bims-evares Biomed News
on Evaluation of research
Issue of 2023‒05‒07
forty-four papers selected by
Thomas Krichel
Open Library Society


  1. Front Bioeng Biotechnol. 2023 ;11 1152067
      Background: Cardiovascular and cerebrovascular diseases are major global health problems, and the main cause is atherosclerosis. Recently, molecular imaging has been widely employed in the diagnosis and therapeutic applications of a variety of diseases, including atherosclerosis. Substantive facts have announced that molecular imaging has broad prospects in the early diagnosis and targeted treatment of atherosclerosis. Objective: We conducted a scientometric analysis of the scientific publications over the past 23 years on molecular imaging research in atherosclerosis, so as to identify the key progress, hotspots, and emerging trends. Methods: Original research and reviews regarding molecular imaging in atherosclerosis were retrieved from the Web of Science Core Collection database. Microsoft Excel 2021 was used to analyze the main findings. CiteSpace, VOSviewer, and a scientometric online platform were used to perform visualization analysis of the co-citation of journals and references, co-occurrence of keywords, and collaboration between countries/regions, institutions, and authors. Results: A total of 1755 publications were finally included, which were published by 795 authors in 443 institutions from 59 countries/regions. The United States was the top country in terms of the number and centrality of publications in this domain, with 810 papers and a centrality of 0.38, and Harvard University published the largest number of articles (182). Fayad, ZA was the most productive author, with 73 papers, while LIBBY P had the most co-citations (493). CIRCULATION was the top co-cited journal with a frequency of 1,411, followed by ARTERIOSCL THROM VAS (1,128). The co-citation references analysis identified eight clusters with a well-structured network (Q = 0.6439) and highly convincing clustering (S = 0.8865). All the studies calculated by keyword co-occurrence were divided into five clusters: "nanoparticle," "magnetic resonance imaging," "inflammation," "positron emission tomography," and "ultrasonography". Hot topics mainly focused on cardiovascular disease, contrast media, macrophage, vulnerable plaque, and microbubbles. Sodium fluoride ⁃PET, targeted drug delivery, OCT, photoacoustic imaging, ROS, and oxidative stress were identified as the potential trends. Conclusion: Molecular imaging research in atherosclerosis has attracted extensive attention in academia, while the challenges of clinical transformation faced in this field have been described in this review. The findings of the present research can inform funding agencies and researchers toward future directions.
    Keywords:  VOSviewer; atherosclerosis; citespace 6; molecular imaging; scientometric
    DOI:  https://doi.org/10.3389/fbioe.2023.1152067
  2. J Immunol Res. 2023 ;2023 4835710
      Background: Idiopathic pulmonary fibrosis (IPF) is a disease with significant morbidity, progressive deterioration of lung function till death, and lack of effective treatment options. This study aims to explore the global research trends in IPF and immune response to predict the research hotspot in the future. Materials and methods. All related publications on IPF and immune response since the establishment of diagnostic criteria for IPF were retrieved using the Web of Science (WOS) database. VOSviewer, GraphPad Prism 6, CiteSpace version 5.6. R5 64-bit, and a bibliometrics online platform were used to extract and analyze the trends in relevant fields.Results: From March 1, 2000, to September 30, 2022, a total of 658 articles with 25,126 citations met the inclusion criteria. The United States ranked first in number of publications (n = 217), number of citations (n = 14,745), and H-index (62). China ranked second in publications (n = 124) and seventh and fifth for citation frequency and H-index, respectively. The American Journal of Respiratory and Critical Care Medicine (impact factor = 30.528) published the most articles in the field. The author Kaminski N. from the United States was the most influential author with 26 publications and an H-index of 24. Among the 52 keywords that co-occurred at least 20 times, the main keywords were concentrated in "Inflammation related" and "Biomarker related" clusters. "biomarker" (AAY 2018.64, 25 times) was a newly emerged keyword.
    Conclusions: The United States has an unequivocal advantage in IPF and immunization, but China shows a faster developing trend. The American Journal of Respiratory and Critical Care Medicine should be prioritized for leading articles. This study indicates that exploration of ideal immune-related biomarkers to provide evidence for the clinical work of IPF might be a hotspot in the near future.
    DOI:  https://doi.org/10.1155/2023/4835710
  3. Front Public Health. 2023 ;11 1128008
      Objective: The objective of this study is to conduct a comprehensive bibliometric analysis to identify and evaluate global trends in diabetic retinopathy (DR) research and visualize the focus and frontiers of this field.Methods: Diabetic retinopathy-related publications from the establishment of the Web of Science (WOS) through 1 November 2022 were retrieved for qualitative and quantitative analyses. This study analyzed annual publication counts, prolific countries, institutions, journals, and the top 10 most cited literature. The findings were presented through descriptive statistics. VOSviewer 1.6.17 was used to exhibit keywords with high frequency and national cooperation networks, while CiteSpace 5.5.R2 displayed the timeline and burst keywords for each term.
    Results: A total of 10,709 references were analyzed, and the number of publications continuously increased over the investigated period. America had the highest h-index and citation frequency, contributing to the most influence. China was the most prolific country, producing 3,168 articles. The University of London had the highest productivity. The top three productive journals were from America, and Investigative Ophthalmology Visual Science had the highest number of publications. The article from Gulshan et al. (2016; co-citation counts, 2,897) served as the representative and symbolic reference. The main research topics in this area were incidence, pathogenesis, treatment, and artificial intelligence (AI). Deep learning, models, biomarkers, and optical coherence tomography angiography (OCTA) of DR were frontier hotspots.
    Conclusion: Bibliometric analysis in this study provided valuable insights into global trends in DR research frontiers. Four key study directions and three research frontiers were extracted from the extensive DR-related literature. As the incidence of DR continues to increase, DR prevention and treatment have become a pressing public health concern and a significant area of research interest. In addition, the development of AI technologies and telemedicine has emerged as promising research frontiers for balancing the number of doctors and patients.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; diabetic retinopathy; public health
    DOI:  https://doi.org/10.3389/fpubh.2023.1128008
  4. Helicobacter. 2023 May 03. e12986
      BACKGROUND: Recently, numerous publications on Helicobacter pylori (H. pylori) have been published, but bibliometric analyses on this research field are scarce. To address this gap, we conducted a bibliometric analysis to provide a comprehensive overview and to explore the current research states and hotspots in this field.MATERIALS AND METHODS: Publications on H. pylori from 2002 to 2021 were retrieved from the Web of Science Core Collection database (WoSCC). Trends in publications and citations were analyzed using Excel 2021. VOSviewer and Citespace were used to perform bibliometrics analysis.
    RESULTS: 36,266 publications on H. pylori were retrieved from the WoSCC database. In general, we observed an increasing trend in the number of publications over the past 20 years. The United States was the most productive and influential country, with the largest proportion of both publications and total citations. Helicobacter, US Department of Veterans Affairs, and Graham, David were the most productive journals, institutions and authors, respectively. Further analysis the co-occurrence and burst detection of keywords revealed that the most common keywords were "Helicobacter pylori," "gastric cancer," and "gastritis," all keywords were divided into eight main clusters, and the most important current research hotspot was the relationship between H. pylori infection and the changes of gut microbiota.
    CONCLUSIONS: The United States has been the most productive and influential country on H. pylori research, and H. pylori-related research remains an active research field. The relationship between H. pylori infection and the changes of gut microbiota is a research hotspot attracting significant attention.
    Keywords:   Helicobacter pylori ; VOSviewer; bibliometric analysis; citespace
    DOI:  https://doi.org/10.1111/hel.12986
  5. Int Ophthalmol. 2023 May 03.
      PURPOSE: Our study aimed to make a bibliometric analysis on Sjögren's syndrome-related dry eye disease (SS-DED), explore its potential research hotspots, and provide critical information for future research interest and undeveloped topics in this field, which can benefit clinicians and researchers.METHODS: We extracted all publications relating to SS-DED from 2003 to 2022 from the Web of Science Core Collection database. Original articles and reviews in English were included. The contributions of different countries, institutions, journals, and authors were compared, and the research hotspots were visualized for network analysis through GraphPad Prism, CiteSpace, and VOSviewer.
