bims-evares Biomed News
on Evaluation of research
Issue of 2021‒03‒07
thirty-nine papers selected by
Thomas Krichel
Open Library Society

  1. Am J Orthod Dentofacial Orthop. 2021 Feb 27. pii: S0889-5406(21)00029-9. [Epub ahead of print]
      INTRODUCTION: Research on clear aligner treatment (CAT) has increased in recent years. In this study, we aimed to perform a bibliometric and visualized analysis to identify and critically assess the 50 most highly cited articles on CAT.METHODS: Web of Science was selected as a data source and consulted until March 2020 to identify all articles potentially relevant to the analysis. All the eligible articles were collected until 50 manuscripts were listed. Article-based parameters, journal-based parameters, and author-based parameters were registered to perform the bibliometric analysis. Keywords were automatically harvested from the selected articles to implement the visualized analysis.
    RESULTS: The search identified a total of 378 articles; the total number of citations of the selected articles varied from 15 to 112. The average number of citations per year varied from 1.15 to 13.83. The predominant study design was clinical (31.7%). Over the 15 journals in which the most cited articles were published, the American Journal of Orthodontics and Dentofacial Orthopedics published the majority of those included in the list (14) and also received the greatest number of citations (671). A total of 195 authors contributed to the 50 most cited articles; a significant portion of them (26) were unaffiliated with academic institutions. A total of 184 keywords were gathered from the article list.
    CONCLUSIONS: The number of citations on CAT is expected to grow steadily in parallel with the rising number of research projects. The present work identifies the most influential articles on CAT and their characteristics, placing emphasis on the journals, the authors, and the topics addressed.
  2. Arch Environ Occup Health. 2021 Mar 03. 1-10
      This study aimed to explore the evolution tracks of occupational low back pain (OLBP) studies during 2000 ∼ 2020 through strict and systematic bibliometric analysis. The analysis began with data retrieval in Web of Science using defined search terms associated with OLBP. Bibliometric tools, including BibExcel and CiteSpace, were employed to conduct performance analysis and co-citation network analysis. Totally, 4,127 documents were identified from 2000 to 2020. The United States contributed the most publications. The leading journals mainly focused on medicine and ergonomics. The co-citation analysis illuminated the development of OLBP studies and the top three published keywords were musculoskeletal disorder, risk factors, and fear avoidance. This paper can help researchers have a broader and deeper understanding of OLBP studies, provide a general insight into aggregate performance in the OLBP field, and find further research directions.
    Keywords:  Bibliometrics; Occupational low back pain (OLBP); co-citation network analysis; review
  3. Molecules. 2021 Feb 19. pii: 1085. [Epub ahead of print]26(4):
      Dimethyl fumarate is a cytoprotective and immunomodulatory drug used in the treatment of multiple sclerosis. We performed a bibliometric study examining the characteristics and trends of the top 100 cited articles that include dimethyl fumarate in the title. On 21 September 2020 we carried out an electronic search in the Web of Science (WOS), seeking articles that include the following terms within the title: dimethyl fumarate, BG-12, or Tecfidera. To focus our investigation on original research, we refined the search to include only articles, early access, others, case report, and clinical trials. We obtained a total of 1115 items, which were cited 7169 times, had a citation density of 6.43 citations/item, and an h-index of 40. Around 2010, there was a jump in the number of published articles per year, rising from 5 articles/year up to 12 articles/year. We sorted all the items by the number of citations and selected the top 100 most cited (T100). The T100 had 4164 citations, with a density of 37 citations/year and contained 16 classic research articles. They were published between 1961 and 2018; the years 2010-2018 amassed nearly 80% of the T100. We noted 17 research areas with articles in the T100. Of these, the number one ranking went to neurosciences/neurology with 39 articles, and chemistry ranked second on the T100 list with 14 items. We noticed that the percentage of articles belonging to different journals changed depending on the time period. Chemistry held the highest number of papers during 1961-2000, while pharmacology andneurosciences/neurology led the 2001-2018 interval. A total of 478 authors from 145 institutions and 25 countries were included in the T100 ranking. The paper by Gold R et al. was the most successful with 14 articles, 1.823 citations and a density of 140.23 citations/year. The biotechnological company Biogen led the T100 list with 20 articles. With 59 published articles, the USA was the leading country in publications. We concluded that this study analyzed the use of and research on dimethyl fumarate from a different perspective, which will allow the readership (expert or not) to understand the relevance of classic and recent literature on this topic.
    Keywords:  Tecfidera; bibliometric study; dimethyl fumarate; multiple sclerosis
  4. World Neurosurg. 2021 Mar 01. pii: S1878-8750(21)00279-5. [Epub ahead of print]
      OBJECTIVES: The purpose of current bibliometric analysis was to identify trends, and hot topics in research on lumbar spinal stenosis (LSS) over the past decade, for helping researchers explore new directions for future research in that area.METHODS: All research articles on LSS, written in English and indexed in the Web of Science database (WoS) between 2010 and 2020, were used. The visualization of network and in-depth bibliometric analysis, including the number of publications, countries, institutions, journals, authors, cited references, and keywords, were carried out with the help of CiteSpace.
    RESULTS: A total of 4033 papers (3577 original articles and 476 reviews) were identified and included in the study. The most productive year was in 2019. The Spine was the journal that published the highest number of articles and received the most citations. The most productive country and institutions in this field were the USA and Seoul National University, respectively. Kim HJ was the most prolific author, and Deyo RA ranked the first in the cited authors. The most cited article was published in 2010 by Deyo et al. and described the complications ad charges index for LSS. From the co-word cluster analysis, there were three frontiers in lumbar spinal stenosis: intervention, outcomes, and pathogenesis.
    CONCLUSION: We have summarized the literature on LSS in the past decade, including publication information, country, institution, authors, and journal. Research on minimally invasive surgery, outcomes, and gene therapies in LSS will be hot topics in the future.
    Keywords:  Bibliometrics; CiteSpace; Low Back Surgery; Lumbar Spinal Stenosis
  5. J Intensive Care Soc. 2021 Feb;22(1): 60-66
      Introduction: Social media is increasingly used in the dissemination of medical research. Traditional measures of the impact of a paper do not account for this. Altmetrics are a measure of the dissemination of a publication via social media websites. The purpose of this study is to ascertain if the altmetric attention score of an article is a reliable measure of the impact it has in the field of critical care medicine. To this end, we investigated if a correlation exists between future citation count and altmetric attention score.Methods: The top nine journals by impact factor in the field of critical care medicine were identified for 2014 and 2015. The 100 most cited articles from these journals were recorded to form the Scientific Impact Group, i.e. those with the greatest impact on the scientific community. The altmetric attention score was recorded for each article. The top 100 articles by altmetric attention score were also identified to form the Media Impact Group, i.e. those that generated the most online attention. Their citation counts' were recorded. Statistical analysis was performed on each group to identify a correlation between altmetric attention score and citation count.
