bims-evares Biomed News
on Evaluation of research
Issue of 2021‒05‒02
forty-one papers selected by
Thomas Krichel
Open Library Society

  1. BMC Nephrol. 2021 Apr 29. 22(1): 158
      BACKGROUND: Diabetic kidney disease (DKD) is one of the most important complications of diabetic mellitus. It is essential for nephrologists to understand the evolution and development trends of DKD.METHODS: Based on the total cited numbers in the Web of Science Core Collection, which was searched through September 28th, 2020, we performed a bibliometric analysis of the top 100 most cited full-length original articles on the subject of DKD. The timespans, authors, contributions, subcategories, and topics of those 100 articles were analysed. In addition, the evolution of topics in DKD research was investigated.
    RESULTS: There were 23,968 items under the subject of DKD in the Web of Science Core Collection. The top 100 cited articles, published from 1999 to 2017, were cited 38,855 times in total. Researchers from the USA contributed the most publications. The number of articles included in 'Experimental studies (EG)', 'Clinical studies (CS)', 'Epidemiological studies (ES)', and 'Pathological and pathophysiological studies (PP)' were 65, 26, 7, and 2, respectively. Among the 15 topics, the most popular topic is the renin-angiotensin-aldosterone system (RAAS), occurring in 26 articles, including 6 of the top 10 most cited articles. The evolution of topics reveals that the role of RAAS inhibitor is a continuous hotspot, and sodium-glucose cotransporter 2 (SGLT-2) inhibitor and glucagon-like peptide 1 (GLP-1) agonist are two renoprotective agents which represent novel therapeutic methods in DKD. In addition, the 26 clinical studies among the top 100 most cited articles were highlighted, as they help guide clinical practice to better serve patients.
    CONCLUSIONS: This bibliometric analysis of the top 100 most cited articles revealed important studies, popular topics, and trends in DKD research to assist researchers in further understanding the subject.
    Keywords:  ACE2; Bibliometric analysis; DKD; RAAS; SGLT-2
  2. Knee Surg Relat Res. 2021 Apr 29. 33(1): 14
      PURPOSE: Arthroscopy is an established sub-speciality in orthopaedics. With advancing technology, instrumentation and implants, this sub-speciality has seen an explosion of knowledge and techniques since its inception. The indications for arthroscopic management are increasing and, hence, the number of publications on this topic. There has been no study looking into the bibliometrics of all publications within this speciality. The purpose of this study was to look into the trends of published articles on arthroscopy from PubMed and Scopus including studying their citation numbers.MATERIALS AND METHODS: We set out to look into the number of publications from the earliest up to 2019 and their trends and citation numbers in PubMed and Scopus. We also performed a VOS viewer analysis of MeSH terms and titles of publications to look at research trends over time.
    RESULTS: There were 41,149 articles published on PubMed since 1955 and 50,373 articles on Scopus since 1939. The total number of citations were 912,630 for 38,338 cited articles. With 2864 publications in 2019, there was a more than four-fold increase from the number published in the year 2000. The knee joint was the most frequently published joint with an increasing trend in hip arthroscopy. Cohort studies were the most common with 13,180 articles followed by Reviews with 5746 articles. The top 10 authors, universities and journals were listed along with citation numbers. We analysed the trends of publications for each joint and compared them. Yearly citations have progressively increased to reach a maximum of 45,407 in 2007. Arthroscopy was the most published and cited journal on this topic. The Journal of Bone and Joint Surgery (JBJS) (Am) had the most citations per article. The USA and Hospital for Special Surgery, New York were the most published country and university, respectively.
    CONCLUSIONS: There is a healthy growth of publications on the subject of arthroscopy with a steep increase in the number of publications and citations in recent years. VOS Viewer analysis showed an evolution of research and practice in the field of arthroscopy. Recommendations were made for databases and search engines to improve on the search and analysis of such studies in the future.
  3. Chiropr Man Therap. 2021 Apr 28. 29(1): 17
      OBJECTIVE: To determine publication trends, gaps, and predictors of citation of chiropractic case reports (CRs).METHODS: A bibliometric review was conducted by searching PubMed, Index to Chiropractic Literature (ICL), and Google Scholar to identify PubMed-indexed CRs, which were screened according to selection criteria. Case reports were categorized by International Classification of Disease (ICD-10) code, patient age, topic describing case management or adverse effects of care, focus being spinal or non-spinal, journal type, integrative authorship, title metrics, and citation metrics. Binary logistic regression was used to identify independent predictors of citations per year and total citations greater than the median values.
    RESULTS: The search identified 1176 chiropractic CRs meeting selection criteria. There was an increasing trend of CRs having a case management topic, non-spinal focus, non-chiropractic journal, neuromusculoskeletal-focus, diagnosis of vascular pathology, and a decreasing trend of adverse effect vascular pathology CRs. Independent predictors of greater total citations (or citation rate) included ICD-10 categories of perinatal conditions, infections, "case" in title, case management topic, and physical therapy, integrative, and dental journal type. Predictors of fewer citations included diseases of the blood, neoplasms, other findings not elsewhere classified, a title > 11 words, and multidisciplinary authorship. ICD-10 categories describing non-musculoskeletal diseases and special populations such as pediatrics, pregnancy, and perinatal conditions had few CRs.
    CONCLUSION: Chiropractic CRs are diversifying from spine-related topics. Chiropractors are encouraged to publish objective, structured CRs within defined research gaps. Published CRs can inform the design of future research studies with a higher level of clinical relevance and evidence.
    Keywords:  Bibliometrics; Case reports; Chiropractic; Information science; Literature review; Musculoskeletal diseases; Spine
  4. Antibiotics (Basel). 2021 Apr 12. pii: 423. [Epub ahead of print]10(4):
      Tuberculosis is one of the oldest known diseases and the leading communicable cause of deaths worldwide. Although several studies have been carried out on tuberculosis, no research has examined the publication trends in this area. Hence, this study aimed to fill the gap by conducting a bibliometric study in publications trends on tuberculosis and tuberculosis-related studies in Africa from 2010-2019 and explore the hotspots. Information in published documents on tuberculosis and its related studies from 2010 to 2019 were retrieved from the Web of Science (WoS) database. The bibliometric tool biblioshiny and Microsoft Excel 2016 were used to analyse the top leading journals, top cited documents, authors' country production, country collaboration networks, most relevant authors, authors' impacts, most relevant authors by corresponding author, most cited countries, university collaborations, most relevant affiliations, conceptual structural maps, title word co-occurrence networks, collaboration and significance of individual sources, university, country and keyword relations. A total of 3945 published documents were retrieved. The analyses showed that European Respiratory Journal was the leading journal in publications on tuberculosis studies with a total of 452 published articles, the WHO 2012 report was the most cited document with 2485 total citations while South Africa was the most productive country in tuberculosis publications as well as the leading country with the highest co-authorship collaboration. Analysis of top relevant authors revealed that Anonymous (133) and Dheda (44) were the two topmost relevant authors of tuberculosis publications, South Africa was the most relevant country by corresponding authors and the topmost cited country for tuberculosis publications. Furthermore, analysis of the university collaborations network showed that the University of Cape Town was the topmost university in Africa with the highest collaboration network, tuberculosis as a word had the highest co-occurrence network while the Three Field Plot diagram revealed the relations between universities, keywords and countries. This study provides a quantitative and qualitative analyses of the leading journals, most cited published articles, title word occurrences, and most relevant authors in published documents on tuberculosis and tuberculosis related studies from 2010-2019.
