bims-evares Biomed News
on Evaluation of research
Issue of 2021‒09‒05
37 papers selected by
Thomas Krichel
Open Library Society

  1. Ann Palliat Med. 2021 Aug 12. pii: apm-21-1836. [Epub ahead of print]
      BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease, the progression of which current drug therapy cannot reverse. This study analyzed current research hotspots and future research trends in IPF through bibliometric methods, with the aim of providing a reference for new therapeutic strategies.METHODS: Publications on IPF obtained from the Web of Science Core Collection database, The Literature Metrology Online Analysis Platform, and CiteSpace were used to analyze publication characteristics. VOSviewer was used to conduct keywords co-occurrence analysis and analyze research hotspots.
    RESULTS: A total of 7,016 publications related to IPF were identified from 2011 to 2020. The most contributions were from the USA and the five research institutions with the largest number of publications were all from that country. The American Journal of Respiratory and Critical Care Medicine was the most cited journal and had an incontrovertible academic impact with five of the top 10 high-cited references published in this journal. G Raghu was the academic authority in this domain in terms of both the number of publications and the most citations. By analyzing keywords, we identified three IPF research hotspot clusters, which are "clinical research", "pathogenesis research" and "diagnosis research" respectively.
    DISCUSSION: We evaluated all publications concerning IPF research in the past decade through bibliometric analysis. The current research hotspot in this field is drug therapy for the condition using nintedanib and pirfenidone. Future research will focus on conducting multi-center randomized controlled trials to explore and evaluate new therapeutic drugs for IPF. It is hoped that this study can provide information and data support for further research and the development of new therapeutic drugs.
    Keywords:  Bibliometric analysis; hotspots; idiopathic pulmonary fibrosis (IPF); nintedanib; pirfenidone
  2. Eur J Ophthalmol. 2021 Aug 28. 11206721211042556
      BACKGROUND: Limited research has examined differences between uncited papers and their most-cited counterparts. By comparing characteristics of each cohort, it is possible to better determine factors associated with increased citation count in the ophthalmology literature.METHODS: We initially identified all research articles published in six popular general ophthalmology journals (Ophthalmology, JAMA Ophthalmology, Investigative Ophthalmology and Visual Sciences, American Journal of Ophthalmology, British Journal of Ophthalmology, and Graefe's Archive for Clinical and Experimental Ophthalmology) between 2001 and 2011. Forty-nine articles were identified as having accrued zero citations as of March 2021 and were compared with an equivalent number of articles with the highest number of citations published in the same journals and time period. Significance (p < 0.05) for comparisons was determined using the Mann-Whitney U test and Fisher's exact test.
    RESULTS: Compared to the least-cited articles, the most-cited articles were significantly more likely to be clinical, multi-institutional, and multi-national in scope, report a statistically significant result, have a conflict of interest, state a funding source, and have higher sample sizes. These publications had significantly more words in the abstract and manuscript and more references. Overall, the first authors of the most-cited articles were significantly more likely to be female and report greater prior research productivity, as assessed by the relative citation ratio (RCR).
    CONCLUSION: Considering a small number of articles were uncited at least a decade after publication, it appears most research is useful for future investigations. However, there remain distinct differences between uncited articles and their most-cited equivalents in ophthalmology.
    Keywords:  Bibliometrics; citation count; literature analysis; ophthalmology; relative citation ratio
  3. Biomed Res Int. 2021 ;2021 1433684
      Background: The number of articles of clinical and basic research for osteonecrosis of the femoral head (ONFH) is increasing, yet, to our knowledge, there is still a lack of bibliometric analysis on ONFH articles. The purpose of this study was to identify the top 100 cited (T100) articles related to ONFH research and to analyze the characteristics and qualities of these articles.Methods: The T100 articles on ONFH were retrieved from the Web of Science database. The information about each article including citations, titles, authors, journals, countries, institutions, and keywords was recorded for bibliometric analysis.
    Results: The T100 articles related to ONFH were mainly published from 1991 to 2010 (n = 70) and were originated from 24 countries. The USA, China, and Japan were the most productive countries in this regard. The most prolific institution was the University of Pennsylvania from the USA with 6 publications and 742 citations. The most cited article was published in 1995 by Professor Steinberg ME. The five most frequently occurring keywords were "femoral head," "osteonecrosis," "core decompression," "total hip arthroplasty," and "follow up." The keywords like "bone tissue engineering" and "extracorporeal shock wave" have emerged in recent years.
    Conclusions: The USA, China, and Japan contributed greatly in terms of the T100 articles. The outcomes of core decompression and total hip arthroplasty gathered the most research interests. In recent years, bone tissue engineering and extracorporeal shock wave have become new trends. However, the mechanism of ONFH is still unclear.
  4. Optom Vis Sci. 2021 Aug 31.
      SIGNIFICANCE: Identification of the most impactful articles, authors, institutions, countries, and journals in myopia management provides a useful baseline reference for clinicians, researchers, and funding agencies in respect of this emerging field.This work aims to assemble publication metrics for myopia management to identify the most impactful articles, authors, institutions, countries, and journals in this emerging field of research. A search of the titles of articles was undertaken on the Scopus database to identify myopia management-related articles. The 25 most highly cited articles were determined from the total list of 1064 articles found. Rank-order lists by count were assembled for the top 25 in each of four categories: authors, institutions, countries, and journals. A subject-specific myopia management-related h-index (hMM-index) was derived for the entire field, in addition to each of the four categories, to serve as measures of impact in the field. Top 15 lists were generated for each category ranked by hMM-index and tabulated for consideration. An article by Christine Wildsoet and colleagues, describing choroidal and scleral mechanisms of compensation for spectacle lenses in chicks, has generated the most citations (412); Earl Smith is the most impactful author (hMM = 19); the University of Houston produces the most impactful articles (hMM = 31); the United States is the most highly ranked country (hMM = 60); and Optometry and Vision Science is the most impactful journal. Although still in its infancy, myopia management is a topic of emerging interest in the clinical and scientific ophthalmic literature. Impactful authors, institutions, countries, and journals are identified. Optometry is revealed as the leading profession in relation to the publication of myopia management-related articles.