    Results: There was a moderately positive correlation in the Scientific Impact Group, with a Spearman r score of 0.4336 (P = 0.0001). A weakly positive correlation was found in the Media Impact Group, with a Spearman r score of 0.3033 (P = 0.002).
    Conclusions: There is a positive correlation between traditional bibliographic metrics and altmetrics in the field of critical care medicine. Highly cited papers are more likely to generate online attention. However, papers that generate a lot of online attention are less likely to have a high citation count. Therefore, altmetric attention score is not a reliable predictor of future citation count in critical care medicine.
    Keywords:  Altmetrics; citation count; critical care; media impact; scientific impact; social media
  6. Healthcare (Basel). 2021 Feb 23. pii: 239. [Epub ahead of print]9(2):
      The novel coronavirus disease 2019 (COVID-19) is a global pandemic. This study's aim was to identify and characterize the top 100 COVID-19-related scientific publications, which had received the highest Altmetric Attention Scores (AASs). Hence, we searched Altmetric Explorer using search terms such as "COVID" or "COVID-19" or "Coronavirus" or "SARS-CoV-2" or "nCoV" and then selected the top 100 articles with the highest AASs. For each article identified, we extracted the following information: the overall AAS, publishing journal, journal impact factor (IF), date of publication, language, country of origin, document type, main topic, and accessibility. The top 100 articles most frequently were published in journals with high (>10.0) IF (n = 67), were published between March and July 2020 (n = 67), were written in English (n = 100), originated in the United States (n = 45), were original articles (n = 59), dealt with treatment and clinical manifestations (n = 33), and had open access (n = 98). Our study provides important information pertaining to the dissemination of scientific knowledge about COVID-19 in online media.
    Keywords:  COVID-19; altmetrics; bibliometric analysis; coronavirus; social media
  7. J Eur Acad Dermatol Venereol. 2021 Mar 03.
      BACKGROUND: In the past two centuries generations of dermatologists around the world have created an enormous number of publications. To our knowledge, no bibliometric analysis of these publications has been performed so far, nor have registered trials been analyzed to anticipate future publication trends.OBJECTIVES: To determine the global distribution of national publication productivity, most published topics, institutions and funding sources contributing most to publications and to anticipate future trends based on registered clinical trials.
    METHODS: Following pre-assessment on PubMed, Embase, Web of Science and Scopus, the number of publications for "dermatology" was determined for each of 195 countries, normalized per 1 Mio inhabitants and bibliometrically analyzed. Dermatology-related trials registered at were specified by the top-10 diagnoses for the top-10 countries.
    RESULTS: The search yielded 1,071,518 publications between 1832-2019 with the top-5 diagnoses being melanoma, basal cell carcinoma, psoriasis, pruritus/itch and atopic dermatitis. The top-3 countries with highest absolute numbers of publications were the USA (30.6%), Germany (8.1%) and the UK (8.1%), whereas Switzerland, Denmark and Sweden had the highest publication rates when normalized by inhabitants. The most productive affiliation was the Harvard Medical School, the leading funding source the National Institutes of Health. Currently, maximum number of trials are registered in the USA (8111), France (1543) and Canada (1368). The highest percentage of all dermatology-related trials in a specific country were: Melanoma in the Netherlands (24.8%), psoriasis in Germany (21.7%) and atopic dermatitis in Japan (15.9%).
    CONCLUSION: The top-10 countries including the USA, Canada, a few European and Asian countries contributed more than 3/4 of all publications. The USA hold the dominant leader position both in past publication productivity and currently registered trials. While most Western countries continue to focus their research on the top-10 topics, China and India appear to prioritize their scope towards other topics.
    Keywords:  Publication productivity; dermatology; global; output; research
  8. Brachytherapy. 2021 Mar 02. pii: S1538-4721(21)00035-0. [Epub ahead of print]
      PURPOSE: The aim of this study is to identify the leaders in research on prostate brachytherapy through a bibliometric analysis of the top 100 most cited publications in the field.METHODS AND MATERIALS: A broad search was performed with the term "prostate brachytherapy" using the Web of Science database to generate wide-ranging results that were reviewed by reading the abstracts and, if necessary, the articles to select the top 100 most cited publications.
    RESULTS: The median of the total citation count was 187 (range 132-1464). The median citation per year index (citations/year since publication) was 13.5 (range 6.3-379.0). In all publications, the first author was also the corresponding author. The top publishing countries of the first author included the United States (n = 78), Canada (n = 6), the UK (n = 5), and Germany (n = 4). The journal with the most publications was the International Journal of Radiation Oncology Biology Physics (n = 38). There were 27 more publications on low-dose-rate (LDR) than on high-dose-rate (HDR) (43 vs 16) among the top 100. HDR publications had only one first author that had three articles in comparison to LDR publications, which had four first authors, each with three articles on LDR. The United States was the leading country in 43.8% of HDR publications (n = 7) and 88.4% of LDR publications (n = 38).
    CONCLUSIONS: Our bibliometric analysis of the top 100 most cited publications clearly demonstrates the North American dominance in the publications of prostate brachytherapy, especially in LDR. However, European first authors were more frequent in HDR publications.
    Keywords:  Bibliometric analysis; Brachytherapy; Most cited publications; Prostate cancer
  9. Heliyon. 2021 Feb;7(2): e06273
      Economic research is vital for creating more suitable policies to facilitate economic growth. Employing a combination of descriptive and Bayesian analyses, this paper investigates the research landscape of the economics discipline in Vietnam, in particular, the leading affiliations in the field and how these institutions compare to each other in terms of productivity, the number of lead authors, new authors and publications' journal impact factor. We also examine the differences in the authors' productivity based on their age and gender. The dataset extracted from the SSHPA database includes 1,444 articles. The findings show that among top producers of economic research in Vietnam, seven are universities, leaving only one representative of research institutes. These top producers account for 52% of research output among 178 institutes recorded in the database. We also find a correlation between a researcher's affiliation, sex, and scientific productivity in Vietnam's economic discipline. Overall, publications by male researchers outnumber those by female ones in most of the top affiliations. The findings also indicate that 40-44 is the age group with the highest scientific productivity. Researchers' collaboration, which is observed through co-authorship, is on the rise in all of the top eight economic research affiliations. However, the quality of current Vietnam's scientific works in the discipline is questionable. Therefore, it is suggested that in order to sustain scientific productivity, economic researchers might need to balance the quantity and quality of their contributions.
