bims-evares Biomed News
on Evaluation of research
Issue of 2019‒05‒19
nineteen papers selected by
Thomas Krichel
Open Library Society

  1. Perspect Med Educ. 2019 May 17.
    Thoma B, Chan TM.
      INTRODUCTION: It is often necessary to demonstrate the impact of a research program over time both within and beyond institutions. However, it is difficult to accurately track the publications of research groups over time without significant effort. A simple, scalable, and economical way to track publications from research groups and their metrics would address this challenge.METHODS: Google Scholar automatically tracks the scholarly output and citation counts of individual researchers. We created Google Scholar profiles to track the scholarly productivity of five research groups: an institutional educational research program, a division of emergency medicine, a department of emergency medicine, a national educational scholarship working group, and an international organization dedicated to online education. We added the publications of each group member to their respective group Google Scholar profile and a junior faculty member monitored the citations that were suggested.
    RESULTS: Google Scholar tracked a diverse collection of five research groups over 6-36 months. In addition to having different organizational structures and purposes, the groups varied in size, consisting of 8-60 researchers, and prolificacy, with group citation counts between 1006-58,380 and group h‑indexes ranging from 19-101.
    DISCUSSION: We anticipate that as this innovation becomes better known it will increasingly be adopted by traditional and non-traditional research groups to easily track their productivity and impact. Additional initiatives will be needed to standardize reporting guidelines within and between institutions.
    Keywords:  Google Scholar; Research group; Research impact
  2. Neural Regen Res. 2019 Sep;14(9): 1643-1650
    Liu S, Sun YP, Gao XL, Sui Y.
      Alzheimer's disease is the most common cause of dementia. It is an increasingly serious global health problem and has a significant impact on individuals and society. However, the precise cause of Alzheimer's disease is still unknown. In this study, 11,748 Web-of-Science-indexed manuscripts regarding Alzheimer's disease, all published from 2015 to 2019, and their 693,938 references were analyzed. A document co-citation network map was drawn using CiteSpace software. Research frontiers and development trends were determined by retrieving subject headings with apparent changing word frequency trends, which can be used to forecast future research developments in Alzheimer's disease.
    Keywords:  Alzheimer's disease; CiteSpace; Web of Science; mapping knowledge domain; nerve regeneration; neural regeneration; neuroprotection
  3. Zhongguo Zhong Yao Za Zhi. 2019 Apr;44(8): 1674-1681
    Bu YX, Chen J, Sun Y, Wang YF, Yu LP, Wang B, Tian JH.
      As a new concept in clinical research,the real world research(RWR) has attracted the attention of researchers in the world with its unique advantages. This research mainly analyzed it through visual methods,the specific steps were as follows. Firstly,the Chinese Biomedical Literature Database,China National Knowledge Infrastructure,Wan Fang Database,Medline and EMbase were searched and RWS were included,414 articles in Chinese and 2 158 articles in English were included in this research after layer-bylayer screening; secondly,the main information was extracted and sorted by BICOMS 2 software and generated its co-occurrence matrix; the network relationship diagram was drawn by Net Draw software; the cluster analysis was carried out by using g CLUTO software;finally,this research results show that the numbers of domestic and foreign literatures have shown an overall growth trend,but compared with foreign countries,China's research on the real world started late,the overall strength of research was not as good as abroad;and the domestic and foreign research on the real world was uneven in the region,the research in China was mainly distributed in developed provinces and cities,such as Beijing,Guangdong,Shanghai,etc,and there was a lack of close cooperation between provinces and cities; the foreign research are mainly distributed in developed countries such as the United States,the United Kingdom,Germany,et al; the cooperation between countries was relatively close. And the hotspots and core directions of domestic and foreign research were also different. This research was intended to provide reference for the further research of Chinese researchers through the current description of the themes and capability of the real world research in the world.
    Keywords:  capability of research; real world; theme of research; visualization
  4. Orthopedics. 2019 May 01. 42(3): 137-142
    Lieber AM, Kirchner GJ, Zavras AG, Kerbel YE, Khalsa AS.