    Keywords:  Mycobacterium tuberculosis; bibliometric study; collaboration; infection
  5. Ann Palliat Med. 2021 Apr 15. pii: apm-20-2546. [Epub ahead of print]
      In the recent years, migraine has been widely studied by scholars from all over the world. This study aimed to use scientometric methods to identify research frontiers and development trends in the field of migraine research. We used the Web of Science (WoS) core collection database to collect articles and reviews related to migraine published from 2010 to 2019 on March 25, 2020. VOSviewer, CiteSpace, and Excel were used for the scientometric analysis. A total of 6,357 publications (including 5,203 articles and 1,154 reviews) were identified. The United States published the most publications (n=2,151, 33.84%). Albert Einstein College of Medicine contributed the most publications (n=220, 3.46%). Cephalalgia was found to be the core journal with the most publications (n=766, impact factor 2019 =4.868) as well as the most co-citations (n=35,535). Lipton RB authored the most publications (n=159, 2.50%), while Silberstein SD received the most co-citations (n=4,215). The critical topics were causes and pathophysiological mechanisms, epidemiological characteristics, diagnostic criteria, treatment and prevention drugs, and migraine-related genes. Through the use of scientometric methods, this article has mapped the knowledge landscape of migraine research over the past decade. By showing the overall status of the field, it provides a useful reference for future research.
    Keywords:  CiteSpace; Scientometrics; VOSviewer; Web of Science (WoS); migraine
  6. J Pain Res. 2021 ;14 1007-1025
      Background: Given the rapid growth of the global aging population, pain has become an unneglectable concern amongst the elderly. The quantity of scientific research outputs on pain in the elderly has increased over time, but only a small number of studies have used bibliometric methods to analyze scientific research in this field. This paper aimed to analyze scientific research on pain in the elderly published from 2000 to 2019 in a systematic manner using bibliometric methods.Methods: Articles on pain in the elderly published from 2000 to 2019 were retrieved from the Web of Science (WoS). Abstracts were coded on the basis of predetermined items (eg, type of article, topic, type of subjects, pain characteristics), and relevant information on the first author, citation scores, and article keywords were collected.
    Results: A total of 2105 articles were included in this study. Statistical analysis revealed that the publication of articles on pain in the elderly increased in frequency over time (P<0.001). Most of the publications were original articles. Amongst the countries identified, the United States published the largest number of papers on this topic. Pain characteristics (50.21%), pain intervention (35.68%), and pain assessment (9.69%) were the main topics of research on geriatric pain. Back pain (12.30%) appeared to be the most popular pain type described in the included papers.
    Conclusion: This work provides researchers with an in-depth understanding of pain in the elderly by evaluating relevant publications in the past two decades. Researchers in this field are warranted to explore future directions on geriatric pain such as the transition from acute pain to chronic pain and the underlying mechanisms of pain in the elderly.
    Keywords:  bibliometric analysis; elderly; pain
  7. Asian J Surg. 2021 Apr 21. pii: S1015-9584(21)00208-6. [Epub ahead of print]
      The aim of this study was to explore and analyze the main features of the top 100 most-cited original articles, systematic reviews (SRs)/meta-analyses (MAs) in the field of robotic surgery, through scientometric analysis. VOSviewer and Excel 2019 were employed to conduct this scientometric study. We found that the majority of original articles (72/100) were published during the 2000s, while the majority of the top 100 most-cited SRs/MAs (91/100) during the 2010s. The USA was the most dominant country (n = 78), Henry Ford Health System was the most productive institution (n = 10), and Menon M was the largest contributing first author (n = 5) of the top 100 most-cited original articles. The USA was the most dominant country (n = 33), University of Padua was the most productive institution (n = 9), and Ficarra V was the largest contributing first author (n = 4) of the top 100 most-cited SRs/MAs. The top 100 most-cited original articles in robotic surgery have focused on the feasibility, outcomes and learning curve of robotic surgery for various neoplasms and cancers. The top 100 most-cited SRs/MAs have focused on the differences between robotic surgery and other types of surgery, with respect to the learning curve, costs, outcomes and experience in treating neoplasms, cancer and other diseases. In the future, the formation of cross-institutional and cross-disciplinary cooperation teams should be promoted and corresponding regulations and standards for specific diseases should be developed to regulate and promote the development of robotic surgery.
    Keywords:  Meta-analyses; Original article; Robotic surgery; Scientometrics; Systematic review
  8. World Neurosurg. 2021 Apr 22. pii: S1878-8750(21)00597-0. [Epub ahead of print]
      BACKGROUND: The ongoing trend of societal evolution in contemporary civilization has allowed increased inclusion of heterogenous identity groups into fields, such as neurosurgery, where certain groups have traditionally been underrepresented. In regard to the field of neurosurgery, the increasing recognition of the disparities faced by women is illustrated by a growing body of academic literature.METHODS: We conducted a bibliometric analysis querying the PubMed, Web of Science (WoS), Scopus, and Embase databases for articles on women in neurosurgery using the MeSH terms "woman," "women," "gender," neurosurgery," neurological surgery," and "neurosurgeon". Articles were excluded if they do not concern societal impact of non-male population in the context of neurosurgery. Total citations, mean citations per year, publishing journal information, and author demographics were abstracted from included reports. Associations between abstracted continuous variables was evaluated using the Pearson correlation coefficient. Derived p-values of less than 0.05 were taken as significant.
    RESULTS: A total of 49 articles were included. Total numbers of citations per report were positively associated with mean citations per year (r=0.7289, p=0.0253) the latter of which was slightly negatively associated with the age of the report (r=-0.0413, p=0.0009). Age of publication year was found to be negatively correlated with the number of reports published per year (r=-0.648, p=0.0066). Total citations per reports were significantly correlated with increased numbers of citations during the last completed calendar year (2019: r=0.8956, p=0.0397).