    Keywords:  Bayesian analysis; Economics discipline; Scientific collaboration; Scientific publishing; Vietnam
  10. J Vet Med Educ. 2021 Mar 03. e20200073
      To study changes in JVME content, this article presents the results of an analysis of a purposeful sample (n = 537) and demographic analysis of all 1,072 articles published from 2005 to 2019. The findings were compared to a prior analysis of articles from 1974 to 2004. Article length increased, as did the number of authors and institutions per article. Female first author numbers grew at a greater rate than the proportion of female faculty at AAVMC-accredited colleges. Close to 85% of articles were by authors in the US, UK, Canada and Australia, while 40 other countries contributed the remainder. The primary topics of papers published from 2005 to 2019 were student affairs (17.3%), professional skills (15.1%), courses and curricula (12.7%), specialty/disciplinary training (12.5%), and technology/information resources (11.5%). The prevalence of articles with an identified research methodology grew from 14.2% in 1974-2004, to 55.9% (n = 300) in 2005-2019. Among research articles, 54.7% reported an intervention and 70.3% included a comparison. Random assignment to experimental or control conditions occurred in 32 articles (15.2%). Qualitative inquiry expanded, with 16.3% of research articles using this methodology alone. The most cited article was a review paper discussing the human-animal bond. Descriptions of courses and curricula constituted the majority of articles over the journal's lifespan, while no pattern was discerned between major reports in veterinary education and subsequent publications on that topic. Over the last 45 years, JVME has transitioned from a newsletter to a scholarly publication, with ongoing evolution.
    Keywords:  bibliometric analysis; educational research methods; educational scholarship; veterinary education
  11. Cureus. 2020 Dec 31. 12(12): e12411
      Introduction Research can be used to enhance the competitiveness of an application and is associated with a successful match. However, current reports regarding the publication record among prospective dermatology residents may be inaccurate. We sought to accurately assess the research credentials of matched dermatology residency candidates at the time of application. Methods We performed a bibliometric analysis to identify published articles of 1152 matched dermatology candidates and calculated the h-index of each applicant at the time of application. Details on article type, first authorship, and dermatology-relatedness of articles were collected. Results The median number of publications was two and the median h-index was 0. At the time of residency application, one-quarter of matched dermatology candidates (24%, n=278) possessed no publications. Over time, the median number of publications (R 0.10, p<0.001) and h-index (R 0.07, p=0.014) of matched applicants increased. The proportion of first-authored articles, dermatology-related papers, and each article type remained constant across application cycles (p>0.0500). An additional graduate degree, completion of a research fellowship, and graduation from a non-US medical school were independently associated with greater research credentials (p<0.0500). Conclusions Each year, applicants are publishing more articles and have a greater scholarly impact than in previous application cycles. However, the verified publication volume of matched dermatology applicants is strikingly lower than the values reported in national statistics.
    Keywords:  authorship; bibliometrics; dermatology; h-index; publications; residency and internship
  12. Surg Neurol Int. 2021 ;12 62
      Background: Citation analysis reflects the scientific recognition and influential performance of a published article within its field. We aim to identify the top 100 most-cited articles on astrocytoma using this bibliometric analysis method.Methods: In May 2020, we performed a thorough search in the Scopus database using the word "Astrocytoma." The top 100 most-cited articles were arranged based on citation count in descending order. The resultant articles were then analyzed with an assessment of pertinent factors.
    Results: The most-cited articles on astrocytoma had been cited 23,720 times. The top-cited article received a total of 682 citations, with an average of 34.1 citations annually. The list comprised eight clinical trials, in which the highest cited article received 625 citations. Articles were published from 1975 to 2015 with the 1995-2005 era as the most prolific period. Neuropathology studies were the most studied category, followed by clinical studies. The United States of America was the most significant contributor, with 49 published articles. The University of California San Francisco was the most contributing institution by producing 11 articles. Articles were published in 32 different journals led by the Cancer Research Journal, with a total of 12 publications. Approximately 160 authors contributed to the list in which Scheithauer, B.W. contributed the most with a total of eight articles.
    Conclusion: This report clustered the most impactful articles on astrocytoma. It serves as an adequate tool to identify publication trends and helps in achieving evidence-based clinical practice.
    Keywords:  Astrocytoma; Bibliometric; Citation analysis; Low-grade glioma; Neurosurgery
  13. J Gen Intern Med. 2021 Mar 02.
      BACKGROUND: The Research Project Grant (R01) is the oldest grant mechanism used by the National Institutes of Health (NIH). Receiving an R01 award is often taken as a sign of scientific success. We presented normative data on multiple productivity and impact metrics for a more objective assessment of funded grants' scientific success.METHODS: All initial R01 grants awarded by NIH in the year 2000 were prospectively followed and evaluated using the numbers of publications and citations, as well as the h-indices at the grant level. We examined the variability, time trends, and relations among these metrics to better understand the funded projects' cumulative output and impact.
    RESULTS: In the 20 years since initial funding, 4451 R01 grants generated a total of 55,053 publications. These publications were cumulatively cited 3,705,553 times over 736,811 citation years. The median number of publications was 8 (25th, 75th percentiles 4, 17) per grant for the entire 20-year duration. The median number of citations and the median h-index were 441 (25th, 75th percentiles 156, 1061) and 7 (25th, 75th percentiles 4, 13) per grant, respectively. The time courses of publication, citation, and accumulation of h-index were highly variable among the awarded grants. Although the metrics were correlated within an award, they reflected the grant's success in different domains.
    CONCLUSION: Numbers of publications, citations, and h-indices vary greatly among funded R01 grants. When used together, these metrics provide a more complete picture of the productivity and long-term impact of a funded grant.
    Keywords:  NIH grants; h-index; research productivity
  14. Front Oncol. 2020 ;10 627891
      Objectives: To identify the cooperation of authors, countries, institutions and explore the hot topics' prospects regarding research of prostate diseases and erectile dysfunction (ED).Methods: Publications on research of prostate diseases and ED were retrieved from the Web of Science Core Collection (WoSCC). Bibliometric analyses were performed using VOSviewer and CiteSpace software. Network maps were generated to evaluate the collaborations between different authors, countries, institutions, and keywords.
