspots of exercise for hypertension research and provide researchers with fresh perspectives for further studies.Materials and methods: Articles and reviews regarding exercise and hypertension spanning May 1st 2003 to May 18th 2023 were retrieved from the Web of Science Core Collection (WOSCC) database. VOSviewer and Citespace were mainly used to perform and visualize co-authorship, co-citation, and co-occurrence analysis of countries, institutions, authors, references and keywords in this field.
    Results: A total of 1,643 peer-reviewed papers were identified, displaying a consistent increasing trend over time. The most prolific country and institution were Brazil and University of Sao Paulo, respectively. And we identified the most productive author was lrigoyen, Maria Claudia C, while Pescatello Linda S was the most co-cited author. Journal of hypertension was the most prominent journal, and Hypertension was the journal which was the most co-cited. And this field can be divided into 3 research themes: exercise interventions for hypertension, age-specific relevance of exercise for hypertension, and the global burden of hypertension and the role of exercise. According to the result of keywords analysis, epidemiological information, types of exercise, target population, mechanism, and study design are significant research areas. "Resistance training", "adults", and "heart rate variability" were identified as the major future research foci.
    Conclusions: The findings offer a scientific insight into exercise for hypertension research, presenting researchers with valuable information to understand the current research status, hotspots, and emerging trends for future investigation.
    Keywords:  CiteSpace; high blood pressure; hypertension management; non-pharmacological intervention; research hotspots
    DOI:  https://doi.org/10.3389/fcvm.2023.1260569
  17. Dermatology. 2023 Nov 08.
      BACKGROUND: Alopecia areata (AA) is an autoimmune disorder characterized by hair loss on the scalp, face, and other body areas. Despite affecting approximately 2% of the global population, there has been no previous bibliometric analysis specifically focusing on AA treatment, that can guide researchers in exploring promising treatment options and directing future research efforts.SUMMARY: This study conducted a bibliometric analysis of AA treatment research, encompassing publications from 2003 to 2022. A total of 1323 papers from 65 countries, predominantly led by the United States and China, were included in the analysis. The number of publications related to AA treatment showed a notable increase over the years. Prominent research institutions included the University of Manchester, Icahn School of Medicine at Mount Sinai, University of Miami, and Columbia University. Among the journals, Dermatologic Therapy stood out as the most popular, while the Journal of the American Academy of Dermatology appeared as the most frequently co-cited publication.
    KEY MESSAGES: 1. This bibliometric study provides a comprehensive overview of the research trends and advancements in AA treatment. 2. The analysis identified key research hotspots, including variants, platelet-rich plasma (PRP), janus kinase (JAK) inhibitors, and regulatory T (Treg) cells. 3. Researchers specializing in AA can use these findings as a valuable reference to augment their study and explore new avenues for research in treating AA.
    DOI:  https://doi.org/10.1159/000535043
  18. Cureus. 2023 Oct;15(10): e46384
      Background Orthopedic surgery has become an increasingly competitive specialty. With a pass-fail Step 1, an even greater emphasis on research has been placed to allow candidates to better distinguish themselves. This study analyzes the scholarly activity of accepted orthopedic residency applicants during medical school, assessing what factors, including the novel altmetric attention score, may be associated with greater research productivity. Methods A list of orthopedic residency programs was obtained from the Electronic Residency Application Service (ERAS). A total of 688 orthopedic residents from 180 programs who matriculated in 2020 from allopathic medical schools were identified. Resident demographic information and bibliometric data (total publications, orthopedic-related publications, h-index, and altmetric score) of publications published from July 1, 2016, to September 1, 2020, were collected. Descriptive statistics were calculated. Kruskal-Wallis tests analyzed the association between medical school characteristics and research productivity using Stata® 17.0 (StataCorp LLC, College Station, Texas). Results Postgraduate-Year-3 orthopedic residents (N=688) published 2,600 articles during medical school, averaging 3.8 articles per resident. The residents from a top 25 medical school for research had publication counts, altmetric scores, and h-indices, on average, that were higher than those from non-top 25 medical schools for research. Over 150 residents had no publications, and ~10 residents had more than 30 publications. Conclusions The results illustrate that medical school research status influences the research productivity of applicants. Also, given the average number of publications, most research listed on applications are abstracts and presentations. Utilization of the altmetric score may not yet be the best way of examining research experience because orthopedic applicants do not appear to use social networks for academic research.
    Keywords:  altmetric attention score; altmetric score; medical student education; orthopedic residency; publication count; research productivity; residency applications; undergraduate medical education
    DOI:  https://doi.org/10.7759/cureus.46384
  19. Front Pharmacol. 2023 ;14 1282090
      Background: Acquired immunodeficiency syndrome (AIDS) has seriously endangered human life and health, the main pathogenic agent is human immunodeficiency virus type 1 (HIV-1). The combination antiretroviral therapy (cART) has shown serious drug resistance and side effects, and the discovery of HIV-1 capsid inhibitors is an effective way to solve the problem. Recent studies have shown significant progress in the research of HIV-1 capsid inhibitors. However, there is still a lack of comprehensive overview of bibliometric analysis in this field. This study aimed to provide the research trends and hotspots of HIV-1 capsid inhibitors. Method: Publications related to HIV-1 capsid inhibitors from 2000 to 2022 were searched on the Web of Science Core Collection (WoSCC) database and screened according to inclusion criteria. VOSviewer was conducted to evaluate the results. Results: 96 publications from 25 countries were finally included, and the number of annual publications related to HIV-1 capsid inhibitors showed an increasing trend. The United States was the most productive country with the most publication number, H-index, and total citation number, as well as the widest international cooperation. The most popular journal in this field was Journal of Virology. Drexel University was the most productive institution, and Simon Cocklin participated in the most publications. Keywords co-occurrence analysis exhibited that studying the molecular mechanism of capsid protein, discovering drug candidates, and improving antiretroviral therapy are the main and hot topics in this field. Conclusion: This is the first bibliometric study in the field of HIV-1 capsid inhibitors, which comprehensively analyzed the research trends and hotspots in this direction. This work is expected to provide the scientific community with new insights to promote the research of HIV-1 capsid inhibitors.