  5. Clin Rheumatol. 2021 Sep 04.
      BACKGROUND: Takayasu arteritis (TAK) is a large vessel vasculitis affecting relatively younger population. Since literature on bibliometric analysis of TAK is scarce, we analyzed top-cited articles in TAK to address this knowledge gap.METHODS: We analyzed the top hundred cited articles in TAK on Web of Science and Scopus for time of publication, article type, country of origin, source journal, and authors. Furthermore, we conducted univariable- and multivariable-adjusted linear regression analyses to explore associations of rank of cited articles, mean number of annual citations, and total citations with traditional (journal impact factor, CiteScore) and alternative (PlumX) metrics.
    RESULTS: Concordance between databases was 76%. Most top-cited articles were from the USA, Japan, or the UK, and published in Annals of the Rheumatic Diseases, Arthritis and Rheumatism, and Circulation and Rheumatology (Oxford). Original articles comprised a majority of these top-cited articles. Articles describing criteria or disease management recommendations received the highest mean number of citations. Performing multivariable-adjusted linear regression analyses, years of publication associated with mean annual citations on Web of Science as well as total citations across databases (p < 0.01). The 2-year JIF significantly associated with mean annual citations on Web of Science (p = 0.047). On Scopus, the number of captures denoted under PlumX metrics consistently associated with citations (p < 0.001).
    CONCLUSION: Both traditional and alternative metrics associate with higher citations in TAK. Development of disease assessment and clinical practice guidelines and conduct and reporting of randomized controlled trials to guide TAK management are important research areas. The key points themselves are all right. Key Points • A majority of top-cited papers in TAK are original articles. • Both traditional and alternative metrics associate with number of citations for these papers. • Recommendations for disease assessment or clinical practice and clinical trials are important research agenda in TAK.
  6. Disaster Med Public Health Prep. 2021 Aug 31. 1-21
      OBJECTIVES: Both citations and Altmetrics are indexes of influence of a publication, potentially useful, but to what extent that the professional-academic citation and media-dominated Altmetrics are consistent with each other is a topic worthy of being investigated. The objective is to show their correlation.METHODS: DOI and citation information of COVID-19 researches were obtained from the Web of Science, its Altmetric indicators were collected from the Altmetrics. Correlation between the immediacy of citation and Altmetrics of COVID-19 research was studied by artificial neural networks.
    RESULTS: Pearson coefficients are 0.962, 0.254, 0.222, 0.239, 0.363, 0.218, 0.136, 0.134, and 0.505 (p<0.01) for dimensions citation, attention score, journal impact factor, news, blogs, Twitter, Facebook, video, and Mendeley correlated with the SCI citation, respectively. The citations from the Web of Science and that from the Altmetrics have deviance large enough in the current. Altmetric score isn't precise to describe the immediacy of citations of academic publication in COVID-19 research.
    CONCLUSIONS: The effects of news, blogs, Twitter, Facebook, video, and Mendeley on SCI citations are similar to that of the journal impact factor. This paper performs a pioneer study for investigating the role of academic topics across Altmetric sources on the dissemination of scholarly publications.
    Keywords:  COVID-19; Journal Impact Factor; Neural Networks; Scholarly Communication; Social Media
  7. Asian J Psychiatr. 2021 Aug 27. pii: S1876-2018(21)00273-2. [Epub ahead of print]65 102817
      The paper examines the global research output on suicidal behavior during the COVID-19 pandemic. The Scopus database was used to identify the publications on suicidal behavior during the COVID-19 pandemic from the beginning of the pandemic to up to 17th May 2021. The 686 publications emerging from 78 countries were found on the topic. These publications received 7970 citations, with an average of 11.62 citations per paper. About one-sixth (16.33%) of the total publications were funded, and these publications averaged 17.24 citations per paper. The publications from the top 10 most productive countries accounted for 92.71% of all publications. The highest number of publications emerged from United States, United Kingdom, and India. However, the relative citation index was highest for publications arising from France, Bangladesh, and Germany. The total number of organizations and authors involved in these publications were 286 and 290, respectively. The top 20 most productive organizations and authors contributed to 35.13% and 17.64% of publications and 79.15% and 58.61% global citations share, respectively. The maximum number of papers were published in the Asian Journal of Psychiatry, followed by Psychiatry Research and Lancet Psychiatry. This study suggests that suicidal behavior has received considerable attention during the ongoing COIVD-19 pandemic.
    Keywords:  COVID-19; bibliometrics; global; impact; publications; scientometrics; suicide
  8. Semergen. 2021 Aug 26. pii: S1138-3593(21)00222-7. [Epub ahead of print]
      OBJECTIVE: Analyze the thematic lines of the articles and reviews published between 2015 and 2019 in the journals indexed in the "Primary Health Care" category of the Journal Citation Reports.METHODS: Observational bibliometric study. The bibliographic records of the Web of Science were identified and the frequencies of appearance of the thematic descriptors and their co-occurrence in the documents included in the study were analyzed. In addition to the global analysis, the reviews, the most cited documents, those published in 2015, and those published in 2019 were analyzed separately. Descriptors were classified by thematic clusters using the Current Canadian Index scale and clinical publications were analyzed using the second edition of the International Classification of Primary Care.
    RESULTS: A total of 16,444 descriptors were identified in the 7,453 documents analyzed. The most frequent descriptors focus on: diagnosis, prevalence, management, risks, care practice and the figure of the health professional. In the most cited documents, terms with specific themes were used: depression, intervention, satisfaction, quality, therapy, research-based practice. In 2019, there were a greater number of publications focused on epidemiology, clinic, research and provision of services. From a clinical point of view, studies on psychological and mental health problems, nervous system, social problems, palliative care and cancer increased in 2019.