      In accordance with the Physician Payment Sunshine Act, all industry payments to physicians in the United States have become publicly available. Previous research has indicated that orthopedic surgeons receive the greatest amount of industry compensation compared with other surgical subspecialists. However, the relationship between this compensation and research productivity is less clear. This study sought to investigate the relationship between consulting fees paid to orthopedic surgeons and academic productivity. Using the Centers for Medicare & Medicaid Services Open Payments Database, this study identified 2555 orthopedic surgeons who received at least one industry consulting fee in 2015. Physicians who received total consulting fees of at least $20,000 (US) were stratified into the high payment group. The number of publications and the h-index for each physician were used as metrics of scholarly impact. Mean publication number and h-index for the high payment group were compared with all other physicians in the sample using an independent-samples t test. A total of 2555 orthopedic surgeons received consulting payments totaling $62,323,143 in 2015. The mean consulting payment was $24,393 (SD, $45,465). The publication number was greater for the high payment group (mean, 61.6; SD, 135.6) compared with all other physicians in the sample (mean, 36.1; SD, 95.6). Additionally, the mean h-index for the high payment group was 13.7 (SD, 14.3) compared with 10.0 (SD, 11.6) for all other orthopedic surgeons. These findings indicate that the orthopedic surgeons who receive more in industry consulting fees are also those who contribute most substantially to the body of orthopedic literature. [Orthopedics. 2019; 42(3):137-142.].
  5. Subst Abuse Treat Prev Policy. 2019 May 17. 14(1): 21
    Tran BX, Moir M, Latkin CA, Hall BJ, Nguyen CT, Ha GH, Nguyen NB, Ho CSH, Ho RCM.
      BACKGROUND: Globally, substance use disorders are prevalent and remain an intractable public health problem for health care systems. This study aims to provide a global picture of substance use disorders research.METHODS: The Web of Science platform was used to perform a cross-sectional analysis of scientific articles on substance use disorders and treatment. Characteristics of publication volume, impact, growth, authors, institutions, countries, and journals were examined using descriptive analysis and network visualization graphs.
    RESULTS: Thirteen thousand six hundred eighty-five papers related to illicit drugs (5403), tobacco (4469), and alcohol (2137) use disorders and treatment were published between 1971 and 2017. The number of publications on Mindfulness and Digital medicine topics had the highest increase with more than 300% since 2003-2007 despite later presence than other methods. The number of papers on other non-pharmaceutical therapies (behavioral therapy, cognitive behavioral therapy, skills training or motivational interviewing) grew gradually, however, the growth rate was lower every 5-year period. The United States is the substance use disorder research hub of the world with the highest volume of publications (8232 or 60.2%) and total citations (252,935 or 65.2%), number of prolific authors (25 of top 30 or 83%) and institutions (24 of top 26 or 92%), formed the most international research partnerships (with 96 distinct countries). The international collaboration followed a pattern based on geographic proximity and cultural similarity.
    CONCLUSIONS: This study offers a comprehensive picture of the global trend of publications of substance use disorder. Findings suggest a need for research policy that supports the examination of interventions that culturally adhere to different local contexts to address substance use disorder in communities.
    Keywords:  Alcohol; Bibliometric analysis; Global, mapping; Smoking; Substance abuse treatment; Substance use disorder
  6. J Telemed Telecare. 2019 May 12. 1357633X19846252
    Drosatos G, Kaldoudi E.
      INTRODUCTION: eHealth emerged as an interdisciplinary research area about 70 years ago. This study employs probabilistic techniques to semantically analyse scientific literature related to the field of eHealth in order to identify topics and trends and discuss their comparative evolution.METHODS: Authors collected titles and abstracts of published literature on eHealth as indexed in PubMed. Basic statistical and bibliometric techniques were applied to overall describe the collected corpus; Latent Dirichlet Allocation was employed for unsupervised topics identification; topics trends analysis was performed, and correlation graphs were plotted were relevant.
    RESULTS: A total of 30,425 records on eHealth were retrieved from PubMed (all records till 31 December 2017, search on 8 May 2018) and 23,988 of these were included to the study corpus. eHealth domain shows a growth higher than the growth of the entire PubMed corpus, with a mean increase of eHealth corpus proportion of about 7% per year for the last 20 years. Probabilistic topics modelling identified 100 meaningful topics, which were organised by the authors in nine different categories: general; service model; disease; medical specialty; behaviour and lifestyle; education; technology; evaluation; and regulatory issues.
