bims-evares Biomed News
on Evaluation of research
Issue of 2020‒04‒26
28 papers selected by
Thomas Krichel
Open Library Society

  1. Medicine (Baltimore). 2020 Apr;99(17): e19659
    Chen Q, Li Y, Wang X, Li H.
      BACKGROUND: The number of citations a scientific paper has received indicates its impact within any medical field. We performed a bibliometric analysis to highlight the key topics of the most frequently cited 100 articles on perianal fistula to determine the advances in this field.METHODS: The Scopus database was searched from 1960 to 2018 using the search terms "perianal fistula" or "anal fistula" or "fistula in ano" or "anal fistulae" or "anorectal fistulae" including full articles. The topic, year of publication, publishing journal, country of origin, institution, and department of the first author were analyzed.
    RESULTS: The median number of citations for the top 100 of 3431 eligible papers, ranked in order of the number of citations, was 100 (range: 65-811), and the number of citations per year was 7.5 (range: 3.8-40.1). The most-cited paper (by Parks et al in 1976; 811citations) focused on the classification of perianal fistula. The institution with the highest number of publications was St Mark's Hospital, London, UK. The most-studied topic was surgical management (n = 47). The country and the decade with the greatest number of publications in this field were the USA (n = 34) and the 2000s (n = 50), respectively.
    CONCLUSION: The 100 most frequently cited manuscripts showed that surgical management had the greatest impact on the study of perianal fistula. This citation analysis provides a reference of what could be considered the most classic papers on perianal fistula, and may serve as a reference for researchers and clinicians as to what constitutes a citable paper in this field.
  2. Global Spine J. 2020 May;10(3): 353-360
    Aldawsari K, Alotaibi MT, Alsaleh K.
      Study Design: Bibliographic analysis.Objective: The aim of this study is to identify the most cited studies on lumbar spondylolisthesis and report their impact in spine field.
    Methods: Thomson Reuters Web of Science-Science Citation Index Expanded was searched using title-specific search "spondylolisthesis." All studies published in English language between 1900 and 2019 were included with no restrictions. The top 100 cited articles were identified using "Times cited" arranging articles from high to low according to citation count. Further analysis was made to obtain the following items: article title, author's name and specialty, country of origin, institution, journal of publication, year of publication, citations number, study design.
    Results: The citation count of the top 100 articles ranged from 68 to 589. All published between 1932 and 2016. Among 20 journals, Spine had the highest number of articles (49), with citation number of 6155 out of 13 618. Second ranked was Journal of Bone and Joint Surgery with 15 articles and total citations of 3023. With regard to the primary author's specialty, orthopedic surgeons contributed to the majority of top 100 list with 82 articles, and neurosurgery was the second specialty with 11 articles. The United States had produced more than half of the list with 59 articles. England was the second country with 7 articles. Surgical management of degenerative lumbar spondylolisthesis was the most common discussed topic.
    Conclusion: This article identifies the top 100 influential articles on lumbar spondylolisthesis and recognizes an important aspect of knowledge evolution served by leading researchers as they guided today's clinical decision making in spondylolisthesis.
    Keywords:  bibliographic review; citation analysis; lumbar spine; lumbar spondylolisthesis
  3. Gastroenterol Hepatol Bed Bench. 2020 ;13(2): 101-114
    Ahmad SJ, Ahmed AR, Kowalewski KF, Nickel F, Rostami K, Stocker CJ, Hakky SM, Archid R, McWhinnie D, Mohajer-Bastami A, Seimenis DS, Ahmad S, Mansour S, Ahmed MH, Mital D, Exadaktylos AK.
      Aim: This review provides a comprehensive overview of more than 100 of the most cited studies in general medical journals and evaluates whether citations predict the quality of a scientific article.Background: The number of citations is commonly used as a measure of the quality and impact of a scientific article. However, it is often criticised that the number of citations is in fact a poor indicator of the true quality, as it can be influenced by different factors such as current trends.
    Methods: This review was conducted in line with the PRISMA guidelines. The Journal Citation Report (JCR) within Incites allowed the evaluation and comparison of articles, published in general medical journals, using far-reaching citation data drawn from scholarly and technical journals and conference proceedings. All steps of the review were performed in duplicate and conflicts were resolved through consensus.
    Results: The 100 most cited articles published from 1963 until the end of 2018 were identified. The number of citations ranged from 4012 to 31853. Most of the articles were published in the 2000's, followed by the 1990's, 1980's, 1970's and 1960's, respectively. All of the articles were published in five journals. There were 50 studies at level II, 28 at level V, 10 at level IV, 7 at level III, and 5 at Level I.
    Conclusion: This systematic review provides an overview of the most cited articles, published in general medical journals. The number of citations provides an indication of the quality of evidence. However, researchers and clinicians should use standardized assessment tools rather than solely rely on the number of citations in order to judge the quality of published articles.
