bims-climfi Biomed News
on Cerebellar cortical circuitry
Issue of 2023‒01‒29
two papers selected by
Jun Maruta
Mount Sinai Health System

  1. Cerebellum. 2023 Jan 24.
      The present Cerebellar Classic highlights the experimental work of the Swedish neurophysiologist Olov Oscarsson (1931-1996) on the afferent innervation of the cerebellum by axons emanating from neurons in the spinal cord and the inferior olive. Historically, the schemes of cerebellar division had been principally based on the external morphology of lobules and fissures. However, the macroscopic anatomical division of the cerebellum does not coincide with its pattern of functional organization. By defining a system of longitudinal somatotopy, Oscarsson contributed to the much needed plan of cerebellar division that correlates experimental information on axonal connections with physiology. His contribution has ultimately led to the currently accepted microzonal modular scheme of cerebellar corticonuclear microcomplexes.
    Keywords:  Cerebellar afferent innervation; Cerebellar corticonuclear microcomplexes; Cerebellar longitudinal somatotopy; Cerebellar microzones
  2. Cerebellum. 2023 Jan 24.
      Olov Oscarsson's review on the functional organization of spinocerebellar paths is a prime demonstration of the great skills and huge knowledge base of the electrophysiologists of his era working on communication systems in the brain. Oscarsson describes and characterizes in detail no less than ten different communication lines between the spinal cord and the cerebellum. As such, his work proved to be a highly fertile basis for ongoing physiological and anatomical research. However, even after 50 years of continuing cerebellar research, many questions are still open and even care must be taken that the differentiation in spinocerebellar paths, so carefully demonstrated by Oscarsson, is not lost in present-day research.
    Keywords:  Cerebellar afferents; Climbing fibers; Inferior olive; Mossy fibers; Spino-olivocerebellar