    DISCUSSION: Trends analysis shows a continuous shift in focus. Early emphasis on medical image transmission and system integration has been replaced by increased focus on standards, wearables and sensor devices, now giving way to mobile applications, social media and data analytics. Attention on disease is also shifting, from initial popularity of surgery, trauma and acute heart disease, to the emergence of chronic disease support, and the recent attention to cancer, infectious disease, mental disorders, paediatrics and perinatal care; most interestingly the current swift increase is in research related to lifestyle and behaviour change. The steady growth of all topics related to assessment and various systematic evaluation techniques indicates a maturing research field that moves towards real world application.
    Keywords:  Latent Dirichlet Allocation; eHealth; topic modelling; trends analysis
  7. Rep Pract Oncol Radiother. 2019 May-Jun;24(3):24(3): 294-297
    McClelland Iii S, Mitin T, Nabavizadeh N, Fuller CD, Thomas CR, Jaboin JJ.
      Introduction: The Hirsch index (h-index) evaluates citation-based scholarly activity, but has limited ability to acknowledge those publishing a smaller number of manuscripts with exceedingly high citations. The g-index addresses this limitation by assessing the largest number of manuscripts (g) by an author cited at least (g × g) times, but has yet to be applied to radiation oncology resident productivity.Methods: A list of recent radiation oncology resident graduates (comprising 86% of the 2016 graduating class) and their post-residency career choice was compiled. The Scopus bibliometric citation database was searched to collect and calculate g-index data for each resident.
    Results: The mean g-index score for all resident graduates was 7.16. Residents with a PhD had significantly higher g-index scores (11.97 versus 5.80; p < 0.01), while there was no statistically significant difference in g-index scores between male and female residents. Residents choosing academic careers had higher g-index scores than those choosing private practice (9.47 versus 4.99; p < 0.01). Programs graduating at least three residents produced significantly higher g-index scores/resident than those graduating two residents, and while comprising only 25% of programs and 45% of residents, produced 60% of academic careers (p < 0.02).
    Conclusion: Radiation oncology resident graduates published on average a minimum of seven manuscripts cited at least 49 times. PhD-degree graduates had significantly higher g-index scores, as did residents choosing academic over private practice careers. There was no significant gender-related difference in g-index score regardless of career choice. The majority of academic careers are produced from programs graduating at least three residents.
    Keywords:  Academic radiation oncology; Private practice radiation oncology; Radiation oncology residency graduates; Residency program size; g-Index
  8. Nanoscale Res Lett. 2019 May 16. 14(1): 164
    Ale Ebrahim S, Ashtari A, Zamani Pedram M, Ale Ebrahim N.
      This bibliometric study investigated the public trends in the fields of nanoparticles which is limited to drug delivery and magnetic nanoparticles' literature published from 1980 to October 2017. The data were collected from the Web of Science Core Collections, and a network analysis of research outputs was carried out to analyse the research trends in the nanoparticles literature. Nanoparticles and its applications are progressing in recent years. The results show that documents in the field of nanoparticles in chemistry and material science have improved in citation rate, as the authors were researching in multidisciplinary zones. Top-cited documents are mainly focusing on drug delivery, magnetic nanoparticles and iron oxide nanoparticles which are also the top research keywords in all papers published. Top-cited papers are mostly published in Biomaterials journal which so far has published 12% of top-cited articles. Although research areas such as contrast agents, quantum dots, and nanocrystals are not considered as the top-ranked keywords in all documents, these keywords received noticeable citations. The trends of publications on drug delivery and magnetic nanoparticles give a general view on future research and identify potential opportunities and challenges.
    Keywords:  Bibliometrics; Biomedical and medical applications; Drug delivery to the brain/cell; Magnetic nanoparticles; Nanotechnology; Research productivity
  9. Turk J Anaesthesiol Reanim. 2019 Apr;47(2): 151-157
    Çekmecelioğlu BT, Kozanhan B, Eren G.
      Objective: The most widely accepted parameter in evaluating the quality of research presented at scientific congresses is the success of publishing that research in a peer-reviewed journal. There are limited data in the literature about the publishing rates of abstracts orally presented at national congresses of the Turkish Society of Anaesthesiology and Reanimation (TARD) in scientific journals. The aim of the present study was to investigate the literary contribution of oral presentations at the TARD Congresses (TARK) and to present proposals for future congresses with detailed evaluation of the literature.Methods: Overall, 319 orally presented abstracts at the TARK between October 2011 and October 2014 have been reviewed in the PubMed and Google Scholar databases. Abstracts were evaluated with respect to the institution of the principal author, type of research, publication status in scientific journal, type of publication, year of publication, rate of citation, order of authors and changes in title.