    Keywords:  Article quality; Bibliometrics; Citation classics; General medical journals; Level of evidence; Most-cited articles
  4. Indian J Ophthalmol. 2020 May;68(5): 738-744
    Ramadoss G, Yadalla D.
      Purpose: To perform an analysis of ophthalmic literature published by the Indian journal of ophthalmology (IJO) between 2005 and 2017 using scientometric techniques.Methods: The bibliographic records of all the literature published in the study period were collected from PubMed and exported as XML into Microsoft access for scientometric analysis. Subspecialty wise distribution across time, type of articles published (original articles, case reports, review articles, editorials, and letter to editor), reference analysis, author productivity analysis and citation analysis were performed as per well-established scientometric methodology.
    Results: A total of 2,633 papers were published in the IJO during the study period. Articles related to vitreoretinal diseases contributed 23% of all the articles published (n = 598) followed by corneal diseases (n = 313, 12%), and cataract (n = 293, 11%). There were equal numbers of case reports (n = 894, 34%) and original articles (n = 862, 33%) though case reports reduced over time. A total of 5490 unique authors from 64 countries published in the IJO with majority authors (63%) from India. Less than 80% of articles published in the IJO were cited (n = 2051, 78%) by 24,592 articles with retina-related papers contributing 20% of all citations. Original articles had three times more likelihood of being cited compared to case reports.
    Conclusion: The: IJO showed a steady increase in the number of publications from year to year. Papers from the vitreoretinal domain were the commonest and were cited most often. Original articles and case reports contributed equally to the published content though the former were cited much more frequently than the latter.
    Keywords:  IJO; Indian Journal of Ophthalmology; Indian Ophthalmic Research; ophthalmology; scientometric
  5. Int J Environ Res Public Health. 2020 Apr 16. pii: E2753. [Epub ahead of print]17(8):
    Moreno-Guerrero AJ, Gómez-García G, López-Belmonte J, Rodríguez-Jiménez C.
      Information and communication technologies (ICT) is a major element of today's society with great potential that can offer both advantages and disadvantages. Addiction to the Internet and social networks is a growing problem in all age groups. Education is the context in which to work and train in the correct use of these media. The objective of the study focuses on knowing the scientific production and the performance of the concepts "addiction" and "internet" (ADIN). A bibliometric methodology complemented with the scientific mapping technique was followed. Different processes related to the quantification, analysis, evaluation, and estimation of scientific documents were carried out. The literature was analyzed by specific programs such as SciMAT, Analyze Results, and Creation Citation Report. The unit of analysis was specified in 5644 scientific publications extracted from Web of Science (WoS), belonging to the period of years between 1996 and 2019. The results showed that the evolution in the study of the addiction to the Internet is constant and continuous, with articles in English being the most used means to present the information on the part of the investigators. In addition, the subject of study was based on time, given that the coincidence of key words between the periods analyzed was high. In conclusion, the importance of promoting healthy living habits that include responsible use of the Internet are discussed.
    Keywords:  Web of Science; addiction; bibliometric analysis; internet; scientific mapping; scientific production
  6. PLoS One. 2020 ;15(4): e0231735
    Jappe A.
      Despite growing demand for practicable methods of research evaluation, the use of bibliometric indicators remains controversial. This paper examines performance assessment practice in Europe-first, identifying the most commonly used bibliometric methods and, second, identifying the actors who have defined wide-spread practices. The framework of this investigation is Abbott's theory of professions, and I argue that indicator-based research assessment constitutes a potential jurisdiction for both individual experts and expert organizations. This investigation was conducted using a search methodology that yielded 138 evaluation studies from 21 EU countries, covering the period 2005 to 2019. Structured content analysis revealed the following findings: (1) Bibliometric research assessment is most frequently performed in the Nordic countries, the Netherlands, Italy, and the United Kingdom. (2) The Web of Science (WoS) is the dominant database used for public research assessment in Europe. (3) Expert organizations invest in the improvement of WoS citation data, and set technical standards with regards to data quality. (4) Citation impact is most frequently assessed with reference to international scientific fields. (5) The WoS classification of science fields retained its function as a de facto reference standard for research performance assessment. A detailed comparison of assessment practices between five dedicated organizations and other individual bibliometric experts suggests that corporate ownership and limited access to the most widely used citation databases have had a restraining effect on the development and diffusion of professional bibliometric methods during this period.
  7. Health Place. 2020 Jan;pii: S1353-8292(19)30952-9. [Epub ahead of print]61 102202
    Moon G, Pearce J.