    RESULTS: We enrolled a total of 987 publications. The United States contributed the most publications (281, 28.5%), followed by China (157, 15.9%) and Japan (80, 8.11%). Publications from the United States were cited more frequently (13,060 citations), with the highest H-index of 57. China ranked second in the total number of publications, the papers were not cited frequently (3790 citations), and the H-index ranked second (H-index = 31). PLoS One (32, 3.24%) published the most papers, and the University of California system had the highest number of publications (45, 4.56%). Bootsma H from the Netherlands published the most papers. The trend of research hotspots evolved mainly from the basic manifestation to pathogenesis and treatment of SS-DED and paid more attention to distinguishing SS-DED from that dry eye disease without SS.
    CONCLUSIONS: Based on the bibliometric, co-citation, and network analyses in this study, we obtained the annual publications and citations, the growth trends of publications, the productivity of countries, organizations, journals, and authors, high-quality publications, and the emerging hotspots of SS-DED, which may open new doors for promising research directions.
    Keywords:  Bibliometric analysis; Hotspot; Network analysis; Pathogenesis; Sjögren's syndrome-related dry eye disease
    DOI:  https://doi.org/10.1007/s10792-023-02711-4
  6. Medicine (Baltimore). 2023 May 05. 102(18): e33633
      Post-stroke depression (PSD) has served as a severe and common complication leading to a higher level of mortality. Though various studies have been focused on PSD, limited research endeavor has been dedicated to bibliometric analysis in the past. In view of this, the current analysis serves to elucidate the latest status of global research and pinpoint the emerging area of interest for PSD, in order to support further investigation of the field. Publications related to PSD were retrieved from the Web of Science Core Collection database on September 24, 2022, and included in the bibliometric analysis. VOSviewer and CiteSpace software were used to visually analyze publication outputs, scientific cooperation, highly-cited references, and keywords to identify the current status and future trends in PSD research. A total of 533 publications were retrieved. The annual number of publications showed an increasing trend from 1999 to 2022. In terms of country and academic institution, the USA and Duke University have topped the list of PSD research respectively. Meanwhile, Robinson RG and Alexopoulos GS have been the most representative investigators of the field. In the past, researchers focused on the risk factors of PSD, late-life depression, and Alzheimer disease. In recent years, further research effort has been placed on meta-analysis, ischemic stroke, predictor, inflammation, mechanism, and mortality. In conclusion, in the past 20 years, PSD research has been progressing and gaining more attention. The bibliometric analysis successfully unveiled the field's major contributing countries, institutions, and investigators. Furthermore, current hot spots and future trends in the field of PSD were identified, which included meta-analysis, ischemic stroke, predictor, inflammation, mechanism, and mortality.
    DOI:  https://doi.org/10.1097/MD.0000000000033633
  7. Indian J Orthop. 2023 May;57(5): 703-713
      Background: Periprosthetic fractures after prosthetic joint replacement have received increasing attention over the past decades. The purpose of this study was to estimate the trends and state of research in periprosthetic fractures.Methods: Articles on periprosthetic fractures were retrieved from the Web of Science database. Information about each article, including country/region, author, institution, issue, journal, and keywords, was recorded for bibliometric analysis. The analysis included only English-language articles from 2000 to 2021, from 58 countries and regions.
    Results: A total of 1668 original articles meeting the research requirements were obtained. The number of manuscripts on periprosthetic fractures has experienced rapid growth, especially since 2009. Productivity was dominated by the USA, followed by the UK and Germany. The most prolific institution was Mayo Clinic. The most cited article was published by Sharkey, P.F. in 2002. The five most frequent keywords were "periprosthetic fractures", "total hip arthroplasty", " revision", "arthroplasty", "total knee arthroplasty".
    Conclusions: Based on the current trends of globalization, there is a rising trend in publications on periprosthetic fractures, with the largest annual contributions made by the United States. The most influential contributors are researchers from the United States and England. In addition, Journal of Arthroplasty is the journal with the most research in this field. Geriatric trauma and dual mobility are the new hot topics in this field. Together these studies have played a key role in periprosthetic fractures decision-making and management.
    Keywords:  Artificial joint replacement; Bibliometrics analysis; Bibliometrix; Hotspots; Network analysis; Periprosthetic fractures; Research trend; Top cited articles; VOSviewer; Visualization
    DOI:  https://doi.org/10.1007/s43465-023-00863-0
  8. Neuropsychiatr Dis Treat. 2023 ;19 985-1002
      Background: In recent years, there has been a growing body of research suggesting that ASD and ADHD are two disorders that often co-exist. Despite the rapid development of research, little is known about their etiology, diagnostic markers, and interventions, which has led us to review and summarise the development of the field in the hope that this will provide an opportunity to look for future directions.Methods: A bibliometric approach was used to analyse papers in the field of ASD co-morbidities in ADHD on Web of Science from 1991-2022, using CiteSpace and VOSview to map the country/institution, journal, author, co-citation, and keyword networks in the field and to visualise the results.
    Results: A total of 3284 papers were included, showing an increasing trend in terms of posting trends. Research on co-morbidities of ASD has proven to be mainly focused on universities. The USA (1662) published the most relevant literature in this area, followed by the UK (651) and Sweden (388). Lichtenstein P is the most published author (84), and research into the pathogenesis of ASD co-occurring ADHD and related clinical diagnostics is currently at the forefront of the field.
    Conclusion: This analysis identifies the most influential institutions and countries, cited journals, and authors in the field of ASD co-morbid ADHD research. The future direction of ASD co-occurring ADHD should be based on improving case identification, discovering the etiological and diagnostic markers of ASD and ADHD, and finding more effective clinical interventions.
    Keywords:  CiteSpace; VOSviewer; autism; bibliometrics; hyperactivity; visualization analysis
    DOI:  https://doi.org/10.2147/NDT.S404801
  9. Front Psychol. 2023 ;14 1144725
      The concept of multimodal metaphor has generated a growing body of literature over the past decades. However, a systemic review of the domain seems to be lacking in relevant literature. This study, therefore, is an attempt to conduct a bibliometric analysis of the field of multimodal metaphor during 1977-2022, with a focus on 397 relevant publications retrieved from the Web of Science Core Collection (WoSCC) with the visualization tool VOSviewer. Some major quantitative findings are: (i) the number of publications in multimodal research began to surge in 2010 upon the seminal work of Forceville's (2009); (ii) USA, China and Spain are the most productive countries; (iii) journals in the field of advertising, communication and linguistics are important sources of publications; and (iv) eleven clusters of keywords are identified, such as "visual metaphor", "persuasion", "pictures", "impact", "multimodal metaphor", "model", etc., representing crucial areas of interests. We also identified, by qualitative observations, three research trends in multimodal metaphor, driven by cognitive linguistic theory, the theory of pragmatics and visual/multimodal rhetoric theory, respectively. Various theoretical perspectives may shed light on possible further research on multimodal metaphor.