    Results: A total of 2,599 articles related to study of prostate diseases and ED were identified. We observed gradually increasing in the number of publications from 1998 to 2016, and the trend was to be relatively stable in the past 3 years. Journal of Sexual Medicine (243 papers) owned the highest number of publications and Journal of Urology was the most co-cited journal. Mulhall John P (52 papers) was the top most productive authors and Mcvary Kebin T with the largest numbers of citations (1,589 co-citations) during the past decades. There were active collaborations among the top authors. The USA was the leading contributor in this field with 1,078 papers. Active cooperation between countries and between institutions was observed. The main hot topics included matters related to erectile dysfunction, prostate cancer, quality-of-life, radical prostatectomy, sexual function, and BPH.
    Conclusion: Bibliometric analysis provides a comprehensive overview of the development of scientific literature, allowing relevant authors and research teams to recognize the current research status in this field and at the same time provide a reference for formulating future research directions.
    Keywords:  benign prostatic hyperplasia; bibliometric analysis; erectile dysfunction; prostate cancer; radical prostatectomy
  15. Environ Sci Pollut Res Int. 2021 Feb 27.
      This study aims to provide a detailed overview of environmental Kuznets curve hypothesis using bibliometric analysis for the Web of Science (WOS) database. Our analysis provides an overview of research trends, journals and most influential authors. China has contributed the most scientific publications; followed by the USA, Turkey, and Pakistan. Muhammad Shahbaz, Beijing Institute of Technology, and Environmental Science and Pollution Research are the most productive author, research institute, and research journal in EKC publications. Trend analysis of researchers, academic and country-level, reveal that publications in the environmental Kuznets curve have upward trend; also, cocitation analysis indicates that EKC publications are closely related. "Economic growth and income inequality" (1955) by Simon Kuznets is considered to be the basic literature, and "environmental Kuznets curve hypothesis: A Survey" by Dinda (2004) is the most cited research article in the literature. Keywords and abstracts analysis further reveals that carbon emissions, renewable energy, energy consumption, economic growth, and sustainable development are the hot topics in current literature. We propose that joint research projects between industrial and emerging economies will promote research activities.
    Keywords:  Bibliometric analysis; EKC hypothesis,Literature review; Environmental Kuznets curve
  16. Int J Environ Res Public Health. 2021 Feb 11. pii: 1764. [Epub ahead of print]18(4):
      Energy poverty is one of the main challenges facing humanity in the 21st century. Research on energy poverty is becoming a common focus of scholars in many areas. Bibliometrics can help researchers dig deep into the information of specific research fields from a quantitative perspective. In this study, we collected 1018 research papers in the field of energy poverty published in the period 1999-2019 from the Web of Science databases and conducted a bibliometric analysis on them. Cleaning and screening of sample papers, matrix construction, and visualization were performed using Bibliometrix, VOSviewer, and HistCite, summarizing the internal and external characteristics of the papers. With regard to external characteristics, a total of 982 research institutions in 80 regions conducted research in this field. There is extensive cooperation between the countries, and the UK, the USA, Australia, and Italy play the most active role in the cooperation network. With regard to internal characteristics, we found the two most representative citation paths: one path starts from the concerns of energy-poor groups and stops at an ethical discussion on energy poverty; the second path is based on the existing technological path, continuously developing coping policies, evaluation methods, and a conceptual framework for dealing with energy poverty. Furthermore, through coupling analysis, we discovered four focuses of energy poverty research: improvement of definition, improvement of evaluation methods, effects of coping policy, and energy justice. Through a comprehensive analysis of existing papers, this paper reveals some limitations of previous studies and recommends some promising directions for future research on energy poverty.
    Keywords:  bibliometrics; energy consumption; energy poverty; social network analysis
  17. World J Mens Health. 2021 Feb 08.
      PURPOSE: The objective of this scientometric analysis was to recognize the top 100 cited articles on 'Male infertility and Antioxidants' and analyze its publication characteristics.MATERIALS AND METHODS: The Scopus database was used to retrieve related articles and the top 100 identified based on citation rate.
    RESULTS: The articles were published in 56 journals between 1995 and 2019 with a median (interquartile range) citation score of 17 (5-62). Among the top 100 articles, 69 were clinical studies, which included controlled and blinded (33.33%), prospective (27.54%), randomized-controlled trials (26.09%), uncontrolled (11.59%), and retrospective (1.45%) studies. In addition to conventional semen parameters, advanced sperm function tests such as oxidative stress (51%) and sperm DNA damage (23%) were reported. Pregnancy rate (33%) was found to be the most reported reproductive outcome. Antioxidant therapy was mostly investigated in male cohorts with sperm abnormalities such as asthenozoospermia (28%) and clinical conditions such as idiopathic male infertility (20%), varicocele/varicocelectomy (17%) and general male infertility (16%).
    CONCLUSIONS: The most influential publications on antioxidants and male infertility were identified for the first time in the literature. This will serve as a reliable source of information for researchers and clinicians alike.
    Keywords:  Antioxidants; Clinical trial; Infertility, male; Publications; Research
  18. Sao Paulo Med J. 2021 Jan-Feb;139(1):pii: S1516-31802021000100003. [Epub ahead of print]139(1): 3-9
      BACKGROUND: The pandemic of the new coronavirus has culminated in a scientific race to seek knowledge about this virus and its treatments, vaccines and preventive strategies, in order to reduce its impact on healthcare and economics worldwide. Hence, it is important to recognize the efforts of researchers who are at the forefront of investigations relating to the new coronavirus.OBJECTIVE: The present study was carried out with the aim of analyzing the world scientific production relating to COVID-19.
    DESIGN AND SETTING: Exploratory and descriptive bibliometric study conducted in the city of Teresina (PI), Brazil.
    METHOD: ISI Web of Knowledge/Web of Science (WOS) was chosen as the database. Data-gathering was carried out in May 2020. The data analysis was performed using the HistCiteTM software, version 9.8.24, and the VOSviewer bibliometric analysis software, version 1.6.8.
    RESULTS: 2,625 published papers that included descriptors within the scope of this investigation were identified. These articles were published in 859 different journals that are indexed in WOS, by 9,791 authors who were linked to 3,365 research institutions, located in 105 countries.
    CONCLUSION: Ascertaining scientific production through a bibliometric analysis is important in order to guide researchers on what has already been produced and what is being researched, so as to be able to address gaps in knowledge through future research.