      To mark 25 years of Health & Place Health & Place, we identify and appraise some key contributions to the journal over this period. We use citation data to identify 'classics' from the journal's back catalogue. We also examine trends in the international reach and disciplinary homes of our authors. We show that there has been a near 7-fold increase in the number of published papers between the early and most recent years of the journal and that the journal's citation levels are amongst the top 2% of social science journals. Amongst the most cited papers, some clear themes are evident such as physical activity, diet/food, obesity and topics relating to greenspace. The profile of the journal's authors is becoming more internationally diverse, represents a broader range of disciplines, and increasingly demonstrating cross/interdisciplinary ways of working. Although Anglophone countries have led the way, there is an increasing number of contributions from elsewhere including emerging economies such as China. We conclude with some comments on likely future directions for the journal including enduring concerns such as greenspace, obesity, diet and unhealthy commodities (alcohol, tobacco, ultra-processed food) as well as more recent directions including planetary health, longitudinal and lifecourse analyses, and the opportunities (and challenges) of big data and machine learning. Whatever the thematic concerns of the papers over next 25 years, we will continue to welcome outstanding research that is concerned with the importance place makes to health.
  8. Eur Heart J. 2020 Apr 19. pii: ehaa211. [Epub ahead of print]
    Ladeiras-Lopes R, Clarke S, Vidal-Perez R, Alexander M, Lüscher TF, .
      AIMS: The association between the dissemination of scientific articles on Twitter and online visibility (including Altmetric score) is still controversial and the impact on citation rates has never been addressed for cardiovascular medicine journals.METHODS AND RESULTS: The ESC Journals Study randomized 696 papers published in the ESC Journals family (March 2018-May 2019) for promotion on Twitter or to a control arm (with no active tweeting from ESC channels) and aimed to assess if Twitter promotion was associated with an increase in citation rate (primary endpoint) and Altmetric score. This is a preliminary analysis of 536 articles (77% of total) published until December 2018 (therefore, papers published at least 6 months before collecting citation and Altmetrics data). In the analysis of the primary endpoint, Twitter promotion of articles was associated with a 1.43 (95% confidence interval 1.29-1.58) higher rate of citations, and this effect was independent of the type of article. Both Altmetric score and number of users tweeting were positively associated with the number of citations in both arms, with evidence of a stronger association (interaction) in the Twitter arm.
    CONCLUSION: Therefore, a social media strategy of Twitter promotion for cardiovascular medicine papers seems to be associated with increased online visibility and higher number of citations. The final analysis will include 696 papers and 2-year scientific citation rate and is estimated to be concluded in March 2021.
    Keywords:  Altmetrics; Cardiovascular articles; Citations; Randomized study; Social media; Twitter
  9. F1000Res. 2019 ;8 1718
    AlRyalat SA, Abukahel A, Elubous KA.
      Background: Randomized controlled trials (RCTs) are situated at the top of hierarchy of evidence-based medicine, where its number and quality are important in the assessment of quality of evidence in a medical field. In this study, we aim to assess the status of RCTs in Ophthalmology. Methods: On 15 th of May 2019, we performed a PubMed search for randomized controlled trials published in the field of ophthalmology using relevant filters and search terms. We categorized the results into specific topics in ophthalmology according to Medical Subject Heading (MeSH) database classification system. We used Altmetric explorer to identify journals and articles with the highest number of RCTs and highest citations. Results: We found a total of 540,427 publications in the field of ophthalmology, of which only 11,634 (2.15%) of them were RCTs. 'Retinal diseases' was the topic with the highest number of RCTs, followed by 'glaucoma' and 'conjunctival diseases'. The trial with highest number of citations was on retinal diseases. Only around 18% of all ophthalmology RCTs are published in the top 10 ophthalmology journals, with a maximum percentage of RCTs was (5.53%) published in Ophthalmology. Conclusion: RCTs in ophthalmology primarily concern the retina, glaucoma, and a few other sub-topics, with little focus on sclera, orbit, and the eyelids. Most of the high impact RCTs are published in non-ophthalmology journals.
    Keywords:  Ophthalmology; Randomized Controlled Trials; PubMed; Retina; Journals; Bibliometrics.
  10. Cureus. 2020 Mar 21. 12(3): e7357
    Chahrour M, Assi S, Bejjani M, Nasrallah AA, Salhab H, Fares M, Khachfe HH.
      BACKGROUND: The novel coronavirus disease 2019 (COVID-19) has impacted many countries across all inhabited continents, and is now considered a global pandemic, due to its high rate of infectivity. Research related to this disease is pivotal for assessing pathogenic characteristics and formulating therapeutic strategies. The aim of this paper is to explore the activity and trends of COVID-19 research since its outbreak in December 2019.METHODS: We explored the PubMed database and the World Health Organization (WHO) database for publications pertaining to COVID-19 since December 2019 up until March 18, 2020. Only relevant observational and interventional studies were included in our study. Data on COVID-19 incidence were extracted from the WHO situation reports. Research output was assessed with respect to gross domestic product (GDP) and population of each country.
    RESULTS: Only 564 publications met our inclusion criteria. These articles came from 39 different countries, constituting 24% of all affected countries. China produced the greatest number of publications with 377 publications (67%). With respect to continental research activity, Asian countries had the highest research activity with 434 original publications (77%). In terms of publications per million persons (PPMPs), Singapore had the highest number of publications with 1.069 PPMPs. In terms of publications per billion-dollar GDP, Mauritius ranked first with 0.075.