    CONCLUSION: ecognition in societal evolutionary trends as evidenced by academic activity has shown increased focus on the explicit and intrinsic biases faced by women in neurosurgery. Recent years have seen significant increases in published reports concerning the subject as well as rising academic impact per a given report. This phenomenon is speculated to continue and understanding to broaden as societal perception continues to develop.
    Keywords:  Gender disparity; Neurosurgery; Women; bibliometric analysis
  9. Community Dent Oral Epidemiol. 2021 Apr 26.
      OBJECTIVE: This study assessed the features of the 100 most-cited papers on oral health-related quality of life (OHRQoL).METHODS: The 100 most-cited OHRQoL papers were collected from Web of Science, adopting a combined keyword search strategy. Google Scholar and Scopus databases were searched to compare citations. The following data were extracted from papers: title of the paper, number of citations, authorship, country, year of publication, title of the journal, study design, sample size, topic and OHRQoL instruments used. Graphical bibliometric networks were created using VOSviewer software.
    RESULTS: The number of citations of the top 100 most-cited OHRQoL papers ranged from 73 to 949. Fifty-six papers received at least 100 citations and two received more than 400 citations. Most papers were from Canada (23%) and had been published in Community Dentistry and Oral Epidemiology (37%). David Locker was the most-cited author (25 papers; 3,521 citations). The cross-sectional study design was the most common (68%). The impact of oral health conditions on OHRQoL (43%) was the most frequent topic, and the Oral Health Impact Profile (OHIP) was the most commonly used OHRQoL instrument (48%).
    CONCLUSIONS: This bibliometric analysis highlighted the characteristics of the 100 most-cited OHRQoL papers, demonstrating that this field is far from saturated. This list of the most-cited articles can provide a reference point to guide oral health research, education and services.
    Keywords:  bibliometrics; citations; oral health-related quality of life; scientometrics
  10. Neuroradiol J. 2021 Apr 29. 19714009211012358
      OBJECTIVES: The number of original scientific researches on intracranial aneurysms has risen over the last 30 years. Despite the rise in the number of articles, there is no up-to-date exhaustive bibliometric research in the literature. This study aimed to contribute to the literature via a bibliometric analysis of the original scientific researches on intracranial aneurysms published over the last 30 years.METHODS: The literature review was done using the Web of Science. All articles and its citations containing aneurysm keywords were analyzed in the "title" section of articles published in the research areas: Neurosciences Neurology during 1980-2019. Correlation analyses between the number of articles produced by the countries and their economic and development indicators of gross domestic product, and Human Development Index were analyzed using the Spearman correlation coefficient. Linear regression analysis was utilized to estimate the number of articles to be published in the future.
    RESULTS: There were a total of 21,673 publications on intracranial aneurysms. Of these publications, 13,371 (61.7%) were articles. The three countries that produced the most articles were the USA (4098), Japan (2668), and China (937). A statistically significant correlation was found between the development indicators of world countries and publication productivity (p<0.001). The three journals that produced the most publications were Neurosurgery, Journal of Neurosurgery, and American Journal of Neuroradiology. The most cited article was published in Journal of Neurosurgery.
    CONCLUSION: This bibliometric study provides a collection of data that will help design future research on intracranial aneurysms more efficiently and make innovations at greater speed.
    Keywords:  Aneurysms; bibliometrics; intracranial aneurysms; neuroscience
  11. Int Ophthalmol. 2021 Apr 29.
      PURPOSE: Altmetric analyses are a new way of assessing and sharing scientific knowledge. Traditional metrics and altmetric analyses highlight key publications. The primary objective of this study was to evaluate the social attention paid to highly cited articles related to glaucoma in the recent English literature and compare with traditional citation metrics.MATERIALS AND METHODS: "Glaucoma" was entered as a search term into Thomson Reuter's Web of Science database, and all articles related to the topic in the last decade were identified. The 50 highly cited articles (T50 list) were analyzed by topic, journal name, author name, year of the publication and Altmetric Attention Score (AAS). Descriptive statistics and Spearman correlation test were determined with the use of SPSS.
    RESULTS: According to bibliometric criteria, there were 31,370 eligible articles and the median (range) citation number was recorded as 181.5 (158.75-250.75). The T50 list was ranked with AASs between 176 and 0. The median AAS was 5 (2.75-10). The main subjects of the top 10 highly cited articles were mostly related to follow-up and prognostics about glaucoma (n = 3), while the main subjects of the top 10 articles with the highest AAS were related to genetics in glaucoma pathogenesis (n = 2), treatment modalities (n = 2) and pathophysiology with therapeutics of glaucoma disease (n = 2). AASs and citation number showed a positive moderate correlation (r = 0.403 p = 0.004), although AASs did not correlate with journal impact factor (r = 0.36 p = 0.01). No statistically significant correlation was found for ASSs and citation numbers with H-index of the journals on the T50 list.
    CONCLUSIONS: Bibliometric-based altmetric analyses offer important but different perspectives regarding article impact. This study provides valuable information about trending topics related to glaucoma research and its impact in both the academic literature and social media CLINICAL TRIAL REGISTRATION: With regard to the data characteristics of the manuscript, which is mainly retrospective and international, the clinical trial registration process is theoretically not applicable to this study.
    Keywords:  Altmetric Attention Score; Glaucoma; Social media; Traditional metrics; Trend topics
  12. Healthcare (Basel). 2021 Apr 09. pii: 441. [Epub ahead of print]9(4):
      The application of artificial intelligence (AI) to health has increased, including to COVID-19. This study aimed to provide a clear overview of COVID-19-related AI publication trends using longitudinal bibliometric analysis. A systematic literature search was conducted on the Web of Science for English language peer-reviewed articles related to AI application to COVID-19. A search strategy was developed to collect relevant articles and extracted bibliographic information (e.g., country, research area, sources, and author). VOSviewer (Leiden University) and Bibliometrix (R package) were used to visualize the co-occurrence networks of authors, sources, countries, institutions, global collaborations, citations, co-citations, and keywords. We included 729 research articles on the application of AI to COVID-19 published between 2020 and 2021. PLOS One (33/729, 4.52%), Chaos Solution Fractals (29/729, 3.97%), and Journal of Medical Internet Research (29/729, 3.97%) were the most common journals publishing these articles. The Republic of China (190/729, 26.06%), the USA (173/729, 23.73%), and India (92/729, 12.62%) were the most prolific countries of origin. The Huazhong University of Science and Technology, Wuhan University, and the Chinese Academy of Sciences were the most productive institutions. This is the first study to show a comprehensive picture of the global efforts to address COVID-19 using AI. The findings of this study also provide insights and research directions for academic researchers, policymakers, and healthcare practitioners who wish to collaborate in these domains in the future.