    CONCLUSIONS: The analysis carried out identifies the relevant thematic lines in primary care journals, highlighting the diagnosis and prevalence of diseases, the management of pathologies and their associated risks, as well as clinical practice and the figure of the health professional.
    Keywords:  Análisis bibliométrico; Análisis temático; Atención Primaria; Bibliometric analysis; JCR; Journal Citation Reports; Primary Health Care; Revistas científicas; Scientific journals; Thematic analysis
  9. Heliyon. 2021 Aug;7(8): e07778
      Industrial parks have been used to promote the economic development of countries. However, its rapid growth has generated environmental problems related to the depletion of natural resources and pollution. Consequently, the network analysis and the bibliometric analysis applied in this research generated qualitative and quantitative information from a systemic perspective on the thematic and community evolution of research on industrial parks (IP) performed to improve its negative environmental impact and reach sustainability. This study used the Web of Science (WoS) database from 1996 - 2019. The main trends and critical research points were identified in four periods of 6-year each. Social network analysis (SNA) was used to identify the intellectual structure main and the academic collaboration networks established among countries/territories, institutions, and authors. The most productive country in articles is currently China (882), however, when we consider the frequency of articles per million inhabitants, it ranks seventh. The WoS database grouped 63.6 ​% of the articles published in the subjects of "Environmental Sciences & Ecology", "Engineering", and "Science & Technology - Other Topics". Industrial Ecology (IE), Industrial Symbiosis (IS), and Circular Economy (CE) were the author keywords with the highest frequency, indicating that IP research has focused from these perspectives to promote the exchange of byproducts and to evaluate the performance and environmental impact of industrial areas through the use of methodologies such as carbon footprints, emergy analysis, and life cycle analysis (LCA). Finally, some themes were identified and proposed for future research based on analyzing research trends and hot spots from the literature review on industrial parks.
    Keywords:  Circular economy; Development sustainable; Industrial ecology; Industrial park; Social network analysis; Sustainability
  10. Front Oncol. 2021 ;11 683232
      Background: Bibliometric analysis is used to gain a systematic understanding of developments in the field of the influence of anesthesia on tumor prognosis and changes in research hot spots over the past 20 years.Methods: Relevant publications from the Web of Science Core Collection (WoSCC) were downloaded on May 5, 2021. Acquired data were then analyzed using the Online Analysis Platform of Literature Metrology ( and the CiteSpace software was used to analyze and predict trends and hot spots in this field.
    Results: 1,521 publications on the influence of anesthesia on tumor prognosis were identified and 1494 qualifying records were included in the final analysis. The leading country in this field was the United States of America (USA). The University of Texas MD Anderson Cancer Center (Houston, TX, USA) and Pennsylvania State University (State College, PA, USA) featured the highest number of publications among all institutions. Co-citation cluster labels revealed characteristics of ten main clusters: total intravenous anesthesia, opioid growth factor receptor, gastric cancer cell, opioid receptor, murine model, natural killer cell activity, health-related quality, glioma cell, opioid switching and mu-type opioid receptor. Keyword burst detection indicated that randomized controlled trials (RCTs), volatile anesthetics, and ropivacaine were the newly emerging research hot spots.
    Conclusions: This study compiled 1494 publications covering anesthesia and tumor prognosis research and showed that the direction of these studies is likely in transition from opioids and their receptors to other anesthetics, and from retrospective studies to prospective randomized controlled trials. It provides guidance for further research and clinical applications on choosing anesthetic methods and drugs.
    Keywords:  CiteSpace; anesthetic methods; bibliometric analysis; hot spots; tumor recurrence
  11. JB JS Open Access. 2021 Jul-Sep;6(3):pii: e21.00019. [Epub ahead of print]6(3):
      Inappropriate referencing of the existing literature has the potential to propagate false information. Quotation errors are defined as citations in which the referenced article fails to substantiate the authors' claims. The aim of this study was to determine the rate of quotation errors in high-impact general orthopaedic and sports medicine journals and to determine whether there are article or journal-related factors that are related to the rate of inaccuracies.Methods: A total of 250 citations from the 5 orthopaedic and sports medicine journals with the highest impact factors in 2019 (per Journal Citation Reports) were chosen using a random sequence generator. Reviewers rated the chosen citations by comparing the claims made by the authors with the data and conclusions of the referenced source to determine whether quotation errors were present. Logistic regression was utilized to assess for article- and journal-related factors related to the rate of quotation errors.
    Results: The overall quotation error rate was 13.6%. A total of 2.8% of the claims were completely unsubstantiated. The number of quotation errors did not significantly differ between the included journals. Single citations were significantly more likely than string citations to result in citations that could not be fully substantiated (χ2 = 4.57; odds ratio = 2.22; 95% confidence interval = 1.06 to 4.66; p = 0.03). No relationship was found between the rate of quotation errors and the total number of citations in the article, study type, or the graded level of evidence of the article.
    Conclusions: Quotation errors in high-impact factor orthopaedic and sports medicine journals are common. This is particularly important given the higher likelihood that studies in these journals are cited elsewhere, thus propagating the inaccuracies. Efforts from both authors and journals are needed to reduce quotation errors in the orthopaedic literature.
  12. PLoS One. 2021 ;16(9): e0256997
      INTRODUCTION: Degenerative Cervical Myelopathy (DCM) is a common and disabling condition, with a relatively modest research capacity. In order to accelerate knowledge discovery, the AO Spine RECODE-DCM project has recently established the top priorities for DCM research. Uptake of these priorities within the research community will require their effective dissemination, which can be supported by identifying key opinion leaders (KOLs). In this paper, we aim to identify KOLs using artificial intelligence. We produce and explore a DCM co-authorship network, to characterise researchers' impact within the research field.METHODS: Through a bibliometric analysis of 1674 scientific papers in the DCM field, a co-authorship network was created. For each author, statistics about their connections to the co-authorship network (and so the nature of their collaboration) were generated. Using these connectedness statistics, a neural network was used to predict H-Index for each author (as a proxy for research impact). The neural network was retrospectively validated on an unseen author set.