    Keywords:  bibliometric analysis; multimodal metaphor; pictorial metaphor; trends; visual metaphor; web of science (WoS) database
    DOI:  https://doi.org/10.3389/fpsyg.2023.1144725
  10. Biotechnol Genet Eng Rev. 2023 May 05. 1-23
      This study employed bibliometric analysis to examine the current literature on Behcet Syndrome, an autoimmune disorder with complex pathophysiology and inadequate therapeutic options. The researchers collected 3,462 publications related to Behcet Syndrome from 2010 to 2021 via PubMed and conducted co-word and social network analyses to identify research hotspots and potential future directions. The co-word analysis produced a bibliographic data matrix, which revealed 72 high-frequency medical topic title (MeSH) terms. Using repeated dichotomy in the gCLUTO software, the researchers created a visualization matrix that classified the hot topics into six categories over the 12-year study period. The first quadrant contained six mature and well-developed research topics, including biological therapy, immunosuppressive agents, clinical manifestations, complications of Behcet Syndrome, Behcet Syndrome diagnosis, and aneurysm etiology and therapy. The third quadrant comprised four research topics with potential for growth, including Behcet Syndrome genetics and polymorphism, immunosuppressive agents, biological therapy and heart diseases, and thrombosis etiology. The fourth quadrant encompassed the pathophysiology of and quality of life in Behcet Syndrome as well as psychology. In the social network analysis, the researchers identified potential hotspots based on subject keywords close to the network's edge. These included genetic association studies, antibodies, genetic predisposition to disease/genetics, and monoclonal and humanized therapeutic use. Overall, this study's bibliometric analysis of Behcet Syndrome literature from the past 12 years identified unexplored subjects and developing hot spots that could lead to potential research directions for Behcet Syndrome.
    Keywords:  Behcet syndrome; Bibliometric analysis; hot spots; social network analysis; strategic diagram
    DOI:  https://doi.org/10.1080/02648725.2023.2208452
  11. Front Cardiovasc Med. 2023 ;10 1067226
      Background: Inflammasomes have emerged as an important and promising area of investigation in atherosclerosis. This field, however, lacks bibliometric studies. To help understand how basic and clinical research on inflammasomes in atherosclerosis will develop in the future, we used bibliometric analysis to visualize hotspots and trends.Methods: Studies related to inflammasomes in atherosclerosis were collected from the Web of Science Core Collection database. Each study was analyzed bibliometrically and visually. CiteSpace and VOSviewer software were used to generate knowledge maps.
    Results: A total of 894 articles were identified. Sixty-two countries and 338 institutions led by China and the United States contributed to these publications. The leading research institutions were Harvard Medical School and Columbia University. Circulation was the most frequently cited journal in this field. Among the 475 authors determined, Eicke Latz authored the most studies, and Peter Duewell has been cocited the most. NLRP3 inflammasome, NF-kappa B, macrophage and oxidative stress are the most commonly used keywords.
    Conclusion: There has been a blooming of research on inflammasomes in atherosclerosis during the last two decades. Future studies will likely explore the molecular mechanism of inflammasomes in cell death. More compellingly, researchers may further delve into the potential clinical value of affecting pathological changes in atherosclerosis by modulating the initial transcription immune response and intracellular multiprotein assembly process of the NLRP3 inflammasome. Our research will be helpful to scholars focusing on inflammation-a much-needed breakthrough in the pathophysiological alterations of atherosclerosis-with a novel perspective.
    Keywords:  VOSviewer; atherosclerosis; bibliometric; citespace; inflammasome
    DOI:  https://doi.org/10.3389/fcvm.2023.1067226
  12. Front Endocrinol (Lausanne). 2023 ;14 1109456
      Background: Diabetic foot ulcers (DFUs) are one of the most popular and severe complications of diabetes. The persistent non-healing of DFUs may eventually contribute to severe complications such as amputation, which presents patients with significant physical and psychological challenges. Fibroblasts are critical cells in wound healing and perform essential roles in all phases of wound healing. In diabetic foot patients, the disruption of fibroblast function exacerbates the non-healing of the wound. This study aimed to summarize the hotspots and evaluate the global research trends on fibroblast-related DFUs through bibliometric analysis.Methods: Scientific publications on the study of fibroblast-related DFUs from January 1, 2000 to April 27, 2022 were retrieved from the Web of Science Core Collection (WoSCC). Biblioshiny software was primarily performed for the visual analysis of the literature, CiteSpace software and VOSviewer software were used to validate the results.
    Results: A total of 479 articles on fibroblast-related DFUs were retrieved. The most published countries, institutions, journals, and authors in this field were the USA, The Chinese University of Hong Kong, Wound Repair and Regeneration, and Seung-Kyu Han. In addition, keyword co-occurrence networks, historical direct citation networks, thematic map, and the trend topics map summarize the research hotspots and trends in this field.
    Conclusion: Current studies indicated that research on fibroblast-related DFUs is attracting increasing concern and have clinical implications. The cellular and molecular mechanisms of the DFU pathophysiological process, the molecular mechanisms and therapeutic targets associated with DFUs angiogenesis, and the measures to promote DFUs wound healing are three worthy research hotspots in this field.
    Keywords:  bibliometric analysis; diabetic foot ulcers (DFUs); fibroblast; pathophysiological process; therapeutic targets
    DOI:  https://doi.org/10.3389/fendo.2023.1109456
  13. Technol Health Care. 2023 Apr 27.
      BACKGROUND: Various studies have been conducted to analyze data via bibliometric analysis in different dentistry, including prosthetic dentistry. However, these studies evaluated the most cited published articles in dentistry.OBJECTIVE: To analyze and evaluate the characteristic development of several mesh keywords in the Journal of Prosthodontics - Implant, Esthetic, and Reconstructive Dentistry between 1992 and 2022.
    METHODS: The Scopus databases was searched to retrieve the data related to 8 categories, including published articles, most cited documents, authors and organizations, and maximum articles cited during the evaluation period. The data retrieved were exported to a Microsoft Excel sheet and were analyzed using the bibliometrix package. The data were first analyzed for ten years and then for 30 years. The highest of 10 were reported for each category, and co-authorship, reoccurrence, and linked data were also reported.
    RESULTS: 2603 published documents were recorded from the Scopus databases. Articles comprised 87.9% of the total published work, followed by review articles at 5.46%. The most productive decade was between 2013 and 2022. 3793 terms were used during the evaluation period, with the maximum number in 2003-2012 (2481). A total of 5392 keywords were used during 1992-2022, with the highest number (3232) from 2013 to 2022. A total of 6108 authors were acknowledged, with the maximum number (3964) from 2013 to 2022 and the fewest (767) from 1992 to 2002. Authors from different countries increased from 17 countries in 1992-2002 to 52 countries in 2013-2022 (total = 63 countries). Similarly, the number of organizations increased from 312 organizations in 1992-2002 to 1315 organizations in 2013-2022 (total = 1976 organizations).
    CONCLUSION: The current bibliometric analysis delivered a comprehensive overview about more spread research topics and its impactful role in contemporary dentistry, especially prosthetic dentistry.
    Keywords:  Bibliographic analysis; bibliometrix package; citation index; implant; prosthesis
    DOI:  https://doi.org/10.3233/THC-230204
  14. J Orthop. 2023 May;39 50-58
      Introduction: The clavicle is the most frequently fractured bone in the human body, and up to 80% of clavicle fractures occur in the middle third diaphyseal region of the clavicle (midshaft). We conducted a bibliometric analysis to identify and evaluate the 50 most-cited publications pertaining to midshaft clavicle fractures (MCF).Materials and methods: Two independent reviewers conducted separate queries on Web of Science in December 2021 for "midshaft clavicle fractures". The publications yielded were organized from highest to lowest number of citations. We included articles, review articles, and editorial materials and excluded other document types. Both reviewers independently reviewed all abstracts until 50 studies pertaining to MCF were included.
    Theory: We hypothesized that most articles would be published between 2000 and 2019, pertain to outcomes, and those with a greater (lower numeric) level of evidence would correlate with number of citations.
    Results: The most prolific decade was from 2010 to 2019, with 50% (25/50) of articles published. Average citation density was 6.3 ± 5.5 (range, 1.3-33.1), defined as the average number of citations per year since publication. The median level of evidence (LOE) was 3.5 (IQR: 3). One-way ANOVA tests were used to compare the effects of LOE on total citations and citation density. There were statistically significant differences in total citations (F value = 12.07, p = 0.001) and citation density (F value = 21.14, p < 0.001) between LOE groups. The median number of total citations, grouped by LOE of 1 through 5, were as follows: 110, 66, 66, 51, 52.