    Keywords:  COVID-19; artificial intelligence; bibliometric analysis; coronavirus; health; machine learning
  13. Agri. 2021 Apr;33(2): 53-63
      OBJECTIVES: Fibromyalgia syndrome is a global health problem. The aim of this study was to analyze the top 100 cited articles.METHODS: Web of Science database was scanned for the period between 1990 and 2020 using the search term, 'fibromyalgia,' and the 100 most cited articles were determined. For the bibliometric analysis, a record was made of the article title, year of publication, number of authors and names, number of citations, citation index, name of the journal in which it was published, impact factor, type of article, and source of funding. The altmetric attention score was recorded from the automatic software calculation.
    RESULTS: The total number of citations of the articles in the top 100 list varied between 203 and 6254. The majority of articles were published in arthritis and rheumatism (n=24) and pain (n=15) journals. The country producing the most articles was the US and the most cited author was Russel IJ. Case-controlled studies constituted the largest part of the top 100 (n=36). When the number of citations was examined, studies evaluating classification criteria, diagnostic criteria, and epidemiologic study were at the forefront. In terms of altmetric attention score, treatment studies, especially exercise, were in the first orders.
    CONCLUSION: This study presents a view on the subject of the level of interest shown by the scientific world and on social platforms to the most cited articles on the subject of fibromyalgia. There is a need for further studies which would use more wide-scale databases and offer interactions between countries.
  14. J Hypertens. 2021 Apr 28.
      OBJECTIVE: The area of pediatric hypertension (HTN) research has seen substantial progress over the last two decades, but no bibliometric analysis has yet been undertaken to describe these advances. This study aims to describe the published research examining HTN in children and adolescents from 2000 to 2018.METHODS: Articles were retrieved using PubMed and the Web of Science. Analyses were performed to quantify the evolution of scientific output, identifying the leading journals, authors, and countries as well as the existing collaboration networks. Likewise, we identified the most cited articles, describing their document type, main topic focus, and the age of the patients studied.
    RESULTS: In total, we identified 8317 articles in the Web of Science. The annual number of publications doubled over the study period. Articles were published in 1415 journals, mainly in the categories of Peripheral & Vascular Diseases and Pediatrics. The USA dominated scientific production in the field. Regarding researcher productivity, the top 202 authors participated in 20% of the articles, and there were 47 stable research clusters, with the largest component made up of 17 authors. Altogether, there were 145 most cited articles, with an irregular annual distribution; about half focus on HTN itself, while the rest study associated disorders and conditions.
    CONCLUSION: This is the first study to analyze scientific output on HTN in children and adolescents. The snapshot that emerges is of a research area that is growing but is still in a relatively early phase of development.
  15. Materials (Basel). 2021 Apr 23. pii: 2170. [Epub ahead of print]14(9):
      Road recycling technology is gradually becoming a research focus in road construction due to natural resource shortages. It is therefore necessary to carry out deep and extensive analysis of the huge amount of publications in the research area of recycling technology in road construction. Based on three databases (Web of Science, Compendex and Scopus) and VOSviewer visualization software, this study conducts a bibliometric analysis of the literature in the field of recycled construction materials in pavement engineering. The global research publications were reviewed to quantitatively identify the literature characteristics. A number of publications, document types, research areas and keywords were used to achieve the general statistics of this reviewed literature. H-index, publication number and citations per publication were used to evaluate the academic contributions by country, institution and journal. The results show that the most productive country and institution for publications are the USA and Chang'an University from China, respectively, followed by China and Wuhan University of Technology. In recent years, researchers have generally paid attention to two main approaches: the application of rubber modified asphalt and the performance enhancement of recycled pavement.
    Keywords:  asphalt pavement; bibliometric analysis; pavement engineering; recycled materials; road recycling
  16. Environ Sci Pollut Res Int. 2021 Apr 28.
      Fine particulate matter (PM2.5) is one of the major air pollutants. A large number of epidemiological and experimental studies have shown that PM2.5 pollution can cause adverse health consequences, which has attracted more public attention. In order to have a deeper and more structured understanding of the research progress and frontiers on the impact of PM2.5 on health, in this study, we used the bibliometrics software CiteSpace to analyze the relevant literature in this field. The results show that since 2000, the relevant literature has increased steadily, especially in the last 5 years, and the number of publications in China has increased rapidly. The United States has the most publications. The Chinese Academy of Sciences and Professor Joel Schwartz are the most published institution and author, respectively, and many articles have been published in the journal of Environmental Health Perspectives. Over time, studies on the health effects of PM2.5 have gradually deepened. In addition to a more comprehensive study of its harmful effects, the related molecular mechanisms have also been further explored. We believe that countries and regions should strengthen cooperation and jointly solve the harm caused by PM2.5 through the integration of multiple disciplines and fields. In addition, the adverse health consequences and its related mechanisms caused by exposure to ultrafine particle, different chemical components of PM2.5, as well as the intervention of the health effects caused by PM2.5 need to be further studied.
    Keywords:  Bibliometric; CiteSpace; Health effect; PM2.5; Research progress; Web of Science
  17. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2021 Apr 25. 38(2): 317-325
      To explore the focus and trends in real-world studies in Chinese through knowledge mapping method, databases CNKI, VIP, Wanfang and Sinomed were retrieved, with 1 757 relevant articles published before September 30rd, 2020 finally included, whose bibliographical records were imported into NoteExpress to avoid duplication and check relativity. VOSviewer, a bibliometric analysis tool, was used to analyze their development. It was found that real-world studies have mainly taken shape after 2010, in which traditional Chinese medicine research plays an important role. China Journal of Chinese Material Medica was the leading journal with 120 papers, the China Academy of Chinese Medical Sciences the most contribution institution with 338 papers, and Xie Yanming from the institution the most contribution author with 250 papers. This study helps clinicians and researchers in better understanding the evolution of real-world research over more than two decades in China.
    Keywords:  bibliometric analysis; knowledge map; real-world research
  18. Dement Neuropsychol. 2021 Jan-Mar;15(1):15(1): 28-40
      Many studies have found that non-pharmacological interventions, such as cognitive stimulation (CS), can benefit people with dementia (PWD) or with mild cognitive impairment (MCI). The use of the computerized cognitive stimulation (CCS) had proven to be an ally to those who want to detect and mitigate this disease.Objective: The purpose of this paper was to analyze the scientific production in CCS in PWD or with MCI in journals indexed in Clarivate Analytics' Web of Science and Elsevier's Scopus since 2000.
    Methods: Data collected from Web of Science and Scopus during 2000-2019.
    Results: The data show that dementia research is exponentially developing following the evolution of widespread use of computer science. As such, this article was of enormous importance doing a bibliometric analysis of what has been done in the area since the beginning of this century. The search terms identified 61 papers related to the use of computers applied to CS in PWD or MCI, and the International Journal of Geriatric Psychiatry and Journal of Alzheimer's Disease had the largest number of publications. The most cited article was the Faucounau et colleagues. Major research' countries are United Kingdom, Spain and United States.