    CONCLUSION: COVID-19 is a major disease that has impacted international public health on a global level. Observational studies and therapeutic trials pertaining to COVID-19 are essential for assessing pathogenic characteristics and developing novel treatment options.
    Keywords:  bibliometric; coronavirus disease; covid19; novel coronavirus; public health
  11. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2020 Apr 25. 37(2): 236-245
    Zhang L, Li B, Jia P, Pu J, Bai B, Li Y, Zhu P, Li L, Zeng G, Zhao X, Dong S, Liu M, Zhang N.
      The SARS-CoV-2 has been spread to 26 countries around the world since its outbreak. By February 16, 2020, more than 68 000 people had been diagnosed with COVID-19. Researchers from all over the world have carried out timely studies on this public health emergency and produced a number of scientific publications. This review aims to re-analyze and summarize the current research findings in a timely manner to guide scholars in relevant fields to further SARS-CoV-2 research and assist healthcare professionals in their work and decision-making. The SARS-CoV-2 related terms were selected in both English and Chinese and were searched in several major databases, including Pubmed, Web of Science, CNKI, Wanfang, and VIP databases. The reference list of each search result was screened for relevance, which was further supplemented to the search results. The included studies were categorized by topics with key characteristics extracted, re-analyzed, and summarized. A total of 301 articles were finally included with 136 in Chinese and 165 in English. The number of publications has rapidly increased since mid-January, 2020, and a peak day was 6th February on which 50 articles were published. The top three countries publishing articles were China, the United States and the United Kingdom. The Lancet and its specialty journals have published the most articles, with contribution also from journals such as New England Journal of Medicine ( NEJM), The Journal of the American Medical Association ( JAMA), and Nature. All articles were categorized into epidemiology, clinical diagnosis and treatment, basic research, pregnant women and children, mental health, epidemic prevention & control, and others. The literatures related to SARS-CoV-2 are emerging rapidly. It is necessary to sort out and summarize the research topic in time, which has a good reference value for staff in different positions. At the same time, it is necessary to strengthen the judgment of the quality of literatures.
    Keywords:  COVID-19; SARS-CoV-2; bibliometrics; recommended learning list
  12. J Spine Surg. 2020 Mar;6(1): 26-32
    Goss M, McNutt S, Bible J.
      Background: The goal of this study was to analyze the trends in authorship and study characteristics in Spine using two overlapping ten-year time periods: 2004-2014 and 2007-2017. To our knowledge, no other literature reports study characteristics and authorship in the same time period for spine that would allow for the assessment of confounding factors of trends.Methods: Authorship and study characteristic data was collected from all scientific manuscripts published in Spine during the years of 2004, 2007, 2014, and 2017. Basic statistics and Kruskal-Wallis test were used to analyze the data.
    Results: We found a significant increase in total number of authors (P<0.0001) without discrepancy of unequivocal increases in author degree type: MD/Equivalent (P≤0.0001), PhD/Doctorate (P=0.0017), Masters (P=0.0015), and Bachelors (P≤0.0001). We observed an increase in industry authorship (P≤0.0001), but without a significant increase in industry funding during the same time span. Increases in administration database studies (P≤0.0001) and economic/value studies (P≤0.0001) were also noted. A significant change in percentage of articles with trauma pathology (decrease, P<0.0001) and deformity (increase, P=0.0002) occurred. The number of multi-institutional studies increased (P≤0.0001), while no change in the number of multi-disciplinary studies.
    Conclusions: Increases in author number for spine articles over time are a result of a general increase in authors in all degree types, not just non-doctorate degrees. This may be potentially influenced by the increase in multi-institutional studies. From 2004-2017, higher percentages of articles focus on economics. An increase in industry authorship without a corresponding increase in funding suggests industry's more 'hands-on' approach to publication results from their funded studies.
    Keywords:  Authorship; economics; interprofessionalism; study design
  13. Br Dent J. 2020 Apr;228(8): 631-636
    Lee YWJ, Wong CH, Cheong C, Burnside G.
      Introduction Abstract presentations at scientific meetings provide a platform to share and discuss new research. It would be desirable if the abstracts were subsequently published in peer-reviewed journals as this is the most accepted method to allow the dissemination of scientific research.Aims To determine the publication rate of abstracts presented at the International Association for Dental Research (IADR) general sessions in 2014 and 2015, and factors involved from presentation to publication.Design A systematic search of PubMed and Google Scholar databases was performed of the abstracts identified. Abstract titles, author's last name and key words were used to identify whether an abstract resulted in a publication. Abstracts published in full-length articles were then analysed.Results There were a total number of 5,847 abstracts presented at 2014 and 2015 IADR general sessions. 60.9% of posters presented and 72.1% of oral presentations were consecutively published as a full-length article. The average publication rate of abstracts was 63.3%. USA had the highest number of published abstracts with a publication rate of 64.9%, followed by Brazil and Japan which had 62.3% and 67.9%, respectively. The mean time from presentation to publication was 13 months.Conclusion There is scope for further guidance to ensure scientific work is properly disseminated and published.
