bims-evares Biomed News
on Evaluation of research
Issue of 2020‒03‒08
twenty papers selected by
Thomas Krichel
Open Library Society


  1. PLoS One. 2020 ;15(3): e0228885
    Nazir S, Asif M, Ahmad S, Bukhari F, Afzal MT, Aljuaid H.
      A citation is deemed as a potential parameter to determine linkage between research articles. The parameter has extensively been employed to form multifarious academic aspects like calculating the impact factor of journals, h-Index of researchers, allocate different research grants, find the latest research trends, etc. The current state-of-the-art contends that all citations are not of equal importance. Based on this argument, the current trend in citation classification community categorizes citations into important and non-important reasons. The community has proposed different approaches to extract important citations such as citation count, context-based, metadata, and textual based approaches. The contemporary state-of-the-art in citation classification community ignores significantly potential features that can play a vital role in citation classification. This research presents a novel approach for binary citation classification by exploiting section-wise in-text citation frequencies, similarity score, and overall citation count-based features. The study also introduces machine learning algorithms based novel approach for assigning appropriate weights to the logical sections of research papers. The weights are allocated to the citations with respect to their sections. To perform the classification, we used three classification techniques, Support Vector Machine, Kernel Linear Regression, and Random Forest. The experiment was performed on two annotated benchmark datasets that contain 465 and 311 citation pairs of research articles respectively. The results revealed that the proposed approach attained an improved value of precision (i.e., 0.84 vs 0.72) from contemporary state-of-the-art approach.
    DOI:  https://doi.org/10.1371/journal.pone.0228885
  2. Front Psychiatry. 2020 ;11 27
    Duan L, Zhu G.
      Background: Recently, magnetic resonance imaging (MRI) technology has been widely used to quantitatively analyze brain structure, morphology, and functional activities, as well as to clarify the neuropathological and neurobiological mechanisms of schizophrenia. However, although there have been many relevant results and conclusions, there has been no systematic assessment of this field.Aim: To analyze important areas of research utilizing MRI in studies of schizophrenia and explore major trends and the knowledge structure using bibliometric analysis.
    Methods: Literature related to MRI studies of schizophrenia published in PubMed between January 1, 2004 and December 31, 2018 were retrieved in 5-year increments. The extracted major Medical Subject Headings (MeSH) terms/MeSH subheadings were analyzed quantitatively. Bi-clu-stering analysis, social network analysis (SNA), and strategic diagrams were employed to analyze the word matrix and co-occurrence matrix of high-frequency MeSH terms.
    Results: For the periods of 2004 to 2008, 2009 to 2013, and 2014 to 2018, the number of relevant retrieved publications were 916, 1,344, and 1,512 respectively, showing an overall growth trend. 26, 34, and 36 high-frequency major MeSH terms/MeSH subheadings were extracted in each period, respectively. In line with strategic diagrams, the main undeveloped theme clusters in 2004-2008 were effects of antipsychotics on brain structure and their curative efficacy. These themes were replaced in 2009-2013 by physiopathology mechanisms of schizophrenia, etiology of cognitive disorder, research on default mode network and schizophrenic psychology, and were partially replaced in 2014-2018 by studies of differences in the neurobiological basis for schizophrenia and other mental disorders. Based on SNA, nerve net/physiopathology and psychotic disorder/pathology were considered the emerging hotspots of research in 2009-2013 and 2014-2018.
    Conclusions: MRI studies on schizophrenia were relatively diverse, but the theme clusters derived from each period may reflect the publication trends to some extent. Bibliometric research over a 15-year period may be helpful in depicting the overall scope of research interest and may generate novel ideas for researchers initiating new projects.
    Keywords:  bibliometric analysis; co-occurrence analysis; magnetic resonance imaging; schizophrenia; social network analysis; strategic diagram
    DOI:  https://doi.org/10.3389/fpsyt.2020.00027
  3. J Med Internet Res. 2020 Feb 25. 22(2): e15142
    Gu D, Yang X, Deng S, Liang C, Wang X, Wu J, Guo J.
      BACKGROUND: With the continuous development of the internet and the explosive growth in data, big data technology has emerged. With its ongoing development and application, cloud computing technology provides better data storage and analysis. The development of cloud health care provides a more convenient and effective solution for health. Studying the evolution of knowledge and research hotspots in the field of cloud health care is increasingly important for medical informatics. Scholars in the medical informatics community need to understand the extent of the evolution of and possible trends in cloud health care research to inform their future research.OBJECTIVE: Drawing on the cloud health care literature, this study aimed to describe the development and evolution of research themes in cloud health care through a knowledge map and common word analysis.