    Keywords:  HIV-1; VOSviewer; WoSCC; bibliometrics; capsid inhibitor
    DOI:  https://doi.org/10.3389/fphar.2023.1282090
  20. Front Microbiol. 2023 ;14 1239818
      Background: Gut microbiome is a complex community of microbes present in the human gut and plays an important role in the occurrence and progression of colorectal cancer (CRC). However, the relationship between virus and CRC has not been fully understood.Objective: To explore the hot spots and research trends in the field of CRC and virus.
    Methods: By using the bibliometric analysis tool CiteSpace and based on the articles of the Web of Science Core Collection (WoSCC) database, the country, institution, highly cited literature, keywords and so on were visually analyzed.
    Results: A total of 356 research articles on CRC from 2001 to 2023 were thoroughly analyzed. The USA and China have made the largest contribution in the field of virus and CRC. The Helmholtz Association published the most papers. There were relatively few cooperations among institutions from different countries. The results of keyword cluster analysis proved that the literature on the relationship between human cytomegalovirus (CMV) and CRC was the most widely studied aspect in this field. "Gut microbiota," "inflammatory bowel disease," "hepatitis b virus," and "human papillomavirus infection" are the current research hotspots; "oncolytic virus," "apoptosis," and "gut microbiome" are the recent research frontiers and should be paid closer attention.
    Conclusion: By using CiteSpace bibliometric software, the visual analysis reflected the research trends and hot topics of virus and CRC. In addition, the prevalence and mechanism of specific virus on CRC were also reviewed, which provides valuable references for future CRC research.
    Keywords:  bacteriophage; bibliometric; colorectal cancer; gut microbiota; virus
    DOI:  https://doi.org/10.3389/fmicb.2023.1239818
  21. RSC Adv. 2023 Oct 31. 13(46): 32699-32712
      Lignocellulosic biomass (LCB) stands as a substantial and sustainable resource capable of addressing energy and environmental challenges. This study employs bibliometric analysis to investigate research trends in lactic acid (LA) production from LCB spanning the years 1991 to 2022. The analysis reveals a consistent growth trajectory with minor fluctuations in LA production from LCB. Notably, there's a significant upswing in publications since 2009. Bioresource Technology and Applied Microbiology and Biotechnology emerge as the top two journals with extensive contributions in the realm of LA production from LCB. China takes a prominent position in this research domain, boasting the highest total publication count (736), betweenness centrality value (0.30), and the number of collaborating countries (42), surpassing the USA and Japan by a considerable margin. The author keywords analysis provides valuable insights into the core themes in LA production from LCB. Furthermore, co-citation reference analysis delineates four principal domains related to LA production from LCB, with three associated with microbial conversion and one focused on chemical catalytic conversion. Additionally, this study examines commonly used LCB, microbial LA producers, and compares microbial fermentation to chemical catalytic conversion for LCB-based LA production, providing comprehensive insights into the current state of this field and suggesting future research directions.
    DOI:  https://doi.org/10.1039/d3ra06577d
  22. Bioengineered. 2023 Dec;14(1): 2274150
      Transplantation of tissue-engineered trachea is an effective treatment for long-segment tracheal injury. This technology avoids problems associated with a lack of donor resources and immune rejection, generating an artificial trachea with good biocompatibility. To our knowledge, a systematic summary of basic and clinical research on tissue-engineered trachea in the last 20 years has not been conducted. Here, we analyzed the development trends of tissue-engineered trachea research by bibliometric means and outlined the future perspectives in this field. The Web of Science portal was selected as the data source. CiteSpace, VOSviewer, and the Bibliometric Online Analysis Platform were used to analyze the number of publications, journals, countries, institutions, authors, and keywords from 475 screened studies. Between 2000 and 2023, the number of published studies on tissue-engineered trachea has been increasing. Biomaterials published the largest number of papers. The United States and China have made the largest contributions to this field. University College London published the highest number of studies, and the most productive researcher was an Italian scholar, Paolo Macchiarini. However, close collaborations between various researchers and institutions from different countries were generally lacking. Despite this, keyword analysis showed that manufacturing methods for tracheal stents, hydrogel materials, and 3D bioprinting technology are current popular research topics. Our bibliometric study will help scientists in this field gain an in-depth understanding of the current research progress and development trends to guide their future work, and researchers in related fields will benefit from the introduction to transplantation methods of tissue-engineered trachea.
    Keywords:  Bibliometric analysis; hydrogel material; three-dimensional bioprinting; tissue engineering; tracheal transplantation
    DOI:  https://doi.org/10.1080/21655979.2023.2274150
  23. Cureus. 2023 Oct;15(10): e46497
      Propofol-related infusion syndrome (PRIS) is a rare, yet life-threatening sequelae to prolonged administration of the anesthetic propofol in mechanically intubated patients. The condition is characterized by progressive multi-system organ failure and eventual mortality; of note, the predominant characteristics of PRIS involve but are not limited to cardiovascular impairment and collapse, metabolic and lactic acidosis, rhabdomyolysis, hyperkalemia, and acute renal failure. While potent or extended doses of propofol have been found to be the primary precipitating factor of this condition, others such as age, critical illness, steroid therapy, and hyperlipidemia have been discovered to play a role as well. This bibliometric analysis was done to reflect the current relevance and understanding of PRIS in recent literature. The SCOPUS database was utilized to conduct a search for articles with keywords "propofol infusion syndrome" and "propofol syndrome" from February 24, 2001, until April 16, 2023, with parameters for article title, citation number, citation per year, author, institution, publishing journal, and country of origin. PRIS was first defined in 1990, just a year after its approval by the Food and Drug Administration for use as a sedative-hypnotic. Since then, interest in PRIS slowly rose up to 13 publications per year in 2013. Seven papers on the topic were published in Critical Care Medicine, six in Neurocritical Care, and four in Anesthesia. The most common institutions were Mayo Clinic, Northeastern University, and Tufts Medical Center. To our knowledge, this is the first bibliometric analysis to evaluate the most influential publications about PRIS. A majority of the research is case-based, possibly owing to the rarity of the condition. Our research suggests that confounding factors outside the precipitating dosage of propofol may be implicated in the onset and progression of PRIS. This study could therefore bring renewed interest to the topic and lead to additional research focused on fully understanding the pathophysiology of PRIS in order to promote the development of novel diagnostics and treatment.