    Conclusions: The findings in these papers were analysed to find recommendations for future work in this area. The CCS has been increasingly used as an intervention tool for PWD or MCI, and there still seems to be a possibility for evolution in good quality publications.
    Keywords:  bibliometrics; cognition; computers; data analysis; dementia
  19. Implement Sci. 2021 Apr 26. 16(1): 47
      INTRODUCTION: Moving evidence-based practices into the hands of practitioners requires the synthesis and translation of research literature. However, the growing pace of scientific publications across disciplines makes it increasingly difficult to stay abreast of research literature. Natural language processing (NLP) methods are emerging as a valuable strategy for conducting content analyses of academic literature. We sought to apply NLP to identify publication trends in the journal Implementation Science, including key topic clusters and the distribution of topics over time. A parallel study objective was to demonstrate how NLP can be used in research synthesis.METHODS: We examined 1711 Implementation Science abstracts published from February 22, 2006, to October 1, 2020. We retrieved the study data using PubMed's Application Programming Interface (API) to assemble a database. Following standard preprocessing steps, we use topic modeling with Latent Dirichlet allocation (LDA) to cluster the abstracts following a minimization algorithm.
    RESULTS: We examined 30 topics and computed topic model statistics of quality. Analyses revealed that published articles largely reflect (i) characteristics of research, or (ii) domains of practice. Emergent topic clusters encompassed key terms both salient and common to implementation science. HIV and stroke represent the most commonly published clinical areas. Systematic reviews have grown in topic prominence and coherence, whereas articles pertaining to knowledge translation (KT) have dropped in prominence since 2013. Articles on HIV and implementation effectiveness have increased in topic exclusivity over time.
    DISCUSSION: We demonstrated how NLP can be used as a synthesis and translation method to identify trends and topics across a large number of (over 1700) articles. With applicability to a variety of research domains, NLP is a promising approach to accelerate the dissemination and uptake of research literature. For future research in implementation science, we encourage the inclusion of more equity-focused studies to expand the impact of implementation science on disadvantaged communities.
    Keywords:  Bibliometric study; Implementation science; Natural language processing; Synthesis and translation; Systematic review
  20. Indian J Ophthalmol. 2021 May;69(5): 1234-1240
      Purpose: Coronavirus disease pandemic has impacted global healthcare tremendously and ophthalmology is one of the high-hit specialties. An increasing number of research items are upcoming with COVID-19-related research in ophthalmology and this report aims at performing a scientometric analysis of all the available research pertaining to COVID-19 and ophthalmology.Methods: A Web of Science ( query TS = ("novel coronavirus 2019" OR "coronavirus 2019" OR "COVID 2019" OR "COVID 19" OR "nCOV" OR "SARS-CoV-2" OR "COVID-19") AND WC = ("Ophthalmology") was deployed on February 22, 2021, to retrieve all research items on the topics of interest. R software (v4.0.1) with Bibliometrix library was deployed to visualize metrics to quantify geographical distribution, source metrics, author metrics, document metrics, and keyword metrics.
    Results: A total of 616 research items appeared in our search results that were drafted by 2398 authors and published in 63 sources. India, USA, UK, and China had the greatest number of research items among others. Indian Journal of Ophthalmology, Eye, and Graefe's Archive for Clinical and Experimental Ophthalmology were sources with greatest number of research items. Documents per author were 0.257 and authors per document were 3.89. The collaboration index was noted to be 4.28.
    Conclusion: Our scientometric analysis presents descriptive quantitative metrics for COVID-related research in the field of ophthalmology and provides evidence for the increased global collaboration that global researchers have fostered to fight this pandemic.
    Keywords:  Bibliometric analysis; COVID-19 and ophthalmology; COVID-19 research trends; coronavirus and eye; coronavirus disease 2019; pandemic and ophthalmology research
  21. Int J Environ Res Public Health. 2021 Apr 16. pii: 4234. [Epub ahead of print]18(8):
      Drowning is public health issue requiring global, national and community responses. The multisectoral nature of drowning prevention reinforces the need for multidisciplinary research, which can play a key role in identifying patterns, factors and interventions and contributes to evidence-informed prevention. This study presents a biometric analysis of drowning research published in 1995-2020 and identifies temporal trends in research themes, journals, countries and authorship to assist in the planning of future research. This study identified 935 studies, representing authors from 80 countries. Publications grew 103-fold, and 41.2% (n = 385) were published since 2014. The top 20 journals are all injury prevention, public health, or medical journals. The top 5 accounted for 24.5% (n = 229) of total publications (TP). Research from the United States (TP = 313, 25.0%) and Australia (TP = 192, 15.3%) dominates the field. Growth is highest in low-middle-income countries (LMICs) including China (TP = 54, 4.3%, 32-fold), India (TP = 30, 2.4%, 17-fold) and Bangladesh (TP = 47, 3.7%, 7-fold). The study identifies significant growth in epidemiologic studies reporting burden and risk factors. Research in LMICs is increasing but lags relative to the burden. The role of multilateral and nongovernment organisations in evidence generation is evident and needs investigation, as do gaps in evidence for interventions and partnerships to progress the drowning prevention field.
    Keywords:  bibliometric analysis; drowning; drowning prevention; injury; publication trends
  22. Heliyon. 2021 Apr;7(4): e06726
      This paper analyzes the scientific map of technostress and the scientific production on this topic between 1982 and 2017, highlighting its structure, evolution, and trends in this field. A literature review based on bibliometric analysis of 246 records indexed in Scopus database was conducted. These publications were analyzed according to bibliometric indicators and through science maps with SciMAT. Co-occurrence of terms by grouping techniques was implemented. In addition, elaboration of maps of science and performance analysis for periods was executed. The main contribution of this work is to provide the first scientific map of technostress and a detailed understanding of the scientific production that predicts the directions of future research. The bibliometric analyses permit an overview of the growth, extent and distribution of the scientific literature related to the technostress and the study of the scientific production of an institution, country, author or research group.
    Keywords:  Bibliometric analysis; Bibliometric indicators; SciMat; Science mapping; Technostress
  23. Brain Sci. 2021 Apr 27. pii: 548. [Epub ahead of print]11(5):
      Neuromarketing, consumer neuroscience and neuroaesthetics are a broad research area of neuroscience with an extensive background in scientific publications. Thus, the present study aims to identify the highly cited papers (HCPs) in this research field, to deliver a summary of the academic work produced during the last decade in this area, and to show patterns, features, and trends that define the past, present, and future of this specific area of knowledge. The HCPs show a perspective of those documents that, historically, have attracted great interest from a research community and that could be considered as the basis of the research field. In this study, we retrieved 907 documents and analyzed, through H-Classics methodology, 50 HCPs identified in the Web of Science (WoS) during the period 2010-2019. The H-Classic approach offers an objective method to identify core knowledge in neuroscience disciplines such as neuromarketing, consumer neuroscience, and neuroaesthetics. To accomplish this study, we used Bibliometrix R Package and SciMAT software. This analysis provides results that give us a useful insight into the development of this field of research, revealing those scientific actors who have made the greatest contribution to its development: authors, institutions, sources, countries as well as documents and references.