  14. J Physician Assist Educ. 2020 Apr 23.
    Hegmann TE.
      PURPOSE: Academic scholarship continues to challenge physician assistant (PA) educators in the United States, who typically enter academia with little experience in research or publication. Consequently, difficulty with navigating the promotion process might be expected to impact both job satisfaction and retention of PA faculty. Providing reasonable benchmarks for scholarship is one focus of this project, along with exploration of relationships among publication success, gender, job stressors, program support, and intent to leave academia.METHODS: Deidentified data from the online 2017 Faculty & Directors Survey was obtained from the Physician Assistant Education Association (PAEA), including gender, academic rank, program role, degree, publication numbers, and variables measuring program support, stressors, and intent to leave the institution or academia. Individual response rate was 60.3%, N = 1009. SPSS-v25 was used for data analysis.
    RESULTS: Respondents were 65% female. The mean number of total publications was 2.7 (down from 4.2 in 2010); the median was zero with 50.6% reporting no publications during their career. Almost half (45.5%) of PA faculty were stressed by research or publishing demands; 53.6% were stressed by the promotion process. Physician assistant educators stressed by promotion were more likely to consider leaving their institution or academia as a whole (Fisher's exact, P < .001 for both).
    CONCLUSION: This study updates publication benchmarks for PA educators. Scholarship levels have dropped since 2010, likely related to the recent influx of junior faculty. Navigating the promotions process is a significant occupational stressor for PA educators and is associated with faculty intent to leave academia.
  15. AMIA Annu Symp Proc. 2019 ;2019 655-663
    McCoy AB, Sittig DF, Lin J, Wright A.
      To overcome limitations of previously developed scientific productivity ranking services, we created the Biomedical Informatics Researchers ranking website ( The website is composed of four key components that work together to create the automatically updating ranking website: 1) list of biomedical informatics researchers, 2) Google Scholar scraper, 3) display page, and 4) updater. The interactive website has facilitated identification of leaders in each of the key citation statistics categories (i.e., number of citations, h-index, and i10-index), and it has allowed other groups, such as tenure and promotions committees, to more effectively and efficiently evaluate researchers and interpret the various citation statistics reported by candidates. Creation of the biomedical informatics researcher ranking website highlights the vast differences in scholarly productivity among members of the biomedical informatics research community. Future efforts are underway to add new functionality to the website and to expand the work to identify top papers in biomedical informatics.
  16. Orthopedics. 2020 Apr 20. 1-7
    Williams BR, Freking WG, Ridley TJ, Agel J, Swiontkowski MF.
      As attendees of orthopedic meetings consider how to integrate presented information into their practice, it is helpful to consider the quality of the data presented. One surrogate metric is the proportion of and changes to presented abstracts that become journal publications. With this study, using the 2010 American Academy of Orthopaedic Surgeons (AAOS) Annual Meeting abstracts, the authors sought to answer the following questions: Did the publications following abstract presentations differ in terms of the conclusions, study subjects, or coauthors? What proportion of abstracts was published? What are the most common subtopics and journals, and what is the most common author country? Keywords and authors from the 2010 AAOS Annual Meeting proceedings program (698 podium and 548 poster abstracts) were searched in PubMed, Embase, and Google Scholar. If a publication resulted, differences in the conclusion, number of study subjects, and authorship between the abstract and the journal publication were tabulated. The proportion of abstracts published, specialty subtopics, authorship country, and journals of publication were collected. At journal publication, 1.7% of podium and 1.7% of poster conclusions changed. Mean number of authors for podium and poster increased significantly (P<.001), and 30% of podium and 44% of poster had a change in the number of study subjects. The overall journal publication percentage was 61% (68% podium and 53% poster). The majority of the authors were from the United States. The most common journal was The Journal of Bone & Joint Surgery. It is important to evaluate the usefulness and clinical applicability of meetings, especially the final disposition of conference abstracts, from various angles to ensure that they are as worthwhile and educational as possible. [Orthopedics. 2020;xx(x):xx-xx.].
  17. J R Soc Interface. 2020 Apr;17(165): 20200135
    Li J, Yin Y, Fortunato S, Wang D.
      Throughout history, a relatively small number of individuals have made a profound and lasting impact on science and society. Despite long-standing, multi-disciplinary interests in understanding careers of elite scientists, there have been limited attempts for a quantitative, career-level analysis. Here, we leverage a comprehensive dataset we assembled, allowing us to trace the entire career histories of nearly all Nobel laureates in physics, chemistry, and physiology or medicine over the past century. We find that, although Nobel laureates were energetic producers from the outset, producing works that garner unusually high impact, their careers before winning the prize follow relatively similar patterns to those of ordinary scientists, being characterized by hot streaks and increasing reliance on collaborations. We also uncovered notable variations along their careers, often associated with the Nobel Prize, including shifting coauthorship structure in the prize-winning work, and a significant but temporary dip in the impact of work they produce after winning the Nobel Prize. Together, these results document quantitative patterns governing the careers of scientific elites, offering an empirical basis for a deeper understanding of the hallmarks of exceptional careers in science.