    Results: The distributions of investigated papers were as follows: 73.1% clinical research, 21.9% experimental research, 2.5% case presentations and 2.5% survey studies. Moreover, 57.7% of the abstracts had authors from universities, 16% from research-training hospitals and 26.3% from mixed institutions. Further, 42.3% of the abstracts were published as articles in a scientific journal, 65.9% of the manuscripts were published in the Science Citation Index Expanded (SCIE) indexed, 8.1% in non-SCIE indexed international journals and 25.9% in national journals. There was no statistically significant difference between institution from which publications were sent and the index status of the journal (p=0.068). The average publication time of the abstracts was 15.01±12.26 months.
    Conclusion: The publication rate of abstracts orally presented at the TARK between October 2011 and October 2014 is 42.3%, which is in accordance with other international studies. This indicates that the reports in the congresses were assessed by the jury according to international selection criteria and meticulously scored. The majority of the abstracts were published in journals that are listed in SCIE, indicating a quantitative data regarding the scientific quality of research in anaesthesiology.
    Keywords:  Congress; manuscript; publication; research
  10. Pediatr Transplant. 2019 May 13. e13455
    Rickard M, Hannick JH, Fernandez N, Koyle MA, MacMurdo K, Lorenzo AJ.
      INTRODUCTION: Pediatric renal transplantation has been heavily published since the 1950s. Herein, we describe the bibliometrics and impact of the 200 most-cited pediatric renal transplantation manuscripts.METHODS: We identified pediatric renal transplantation publications from 1900 onwards. Year, citations, h-index, geographic origin, impact factor, topic, and design of the 200 top-cited papers were extracted. Impact index was calculated, adjusting for citation volume and time since publication.
    RESULTS: Of the top 200 papers, mean citation count was 80 ± 40, impact factor 3.9 ± 3.7, h-index 35 ± 20, and impact index 25 ± 13. Studies were mostly retrospective (31%) or observational (32%). Most papers originated from the United States (58%), Germany (9%), and Italy (6%), which did not correlate with citation counts. Transplantation (18%), Pediatric Nephrology (16%), and American Journal of Transplantation (11%) had the highest publication volume, which did not correlate with citation count. The main topics were medical renal disease, drug monitoring, compliance, and viruses. Most of the top-cited papers (179; 90%) were published after 1991. The difference in the number of times cited between papers published before and after 1991 was insignificant (75 ± 24 vs 80 ± 42; P = 0.59). There was a difference in impact index for the same period (48 ± 15 vs 22 ± 10; P < 0.01).
    CONCLUSIONS: The most-cited papers were concentrated in three journals, but the top three cited papers were published elsewhere. Recent publications were more cited with a higher impact than older papers. Despite the importance of surgery in transplantation, there is a paucity of high-impact papers on this topic.
    Keywords:  bibliometrics; citation mapping; kidney transplantation; pediatrics
  11. Rev Panam Salud Publica. 2018 ;42 e77
    Kristensen-Cabrera AI, Cuervo LG.
      This report contributes towards the monitoring and evaluation of the Pan American Health Organization/World Health Organization (PAHO/WHO) Policy on Research for Health (CD49/10), specifically, how it has been used by Member States and how it has influenced their policies, strategies, research, and relevant stakeholders. This cross-sectional study examined the frequency, method of utilization, region of interest or "scope," and rationale behind citing the Policy in PAHO/WHO documents, databases, government websites, and internal documents. The extent of utilization was measured through an ordinal scale; the country or region of interest was systematically extracted. Of the 993 documents that were identified through the search strategy, 95 met the inclusion criteria. There was a significant relationship between type of document and scope (χ2 = 69.5; P < 0.001), with web pages and scientific articles covering the Americas more frequently mentioning the Policy. The Policy was most often used at the country level in government documents and at the regional level in webpages and journal articles. Although the Policy has been utilized by several countries, many countries have yet to integrate it with their national health research initiatives. Additional research should focus on understanding why Policy utilization differs among countries. To promote better cohesion across sectors and levels of governance, researchers and policymakers should seize opportunities to integrate the Policy with the research process, research governance, and policy development. The protocol developed for this study can be applied to similar analyses of other PAHO/WHO policies to gain a greater understanding of their influence.