    METHODS: A total of 2878 articles about cloud health care was retrieved from the Web of Science database. We used cybermetrics to analyze and visualize the keywords in these articles. We created a knowledge map to show the evolution of cloud health care research. We used co-word analysis to identify the hotspots and their evolution in cloud health care research.
    RESULTS: The evolution and development of cloud health care services are described. In 2007-2009 (Phase I), most scholars used cloud computing in the medical field mainly to reduce costs, and grid computing and cloud computing were the primary technologies. In 2010-2012 (Phase II), the security of cloud systems became of interest to scholars. In 2013-2015 (Phase III), medical informatization enabled big data for health services. In 2016-2017 (Phase IV), machine learning and mobile technologies were introduced to the medical field.
    CONCLUSIONS: Cloud health care research has been rapidly developing worldwide, and technologies used in cloud health research are simultaneously diverging and becoming smarter. Cloud-based mobile health, cloud-based smart health, and the security of cloud health data and systems are three possible trends in the future development of the cloud health care field.
    Keywords:  cloud computing; cloud health care; co-word analysis; cybermetrics; health care informatics
    DOI:  https://doi.org/10.2196/15142
  4. F1000Res. 2019 ;8 237
    Abraham J.
      National culture has been overlooked in discussions related to research productivity and impact owing to individual, socio-political structure, and economic factors. This study shows the relationships between the dimensions of cultural value orientation of the nation and research performance indicators. More than 60 countries were included and Pearson correlation analysis was employed. The variables were taken from Geert Hofstede and Scimago Journal & Country Rank worksheets. This study found that (1) Individualism has significant correlations with the majority of the indicators; (2) Power distance and indulgence correlate with a country's research impact in the form of citation per document; (3) Masculinity, long term orientation, and uncertainty avoidance do not correlate with the indicators. Owing to the fact that the national culture is relatively enduring, countries need to measure their elasticity of hopes and action plans in an effort to boost research productivity and impact, by integrating the national culture in the estimate.
    Keywords:  citations per document; individualism; indulgence; national culture; power distance; research impact; research productivity; self citations
    DOI:  https://doi.org/10.12688/f1000research.18283.3
  5. Neurosurg Focus. 2020 Mar 01. pii: 2019.12.FOCUS19856. [Epub ahead of print]48(3): E20
    Rallo MS, Ashraf O, Jumah F, Gupta G, Nanda A.
      OBJECTIVE: Engagement in research and scholarship is considered a hallmark of neurosurgical training. However, the participation of neurosurgical trainees in this experience has only recently been analyzed and described in the United States, with little, if any, data available regarding the research environment in neurosurgical training programs across the globe. Here, the authors set out to identify requirements for research involvement and to quantify publication rates in leading neurosurgical journals throughout various nations across the globe.METHODS: The first aim was to identify the research requirements set by relevant program-accrediting and/or board-certifying agencies via query of the literature and published guidelines. For the second part of the study, the authors attempted to determine each country's neurosurgical research productivity by quantifying publications in the various large international neurosurgical journals-World Neurosurgery, Journal of Neurosurgery, and Neurosurgery-via a structured search of PubMed.
    RESULTS: Data on neurosurgical training requirements addressing research were available for 54 (28.1%) of 192 countries. Specific research requirements were identified for 39 countries, partial requirements for 8, and no requirements for 7. Surprisingly, the authors observed a trend of increased average research productivity with the absence of designated research requirements, although this finding is not unprecedented in the literature.
    CONCLUSIONS: A variety of countries of various sizes and neurosurgical workforce densities across the globe have instituted research requirements during training and/or prior to board certification in neurosurgery. These requirements range in intensity from 1 publication or presentation to the completion of a thesis or dissertation and occur at various time points throughout training. While these requirements do not correlate directly to national research productivity, they may provide a foundation for developing countries to establish a culture of excellence in research.
    Keywords:  COSECSA = College of Surgeons of East, Central and Southern Africa; JRAAC = Joint Residency Advisory and Accreditation Committee; WFNS = World Federation of Neurosurgical Societies; global neurosurgery; neurosurgery education; neurosurgical trainee research
    DOI:  https://doi.org/10.3171/2019.12.FOCUS19856
  6. Bioinformatics. 2020 Mar 04. pii: btaa132. [Epub ahead of print]
    Chasapi A, Promponas VJ, Ouzounis CA.