    Keywords:  Nobel Prize; big data; science of science; scientific careers
  18. Environ Sci Pollut Res Int. 2020 Apr 19.
    Shasha ZT, Geng Y, Sun HP, Musakwa W, Sun L.
      With increasing attentions on climate change, solid wastes, over-tourism, and improved environmental awareness worldwide, eco-tourism has been widely promoted worldwide. This requires that governmental agencies at different levels should prepare appropriate policies to facilitate eco-tourism and local communities should take necessary actions to preserve their natural resources, protect their environment, and support sustainable tourism. Academically, literatures on eco-tourism have increased faster with an annual growth rate of 10-30% during the recent years. Under such a circumstance, it is important to conduct a comprehensive review so that research progress on eco-tourism can be summarized and future research directions can be identified. Based on 1771 publications published during 2001-2018, a systematic method combining bibliometric analysis and network analysis is applied in this study to uncover the dynamic trends, academic collaboration, and research hotspots related with eco-tourism. Results show that the total number of relevant publications has gradually increased. Key journals include Journal of Hospitality and Tourism Management, Annals of Tourism Research, Conservation Biology, and Biological Conservation. Authors from USA have the most publications and international co-authorships, while the most influential institution is the Chinese Academy of Science. Moreover, research keywords have been identified, including eco-tourism, management, biodiversity, national park, sustainability, and sustainable tourism. Research findings of this study provide valuable insights to further improve eco-tourism research so that this emerging research field can be proactively fostered.
    Keywords:  Bibliometric review; Eco-tourism; Governance; Green travel; Low-carbon tourism; Network analysis
  19. J Med Internet Res. 2020 Feb 08.
    Mavragani A.
      BACKGROUND: Web-based sources are increasingly employed in the analysis, detection, and forecasting of diseases and epidemics, and in predicting human behavior towards several health topics. This use of the Internet has come to be known as infodemiology; a concept introduced by Gunther Eysenbach. Infodemiology and infoveillance studies use web-based data and have become an integral part of health informatics research over the past decade.OBJECTIVE: The aim of this paper is to provide a scoping review of the state-of-the-art in infodemiology, along with the background and history of the concept, identify sources and health categories and topics, elaborate on the validity of the employed methods, and discuss the gaps identified in current research.
    METHODS: The PRISMA guidelines are followed in order to extract the publications that fall under the umbrella of infodemiology and infoveillance from the JMIR, PubMed, and Scopus databases. A total of 338 documents are extracted for assessment.
    RESULTS: The vast majority of the studies, i.e. 83.43% (282/339), are published with JMIR Publications. The "Journal of Medical Internet Research" features almost half of the publications, i.e. 168/338 (49.70%), and "JMIR Public Health and Surveillance" more than one fifth of the examined studies, i.e. 74/338 (21.89%). The interest in the subject is increasing every year, with 2018 featuring more than one fourth of the total publications (26.33%; 89/338), while counting both 2017 and 2018, the publications account for more than half (50.59%; 171/338) of the total number of publications in the last decade. The most popular source is Twitter with 44.97% (152/338), followed by Google with 24.56% (83/338), Websites/Platforms with 13.91% (47/338), Blogs/Forums with 10.06% (34/338), Facebook with 8.88% (30/338), and other search engines with 5.62% (19/338). As for the subject examined, conditions/diseases with 17.16% (58/338) and epidemics/outbreaks with 15.68% (53/338) are the most popular categories identified in this review, followed by health care (11.54%; 39/338), drugs (10.36%; 40/338), and smoking/alcohol (8.58%; 29/338).
    CONCLUSIONS: The field of infodemiology is becoming increasingly popular, employing innovating methods and approaches for health assessment. The use of Web-based sources that provide us with information that would not be accessible otherwise and also tackle the issues arising from the time-consuming traditional methods, shows that infodemiology plays a very important role in health informatics research.
  20. PLoS One. 2020 ;15(4): e0230416
    Colavizza G, Hrynaszkiewicz I, Staden I, Whitaker K, McGillivray B.
      Efforts to make research results open and reproducible are increasingly reflected by journal policies encouraging or mandating authors to provide data availability statements. As a consequence of this, there has been a strong uptake of data availability statements in recent literature. Nevertheless, it is still unclear what proportion of these statements actually contain well-formed links to data, for example via a URL or permanent identifier, and if there is an added value in providing such links. We consider 531, 889 journal articles published by PLOS and BMC, develop an automatic system for labelling their data availability statements according to four categories based on their content and the type of data availability they display, and finally analyze the citation advantage of different statement categories via regression. We find that, following mandated publisher policies, data availability statements become very common. In 2018 93.7% of 21,793 PLOS articles and 88.2% of 31,956 BMC articles had data availability statements. Data availability statements containing a link to data in a repository-rather than being available on request or included as supporting information files-are a fraction of the total. In 2017 and 2018, 20.8% of PLOS publications and 12.2% of BMC publications provided DAS containing a link to data in a repository. We also find an association between articles that include statements that link to data in a repository and up to 25.36% (± 1.07%) higher citation impact on average, using a citation prediction model. We discuss the potential implications of these results for authors (researchers) and journal publishers who make the effort of sharing their data in repositories. All our data and code are made available in order to reproduce and extend our results.