    Keywords:  bibliometric analysis; medical publications; propofol infusion syndrome; propofol syndrome; systematic review and meta analysis
    DOI:  https://doi.org/10.7759/cureus.46497
  24. Environ Pollut. 2023 Nov 07. pii: S0269-7491(23)01892-4. [Epub ahead of print] 122890
      Plastic pollution has become a global and persistent challenge, posing threats to ecosystems and organisms. In recent years, there has been a rapid increase in scientific research focused on understanding microplastics in the soil‒plant system. This surge is primarily driven by the direct impact of microplastics on agricultural productivity and their association with human activities. In this study, we conducted a comprehensive bibliometric analysis to provide an overview of the current research on microplastics in soil‒plant systems. We systematically analysed 192 articles and observed a significant rise in research interests since 2017. Notably, China has emerged as a leading contributor in terms of published papers, closely followed by Germany and the Netherlands. Through co-authorship network analysis, we identified 634 different institutions that participated in publishing papers in this field, with the Chinese Academy of Sciences having the most collaborations. In the co-occurrence keyword network, we identified four clusters focusing on the diversity of microplastics within the agroecosystem, transportation, and quantification of microplastics in soil, analysis of plastic contamination type and impact, and investigation of microplastic phytotoxicity. Furthermore, we identified ten research priorities, categorized into the effects of microplastics in "soil" and "plant". The research hotspots were found to be due to the effect of microplastics on soil physicochemical properties and the synergistic phytotoxicity of microplastics with other pollutants. Overall, this bibliometric analysis holds significant value, serving as an important reference point and offering valuable suggestions for future researchers in this rapidly advancing field.
    Keywords:  Bibliometric analysis; Co-contamination of microplastics; Fate of microplastics; Microplastic phytotoxicity; Plastisphere
    DOI:  https://doi.org/10.1016/j.envpol.2023.122890
  25. J Neurosurg. 2023 Nov 03. 1-7
      OBJECTIVE: The American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Joint Cerebrovascular (CV) Section serves as a centralized entity for the dissemination of information related to CV neurosurgery. The quality of scientific conferences, such as the CV Section's Society of NeuroInterventional Surgery Annual Meeting, can be gauged by the number of poster and oral presentations that are published in peer-reviewed journals. However, publication rates from the CV Section's meetings are unknown. The objective of this study was to assess the rate at which abstracts presented at the AANS/CNS CV Section Annual Meeting from 2014 to 2018 were subsequently published in peer-reviewed journals.METHODS: The abstract titles for all accepted poster and oral podium presentation abstracts from the 2014-2018 Annual Joint AANS/CNS CV Section Meetings were searched using PubMed. A match was defined as sufficient similarity between the abstract and its corresponding journal publication with regard to title, authors, methods, and results. Five-year impact factors (IFs) from Journal Citation Reports (JCR), the country of the corresponding author, and the number of citations in the Scopus database were obtained using the articles' digital object identifier when available, or the exact article title, journal, and year of publication.
    RESULTS: Of the 607 total poster and oral presentations from the 2014-2018 Annual Meetings of the AANS/CNS Joint CV Section, 46.29% (n = 281) have been published. Published articles received 3233 total citations for an average number of citations per article (± SD) of 10.89 ± 16.37. The average 5-year JCR IF of published studies was 4.64 ± 3.13. Additionally, 98.22% of published abstracts were in publication within 4 years from the time the abstract was presented. The most common peer-reviewed neurosurgical journals featuring these publications were the Journal of Neurosurgery, World Neurosurgery, the Journal of NeuroInterventional Surgery, Neurosurgery, and the Journal of Clinical Neuroscience.
    CONCLUSIONS: Nearly half of all poster and oral presentations at the annual meetings of the AANS/CNS Joint CV Section from 2014 to 2018 have been published in PubMed-indexed, peer-reviewed journals. The average number of citations per publication (10.89 ± 16.37) reflects the high quality of abstracts accepted for presentation. It is important to continuously assess the quality of research presented at national conferences to ensure that standards are being maintained for the advancement of clinical practice in a given area of medicine. Conference abstract publication rates in peer-reviewed journals represent a way in which research quality can be gauged, and the authors encourage others to conduct similar investigations in their subspecialty area of interest and/or practice.
    Keywords:  AANS/CNS Joint Cerebrovascular Section; SNIS; Society of NeuroInterventional Surgery; abstract; annual meeting; conference; podium presentation; poster presentation; publication rate
    DOI:  https://doi.org/10.3171/2023.8.JNS231549
  26. Br J Anaesth. 2023 Nov 02. pii: S0007-0912(23)00549-4. [Epub ahead of print]
      
    Keywords:  airway management; bibliometric analysis; direct laryngoscopy; tracheal intubation; videolaryngoscopy
    DOI:  https://doi.org/10.1016/j.bja.2023.09.029
  27. Environ Sci Pollut Res Int. 2023 Nov 07.
      The escalating issue of water pollution has become a worldwide issue that has captured the attention of numerous scientists. Molecularly imprinted polymers (MIPs) have emerged as adaptable materials with exceptional attributes, including easy synthesis, low cost, remarkable durability, long life, and accessibility. These attributes have motivated researchers to develop novel materials based on MIPs to tackle hazardous contaminants in environmental matrices. The purpose of this paper was to conduct a bibliometric analysis on MIPs' publications, in order to shed light on the developments and focus points of the field. The selected publications were obtained from Scopus database and subjected to a filtering process, resulting in 11,131 relevant publications. The analysis revealed that the leading publication source (journal) is Biosensors and Bioelectronics; the mostly employed keywords are solid-phase extraction, electrochemical sensor, and molecular recognition; and the top contributing countries are China, Iran, and the USA. The Latent Dirichlet Allocation (LDA) algorithm was used for extracting thematic axes from the textual content of the publications. The results of the LDA model showcase that the topic of synthesis and performance of MIPs for environmental applications can be considered as the most dominant topic with a share value of 72.71%. From the analysis, it can be concluded that MIPs are a cross-disciplinary research field.