    Keywords:  Americas; Health policy; Pan American Health Organization; World Health Organization; health services research
  12. World Neurosurg. 2019 May 13. pii: S1878-8750(19)31312-9. [Epub ahead of print]
    Waqas M, Shakir HJ, Shallwani H, Beecher JS, Rangel-Castilla L, Siddiqui AH, Levy EI.
      BACKGROUND: Concerns existed that neurosurgery might fail to lead the field of endovascular surgical neuroradiology (ESN), as other specialties were allowed to train and practice ESN. This study aimed to assess the current breakdown of specialties and their relative academic productivity in accredited ESN fellowship programs.METHODS: A list of fellowship programs was obtained from the Accreditation Council for Graduate Medical Education and Committee on Advanced Subspecialty Training directories. Primary specialty (i.e., residency) training for each faculty member in these programs was determined using information provided by the programs. A bibliometric search was performed for each member using Web of Science (Clarivate Analytics, Philadelphia PA). Cumulative and ESN-specific h indices were calculated; h indices were compared between each specialty group and between international medical graduates (IMGs) and United States medical graduates (USMGs), regardless of specialty training.
    RESULTS: Thirty-one ESN fellowship programs with 88 faculty members were included. Neurosurgeons constituted 61.4% (n=54) of the total ESN faculty, followed by radiologists with 30.7% (n=27), and neurologists with 7.9% (n=7). The mean ESN-specific h index for neurosurgery-trained ESN faculty was 16.2±14.6 compared to 14.4±10.9 for radiologists and 13.0±12.6 for neurologists (p=0.76). There were 12 IMGs and 76 USMGs. The mean ESN-specific h index was higher for IMGs than USMGs, 24.7±14.3 versus 14.0±12.7 (p=0.008), respectively.
    CONCLUSION: Neurosurgery is leading the ESN field in numbers; however, the h index is not significantly different among ESN faculty based on primary training. The number of IMGs is relatively small, yet IMGs have significantly higher mean h indices.
    Keywords:  academic productivity; bibliometrics; citation analysis; h index; neuroendovascular surgery; neurointervention
  13. Neurocrit Care. 2019 May 13.
    Ramos MB, Koterba E, Rosi Júnior J, Teixeira MJ, Figueiredo EG.
      Bibliometric analyses may indicate the most active journals, authors, countries, institutions and specialties by evaluating the most cited articles in a given research field. To the authors' knowledge, there is no bibliometric analysis regarding neurocritical care research. Thus, the aim of this study is to analyze and to provide a scope of the current scientific production in this area. The 100 most cited articles in the neurocritical care research were retrieved from the research "(neurocritical) AND (care)" in the Scopus database. The variables collected and included in this analysis were: number of citations, article title, first author's name, year and journal of publication and its impact factor (IF), specialty, affiliation and country of the corresponding author at the time of publication, and category of the article. Also, these variables were assessed for primary research only. The articles were published in 34 different journals from 1995 to 2017, with a mean citation number of 109.36, ranging from 44 to 540. Neurocritical Care (23 articles in top 100 and 2190 citations, IF = 3.163) and Critical Care Medicine (20 articles and 2896 citations in top 100, IF = 6.630) were the journals with the greatest number of articles and citations, respectively. Neurocritical Care also had the highest number of primary research papers (15 articles, accounting for 850 citations). Excepting one article from Asia (Singapore) and one from Oceania (Australia), all the other 98 papers were from North America (67) or Europe (31). United States was the country with most articles (60, 35 primary research) and citations (6115) among the top 100. Columbia University (11 articles, being 7 primary research, and 915 citations) was the institution with the highest number of articles and primary research articles in top 100, whereas University of Heidelberg (6 articles and 1220 citations) was the most cited institution. Neurology was the specialty with the greatest number of publications in top 100 and the most cited one (57 articles and 5983 citations). The first author with the greatest number of publications as well as primary research articles was A. I. Qureshi (5 articles, being 4 primary research, and 660 citations), while the most cited was K. H. Polderman (2 articles and 749 citations). Fifty-nine publications were primary and 41 secondary research. Among primary research, treatment/management was the most frequent and most cited topics (33 articles and 4172 citations). To the authors' knowledge, this is the first bibliometric analysis regarding neurocritical care research. Our findings suggest that the neurocritical care research field is more prominent in North America and Europe, more frequently published in specific critical care journals and after 1994. The most discussed topic was related to treatment and/or management within neurocritical care.