  21. Endocr Metab Immune Disord Drug Targets. 2020 Apr 20.
    Wang YQ, Chen YB, Xu D, Cui YL.
      OBJECTIVE: Energy metabolism disorder is one of the causes of Parkinson's disease (PD). Rodents such as rats and mice are often used to establish animal models of PD. This paper used a bibliometric method to analyze the studies of rat and mouse PD models published between 2009 and 2018 in the Web of Science (WOS) database using CiteSpace V software. In addition, we conducted a literature review on the development status and research hotspots in this field in the past 10 years.METHODS: The related articles on rat and mouse PD models were retrieved from the WOS database, and an analysis of the keywords in these articles was conducted using CiteSpace V. A timeline graph was developed by the software in order to show the focus of researchers in the PD field.
    RESULTS: A total of 8,636 articles were obtained. Results of the cluster analysis in the PD field such as neuroinflammation, oxidative stress and autophagy contributed to the systematic review about the pathogenesis of PD. At the same time, based on the property of the model drug, this review has summarized and compared different administration techniques and mechanisms of 6- hydroxydopamine (6-OHDA), 1-methyl-4-phenyl-1, 2, 4, 5-tetrahydropyridine (MPTP), paraquat and rotenone.
    CONCLUSION: According to the bibliometric analysis, studies on PD were focused on the mechanisms of oxidative stress, neuroinflammation and autophagy. Activated microglia releases inflammatory cytokines; mitochondrial dysfunction is caused by oxidative damage of mitochondrial protein; abnormal autophagy-lysosome pathway can lead to abnormal protein deposition in dopaminergic neurons. In addition, although many animal models of PD have been established, there are some limitations of such models. Therefore, it is necessary to develop models that accurately mimic human PD.
    Keywords:  6-OHDA; Animal models; Bibliometrics; MPTP; Paraquat; Parkinson's disease; Pathogenesis; Rotenone.
  22. J Clin Gastroenterol. 2020 Apr 21.
    Schöffel N, Brüggmann D, Klingelhöfer D, Bendels MHK, Groneberg DA.
      BACKGROUND AND AIMS: Despite decades of effort, numerous aspects on ulcerative colitis (UC) remain unknown and require further investigation. Scientists experience numerous challenges to survey >40,000 items that have been published on UC since 1900, to evaluate their scientific impact or to identify collaborative networks publishing the most relevant work. Hence, no current, detailed and comprehensive knowledge regarding the worldwide research architecture of UC has been established until now.METHODS: We conducted a scientometric study employing the previously validated NewQIS (New Quality and Quantity Indices in Science) platform to quantify the global research activity in the field of UC. Hereby, the total research productivity, scientific output of countries, individual institutions, authors, journals, their collaborative networks as well as semiqualitative aspects were assessed. Results were visualized via state-of-the-art density-equalizing mapping projections.
    RESULTS: The United States, Germany, and the United Kingdom play leading roles regarding scientific activity, multilateral and bilateral cooperations. Within the past decades, research on UC diversified into a field covering numerous subject areas. Recently published studies predict that the scientific progress will be mainly depending on international cooperations; we can confirm that development by now.
    CONCLUSIONS: Scientometrics proofed to be a useful methodical approach to evaluate quantitative and semiqualitative aspects regarding UC. Also, we conclude that the influence of international cooperations on the scientific progress in the field of UC is constantly progressing.
  23. Front Public Health. 2020 ;8 91
    Liu C, Liu Z, Zhang Z, Li Y, Fang R, Li F, Zhang J.
      The etiology and pathogenesis of Parkinson's disease (PD) have not yet been clearly described. Both genetic and environmental factors contribute to the onset and progression of PD. Some pesticides have been demonstrated to be associated with PD by many previous studies and experiments, and an increasing number of researchers have paid attention to this area in recent years. This paper aims to explore the knowledge structure, analyze the current research hot spots, and discuss the research trend through screening and summarizing the present literature. Based on 1767 articles from the Web of Science Core Collection and PubMed database, this study carried out the analysis from the keywords, cited references, countries, authors, and some other aspects by using Citespace. The hot topics, valuable articles, and productive authors in this research field could be found after that. To the best of our knowledge, this is the first study to specifically visualize the relationship between pesticide exposure and PD, and forecast research tendency in the future.
