bims-evares Biomed News
on Evaluation of research
Issue of 2020‒10‒04
forty-four papers selected by
Thomas Krichel
Open Library Society


  1. Infect Drug Resist. 2020 ;13 3195-3208
    Liu X, Wu X, Tang J, Zhang L, Jia X.
      Objective: Data visualization software were used to display and analyze the research status, hotspot and development trend of the antibiotic-resistance of Acinetobacter baumannii objectively and comprehensively, so as to provide guidance and reference for the research of the antibiotic-resistant Acinetobacter baumannii.Materials and Methods: The data of relevant publications on antibiotic-resistant Acinetobacter baumanii from 1991 to 2019 were retrieved from Web of Science (WOS) Core database. VOSviewer and CiteSpace software were used to conduct co-citation visualization network rendering and cluster analysis on the publications' years, authors, countries, institutions, keywords and citations.
    Results: A total of 3915 valid records on the study of antibiotic-resistant Acinetobacter baumanii were retrieved. The number of relevant publications was increasing year after year. The United States is the most influential country in the field, which works closely with other countries and publishes most of the papers. University of Sydney is the leading institution in this area. Bonomo Robert A publishes most of the papers. There are the highest number of publications in the research areas of antimicrobial agents and chemotherapy. "Nucleotide sequence" and "outbreak" were once the hotspots in this field, but recently "bacteriophage", "biofilm" and "colistin resistance" have become the research hotspots.
    Conclusion: Since 1991, the number of publications on antibiotic-resistant Acinetobacter baumannii has grown rapidly, and various countries and institutions have paid close attention to the problem of antibiotic resistance. Countries, institutions and researchers, which have strong influential power, collaborate with each other closely. The future research direction of antibiotic-resistant Acinetobacter baumannii should lie in the further breakthrough of antibacterial peptides, bacteriophage therapy, CRISPR system and various combined therapies.
    Keywords:  Acinetobacter baumannii; CiteSpace; antibiotic resistance; scientometric; visualized analysis
    DOI:  https://doi.org/10.2147/IDR.S264391
  2. J Neuroimmunol. 2020 Sep 08. pii: S0165-5728(20)30247-2. [Epub ahead of print]349 577379
    García-Fernández FJ, García-Fernández AE, Nava E, Del Pozo JSG, Ikuta I, Jordan J, Galindo MF.
      Natalizumab is being used in recurrent multiple sclerosis despite its history of market withdrawal due to lethal cases. We have carried out a bibliometric analysis of this drug from 1999 to February 2020 in order to assess the real impact of the use natalizumab with the goal to identify the key articles that sustain the current knowledge on the therapeutic possibilities of this compound. We have extracted from the Web of Science the top 100 most cited records (T100) and tabulated data on the journal, authors, publication year, number of citations, countries and institutions of publication, T100-records, citation density and citations per record of the works. The 100 most cited articles were selected from a total of 32,507 citations out of 2817 publications with an h-number of 74, 11.54 citations/publication, and a density of 1544.79 citations/year. Citations ranged from 63 of the paper placed in the 100th position (T100) to 1940 of the paper in the first position (T1). T2 was cited 888 times, and the difference in the number of citations between T1 and T2 was higher than that between T2 and T10. T1, T2 and T3 are clinical trials. When articles are arranged by institution and nationality having more than 10 T100 articles, biotechnology company Biogen and the USA, respectively, lead the ranking, but we also find that 8 out of 10 are academic European institutions. A co-authorship analysis reveals an intense collaborative activity between countries and institutions. We conclude that the clinical and academic communities have shown a sustained interest in natalizumab for the therapy of recurrent multiple sclerosis over the last 20 years.
    Keywords:  Bibliometric; Natalizumab; Top 100 cited articles
    DOI:  https://doi.org/10.1016/j.jneuroim.2020.577379
  3. Int J Oral Maxillofac Implants. 2020 Sep/Oct;35(5):35(5): 900-909
    Chiang HS, Tsai YC, Huang RY, Weng PW, Mau LP, Nguyen TT, Cochran DL, Sung CE, Chung CH, Shieh YS, Cheng WC.
      PURPOSE: Citation-based metrics, such as the H-classics method, have been used as an indicator to assess academic performance in the scientific community. However, information addressing issues regarding self-citation, citation half-life, and subject area of origin in implant dentistry is lacking. The purpose of this study was to investigate the citation characteristics of H-classics articles in implant dentistry throughout different time periods.MATERIALS AND METHODS: H-classics implant dentistry articles were searched and selected by applying the H-classics method from the Scopus database. Bibliometric analysis was conducted to evaluate the citation characteristics, including institutional and journal self-citation, citation half-life, and subject area of origin of identified H-classics articles.
    RESULTS: The International Journal of Oral & Maxillofacial Implants and Clinical Oral Implants Research are the leading journals contributing the majority of citations to the retrieved H-classics articles. Articles published in the United States cited the most H-classics articles. Journal self-citation was 12.41% on average, while institutional self-citation was approximately 7.81%. Citation half-life decreased significantly across time periods, with an average decreasing ratio of 43.95%. Research on Scope III, bioengineering interventions, had the most prominent distribution citation frequency in the subject area "Others."
    CONCLUSION: This study provides insightful views regarding citation characteristics of H-classics articles in implant dentistry (eg, interdisciplinary publications on bioengineering interventions) during the investigation periods, which may foster the translation of preclinical research into clinical applications in the future.
    DOI:  https://doi.org/10.11607/jomi.8129
  4. Front Psychol. 2020 ;11 1845
    Chriki S, Ellies-Oury MP, Fournier D, Liu J, Hocquette JF.
      Cultured meat is presented by its advocates as a good alternative for consumers who want to be more ethically minded but who do not wish to change their diet. This novel food has become an emerging topic in both the scientific field and the press media. From a bibliometric analysis of scientific publications and on a sociometric analysis of the mainstream press, the aim of this study was to identify potential differences between the scientific view and the public perception. This research analyzed the publications indexed by SCI-EXPANDED in the Web of Science Core Collection database owned by Clarivate Analytics, for scientific literature analysis, and indexed by the Factiva database, for the press media. A total of 327 scientific publications were analyzed according to year of publication and country and institution of origin, also including coauthorships, co-citations, and scientific fields' and journals' networks. A knowledge mapping using VOSviewer was used to study the literature in the field. Based on Factiva, 12,900 press articles dealing with artificial meat, mainly in English, have been found through public databases. The main conclusion is that cultured meat is mainly developing in the USA and the UK, with other countries, such as China, observing the trend for potential future applications. Scientific articles seemed initially to focus mainly on technical aspects of artificial meat and more recently on health value, consumer's acceptance, and sustainability. However, the potential environment-friendly effects of this novel food are more and more studied or described in scientific or press articles.
    Keywords:  Web of Science; bibliometrics; cultured meat; perception; press; public
    DOI:  https://doi.org/10.3389/fpsyg.2020.01845
  5. World Neurosurg. 2020 Sep 24. pii: S1878-8750(20)32107-0. [Epub ahead of print]
    Elarjani T, Almutairi OT, Alhussinan M, Alzhrani G, Alotaibi FE, Bafaquh M, Orz Y, Yamani M, Alturki AY.
      OBJECTIVE: Bibliometric analysis reflects the scientific recognition and influential performance of a published article within its field. Our aim is to identify and analyze the top 100 most-cited articles on cerebral vasospasm.METHOD: Title specific search was carried out using Scopus database. The top 100 cited articles including the keywords "Cerebral Vasospasm" AND "Vasospasm" were retrieved and stratified in a descending order: title, authors, institution, publishing journal, country of origin, year of publication, and topic of each manuscript were studied.
    RESULTS: The top 100 articles have an accumulative citation count of 20972, with 209 average citations per paper. Publication dates ranged from 1968 to 2012, with the most productive years ranged between 1998 and 2005. Clinical studies are the most frequent category followed by pathophysiology. The list is comprised of 7 clinical trials that received accumulative citations of 1525. The top cited article had received total of 2109 citations with 52.7 citations per year. The top 100 articles were published across 14 countries, with the majority originating from the USA. The lead research institution was the University of Alberta. The most utilized journal was the Journal of Neurosurgery.