    Conclusions: This review provides an overview of the 50 most cited papers regarding MCF. This should be used as a reference for physicians and other providers who treat patients with MCF for treatment guidance and for those in teaching roles as a student and resident/fellow educational resource.
    DOI:  https://doi.org/10.1016/j.jor.2023.03.014
  15. Front Oncol. 2023 ;13 1092969
      Background: One of the milestones in bacterial-mediated therapy for cancer, Bacillus Calmette-Guerin (BCG) has been used to treat bladder cancer (BC) for more than 30 years. BCG immunotherapy is now the standard of care for high-grade non-muscle invasive bladder cancer (NMIBC) following transurethral resection.Methods: We searched the Web of Science core collection (WoSCC) database and used bibliometric methods through CiteSpace (version 5.1.R6), VOSviewer (version 1.6.18) and R-Bibliometrix (version R 4.2.1) to analyze and discuss the current status and trends of BCG therapy of BC from 2012 to 2021 in terms of co-occurrence, co-polymerization and visualization.
    Results: A total of 2476 publications were found, with the majority coming from the United States and China. Over the last decade, overall yearly outputs have increased fivefold, from 117 papers in 2012 to 534 records in 2021. Most publications were produced by the University of Texas System. The authors, Ashish M. Kamat of the University of Texas-MD Anderson Cancer Center in the United States, and Shahrokh F. Shariat of Weill Cornell Medical College, were pioneers in this field with the most publications. The journals, Urologic Oncology Seminars and Original Investigations, Cancers and Frontiers in Oncology, have published a dramatic increase in the number of articles, and tumor and urology nephrology research directions have received the most attention from journals. Furthermore, recent research has concentrated on muscle-invasive bladder cancer (MIBC). BCG therapy mechanism, BCG dose and strains, targeted therapy and immune checkpoint inhibitors (ICIs) for BC were attractive research contents, with ICIs (PD-1, PD-L1) being the most popular study point in recent years. With more research on tumor immunology, screening for more reliable biomarkers for precision treatment, and the development of combination regimens of ICIs, targeted treatment of BC stem cells, and personalized BC therapies may be promising areas of immunotherapy research in the coming years.
    Conclusion: The results of this bibliometric study can provide the current status and research trends of BCG therapy for BC in the last decade, and also further complements the research content of bacterial-mediated cancer therapy.
    Keywords:  BCG; bibliometric analysis; bladder cancer; immune checkpoint inhibitors; immunotherapy; web of science
    DOI:  https://doi.org/10.3389/fonc.2023.1092969
  16. J Pediatr Surg. 2023 Apr 11. pii: S0022-3468(23)00245-2. [Epub ahead of print]
      INTRODUCTION: Pediatric surgery is a developing specialty with increasing volume in Latin America. However, the research and scientific activity trends carried out in this region in recent years are unknown. This study aimed to analyze and visualize Latin American research in pediatric surgery from 2012 to 2021.MATERIAL AND METHODS: Bibliometric cross-sectional study of scientific articles on pediatric surgery published by Latin American authors from 2012 to 2021 in Scopus was performed. Statistical and visual analysis was performed with R programming language and VOS viewer.
    RESULTS: 449 articles were found. Observational studies (44.7%; n = 201), case reports (20.4%; n = 92) and narrative reviews (11.4%; n = 51) were found to be the most common study designs. The published articles were predominantly monocentric (73.1%; n = 328), only 17% (n = 76) involved authors from 2 or more countries, and mostly there was no collaboration with high-income countries (80.6%; n = 362). The Journal of Pediatric Surgery was the journal with the highest volume of articles published (n = 37). The most used terms were Laparoscopy, Complications, and Liver Transplantation, and the countries with the highest number of articles published were Brazil and Argentina.
    CONCLUSIONS: This study found a progressive increase in the scientific activity of Latin authors in pediatric surgery from 2012 to 2021. The evidence produced was mainly from observational studies and case reports, predominantly conducted in Brazil. Multinational and international collaboration was low; the most frequent topics of interest were laparoscopy and minimally invasive surgery.
    LEVELS OF EVIDENCE: IV.
    Keywords:  Analysis; Bibliometrics; Latin America; Pediatric surgery; Publications; Visualization
    DOI:  https://doi.org/10.1016/j.jpedsurg.2023.04.003
  17. Accid Anal Prev. 2023 May 02. pii: S0001-4575(23)00137-9. [Epub ahead of print]187 107090
      Recently, researchers have shown a soaring interest in maritime autonomous surface ship (MASS). The reliable design and risk evaluation of MASS is crucial in order to support its safe operations. Hence, keeping abreast of emerging trends in developing MASSs safety and reliability-related technologies is necessary and significant. Nevertheless, a comprehensive literature review focused on this realm is currently lacking. On this premises, based on the 118 selected articles (consisting of 79 journal articles and 39 conference papers) between 2015 and 2022, content analyses and science mapping were conducted in this study from the aspects of journal sources, keywords, countries and institutions, authors, and citations of these publications. The bibliometric analysis aims to uncover several characteristics in this area such as the mainstream journals, research trends, knowledge contributors, and their cooperation relationships. Based on this, the research topic analysis was conducted from five facets including mechanical reliability and maintenance, software, hazard assessment, collision avoidance, communication and human element. It is suggested that the Model-Based System Engineering (MBSE) and Function Resonance Analysis Method (FRAM) could be two potential practical methods for future research risk and reliability analysis for MASS. This paper provides insights into the current state-of-the-art of risk and reliability research in MASS, including current research topics, gaps and future directions. It can also serve as a reference for related scholars.
    Keywords:  Literature review; MASS; Risk and reliability analysis; Science mapping; Scientometric analysis
    DOI:  https://doi.org/10.1016/j.aap.2023.107090
  18. Heliyon. 2023 Apr;9(4): e15438
      There is a significant increase in the literature on learning resources in Higher Education (HE) but very limited evidence of studies that have taken a global overview of the context, range, and emerging trends from the previous research. This study aims to conduct a Scientometric analysis of research articles to accommodate a global overview and research trends under the theme of learning resources in HE. 4489 scientific articles were obtained as the dataset from the Web Of Science database between 1970 and 2022. Network maps and critical data were obtained by conducting co-authorship analysis for authors, organisations and countries and co-occurrence analysis for keywords from the VOSviewer software. The study revealed that the USA had a significant research input, and Salamin, N. from the University of Lausanne was recognised as the most frequently published author. The University of Illinois, USA, has the highest contribution to research articles, and the most popular research hotspots and trends were e-learning, Education, Academic libraries, Learning resources, and Cloud computing. However, the most critical finding from the study is that there needs to be real collaboration within the research theme and suggests ways to improve collaborations to enhance learning resources in HE. This study may be the first to conduct a scientometric analysis of Learning Resources in Higher education. This study offers valuable insight to academics, academic institutions, researchers, policymakers and pedagogical statutory bodies to understand the current context of learning resources in HE and recognise further develop research, collaborations and policies by considering critical findings from the study.
    Keywords:  Digital learning; Higher education; Learning resources; Scientometric; UK; VOSViewer
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e15438
  19. J Ultrasound Med. 2023 May 02.
      Low-intensity ultrasound (LI-US) is a non-invasive stimulation technique that has emerged in recent years and has been shown to have positive effects on neuromodulation, fracture healing, inflammation improvement, and metabolic regulation. This study reports the conclusions of a bibliometric analysis of LI-US. Input data for the period between 1995 and 2022, including 7209 related articles in the field of LI-US, were collected from the core library of the Web of Science (WOS) database. Using these data, a set of bibliometric indicators was obtained to gain knowledge on different aspects: global production, research areas, and sources analysis, contributions of countries and institutions, author analysis, citation analysis, and keyword analysis. This study combined the data analysis capabilities provided by the WOS database, making use of two bibliometric software tools: R software and VOS viewer to achieve analysis and data exploration visualization, and predicted the further development trends of LI-US. It turns out that the United States and China are co-leaders while Zhang ZG is the most significant author in LI-US. In the future, the hot spots of LI-US will continue to focus on parameter research, mechanism discussion, safety regulations, and neuromodulation applications.