    Keywords:  Bibliometrix; H-index; SciMAT; consumer behaviour; consumer neuroscience; consumer psychology; highly cited papers (HCPs); science mapping analysis; scientometrics
  24. Soc Sci Med. 2021 Apr 19. pii: S0277-9536(21)00282-3. [Epub ahead of print]278 113950
      This study compares the trajectories of recent scientific/intellectual movements (SIMs) in biomedicine: evidence-based medicine, translational medicine, precision medicine, personalized medicine, stratified medicine, and genomic medicine. Drawing on bibliometric analysis of these six SIMs, this study identifies three patterns: field integration, niche creation, and disruptive insurgence. Field integration SIMs such as evidence-based medicine and translational medicine are characterized by centrality of key concept papers of the SIM in co-citation networks and dense institutional and country collaboration networks, signaling the resonance of the SIM to the broader biomedical community. In contrast, niche creation SIMs such as stratified medicine and genomic medicine are characterized by lower levels of annual scientific production, the lack centrality or connectivity of key concept papers in co-citation networks, and less density in collaboration networks. Disruptive insurgence SIMs such as precision medicine and personalized medicine are characterized by a high level of annual scientific production, driven by a smaller core of institutions and countries. This is likely a transitional stage as field disrupting SIMs can either become integrated with the broader field or become influential in niches. Proponents of the current push for precision medicine should ensure that a wide range of institutions and specialties be included while being mindful of the dominance of cancer and genomic approaches to health and medicine.
    Keywords:  Biomedicine; Evidence-based medicine; Genomic medicine; Personalized medicine; Precision medicine; Scientific/intellectual movements; Stratified medicine; Translational medicine
  25. Turk Arch Otorhinolaryngol. 2021 Mar;59(1): 20-25
      Objective: To analyze the change over the 25 years period in the number of publications on allergic rhinitis from Turkey, and to compare the data of the four major relevant specialties.Methods: A search was conducted over 25-years between1994 and 2019 using the keywords "allergic rhinitis" and "Turkey" in PubMed®, and "allerji", "alerji" and "rinit" in TRDizin®. The articles were grouped by specialty; namely, "Otorhinolaryngology (ORL)," "Pediatrics," adult "Pulmonary disease" and adult "Allergy/immunology," based on the affiliation of the first author. The total number of publications in each specialty group within the 25-year period were compared using a significance test for a difference in two proportions within the statistical assessment.
    Results: The 25-year results revealed 624 and 213 publications in the PubMed® and the TRDizin® databases, respectively. When the number of publications in a specific field in both databases was examined, the highest number of publications were identified in the ORL group, followed by the Pediatrics group. The number of publications in the ORL group was statistically higher than those in the "Pulmonary diseases" and "Allergy/immunology" groups in both the PubMed® and the TRDizin® databases (p=0.0001).
    Conclusion: The analysis of the number of 25-year allergic rhinitis publications from Turkey revealed that the academic interest of otolaryngologists in allergic rhinitis was unaffected, despite the challenges experienced in practice, with an increasing number of publications noted. When the number of 25-year publications was examined, ORL recorded the highest number of publications among all specialties.
    Keywords:  Allergic rhinitis; PubMed®; TRDizin®; Turkey; bibliometrics; otorhinolaryngology; publication
  26. Vet Pathol. 2021 Apr 28. 3009858211011943
      Veterinary pathologists are key contributors to multidisciplinary biomedical research. However, they are occasionally excluded from authorship in published articles despite their substantial intellectual and data contributions. To better understand the potential origins and implications of this practice, we identified and analyzed 29 scientific publications where the contributing pathologist was excluded as an author. The amount of pathologist-generated data contributions were similar to the calculated average contributions for authors, suggesting that the amount of data contributed by the pathologist was not a valid factor for their exclusion from authorship. We then studied publications with pathologist-generated contributions to compare the effects of inclusion or exclusion of the pathologist as an author. Exclusion of the pathologist from authorship was associated with significantly lower markers of rigor and reproducibility compared to articles in which the pathologist was included as author. Although this study did not find justification for the exclusion of pathologists from authorship, potential consequences of their exclusion on data quality were readily detectable.
    Keywords:  authorship; pathologist; pathology; reproducibility; research; rigor
  27. Zootaxa. 2021 Apr 16. 4963(1): zootaxa.4963.1.8
      In the majority of species and genus names in Decapoda Crustacea, the author(s) of the name equate with the author(s) of the work. In a relatively small number of cases, however, the author(s) of the name are either a subset of the authors of the work or are not an author on the work-a phenomenon herein termed "innies". We demonstrate that these two categories should be differentially interpreted according to Articles 50.1 and 50.1.1 of the ICZN Code. To promote stability in cited authorship of historical names, it is proposed that 1) if the author(s) of the name are also an author on the work, these should be universally accepted as "innies", irrespective of any further explanation in the text (including a mere attribution following the taxon name); and 2) that if the author(s) of the name are not an author(s) of the work, these should only be considered as "innies" if a more expansive explanation is given in the text, not merely an attribution of authorship to the taxon name.
    Keywords:  Authority citations, Crustacea, Decapoda, nomenclature, Crustacea
  28. Entropy (Basel). 2021 Apr 16. pii: 468. [Epub ahead of print]23(4):
      Proper peer review and quality of published articles are often regarded as signs of reliable scientific journals. The aim of this study was to compare whether the quality of statistical reporting and data presentation differs among articles published in 'predatory dental journals' and in other dental journals. We evaluated 50 articles published in 'predatory open access (OA) journals' and 100 clinical trials published in legitimate dental journals between 2019 and 2020. The quality of statistical reporting and data presentation of each paper was assessed on a scale from 0 (poor) to 10 (high). The mean (SD) quality score of the statistical reporting and data presentation was 2.5 (1.4) for the predatory OA journals, 4.8 (1.8) for the legitimate OA journals, and 5.6 (1.8) for the more visible dental journals. The mean values differed significantly (p < 0.001). The quality of statistical reporting of clinical studies published in predatory journals was found to be lower than in open access and highly cited journals. This difference in quality is a wake-up call to consume study results critically. Poor statistical reporting indicates wider general lower quality in publications where the authors and journals are less likely to be critiqued by peer review.