    CONCLUSION: Bibliometric analysis has garnered major interests in recent years. It reveals the publication trends, knowledge evolution, and evidence based practice throughout the years. The current collection of highly cited publications may assist physicians in gaining a better understanding of cerebral vasospasm's nature and optimize their clinical practice.
    Keywords:  Bibliometric; Cerebral Vasospasms; Citation Analysis; Subarachnoid Hemorrhage
    DOI:  https://doi.org/10.1016/j.wneu.2020.09.099
  6. J Acute Med. 2019 Dec 01. 9(4): 153-160
    Chou YM, Lee CH.
      Background: Scientific publications and academic research are objective indicators that provide dynamic views of the evolution of emergency medicine (EM). This study is aimed to evaluate the academic contribution of Taiwan emergency departments (EDs) by analyzing scientific publications.Methods: This is an observational study and all publications between 2012 and 2017 were retrieved from the Scopus database. The EM journals were adopted from the 2016 Journal Citation Reports (JCR) category of EM. Three groups of publications were enrolled: (1) publications with first authors affiliated with Taiwan EDs in EM journals; (2) publications with first authors affiliated with Taiwan EDs in non-EM journals; (3) publications with first authors affiliated with Taiwan other than EDs in EM journals. Data regarding the name and category of the publishing journal, the publication year, the publication type, and the number of citations were collected for further analysis. The publication and category numbers were also merged with previous study to obtain a longer trend analysis from 1992.
    Results: A total of 291 publications affiliated with Taiwan EDs were published in EM journals and 697 publications in 275 non-EM journals. A total of 286 publications in EM journals affiliated with Taiwan but other than ED. The trend of publication numbers in all three groups and category numbers since 1992 were increasing (all p < 0.001). Publication numbers in non-EM journals increased the most and obtained the highest cited times. The 275 non-EM journals were classified into 69 categories. The leading five categories were Medicine, General & Internal, Multidisciplinary Sciences, Surgery, Infectious Diseases, Geriatrics & Gerontology.
    Conclusions: The importance of researches originating from Taiwan EDs has been increasingly recognized by both the global EM community and by other medical specialties during the past 25 years. The advancement of academic contribution by Taiwan EDs is evident from the perspectives of quantity and breadth.
    Keywords:  Journal Citation Reports; Scopus database; emergency medicine; scientific publications
    DOI:  https://doi.org/10.6705/j.jacme.201912_9(4).0001
  7. J Prosthet Dent. 2020 Sep 29. pii: S0022-3913(20)30461-3. [Epub ahead of print]
    Chen Y, Yeung AWK, Pow EHN, Tsoi JKH.
      STATEMENT OF PROBLEM: Lithium disilicate (LD) is a popular dental ceramic and has been a focus of dental research. Nevertheless, a quantified literature analysis focusing on the research of lithium disilicate is lacking.PURPOSE: The purpose of this bibliometric analysis was to review the progress of research into lithium disilicate in dentistry, including the identification of contributing researchers, organizations, countries or regions, journals, and the analysis of high-impact keywords and research trending.
    MATERIAL AND METHODS: The search was carried out within the topic field of the Web of Science (WoS) database, collecting publications related to LD from between 1996 and 2019. Metadata including the titles, abstracts, keywords, authors, affiliations, countries or regions, and references were extracted. Bibliometric indicators in terms of documents, authors, journals, and keywords were analyzed.
    RESULTS: Between 1996 and 2019, the dental research on LD trended upward. Scholars in the United States, Germany, Switzerland, and Brazil actively participated in the research on LD, and publications from the United States had the most citations. The Journal of Prosthetic Dentistry and Dental Materials were the major contributing journals. High-impact terms could be categorized into types of restorative material, types of prostheses, and properties or techniques of materials. Co-occurrence and relative normalized citation analysis of keywords highlighted several research interests, such as comparison studies between LD and zirconia, computer-aided design and computer-aided manufacturing (CAD-CAM) techniques, and the performance of complete coverage LD restorations.
    CONCLUSIONS: With the global upsurge in research on lithium disilicate, extensive collaborations and citations have been noted among authors, institutions, and countries or regions. Research hotspots include types of restorative material, types of prostheses, and properties or techniques of materials.
    DOI:  https://doi.org/10.1016/j.prosdent.2020.08.012
  8. Childs Nerv Syst. 2020 Sep 26.
    Kutluk MG, Danis A.
      BACKGROUND/OBJECTIVE: Childhood epilepsy is one of the disease groups with the highest disease burden in society. This study aimed to guide researchers for new studies by determining the most compelling studies and current issues through a bibliometric analysis of scientific outputs about childhood epilepsy between 1980 and 2018.METHODS: The literature review was conducted using the Web of Science (WoS) database. Epilepsy and status epilepticus were used as search keywords in WoS, and the search was performed only in the title section of the publications. Only publications in the research field of pediatrics were included in the study and were analyzed bibliometrically. Linear regression analysis was used to estimate the number of publications in the coming years.
    RESULTS: It was seen that the number of articles on pediatric epilepsy has been increasing with a linear trend. A total of 3424 publications were found. Of these publications, 2197 (64.2%) articles were analyzed bibliometrically. The top two most productive countries were the USA(654) and Italy (199). The first two most active institutions were The Hospital for Sick Children (40, 1.8%) and Tel Aviv University (38, 1.7%). The top three journals that published the most were Journal of Child Neurology (422, 19.2%), Pediatric Neurology (335, 15.2%), and Developmental Medicine and Child Neurology (201, 9.1%).
    CONCLUSION: In this bibliometric study on childhood epilepsies, a data summary of 2197 articles published between 1980 and 2018 is presented. We hope that this article will be a useful literature review and guide researchers working on pediatric epilepsy.
    Keywords:  Bibliometric analysis; Epilepsy; Pediatric; Status epilepticus; Trends
    DOI:  https://doi.org/10.1007/s00381-020-04897-9
  9. J Diabetes Res. 2020 ;2020 5767582
    Yang Y, Ma Y, Chen L, Liu Y, Zhang Y.
      Objective: The objective of this study was to analyze the 100 top-cited systematic reviews/meta-analyses on diabetic research.Methods: The Science Citation Index Expanded database was searched to identify top-cited studies on diabetic research up to March 4th, 2020. Studies were analyzed using the following characteristics: citation number, publication year, country and institution of origin, authorship, topics, and journals.
    Results: The 100 top-cited diabetic systematic reviews/meta-analyses were published in 43 different journals, with Diabetes Care having the highest numbers (n = 17), followed by The Journal of the American Medical Association (n = 14) and Lancet (n = 9). The majority of studies are published in the 2000s. The number of citations ranged from 2197 to 301. The highest number of contributions was from the USA, followed by England and Australia. The leading institution was Harvard University. The hot topic was a risk factor (n = 33), followed by comorbidity (n = 27).
    Conclusions: The 100 top-cited systematic reviews/meta-analyses on diabetic research identify impactful authors, journals, institutes, and countries. It will also provide the most important references to evidence-based medicine in diabetes and serve as a guide to the features of a citable paper in this field.
    DOI:  https://doi.org/10.1155/2020/5767582
  10. Int J Med Inform. 2020 Sep 19. pii: S1386-5056(19)31415-7. [Epub ahead of print]143 104274
    Higaki A, Uetani T, Ikeda S, Yamaguchi O.
      BACKGROUND: With the recent advances in computational science, machine-learning methods have been increasingly used in medical research. Because such projects usually require both a clinician and a computational data scientist, there is a need for interdisciplinary research collaboration. However, there has been no published analysis of research collaboration networks in cardiovascular medicine using machine intelligence.METHODS: Co-authorship network analysis was conducted on 2857 research articles published between 2009 and 2019. Bibliographic data were collected from the Web of Science, and the co-authorship networks were represented as undirected multigraphs. The network density, average degree, clustering coefficient, and number of communities were calculated, and the chronological changes were assessed. Thereafter, the leading authors were identified according to the centrality metrics. Finally, we investigated the significance of the characteristics of the co-authorship network in the largest component via a Monte Carlo simulation with the Barabasi-Albert model.