    Keywords:  VOS viewer; bibliometric analysis; low-intensity focused ultrasound; low-intensity pulsed ultrasound; low-intensity ultrasound; neuromodulation; web of science
    DOI:  https://doi.org/10.1002/jum.16245
  20. Front Cell Infect Microbiol. 2023 ;13 1147265
      Background: A unique subset of people living with HIV, known as elite controllers, possess spontaneous and consistent control over viral replication and disease progression in the absence of antiviral intervention. In-depth research on elite controllers is conducive to designing better treatment strategies for HIV. However, comprehensive and illuminating bibliometric reports on elite controllers are rare.Methods: Articles on elite controllers were retrieved from the Web of Science Core Collection. A visualized analysis of this domain was conducted by CiteSpace software. Taking count, betweenness centrality, and burst value as criteria, we interpreted the visualization results and predicted future new directions and emerging trends.
    Results: By December 31, 2022, 843 articles related to elite controllers had been published. The largest contributors in terms of country, institution, and author were the United States (485), Univ Calif San Francisco (87), and Walker B.D. (65), respectively. Migueles S.A. (325) and Journal of Virology (770) were the most cocited author and journal, respectively. Additionally, by summarizing the results of our CiteSpace software analysis on references and keywords, we considered that the research hotspots and frontiers on elite controllers mainly focus on three aspects: deciphering the mechanisms of durable control, delineating the implications for the development of treatments for HIV infection, and highlighting the clinical risks faced by elite controllers and coping strategies.
    Conclusion: This study performed a bibliometric and visual analysis of elite controllers, identified the main characteristics and emerging trends, and provided insightful references for further development of this rapidly evolving and complex field.
    Keywords:  CiteSpace; HIV; bibliometric analysis; elite controllers; research hotspots; visualized analysis
    DOI:  https://doi.org/10.3389/fcimb.2023.1147265
  21. Cell Death Discov. 2023 May 01. 9(1): 143
      Vascular endothelial is considered to be a key factor in the pathogenesis of erectile dysfunction (ED). The purpose is to reveal the research trend of the field of ED and vascular endothelium. In addition, the goal is to discover the role and mechanism of vascular endothelium in ED. Bibliometrics and visualization methods based on CiteSpace were selected. We conducted the co-authorship analysis of countries, institutions and authors, co-occurrence analysis of keywords, and co-citation analysis of literature and authors through CiteSpace 6.1.R3. 1431 articles from Web of Science Core Collection (WOSCC) were included in the analysis from 1991 to 2022. We found some influential and cutting-edge nodes in each map, including countries, institutions, authors, articles, etc. Stem cell, therapy, oxidative stress, cavernous nerve injury, radical prostatectomy, fibrosis, erectile function, mesenchymal stem cell, and apoptosis may be hot keywords. In conclusion, the efficacy and mechanisms of stem cells and their derivatives in the treatment of diabetes (DM) ED and cavernous nerve injury (CNI) ED are the future research trends. Stem cells therapy for ED is a hot spot in this field, which side notes that stem cells may work mainly through improving endothelial function. Vascular endothelial cells and VEGF may repair nerve and cavernous smooth muscle directly or indirectly, and finally polish up erectile function.
    DOI:  https://doi.org/10.1038/s41420-023-01443-9
  22. Asian J Surg. 2023 May 04. pii: S1015-9584(23)00549-3. [Epub ahead of print]
      
    Keywords:  Bibliometric analysis; Cognitive decline; Neurosurgery
    DOI:  https://doi.org/10.1016/j.asjsur.2023.04.038
  23. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2023 Apr 26. 1-26
      Detection of perfluorinated compounds (PFCs) in the environment has been a global concern because of the risk they pose due to their endocrine-disruptive properties. This study analyzed the global trends and research productivity of PFCs from 1990 to 2021. A total number of 3256 articles on PFCs were retrieved from the Web of Science focusing on different environmental and biological matrices. An increase in the productivity of research on PFCs was observed during the survey period which indicates that more research and publications on this class of contaminants are expected in the future. Evaluating the most productive countries and the number of citations per country on PFCs research shows that China and the United States of America were ranked in first and second places. It was also observed that research on PFCs received the most attention from scientists in developed countries, with little research emerging from Africa. Hence, research on PFCs in developing countries, especially low-income countries should be promoted. Consequently, more research programs should be implemented to investigate PFCs in countries and regions where research on these contaminants is low. The study will help researchers, government agencies and policymakers to tailor future research, allocation of funds to PFCs research and countries' collaboration.
    Keywords:  Africa; Perfluorinated contaminants; developed countries; environment; web of science
    DOI:  https://doi.org/10.1080/10934529.2023.2203639
  24. Int J Nurs Sci. 2023 Apr;10(2): 268-275
      Objectives: To analyze and summarize the research hotspots and advancement of post-traumatic growth (PTG) over the past 15 years based on co-word analysis of keywords, and provide references for PTG-related research and clinical intervention.Methods: All studies related to PTG were retrieved from PubMed and Web of Science (WOS) from January 2013 to July 2022. A total of 11 Medical Subject Headings (MeSH) and keywords were used to identify qualified studies. Bibliographic Item Co-occurrence Matrix Builder (BICOMB; version 2.0) was used to conduct high-frequency keywords extraction and matrix setup, Graphical Clustering Toolkit (gCLUTO; version 1.0) was employed to perform clustering analysis, and SPSS (version 25.0) was used to carry out strategic diagram analysis.
    Results: A total of 2,370 publications were selected, from which 38 high-frequency keywords were extracted. The results revealed six research hotspots on PTG during the period from 2013 to 2022, including research on i) emotional reactions after negative life events, ii) PTG among cancer survivors, iii) rumination and resilience after trauma, iv) PTG among children and adolescents, v) role of social support and coping strategy in PTG, and vi) association between PTG and quality of life.
    Conclusions: This co-word analysis effectively reveals an overview of PTG over the past 15 years. The six research categories deduced from this study can reflect that the research content in the field of PTG is abundant, but some research topics have not yet been mature. The findings of this study are of great value to future investigations associated with PTG.
    Keywords:  Co-word analysis; Hotspots; Post-traumatic growth; Survivors; Trends
    DOI:  https://doi.org/10.1016/j.ijnss.2023.03.001
  25. Sch Psychol. 2023 May 04.
      To understand the evolution and current status of qualitative research in School Psychology, we reviewed 4,346 articles published across seven school psychology journals between 2006 and 2021. The bibliometric analysis indicates that publication of qualitative research has increased over the years, but remains small (3%) when seen against the total volume of journal publications. Less than 5% of articles in all but one journal were qualitative. The most commonly explored topic was diversity, equity, and social justice accounting for 23% of the qualitative articles. In total, 55% of the studies were conducted in the United States. Although many studies did not specify participants' race and gender, the most commonly reported research participants were K-12 students, female, White, and from the United States. We discuss these findings and provide recommendations. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
    DOI:  https://doi.org/10.1037/spq0000548
  26. Environ Sci Pollut Res Int. 2023 May 04.
      As the severity of global waste pollution continues to escalate, governments are increasingly prioritizing the promotion of waste sorting. This study engaged in the literature mapping of waste sorting and recycling behavior research currently available on the Web of Science using CiteSpace. First, studies on waste sorting behavior have grown rapidly since 2017. The top three continents publishing on this topic were Asia, Europe, and North America. Second, the top journals, Resources Conservation and Recycling and Environment and Behavior, were important to this field. Third, analyses of waste sorting behavior were mainly conducted by environmental psychologists. Ajzen had the highest co-citation count, as the theory of planned behavior has widely been used in this field. Fourth, the top three co-occurring keywords were "attitude," "recycling behavior," and "planned behavior." There was also a recent focus on "food waste." The research trend was found to be refined and accurately quantified.