    Keywords:  data presentation; dental research; meta-research; publications; statistical reporting
  29. Ann Vasc Surg. 2021 Apr 23. pii: S0890-5096(21)00331-9. [Epub ahead of print]
    Keywords:  Article rejection; Bibliometric index; Citations; Impact factor; Retraction rate; Review failure
  30. Medicina (B Aires). 2021 ;81(2): 214-223
      In the present work we use text mining as a treatment tool for a large scientific database, with the aim of obtaining new information about all the publications signed by Argentine authors and indexed until 2019, in the area of life sciences. More than 75 000 articles were analysed, published in around 5000 media, signed by about 186 000 authors with a workplace in Argentina or in collaborations with Argentine laboratories. Using automated tools that were developed ad hoc, the text of around 70 800 abstracts was analysed, seeking, through non-supervised digital detection, the main topics addressed by the authors, and the relationship with health problems in Argentina and their treatment. Results are also presented regarding the number of publications per year, the journals that have published them, and their authors and collaborations. These results, together with the predictions that were obtained, could become a useful tool to optimize the management of resources dedicated to basic and clinical research.
    Keywords:  Argentina; scientific publications; text mining
  31. J Clin Epidemiol. 2021 Apr 26. pii: S0895-4356(21)00133-5. [Epub ahead of print]
      OBJECTIVE: To explore the impact of the Annals of Internal Medicine (AIM) data-sharing policy for randomized controlled trials (RCTs) in terms of output from data-sharing (i.e. publications re-using the data).STUDY DESIGN AND SETTING: Retrospective study. RCTs published in the AIM between 2007 and 2017 were retrieved on PubMed. Publications where the data had been re-used were identified on Web of Science. Searches were performed by two independent reviewers. The primary outcome was any published re-use of the data (re-analysis, secondary analysis, or meta-analysis of individual participant data [MIPD]), where the first, last and corresponding authors were not among the authors of the RCT. Analyses used Cox (primary analysis) models adjusting for RCTs characteristics (registration:
    RESULTS: 185 RCTs were identified. 106 (57%) mentioned willingness to share data and 79 (43%) did not. 208 secondary analyses, 67 MIPD and no re-analyses were identified. No significant association was found between intent to share and re-use where the first, last and corresponding authors were not among the authors of the primary RCT (adjusted hazard ratio = 1.04 [0.47-2.30]).
    CONCLUSION: Over ten years, RCTs published in AIM expressing an intention to share data were not associated with more extensive re-use of the data.
    Keywords:  Clinical Research; Data sharing; Meta-research; Open science; Randomized Controlled Trial; Re-use of data
  32. Neuroradiol J. 2021 Apr 30. 19714009211012363
      BACKGROUND: Transradial access for neurointerventional procedures was adopted and modified from cardiovascular intervention and is increasingly established as a safe and effective alternative to transfemoral catheterization. As social media influences public opinion on medical treatment, this study analyzes Twitter conversations to elucidate social media's depiction of transradial access as a neurointerventional tool.MATERIALS AND METHODS: Twitter hashtags #RadialFirst and #RadialForNeuro were evaluated using a mixed-method analysis of quantitative social media metrics and qualitative thematic analysis.
    RESULTS: Between January 2015 and April 2020, 104,146 tweets from 141 countries employed the hashtag #RadialFirst (2015 (1); 2016 (0); 2017 (22,804); 2018 (33,074); 2019 (38,352); 2020 (9,915 January-April)). These generated 226,909,374 impressions and were retweeted 80,120 times by 13,707 users. Media was present in 62.5% of tweets (e.g. wrist image, angiographic runs) but only 14.5% had a reference article. Physicians authored 70.8% of tweets; interventional cardiologists accounted for 83% of top 100 influencers. #RadialForNeuro is more nascent (6 posts in 2019; 323 posts January-April 2020), with 392,662 impressions, and 254 retweets by 177 users; physicians authored 35.6%. Compared to #RadialFirst, #RadialforNeuro tweets were more likely to include media (76%), less likely to include citations (9.7%), and more likely to discuss complications and troubleshooting techniques.
    CONCLUSION: Twitter activity regarding transradial access permits information dissemination and discussion on approach benefits and challenges. However, many posts arise from non-physician sources and lack links to peer-reviewed publication. The public should be mindful that tweets may reflect opinions, rather than experience or scientific evidence.
    Keywords:  Cerebral angiography; endovascular; neurovascular; radial; transradial
  33. Attach Hum Dev. 2021 Apr 26. 1-21
      This paper prospected the evidence synthesized in meta-analyses on child-parent attachment to discuss its implications for the future of attachment research. Based on the 75 identified meta-analyses, effect size benchmarks may need to be adjusted to small (r = .10), medium (r = .20), and large (r = .30). Topics of attachment meta-analyses predominantly (53%) reflected interest in testing theory. Bibliometric analysis of scientific publications (k = 7,595) that cited these meta-analyses reflect waxing uptake in work on interventions, mental health, and attachment anxiety/avoidance and waning uptake in work on attachment relationships and representations, except for the subtopics of sensitivity and fathers. Prospects for scientifically rigorous research are to be found in engagement with stakeholders working to address important societal challenges. Promoting nurturing care and reducing harm in child welfare contain "Goldilocks-problems" that are amenable to incremental progress while simultaneously advancing theory and methods.
    Keywords:  Attachment; bibliometrics; child welfare; meta-analysis; sustainable development goals
  34. Ann Oper Res. 2021 Apr 20. 1-59
      Humanitarian Operations (HO) have attracted the interest of professionals and academics, mainly due to their potential to reduce human suffering in disaster situations, leading to consolidation as a research field. With the evolution of the HO research field, synthesis of the knowledge and previous discoveries has become an important task for its advancement. In this study, a literature review based on bibliometric mapping techniques was carried out in order to identify the HO intellectual structure. As main results, we visually present the general emerging structure of the HO field using the VOS viewer software to devise the networks of the principal articles. The seminal research in this field is organized into two clusters: Humanitarian Supply Chain Management, and Distribution Optimization in Humanitarian Logistics. Regarding the emerging intellectual structure, three clusters were identified: Relationship Management and Big Data, Healthcare facility location, and Network flow restoration optimization. Finally, some gaps and questions for future research are presented.
    Keywords:  Bibliometric methods; Disasters; Humanitarian logistics; Humanitarian operations; Humanitarian supply chains; Scientific mapping
  35. Ann Dermatol. 2020 Oct;32(5): 383-387
      Background: Misclassification of study designs of journals can hinder the readers from assessing the strengths and weaknesses of the study and evaluating the applicability of the study in the real-world setting. However, it seems that it is common for authors to neglect to classify the study design.Objective: We aimed to evaluate the accuracy of the classification of study designs and examine the common errors.