    RESULTS: The co-authorship network of the entire period consisted of 13,979 nodes and 68,668 weighted edges. A time-series analysis revealed a linear correlation between the number of nodes and the number of edges (R2 = 0.9937, p < 0.001). Additionally, the number of communities was linearly correlated with the number of nodes (R2 = 0.9788, p < 0.001). The average shortest path increased by a greater degree than the logarithm of the number of nodes, indicating the scale-free structure of the network. We identified D. Berman as the most central author with regard to the degree centrality and closeness centrality. S. Neubauer was the top-ranking author with regard to the betweenness centrality. Among the 22 authors who were ranked in the top 10 for any centrality, 14 authors (63.6%) had a medical degree (medical doctor, MD). The remaining eight non-MD researchers had a PhD in computational science-related fields. The number of communities detected in the Barabasi-Albert model simulation was similar to that for the largest component of the real network (6.21 ± 0.07 vs. 6, p = 0.096).
    CONCLUSIONS: A co-authorship network analysis revealed a structure of collaboration networks in the application of machine learning in the field of cardiovascular disease, which can be useful for planning future scientific collaboration.
    Keywords:  Cardiovascular research; Co-authorship network analysis; Machine learning; Natural language processing; Social network analysis
    DOI:  https://doi.org/10.1016/j.ijmedinf.2020.104274
  11. Healthcare (Basel). 2020 Sep 25. pii: E367. [Epub ahead of print]8(4):
    Kim Y, Kim JE, Lee SH, Yoon DY, Bae JS.
      This study used Altmetric analysis to rank neurological articles and assessed the implications in relation to the social recognition of neurology and neurological disorders. An Altmetric Explorer search was conducted on 25 May 2018 for articles published in the 91 journals included in the 2015 InCites™ Journal Citation Report®. We identified and analyzed the 100 articles with the highest Altmetric Attention Scores (AASs). A major proportion of the social impact (high AASs) was focused on neurodegenerative disorders such as dementia and neurodegenerative disorders. About half of the high-ranking articles provided academic information such as disease information (29 articles, 29%), new or advanced treatments (17%), and side effects of treatment (8%). The journal with largest number of top 100 articles was the New England Journal of Medicine (29 articles). Some of the data gathered via altmetrics can change a field of study, the public's health, or a larger society. This is the first report on the impact of academic articles in neurological disorder on the general public living in our altered information society.
    Keywords:  attention; neurodegenerative diseases; neurology; public health informatics; social networking
    DOI:  https://doi.org/10.3390/healthcare8040367
  12. Ann Med Surg (Lond). 2020 Nov;59 76-80
    Rhatomy S, Utomo DN, Suroto H, Mahyudin F.
      Purpose: This study aimed to determine the number of posterior cruciate ligament (PCL) publications performed in Asian countries and to identify factors associated with research output in this region.Materials and methods: Searches of existing academic journal articles were performed using PubMed, Google Scholar, and the Cochrane Library from January 1, 2009 until December 31, 2019.
    Results: A total of 265 articles were published in the last 10 years in Asian countries, with an increase in publications after 2010 and an average of 26 articles every year. More than half (70%) of the articles were published in journals with an impact factor (IF) ≥1. The majority of the publications were cohort studies (27%), followed by case reports (16%), systematic reviews/meta-analyses (2.6%), laboratory studies (1.8%), and case-control studies (1.5%). South Korea and China had the most PCL publications, and most authors were from South Korea.
    Conclusion: The PCL research output in Asia is low in quantity but high in quality publications, and the majority of publications come from South Korea, China and Japan, with most being cohort studies and case reports.
    Keywords:  Asian countries; PCL; Posterior cruciate ligament; Research output
    DOI:  https://doi.org/10.1016/j.amsu.2020.09.006
  13. J Clin Exp Dent. 2020 Sep;12(9): e857-e863
    Bhalla VK, Chockattu SJ.
      Background: Journal of Clinical and Experimental Dentistry (J Clin Exp Dent; JCED) is an English language journal published by the Spanish Society of Oral Surgery, and has been online since 2009. It is indexed in PubMed Central and Scopus since 2012, with monthly publications since 2016. The purpose of this article was to review and analyse the publications in this journal since its inception, over a period of 11 years (2009-2019).Material and Methods: This paper assessed the number, type and subjects of the articles published in the journal over 11 years. The institutions of the first authors, number of PubMed citations and the Hirsch (h5) index was assessed and analysed.
    Results: The manuscripts published in JCED have gradually increased over the years, with Original research articles accounting for the bulk of contributions. The journal publishes articles mainly from the subjects of Oral Pathology and Operative Dentistry and Endodontics. Articles published in JCED are indexed in PubMed Central (since 2012), Scopus, DOI system, and Google Scholar. A country-wise mapping of the (first) author's institutions revealed significant contributions from researchers from all over the world. With an h5 index of 26, the journal was ranked among the top six multispeciality journals. The most cited articles were the literature reviews on common oral lesions (recurrent apthous stomatitis and candidiasis).
    Conclusions: The journal has contributed to the growth of scientific literature pertaining to subjects from all the fields of dentistry. Over the past 11 years, JCED has served as a platform for large number of manuscripts in all the disciples of dentistry, from researches all over the world. Key words:Publication trends, Journal of Clinical and Experimental Dentistry, Bibliometrics.
    DOI:  https://doi.org/10.4317/jced.56640
  14. Environ Sci Pollut Res Int. 2020 Sep 29.
    Sun L, Wu L, Qi P.
      The relationship between industrial structure and carbon emissions has been widely identified as a critical research topic by international organizations and academics. Using bibliometrics analysis, this study aimed at dissecting the global characteristics and trends of research on industrial structure and carbon emissions. Based on the 806 documents from 2004 to 2019 in Web of Science, this work was implemented from four aspects, including basic characteristics analysis, country/territory and institution analysis, category and journal analysis, and reference and keyword analysis. The results of this study showed rapid growth trends of research on industrial structure and carbon emissions from 2015 to 2019. The collaborations among countries and institutions were extensive worldwide with China, the USA, and the UK as the main participants. Furthermore, the corresponding research topics, research priorities, and research paths were summarized according to the references co-citation analysis and keywords cluster analysis, which from the perspective of the correlation between different types of industry with carbon emissions. Finally, the timezone view of the top 100 keywords indicated that the emerging trends in the research on industrial structure and carbon emissions were regional analysis, industrialization, and environmental efficiency, and prediction of carbon emissions peak and the spatial distribution in different types of industries were the hotspots in recent years. The findings provide a better understanding of global characteristics and trends that have emerged in this field, which can also offer reference for future research.
    Keywords:  Bibliometrics analysis; Carbon emissions; Global characteristics; Industrial structure; Mapping knowledge domain; Research hotspots
    DOI:  https://doi.org/10.1007/s11356-020-10915-9
  15. Environ Health Prev Med. 2020 Oct 02. 25(1): 57
    Li J, Zhu Y, Feng J, Meng W, Begma K, Zhu G, Wang X, Wu D, Shi F, Wang S.
      BACKGROUND: At the end of 2019, the outbreak of coronavirus disease 2019 (COVID-19) severely damaged and endangered people's lives. The public health emergency management system in China has played an essential role in handling the response to the outbreak, which has been appreciated by the World Health Organization and some countries. Hence, it is necessary to conduct an overall analysis of the development of the health emergency management system in China. This can provide a reference for scholars to aid in understanding the current situation and to reveal new research topics.METHODS: We collected 2247 international articles from the Web of Science database and 959 Chinese articles from the China National Knowledge Infrastructure database. Bibliometric and mapping knowledge domain analysis methods were used in this study for temporal distribution analysis, cooperation network analysis, and co-word network analysis.