    RESULTS: DCM research is regionally clustered, with strong collaboration across some international borders (e.g., North America) but not others (e.g., Western Europe). In retrospective validation, the neural network achieves a correlation coefficient of 0.86 (p<0.0001) between the true and predicted H-Index of each author. Thus, author impact can be accurately predicted using only the nature of an author's collaborations.
    DISCUSSION: Analysis of the neural network shows that the nature of collaboration strongly impacts an author's research visibility, and therefore suitability as a KOL. This also suggests greater collaboration within the DCM field could help to improve both individual research visibility and global synergy.
  13. Rev Peru Med Exp Salud Publica. 2021 Apr-Jun;38(2):38(2): 224-231
      OBJECTIVE: To describe the Peruvian scientific output on COVID-19 up to January 31, 2021.MATERIALS AND METHODS: We carried out a bibliometric study using two databases (MEDLINE and SciELO). We included original or short original articles with at least one author with Peruvian institutional affiliation. Scientific output was described according to: institution, approval by a Research Ethics Committee, registration in the platforms established by regulations, scientific journals in which they were published, research funding, and Peruvian collaboration networks.
    RESULTS: A total of 106 articles were analyzed, only three (2.8%) were clinical trials. Of the top 10 institutions with the highest scientific output, only two did not belong to the education sector. A total of 53 (50.0%) articles had no information regarding ethical aspects or it was not explicitly stated whether or not it was approved by a Research Ethics Committee. Only 8 (7.7%) of 104 articles were registered in PRISA; 12 (11.3%) articles were published in Peruvian journals. Regarding funding, 71 (67.0%) investigations did not specify the source or they were self-financed. We found international collaboration in 70 publications (66.0%).
    CONCLUSIONS: The most productive Peruvian institutions are found in Lima. Half of the articles did not state ethical aspects in any part of the document. Almost all of the studies were not registered on the platforms established by regulations. In more than half of the articles the source of funding is not stated or they were self-financed.
  14. Environ Sci Pollut Res Int. 2021 Aug 31.
      In recent years, source appointment of soil heavy metal has attracted growing attention. However, few studies have attempted to make a comprehensive and systematical review on this topic. For this reason, a total of 1051 publications were retrieved from the Web of Science (WOS) database between 2000 and 2020. A scientometric analysis was carried out to reveal the characteristics of publications, research power, and research hotspots. CiteSpace was used to visualize and summarize the information about the development in this field. The results showed that (1) the number of publications in source appointment of soil heavy metal had increased rapidly; Environmental science and ecology and environmental sciences were top 2 most popular subject categories; (2) Research power was mainly distributed in Asia, Europe, and North America. China and Chinese Academy of Sciences were the most productive country and institution in terms of publications in this field. Biao Huang (China) was the most productive author. However, Hakanson L (Sweden) was the most influential author in terms of citation frequency; (3) Heavy metal, source identification, and contamination were the most frequent keywords. Keyword clustering analysis showed that the research hotspots mainly concentrated on air pollution, bioremediation, spatial distribution, soil, PCA, and so on; (4) Keyword bursts analysis showed that the research frontiers mainly focused on spatial analysis of soil heavy metal and exposure risk to human health.
    Keywords:  CiteSpace; Soil heavy metal; Source appointment; Web of Science (WoS)
  15. Front Pharmacol. 2021 ;12 725162
      Objective: A scientometric analysis to obtain knowledge mapping of Coptis revealed the current research situation, knowledge base and research hotspots in Coptis research. Methods: Coptis-related documents published from 1987 to 2020 were selected through the Web of Science Core Collection. CiteSpace, VOSviewer and Microsoft Excel were used to construct knowledge maps of the Coptis research field. Results: A total of 367 documents and their references were analyzed. These papers were primarily published in mainland China (214), followed by Japan (57) and South Korea (52), and they each formed respective cooperation networks. The document co-citation analysis suggested that the identification of Coptis Salisb. species, the production of alkaloids, and the mechanisms of action of these alkaloids formed the knowledge bases in this field. A keyword analysis further revealed that the research hotspots were primarily concentrated in three fields of research involving berberine, Coptis chinensis Franch, and Coptis japonica (Thunb) Makino. Oxidative stress, rat plasma (for the determination of plasma alkaloid contents), and Alzheimer's disease are recent research hotspots associated with Coptis. Conclusion: Coptis research was mainly distributed in three countries: China, Japan, and South Korea. Researchers were concerned with the identification of Coptis species, the production of Coptis alkaloids, and the efficacy and pharmacological mechanism of the constituent alkaloids. In addition, the anti-oxidative stress, pharmacokinetics, and Alzheimer's disease treatment of Coptis are new hotspots in this field. This study provides a reference for Coptis researchers.
    Keywords:  CiteSpace; Coptis; VOSviewer; berberine; scientometric
  16. J Public Health Res. 2021 Jun 16. 10(3):
      The advances in eHealth have dramatically changed the face of healthcare delivery around the world, with Sub-Saharan Africa being no exception. It is essential to identify the prominent, emerging researchers, successful areas of research within the field of health informatics (HI) and telemedicine (TM) to be duplicated where there is a need. This study gives a bibliometric overview of original research articles on medical informatics and telemedicine indexed in Scopus, PubMed, and Science Direct over the last 20 years in sub-Saharan Africa. Keywords related to health informatics and telemedicine were used to retrieve relevant literature. We specifically analyzed the evolution, standard metrics, domains of medical informatics (MI) and TM in sub-Saharan Africa (SSA) and Brazil, Russia, India, China, and South Africa (BRIC) nations. Our results identified mhealth as the main field of research in telemedicine that has seen significant growth in both BRIC and SSA nations and is poised to be the focus of research activity in the near future. Research production in mhealth and telemedicine showed a considerable increase from 1999-2018. The production was dominated by articles from South Africa in Africa and China from the BRIC nations. Most prolific authors have resources and are leaders of health informatics projects. The production came from 26 sub-Saharan African countries, denoting this field's devotion in different areas around sub-Sahara. Research in mhealth needs to be encouraged, mostly in the fight against infectious and non-infectious diseases in sub-Saharan Africa, where technology can improve health services and decrease disease burden.