  19. BDJ Open. 2021 Mar 01. 7(1): 13
      OBJECTIVE: This study aimed to establish the current situation, intellectual base, hotspots, development trends, and frontiers of oral health literacy (OHL) from the literature.METHODS: We analyzed 1505 bibliographic records dated between January 1990 and December 2020 retrieved from the Web of Science Core Collection and the Scopus database. We used CiteSpace for word frequency analysis, co-occurrence analysis, co-citation analysis, clustering analysis, and burst analysis.
    RESULTS: The total number of publications increased year-on-year, with the majority of publications coming from the USA. Most studies focused on the relationship between (oral) health literacy and oral health, and the development of OHL instruments. The top 10 keywords by frequency were "health literacy", "oral health", "attitude to health", "dental caries", "adult", "children", "dental care", "knowledge", "questionnaire", and "adolescent". The keyword with the highest burst intensity was "dental health education".
    CONCLUSIONS: OHL research is a thriving field. The field is focused on the development of an OHL instrument and health promotion practice. Strategic cooperation among countries, institutions, authors, hospitals, and communities will be important to encourage further OHL research and address oral health problems.
  20. Medicina (Kaunas). 2021 Feb 17. pii: 172. [Epub ahead of print]57(2):
      Background and Objectives: The programs of enhanced recovery after surgery are the new revolution in surgical departments; however, features of this concept have not been systematically explored. Therefore, the purpose of this study was to explore Enhanced recovery after surgery (ERAS)-related research using bibliometric analysis. Materials and Methods: The search strategy of ERAS programs was conducted in the Web of Science database. Bibliometric analysis was further performed by Excel and Bibliometrix software. The relationship between citation counts and Mendeley readers was assessed by linear regression analysis. Results: 8539 studies from 1994-2019 were included in the present research, with reporting studies originating from 91 countries using 18 languages. The United States (US) published the greatest number of articles. International cooperation was discovered in 82 countries, with the most cooperative country being the United Kingdom. Henrik Kehlet was found to have published the highest number of studies. The journal Anesthesia and Analgesia had the largest number of articles. Linear regression analysis presented a strong positive correlation between citations and Mendeley readers. Most research was related to gastrointestinal surgery in this field. Conclusion: This bibliometric analysis shows the current status of ERAS programs from multiple perspectives, and it provides reference and guidance to scholars for further research.
    Keywords:  bibliometric analysis; complications; disease management; enhanced recovery after surgery; patient outcome assessment
  21. J Orthop Surg Res. 2021 Mar 04. 16(1): 174
      BACKGROUND: Hip fracture is common and carries high morbidity and mortality; thus, it has become a vital concern. We aim to analyse the present status, worldwide trends in hip fracture and state of clinical research.METHODS: Publications from 2000 to 2019 were retrieved from the Web of Science database and analysed using a bibliometric methodology. VOSviewer software was utilised for analysis.
    RESULTS: In total, 6139 publications were included, and publications increased annually from 152 in 2000 to 592 in 2019. U.S. researchers have produced the most publications, the highest H-index and the greatest number of citations. Osteoporosis International has published the most papers on the topic. Leading researchers, contributing institutions, their cooperative relationships and scientific masterpieces have been identified. The publications can be divided into five clusters: 'mortality', 'surgical management', 'rehabilitation', 'osteoporosis' and 'epidemiology'. A clear developing trend was described, which began with fracture epidemiology and prevention, transitioned to perioperative management, orthogeriatric care and patient safety and then to functional recovery, disease burden and national audits in recent times.
    CONCLUSIONS: Hip fractures result in conditions that extend far beyond orthopaedics concerning epidemiology and preventive medicine, internal medicine and endocrinology, as well as critical care and gerontology. Interest, research and publications are on the rise.
  22. Ying Yong Sheng Tai Xue Bao. 2021 Feb;32(2): 763-770
      To explore the historical evolution and current status of the EwE (Ecopath with Ecosim) modelling research, the core dataset and extended dataset were collected by topic retrieval and citation indexing methods from the "Web of Science" from 1984 to 2020. The bibliometric analysis and mapping knowledge were performed by CiteSpace software, focusing on literature distribution, research forces, research theme, and hotspot evolution. The results showed that the annual publications in the EwE model researches were increasing, covering multi-disciplinary fields. Christensen, Walters, and Pauly were representative scholars with an important role in model development and relevant international cooperation. In the early stage, EwE model was usually applied to solve ecosystem problems, including spatial-temporal dynamic of structure and function, and the ecosystem effects of fisheries. Currently, marine resource management, ecosystem modelling, marine protected areas and ecosystem indicators had become the key themes. The research hotspots shifted from model development and food web structure to ecosystem forecasting and resource management, which would provide scientific evidence for ecosystem-based aquatic resource management and the construction of protected area in marine.
    Keywords:  CiteSpace; Ecopath with Ecosim (EwE); co-citation analysis; hotspot evolution
  23. Polymers (Basel). 2021 Feb 22. pii: 647. [Epub ahead of print]13(4):
      Collecting information from previous investigations and expressing it in a scientometrics study can be a priceless guide to getting a complete overview of a specific research area. The aim of this study is to explore the interrelated connection between alginate, gelatine, and hydroxyapatite within the scope of bone tissue and scaffold. A review of traditional literature with data mining procedures using bibliometric analyses was considered to identify the evolution of the selected research area between 2009 and 2019. Bibliometric methods and knowledge visualization technologies were implemented to investigate diverse publications based on the following indicators: year of publication, document type, language, country, institution, author, journal, keyword, and number of citations. An analysis using a bibliometric study found that 7446 papers were located with the keywords "bone tissue" and "scaffold", and 1767 (alginate), 185 (gelatine), 5658 (hydroxyapatite) papers with those specific sub keywords. The number of publications that relate to "tissue engineering" and bone more than doubled between 2009 (1352) and 2019 (2839). China, the United States and India are the most productive countries, while Sichuan University and the Chinese Academy of Science from China are the most important institutions related to bone tissue scaffold. Materials Science and Engineering C is the most productive journal, followed by the Journal of Biomedical Materials Research Part A. This paper is a starting point, providing the first bibliometric analysis study of bone tissue and scaffold considering alginate, gelatine and hydroxyapatite. A bibliometric analysis would greatly assist in giving a scientific insight to support desired future research work, not only associated with bone tissue engineering applications. It is expected that the analysis of alginate, gelatine and hydroxyapatite in terms of 3D bioprinting, clinical outcomes, scaffold architecture, and the regenerative medicine approach will enhance the research into bone tissue engineering in the near future. Continued studies into these research fields are highly recommended.