    RESULTS: The first international article in this field was published in 1991, while the first Chinese article was published in 2005. The research institutions producing these studies mainly existed in universities and health organizations. Developed countries and European countries published the most articles overall, while eastern China published the most articles within China. There were 52 burst words for international articles published from 1999-2018 and 18 burst words for Chinese articles published from 2003-2018. International top-ranked articles according to the number of citations appeared in 2005, 2007, 2009, 2014, 2015, and 2016, while the corresponding Chinese articles appeared in 2003, 2004, 2009, and 2011.
    CONCLUSIONS: There are differences in the regional and economic distribution of international and Chinese cooperation networks. International research is often related to timely issues mainly by focusing on emergency preparedness and monitoring of public health events, while China has focused on public health emergencies and their disposition. International research began on terrorism and bioterrorism, followed by disaster planning and emergency preparedness, epidemics, and infectious diseases. China considered severe acute respiratory syndrome as the starting research background and the legal system construction as the research starting point, which was followed by the mechanism, structure, system, and training abroad for public health emergency management.
    Keywords:  Emergency management; Knowledge domains; Public health
    DOI:  https://doi.org/10.1186/s12199-020-00896-z
  16. BMC Anesthesiol. 2020 Sep 28. 20(1): 247
    Kanmounye US, Tochie JN, Mbonda A, Wafo CK, Daya L, Atem TH, Nyalundja AD, Eyaman DC.
      BACKGROUND: Research is an essential component of Anesthesia, and the contributions of researchers and institutions can be appreciated from the analysis of scholarly outputs. Such analyses help identify major contributors and trends in publication. Little is known about the state of Anesthesia and Critical Care Medicine (A.C.C.M.) research in Africa. We aimed to describe African A.C.C.M. research's current landscape by determining its productivity per country and point towards possible ideas for improvement.METHODS: The authors searched PubMed, Embase, Web of Science, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) from inception to May 4, 2020, for articles on or about A.C.C.M. in Africa. Studies were selected based on their titles and abstracts. Rayyan software was later on used for data management in the review selection process. Then, the full-text of eligible articles were screened. Data were extracted, and the number of articles per physician anesthesia providers and provider density were calculated. Kruskal Wallis test and Spearman's correlation were used, and a P-value < 0.05 was considered statistically significant.
    RESULTS: Of the 4690 articles, only 886 (18.9%) were included in the analysis. The articles were published between 1946 and 2020 in 278 target journals. 55 (6.2%) articles were published in the South African Journal of Surgery, 51 (5.8%) in Anesthesia and Analgesia, and 46 (5.2%) in Anaesthesia. 291 (32.8%) studies were cross-sectional. 195 (22.0%) first authors were from Nigeria, 118 (13.3%) from South Africa, and 88 (9.9%) from the U.S.A. Malawi (1.67), Togo (1.06), and Sierra Leone (1.00) had the highest number of articles per provider. Whereas Ethiopia (580.00), Nigeria (336.21), and Malawi (333.33) had the highest number of articles per provider density.
    CONCLUSION: We identified the most and least productive African countries in A.C.C.M. research and a low-quality hierarchy of evidence in these publications. Hence, the study's findings may aid in driving the A.C.C.M. research agenda and capacity building in Africa.
    Keywords:  Africa; Anesthesia; Bibliometrics; Global anesthesia; Research
    DOI:  https://doi.org/10.1186/s12871-020-01167-8
  17. Cardiovasc Res. 2020 Oct 01. 116(12): e165-e168
    Sheikh AM, Small HY, Antoniades C, Guzik TJ.
      
    Keywords:  Altmetric; Cardiovascular; Citation; Impact factor; Research
    DOI:  https://doi.org/10.1093/cvr/cvaa262
  18. Emergencias. 2020 Sep;32(5): 305-306
    Miró Ò.
      
  19. J Acute Med. 2019 Sep 01. 9(3): 83-109
    Lin CH.
      This study aimed to examine scientific publications that were related to disaster medicine and were authored by emergency medicine physicians in Taiwan. This descriptive study utilized the electronic databases of PubMed, Scopus, and Web of Science. Academic works that were published between January 1, 1999, and December 31, 2018, were collected for review and analysis. Of the 53 articles included in the final analysis,40 (75.5%) were original research, 3 (5.7%) were reviews, 1 (1.9%) was a brief report, and 9 (17.0%) were perspectives. The top 5 themes were disaster response systems (17, 32.1%), endemic diseases (11, 20.8%), emergency department (ED) overcrowding (10, 18.9%), earthquakes (10, 18.9%), and ED administration (9, 17.0%). Sixteen (30.2%) articles involved international collaborations. The median, interquartile range and range of the numbers of citations of the articles were 3, 1-11, and 0-65, respectively. Twenty-four (45.3%) articles were related to specific incidents: the Chi-Chi earthquake in 1999 (n = 5), the Singapore airline crash in 2000 (n = 1), Typhoon Nari in 2001 (n = 1), the outbreak of severe acute respiratory syndrome in 2003 (n = 7), Typhoon Morakot in 2009 (n = 1), the color party explosion in Formosa Fun Coast Park in 2015 (n = 4), and the Tainan earthquake in 2016 (n = 5). Regarding the study methods, 19 (35.8%) articles were quantitative studies; 10 (18.9%) were qualitative or semiqualitative studies; 8 (15.1%) used questionnaire surveys; 3 (5.7%) were literature reviews; 3 (5.7%) used computer simulations; and 10 (18.9%) were descriptive/narrative or other types of studies. Though the number of academic publications related to disaster medicine from the EDs in Taiwan is relatively limited, the quality and diversity of research seem promising. The research environment and education programs on disaster medicine in Taiwan deserve thoughtful consideration.
    Keywords:  Taiwan; disaster; disaster medicine; emergency medicine; review
    DOI:  https://doi.org/10.6705/j.jacme.201909_9(3).0002
  20. BMC Infect Dis. 2020 Sep 29. 20(1): 715
    Liu E, Iwelunmor J, Gabagaya G, Anyasi H, Leyton A, Goraleski KA, Wei S, Del Barrio MO, Olaleye A, Launois P, Tucker JD.
      BACKGROUND: Women are under-represented in many mid-career infectious diseases research fellowships, including a TDR fellowship for low- and middle-income country (LMIC) researchers. TDR solicited creative ideas as part of a challenge contest to increase the number of women fellowship applicants. The purpose of this study is to examine themes from submitted ideas and the impact of implementing the top three ideas on the number of women applicants.METHODS: We solicited ideas for modifying the TDR fellowship using a crowdsourcing challenge. Then we used a mixed methods approach to evaluate texts submitted in response to the challenge. The qualitative analysis identified themes from eligible submissions. The quantitative analysis examined the mean score (1-10 scale) assigned to submitted ideas and also the number of eligible women applicants before (2014-7) and after (2018) implementing the top three ideas.
    RESULTS: We received 311 ideas on improving women's participation in this fellowship from 63 countries. Among all ideas, 282 (91%) were from women and 286 (92%) were from low- and middle-income countries (LMICs). Thirty-three (17%) ideas received an overall mean score of 7.0 or greater. The top three ideas included enhanced social media communication targeting women, improving career mentorship, and creating a nomination system to nudge women applicants. These ideas were implemented as part of the 2018 fellowship application cycle. The number of eligible women applicants increased from 11 in 2016 to 48 in 2018. The number of eligible men applicants increased from 55 in 2016 to 114 in 2018. Women represent 44% (8/18) of the 2018 cohort.
    CONCLUSION: This suggests that the challenge contest resulted in strong participation from women in LMICs. The three top ideas likely contributed to a greater number of women applicants to this mid-career fellowship. Further ways of enhancing women's participation in global health training are needed.
    Keywords:  Challenge contest; Fellowship; Training; WHO
    DOI:  https://doi.org/10.1186/s12879-020-05433-5
  21. Medicines (Basel). 2020 Sep 29. pii: E62. [Epub ahead of print]7(10):
    Teschke R, Danan G.