  17. Crit Care Med. 2021 Aug 13.
      OBJECTIVES: Diverse perspectives improve the quality of scholarly initiatives. The demographic and professional diversity of scientists who contribute to critical care research and publications has not been described for the Canadian Critical Care Trials Group. Our objective was to describe the diversity of authors of publications from the Canadian Critical Care Trials Group.DESIGN: We conducted a quantitative content analysis of peer-reviewed articles published on behalf of the Canadian Critical Care Trials Group.
    SETTING: All peer-reviewed articles that were published on behalf of the Canadian Critical Care Trials Group between 1994 and October 2020.
    SUBJECTS: For each publication, we recorded the study design, the number of authors, and national or international collaboration. For the lead author, the senior author, and each coauthor, we recorded the following facets of diversity: gender, professional role, medical discipline, geographic location, academic stage, and visible minority status.
    MEASUREMENTS AND MAIN RESULTS: We identified 354 eligible publications; 74% (263/354) reported observational cohort studies, randomized trials, and surveys. Of 4,246 authors, 1,205 were unique individuals. The mean (SD) number of authors per publication was 12 (7.1). Of all 4,246 authors, 37% were women, and 13.7% were members of a visible minority group. Of all lead or senior authors, 40% and 34% respectively were women; 15% of lead and 10% of senior authors were members of a visible minority group. Three-quarters (73%) of publications listed authors from more than one profession, and more than half (54%) listed authors from more than one medical discipline. Nearly half of publications (45%) listed authors who were early career faculty, 33% listed authors who were trainees, and 67% listed authors who were from visible minority groups. Authors from different provinces and from different countries were listed in 67% and 40% of publications, respectively.
    CONCLUSIONS: Authors of Canadian Critical Care Trials Group publications are diverse with regard to demographic and professional characteristics.
  18. Am J Epidemiol. 2021 Sep 01. 190(9): 1710-1720
      The annual meeting of the Society for Epidemiologic Research (SER) is a major forum for sharing new research and promoting the career development of participants. Because of this, evaluating representation in key presentation formats is critical. For the 3,257 presentations identified at the 2015-2017 SER annual meetings, we evaluated presenter characteristics, including gender, affiliation, subject area, and h-index, and representation in 3 highlighted presentation formats: platform talks (n = 382), invited symposium talks (n = 273), and chairing a concurrent contributed session or symposium (n = 188). Data were abstracted from SER records, abstract booklets, and programs. Gender was assessed using GenderChecker software, and h-index was determined using the Scopus application programming interface. Log-binomial models were adjusted for participant characteristics and conference year. In adjusted models, women were less likely than men to present an invited symposium talk (relative risk = 0.60, 95% confidence interval: 0.45, 0.81) compared with all participants with accepted abstracts. Researchers from US public universities, US government institutions, and international institutions were less likely to present a symposium talk or to chair a concurrent contributed session or symposium than were researchers from US private institutions. The research areas that were most represented in platform talks were epidemiologic methods, social epidemiology, and cardiovascular epidemiology. Our findings suggest differences in representation by gender, affiliation, and subject area after accounting for h-index.
    Keywords:  bibliometric data; professional society; representation
  19. J Adv Nurs. 2021 Sep 01.
      AIMS: To examine the distributed characteristics and explore the research themes of Doctor of Nursing Practice (DNP) dissertations during the past two decades.DESIGN: A descriptive statistical and visualization bibliometric analysis was conducted.
    METHODS: Doctor of Nursing Practice dissertations submitted between January 2005 and June 2021 were collected from the ProQuest Dissertations and Theses database. A descriptive statistical analysis was conducted to calculate the distribution of the DNP dissertations by granting institution and the published year of publications. The VOSviewer 1.6.13 was used to explore the bibliometric networks and research priorities of the DNP dissertations.
    RESULTS: A total of 4989 DNP dissertations from 90 universities were included in this study, all from the United States. The number of DNP dissertations showed an upward trend, with steady growth from 2005 to 2014 and rapid growth after 2015. The DNP studies focused on five areas: health care management in clinical nursing, advanced practice in nursing education and health education, public health problems, mental health care for adolescents and nurses and the older people care and long-term care.
    CONCLUSION: Parallel to the numerical increase in DNP dissertations is a steady expansion in the range of research topics and scopes, which is aligned with specific specializations of the DNP. Many are interdisciplinary and employ techniques imported from the fields of public health, psychology and social sciences, resulting in nursing educators and practitioners continually broaden their subject perspectives.
    IMPACT: Knowing where, when and why DNP research trends developed will help nursing educators to further develop DNP education and optimize DNP programs in the future, such as paying more attention to the nursing practice. Moreover, this study will inspire DNP students and researchers to expand their subject perspectives and broaden the research scope to solve nursing practice problems based on interdisciplinary theories and methods.
    Keywords:  Doctor of Nursing Practice; bibliometric analysis; dissertation; nursing; nursing education
  20. Laryngoscope. 2021 Sep 04.
      OBJECTIVES/HYPOTHESIS: Despite increasing the numbers of women entering the field, underrepresentation of women in otolaryngology has been reported. In the subspecialty of facial plastic and reconstructive surgery (FPRS), female representation and academic leadership have not been formally characterized. Our study aims to identify female representation and academic leadership roles in FPRS.STUDY DESIGN: Cross sectional analysis.
    METHODS: Analysis was performed using the 2020 American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS) membership directory. Board-eligible and board-certified FPRS surgeons were included. Data regarding academic rank, leadership position, academic productivity, and years in practice were collected from publicly available departmental websites. Academic productivity was measured using h-index.