    Keywords:  alginate; bone tissue; gelatine; hydroxyapatite; scaffold
  24. Int J Environ Res Public Health. 2021 Feb 22. pii: 2110. [Epub ahead of print]18(4):
      The Coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health crisis with unmatched outcomes and effects. This pandemic has caused an infodemic of article publication in scientific journals. Dental journals have been active in the publication of COVID-19 related articles from the beginning of the pandemic. In this cross-sectional survey, we present an analysis of the scientific output of dental journals on COVID-19. The PubMed COVID-19 database was searched with the "Dental Journals" filter. Data including journal name, country, month of publication and number of citations were recorded. Science mapping analysis of the most used keywords was also performed. The search retrieved a total of 659 articles, of which 28 were excluded. Oral Diseases has published the most COVID-19 articles (15.1%), followed by the British Journal of Oral and Maxillofacial Surgery (8.6%) and the Journal of Dental Education (7.9%). Most of the articles were from researchers from the United States (168), United Kingdom (120) and Brazil (83). The number of citations of the published articles ranged from 0 to 406, with most articles (64.2%) having no citations. Science Mapping analysis revealed that the most used keywords were coronavirus infections, pandemics and humans. The dental community has been active in the publication of COVID-19 articles from the beginning of the pandemic. The papers published by dental journals explore issues such as the management of clinical practices during the outbreak, infection control in the dental setting, signs and symptoms of COVID-19 affecting the oral cavity, and the impact of the COVID-19 pandemic on educational and clinical programs.
    Keywords:  COVID-19; PubMed; SARS-COV-2; dental articles; dentistry
  25. World J Transplant. 2021 Feb 18. 11(2): 7-15
      World Journal of Transplantation (WJT) was launched in December 2011. While we are celebrating WJT's 10-year anniversary, we are very proud to share with you that since its first issue, WJT has published 312 articles, which have been cited 2786 times (average cites per article of 9.0). Together with an excellent team effort by our authors, Editorial Board members, independent expert referees, and staff of the Editorial Office, WJT advanced in 2020. In this editorial, we summarize the journal's bibliometrics, including its citation report, published articles in 2020, peer review rate and manuscript invitation metrics, as well as its Editorial Board members and existing problems of WJT. The overall aim of this editorial is to promote the development of WJT in 2021. We appreciate the continuous support and submissions from authors and the dedicated efforts and expertise by our invited reviewers. This collective support will allow us to be even more productive in 2021. In addition, we commit to working with you all to raise the academic influence of WJT over the upcoming year. Finally, on behalf of WJT, we wish you and your families the best for the New Year.
    Keywords:  Articles; Citations; Country; Development; Editorial Board; Manuscript type; Peer-review; Problems; Topics; World Journal of Transplantation
  26. J Womens Health (Larchmt). 2021 Mar 05.
      Background: For the past two decades, there has been increased interest from medical journals and calls to action from various organizations such as the National Institutes of Health to study sex differences in cardiovascular (CV) disease. It is unknown whether this emphasis has translated to a growth in publications addressing sex differences in CV disease. Materials and Methods: We performed a bibliometric analysis of all CV publications from 2006 to 2015. The National Library of Medicine's PubMed database was searched for articles containing the phrases "cardiac," "cardiovascular" or "cardiology," in the first author affiliation field. This was followed by a subsequent search for publications containing any of the following phrases in the title and/or abstract: "woman," "women," "female," "females," "gender," or "sex." The presence of such terms defined the publication as sex-specific. Trends over time were analyzed for specified subgroups, including publication category and funding source. Results: A total of 189,543 CV publications were identified, out of which there were 24,615 (12.99%) sex-specific publications. For the 10-year period, there were no significant changes in the relative proportion of sex-specific publications. When specific publication categories were analyzed, there were significant proportional increase of sex-specific publications in general articles category, but not for reviews, clinical trials, meta-analysis, or letters. Conclusion: Despite calls for greater attention, only a small fraction of publications for the past decade have reported on sex differences. There was no significant proportional growth of sex-specific publications for a recent 10-year period, except for the general research articles.
    Keywords:  NIH funding; cardiovascular publications; sex-specific
  27. Int J Environ Res Public Health. 2021 Feb 22. pii: 2131. [Epub ahead of print]18(4):
      The study of human rights (HR) is vital in order to enhance the development of human beings, but this field of study still needs to be better depicted and understood because violations of its core principles still frequently occur worldwide. In this study, our goal was to perform a bibliometric performance and network analysis (BPNA) to investigate the strategic themes, thematic evolution structure, and trends of HR found in the Web of Science (WoS) database from 1990 to June 2020. To do this, we included 25,542 articles in the SciMAT software for bibliometric analysis. The strategic diagram produced shows 23 themes, 12 of which are motor themes, the most important of which are discussed in this article. The thematic evolution structure presented the 21 most relevant themes of the 2011-2020 period. Our findings show that HR research is directly related to health issues, such as mental health, HIV, and reproductive health. We believe that the presented results and HR panorama presented have the potential to be used as a basis on which researchers in future works may enhance their decision making related to this field of study.
    Keywords:  SciMAT; bibliometric analysis; co-word analysis; human rights; strategic intelligence
  28. Curr Pharm Teach Learn. 2021 Mar;pii: S1877-1297(20)30326-9. [Epub ahead of print]13(3): 228-237
      INTRODUCTION: Research and scholarship are core elements of the academic mission. Yet fulfilling institutional and accreditation requirements for scholarly activity can be challenging, particularly for teaching-intensive institutions. This paper describes strategies for employing a teacher-scholar model to stimulate and sustain scholarly activity.METHODS: Metrics of scholarly productivity were programmatically assessed and reported for at least five years following implementation of sixteen different strategic initiatives at three teaching-intensive colleges of pharmacy. Data reported included publications (original peer-reviewed publications, case reports, review articles), presentations (posters, podiums, and continuing education sessions), peer-reviewed published abstracts, grants awarded, and total extramural funding per annum. Faculty and student engagement in scholarship was indicated by authorship on at least one scholarly work.
    RESULTS: Broad increases in metrics of scholarly productivity were observed, while the timing and degree of change varied (1.4-fold to 10.4-fold, across all institutions, all years). Notably, the most robust growth was observed in grantsmanship and the number of faculty and student contributors to scholarly works. A key observation was that increased scholarly output was sustained, as during the most recent three-year period publications increased 1.6-fold, grants and extramural funding increased 3.4- and 15.8-fold, respectively, and faculty and student contributors increased 1.8- and 4.5-fold, respectively.