      We quantify scientific output for bioinformatics across the world, using a range of bibliometric indices. The most prolific 40 countries generate 96% of all publications in the field, a fact also reflected in the number of citations and the country h-index. Remarkably, 30 of these countries have also been found to generate >98% of the world's top-cited publications. Smaller, productive countries attain a higher status when bibliometric indices are normalized for population size, without altering the overall picture. These 'productivity' patterns can be used for planning local, regional or international initiatives and a more effective development of the field.SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
    DOI:  https://doi.org/10.1093/bioinformatics/btaa132
  7. Nurs Outlook. 2020 Mar 02. pii: S0029-6554(19)30520-2. [Epub ahead of print]
    Bosse JD, Jackman KB, Hughes TL.
      BACKGROUND: Despite multiple federal initiatives and calls to action, nursing literature on the health of sexual and gender minority (SGM) populations remains sparse. Low levels of funding for SGM-focused research may be a factor.PURPOSE: To examine the proportion and focus of National Institute of Nursing Research (NINR)-funded projects that address SGM health, the number and type of publications arising from that funding, and the reach of those publications over time.
    METHODS: NINR-funded grants focused on SGM research and bibliometrics of resultant publications were identified using multiple search strategies in NIH RePORTER and PubMed and Scopus, respectively.
    FINDINGS: Since 1987, NINR has funded 25 projects addressing the health of SGM populations. Pre-doctoral fellowship funding resulted in more publications in nursing journals than research grant funding.
    DISCUSSION: There are clear differences in patterns of funding for fellowships and research grants with corresponding differences in publications and impact on the nursing literature.
    Keywords:  LGBT persons; nursing literature; nursing research; research funding; sexual and gender minorities
    DOI:  https://doi.org/10.1016/j.outlook.2020.01.002
  8. PLoS One. 2020 ;15(3): e0228686
    Swenor BK, Munoz B, Meeks LM.
      Recent data highlights an imbalance in research grant success among groups underrepresented within the biomedical workforce, including racial/ethnic minorities and women. However, there is no data on grant success for researchers with disabilities. For these analyses, aggregate data on self-reported disability status for National Institute on Health (NIH) research grant applicants and awardees was obtained from 2008 to 2018, including disability category: mobility/orthopedic, hearing, visual disabilities, and other disabilities. The percentage of applications and awards, as well as grant success rates (% of applicants receiving awards), by Principal Investigators (PIs) disability status were calculated. Data was desegregated, and logistic models determined trend of applicants reporting disability over time. The percentage of NIH grant applicants with PIs reporting a disability significantly declined from 1.9% in 2008, to 1.2% in 2018 (p<0.001). Data on grant awardees was similar, 1.9% of awards in 2008, declining to 1.2% in 2018 (p<0.001) had PIs reporting a disability. Across all years, the percentage of applications and awards with PIs reporting visual disabilities was lower than the percentage reporting mobility/orthopedic, or hearing disabilities (16.5%, 34.2%, and 37.8% in 2008, respectively). Overall grant success rates differed by disability status (27.2% for those reporting disability vs 29.7% in those reporting no disability, p<0.001). The lowest overall grant success rate was among PIs reporting unknown disability status or who withheld this status (18.6%). These results underscore the underrepresentation of researchers with disabilities among grant applicants and awardees, and indicate lower grant success rates among PIs reporting disabilities.
    DOI:  https://doi.org/10.1371/journal.pone.0228686
  9. Eur Urol Focus. 2020 Feb 26. pii: S2405-4569(20)30058-4. [Epub ahead of print]
    Chandrasekar T, Han TM, Glick L, Leong JY, Teplitsky S, Noorani R, Goldberg H, Klaassen Z, Wallis CJD, Mark JR, Trabulsi EJ, Lallas CD, Gomella LG.
      BACKGROUND: Research productivity among academic urologists is strongly encouraged, but little data are available on productivity metrics within the field.OBJECTIVE: To provide the first comprehensive survey of research productivity among academic urologists in the USA and Canada.
    DESIGN, SETTING, AND PARTICIPANTS: Using the Accreditation Council for Graduate Medical Education, the Canadian Resident Matching Service, and individual program websites, all active accredited urology faculties were identified. For each individual, we collected data on American Urological Association section, title, gender, fellowship training, Scopus H-index, and citations. Comprehensive searches were completed during March-May 2019.
    OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Descriptive statistics for demographic comparisons were performed using analysis of variance for continuous variables and chi-square test for categorical variables. Multivariable logistic regressions were used to identify the predictors of H-index greater than the median.
    RESULTS AND LIMITATIONS: A total of 2214 academic urology faculties (2015 in USA and 199 in Canada) were identified. The median and mean H-indices for the entire cohort of physicians were 11 and 16.1, respectively. On multivariable analysis, physicians in the North Central and Western Sections (vs mid-Atlantic), who were fellowship trained (vs no fellowship training), and of higher academic rank (professor and associate professor vs clinical instructor) were more likely to have H-index values greater than the median. Additionally, female physicians (vs male) were more likely to have H-index values less than the median.
    CONCLUSIONS: This study represents the first comprehensive assessment of research productivity metrics among academic urologists. These represent key benchmarks for trainees considering careers in academics and for practicing physicians gauging their own productivity in relation to their peers.
    PATIENT SUMMARY: In this study, we provide the first comprehensive assessment of research productivity among academic urologists in the USA and Canada. Our results help provide key benchmarks for trainees considering careers in academics and for practicing physicians gauging their own productivity in relation to peers.
    Keywords:  Academic medicine; Academic success; Academic training; Citations; H-index; Professor
    DOI:  https://doi.org/10.1016/j.euf.2020.02.003
  10. J Bras Nefrol. 2020 Feb 21. pii: S0101-28002020005004102. [Epub ahead of print]
    Moura-Neto JA, Riella MC.
      Technological innovations often occur and make an impact on many industries. In academia, Visual Abstracts have been a trend and represent a creative and dynamic way to disseminate scientific knowledge. Although still rare in Brazil, more than 15 journals already use Visual Abstracts worldwide. This brief paper intends to present the concept and discuss the potential effectiveness of this innovative tool.
    DOI:  https://doi.org/10.1590/2175-8239-JBN-2019-0213
  11. Nature. 2020 Mar;579(7797): 8
      
    Keywords:  Funding; Policy; Publishing; Research management
    DOI:  https://doi.org/10.1038/d41586-020-00625-0
  12. Future Cardiol. 2020 Mar 06.
    Shahid I, Motiani V, Siddiqi TJ, Usman MS, Kumar J, Hussain A, Yamani N, Asmi N, Mookadam F.
      Aim: Despite a vast array of research in heart failure (HF), no bibliometric analysis has been conducted for HF. Therefore, we sought to identify in-depth characteristics of 100 most cited publications in HF. Materials & methods: Two independent reviewers searched the Scopus Library Database using a variety of keywords to extract the top 100 articles. Results: Majority (36%) of top 100 cited articles were published between 2001 and 2005. The total number of citations ranged from 6294 to 1003. Females had less than a quarter representation in both first and senior author position. More than three-fourths (86%) of the articles were funded. Conclusion: Our analysis highlights focal areas of research activity in order to guide HF specialists toward impactful research areas.
    Keywords:  HF; bibliometrics; cardiology; citation analysis; citations; funding; gender disparities; heart failure
    DOI:  https://doi.org/10.2217/fca-2019-0016
  13. J Vasc Surg. 2020 Feb 28. pii: S0741-5214(20)30151-8. [Epub ahead of print]
    Carnevale M, Phair J, Batarseh P, LaFontaine S, Koelling E, Koleilat I.
      OBJECTIVE: Previous studies have identified significant gender discrepancies in grant funding, leadership positions, and publication impact in surgical subspecialties. We investigated whether these discrepancies were also present in academic vascular surgery.METHODS: Academic websites from institutions with vascular surgery training programs were queried to identify academic faculty, and leadership positions were noted. H-index, number of citations, and total number of publications were obtained from Scopus and PubMed. Grant funding amounts and awards data were obtained from the National Institutes of Health (NIH) and Society for Vascular Surgery websites. Industry funding amount was obtained from the Centers for Medicare and Medicaid Services website. Nonsurgical physicians and support staff were excluded from this analysis.