    RESULTS: Of 1,421 members queried in the 2020 AAFPRS membership directory, 13.0% were female and 86.9% were male. Most practitioners (87.0%) work in a private practice setting, but of the 13.0% of academic FPRS surgeons, 25.9% were female. Most female facial plastic surgeons in academic practice were Assistant Professors (72.9%), whereas ranks were evenly distributed among male FPRS surgeons. Three (4.3%) of 69 AAFPRS fellowship directors were women, and 1 (1.8%) of 56 present or past AAFPRS presidents was female. Female FPRS surgeons had fewer years in practice and lower h-indices compared with male surgeons.
    CONCLUSIONS: Female FPRS surgeons hold fewer academic leadership positions and have lower academic productivity in comparison to male FPRS surgeons. Future studies are needed to elucidate the etiology of these gender differences.
    LEVEL OF EVIDENCE: Cross-sectional analysis Laryngoscope, 2021.
    Keywords:  Women; facial plastics; gender equality; leadership; representation
  21. Heliyon. 2021 Aug;7(8): e07809
      Research on innovation and sustainability is prolific but fragmented. This study integrates the research on innovation in management and business and STEM fields for sustainability in a unified framework for the case of developing countries (i.e., the Global South). It presents and discusses the output, impact, and structure of such research based on a sample of 14,000 + articles and conference proceedings extracted from the bibliographic database Scopus. The findings reveal research output inflections after global announcements such as UN-Earth Summits. The study also reveals the indisputable leadership of China in overall output and research agenda-setting. Nonetheless, countries such as India, Mexico, and Nigeria are either more efficient or impactful. GS research published in highly reputable journals is still scarce but increasing modestly. Central topic clusters (e.g., knowledge management) remain peripheral to the global Sustainable Development Goals (SDGs) research landscape. Finally, academic-corporate collaboration is in its infancy and limited to particular economic sectors: energy, pharmaceuticals, and high-tech.
    Keywords:  Bibliographic coupling; Developing countries; Innovation; Management; STEM; Sustainability
  22. Elife. 2021 Sep 03. pii: e71712. [Epub ahead of print]10
      Previous reports have described worsening inequalities of National Institutes of Health (NIH) funding. We analyzed Research Project Grant data through the end of Fiscal Year 2020, confirming worsening inequalities beginning at the time of the NIH budget doubling (1998-2003), while finding that trends in recent years have reversed for both investigators and institutions, but only to a modest degree. We also find that career-stage trends have stabilized, with equivalent proportions of early-, mid-, and late-career investigators funded from 2017 to 2020. The fraction of women among funded PIs continues to increase, but they are still not at parity. Analyses of funding inequalities show that inequalities for investigators, and to a lesser degree for institutions, have consistently been greater within groups (i.e., within groups by career stage, gender, race, and degree) than between groups.
    Keywords:  computational biology; none; systems biology
  23. Yearb Med Inform. 2021 Aug;30(1): 219-225
      OBJECTIVES: Provide an overview of the emerging themes and notable papers which were published in 2020 in the field of Bioinformatics and Translational Informatics (BTI) for the International Medical Informatics Association Yearbook.METHODS: A team of 16 individuals scanned the literature from the past year. Using a scoring rubric, papers were evaluated on their novelty, importance, and objective quality. 1,224 Medical Subject Headings (MeSH) terms extracted from these papers were used to identify themes and research focuses. The authors then used the scoring results to select notable papers and trends presented in this manuscript.
    RESULTS: The search phase identified 263 potential papers and central themes of coronavirus disease 2019 (COVID-19), machine learning, and bioinformatics were examined in greater detail.
    CONCLUSIONS: When addressing a once in a centruy pandemic, scientists worldwide answered the call, with informaticians playing a critical role. Productivity and innovations reached new heights in both TBI and science, but significant research gaps remain.
  24. R Soc Open Sci. 2021 Aug;8(8): 210072
      Every year the National Institutes of Health allocates $10.7 billion (one-third of its funds) for clinical science research while the pharmaceutical companies spend $52.9 billion (90% of its annual budget). However, we know little about funder collaborations and the impact of collaboratively funded projects. As an initial effort towards this, we examine the co-funding network, where a funder represents a node and an edge signifies collaboration. Our core data include all papers that cite and receive citations by the Cochrane Database of Systemic Reviews, a prominent clinical review journal. We find that 65% of clinical papers have multiple funders and discover communities of funders that are formed by national boundaries and funding objectives. To quantify success in funding, we use a g-index metric that indicates efficiency of funders in supporting clinically relevant research. After controlling for authorship, we find that funders generally achieve higher success when collaborating than when solo-funding. We also find that as a funder, seeking multiple, direct connections with various disconnected funders may be more beneficial than being part of a densely interconnected network of co-funders. The results of this paper indicate that collaborations can potentially accelerate innovation, not only among authors but also funders.
    Keywords:  collaborative funding; population health; science of funding; science of science; science of success
  25. Schweiz Arch Tierheilkd. 2021 Sep;163(9): 553-563
      INTRODUCTION: Animal experimentation is commonly practiced in scientific research worldwide. However, there are no globally accepted standards for regulating the ethical boundaries and accepted practices for animal experimentation. Large differences exist between countries. A report suggested that some researchers, especially from countries with more stringent animal experimentation regulations, may be relocating experimental research to countries with less stringent regulations. We followed a systematic literature review approach to identity publications and determine whether there is an increasing trend in expatriation of non-human primate experimentation by researchers based in Switzerland. We used the Projects People Publications database, which contains projects funded by the Swiss National Science Foundation, to identify researchers conducting experiments using non-human primates. This list of names, together with terms referring to non-human primates were used to search the Web of Science. Publications without an author affiliated to a Swiss institution, no living or only with free non-human primates, and non-original research were excluded. For each publication, we recorded the place of experimentation, funding source, number of animals, species and the statement of ethical approval. We retained 120 publications, involving more than 2,429 non-human primates. Macaca mulatta and Macaca fascicularis were the most common species. We could not confirm an increasing trend in expatriation of non-human primate experimentation outside of Switzerland. Over time, publications appeared to report the ethical approval number more consistently. These results should be interpreted with caution because the sample included only studies that were: 1) published and 2) reported in the Web of Science. Consequently, studies with insignificant results may have been excluded because these studies are rarely published, and studies of poor quality may have been excluded because they are often published in lower quality journals, not indexed by the Web of Science.