    Keywords:  Bibliometric analysis; Molecular imprinting; Molecularly imprinted polymers; Scientometrics
    DOI:  https://doi.org/10.1007/s11356-023-30752-w
  28. Environ Sci Pollut Res Int. 2023 Nov 08.
      Microbial remediation technology has received much attention as a green, ecological, and inexpensive technology, and there is great potential for the application of microbial remediation technology for heavy metals (HMs) contaminated soil alone and in conjunction with other technologies in environmental remediation. To gain an in-depth understanding of the latest research progress, research hotspots, and development trends on microbial remediation of HMs-contaminated soil, and to objectively reflect the scientific contributions and impacts of relevant countries/regions, institutions, and individuals of this field, in this manuscript, ISI Web of Knowledge's Web of Science™ core collection database, data visualization, and analysis software Bibliometrix, VOSviewer, and HistCite Pro were used to collect and analyze the relevant literature from 2000 to 2022, and 1409 publications were subjected to scientometric analyses. It involved 327 journals, 5150 authors, 75 countries/regions, and 2740 keywords. The current progress and hotspots on microbial remediation of HMs-contaminated soil since the twenty-first century were analyzed in terms of the top 10 most productive countries (regions), high-yielding authors, source journals, important research institutions, and hotspots of research directions. Over the past 22 years, China, India, and the USA have been the countries with the most articles. The institution and author with the most publications are the Chinese Acad Sci and Zhu YG, respectively. Journal of Hazardous Materials is the most productive journal. The keywords showed 6 co-occurrence clusters. These findings revealed the research hotspots, knowledge gaps, and future exploration trends related to microbial remediation of HMs-contaminated soil.
    Keywords:  Heavy metal-contaminated soil; Microbial remediation; Scientometric analysis; Web of Science
    DOI:  https://doi.org/10.1007/s11356-023-30655-w
  29. J Environ Manage. 2023 Nov 07. pii: S0301-4797(23)02301-0. [Epub ahead of print]349 119513
      Arsenic-contamination of soil and water has always been a topic of considerable concern, and the potential of biochar for remediation of arsenic contamination has been widely recognized due to its advantages, including abundant sources, simple preparation, large surface area, significant pore size, and rich functional groups. To gain insights into the development trends in this field and provide suggestions for future research directions, scientometric analysis was conducted on articles sourced from the Web of Science core collection database by using the CiteSpace and VOSviewer software. In total, 637 bibliographic records, retrieved using the keywords "biochar" and "arsenic" were analyzed based on publication distribution over the years, contributing countries, keywords, authors, cited authors, publishing journals, and highly cited articles. Further, progress maps were generated from these data sets to assess the current research landscape. Results revealed a steady increase in annual publications since 2009, and China has the most publications. Notably, Daniel C. W. Tsang stood out as a representative author. The journal "Science of the Total Environment" published the most articles related to biochar and arsenic. "Adsorption" is the most frequently occurring keyword. The investigations of the impact and mechanism of biochar and modified biochar on inorganic arsenic removal from water and immobilization in soil have been identified as current research focal points. In order to realize the efficient and safe use of biochar, the future necessitates the implementation of advanced technology to conduct further comprehensive research. This study highlights the ongoing advancements in the research field on biochar and arsenic. Valuable insights are provided for future researchers and policymakers to guide their significant efforts toward addressing the issue of soil and water contamination caused by arsenic and exploring the potential of biochar for effective remediation strategies.
    Keywords:  Arsenic; Bibliometrics; Biochar
    DOI:  https://doi.org/10.1016/j.jenvman.2023.119513
  30. J Refract Surg. 2023 Nov;39(11): 784-790
      PURPOSE: To provide a comprehensive analysis of the most highly cited modern articles in refractive surgery, those published between 2010 and 2020, and compare these results to a list of the most highly cited articles in refractive surgery from all timepoints.METHODS: The Scopus database was searched for articles pertaining to refractive surgery using multiple search terms to identify the top 100 most cited articles in refractive surgery published between 2010 and 2020. Articles were reviewed for relevance and ranked based on total citations accrued.
    RESULTS: The 100 most cited modern articles in refractive surgery were identified. The article with the most citations by Sekundo et al has garnered nearly 600 citations to date. Almost all articles (88%) included in the top 100 had 200 or more citations. Intraocular lens (34 articles), keratorefractive lenticule extraction (ie, small incision lenticule extraction) (27 articles), and laser in situ keratomileusis (17 articles) were the predominant topics. Aarhus University in Denmark generated the most articles (5), whereas numerous articles originated from multiple countries, including the United States (16), United Kingdom (10), France (8), Spain (8), China (7), and Germany (7).
    CONCLUSIONS: This list provides a comprehensive assessment of the most cited modern articles in refractive surgery and demonstrates key focuses and trends in the field over the past decade. Intraocular lens and keratorefractive lenticule extraction were the primary topics. There was a broader representation of procedures, topics, authors, and country of origin as compared to prior work. [J Refract Surg. 2023;39(11):784-790.].