    Keywords:  Parkinson's disease; bibliometric; citespace; knowledge mapping; pesticide exposure
  24. Big Data. 2020 Apr;8(2): 89-106
    Wang Y, Zhao Y, Dang W, Zheng J, Dong H.
      This study aims to reveal the evolution of publication hotspots in the field of electronic health records (EHRs) and differences among countries. We applied keyword frequency analysis, keyword co-occurrence analysis, principal component analysis, multidimensional scaling analysis, and visualization technology to compare the high-frequency Medical Subject Heading (MeSH) terms in six countries during the periods 1957-2008 and 2009-2016. After 2009, the number of MeSH terms reflecting information exchange and information mining increased, and various types of evaluations based on EHRs and cohort studies significantly increased. The top 20 MeSH terms between 2009 and 2016 constitute five relatively larger knowledge groups. Thus, we conclude that publication hotspots in EHR field have shifted from issues related to the adoption of EHRs to the utilization of EHRs, and the knowledge structure has become systematic. The publication's focus was different in the six countries, which may relate to their national characteristics.
    Keywords:  bibliometric analysis; electronic health records; electronic medical records; keyword frequency analysis; knowledge network
  25. Rev Lat Am Enfermagem. 2020 ;pii: S0104-11692020000100601. [Epub ahead of print]28 e3257
    Romeiro V, Bullinger M, Marziale MHP, Fegadolli C, Reis RA, Silveira RCCP, Costa-Júnior MLD, Sousa FAEF, Andrade VS, Conacci BJ, Nascimento FK, Santos CBD.
      OBJECTIVE: to map the Brazilian scientific production related to the stages of the methodological process for the use of DISABKIDS® instruments and/or forms adapted to Brazil.METHOD: scoping review, with searches conducted on10 electronic databases, plus Google Scholar and contacts with researchers, without restriction of period or language.
    RESULTS: the mapping identified 90 scientific studies involving 46 instruments. Of these, 11 (23.9%) included the elaboration and/or cultural adaptation of the DISABKIDS® instruments to measure the Quality of Life of children or adolescents with chronic conditions and 35 (76.1%) used the Generic Measures and/or Specific Modules for the semantic validation of other instruments.
    CONCLUSION: this scoping review allowed a comprehensive evaluation of the use of the DISABKIDS® instrument and forms, in relation to the validation of the instrument adapted to Brazil, presenting a positive advance in the scenario with the development of academic/scientific projects in the country, incorporating the method recommended by the literature for the elaboration, cultural adaptation and validation of instruments and for the systematized and standardized recording of the perception and understanding of the target population about the measure of interest, using DISABKIDS® forms adapted for this purpose.
  26. Global Health. 2020 Apr 22. 16(1): 37
    Virani A, Wellstead AM, Howlett M.
      Medical tourism occupies different spaces within national policy frameworks depending on which side of the transnational paradigm countries belong to, and how they seek to leverage it towards their developmental goals. This article draws attention to this policy divide in transnational healthcare through a comparative bibliometric review of policy research on medical tourism in select source (Canada, United States and United Kingdom) and destination countries (Mexico, India, Thailand, Malaysia and Singapore), using a systematic search of the Web of Science (WoS) database and review of grey literature. We assess cross-national differences in policy and policy research on medical tourism against contextual policy landscapes and challenges, and examine the convergence between research and policy. Our findings indicate major disparities in development agendas and national policy concerns, both between and among source and destination countries. Further, we find that research on medical tourism does not always address prevailing policy challenges, just as the policy discourse oftentimes neglects relevant policy research on the subject. Based on our review, we highlight the limited application of theoretical policy paradigms in current medical tourism research and make the case for a comparative policy research agenda for the field.
    Keywords:  Bibliometric analysis; Comparative review; Medical tourism; North-south divide; Policy research; Research-policy gap; Transnational healthcare
  27. J Am Soc Mass Spectrom. 2020 Apr 23.
    Handler DCL, Haynes PA.
      We randomly selected 100 journal articles published in five proteomics journals in 2019, and manually examined each of them against a set of 13 criteria concerning the statistical analyses used, all of which were based on items mentioned in the journals' instructions to authors. This included questions such as whether a pilot study was conducted and whether false discovery rate calculation was employed at either the quantitation or identification stage. These data were then transformed to binary inputs, analysed via machine learning algorithms, and classified accordingly, with the aim of determining if clusters of data existed for specific journals or if certain statistical measures correlated with each other. We applied a variety of classification methods including principal component analysis decomposition, agglomerative clustering, and multinomial and Bernoulli naïve Bayes classification, and found that none of these could readily determine journal identity given extracted statistical features. Logistic regression was useful in determining high correlative potential between statistical features such as false discovery rate criteria and multiple testing corrections methods, but was similarly ineffective at determining correlations between statistical features and specific journals. This meta-analysis highlights that there is a very wide variety of approaches being used in statistical analysis of proteomics data, many of which do not conform to published journal guidelines, and that contrary to implicit assumptions in the field there are no clear correlations between statistical methods and specific journals.