    Methods: This descriptive study analyzed four Asian dermatology journals listed in the science citation index expanded from January 2018 to December 2018. We investigated discrepancies between author-reported and actual study designs. Design Algorithm for Medical Literature on Intervention (DAMI) was used to determine the actual study design.
    Results: Of the 177 papers analyzed, only 72 articles (40.7%) revealed their study design and among them, 23 articles (32.0%) showed discrepancies between the author-reported and the actual study designs. Case-control studies were the most commonly misclassified study designs by authors.
    Conclusion: There were considerable differences between the author-reported study design and the actual study design in Asian dermatology journals. Proper classification of study designs by the authors is essential to strengthen evidencebased medicine.
    Keywords:  Classification; Evidence-based medicine; Observational study; Research design
  36. PLoS One. 2021 ;16(4): e0250577
      Research-oriented hospitals are responsible for medical services tasks, medical education, and scientific research, playing an important role in medical research and application. The research efficiency of a clinical specialty is influenced by factors such as the characteristics of the specialty, the organizational atmosphere, and the clinical director's leadership. The present study aimed to describe the research efficiency of clinical specialties, explore the factors influencing it, and clarify the argument of co-evolution theory regarding the collaborative development of medical services, education, and research. Logistic regression and multiple linear regression were adopted to estimate the correlation between influencing factors and scientific research efficiency. Hospital H, which is representative of research hospitals in China, was taken as an example. Taking three efficiency values-comprehensive technical efficiency (CTE), pure technical efficiency (PTE), and scale efficiency (SE)-as dependent variables, the independent variables affecting research productivity were statistically analyzed. This study also examined the scientific research efficiency of 41 specialties between 2013 and 2017, and found that the independent variables affected CTE, PTE, and SE to various degrees. Collaborative innovation in medical education and research must be based on clinical research; how to balance medical and teaching quality, and research efficiency requires further discussion. While young people play a major role on the research team because of their creativity and initiatives, which improve CTE and PTE, high-level researchers with better research and leadership abilities lead to the rational allocation and effective utilization of resources, thus improving SE. In 2013-2017, discipline construction focused on scale expansion, resulting in the decline of SE in China. Therefore, this study suggests further improvements for the efficiency of clinical specialties in research hospitals.
  37. Int J Environ Res Public Health. 2021 Apr 28. pii: 4720. [Epub ahead of print]18(9):
      The relationship between sport and entrepreneurship is an emerging but constantly evolving research field, especially in recent years. This is an extremely important topic considering its positive impact on public health, social inclusion, economic development, and the promotion of intercultural exchange. This study has carried out a comprehensive and systematic review of literature on entrepreneurship and sport as tools for implementing social change. We used several bibliometric indicators in order to understand the current state of the literature, and scientific mapping analysis (keywords co-occurrence) to interpret the main theoretical areas of scientific interest. By searching the Scopus database, a total of 239 peer-reviewed articles were analyzed. The results showed the identification of six major recurring themes in the literature. For the purposes of our contribution, the recently developed line of research which considers sport as a tool for solving social problems through social change appears to be of particular importance. These data allow us to conclude that it is a highly multidisciplinary and active field. Suggestions for future lines of research and methodological limitations are discussed.
    Keywords:  bibliometric analysis; scientific mapping analysis; social change; social inclusion; sport entrepreneurship; sport for development
  38. BMC Plant Biol. 2021 Apr 24. 21(1): 198
      BACKGROUND: Scientific literature carries a wealth of information crucial for research, but only a fraction of it is present as structured information in databases and therefore can be analyzed using traditional data analysis tools. Natural language processing (NLP) is often and successfully employed to support humans by distilling relevant information from large corpora of free text and structuring it in a way that lends itself to further computational analyses. For this pilot, we developed a pipeline that uses NLP on biological literature to produce knowledge networks. We focused on the flesh color of potato, a well-studied trait with known associations, and we investigated whether these knowledge networks can assist us in formulating new hypotheses on the underlying biological processes.RESULTS: We trained an NLP model based on a manually annotated corpus of 34 full-text potato articles, to recognize relevant biological entities and relationships between them in text (genes, proteins, metabolites and traits). This model detected the number of biological entities with a precision of 97.65% and a recall of 88.91% on the training set. We conducted a time series analysis on 4023 PubMed abstract of plant genetics-based articles which focus on 4 major Solanaceous crops (tomato, potato, eggplant and capsicum), to determine that the networks contained both previously known and contemporaneously unknown leads to subsequently discovered biological phenomena relating to flesh color. A novel time-based analysis of these networks indicates a connection between our trait and a candidate gene (zeaxanthin epoxidase) already two years prior to explicit statements of that connection in the literature.
    CONCLUSIONS: Our time-based analysis indicates that network-assisted hypothesis generation shows promise for knowledge discovery, data integration and hypothesis generation in scientific research.
    Keywords:  IBM Watson; Knowledge networks; NLP; Plant science literature; Relationship extraction; Text mining
  39. Int J Womens Dermatol. 2020 Dec;6(5): 414-418
      Background: Gender disparity in research funding, leadership, authorship, and compensation in medicine is well documented, with most parameters favoring men over women. Gender differences in salary in dermatology have not been well studied.Objective: This study aimed to investigate the contribution of gender to dermatologists' compensation in the Veterans Affairs (VA) health care system.
    Methods: A retrospective cross-sectional study was conducted by identifying VA-affiliated dermatologists from the U.S. Department of VA website. The contributions of gender, years since graduation, h-index, academic appointment, race, and region on the publicly available salaries were analyzed using a linear-regression model to isolate the effects of gender and interaction with other variables.
    Results: This study included 247 VA dermatologists with publicly available salaries (114 women and 133 men). On univariate analyses, male dermatologists had significantly higher compensation than female dermatologists (p = .0333). However, male dermatologists also had significantly more years since graduation (p < .0001) and higher h-indices (p < .0001). Multivariate analysis showed that gender was not a significant contributor to salary. Instead, years since graduation (p < .0001), h-index (p = .0066), and academic appointment (p < .0001) contributed significantly to VA dermatologists' salaries. Region and race were not determinants of salary. Gender did not contribute to salary overall, but there was an interactive effect between gender and region (p = .0099). Compared with women, male dermatologists had significantly higher salaries in the Midwest (p < .0018).
    Conclusion: Our study revealed that VA hospitals have maintained gender equality in dermatologist compensation nationally, which could serve as a model to close salary gender gaps in other health care systems. Further research should focus on inclusion of VA physicians from different specialties, as well as across multiple years, to further characterize this observation.
    Keywords:  Academic titles; Dermatologist; Gender pay gap; H-index; Veterans Affairs health care system; Years since graduation