    CONCLUSIONS: Overall, these data point to a substantive, detailed approach for increasing scholarship at diverse, teaching-intensive institutions by implementing cost-conscious strategies, including clear ties between scholarly effort/productivity and faculty performance/advancement, strong faculty development and mentoring, institutional commitments to infrastructure and research budgets, and student engagement in scholarly activities.
    Keywords:  Faculty development; Research; Scholarship; Teacher-scholar
  29. Pharmacy (Basel). 2021 Feb 13. pii: 40. [Epub ahead of print]9(1):
      Pharmacists are expected to participate in the conduction of research to advance the profession and health care broadly. Additional opportunities for pharmacist research engagement have emerged with the increased integration of clinically trained pharmacists into interprofessional care teams. Research conducted over the past four decades has demonstrated an increasing trend of pharmacist-authored publications in medical journals. The purpose of this study was to build upon this work and investigate trends in pharmacist-authored original research publications within the JAMA Network over the past 20 years. A descriptive study design was used to retrospectively evaluate trends in the numbers of pharmacist-authored publications and authorship within those publications in nine JAMA Network journals. Data were aggregated into ten-year time periods (2000-2009 and 2010-2019) and compared using chi-square and Fisher's exact tests. Overall, pharmacist-authored publications significantly increased over the ten-year period (2.0% to 3.0%, p < 0.001), including in five specific journals: JAMA, JAMA Dermatology, JAMA Neurology, JAMA Ophthalmology, and JAMA Surgery. There was no change in first-and senior-authored publications. While the overall pharmacist publication trend was positive, room for significant growth remains. A deeper understanding of the barriers and facilitators to pharmacist engagement in research is needed, along with strategies to enhance pharmacist research training.
    Keywords:  authorship; bibliometrics; medical journals; pharmacy research; publishing trends; research training
  30. Langenbecks Arch Surg. 2021 Feb 28.
      PURPOSE: To present social media (SoMe) platforms for surgeons, how these are used, with what impact, and their roles for research communication.METHODS: A narrative review based on a literature search regarding social media use, of studies and findings pertaining to surgical disciplines, and the authors' own experience.
    RESULTS: Several social networking platforms for surgeons are presented to the reader. The more frequently used, i.e., Twitter, is presented with details of opportunities, specific fora for communication, presenting tips for effective use, and also some caveats to use. Details of how the surgical community evolved through the use of the hashtag #SoMe4Surgery are presented. The impact on gender diversity in surgery through important hashtags (from #ILookLikeASurgeon to #MedBikini) is discussed. Practical tips on generating tweets and use of visual abstracts are presented, with influence on post-production distribution of journal articles through "tweetorials" and "tweetchats." Findings from seminal studies on SoMe and the impact on traditional metrics (regular citations) and alternative metrics (Altmetrics, including tweets, retweets, news outlet mentions) are presented. Some concerns on misuse and SoMe caveats are discussed.
    CONCLUSION: Over the last two decades, social media has had a huge impact on science dissemination, journal article discussions, and presentation of conference news. Immediate and real-time presentation of studies, articles, or presentations has flattened hierarchy for participation, debate, and engagement. Surgeons should learn how to use novel communication technology to advance the field and further professional and public interaction.
    Keywords:  Gender diversity; Impact; Influence; Internet; Research communication; Research dissemination; Social media; Surgical research
  31. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2021 Feb 28. 43(1): 92-100
      Objective To analyze the research status,hotspots,and frontiers of atherosclerosis genomics from 2010 to 2019.Methods CiteSpace software was used to conduct data statistics and visual analysis on countries,institutions,authors,journals,co-cited papers,and keywords of the related papers published in the Web of Science from 2010 to 2019.Results A total of 1021 papers in English were included,and the annual number of publications generally showed an upward trend.The knowledge base in the research of atherosclerosis mostly focused on the genetic risk sites and biomarkers for coronary artery diseases such as coronary heart disease,myocardial infarction,and dyslipidemia.The related journals mainly involved the fields of molecular biology,biology,genetics,immunology,medicine,pharmacy,and clinical medicine.The latest research in atherosclerosis concentrated on genome-wide association study,DNA methylation,microRNA,messenger RNA and so on.The research frontiers involved long noncoding RNA,DNA methylation,and immune metabolism.Conclusion The studies in atherosclerotic genomics have gradually increased.
    Keywords:  CiteSpace; atherosclerosis; genomics; research hotspot; visual analysis
  32. Nature. 2021 Mar;591(7849): 333-334
    Keywords:  Authorship; Careers; Publishing
  33. TechTrends. 2021 Feb 24. 1-12
      Using large-scale, public data sources, this editorial provides a high-level description of educational technology trends leading up to and encompassing the year 2020. Data sources included (a) 17.9 million Facebook page posts by K-12 educational institutions in the U.S., (b) 131,760 tweets to the #EdTech hashtag on Twitter, and (c) 29,636 educational technology articles in the Scopus database. We provide a variety of descriptive results in the form of participation frequency charts, keyword matches, URL domain link counts, co-occurring hashtags, tweet text word trees, and common word and bigram frequencies. Results from the analysis of Facebook posts indicated that (a) schools increasingly used the platform over time, (b) the pandemic increased frequency (but not the nature) of use, (c) schools are progressively sharing more media, information, and tools, and (d) some of these tools align with trends identified by Weller (2020) while others do not. Analysis of tweets indicated that (a) discussions in 2020 revolved around "remote learning" and related topics, (b) this emphasis shifted or morphed into "elearning" and "online learning" as the year progressed, (c) shared posts were primarily informational or media-based, and (d) the space was heavily directed by a relatively small group of Superusers. Last, analysis of articles in Scopus indicated that (a) online learning is historically the most-researched topic in the field, (b) the past decade reflects a shift to more "open" and "social" topics, and (c) there seems to be a lag or disconnect between emergent high-interest technologies and research. Taken together, we conclude that these results show the field's preparation for addressing many challenges of 2020, but propose that, moving forward, we would be better served by embracing greater philosophical plurality and better addressing key issues, including equity and practicality.
  34. Nurse Educ. 2021 Mar 04.
      BACKGROUND: The Doctor of Nursing Practice (DNP) nurse is recognized as a practice scholar in nursing and leadership; moreover, the volume of published scholarship from DNP authors is expanding.PURPOSE: The aim of this research was to quantify and analyze DNP-authored peer-reviewed journal publications from 2012 through 2018.