    RESULTS: We identified 177 female faculty (18.6%) and 774 male faculty (81.4%). A total of 41 (23.2%) female surgeons held leadership positions within their institutions compared with 254 (32.9%) male surgeons (P = .009). Female surgeons held the rank of assistant professor 50.3% of the time in contrast to 33.9% of men (P < .001). The rank of associate professor was held at similar rates, 25.4% vs 20.7% (P = .187), respectively. Fewer women than men held the full professor rank, 10.7% compared with 26.2% (P < .001). Similarly, women held leadership positions less often than men, including division chief (6.8% vs 13.7%; P < .012) and vice chair of surgery (0% vs 2.2%; P < .047), but held more positions as vice dean of surgery (0.6% vs 0%; P < .037) and chief executive officer (0.6% vs 0%; P < .037). Scientific contributions based on the number of each surgeon's publications were found to be statistically different between men and women. Women had an average of 42.3 publications compared with 64.8 for men (P < .001). Female vascular surgeons were cited an average of 655.2 times, less than half the average citations of their male counterparts with 1387 citations (P < .001). The average H-index was 9.5 for female vascular surgeons compared with 13.7 for male vascular surgeons (P < .001). Correcting for years since initial board certification, women had a higher H-index per year in practice (1.32 vs 1.02; P = .005). Female vascular surgeons were more likely to have received NIH grants than their male colleagues (9.6% vs 4.0%; P = .017). Although substantial, the average value of NIH grants awarded was not statistically significant between men and women, with men on average receiving $915,590.74 ($199,119.00-$2,910,600.00) and women receiving $707,205.35 ($61,612.00-$4,857,220.00; P = .416). There was no difference in the distribution of Society for Vascular Surgery seed grants to women and men since 2007. Industry payments made publicly available according to the Sunshine Act for the year 2018 were also compared, and female vascular surgeons received an average of $2155.28 compared with their male counterparts, who received almost four times as much at $8452.43 (P < .001).
    CONCLUSIONS: Although there is certainly improved representation of women in vascular surgery compared with several decades ago, a discrepancy still persists. Women tend to have more grants than men and receive less in industry payments, but they hold fewer leadership positions, do not publish as frequently, and are cited less than their male counterparts. Further investigation should be aimed at identifying the causes of gender disparity and systemic barriers to gender equity in academic vascular surgery.
    Keywords:  Academic output; Academic rank; Gender disparities; Sunshine payments
    DOI:  https://doi.org/10.1016/j.jvs.2019.12.042
  14. Neurosurg Focus. 2020 Mar 01. pii: 2019.12.FOCUS19825. [Epub ahead of print]48(3): E8
    Yakar F, Hanalioglu S, Sahin B, Egemen E, Dere UA, Kiraz İ, Coskun ME, Kahilogullari G.
      OBJECTIVE: Neurosurgery training programs aim to train specialists. In addition, they are expected to equip the residents with necessary knowledge and skills for academic development. This study aims to gain insights into academic productivity after neurosurgeons graduated from residency training in Turkey.METHODS: An electronic survey was sent to all Turkish Neurosurgical Society members (n = 1662 neurosurgeons) between September and November 2019. The number of participants was 289 (17.4%). Participants were divided into subgroups based on three main factors: training institution type (university hospital [UH] vs training and research hospital [TRH]), training institution annual case volume (low [< 1000 or inadequate cranial/spinal case numbers] vs high [> 1000 and adequate cranial/spinal case numbers]), and training program accreditation status (accredited vs nonaccredited).
    RESULTS: The majority of the participants (64.7%) graduated from the UHs. Those trained at UHs (vs TRHs) and high- (vs low-) volume centers had their dissertations more frequently published in Science Citation Index/Science Citation Index-Expanded journals, gave more oral presentations after residency, had higher h-indices, had higher rates of reviewership for academic journals, and had greater participation in projects with grant support. In addition, graduates of accredited programs reported more PhD degrees than those of nonaccredited programs.
    CONCLUSIONS: Neurosurgeons trained in higher-case-volume, accredited programs, mostly in the UHs, performed better in terms of scientific activities and productivity in Turkey. Strong research emphasis and supportive measures should be instituted to increase academic performance during and after residency training.
    Keywords:  EANS = European Association of Neurological Societies; SCI = Science Citation Index; SCIE = Science Citation Index–Expanded; TNS = Turkish Neurosurgical Society; TRH = training and research hospital; UH = university hospital; academic performance; specialist; survey; training
    DOI:  https://doi.org/10.3171/2019.12.FOCUS19825
  15. Clin Neurol Neurosurg. 2020 Feb 17. pii: S0303-8467(20)30083-4. [Epub ahead of print]192 105740
    Yang C, Wang X, Tang X, Bao X, Wang R.