    Keywords:  Anesthesiology; Bibliometric analysis; Critical care; Intensive care units; Neurology; Neurosurgery
  14. PeerJ. 2019 ;7 e6825
    Zhang C, Feng X, Wang C, Liu D, He C, Xu W.
      Objectives: Rheumatology-related diseases remain a significant burden worldwide. However, little is known about the comparative status of rheumatology research between Mainland China (MC) and the world's leading countries. The aim of this study is to compare the quantity and quality of research output in the field of rheumatology that were written by researchers from MC, the USA, the UK, the Netherlands and France.Methods: Between 2007 and 2017, all articles published in 30 rheumatology journals were identified via Science Citation Index Expanded database. The number of total and annual articles, article types (randomized controlled trials (RCTs), reviews, case reports, clinical trials and meta-analysis), impact factor (IF), citations, h-index and articles in the high-impact journals were collected for quantity and quality comparisons. The correlation of socioeconomic factors and annual publications was also analyzed.
    Results: From 2007 to 2017, there were 53,439 articles published in rheumatology journals, of which researchers from the USA published 13,391 articles, followed by the UK, the Netherlands, France and MC with 6,179, 4,310, 4,066 and 2,898 articles, respectively. Publications from MC represented the ninth, but the number is growing rapidly. For total and average citations, MC still lags behind the other four countries in the study. Similar trends were observed in average IF, h-index and articles in the high-impact journals. In terms of article types, the USA occupies the dominant place, except for meta-analysis. The annual numbers of articles from MC and the USA were positively correlated with gross domestic product (p < 0.05).
    Conclusions: The USA has played predominant role in rheumatology research for the last 11 years. The annual number of published articles from MC has increased notably from 2007 to 2017. Although MC has made progress in the number of published articles over the past decade, it still lags far behind the highly developed countries in most bibliometric indicators. Thus, the general quality of publications from MC needs further improvement.
    Keywords:  Bibliometrics; Rheumatology; Science citation index expanded
  15. Am Psychol. 2019 May 13.
    Odic D, Wojcik EH.
      Women are notably underrepresented in the academic sciences. Psychology is a pertinent case study of gender inequality in science, because women make up over three quarters of undergraduate and graduate students but only a third of all full professors. Here, publication records from 125 high-impact, peer-reviewed psychology journals are analyzed to describe nuanced patterns about how men and women contribute to research psychology. To determine gender, we classified over 750,000 authors on 200,000 unique publications by comparing the 1st name of each author to openly available census data. The data replicate previous reports of publication and citation gender gaps in psychology and significantly extend these results by showing that these gaps are persistent across subdiscipline and time but are mediated by various contextual factors. For example, although the size of the publication and citation gaps are not explained by the university affiliation of the authors' and frequency of coauthorship, the gaps are larger in high-impact journals and at the last-author position. These patterns have remained largely unchanged since at least 2003. These results provide a detailed look at the variety of factors contributing to the differences in how men and women publish in research psychology and provide free and openly available tools for assessing publication and citation differences across time, journals, and other academic disciplines. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
  16. Medicine (Baltimore). 2019 May;98(20): e15718
    Chen X, Yang K, Xu Y, Li K.
      OBJECTIVES: The use of citation analysis to identify the first 100 papers in inflammatory bowel disease (IBD) provides unique insights into advances in disease understanding and subsequent follow-up treatment innovations over time.METHODS: The Thomson Reuters Web of Science database with the search terms "inflammatory bowel disease" or "Crohn disease" or "ulcerative colitis" or "colitis" was used to identify all English language full manuscripts for the study. Title, first and senior authors, institution and department of first author, journal, country of origin, year, and topic of each manuscript were analyzed.
    RESULTS: The top 100 manuscripts were published between 1955 and 2013. 224,809 eligible papers were returned and the median (range) citation number was 1028.5 (719-3957). The country and year with the greatest number of publications were the USA (n = 47), and 2007 (n = 11). Gastroenterology published the highest number of papers (n = 18, 21,083 citations) and The New England Journal of Medicine had the most citations (n = 13, 25,035 citations).