    DOI:  https://doi.org/10.3928/1081597X-20230925-01
  31. J Burn Care Res. 2023 Nov 02. pii: irad172. [Epub ahead of print]
      Inhalation injury is a common complication in burn patients and is also a factor that can affect the multiple prognoses of burn patients. Attention to inhalation injury began early globally, but few articles have systematically analyzed its development. We employed bibliometric methods to analyze articles on inhalation injury published in three medical databases. A total of 3,056 relevant articles on inhalation injury were included in our analysis and divided into three distinct periods based on Price's Law. Notably, a slowdown in publication growth was observed in period III. The majority of these articles were authored by a small group of individuals, with a significant proportion of them being American scholars. In fact, nearly half of the articles were published by American researchers. Applying Bradford's Law, we identified four major output sources in the field, namely Burns, Journal of Burn Care & Research, Journal of Trauma, and Critical Care Medicine. Recent research has focused on the clinical risks and outcomes associated with inhalation injury, while basic research in this area has been relatively neglected over the last decade. In conclusion, the growth of publications on inhalation injuries has largely followed standard scientific growth patterns, with a small number of countries and established research groups contributing the majority of articles. However, the recent slowdown in scientific output is a cause for concern, and the lack of emphasis on basic research and clinical trials in this field raises questions about the foundation for widespread clinical management of inhalation injuries.
    Keywords:  Bibliometrics; Burns; Price's Law; inhalation
    DOI:  https://doi.org/10.1093/jbcr/irad172
  32. Int J Surg. 2023 Nov 03.
      AIM: This paper aimed to explore the application of Three-dimensional (3D) printing in cardiovascular diseases, to reach an insight in this field and prospect the future trend.METHODS: The articles were selected from the Web of Science Core Collection database. Excel 2019, VOSviewer 1.6.16, and CiteSpace 6.1.R6 were used to analyze the information.
    RESULTS: A total of 467 papers of 3D printing in cardiovascular diseases were identified, and the first included literature appeared in 2000. A total of 692 institutions from 52 countries participated in the relevant research, while the United States of America contributed to 160 articles and were in a leading position. The most productive institution was Curtin University , and Zhonghua Sun who has posted the most articles (n=8) was also from there. The Frontiers in Cardiovascular Medicine published most papers (n=25). The Journal of Thoracic and Cardiovascular Surgery coveted the most citations (n=520). Related topics of frontiers will still focus on congenital heart disease, valvular heart disease, and left atrial appendage closure.
    CONCLUSIONS: We summarized the publication information of the application of 3D printing in cardiovascular diseases related literature from 2000 to 2023, including country and institution of origin, authors, and publication journal. This study can reflect the current hotspots and novel directions for the application of 3D printing in cardiovascular diseases.
    DOI:  https://doi.org/10.1097/JS9.0000000000000868
  33. Medicine (Baltimore). 2023 Nov 03. 102(44): e35872
      Kinesiophobia is an excessive, irrational, debilitating fear of physical movement and activity caused by a sense of vulnerability to pain or re-injury, which can have a direct impact on physical functioning and mental well-being of patients. This paper aims to provide reliable support for future in-depth research on kinesiophobia through scientometrics and historical review. Studies on kinesiophobia published from 2002 to 2022 were retrieved from the Web of Science Core Collection. CiteSpace and VOSviewer were used to conduct bibliometric analysis of the included studies and map knowledge domains. Keywords were manually clustered, and the results were analyzed and summarized in combination with a literature review. A total of 4157 original research articles and reviews were included. Research on kinesiophobia is developing steadily and has received more attention from scholars in recent years. There are regional differences in the distribution of research. Chronic pain is the focus of research in this field. A multidisciplinary model of pain neuroscience education combined with physical therapy based on cognitive-behavioral therapy and the introduction and development of virtual reality may be the frontier of research. There is a large space for the study of kinesiophobia. In the future, to improve regional academic exchanges and cooperation, more attention should be given to the clinical applicability and translation of scientific work, which will be conducive to improving the quality of life and physical and mental health outcomes of kinesiophobia patients.
    DOI:  https://doi.org/10.1097/MD.0000000000035872
  34. Account Res. 2023 Nov 09.
      Background China initiated the "Five No's for Publication" in December 2015 as a response to rising incidents of retraction.Objective Use the number of retracted publications and their original publication time as proxies to investigate the effect of the Five No's policy on academic misconduct.Methods We searched the Retraction Watch Database for research articles published by Chinese scholars from 1 March 2010 to 29 February 2020. The short- and long-term trends of the number of publications were presented by conducting an interrupted time series analysis in quarterly time units.Results Of 4,215 retracted papers with Chinese authors, 2,881 involving academic misconduct were identified. In the first quarter (12.01.2015-02.29.2016) after the implementation of the Five No's, an average reduction of 55.80 (p < 0.001) publications that involve academic misconduct was observed, although there was an increase in the trend of publications of 3.34 per quarter (p < 0.01) in the long run (12.01.2015-02.29.2020), relative to the pre-intervention period (03.01.2010-11.30.2015). The validity of these results was further supported by three different robustness checks.Conclusion China's government should strengthen enforcement, promote education, and improve the scientific evaluation system to consolidate the influence of the Five No's policy and foster a cleaner research environment.
    Keywords:  Academic misconduct; Interrupted time series analysis; Retraction watch; Scientific integrity; policy evaluation
    DOI:  https://doi.org/10.1080/08989621.2023.2279569
  35. JSES Rev Rep Tech. 2023 Nov;3(4): 499-505
      Background: Baseball and softball are popular sports with similar rates of injury, especially among pitchers. However, parity between the two sports is lacking, as baseball receives greater research attention than softball. The purpose of this study was to describe the discrepancy between baseball and softball in terms of quantity and quality of research. We hypothesized baseball literature would outnumber softball literature, be published in higher-impact journals, and be of higher quality.Methods: A systematic review was performed to identify original research articles related to baseball and softball from 1990 to 2020. Articles pertaining to pitching were identified via literature searches of PubMed, the Physiotherapy Evidence Database, the Cumulative Index to Nursing and Allied Health Literature, and the Cochrane Central Register of Controlled Trials and further screened by two independent reviewers. Age group studied, journal impact factor, type of research, and level of evidence were compared between pitching-related baseball and softball articles. Injury-related studies were also subanalyzed, and a meta-analysis was performed to assess rates of shoulder and elbow injuries between baseball and softball pitchers.