    Keywords:  Literature mapping; Recycling behavior; Waste sorting behavior
    DOI:  https://doi.org/10.1007/s11356-023-27295-5
  27. Front Public Health. 2023 ;11 1127891
      Background: Influenza poses a major public health challenge in South-East Asia Region (SEAR). To address the challenge, there is a need to generate contextual evidence that could inform policy makers and program managers for response preparedness and impact mitigation. The World Health Organization has identified priority areas across five streams for research evidence generation at a global level (WHO Public Health Research Agenda). Stream 1 focuses on research for reducing the risk of emergence, Stream 2 on limiting the spread, Stream 3 on minimizing the impact, Stream 4 on optimizing the treatment and Stream 5 on promoting public health tools and technologies for Influenza. However, evidence generation from SEAR has been arguably low and needs a relook for alignment with priorities. This study aimed to undertake a bibliometric analysis of medical literature on Influenza over the past 21 years to identify gaps in research evidence and for identifying major areas for focusing with a view to provide recommendations to member states and SEAR office for prioritizing avenues for future research.Methods: We searched Scopus, PubMed, Embase, and Cochrane databases in August 2021. We identified studies on influenza published from the 11 countries in WHO SEAR in the date range of 1 January 2000-31 December 2021. Data was retrieved, tagged and analyzed based on the WHO priority streams for Influenza, member states, study design and type of research. Bibliometric analysis was done on Vosviewer.
    Findings: We included a total of 1,641 articles (Stream 1: n = 307; Stream 2: n = 516; Stream 3: n = 470; Stream 4: n = 309; Stream 5: n = 227). Maximum number of publications were seen in Stream 2, i.e., limiting the spread of pandemic, zoonotic, and seasonal epidemic influenza which majorly included transmission, spread of virus at global and local levels and public health measures to limit the transmission. The highest number of publications was from India (n = 524) followed by Thailand (n = 407), Indonesia (n = 214) and Bangladesh (n = 158). Bhutan (n = 10), Maldives (n = 1), Democratic People's Republic of Korea (n = 1), and Timor-Leste (n = 3) had the least contribution in Influenza research. The top-most journal was PloS One which had the maximum number of influenza articles (n = 94) published from SEAR countries. Research that generated actionable evidence, i.e., implementation and intervention related topics were less common. Similarly, research on pharmaceutical interventions and on innovations was low. SEAR member states had inconsistent output across the five priority research streams, and there was a much higher scope and need for collaborative research. Basic science research showed declining trends and needed reprioritization.
    Interpretation: While a priority research agenda has been set for influenza at the global level through the WHO Global Influenza Program since 2009, and subsequently revisited in 2011 and again in 2016-2017, a structured contextualized approach to guide actionable evidence generation activities in SEAR has been lacking. In the backset of the Global Influenza Strategy 2019-2030 and the COVID-19 pandemic, attuning research endeavors in SEAR could help in improved pandemic influenza preparedness planning. There is a need to prioritize contextually relevant research themes within priority streams. Member states must inculcate a culture of within and inter-country collaboration to produce evidence that has regional as well as global value.
    Keywords:  SEAR; bibliometric; influenza; pandemic; zoonotic
    DOI:  https://doi.org/10.3389/fpubh.2023.1127891
  28. Adv Radiat Oncol. 2023 Jul-Aug;8(4):8(4): 101219
      Purpose: This analysis investigates whether research productivity during medical school predicts future research productivity during radiation oncology residency.Methods and Materials: At our institution, there have been 20 medical students who graduated between 2005 and 2015 and subsequently completed their residency training in radiation oncology. We built a database of all PubMed-indexed publications in which these former students were the first author or coauthor. Mean publication rates with 95% confidence intervals (95% CI) were computed. The paired t test and McNemar-Bowker test of symmetry were used to examine differences in first-author and coauthor publications between the medical school and residency periods. An ordinal logistic regression model was employed to measure the odds ratio of publishing during residency versus during medical school. A Spearman correlation coefficient was calculated for the relationship between the number of publications during medical school and the number during residency.
    Results: A total of 14 and 60 first-author publications (46 and 117 coauthor publications) were identified for 20 individuals during medical school and residency, respectively. There was an average of 0.7 (95% CI, 0.17-1.23) first-author publications during medical school and 3.08 (95% CI, 1.56-4.44) first-author publications during residency (P = .003). Only 15% (3/20) had ≥2 publications during medical school, and 50% (10/20) had ≥2 publications during residency (P = .012). The Spearman correlation coefficient between research publications before and during residency was .457 (P = .043). The mean number of coauthor publications during medical school and residency was 2.3 (95% CI, 0.92-3.68) and 5.85 (95% CI, 3.50-8.20), respectively (P = .004).
    Conclusions: Based on this retrospective analysis from our institution, student research productivity during medical school, as defined by the number of first-author publications, does correlate with future research productivity during radiation oncology residency.
    DOI:  https://doi.org/10.1016/j.adro.2023.101219
  29. Urol Pract. 2022 Jul;9(4): 340-349
      INTRODUCTION: Our primary aim was to characterize eventual publication of presented American Urological Association (AUA) Annual Meeting oncology abstracts from 1997 to 2017. We hypothesized that the percentage of abstracts presented at the AUA Annual Meeting that became published peer-reviewed manuscripts increased over time.METHODS: AUA Annual Meeting abstracts in "oncology" categories from 1997 to 2017 were identified. A random sample of 100 abstracts per year were assessed for publication. An abstract was considered "published" if 1) first and last author of the abstract were included on publication, 2) abstract and publication shared 1 conclusion, and 3) publication occurred from 1 year prior to the AUA Annual Meeting up to 10 years after. The search was conducted on PubMed® utilizing the MEDLINE® database.
    RESULTS: Over the 20-year observation period, 2,100 abstracts were reviewed and 56.3% were published. The number of journals in which manuscripts were published increased from 1997 to 2017 (R2=0.58, p <0.001), although here wasn't an increased publication rate for AUA Annual Meeting abstracts. Median time to publication was 1.1 years (IQR: 0.6-2.2). Median impact factor (IF) of publications was 3.3 (IQR 2.4-4.7). There was a decrease in median IF with longer interval to publication, from 3.6 within 1 year to 2.8 at more than 3 years (p=0.0003). Publications from multi-institutional abstracts had a higher mean IF (3.7 vs 3.1, p <0.0001).
    CONCLUSIONS: The majority of oncology abstracts presented at the AUA Annual Meeting are published. Despite growth in the number of journals and rise in IF among top urology journals, the rate of publication and IF were stable over time.