    CONCLUSIONS: This highly cited list of papers identifies the subjects and authors who have had the greatest impact on IBD research in the last decades, which serves as a reference for researchers and clinicians "highly citable" manuscripts.
  17. Med Sci Monit. 2019 May 12. 25 3520-3536
    Cai A, Suckau J, Arkudas A, Beier JP, Momeni A, Horch RE.
      Post-mastectomy autologous reconstruction with abdominal tissue has evolved over the past 4 decades and is a common reconstructive modality today. To gain more insight into this evolution, we performed an analysis of the 100 most commonly cited articles focusing on autologous breast reconstruction with transverse rectus abdominis musculocutaneous (TRAM) or deep inferior epigastric perforator (DIEP) flaps. A review of the ISI Web of Knowledge database was performed. Only peer-reviewed articles in English were included for analysis. Articles were ranked by their total citations as well as citation density (citations divided by years since publication). The 100 most cited articles were analyzed by their bibliographic parameters. The 100 most cited articles were published in 12 journals. The highest ranked plastic surgery journal published almost 2/3 of the articles. All articles were published within 23 years and marked the "rising age" of autologous breast reconstruction with TRAM and DIEP flaps. The focus of clinical research changed over this time period and ranged from innovations in surgical technique to analysis of clinical outcomes, comparative analyses with other reconstructive modalities, timing of reconstruction, and preoperative diagnostic workup, as well as cost-effectiveness analyses. This literature review illustrates the dramatic change that has occurred subsequent to introduction of abdominal flaps for breast reconstruction. While the use of abdominal flaps has become widely accepted for breast reconstruction, many questions remain unanswered, thus highlighting the need for ongoing clinical investigation.
  18. Expert Rev Med Devices. 2019 May 16.
    Lucena MFG, Teixeira PEP, Bonin Pinto C, Fregni F.
      INTRODUCTION: Transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are noninvasive neuromodulation techniques used as therapeutic and research tools for several neuropsychiatric conditions. Given the exponential scientific growth of this field we aimed to systematically review the most cited clinical trials using TMS or tDCS. Areas covered: A de-novo keyword search strategy identified and characterized the 100 most-cited trials. Total citation count for the most cited trials was 13,204. Articles were published between 2008 and 2014 in 50 different journals with a median impact factor of 6.52 (IQR 3.37). Almost half of the top cited papers were investigating mechanisms of action in healthy subjects. Most studies were feasibility trials and only 5 were pivotal trials, including the ones used for recent FDA approval. Seven articles were interlinked with another article by at least 25 citations and eight authors had collaborated with at least one other author. Expert Commentary: Although there has been a significant increase in interest for rTMS and tDCS, most of the cited clinical trials are still small feasibility studies, what reinforced the need for more robust clinical trials (larger samples sizes and effects sizes) to better define clinical effectiveness.
    Keywords:  bibliometrics; citation analysis; neuromodulation; neurosciences; noninvasive brain stimulation; transcranial direct current stimulation; transcranial magnetic stimulation
  19. PLoS One. 2019 ;14(5): e0216125
    Devezer B, Nardin LG, Baumgaertner B, Buzbas EO.
      Consistent confirmations obtained independently of each other lend credibility to a scientific result. We refer to results satisfying this consistency as reproducible and assume that reproducibility is a desirable property of scientific discovery. Yet seemingly science also progresses despite irreproducible results, indicating that the relationship between reproducibility and other desirable properties of scientific discovery is not well understood. These properties include early discovery of truth, persistence on truth once it is discovered, and time spent on truth in a long-term scientific inquiry. We build a mathematical model of scientific discovery that presents a viable framework to study its desirable properties including reproducibility. In this framework, we assume that scientists adopt a model-centric approach to discover the true model generating data in a stochastic process of scientific discovery. We analyze the properties of this process using Markov chain theory, Monte Carlo methods, and agent-based modeling. We show that the scientific process may not converge to truth even if scientific results are reproducible and that irreproducible results do not necessarily imply untrue results. The proportion of different research strategies represented in the scientific population, scientists' choice of methodology, the complexity of truth, and the strength of signal contribute to this counter-intuitive finding. Important insights include that innovative research speeds up the discovery of scientific truth by facilitating the exploration of model space and epistemic diversity optimizes across desirable properties of scientific discovery.