    Results: There were 813 baseball publications and 158 softball publications that met our inclusion criteria. More baseball articles were published per year than softball (5:1, P < .001). Baseball had 368 articles related to pitching, while softball had significantly fewer at 49, and there were more baseball pitching articles published per year than softball pitching articles (7.5:1, P < .001). Pitching-related baseball articles were published in journals with a higher mean impact factor than softball pitching articles (3.1 vs. 2.0, P = .049). There was no difference in methodological index for non-randomized studies criteria for rigorous reporting (P = .678), and among all groups, most articles were level III evidence. Baseball pitching articles included more clinical articles than softball pitching articles (63% vs. 43%, P = .004). Despite the fact that softball pitchers have an odds ratio of shoulder and elbow injury slightly higher than baseball (4.02 vs. 3.60), injury-related studies focused on baseball outnumbered softball studies 7 to 1.
    Conclusion: Softball is under-represented in the literature when compared to baseball with over 5 times fewer peer-reviewed research articles, despite having slightly higher shoulder and elbow injury rates than baseball. Pitching-related softball articles are nearly 8 times less frequent compared to baseball pitching articles and published in journals with a lower impact factor. Further research directed at softball is important to provide evidence-based injury prevention, practice guidelines, and treatment decisions.
    Keywords:  Bias; Elbow; Gender disparity; Inequality; Rotator cuff; Shoulder; Title IX
    DOI:  https://doi.org/10.1016/j.xrrt.2023.07.003
  36. World Neurosurg. 2023 Nov 04. pii: S1878-8750(23)01554-1. [Epub ahead of print]
      OBJECTIVE: This study investigates the scope, trends, and challenges of neurosurgical research in Nigeria since inception of the specialty in 1962.METHODS: A bibliometric review of the neurosurgical literature from Nigeria was done. Variables extracted included year and journal of publication, article topic, article type, research type, study design, article focus area, and limitations. Descriptive and quantitative analyses were performed for all variables. Trends of research publications were described in three periods - pioneering (1962-1981), recession (1982-2001), and resurgent (2002-2021).
    RESULTS: Of the 1023 included articles, 10.0% were published in the pioneering period, 9.2% in the recession period, and 80.8% in the resurgent period. Papers were predominantly published in World Neurosurgery (4.5%) and Nigerian Journal of Clinical Practice ( 4.0%). 79.9% of the 4618 authors were from Nigerian institutions. 86.3% of the articles covered clinical research and were mainly focused on service delivery and epidemiology (89.9%). The most prominent topics were traumatic brain injury (25.8%) and CNS malignancy (21.4%). Only 4.4% of the publications received funding, mostly from agencies in the US (31.7%). Barriers to neurosurgical research included lack of clinical databases (18.0%), increasing burden of disease (12.5%), and diagnostic challenges (12.4%).
    CONCLUSION: Neurosurgical research in Nigeria continues to grow due to increased training, workforce, and infrastructural improvements. Addressing the major challenges through establishment of research databases, development of evidence-based management guidelines, and increasing research training, funding and opportunities can increase research capacity in Nigeria.
    Keywords:  Bibliometric review; Challenges; Neurosurgical research; Nigeria; Scope; Trends
    DOI:  https://doi.org/10.1016/j.wneu.2023.10.147
  37. Pak J Med Sci. 2023 Nov-Dec;39(6):39(6): 1595-1600
      Background and Objective: Patient safety is a major concern in health care. Research is an important tool to minimize preventable errors. Research performance and trends evaluation need to be identified for future guidance. Our objective was to evaluate the research performance in Arab World countries related to patient safety so that real picture is available to all stake holders for future application.Methods: This was a descriptive exploratory study carried at King Abdulaziz University Jeddah, using Bibliometric analyses on Web of Science extracted data, exploring the research publications related to Patient Safety from the Arab World in last two decades (2001-2020). Digital resources were used. Data collected was further explored to see the trends.
    Results: Only 2% of total worldwide publications on Patient Safety were from Arab World. A positive trend, however, has emerged since 2015. Out of 5940 documents identified, only 383 had single authorship. Egypt and Saudi Arab were the major contributors. Other countries had less or even zero publications. Researchers are coordinating with others in Western countries to enhance the research productivity. Cairo University with 734 publications had most affiliations. Publications on safety culture and medication safety were frequent. Hospital Acquired Infections and error reporting had limited research.
    Conclusion: Researches on patient safety in the Arab World are not sufficient. Countries other than Egypt and Saudi Arabia also need to contribute more frequently. Critical problems, like Hospital Acquired Infections, should have regular research from all countries to assist those treating patients and those making health related policies.
    Keywords:  Arab World; Bibliometric analyses; Medical Research; Patient Safety
    DOI:  https://doi.org/10.12669/pjms.39.6.7514
  38. Philos Ethics Humanit Med. 2023 Nov 09. 18(1): 17
      BACKGROUND: Neuroscientific approaches have historically triggered changes in the conception of creativity and artistic experience, which can be revealed by noting the intersection of these fields of study in terms of variables such as global trends, methodologies, objects of study, or application of new technologies; however, these neuroscientific approaches are still often considered as disciplines detached from the arts and humanities. In this light, the question arises as to what evidence the history of neurotechnologies provides at the intersection of creativity and aesthetic experience.METHODS: We conducted a century-long bibliometric analysis of key parameters in multidisciplinary studies published in the Scopus database. Screening techniques based on the PRISMA method and advanced data analysis techniques were applied to 3612 documents metadata from the years 1922 to 2022. We made graphical representations of the results applying algorithmic and clusterization processes to keywords and authors relationships.
    RESULTS: From the analyses, we found a) a shift from a personality-focus quantitative analysis to a field-focus qualitative approach, considering topics such as art, perception, aesthetics and beauty; b) The locus of interest in fMRI-supported neuroanatomy has been shifting toward EEG technologies and models based on machine learning and deep learning in recent years; c) four main clusters were identified in the study approaches: humanistic, creative, neuroaesthetic and medical; d) the neuroaesthetics cluster is the most central and relevant, mediating between creativity and neuroscience; e) neuroaesthetics and neuroethics are two of the neologism that better characterizes the challenges that this convergence of studies will have in the next years.