    Keywords:  meeting abstracts [publication type]; peer review; periodicals as topic; publishing; urology
    DOI:  https://doi.org/10.1097/UPJ.0000000000000304
  30. Heliyon. 2023 May;9(5): e15532
      As the topic of sustainable development continues to prominence in global affairs, the case for renewable energy has never been stronger. To be regarded as a perfect alternative to conventional (non-renewable) energy sources in many climes, renewable energy, such as solar and wind, shows promise when considering concepts like grid parity. A significant number of studies have been devoted to understanding the concept. However, only a few studies have committed themselves to analysing the research activity carried out on it. This paper will present a bibliometric and empirical review of worldwide grid parity, energy transition, and electricity cost research. To situate the progress in this research area, a detailed search of Scopus was used to identify and situate research development in the field from 1965 until 2021. Using the data extracted from Scopus and VOSviewer for analysis, we explore different aspects of the publications, such as the volume, growth rate, and coverage of published documents, the most influential research papers and journals in this research area, and the most studied research themes in recent years. We also discuss Governmental policies in developed and developing economies that have accelerated the attainment of Grid parity in certain countries. Also, an empirical review of top-down, bottom-up, and artificial neural network approaches to evaluating grid parity was conducted. The study revealed a steady increase in the research articles focused on grid parity, energy transition, and electricity cost research from 2006. The geographic distribution of the publications shows that most of the publications on the subject originated from the USA, Germany, China, United Kingdom, and Spain, raking in 42.2% of the publications. Also, the top 7 authors with the highest document count from Scopus are from Finland, which coincidentally is one of the countries making significant progress in Grid parity attainment. Of the total document count from Scopus, only 0.02% are papers published from African Countries. Could this reluctance to publish research findings on energy transition be one of the reasons for the slow progression of sustainable energy for all in Africa? Therefore, it is imperative now more than ever for more research focusing on the attainment of grid parity, energy transition, and electricity costs for developing countries to be brought to the fore. This article provides a review of state-of-the-art research on the attainment of grid parity and energy transition with a focus on the Levelized Cost of Electricity (LCOE) models of renewable energy sources.
    Keywords:  Energy generation; Grid parity; Levelized cost of electricity; Renewable energy sources; Sustainability; Sustainability development goals
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e15532
  31. Front Oncol. 2023 ;13 1197217
      [This corrects the article DOI: 10.3389/fonc.2023.1082423.].
    Keywords:  bibliometric analysis; computer science; machine learning; non-small cell lung cancer; radiotherapy
    DOI:  https://doi.org/10.3389/fonc.2023.1197217
  32. PLoS One. 2023 ;18(5): e0284403
      Women are under-represented among authors of scientific papers. Although the number of retractions has been rising over the past few decades, gender differences among authors of retracted papers remain poorly understood. Therefore, this study investigated gender differences in authorship of retracted papers in biomedical sciences available on RetractionWatch. Among 35,635 biomedical articles retracted between 1970 and 2022, including 20,849 first authors and 20,413 last authors, women accounted for 27.4% [26.8 to 28.0] of first authors and 23.5% [22.9 to 24.1] of last authors. The lowest representation of women was found for fraud (18.9% [17.1 to 20.9] for first authors and 13.5% [11.9 to 15.1] for last authors) and misconduct (19.5% [17.3 to 21.9] for first authors and 17.8% [15.7 to 20.3] for last authors). Women's representation was the highest for issues related to editors and publishers (35.1% [32.2 to 38.0] for first authors and 24.8% [22.9 to 26.8] for last authors) and errors (29.5% [28.0 to 31.0] for first authors and 22.1% [20.7 to 23.4] for last authors). Most retractions (60.9%) had men as first and last authors. Gender equality could improve research integrity in biomedical sciences.
    DOI:  https://doi.org/10.1371/journal.pone.0284403
  33. Eur J Hum Genet. 2023 May 04.
      This article seeks to highlight the most recent trends and themes in genetic counseling that are of broad interest. A total of 3505 documents were published between 1952 and 2021, with a trend toward increase in paper/year. The most common documents are original articles (2515, 71.8%), followed by review articles (341, 9.7%). Journal of Genetic Counseling publishes the highest number of genetic counseling articles (587, 16.7%), followed by Clinical Genetics (103, 2.9%) and the South American Journal of Medical Genetics (95, 2.7%). Co-occurrence analysis revealed five research themes: genetic testing, cancer, genetic counselor, prenatal diagnosis, and psychiatry. The genetic counselor theme contained most of the recent keywords, including "covid-19," "underrepresented population," "service delivery models," "workforce," "disparities," "service delivery," "professional development," "cultural competence," "access," "diversity," "telemedicine," and "health literacy." Genetic counseling researchers may use these keywords to find topics pertinent to their future research and practice.
    DOI:  https://doi.org/10.1038/s41431-023-01371-3
  34. J Surg Educ. 2023 May 02. pii: S1931-7204(23)00125-3. [Epub ahead of print]
      BACKGROUND: It is important for physicians to be familiar with statistical techniques commonly used in published medical research. Statistical errors in medical literature are common, and there is a reported lack of understanding regarding statistical knowledge necessary for data interpretation and journal reading. As study design has become increasingly complex, peer-reviewed literature poorly addresses and explains the most common statistical methods utilized across leading orthopedic journals.METHODS: Articles from 5 leading general and subspecialty orthopedic journals were compiled from 3 distinct time periods. After exclusions were applied, 9521 remained, and a random 5% sampling of these articles, balanced across journals and years, was conducted yielding 437 articles after additional exclusions. Information regarding the number of statistical tests used, power/sample size calculation, type of statistical tests used, level of evidence (LOE), study type, and study design was collected.
    RESULTS: The mean number of statistical tests across all 5 orthopedic journals increased from 1.39 to 2.29 by 2018 (p = 0.007). The percentage of articles that reported power/sample size analyses was not found to differ by year, but the value has increased from 2.6% in 1994 to 21.6% in 2018 (p = 0.081). The most commonly used statistical test was the t-test which was present in 20.5% of articles, followed by chi-square test (13%), Mann-Whitney analysis (12.6%) and analysis of variance (ANOVA, 9.6%). The mean number of tests was generally greater in articles from higher impact factor journals (p = 0.013). Studies with a LOE of I used the highest mean number of statistical tests (3.23) compared to studies with lower LOE ratings (range 1.66-2.69, p < 0.001). Randomized control trials used the highest mean number of statistical test (3.31), while case series used the lowest mean number of tests (1.57, p < 0.001).
    CONCLUSIONS: The mean number of statistical tests used per article has increased over the past 25 years with the t-test, chi-square test, Mann-Whitney analysis, and ANOVA being the most used statistical tests in leading orthopedic journals. Despite an increase in statistical tests it should be noted that there was a paucity in advance statistical testing within the orthopedic literature. This study displays important trends in data analysis and can serve as a guide to help clinicians and trainees better understand the statistics used in literature as well as identifying deficits within the literature that should be addressed to help progress the field of orthopedics.
    Keywords:  level of evidence; medical education; orthopedic literature; power analysis; randomized control trials; statistical tests
    DOI:  https://doi.org/10.1016/j.jsurg.2023.04.006
  35. Int J Surg. 2023 May 04.
      BACKGROUND: Standards for reporting surgical adverse events vary widely within the scientific literature. Failure to adequately capture adverse events hinders efforts to measure the safety of healthcare delivery and improve the quality of care. The aim of the present study is to assess the prevalence and typology of perioperative adverse event reporting guidelines among surgery and anesthesiology journals.MATERIALS AND METHODS: In November 2021, three independent reviewers queried journal lists from the SCImago Journal & Country Rank (SJR) portal (www.scimagojr.com), a bibliometric indicator database for surgery and anesthesiology academic journals. Journal characteristics were summarized using SCImago, a bibliometric indicator database extracted from Scopus journal data. Quartile 1 (Q1) was considered the top quartile and Q4 bottom quartile based on the journal impact factor. Journal author guidelines were collected to determine whether adverse event reporting recommendations were included and, if so, the preferred reporting procedures.
    RESULTS: Of 1,409 journals queried, 655 (46.5%) recommended surgical adverse event reporting. Journals most likely to recommend adverse event reporting were: 1) by category surgery (59.1%), urology (53.3%), and anesthesia (52.3%); 2) in top SJR quartiles (i.e. more influential); 3) by region, based in Western Europe (49.8%), North America (49.3%), and the Middle East (48.3%).
    CONCLUSIONS: Surgery and anesthesiology journals do not consistently require or provide recommendations on perioperative adverse event reporting. Journal guidelines regarding adverse event reporting should be standardized and are needed to improve the quality of surgical adverse event reporting with the ultimate goal of improving patient morbidity and mortality.