      Background: A large number of idiosyncratic drug induced liver injury (iDILI) and herb induced liver injury(HILI) cases of variable quality has been published but some are a matter of concern if the cases were not evaluated for causality using a robust causality assessment method (CAM) such as RUCAM (Roussel Uclaf Causality Assessment Method) as diagnostiinjuryc algorithm. The purpose of this analysis was to evaluate the worldwide use of RUCAM in iDILI and HILI cases. Methods: The PubMed database (1993-30 June 2020) was searched for articles by using the following key terms: Roussel Uclaf Causality Assessment Method; RUCAM; Idiosyncratic drug induced liver injury; iDILI; Herb induced liver injury; HILI. Results: Considering reports published worldwide since 1993, our analysis showed the use of RUCAM for causality assessment in 95,885 cases of liver injury including 81,856 cases of idiosyncratic DILI and 14,029 cases of HILI. Among the top countries providing RUCAM based DILI cases were, in decreasing order, China, the US, Germany, Korea, and Italy, with China, Korea, Germany, India, and the US as the top countries for HILI. Conclusion: Since 1993 RUCAM is certainly the most widely used method to assess causality in IDILI and HILI. This should encourage practitioner, experts, and regulatory agencies to use it in order to reinforce their diagnosis and to take sound decisions.
    Keywords:  DILI; HILI; RUCAM; Roussel Uclaf Causality Assessment Method; diagnostic algorithm; herb induced liver injury; iDILI; iDrug induced liver injury
    DOI:  https://doi.org/10.3390/medicines7100062
  22. PLoS One. 2020 ;15(10): e0239598
    Hardwicke TE, Goodman SN.
      Scientific claims in biomedical research are typically derived from statistical analyses. However, misuse or misunderstanding of statistical procedures and results permeate the biomedical literature, affecting the validity of those claims. One approach journals have taken to address this issue is to enlist expert statistical reviewers. How many journals do this, how statistical review is incorporated, and how its value is perceived by editors is of interest. Here we report an expanded version of a survey conducted more than 20 years ago by Goodman and colleagues (1998) with the intention of characterizing contemporary statistical review policies at leading biomedical journals. We received eligible responses from 107 of 364 (28%) journals surveyed, across 57 fields, mostly from editors in chief. 34% (36/107) rarely or never use specialized statistical review, 34% (36/107) used it for 10-50% of their articles and 23% used it for all articles. These numbers have changed little since 1998 in spite of dramatically increased concern about research validity. The vast majority of editors regarded statistical review as having substantial incremental value beyond regular peer review and expressed comparatively little concern about the potential increase in reviewing time, cost, and difficulty identifying suitable statistical reviewers. Improved statistical education of researchers and different ways of employing statistical expertise are needed. Several proposals are discussed.
    DOI:  https://doi.org/10.1371/journal.pone.0239598
  23. Scientometrics. 2020 Sep 21. 1-36
    Martín-Martín A, Thelwall M, Orduna-Malea E, Delgado López-Cózar E.
      New sources of citation data have recently become available, such as Microsoft Academic, Dimensions, and the OpenCitations Index of CrossRef open DOI-to-DOI citations (COCI). Although these have been compared to the Web of Science Core Collection (WoS), Scopus, or Google Scholar, there is no systematic evidence of their differences across subject categories. In response, this paper investigates 3,073,351 citations found by these six data sources to 2,515 English-language highly-cited documents published in 2006 from 252 subject categories, expanding and updating the largest previous study. Google Scholar found 88% of all citations, many of which were not found by the other sources, and nearly all citations found by the remaining sources (89-94%). A similar pattern held within most subject categories. Microsoft Academic is the second largest overall (60% of all citations), including 82% of Scopus citations and 86% of WoS citations. In most categories, Microsoft Academic found more citations than Scopus and WoS (182 and 223 subject categories, respectively), but had coverage gaps in some areas, such as Physics and some Humanities categories. After Scopus, Dimensions is fourth largest (54% of all citations), including 84% of Scopus citations and 88% of WoS citations. It found more citations than Scopus in 36 categories, more than WoS in 185, and displays some coverage gaps, especially in the Humanities. Following WoS, COCI is the smallest, with 28% of all citations. Google Scholar is still the most comprehensive source. In many subject categories Microsoft Academic and Dimensions are good alternatives to Scopus and WoS in terms of coverage.
    Keywords:  Bibliographic databases; Bibliometrics; COCI; Citation analysis; Citations; Coverage; CrossRef; Dimensions; Google Scholar; Literature reviews; Microsoft Academic; OpenCitations; Scopus; Web of Science
    DOI:  https://doi.org/10.1007/s11192-020-03690-4
  24. BMJ Evid Based Med. 2020 Sep 30. pii: bmjebm-2020-111499. [Epub ahead of print]
    Yang S, Li A, Eshaghpour A, Ivanisevic S, Salopek A, Eikelboom J, Crowther M.
      Since the initial description of the SARS-CoV-2 outbreak and its declaration as a worldwide pandemic, the number of publications on the novel virus has increased rapidly. We studied the trends and quality of evidence in early SARS-CoV-2 publications. A comprehensive search of MEDLINE and EMBASE was performed for papers published between 1 January 2020 and 21 April 2020. Two reviewers independently screened titles and abstracts and subsequently full texts for eligibility in this systematic review. The search yielded 2504 citations published between January and February 2020 or an unspecified date, 109 of which remained for extraction after screening. Data extracted included study design, year of publication, country of basis, journal of publication, impact factor of publishing journal, study sample size, number of citations and topic of investigation. Study design-specific critical appraisal tools were used to evaluate the scientific rigour of all included papers: the Joanna Briggs Institute checklist was used for case series, Scale for the Assessment of Narrative Review Articles scale for narrative reviews, Newcastle-Ottawa scale for cohort studies and AMSTAR 2 for systematic reviews. The overall quality of the literature was low-moderate. Of 541 papers that reported clinical characteristics, 295 were commentaries/expert opinions and 36 were case reports. There were no randomised clinical trials, 45 case series studies, 58 narrative reviews, 1 cohort study and 5 systematic reviews. We encourage clinicians to be attentive to these findings when utilising early SARS-CoV-2 evidence in their practices.
    Keywords:  evidence-based practice
    DOI:  https://doi.org/10.1136/bmjebm-2020-111499
  25. J Am Coll Radiol. 2020 Sep 29. pii: S1546-1440(20)30962-5. [Epub ahead of print]
    Kennedy J, Perchik JD, Porter KK.
      PURPOSE: The ACR has established that diversity and inclusion are central to its mission of excellence in the radiologic professions; therefore, radiologists have a responsibility to serve the imaging needs of the transgender community. To understand radiologists' current knowledge of transgender topics, the authors performed a systematic review of publications from radiology journals.METHODS: A lexicon of 14 transgender-related terms was created and expanded through a PubMed keyword search. From the 129 journals from the radiology, nuclear medicine, and medical imaging category of Journal Citation Reports, 106 journals met the inclusion criteria, including English translation and Scopus data for the study period. Using the Scopus advanced search feature, articles with titles, abstracts, Medical Subject Headings terms, or keywords including 1 of 14 transgender terms were identified and analyzed.
    RESULTS: Of the more than 200,000 articles published by the 106 journals from January 2008 to July 2019, 29 relevant articles were identified. Only 14 of the 106 journals published any transgender-related topics. The volume of articles has increased over time. The largest proportion of articles was published under the "general radiology" subsection, with the majority of these being editorials (6 of 10). Most of the original research was published under "neuroradiology" (7 of 13). Use of nonpreferred language, such as "transsexual" and "natal sex" was present through 2019.
    CONCLUSIONS: Publication on transgender-related topics was uncommon among radiology journals. It is important to encourage further research and publication on transgender topics, as well as use of respectful, accepted language in radiology journals.
    Keywords:  Diversity; gender identity; health care disparities; inclusion; transition
    DOI:  https://doi.org/10.1016/j.jacr.2020.09.019
  26. Front Public Health. 2020 ;8 554247
    Gao Y, Yang K, Liu M, Chen Y, Shi S, Yang F, Tian J.