      OBJECTIVE: Many studies have evaluated the safety and efficacy of stem cells as therapeutic agents for ischemic stroke. We aimed to quantitatively assess the research trends of stem cell therapy for ischemic stroke.PATIENTS AND METHODS: We searched the Web of Science Core Collection to identify relevant publications between 1999 and 2018. We used HistCite to summarize the critical information, including yearly records, authors, countries/regions, and institutions. VOSviewer was applied to map the collaborations between studies. Based on the title and abstract of each publication, MeSH terms were obtained using Medical Text Indexer to demonstrate evolutions of topic hotspots.
    RESULTS: From 1999-2018, there were a total of 3,741 publications exploring the prospect of stem cells in ischemic stroke. Annual publication outputs grew from six records to 366 records. Stroke was the most high-profile journal because of its ranking first on the top productive and co-cited journal lists. The United States of America and China were the two most contributive countries of stem-cell research of ischemic stroke. Researchers were supposed to follow studies from productive institutions because of their consistent and systematic investigations in this field. Neural stem cells and mesenchymal stem cells were the most recognized cells for clinical translation.
    CONCLUSION: With the growth of publications concerning the role of stem cells in ischemic stroke treatment, bibliometrics helps researchers to get insights of academic collaborations, research trends, and hot topics in the study field.
    Keywords:  Bibliometrics; Ischemic stroke; Publications; Stem cells; VOSviewer
    DOI:  https://doi.org/10.1016/j.clineuro.2020.105740
  16. Biomed Khim. 2020 Jan;66(1): 7-17
    Ilgisonis EV, Kiseleva OI, Lisitsa AV, Poverennaya EV, Toporkova MN, Ponomarenko EA.
      This paper proposes a method of comparative analysis of scientific trajectories based on bibliographic profiles. The bibliographic profile ("meshprint") is a list of MeSH terms (key terms used to index articles in the PubMed), indicating the relative frequency of occurrence of each term in the scientist's articles. Comparison of personalized bibliographic profiles can be represented in the form of a semantic network, where the nodes are the names of scientists, and the relationships are proportional to the calculated measures of similarity of bibliographic profiles. The proposed method was used to analyze the semantic network of scientists united by the academic school of the academician A.I. Archakov. The results of the work allowed us to show the relationship between the scientific trajectories of one scientific school and to correlate the results with world trends.
    Keywords:  MeSH; medical subject headings; research trajectory; semantic networks; sociology; text analysis; text-mining
    DOI:  https://doi.org/10.18097/PBMC20206601007
  17. Front Pharmacol. 2020 ;11 37
    Yeung AWK, Tzvetkov NT, Balacheva AA, Georgieva MG, Gan RY, Jozwik A, Pyzel B, Horbańczuk JO, Novellino E, Durazzo A, Lucarini M, Camilli E, Souto EB, Atanasov AG, Santini A.
      The current study provides a comprehensive overview and analysis of the lignan literature. Data for the current study were extracted from the electronic Web of Science Core Collection database via the search string TOPIC = ("lignan*") and processed by the VOSviewer software. The search yielded 10,742 publications. The ratio of original articles to reviews was 14.6:1. Over 80% of the analyzed papers have been published since the year 2000 and nearly 50% since the year 2010. Many of the publications were focused on pharmacology, chemistry, and plant sciences. The United States and Asian countries, such as China, Japan, South Korea, and India, were the most productive producers of lignan publications. Among the 5 most productive institutions was the University of Helsinki in Finland, the country that ranked 9th. Nineteen journals collectively published 3,607 lignan publications and were considered as core journals. Their impact factor did not correlate with the proportion of uncited papers. Highly cited publications usually mentioned phytoestrogen, isoflavone, daidzein, enterodiol, enterolactone, equol, genistein, and isoflavonoid. Cancer (e.g., breast cancer), cardiovascular disease, and antioxidation were the major themes. Clinical trials were estimated to contribute to 0.2-1.1% of the analyzed body of literature, so more of them should be conducted in the future to substantiate the beneficial effects and optimal dose of lignan intake in humans. Moreover, researchers can refer to these findings for future research directions and collaborations.