    CONCLUSIONS: Through a longitudinal analysis, we evidenced the great influence that neuroscience is having on the thematic direction of the arts and humanities. The perspective presented shows how this field is being consolidated and helps to define it as a new opportunity of great potential for future researchers.
    Keywords:  Educational innovation; Higher Education; Humanities; Neuro-Arts; Neuroaesthetics; Neurosciences; R programming; Scopus
    DOI:  https://doi.org/10.1186/s13010-023-00147-3
  39. Neurosci Biobehav Rev. 2023 Nov 04. pii: S0149-7634(23)00427-X. [Epub ahead of print] 105458
      Gender equality or the lack thereof is a constantly recurring theme. Here, we sought to provide an overview of the status with respect to the participation and leadership of female doctors in clinical neuroscience analyzing different disciplines (neurosurgery, neurology and psychiatry). A total of 1910 articles published in six representative journals (07-12/2020) were reviewed. Of these, 1327 were original research papers, 145 invited publications and 303 letters/comments. Out of a total of 15,080 authors, 4365 (29%) were women. The percentage of female authors was found to differ significantly between the different specialties (19% in neurosurgery, 39% in neurology and 45% in psychiatry). Women were last authors in 9.5% of the papers in neurosurgery, 29% in neurology and 39% in psychiatry Based on these findings, it can be concluded that gender disparity in academic neuroscience is quite conspicuous. Our review seeks to address the reasons behind this phenomenon in the context of new publications as well as various cultural and historical underpinnings.
    Keywords:  academic neuroscience; gender disparity; neurology; neurosurgery; psychiatry
    DOI:  https://doi.org/10.1016/j.neubiorev.2023.105458
  40. Health Policy. 2023 Oct 30. pii: S0168-8510(23)00221-X. [Epub ahead of print]138 104936
      Well-being economies develop policies at the intersection of health and socio-economic inequalities. These policies are often informed by data-driven approaches, such as quality-of-life indicators. However, despite great efforts in measurement, it is known that the perspectives of underserved and unhealthy populations are not always fully captured. This raises the question to what extent well-being economy policies, informed by data alone, can adequately improve well-being for all. In this paper we investigate the potential of academia practice partnerships (AcPrac) in facilitating transfer and production of knowledge and skills between researchers and practitioners (including decision makers, governments, and communities) to create well-being policies informed by both data and people. We use bibliometric analysis to visualise the current state of knowledge on AcPrac. We find that 1) the health field has made the largest scientific contribution in this area, 2) cross-fertilization, which is at the heart of the well-being economy approach, is starting to take place between health and social sciences, and 3) concerns for equity are a shared value underlying transdisciplinary partnerships for well-being. Our findings contribute to understanding the role of AcPrac in advancing well-being economies and informing policy, but further research is needed to draw conclusions about its effectiveness.
    Keywords:  Academia practice partnerships; Bibliometric analysis; Equity; Health policy; Review; Well-being economy
    DOI:  https://doi.org/10.1016/j.healthpol.2023.104936
  41. Med Teach. 2023 Nov 10. 1-7
      PURPOSE: Medical education relies on clinical supervision for critical functions, including trainee assessment and ensuring patient safety. Yet, there is substantial variance in supervision, which has led to calls for a shared definition of the concept and guidelines to inform practice. AMEE Guide No. 27 provided these desired elements and is highly cited, suggesting that translation and utilization of the Guide's knowledge is suboptimal. This study investigates utilization by systematically characterizing citations to the Guide and by describing translation of its recommendations in relation to supervision.MATERIALS AND METHODS: Citations were identified using Web of Science, Scopus, and Google Scholar. The authors coded all citations and conducted a subanalysis of studies specific to supervision.
    RESULTS: 583 studies were identified; 268 met inclusion criteria for general analysis of which 167 studies were further analyzed. Most studies reiterated the Guide's characterization of effective supervision, but few demonstrate how these recommendations inform innovations in supervisory practice.
    CONCLUSION: Translation of the Guide's recommendations regarding clinical supervision appears limited. Future research should consider the extent of knowledge translation occurring in clinical supervision literature as well as AMEE Guides. Increased attention to knowledge translation in medical education may benefit the distribution of similar knowledge products.
    Keywords:  Educational and clinical supervision; knowledge translation; medical education
    DOI:  https://doi.org/10.1080/0142159X.2023.2257375
  42. J Psychoactive Drugs. 2023 Nov 06. 1-11
      Ibogaine is a natural psychoactive drug that has been investigated for its potential role in the treatment of substance use disorders since the mid-1960s. To evaluate the interest in ibogaine's use as a therapeutic agent, we performed a scientometric analysis covering the last three decades (1993-2002, 2003-2012, and 2013-2022). A complementary analysis was performed to select and describe published clinical trials and meta-analyses. A total of 1523 references were found. Linear growth of publications in the first and third decades were identified, and the average number of publications from 1993 to 2002 was lower than that in the other two decades. Researchers from five continents were identified. Globally, academic research centers in the United States and Canada were the most productive. Cocaine, tobacco, morphine, and alcohol prevailed as major keywords in the first two decades and opioids and psychedelics were included in the third decade. A few key authors were the most co-referenced. One preclinical meta-analysis and no meta-analysis in humans were found. Research trends for ibogaine are widespread, growing, and consonant with current attentiveness in drug abuse. Our findings support the pressing need for rigorous clinical research on ibogaine to evaluate its efficacy and safety.