      Background: Research collaboration of registered clinical trials for Coronavirus Disease 2019 (COVID-19) remains unclear. This study aimed to analyze research collaboration and distribution of outcome measures in registered interventional clinical trials (ICTs) of COVID-19 conducted in China. Methods: The International Clinical Trials Registry Platform, China Clinical Trials Registry, and Clinicaltrials.gov were searched to obtain COVID-19-registered ICTs up to May 25, 2020. Excel 2016 was used to perform a descriptive statistical analysis of the extracted information. VOSviewer 1.6.14 software was used to generate network maps for provinces and institutions and create density maps for outcomes. Results: A total of 390 ICTs were included, and the number of daily registrations fluctuated greatly. From 29 provinces in China, 430 institutions contributed to the registration of ICTs. The top three productive provinces were Hubei (160/390, 41.03%), Shanghai (60/390, 15.38%), and Beijing (59/390, 15.13%). The top three productive institutions were Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (30/390, 7.69%), Zhongnan Hospital of Wuhan University (18/390, 4.62%), and Wuhan Jinyintan Hospital (18/390, 4.62%). Collaborations between provinces and institutions were not close enough. There were many interventions, but many trials did not provide specific drugs and their dosage and treatment duration. The most frequently used primary outcome was Chest/lung CT (53/390, 13.59%), and the most frequently used secondary outcome was hospital stay (33/390, 8.46%). There was a large difference in the number of outcomes, the expression of some outcomes was not standardized, the measurement time and tools for some outcomes were not clear, and there was a lack of special outcomes for trials of traditional Chinese medicine. Conclusions: Although there were some collaborations between provinces and institutions of the current COVID-19 ICT protocols in China, cooperation between regions should be further strengthened. The identified deficiencies in interventions and outcome measures should be given more attention by future researchers of COVID-19.
    Keywords:  COVID-19; SARS-CoV-2; clinical trials; outcome measures; protocol; research collaboration
    DOI:  https://doi.org/10.3389/fpubh.2020.554247
  27. Int J Disaster Risk Reduct. 2020 Dec;51 101877
    Zhang X, Zhong Q, Zhang R, Zhang M.
      People-Centered Early Warning Systems (PCEWSs) is thought to be low-cost but effective, however, existing studies fail to discuss the basic characteristics of PCEWSs, how a PCEWSs should be built, and the extensible applications of PCEWSs. This study aims for making a significant contribution to the literature through the analysis of the PCEWSs trajectory of and fundamental shifts in policy pertaining to PCEWSs in the disaster domain in China. By using bibliometric analysis of policy documents, this study presents a comprehensive review of China's PCEWS policy system from 1977 to March 2020, which focuses on various types of disasters. The characteristics of policies and the contributing factors of the policy changes in each of the four phases are discussed in depth. Four main tendencies of PCEWSs are identified. This study provides a quantitative foundation for understanding the dynamic policy changes in China's PCEWSs and certain experience includes the disaster characteristics that PCEWSs are suitable to get involved, the orientation that experience and technology should be combined and multi agent participation which calls for more emphasis may serve as a basis for exploring the potential pathways to the effective PCWSs in other countries and regions.
    Keywords:  Bibliometric analysis; Participation of people; People-centered early warning systems; Policy documents
    DOI:  https://doi.org/10.1016/j.ijdrr.2020.101877
  28. J Gastrointest Surg. 2020 Oct 02.
    Fu W, Liang X, Wei F, Cao J, Chen W, Mao Y, Yu T.
      
    Keywords:  Bibliometric analysis; Incidental gallbladder cancer; Research hotspots; Scientific cooperation
    DOI:  https://doi.org/10.1007/s11605-020-04785-2
  29. Scientometrics. 2020 Sep 21. 1-32
    Haghani M, Bliemer MCJ.
      During the current century, each major coronavirus outbreak has triggered a quick and immediate surge of academic publications on its respective topic. The spike in research publications following the 2019 Novel Coronavirus (Covid-19) outbreak, however, has been like no other. The global crisis caused by the Covid-19 pandemic has mobilised scientific efforts at an unprecedented scale. In less than 5 months, more than 12,000 research items and in less than seven months, more than 30,000 items were indexed, while it is projected that the number could exceed 80,000 by the end of 2020, should the current trend continues. With the health crisis affecting all aspects of life, research on Covid-19 seems to have become a focal point of interest across many academic disciplines. Here, scientometric aspects of the Covid-19 literature are analysed and contrasted with those of the two previous major coronavirus diseases, i.e., Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). The focus is on the co-occurrence of key-terms, bibliographic coupling and citation relations of journals and collaborations between countries. Interesting recurring patterns across all three literatures were discovered. All three outbreaks have commonly generated three distinct cohorts of studies: (i) studies linked to public health response and epidemic control, (ii) studies on chemical constitution of the virus; and (iii) studies related to treatment, vaccine and clinical care. While studies affiliated with category (i) seem to have been relatively earliest to emerge, they have overall received relatively smaller number of citations compared to publications the two other categories. Covid-19 studies seem to have been disseminated across a broader variety of journals and across a more diverse range of subject areas. Clear links are observed between the geographical origins of each outbreak as well as the local geographical severity of each outbreak and the magnitude of research originated from regions. Covid-19 studies also display the involvement of authors from a broader variety of countries compared to SARS and MERS. Considering the speed at which the Covid-19-related literature is accumulating, an interesting dimension that warrants further exploration could be to assess if the quality and rigour of these publications have been affected.
    Keywords:  Bibliometrics; Coronaviruses; Research synthesis; Scientometrics; Viral respiratory diseases
    DOI:  https://doi.org/10.1007/s11192-020-03706-z
  30. J Biomed Semantics. 2020 Sep 29. 11(1): 12
    Wolff P, Ríos S, Clavijo D, Graña M, Carrasco M.
      BACKGROUND: Medical knowledge is accumulated in scientific research papers along time. In order to exploit this knowledge by automated systems, there is a growing interest in developing text mining methodologies to extract, structure, and analyze in the shortest time possible the knowledge encoded in the large volume of medical literature. In this paper, we use the Latent Dirichlet Allocation approach to analyze the correlation between funding efforts and actually published research results in order to provide the policy makers with a systematic and rigorous tool to assess the efficiency of funding programs in the medical area.RESULTS: We have tested our methodology in the Revista Médica de Chile, years 2012-2015. 50 relevant semantic topics were identified within 643 medical scientific research papers. Relationships between the identified semantic topics were uncovered using visualization methods. We have also been able to analyze the funding patterns of scientific research underlying these publications. We found that only 29% of the publications declare funding sources, and we identified five topic clusters that concentrate 86% of the declared funds.
    CONCLUSIONS: Our methodology allows analyzing and interpreting the current state of medical research at a national level. The funding source analysis may be useful at the policy making level in order to assess the impact of actual funding policies, and to design new policies.
    Keywords:  Data science; Healthcare management; Latent Dirichlet allocation; Machine learning; Strategy
    DOI:  https://doi.org/10.1186/s13326-020-00226-w
  31. Trials. 2020 Oct 01. 21(1): 824
    Lombard N, Gasmi A, Sulpice L, Boudjema K, Naudet F, Bergeat D.
      OBJECTIVE: To describe surgical journals' position statements on data-sharing policies (primary objective) and to describe key features of their research transparency promotion.METHODS: Only "SURGICAL" journals with an impact factor higher than 2 (Web of Science) were eligible for the study. They were included, if there were explicit instructions for clinical trial publication in the official instructions for authors (OIA) or if they had published randomised controlled trial (RCT) between 1 January 2016 and 31 December 2018. The primary outcome was the existence of a data-sharing policy included in the instructions for authors. Data-sharing policies were grouped into 3 categories, inclusion of data-sharing policy mandatory, optional, or not available. Details on research transparency promotion were also collected, namely the existence of a "prospective registration of clinical trials requirement policy", a conflict of interests (COIs) disclosure requirement, and a specific reference to reporting guidelines, such as CONSORT for RCT.