    Keywords:  Animal experimentation; Expérimentation animale; Primaten; Schweiz; Suisse; Svizzera; Switzerland; Tierversuche; Trend; Verlegung; espatrio; expatriation; primates non humains; primati non umani; sperimentazione animale; tendance; tendenza; trend; ­non-human primates
  26. Neurosci Lett. 2021 Aug 31. pii: S0304-3940(21)00585-1. [Epub ahead of print] 136207
      Rehabilitation Engineering is the use of engineering principles applied to rehabilitation, disability, and independent living. Google Scholar is a searchable resource that allows people from around the world to create profiles of their interests and collaborations, and it provides a means to search the broad scientific and technical literature. Google Scholar was used to identify the 150 most cited people who listed Rehabilitation Engineering in their profile. Research impact, characteristics, and areas of research of the most cited rehabilitation engineers were examined. Furthermore, gender and geographical differences in research metrics of the highest citied rehabilitation engineers were investigated. Consumer priorities in rehabilitation engineering were identified using a voice of consumer (VoC) survey and recent literature based on VoC studies. Gaps between research publication and activities and consumer priorities were identified to recommend seven areas of research with high demand and opportunity for growth and innovation. Implications.
    Keywords:  Disparity; Google Scholar; Persons with Disabilities; Rehabilitation Engineering; Voice of Consumer
  27. AIDS Res Hum Retroviruses. 2021 Aug 31.
      BACKGROUND: The Centers for AIDS Research (CFAR) program was established by the National Institutes of Health in 1988 to catalyze and support high impact HIV research and to develop the next generation of HIV investigators at academic institutions throughout the United States.METHODS: In 2014, the Penn CFAR, the Johns Hopkins University CFAR and the District of Columbia CFAR developed a partnership - the Mid-Atlantic CFAR Consortium (MACC) - to promote cross-CFAR scientific collaboration, mentoring and communication and to address the regional HIV epidemic.
    RESULTS: Over the past six years, the creation of the MACC has resulted in a rich web of interconnectivity which has fostered scientific collaboration through working groups on the Black MSM and Latinx regional HIV epidemics, joint peer-reviewed publications and successful collaborative grant applications on topics ranging from HIV prevention in young MSM, transgender women, implementation science and clinical epidemiology; supported developmental activities through the MACC Scholars program, cross-CFAR mentoring, joint symposia, cross-CFAR seminar participation and keynote speakers; and promoted strategic communication through advisory committees, best practices consultations and the social and behavioral science research network.
    DISCUSSION: The MACC has been highly impactful by promoting HIV science through regional collaboration, supporting a diverse network of scholars across three cities and focusing on the epidemic in underrepresented and marginalized communities. Lessons learned from this consortium may have implications for scientific research centers beyond the field of HIV.
  28. J Imaging. 2020 Oct 16. pii: 110. [Epub ahead of print]6(10):
      Nowadays, deep learning methods are employed in a broad range of research fields. The analysis and recognition of historical documents, as we survey in this work, is not an exception. Our study analyzes the papers published in the last few years on this topic from different perspectives: we first provide a pragmatic definition of historical documents from the point of view of the research in the area, then we look at the various sub-tasks addressed in this research. Guided by these tasks, we go through the different input-output relations that are expected from the used deep learning approaches and therefore we accordingly describe the most used models. We also discuss research datasets published in the field and their applications. This analysis shows that the latest research is a leap forward since it is not the simple use of recently proposed algorithms to previous problems, but novel tasks and novel applications of state of the art methods are now considered. Rather than just providing a conclusive picture of the current research in the topic we lastly suggest some potential future trends that can represent a stimulus for innovative research directions.
    Keywords:  artificial neural networks; deep learning; document image analysis and recognition; historical documents
  29. J Evid Based Med. 2021 Aug 30.
      In the past years, network meta-analysis (NMA) has been widely used among clinicians, guideline makers, and health technology assessment agencies and has played an important role in clinical decision-making and guideline development. To inform further development of NMAs, we conducted a bibliometric analysis to assess the current status of published NMA methodological studies, summarized the methodological progress of seven types of NMAs, and discussed the current challenges of NMAs.
    Keywords:  bibliometric analysis; diagnostic test accuracy; individual participant data; methodological advances; network meta-analysis
  30. BMC Med Res Methodol. 2021 Aug 31. 21(1): 182
      BACKGROUND: Healthcare decisions are ideally based on clinical trial results, published in study registries, as journal articles or summarized in secondary research articles. In this research project, we investigated the impact of academically and commercially sponsored clinical trials on medical practice by measuring the proportion of trials published and cited by systematic reviews and clinical guidelines.METHODS: We examined 691 multicenter, randomized controlled trials that started in 2005 or later and were completed by the end of 2016. To determine whether sponsorship/funding and place of conduct influence a trial's impact, we created four sub-cohorts of investigator initiated trials (IITs) and industry sponsored trials (ISTs): 120 IITs and 171 ISTs with German contribution compared to 200 IITs and 200 ISTs without German contribution. We balanced the groups for study phase and place of conduct. German IITs were funded by the German Research Foundation (DFG), the Federal Ministry of Education and Research (BMBF), or by another non-commercial research organization. All other trials were drawn from the German Clinical Trials Register or We investigated, to what extent study characteristics were associated with publication and impact using multivariable logistic regressions.
    RESULTS: For 80% of the 691 trials, results were published as result articles in a medical journal and/or study registry, 52% were cited by a systematic review, and 26% reached impact in a clinical guideline. Drug trials and larger trials were associated with a higher probability to be published and to have an impact than non-drug trials and smaller trials. Results of IITs were more often published as a journal article while results of ISTs were more often published in study registries. International ISTs less often gained impact by inclusion in systematic reviews or guidelines than IITs.