    METHODS: This was a descriptive analysis of DNP graduate publications found in the WorldCat database from 2012 through 2018.
    RESULTS: Nearly 2000 (n = 1903) DNP-authored, peer-reviewed journal publications were extracted. Doctor of Nursing Practice-authored publications increased 136% from 2012 to 2018, including 1059 (56%) with DNP authors as first authors and 494 (26%) from DNP graduate solo authors. There were 1179 collaborative and interprofessional publications (62%).
    CONCLUSIONS: The findings in this research demonstrate an increase in the number of DNP-authored scholarly publications since 2012. Scholarly publications by DNP authors expand the dissemination of knowledge and offer an avenue to improve health outcomes nationally and globally.
  35. Aesthetic Plast Surg. 2021 Mar 03.
      OBJECTIVE: Plastic surgery is one of the most competitive and innovative fields in medicine. The role of the academic plastic surgeon continues to grow beyond clinical care, and many surgeons have pursued advanced degrees (AD) to expand their professional skillset. We present an analysis of ADs of academic plastic surgery faculty in the USA, with consideration of timing of AD attainment.METHODS: All academic plastic surgery faculty members were identified from plastic surgery program websites, as recognized by the American Council of Academic Plastic Surgeons. ADs were defined as additional degrees beyond the primary medical degree. Outcomes included timing of AD attainment, residency rankings, institutional standings, and research productivity.
    RESULTS: 949 faculty members were identified, and 167 had ADs. The most common ADs were PhD (30%), MS/MSc (18%), and MBA/EMBA (17%). Timing of AD attainment was available for 146 faculty members (84.7%). Having an AD before residency was associated with matching into higher-tiered and integrated residency programs (both p < 0.05). For attending physicians, having an AD was associated with more journal editorial board positions, more publications, higher H-index, receiving NIH funding, and median number of NIH grants (adjusted for years in practice, all p<0.05). Institutional analysis revealed that employing more faculty with an AD was associated with having an integrated residency program, higher residency research ranking, and higher tier integrated residency (all p < 0.05).
    CONCLUSION: ADs are growing in popularity in academic plastic surgery and are temporally associated with specific advantages in terms of residency placement, research productivity, and institutional standing.
    LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors .
    Keywords:  Academic; Advanced degree; Degrees; Faculty; Plastic surgery
  36. J Clin Hypertens (Greenwich). 2021 Mar 02.
      This review presents publication trends, characteristics, and quality of systematic reviews (SRs) of randomized controlled trials (RCTs) of antihypertensive drugs (AHTDs). Between 1985 and 2017, 1,173 SRs were published, and in the last 20 years, 10, 35, and 116 were published in the year 1996, 2006, and 2016, respectively. Angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers were the most common class of drugs studied. Fourteen percent of the SRs were prospectively registered/published protocol. Three-fourth of the SRs did not report a full search strategy, and 45% did not report a PRISMA or similar diagram. Of the 34 SRs published in the five high impact factor journals in the last 10 years, 15%, 21%, and 65% have unclear, low, and high risk of bias, respectively. There has been a steady increase in the publication of SRs of RCTs of AHTDs. However, adherence to standard methods of conduct and reporting continues to be low.
    Keywords:  antihypertensive agents; mapping review; risk of bias; systematic reviews
  37. Int J Environ Res Public Health. 2021 Feb 19. pii: 2050. [Epub ahead of print]18(4):
      In the present age, environmental pollution is multiplying due to various anthropogenic activities. Pollution from waste cooking oil is one of the main issues facing the current human population. Scientists and researchers are seriously concerned about the oils released from various activities, including the blockage of the urban drainage system and odor issues. In addition, cooking oil is known to be harmful and may have a carcinogenic effect. It was found that current research studies and publications are growing on these topics due to environmental problems. A bibliometric analysis of studies published from 2001 to 2021 on cooking oil degradation was carried out using the Scopus database. Primarily, this analysis identified the reliability of the topic for the present-day and explored the past and present progresses of publications on various aspects, including the contributing countries, journals and keywords co-occurrence. The links and interactions between the selected subjects (journals and keywords) were further visualised using the VOSviewer software. The analysis showed that the productivity of the publications is still developing, with the most contributing country being the United States, followed by China and India with 635, 359 and 320 publications, respectively. From a total of 1915 publications, 85 publications were published in the Journal of Agricultural and Food Chemistry. Meanwhile, the second and third of the most influential journals were Bioresource Technology and Industrial Crops and Products with 76 and 70 total publications, respectively. Most importantly, the co-occurrence of the author's keywords revealed "biodegradation", "bioremediation", "vegetable oil" and "Antarctic" as the popular topics in this study area, especially from 2011 to 2015. In conclusion, this bibliometric analysis on the degradation of cooking oil may serve as guide for future avenues of research in this area of research.
    Keywords:  Antarctic; biodegradation; bioremediation; cooking oil
  38. Sci Rep. 2021 Mar 04. 11(1): 5225
      Unicompartimental and total knee arthroplasty is one of the most successful and most performed operations worldwide. In the last years the number of primary knee arthroplasty increased constantly. The aim of this study is to analyze the rising numbers of primary knee arthroplasty and to see how it is used in Germany. In this retrospective study data, provided by the Federal Statistical Office of Germany from 2008 to 2018 was analyzed, using operation codes from the German procedure classification system and characteristics like age, sex and type of the prosthesis. We found a slight increase of unicompartimental and total knee arthroplasty over the investigated 10 years from 150.504 in 2008 up to 168.479 procedures in 2018, with a maximum of 169.334 in 2017. Most patients were female and over 65 years old. Interestingly, there was an obvious decrease of regular TKA in the year 2013, with a relevant impact on the total number of procedures. In the following years the number rised again reaching the former level in 2015 and is still increasing. The highest increase was found in partial knee arthroplasty, with a constant rise every year, starting with 7988 in 2008 up to 21.072 in 2018. In contrast, we found a relevant reduction of constrained prosthesis in primary TKA, whereas the number of semi-constrained prosthesis in primary TKA is again rising after a decrease in 2015. We found that the number of bicondylar TKA and especially UKA increased from 2008 to 2018. Regarding an aging population, we can expect a rising number for Primary knee arthroplasty and in consequence a rising number of revision arthroplasty in the future. This will be a challenging cost factor for the healthcare system in Germany.