    RESULTS: Among the 87 surgical journals identified, 82 were included in the study: 67 (82%) had explicit instructions for RCT and the remaining 15 (18%) had published at least one RCT. The median impact factor was 2.98 [IQR = 2.48-3.77], and in 2016 and 2017, the journals published a median of 11.5 RCT [IQR = 5-20.75]. The OIA of four journals (5%) stated that the inclusion of a data-sharing statement was mandatory, optional in 45% (n = 37), and not included in 50% (n = 41). No association was found between journal characteristics and the existence of data-sharing policies (mandatory or optional). A "prospective registration of clinical trials requirement" was associated with International Committee of Medical Journal Editors (ICMJE) allusion or affiliation and higher impact factors. Journals with specific RCT instructions in their OIA and journals referenced on the ICMJE website more frequently mandated the use of CONSORT guidelines.
    CONCLUSION: Research transparency promotion is still limited in surgical journals. Standardisation of journal requirements according to ICMJE guidelines could be a first step forward for research transparency promotion in surgery.
    Keywords:  CONSORT statement; Conflict of interest; Data sharing; Randomised controlled trial
    DOI:  https://doi.org/10.1186/s13063-020-04756-7
  32. Rev Med Inst Mex Seguro Soc. 2019 Dec 30. 57(6): 334-336
    Rivas-Ruiz R.
      National medical journals are important because they focus on local clinical problems, peer communication, and fostering critical reading among healthcare workers. The actors involved in the development of the journals must fulfill their purposes to improve the quality of the publications of the national journals and contribute to improve the quality of care.
    Keywords:  Journal Article; Journal Impact Factor; Peer Review, Research; Research; Scholarly Communication
  33. Int J Environ Res Public Health. 2020 Sep 27. pii: E7077. [Epub ahead of print]17(19):
    Liu L, Qu J, Maraseni TN, Niu Y, Zeng J, Zhang L, Xu L.
      The household sector, which plays a critical role in emission reduction, is a main source of greenhouse gas (GHG) emissions. Although numerous academic journals have published papers on household CO2 emissions (HCEs), great challenges remain in research on assessments, determinants, and further research prospects. This work reviews and projects HCEs using a bibliometric analysis and a systematic review based on the data from the Web of Science (WOS) platform from 1991 to 2020. Over the last 30 years, there has been a rapid and active trend of research on HCEs. We find that (1) the scale of the bibliometric analysis shows that research on HCEs is interdisciplinary and must consider overall cognition of the environment, the economy, society, and technology. It also needs to strengthen cooperation between different countries/territories to emphasize the quality and influence of papers on HCEs. (2) A review of previous literature shows that research on HCEs mainly focuses on the research object, mainstream assessments, and influencing factors. The following six main aspects impact HCEs: demographic, income, social, technological, policy, and natural factors. (3) The research discussion suggests that more micro-level research needs to be conducted, such as research on the city level and the individual level, which is important for sustainable development and low consumption. A comparative analysis of the differences in HCEs is a future research direction. Additionally, localized carbon emission reduction measures need to be implemented.
    Keywords:  bibliometric; household CO2 emissions; perspective; review
    DOI:  https://doi.org/10.3390/ijerph17197077
  34. J Investig Med. 2020 Oct 01. pii: jim-2020-001481. [Epub ahead of print]
    Dhamanaskar R, Merz JF.
      The prevalence of randomized controlled trials (RCTs) performed without fully informed prospective consent from subjects is unknown. We performed this study to estimate the prevalence of high-impact RCTs performed without informed consent from all subjects and examine whether such trials are becoming more prevalent. We performed a systematic review of English-language RCTs published from 2014 through 2018 identified in Scopus and sorted to identify the top 100 most highly cited RCTs each year. Text search of title and abstract included terms randomized controlled or clinical trial and spelling variants thereof, and excluded metaanalyses and systematic reviews. We independently identified the most highly cited RCTs based on predefined criteria and negotiated to agreement, then independently performed keyword searches, read, abstracted and coded information regarding informed consent from each paper and again negotiated to agreement. No quality indicators were assessed. We planned descriptive qualitative analysis and appropriate quantitative analysis to examine the prevalence and characteristics of trials enrolling subjects with other than fully informed prospective consent. We find that 44 (8.8%, binomial exact 95% CI 6.5% to 11.6%) of 500 high-impact RCTs did not secure informed consent from at least some subjects. The prevalence of such trials did not change over the 5 years (OR=1.09, z=0.78, p=0.44). A majority (66%) of the trials involved emergency situations, and 40 of 44 (90.9%) of the trials involved emergency interventions, pragmatic designs, were cluster randomized, or a combination of these factors. A qualitative analysis explores the methods of and justifications for waiving informed consent in our sample of RCTs.
    Keywords:  biomedical research; emergency service; hospital; public policy; research; research design
    DOI:  https://doi.org/10.1136/jim-2020-001481
  35. J Med Internet Res. 2020 Oct 02. 22(10): e18835
    Waqas A, Teoh SH, Lapão LV, Messina LA, Correia JC.
      BACKGROUND: In recent decades, advances in information technology have given new momentum to telemedicine research. These advances in telemedicine range from individual to population levels, allowing the exchange of patient information for diagnosis and management of health problems, primary care prevention, and education of physicians via distance learning.OBJECTIVE: This scientometric investigation aims to examine collaborative research networks, dominant research themes and disciplines, and seminal research studies that have contributed most to the field of telemedicine. This information is vital for scientists, institutions, and policy stakeholders to evaluate research areas where more infrastructural or scholarly contributions are required.
    METHODS: For analyses, we used CiteSpace (version 4.0 R5; Drexel University), which is a Java-based software that allows scientometric analysis, especially visualization of collaborative networks and research themes in a specific field.
    RESULTS: We found that scholarly activity has experienced a significant increase in the last decade. Most important works were conducted by institutions located in high-income countries. A discipline-specific shift from radiology to telestroke, teledermatology, telepsychiatry, and primary care was observed. The most important innovations that yielded a collaborative influence were reported in the following medical disciplines, in descending order: public environmental and occupational health, psychiatry, pediatrics, health policy and services, nursing, rehabilitation, radiology, pharmacology, surgery, respiratory medicine, neurosciences, obstetrics, and geriatrics.
    CONCLUSIONS: Despite a continuous rise in scholarly activity in telemedicine, we noticed several gaps in the literature. For instance, all the primary and secondary research central to telemedicine was conducted in the context of high-income countries, including the evidence synthesis approaches that pertained to implementation aspects of telemedicine. Furthermore, the research landscape and implementation of telemedicine infrastructure are expected to see exponential progress during and after the COVID-19 era.
    Keywords:  evidence synthesis; health information technology; research; scientometric analysis; telemedicine; theme
    DOI:  https://doi.org/10.2196/18835
  36. Res Policy. 2021 Jan;50(1): 104127
    Verginer L, Riccaboni M.
      Global cities boast higher rates of innovation as measured through patent and scientific production. However, the source of the location advantage of innovation hubs is still debated in the literature, with arguments ranging from localized knowledge spillovers to network effects. Thanks to an extensive data set of individual scientist career paths, we shed new light on the role of scientist location choices in determining the superior innovative performance of global cities. We analyze the career paths of around two million researchers over a decade across more than two thousand cities around the globe. First, we show that scientists active in global cities are more productive in terms of citation weighted publications. We then show that this superior performance is in part driven by highly prolific scientists moving and remaining preferentially in global cities, i.e., central cities in the international scientist mobility network. The overall picture that emerges is that global cities are better positioned to attract and retain prolific scientists than more peripheral cities.
    Keywords:  Brain circulation; Global cities; Network analysis; Network effects; Scientist mobility
    DOI:  https://doi.org/10.1016/j.respol.2020.104127
  37. BMJ Open. 2020 Sep 28. 10(9): e034667
    Barbosa HP, Roué-Le Gall A, Deloly C, Regnaux JP, Thomas MF.