    Keywords:  VOSviewer; Web of Science; cancer; chemistry; citation analysis; lignans; pharmacology; plant science
    DOI:  https://doi.org/10.3389/fphar.2020.00037
  18. Saudi Med J. 2020 Mar;41(3): 261-266
    Alghamdi MA, Alzahrani RA, Alhashemi HH, Obaid AA, Alghamdi AG, Aldokhi MA, Alghamdi AM, Alghamdi AA, Qanat AS, Jastaniah WA, Alghamdi SM.
      OBJECTIVES: To assess the quality and quantity of Saudi publications in oncology over a 10-year period.METHODS: A systematic PubMed search was conducted between January 2008 and December 2017 to retrieve all Saudi oncology publications. Data about the articles was collected. The level of evidence (LOE) was independently assessed by 2 authors. Two 5-year periods (2008-2012 and 2013-2017) were compared using the relevant parameters. Clinicaltrials.gov was also searched for all oncology trials registered in Saudi Arabia.
    RESULTS: A total of 839 publications met our inclusion criteria. The most common type of research was case series, totaling 32% of all publications. Clinical trials formed less than 2% of the total. The LOE was I, II, III, and IV in 0.3%, 2.1%, 58.4%, and 39.3% of the included publications, respectively. The LOE was the same in the 2 periods. There were more publications in international journals (p=0.004), more international collaborations (p=0.001), and higher journal impact factors (p=0.037) in 2013-2017 than in 2008-2012. Only 76 registered clinical trials were found in the Clinicaltrials.gov registry.
    CONCLUSION: Despite an increase in the number of Saudi publications in the field of oncology over time, the LOE did not change. There were, however, some improvements in the international collaboration and journal impact factor, as well as an increase in the number of studies published in international journals. These observations call for a national strategy to improve oncology research in Saudi Arabia.
    DOI:  https://doi.org/10.15537/smj.2020.3.24912
  19. Arch Iran Med. 2020 Mar 01. 23(3): 181-188
    Masjedi MR, Bazrafshan A, Mosavi Jarrahi A, Mohagheghi MA, Abasahl A, Attarian H, Omranipour R, Afsharpad M.
      BACKGROUND: With the growing rate of tumors, cancer has become one of the most important health concerns in Iran. The urgency with which Iranian researchers and health professionals address this challenge leads to a load of scientific materials.METHODS: To reveal gaps in produced knowledge and suggest future research directions, applying well-validated scientometric tools, we assessed the trends of Iranian published scientific articles and citations in the field of oncology. The inclusion criteria consisted of all oncology-related articles that were data-based, and peer-reviewed; with at least an abstract published in English; and authored by at least one researcher affiliated with Iranian institutions.
    RESULTS: Amongst 5063525 oncology research records indexed in at least one of PubMed, Scopus, or Web of Science Core Collection (WoS) from the start to February 2019, Iranian researches accounted for about 24867 (0.49%). Published articles on all cancers by Iranian researchers had a sharp continuously ascending trend, with the same pattern for citations received. Some important topics such as complementary and alternative medicine (CAM) therapies have been missing and some such as diagnostic and pharmaceutical innovations have been less investigated. The most collaborative country was the United States, while no close collaboration was observed with China that was introduced as the most productive country in the field of oncology over the past decades.
    CONCLUSION: Despite the progressive trend in most oncology fields, some significant practical topics are still missing. Systematic reviews of produced theoretical innovations and translating them to functional knowledge can be of importance to fulfill the mentioned gaps.
    Keywords:  Cancer research; Co-citation analysis; Data visualization; Social network analysis
  20. Front Psychol. 2019 ;10 3072
    Du L, Luo S, Liu G, Wang H, Zheng L, Zhang Y.
      With the estimated high prevalence in the population, the two symptoms of pain and depression threaten the well-being of millions worldwide. Researches of the two symptoms increased year by year. Top-cited studies will help to understand the achievement and guide researchers toward the direction of the research field. However, it is unclear for researches in the field of pain and depression. In this paper, we reviewed the bibliometric characteristics of the top-cited papers about pain and depression. We will review the evidence of authorship, country of origin, institution, journal, study type, and publication year for the 100 top-cited studies on pain and depression based on the Web of Science Core collection. We also highlight studies with the highest cited times. Our study concluded that pain and depression were correlated, which may share common biological pathways.
    Keywords:  bibliometric review; citation; citation analysis; depression; pain; top-cited
    DOI:  https://doi.org/10.3389/fpsyg.2019.03072