    CONCLUSION: An encouraging high proportion of the clinical trials were published, and a considerable proportion gained impact on clinical practice. However, there is still room for improvement. For publishing study results, study registries have become an alternative or complement to journal articles, especially for ISTs. IITs funded by governmental bodies in Germany reached an impact that is comparable to international IITs and ISTs.
    Keywords:  Access to information; Clinical decision-making; Evidence-based medicine; Health impact assessment; Knowledge translation; Practice guidelines as topic; Publishing; Randomized controlled trials as topic; Registries; Systematic reviews as topic
  31. J Cardiothorac Vasc Anesth. 2021 Aug 08. pii: S1053-0770(21)00678-9. [Epub ahead of print]
  32. Yearb Med Inform. 2021 Aug;30(1): 233-238
      OBJECTIVES: To summarize key contributions to current research in the field of Clinical Research Informatics (CRI) and to select best papers published in 2020.METHOD: A bibliographic search using a combination of Medical Subject Headings (MeSH) descriptors and free-text terms on CRI was performed using PubMed, followed by a double-blind review in order to select a list of candidate best papers to be then peer-reviewed by external reviewers. After peer-review ranking, a consensus meeting between two section editors and the editorial team was organized to finally conclude on the selected four best papers.
    RESULTS: Among the 877 papers published in 2020 and returned by the search, there were four best papers selected. The first best paper describes a method for mining temporal sequences from clinical documents to infer disease trajectories and enhancing high-throughput phenotyping. The authors of the second best paper demonstrate that the generation of synthetic Electronic Health Record (EHR) data through Generative Adversarial Networks (GANs) could be substantially improved by more appropriate training and evaluation criteria. The third best paper offers an efficient advance on methods to detect adverse drug events by computer-assisting expert reviewers with annotated candidate mentions in clinical documents. The large-scale data quality assessment study reported by the fourth best paper has clinical research informatics implications, in terms of the trustworthiness of inferences made from analysing electronic health records.
    CONCLUSIONS: The most significant research efforts in the CRI field are currently focusing on data science with active research in the development and evaluation of Artificial Intelligence/Machine Learning (AI/ML) algorithms based on ever more intensive use of real-world data and especially EHR real or synthetic data. A major lesson that the coronavirus disease 2019 (COVID-19) pandemic has already taught the scientific CRI community is that timely international high-quality data-sharing and collaborative data analysis is absolutely vital to inform policy decisions.
  33. Ophthalmol Glaucoma. 2021 Aug 26. pii: S2589-4196(21)00189-7. [Epub ahead of print]
      PURPOSE: To describe trends in the glaucoma fellowship match results, glaucoma applicant characteristics, and applicant characteristics associated with matching.DESIGN: Retrospective study.
    METHODS: De-identified, individual applicant data provided by the San Francisco (SF) Match were used to describe glaucoma fellowship match trends and applicant characteristics between 2010 and 2017. Publicly available, conglomerate SF Match data were used to determine trends in the number of programs participating in the glaucoma fellowship match, as well as the number of positions offered and filled from 2014 to 2019. All trends analyses were performed using linear regression models on log-transformed response variables. Summary statistics for applicants who matched in glaucoma were compared to those who did not match using chi-squared tests for categorical variables and Wilcoxon-rank sum or Kruskal-Wallis tests for continuous variables. A multivariable logistic regression model was used to evaluate factors associated with matching in glaucoma fellowship.
    MAIN OUTCOME MEASURES: Fellowship match status (matched in glaucoma versus did not match in any ophthalmology subspecialty) RESULTS: From 2010 to 2019, the number of matched glaucoma fellowship applicants increased from 54 to 77 (mean 3.3% per year, p=0.001), and the proportion of applicants to any ophthalmology fellowship who matched in glaucoma increased from 13% to 15.5% (mean 3% per year, p=0.041). Compared with applicants who did not match in any specialty between 2010 and 2017, matched glaucoma applicants were more likely to have graduated from a top 10 residency program (10.7% vs. 4.5%, p<0.001), U.S. medical school (93.1% vs. 39.1%, p<0.001), or U.S. residency program (95.0% vs. 42.2%, p<0.001), and complete more interviews (9 vs. 1, p<0.001). After controlling for potential covariates, factors associated with increased odds of matching into glaucoma included graduating from a US residency program (OR: 9.91, 95% CI: [5.45,18.03]), applying to fewer programs (OR: 0.91, 95% CI: [0.88,0.93]), and completing a greater number of interviews (OR: 1.49, [1.39,1.60]). USMLE Step scores were not associated with matching in glaucoma.
    CONCLUSION: The number of applicants who matched into glaucoma fellowship increased from 2010 to 2019. Factors associated with matching into glaucoma were graduating from a U.S. residency program and completing more interviews.
    Keywords:  glaucoma fellowship; medical education; ophthalmology
  34. Sci Total Environ. 2021 Nov 01. pii: S0048-9697(21)02363-9. [Epub ahead of print]793 147292
    Keywords:  Bibliometric; Front page; Glyphosate; SCI-EXPANDED; Searching keywords; Toxicology
  35. Educ Inf Technol (Dordr). 2021 Aug 23. 1-26
      The unpredictable pandemic has drastically altered learning approaches, where online learning has been booming. Through VOSviewer, this study visualizes the network of top authors, organizations, sources, and countries that have been devoted to online learning. Through meta-analyses via Stata/MP 14.0, this study identifies nine variables that may exert a significant effect on online learning outcomes during this special pandemic time in various countries and areas. The findings may be generalizable to America, Asia, and Europe. Although relatively fewer publications in Africa have been included, the findings could provide a meaningful reference for African researchers and practitioners. Future research could include more publications from more diversified backgrounds. Online learning design could also keep pace with the development of information technologies.Supplementary Information: The online version contains supplementary material available at 10.1007/s10639-021-10720-y.
    Keywords:  Bibliographic review; Influencing factors; Meta-analysis; Online learning; Pandemic