    Keywords:  CiteSpace, psychedelics; Ibogaine; scientometrics; substance use disorders; vosviewer
    DOI:  https://doi.org/10.1080/02791072.2023.2276230
  43. Eur J Cancer. 2023 Oct 11. pii: S0959-8049(23)00680-9. [Epub ahead of print]195 113378
      Despite the strong evidence of prevention as a prime defence against the disease, the majority of cancer research investment continues to be made in basic science and clinical translational research. Little quantitative data is available to guide decisions on the choice of research priorities or the allocation of research resources. The primary aim of the mapping of the European cancer prevention research landscape presented in this paper is to provide the evidence-base to inform future investments in cancer research. Using bibliometric data to identify funders that are active in prevention research in Europe and in the world, we have identified that 14% of cancer research papers had a focus on prevention research and those were funded by 16% of all the European cancer research funders. An important finding of our study is the lack of research on primary prevention with primary prevention funders accounting for 25% of European cancer prevention funders, meaning that less than 4% of all European cancer research funders identified show an interest in primary prevention. An additional analysis revealed that 7% of European cancer prevention research papers are categorised as implementation projects, meaning that only 1% of all cancer research publications are implementation research in cancer prevention. This paper highlights that the narrow focus on biology and treatment in Europe needs to be widened to include such areas as primary prevention and secondary prevention and a larger concentration on implementation research. These data can help support a more policy-focused cancer research agenda for individual European governments and charitable and philanthropic organisations and stimulate joining efforts across Europe to create a more systematic and structured approach to cancer prevention.
    Keywords:  Cancer prevention research; Cancer research; European cancer research; Investments
    DOI:  https://doi.org/10.1016/j.ejca.2023.113378
  44. Int J Lab Hematol. 2023 Nov 05.
      Bone marrow adipose tissue (BMAT) has been histologically recognized for decades. In this study, we performed a bibliometric analysis to quantitatively analyze the clusters of keywords of BMAT and hematopoiesis to better understand BMAT and hematopoiesis. Starting with conclusive keywords, our results demonstrated that BMAds is distinct from extramedullary adipose tissues and maintains a routine but dynamic accumulation throughout an individual's life. Various pathophysiological factors take part in dysregulation of the adipose-osteogenic balance throughout life. Bone marrow adipocytes (BMAds) are also contradictorily involved in normal hematopoiesis, and positively participate in the occurrence and progression of hematologic malignancies, exerting a chemoprotective role in tumor treatment. Mechanically, metabolic reprogramming and abnormal secretory profile of BMAds and tumor cells play a critical role in the chemotherapy resistance. Overall, we hope that this work will provide new ideas for relevant future research on BMAds.
    Keywords:  bibliometric analysis; bone marrow adipocyte; hematological malignancy; hematopoiesis; metabolic reprogramming
    DOI:  https://doi.org/10.1111/ijlh.14198
  45. Chaos. 2023 Nov 01. pii: 111102. [Epub ahead of print]33(11):
      Scientific cooperation on an international level has been well studied in the literature. However, much less is known about this cooperation on an intercontinental level. In this paper, we address this issue by creating a collection of approximately 13.8×106 publications around the papers by one of the highly cited authors working in complex networks and their applications. The obtained rank-frequency distribution of the probability of sequences describing continents and the number of countries-with which authors of papers are affiliated-follows the power law with an exponent -1.9108(15). Such dependence is known in the literature as Zipf's law, and it has been originally observed in linguistics; later, it turned out that it is very commonly observed in various fields. The number of distinct "continent (number of countries)" sequences in a function of the number of analyzed papers grows according to power law with exponent 0.527(14); i.e., it follows Heap's law.
    DOI:  https://doi.org/10.1063/5.0166696
  46. Amino Acids. 2023 Nov 08.
      Bioactive peptides consist of small protein fragments, which are inactive in their original conformation, and they become active when released from these through enzymatic hydrolysis or fermentation processes. The bioactivity of such peptides has been extensively reported in the literature as contributors to organic homeostasis processes, as well as in immunomodulation, organism defense against oxidative processes, among others. In this study, reports of the activity of BPs isolated from milk with the potential glycemic control, antihypertensive activity, and inhibitors of uric acid formation were compiled. A systematic literature review and bibliometric analysis were conducted, using the PICO strategy for the research. The temporal analysis of publications revealed a growing interest in the investigation of bioactive peptides with potential antidiabetic, antihypertensive, and xanthine oxidase inhibitory activities, using dairy sources as products for their extraction. The literature analysis also revealed an increase in research involving non-bovine dairy products for bioactive peptide extraction. The collaboration network among authors exhibited weaknesses in scientific cooperation. Regarding the analysis of keywords, the usage of terms such as "bioactive peptides", "antioxidant", "antihypertensive", and "diabetes" was evident, constituting the main research clusters. Peptides with low molecular weight, typically < 10 kDa, of hydrophobic nature with aliphatic and aromatic chains, have significant implications in molecular interactions for the required activities. Although there is a growing interest in the industry regarding the utilization of bioactive peptides as potential drugs, there is a need to address gaps related to elucidating their interactions with cellular targets and their use in human therapy.
    Keywords:  Antidiabetic; Antihypertensive; Bioactive peptides; Milk; State of the art; Xanthine oxidase
    DOI:  https://doi.org/10.1007/s00726-023-03351-9
  47. Environ Sci Pollut Res Int. 2023 Nov 08.
      Plastic has been known as an artificial polymer whereas environmental microplastics become a global concern. Microplastics are reported to cause immunotoxicity in humans through gut deposition and entering the bloodstream. This study is a comprehensive indication of the recent research on microplastic toxicity in the gastrointestinal system. We performed bibliographic analysis using VOS viewer software and analyzed the data received on microplastics and their impact on gut health which has grown exponentially since 2016. Recent findings also support microplastic toxicity in combination with heavy metals. The smaller particle size and other factors enhanced the adsorption ability of environmental contamination such as heavy metals on microplastic which increased their bioaccumulation. Such toxic complexes of heavy metals and microplastics are a concern to natural ecosystems and environmental biologists. Few reports also demonstrated the biofilm formation on microplastic surfaces which might cause greater environmental as well as human health risks. Notably, terms of determining the microplastics in human tissues through several analytical techniques are still limited to some extent. Future research should be focused on the quantification of microplastics in human tissues, the combined effect of microplastics with other contaminants, and their effects on pre-existing diseases. This study boosts understanding of the potential impacts of microplastic and nanoplastic toxicity in the human gastrointestinal system.
    Keywords:  Bibliographic analysis; Heavy metals; Human health; Microplastic; Polystyrene; Toxicity
    DOI:  https://doi.org/10.1007/s11356-023-30801-4