    DOI:  https://doi.org/10.1097/JS9.0000000000000323
  36. Int J Biometeorol. 2023 May 02.
      The climate-health nexus is well documented in the field of biometeorology. Since its inception, Biometeorology has in many ways become the umbrella under which much of this collaborative research has been conducted. Whilst a range of review papers have considered the development of biometeorological research and its coverage in this journal, and a few have reviewed the literature on specific diseases, none have focused on the sub-field of climate and health as a whole. Since its first issue in 1957, the International Journal of Biometeorology has published a total of 2183 papers that broadly consider human health and its relationship with climate. In this review, we identify a total of 180 (8.3%, n = 2183) of these papers that specifically focus on the intersection between meteorological variables and specific, named diagnosable diseases, and explore the publication trends thereof. The number of publications on climate and health in the journal increases considerably since 2011. The largest number of publications on the topic was in 2017 (18) followed by 2021 (17). Of the 180 studies conducted, respiratory diseases accounted for 37.2% of the publications, cardiovascular disease 17%, and cerebrovascular disease 11.1%. The literature on climate and health in the journal is dominated by studies from the global North, with a particular focus on Asia and Europe. Only 2.2% and 8.3% of these studies explore empirical evidence from the African continent and South America respectively. These findings highlight the importance of continued research on climate and human health, especially in low- and lower-middle-income countries, the populations of which are more vulnerable to climate-sensitive illnesses.
    Keywords:  Climate and health; Diseases; Health biometeorology; Human; Meteorological variables; Publications
    DOI:  https://doi.org/10.1007/s00484-023-02466-8
  37. Heliyon. 2023 Apr;9(4): e15468
      Recent research has documented the interest of organizations in training their staff in soft skills, but few studies have been found. Therefore, the objective of this research was to analyze 753 publications in the Scopus database related to soft skills in staff training during the period 1999-2021. These documents were analyzed to identify the main information, the most explored areas, and a future research agenda; all under a bibliometric and bibliographic approach with the help of RStudio and VOSviewer software. The results showed that the keywords with the most co-occurrence were personnel training (n = 110) and soft skills (n = 79). The year with the most documents was 2021 (n = 121). The country with the most publications was the United Kingdom (n = 199). Medicine is the subject area with the most documents (n = 278) and the Article is the type of document with the most studies (n = 566). Eleven areas of further exploration were identified: "Soft skills in software engineering at the higher education level", "Soft skills and communication", "Soft skills and engineering education", "Soft skills in virtual environments", "Soft skills in machine learning", "Serious games in teaching soft skills", "Soft skills for problem-based learning", "Soft skills for project management", "Soft skills and technical skills", "Project-based learning for the assessment of soft skills" and "Soft leadership skills". Five potential areas for future research were derived: soft skills in collaborative work (CSCL), soft skills in computer-aided collaborative work (CSCW), facial expressions as a mirror of soft skills, soft skills for employability and Professional Development Plan (PDP) to assess soft skills. In conclusion, this Review type document on soft skills in personnel training helped to identify the most studied topics during the evaluated period, as well as to identify the little explored topics for future research.
    Keywords:  Employment; Human resource management; Soft skills; Staff training; Technical skills
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e15468
  38. Emerg Microbes Infect. 2023 May 05. 2210696
      Following the current outbreak, the mpox virus (formerly: monkeypox virus) is a highly threatening pathogen with public health significance, although mpox is still considered a neglected disease. Previously confined mainly to Africa, the virus spread globally in 2022. However, knowledge about mpox is limited, causing a distorted perception of the disease. Therefore, this study aimed to collect all information on scientific mpox publishing and to analyze them according to their chronological, geographical, and epidemiological patterns. It was not until the global outbreak that the relatively small number of publications was replaced by the immense increase in annual publication numbers. The most important player is the USA with a central role in international networking. They collaborated mainly with the Democratic Republic of Congo, a primary endemic country where the first viral clades were determined. Nigeria and other African countries were also represented, although mainly in the form of co-authorships. The fact that few of the first authors are from low- or middle-economic countries demonstrates the need to promote equitable networking at the global level and their support for surveillance and targeted immunization programs.
    Keywords:  Authorship; Collaboration; Monkeypox; Outbreak; Publication analysis
    DOI:  https://doi.org/10.1080/22221751.2023.2210696
  39. Eur J Radiol. 2023 Apr 11. pii: S0720-048X(23)00144-4. [Epub ahead of print]163 110830
      PURPOSE: The purpose of this study was to conduct a meta-research of radiomics-related articles for the publication of negative results, with a focus on the leading clinical radiology journals due to their purportedly high editorial standards.METHODS: A literature search was performed in PubMed to identify original research studies on radiomics (last search date: August 16th, 2022). The search was restricted to studies published in Q1 clinical radiology journals indexed by Scopus and Web of Science. Following an a priori power analysis based on our null hypothesis, a random sampling of the published literature was conducted. Besides the six baseline study characteristics, a total of three items about publication bias were evaluated. Agreement between raters was analyzed. Disagreements were resolved through consensus. Statistical synthesis of the qualitative evaluations was presented.
    RESULTS: Following a priori power analysis, we included a random sample of 149 publications in this study. Most of the publications were retrospective (95%; 142/149), based on private data (91%; 136/149), centered on a single institution (75%; 111/149), and lacked external validation (81%; 121/149). Slightly fewer than half (44%; 66/149) made no comparison to non-radiomic approaches. Overall, only one study (1%; 1/149) reported negative results for radiomics, yielding a statistically significant binomial test (p < 0.0001).
    CONCLUSION: The top clinical radiology journals almost never publish negative results, having a strong bias toward publishing positive results. Almost half of the publications did not even compare their approach with a non-radiomic method.
    Keywords:  Meta-research; Negative results; Publication bias; Radiomics; Systematic review; Texture analysis
    DOI:  https://doi.org/10.1016/j.ejrad.2023.110830
  40. J Plast Reconstr Aesthet Surg. 2023 Apr 18. pii: S1748-6815(23)00213-9. [Epub ahead of print]81 91-93
      
    Keywords:  Equity; Female under-representation; Gender diversity; Gender gap; Gender inequality; Human capital
    DOI:  https://doi.org/10.1016/j.bjps.2023.04.056
  41. Can J Nurs Res. 2023 May 03. 8445621231172621
      BACKGROUND: Predatory publishers and their associated journals have been identified as a threat to the integrity of the scientific literature. Research on the phenomenon of predatory publishing in health care remains unquantified.PURPOSE: To identify the characteristics of empirical studies on predatory publishing in the health care literature.
    METHODS: A scoping review was done using PubMed/MEDLINE, CINAHL, and Scopus databases. A total of 4967 articles were initially screened; 77 articles reporting empirical findings were ultimately reviewed.
    RESULTS: The 77 articles were predominantly bibliometric analyses/document analyses (n = 56). The majority were in medicine (n = 31, 40%) or were multidisciplinary (n = 26, 34%); 11 studies were in nursing. Most studies reported that articles published in predatory journals were of lower quality than those published in more reputable journals. In nursing, the research confirmed that articles in predatory journals were being cited in legitimate nursing journals, thereby spreading information that may not be credible through the literature.
    CONCLUSION: The purposes of the evaluated studies were similar: to understand the characteristics and extent of the problem of predatory publishing. Although literature about predatory publishing is abundant, empirical studies in health care are limited. The findings suggest that individual vigilance alone will not be enough to address this problem in the scholarly literature. Institutional policy and technical protections are also necessary to mitigate erosion of the scientific literature in health care.
    Keywords:  Joanna Briggs criteria; PRISMA; qualitative; quantitative; scholarly literature; scoping review; unethical publishing practices
    DOI:  https://doi.org/10.1177/08445621231172621