      INTRODUCTION: Scientists from a wide variety of fields of knowledge are increasingly interested in climate change issues. The importance given to the phenomenon is explained by the uncertainties surrounding it and its consequences not yet fully known. However, there is wide agreement that human activities are modifying the Earth's climate beyond the natural cyclical changes and that these changes impact human health. This scoping review aimed to understand how research on the links between climate change and human health in urban areas is conducted and how this research is approached holistically or not.METHODS AND ANALYSIS: This scoping review is mainly guided by the Arskey and O'Malley scoping review framework. A broad range of databases will be used, including PubMed, ScienceDirect, Web of Science Core Collection, GreenFILE and Information Science & Technology Abstracts. Predefined inclusion and exclusion criteria will be used, with a focus on climate change and human health outcome studies published between January 1990 and July 2019. An interdisciplinary team has formulated search strategies and the reviewers will independently screen eligible studies for final study selection. We will apply a thematic analysis to evaluate and categorise the study findings. We expect to map the research according to the scientific research methods, the scientific fields and the determinants of health studied. Along these lines, we will be able to understand how holistic the research is.
    ETHICS AND DISSEMINATION: No primary data will be collected since all data presented in this review are based on published articles and publicly available documents. Therefore, ethics committee approval is not a requirement. The findings will be disseminated through publication in a peer-reviewed journal, presentations at conferences relevant to the field of this research, as well as presentations to relevant stakeholders.
    Keywords:  public health; qualitative research; statistics & research methods
    DOI:  https://doi.org/10.1136/bmjopen-2019-034667
  38. Pract Radiat Oncol. 2020 Sep 26. pii: S1879-8500(20)30221-6. [Epub ahead of print]
    Novak J, Cui Y, Frankel P, Sedrak MS, Glaser S, Li R, Motwani S, Kavanagh B, Amini A.
      BACKGROUND: and Purpose: Twitter is an increasingly popular social media platform among the health care community. The objective of this analysis is to characterize the profile of radiation oncology-related Tweets and Twitter users over the past 6 years.MATERIAL AND METHODS: Using the web-based social media analytics platform, Symplur Signals, we filtered Tweets containing at least one of the following hashtags or key words: #radonc, #radiationoncology, "rad onc," or "radiation oncology." We evaluated radiation oncology-related Twitter activity occurring from October 2014 through March 2020 for Tweet frequency, Tweet content, and the individuals or groups posting Tweets. We identified the most influential Twitter users contributing radiation oncology-related Tweets.
    RESULTS: From 2014 to 2020, the quarterly volume of radiation oncology-related Tweets increased from 5,027 to 29,763. Physicians contributed the largest growth in Tweet volume. Academic radiation oncologists comprise 60% of the most influential Twitter accounts responsible for radiation oncology-related content. The number of radiation oncology resident physicians on Twitter increased from 25 to 328 over the past 6 years. 20% of radiation oncology residency programs have a Twitter account. 71% of radiation oncology-related Tweets generated direct communication via mentions. 59% of Tweets contain links to external sources including scientific articles.
    CONCLUSIONS: The number of physicians contributing radiation oncology-related Twitter content has increased significantly in recent years. Academic radiation oncologists are the primary influencers of radiation oncology-related Twitter activity. Twitter is used by radiation oncologists both to professionally network and to discuss findings related to the field. There remains the opportunity for radiation oncologists to broaden their audience on Twitter to encompass a more diverse community including patients.
    Keywords:  #radiationoncology; #radonc; radiation oncology; social media; twitter
    DOI:  https://doi.org/10.1016/j.prro.2020.09.008
  39. J Indian Soc Pedod Prev Dent. 2020 Jul-Sep;38(3):38(3): 209-210
    Baliga S.
      
    DOI:  https://doi.org/10.4103/0970-4388.296642
  40. Poult Sci. 2020 Oct;pii: S0032-5791(20)30441-7. [Epub ahead of print]99(10): 4758-4768
    Maghsoudi A, Vaziri E, Feizabadi M, Mehri M.
      Sheep red blood cells (SRBC) are commonly employed by scientists to address humoral immune responses in poultry. While SRBC are closely related to the study of humoral immunity in poultry, the initial purpose of much research did not focus on the mechanisms involved. Here, we provide a qualitative approach and utilize scientometric techniques, including trend analyses, scientific collaborations and mapping, and word co-occurrence evaluations, to summarize the role of SRBC in the poultry studies. First, a search strategy on Web of Science (WoS) was conducted to find publications that included SRBC in the poultry studies. Publications were partitioned into 4 categories: nutrition, genetics, microbiology, and physiology. For scientometric evaluation, scientific maps and networks were produced to clarify the occurrence of SRBC in the poultry studies. Data used included 702 publications over a period of 50 y (1968-2018) that were retrieved from the WoS database. About 95% of the publications were published in English language. Indigenous, experimental, and commercial chickens, quail, and medicinal plants field/topics were the main subjects of publications. In recent years, authors have used SRBC to study humoral immune response as a secondary aim of their research, especially when poultry production/performance was studied. This was especially the case in recent decades for studies in poultry nutrition. Analysis of keywords co-occurrence showed that the phrase SRBC mostly occurred with chickens, immune response, and especially with broilers. Moreover, the "medicinal plants" are becoming important especially for research on broilers and the reduced use of antibiotics in feed. Consequently, in addition to studying the medicinal plants, finding antibiotic replacements, and/or growth performance in the birds, humoral immunity is suggested to be investigated using SRBC. Moreover, interdisciplinary studies with the cooperation of scientists from agriculture, veterinary, immunology, biochemistry and molecular biology, and toxicology will develop in the future.
    Keywords:  SRBC; broilers; chicken; humoral immunity; immune responses; medicinal plants
    DOI:  https://doi.org/10.1016/j.psj.2020.06.058
  41. Chin J Integr Med. 2020 Sep 30.
    Shen H, Zhu WK, Lu Z, Zhou HC.
      OBJECTIVE: To summarize current hotspots and predict the potential trends in traditional drugs of diabetes treatment for further research.METHODS: Publications on the application of traditional drugs in diabetes treatment were searched from PubMed without language limits. Highly frequent MeSH terms were identified through Bibliographic Item Co-Occurrence Matrix Builder (BICOMB). Biclustering analysis results were visualized utilizing the gCLUTO software. Finally, a strategic diagram was generated.
    RESULTS: Totally 2,386 relevant publications were obtained from PubMed on November 9th, 2018, and 69 highly frequent MeSH terms were identified. Biclustering analysis revealed that these highly frequent MeSH terms were classified into 7 clusters. After calculating the density and centrality of each cluster, strategy diagram was presented. Cluster 0 "Chinese medicine monomers such as antioxidant and hypoglycemic effects" was considered as the most potential research hotspot.
    CONCLUSIONS: In this study, we found 7 topics related to the application of traditional drugs in diabetes treatment. The molecular mechanisms of Chinese medicine monomers in diabetes could become a potential hotspot with high centricity and low density.
    Keywords:  Chinese medicine; MeSH term; bibliometrics; diabetes; hotspot; traditional drug
    DOI:  https://doi.org/10.1007/s11655-020-3322-1
  42. Environ Sci Pollut Res Int. 2020 Oct 01.
    Zhao G, Geng Y, Sun H, Tian X, Chen W, Wu D.
      Green consumption can facilitate sustainable industrial development and improve the overall efficiency of resource utilization. In response to rapid economic development and increasing environmental emissions, it is critical to promote green consumption so that the whole society can move toward sustainable development. This study aims to systematically review studies on green consumption by means of meta-analysis, bibliometric analysis, and social network analysis. The results show that green consumption is an interdisciplinary research field, involving environmental science, social science, medical science, economics, and other disciplines. Most productive countries, institutions, authors are identified so that the new researchers in this field can find their research partners. Keywords analysis results help identify the research hotpots in this field. It is suggested that future green consumption research should focus on behavior mechanism, stakeholder coordination, and policy evaluation. In general, the results obtained from this study provide valuable information for researchers and practitioners to promote green consumption research.
    Keywords:  Environmental economics; Green consumption; Knowledge mapping; Meta-analysis; Sustainable development
    DOI:  https://doi.org/10.1007/s11356-020-11029-y